Specific (Adaptive) Immunity | Humoral and Cell-Mediated Responses

[@halqthedarktemplar]

To add a bit to the cell-mediated response for people reading the comments, the infected cell presents the antigen via the MHC-I (instead of the MHC-II of the APC cells) and the T-killer lymphocyte uses the CD8 receptor for that antigen

[@naylacalvin2507]

Thank you it was actually helpful

[@BirhanuChalie-d7n]

Fantastic lecture and comments.

[@zizojaezekeom3565]

But T8 lymphocytes need T4 lymphocytes so how did T4 lymphocytes get activated if they don't recognize CMH1

[@Charles-uk6ur]

@@zizojaezekeom3565 well the macrophage has MHii that presents the antigen,the MHii and is recognised by cd4.while the affected cell has MH i that it presents the antigen with and is recognised by cd8 in short macrophage MHii - cd4 affected cell MHi - cd8

[@saniyaiqbal]

actually mhc1 attaches with cd8+ and the antigen which is represented binds with TCR

[@chefmittens3056]

This was insanely precise. I love that you follow such a linear path for something involving a lot of steps at once. Seriously thank you thank you thank you. I've watched a lot of good videos on immunity but yours was the only one to truly make it fully understandable.

[@SiebertScience]

Thanks so much for the kind words! Glad you found it helpful.

[@MoodSwing-x1s]

Yes, this is so true thank you😊

[@fimpero994]

I've been trying to get my head around this topic for months now and I stumbled across this video, ive never heard it explained so well and so precisely yet in a way so easy to understand. You're an extraordinary teacher, THANKS!

[@annguy5563]

This is so amazing, you explain what my 3 hours lectures couldn't in 10 minutes.

[@puneet1173]

Thank you so much. I have spent hours looking for videos to help me on this topic and now you have made it crystal clear in my head. Please continue to make more videos they help so much

[@SiebertScience]

Aw, thank you for the comment! Glad it was helpful!

[@SyenPie]

EXACTLY. This was by far the best video I've found on this topic, presented in such a CLEAR and organized way! This man truly has a gift for teaching.

[@charlespolino]

Can't begin to express how excited I am to have come across your channel! 60 slides all explained in one amazing video, and everything just clicked in my head. Thanks Siebert!!

[@flygirlkc]

Thank you for the "clear as glass" explanation!

[@SiebertScience]

You're welcome!

[@wachimingoxd]

My god, what a crystal clear explanation for such a convoluted concept, spent the whole afternoon trying to understand the humoral response until I came across your video, many thanks!

[@TiaDimi]

I have been researching this topic over the past week for an assignment, struggling to find anything as clear and helpful as this video by a mile. This video literally feels like the best video on the whole internet for explaining B cell and T cell functions and specific immune responses in general. The detail is perfect, the whole video flows. Thank you so much, I really appreciate your work!

[@haileyellingson6318]

So helpful in helping me remember all the cells and their functions! Thank you!

[@jennyrios9535]

Reviewing my Physiology notes to take my TEAS exam. I looked through so many videos that were either too complex or too simple. This was perfect! Loved the artwork and the clean separation of processes. Thank you!!!

[@SiebertScience]

You're welcome! I'm glad you found it helpful. Yeah, it's hard to find resources at the right level for a lot of this stuff.

[@tiffany6376]

I got frustrated learning about immune system, but your video is truly a big help for me to understand it better. Hopefully u will continue making new videos cause I gonna be a big fan of your

[@SiebertScience]

Glad it helped! I plan to keep making more videos!

[@johnaghogho2435]

This was every thing I needed... Thanks for being available to help out

[@DestineeMadrigal]

Nursing student here! Thank you so much for these videos!! You are a hero!

[@TheTiss1982]

This man needs a medal for this breakdown! I’m passing this exam! Talk about confidence he just gave me

[@mulukenm268]

What an attractive and genius way of presenting!! Please continue doing it for other parts of pathology and physiology. You made the subject matter very edible 😀😀😀

[@SiebertScience]

Thanks! I plan to keep making videos 👍🏼

[@tajharelstewart5854]

Another great video, I love this guy. So smart and explains everything so thoroughly and easy to understand 10/10 teacher

[@mondelwane8592]

I wish you were making videos 4 years ago, my goodness man you are a life saver

[@ratanraj743]

You are wonderful ... clear and crisp ... wish youtube present u to the needful learners in the manner how our cells present the antigens for betterment of body :)

[@SiebertScience]

Thanks! I hope KZbin listens to your advice, haha! :)

[@Lilacblossom990]

The best and clearest presentation !

