Anti Adrenergic Drugs (Part 01)| Adrenergic Receptor Blocker | Sympatholytic Drugs | Pharmacology

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A sympatholytic (or sympatholytic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system. Antiadrenergic agents inhibit the signals of epinephrine and norepinephrine. They are primarily postsynaptic adrenergic receptor antagonists (alpha and beta-adrenergic receptor antagonists, or "blockers"), inhibiting the downstream cellular signalling pathways of adrenergic receptors. Antiadrenergic agents inhibit the activity of the sympathetic nervous system. They act by blocking adrenergic receptors in target organs or by inhibiting the synthesis, storage, or release of endogenous catecholamines (mainly norepinephrine). This class of medications is most commonly used for the treatment of ischemic heart disease and hypertension, although antiadrenergic agents may also be used for urinary retention secondary to benign prostatic hyperplasia and for psychiatric conditions such as anxiety disorders and post-traumatic stress disorder.
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Really awesome and understandable video sir. You should have been my teacher. But still it's ok, please keep uploading such videos so that my Pharmacology study becomes easier.

[@solutionpharmacy]

Young Futures Thank you so much dear.

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Amazing...What I need is an explanation of the method......Thank you so much sir.....u r great.... upload more videos like that for us....👍🙏

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You are great sir what an explanation 🙏 keep uploading videos 🙂

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[@mohanlalchoudhary1866]

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[@sandrakurian4734]

If you can then pls rply me that anti adrenergics and noradrenergics are same or not

[@solutionpharmacy]

Almost

[@drasif2982]

Great.. Sir could you tell me what's the difference between antagonist and sympathomimetics

[@solutionpharmacy]

Uploaded

[@drasif2982]

Thank you Sir

[@riyapandey7763]

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[@solutionpharmacy]

Thank you so much for your support and feedback

[@jyotirmayeedas2492]

Thank you sir

[@nikhilpandey4007]

Sympatholytics padna h but samj ni aara aapki ye wali kare ya iski agli wali dono me aapne heading same hi rakhi h

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Thank you so much. These are also useful for MBBS

[@amarshah9769]

@@solutionpharmacy its helpful for mbbs bt complete all topics some parts are still remaining for mbbs.

[@abdulrahman2654]

Sir 1 point mai alfa anti hypertension ka pharmacological effect hai or 5 point mai anti hypertension ka side effect please reply Sir

[@pragatibasawnathe6255]

Sir alpha blocker antihypertensive role play krty........ But as exaplined in point 5 ...blood volume increase ho rha.. Toh hypertension cause hoga nn..... Plz explain

[@ifrasyed8225]

Very good lecture,plz sir explain us full pharmacology from starting.

[@solutionpharmacy]

We have made video and uploaded already from starting. Please check channel

[@mayankmehendiratta999]

Na+ retention se renin activate hoga which further activates RAAS System resulting in increased blood pressure??

[@solutionpharmacy]

Mayank Mehendiratta Na se jo BP increase hoga wo negetive feedback mechanism se control karne ke kosis krega.

[@mayankmehendiratta999]

@@solutionpharmacy means even after release of renin... overall hypotension occurs... Am i ryt?

[@solutionpharmacy]

Mayank Mehendiratta not hypotension. Release of renin is dependent on baroreceptor and if it can not balance then renin release will cause hypertension.

[@bhavyajain26912]

@@solutionpharmacy sir, u're right, aapne already explain kiya hua hai, in Blood pressure controlling mech. Jisme hamne "baroceptor" and "Raas" pada tha

[@raginibansal2775]

Thnk u sir for clear my doubts

[@tvindustry3600]

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[@zazahere_]

Is 5th point it's side effect ?

[@abshala563]

Sir thoda wo smjh nhi aya ki blood flow kum hone se na+ reabsorption kaise badh jayega

[@Piya_917]

Sir please ye clear krdo ki effect of alpha 1 blockers ka benign prostate hypertrophy pr kya effect hota h... I m so confused🙁

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[@Kim-qk3sw]

Sir non selective alpha blocker alpha beta dono pe kar skta h kaam ..plz explain this

[@solutionpharmacy]

Yes

[@khusbomishra1220]

Thanks so much sr these are also useful for medicinal chemistry

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Khusbo mishra Thank you

[@hulk_gaming3171]

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[@MOHITSAINI-ku7hp]

Sir Adregenic drug main heart rate increase hoti hai To anti Adregenic main decrease honi chahiye But aapne dono main increase bataya aisa kyu

[@raam7446]

That's not heart rate that's cardiac output .and anti adrenergic drugs doesn't act on cardiac stimulation

[@anujaloya4846]

It's really very helpful sir👍

[@solutionpharmacy]

Thanks alot

[@sangeetasehrawat9494]

Sir..agr antiadrenergic drug vessel ko dilate krte h...fir apne btaya ki renal blood flow hota h ..tb blood volume increase hota h..isse to fir hypertension lead krega..plz explain

[@solutionpharmacy]

Sahi socha aapne but ek baar slowly se pura video apne doubt ko dhyan me rakh kar dekhiye fir nahi samjh aaye to bataiyega.

[@raam7446]

Peripheral vascular resistance decresed ,than after load decrease ,leads increase in cardiac output ..... But sir u write wrong i think ,if it is plz tell me i am confused

[@solutionpharmacy]

I will check

[@girishyt8207]

Thanks sir very useful video 🤗🤗👍👍❤️❤️

[@solutionpharmacy]

Thank you

[@girishyt8207]

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[@DrxRamdevRamdev]

Thanks dear sir

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Welcome

[@saurabhsinghshakya5314]

Sir ye sufficient h Na according to kd Tripathi...reply me

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Cant say it is sufficient but its useful

[@saurabhsinghshakya5314]

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[@pratiksha4904]

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Pratiksha Sudrik Thank you for your feedback.

