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Sixteen-year-old Katie Buckley arrives at the Royal Manchester Children's Hospital for a bone marrow transplant, involving marrow taken from her sister Ginny, following the failure of chemotherapy to cure her acute myeloid leukaemia. Doctors reveal whether the brain surgery on toddler Amelia, who featured in the first series, has been successful, and four-year-old Sean giggles his way through A&E.
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