[@sarahlee3100]

Please continue making these videos. Once I learned about your channel, I can't stop watching them to learn more! Very concise and easy to digest diagrams (they are also very cute) Thank you so much

[@SiebertScience]

You're welcome! I plan to keep making them!

[@emersongill8501]

I'm a very visual learner and the way you drew it all out and separated the different processes! thank you for finally helping my brain understand this topic :) If I get an A on my exam today I can thank you!!

[@SiebertScience]

Glad the videos were helpful. Let me know how you did on your exam!

[@AnaMishu]

I always watch your videos before reading a textbook bc most of the time textbook seems very complicated, then I do my quizz assignment with ease

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I watched several videos from other people about this topic, and I was 😵‍💫 until I found yours. Your video is GREAT, and I just subscribed. Thank you !!!

[@GiftVingula-g5d]

This is amazing explanation ever held

[@zygridollero5479]

Thank you so much for doing this! I was having a hard time reading about this topic on my own. It made so much sense :D

[@chrisandarianna1583]

Bro, THAAAAAANK YOU! I was not understanding this until I saw your video.

[@jodifarias9757]

So clear and beautifully illustrated. Thanks

[@Fatma-kl9lp]

You made learning so much fun. Thanks a lot!

[@karl_fischer]

I have a class test in 4 hours and now I am fully confident that I'll ace that! Thank you.

[@hollyweselowski7442]

thorough and helpful, im an NP student and this was SUPER helpful !

[@ddamme05]

I'm not a Bio major but this is probably the best video explaining anything ever. Helps me understand research I'll have to read for my extra-credit assignment. Thanks!

[@SiebertScience]

Best video explaining anything ever??? What a great compliment! I appreciate it!

[@sadraaghanoor]

I would like to thank you for your clear explanation. ❤

[@darianleduc]

Thank you so much! Adding the etymology of the cell and biochem names is super helpful

[@alperbulut1267]

i didnt had a problem with focusing on your lecture. That's rare for me thank you for the video

[@allround8771]

I've been watching a couple of videos on the Immune System and I could easily admit that you're the Phil Jackson of Immunology. Well, Phil Jackson with a touch of DiCaprio (nice fake acting lol). You've mastered the act of transferring knowledge. Thank you!!!

[@SiebertScience]

Hey, my students tell me my acting is improving! But they’re probably just being nice... Thanks for the comment!

[@heatherkrn5200]

This is the most helpful video I have seen on the interaction within the adaptive immune system. Thank you for such a clear explanation

[@chrissvitreoushumour]

awesome explanation. you connected the processes of cell-mediated and humoral immunity really well

[@jo_lenin8990]

Super cool video. Thank you so much. You make it straight forward, interesting and deep at the same time. Best doctor here!

[@stephaniemiller5165]

I Spent a week trying to figure this out and u explained it in a few minutes. You are truly a teacher indeed. Can you couple this with the Mac 1 and two? Omg you are good. I have hope now of passing this section of the exam tomorrow!

[@elle3947]

Took me so long to understand until this short video , so clear :) thanks

[@Jarh9999]

thank you sooooooooo much this clicks so well now

[@SiebertScience]

You're welcome! Glad it helped!

[@mollygrigg7005]

I watched the lymphatic system video and now this … and I want to watch the blood one next. For the very first time I’m finding human body systems fascinating. Never had such a great teacher before. I might have gone into medicine if I had had videos like this in my younger life! Now I’m going to use them to teach my kids!

[@SiebertScience]

Aw, thanks for the kind words! Best of luck with homeschooling anatomy this year!

[@ilaly8347]

You’re literally the best!!! I don’t know why you don’t do biochemistry😭

[@SiebertScience]

I’d love to do biochemistry someday. But this isn’t my job…I do all this stuff in my spare time, so I’m pretty limited in how much content I can make.

[@yhwhspirit]

I thank God for helping me find this channel 🙏🙏 immunology best explanation ❤

[@ajaklual1689]

You are a great teacher 😊😊😊

[@laurenbaron6820]

Thank you so much! Very helpful video. Love the pictures made it much more clear :)

[@SiebertScience]

You're welcome!

[@celinaleal7692]

Love your videos! I'm doing biomed and some concepts I just cant' understand until you explain it. Also, omg I love Cells at Work too!!