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Most welcome

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Dinesh Choudhary my pleasure

[@pateltapasvi7277]

Sir 1 request hai me Cholinergic/Anti cholinergic. & Adrenergic/Anti adrenergic. Ki pharmacological action me confuse ho jata hu to me use kaise yaad rkh sku aapke paas koi trick jaisa kuch hai to pls help me sir...........

[@solutionpharmacy]

Tricks to nahi hai. Aap ek baar pure parts dekhiye sab samjh aa jayega

[@idrishansari8184]

Thank you sir. .. Sir Analysis k basic introduction described kar dijiye, please. ..

[@solutionpharmacy]

Idrish Ansari Ek baar pharmacology complete hone dijiye fir ek ek karke sare subj upload ho jaaega

[@idrishansari8184]

@@solutionpharmacy okay sir. ..

[@RajSingh-jz5ll]

What is the diff btw antagonist adrenergic and anti adrenergic???? Are antagonist adrenergic is anti adrenergic? Coz both are blocking

[@solutionpharmacy]

Yes

[@raviroshan5266]

Sir as I am think Anti-adnergic symptoms is some common also in cholinergic..??...I am right or not sir...🤔

[@solutionpharmacy]

Yes

[@garimar2984]

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[@solutionpharmacy]

My pleasure

[@MBBSLOVER786]

Tysm sir

[@DrVPSingh-ng8id]

Good job

[@rx_pratapmejrani3133]

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[@SaleemKhan-gv1me]

Thank you Sir.

[@zeenatansari9502]

Sir aap ne bataya ki 1) Vasodilation ki wajah se BP decrease hoga But on other side... 2) GFR rate decrease ho raha h jiski wajah se Na+/ H2O retention ho raha h and blood volume increase hoga But.... Agar blood volume increase hoga to Blood pressure bhi increase hoga na?? Dono point ek dusre ko oppose kar rahe h !!! Sir please clear the doubt, I'm confused!!

[@solutionpharmacy]

Zeenat Ansari Maine kaha pe kaha ki dilation ki wajah se BP badega. Please let me know the time

[@solutionpharmacy]

Zeenat Ansari blood vol. increase hoga to bp bhi badega. Aap sahi bol rahe hai

[@zeenatansari9502]

@@solutionpharmacy Sir in point no. 1) Alpha blocker acts as vasodilator and reduces peripheral resistance results in fall in BP

[@solutionpharmacy]

Zeenat Ansari Its alfa Blocker. Its right.

[@solutionpharmacy]

Now i got your question. See there are two main mechanism of BP. peripheral and other. Basoconstriction at on peripheral resistance. It will not dilate too much to affect GFR. reduction upto a optimum level.

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[@solutionpharmacy]

Sorry we cant make random video

[@deekshasharma17]

Sirr.. I have 1 ques: Is alpha2 blockade-enhance the release of noredrenaline ....how?

[@solutionpharmacy]

Yes

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Blocking reuptake ,

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sir...thnku for dis

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[@solutionpharmacy]

tanya shukla Bilkul par pahle hamara syllabus complete ho jaye.

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Sir plz upload video on MCQ s of pharmacology for d pharmacy

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Check description box. Cology is not different for B or D pharma

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My pleasure

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Sir ye bsc nuring 2 nd year m pura kaam aayega

[@solutionpharmacy]

Manish Dev P. V good. Actually mujhe Nursing ke syllabus ki jankari nahi hai. Ager ye aapke kaam ka hai to bahut hi achhi baat hai.

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Sir medicinal chemistry ke basic chiz ko samjhyie sir

[@solutionpharmacy]

Sorry i am teaching cology only

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Sir plzz upload video on history and development of pharmacy

[@solutionpharmacy]

Aatanka Neupane Already uploaded. Please find in our channel.

[@arjunrana6465]

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[@solutionpharmacy]

arjun rana my pleasure

[@anupriyakumari6326]

sir plz provide some mcq questions at the end of topic

[@solutionpharmacy]

At the end of every unit (Not topic) we used to upload all model question paper as per the new PCI syllabus. We have uploaded unit 1 and 2 model question papaer. Please do find in our channel.

[@Doctor_Shahnawaz]

thank you sir .......

[@solutionpharmacy]

My pleasure

[@aliyayaqoob6373]

plz write the total number of parts each topic has with every video.

[@solutionpharmacy]

Yes your suggestion is good. I will try to do it

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[@solutionpharmacy]

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Sir plzz pharmacy 4 sem ke cology ke baad ho sake to ceutics ke bhi video upload karo na

[@solutionpharmacy]

Dhruvin Patel ok

[@mohamedabdull7326]

Other we don't understand india language and we need to get knowledge so please sir can you English language during teaching?

[@solutionpharmacy]

Please visit our new channel for pharmacology lectures in English (Started From 01/12/2020). Link- Complete Pharmacology Topics (English) kzbin.info/aero/PLOsge3l7t_CTpZW0qDKEHoYyYBTYPozex Channel list - kzbin.info

[@suneelverma9389]

Sir iska notes nahi h ....

[@solutionpharmacy]

Ha hum notes nahi de pte hai sabka isiliye video saral bhasha me banata hu taki aap sab apna notes apne apne hisab se bana sakein.

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Some concepts r not right

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Please let me know which is wrong as per your opinion with reference

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❤

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Sir video ko chota bna ke thoda or sahi se smjya kijiye

[@solutionpharmacy]

All videos are already uploaded

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Thats against the copy right act

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