[@hamzaha.al-quaid2441]

Really awesome big picture video. Thank you🙏🧬

[@khalidabdulfattahmutwally9286]

Extremely beautiful and beneficial. I love that so much.. please continue

[@pulkitverma8104]

Brother one of the finest video on this topic.....you got my respect 👍🏻🤝🏻

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Bless you! Please continue doing what you're doing! You're an angel

[@파이브-t6w]

I wish you were my biology teacher

[@cbri1621]

Your videos have single handedly taught me all of the systems that we need to know for the MCAT! I never took anatomy as its not required for us and when I started studying I had regrets on not taking it, but man your videos on the immune system, digestive, respiratory, circulatory and kidneys have literally taught me everything!!! Your videos are so well put together and so easy to follow I hope KZbin pays you a million dollars a year for your services :) Question about the immune system: So what is the difference between MHC-II and MHC-I? Are MHC-II's only present on macrophages? Seriously thank you x 1000 and I hope to use your videos throughout medical school once I make it there :)

[@sagaranilkumar8619]

Oh thanku so much for that wonderful class helped me to understand the topic very much... plz keep going and post more videos..

[@ethancraeynest4183]

very clear and specific video, just hoped you would take about the types of interferones and the "component system" too. This would have helped to be even more complete. Maybe talking about the NK-cells too but overall very very good video

[@martashenker]

NK cells are part of the innate immune system, that's why they are not being discussed here

[@rajabumlaluko2897]

I found it more helpful and easy to understand

[@milliecroft1200]

I dont think ive ever commented on a youtube video in my life, but this was so helpful i almost did a backflip out of joy, thanks !!!!!

[@v.2435]

This is so concise, Thank a lot Prof. !!!

[@aggelikinakou_]

oh my god, thank you so much for this video, immunology is driving me crazy

[@marthaschurr7827]

Great video, and such beautiful visuals

[@mohammedshamboul3145]

Thank you You are good medical teacher I watch in youtube

[@evamaryanti800]

Not so convincing coughing, but the lecture was amazinggggg. Thanks!

[@SiebertScience]

So you’re saying I shouldn’t quit KZbin to become an actor??? ;)

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Lol no ...we still need you ​@@SiebertScience

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You have definitely help and educate me so so much with your videos. You are the best with the You analyses and make it look very simple to understand. Thank u so much.

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Thank you so much for such amazing explanation. Definitely gonna nail this topic tomorrow

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Thank you so much that was very helpful

[@32stillgrowingup]

THANK YOU THANK YOU THANK YOU!!

[@jenniferthomas6592]

This was super helpful! Thank you!

[@trinityg8511]

the best video to explain this. I really wanted a clear cut, step by step demonstration and this is incredibly helpful. thankyou!

[@rimikabanerjeesadhu9741]

Explained well......

[@Heh18287]

thanks you for this AMAZING explanation, and you should definitely be an actor😂

[@grrrrr219]

hataraku saibou in the background! It's a good show focusing on body immunology ! 😄

[@SiebertScience]

I was hoping some people would notice that! Great show!

[@BirhanuChalie-d7n]

Fantastic lecture and comments

[@vectorie6195]

Thank you so much

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YOU ARE THE BEST!!!!

[@taylorguarino1555]

Thank you so much for this amazing video

[@kimmagri181]

Very helpful ! Thank you so much :)

[@SiebertScience]

You're welcome!

[@sandyable]

so far your videos have been very helpful:) thank you for making it easier for us. although I didn't believe you were sick :x

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best guide ever!

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When you're taking a 6 week online accelerated A&P 2 class before nursing school starts-- you're freaking out and then you find Siebert Science. I may pass now. THANK YOU. lol

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same lol

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Big help 🎉 thank you!

[@Ahmad_Fawaz]

Can you make vd about the non-specific?

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THANK YOU SO MUCH 🙌🏼🙌🏼🙌🏼🙌🏼🙌🏼

[@teresap8428]

The intelligence of our body

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This is a great video thanks so much for making it

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I like the Cells at Work easter egg.

[@SiebertScience]

Yeah, I just discovered the show last week! So good!

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That is amazing specially the fake cough 😂❤

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100% perfect🤞👏👏clear and understandable ♥️

[@SiebertScience]

Thanks so much!

[@cortneyellyn3233]

Do you have a video on Hypersensitivity Reactions?

[@dejaminsjourney]

Many thanks very good video

[@VennelaReddy-fj3st]

this guy made my life a lot easier

[@victormulenga4690]

wonderful and help tutorial, I like it

[@SiebertScience]

Thanks for the comment!

[@Yo_Thenics]

What about MHC 1 that present the antigen for T cytotoxic?

[@mangajunction8762]

This is good ✨

[@SiebertScience]

Thanks!

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