Svante Pääbo: DNA clues to our inner neanderthal

[@samirkarki192]

Congratulations Dr Paabo. Finally after 10 years your groundbreaking work has been recognized!

[@FlyUnicornsFly]

Dr. Pääbo does amazing work, following the scientific method & seeing where it leads rather than starting out with an agenda that he wants to prove/disprove. A scholar & a gentleman.

[@kenneththomas2032]

It's proof that almost everything new in science, is not proof?

[@sauravraj4694]

Prof Savante received Noble prize this year on 3rd October 2022 for his contribution in the fields of Neanderthal. He is currently adjunct professor at OIST, Okinawa Japan.

[@amandaxin6384]

Congratulations!! Coming back to this talk after this year’s Nobel Prize.

[@DrSimranHatake]

Yesss🎉

[@mariusj8542]

Congrats to this man, got today the Nobel Prize

[@FatLingon]

I would single handedly given Svante a standing ovation for presenting this info.

[@marujob6619]

He just won the Nobel

[@MrBobman360]

How you gonna give an ovation to someone with only one hand?

[@channel-eq6vr]

@@MrBobman360With ironic humor either everything goes untested or nothing goes tested. 😊

[@hypedpotential]

I get so happy when I see how different we all are, yet soooo bloody similar at the same time.

[@stephanieyee9784]

We're all human.

[@alpachino2shae]

Great talk. He could very well win a Nobel Prize one day.

[@AkashKumarPhD]

🤣

[@Patricia-uz2xx]

He did finally :)

[@jasonblack4208]

Off topic, but...that set is gorgeous. I've never seen a Ted Talk with a set like that

[@AB-it3to]

Congratulations, Dr. Paabo on your nobel prize!

[@Maleenabcd]

after 30 years of immense dedication he deserve the nobel price. Congratulations from Srilanka...😍

[@briansmobile1]

12:49 "They realized came from the last .... of the little finger of the pinky on the genome." How would such an extremity survive and not a skull or a pelvis, spine, or some more humanly recognizable bone with more protective mass? It seems unlikely for this to be the case. What other bones survived even if they weren't good candidates for genetic sampling? We share genetic material/code with many animals. It's just such a small sample and outside chance that luck would have to be high.

[@metipallearuna223]

"They realized came from the.. last of the likely culture of DNA sequence of the dentine enamel on the little girl hominin ",very much like our ancestors, as well as of a recent picture of you and me that who have 2.5 percent Neanderthal gene from inside of Africa and 5 percent outside with mixing between the 2. Surprisingly, none is seen to be present in our genes hunting for the DNA samples of the little pinky finger from a Cave in Iceland, in other words overstays in the -D e v o s i n a n genome sequence, since these are all irredundant code created by that time of divergent sequences of DNA in the enamelogen and enamelin protein architecture of the African Americans.

[@joqhernandez]

Indeed, it is absolutely fascinating and definitely a theory that may be supported by some compelling evidece, as we uncover more about the function of the genes and their role in our cognitive development etc. I would love to see further research into this area and hope the progress won't be hampered by political reasons. It is an area of research that could meet resistance.

[@pangao4587]

Congrats to Dr. Pääbo for winning the 2022 Nobel Prize in Physiology or Medicine.

[@TheScienceFoundation]

If we're all Africans because of a recent exile, on what basis are we not all marine animals based on the environment of our much more distant ancestors? Where is the line? Who decided this?

[@Ataturk135]

I hope you win noble prize in 2022 in physiology and medicine

[@TheScienceFoundation]

@marcarmstrong88 People keep missing my point, I wasn't saying that we were fish. I was saying that we were as much fish as we were African (those of us who weren't born in Africa) You can say we're of African descent, but we're not African.

[@guerreiro943]

Congrats on your Nobel Prize Svante Paabo!

[@ee25ankanroy41]

The winner of this year Nobel prize ❤️

[@TheTamriel]

← 2.8% Neanderthal, 0.2% Denisovan, meaning, my ancestors came from the once dry land called Beringia, the today Bering Sea, and before, from Siberia. A long way to go to post here.

[@rick88261]

Ana Surena Vandenberg dos Santos u r just one hot Latina. U bring out the cave man in me😍😍

[@Ppurk]

hello cousin!

[@RakeshDas-dw4ds]

Congratulations Sir for the Noble prize Sir.

[@aryanhs9123]

WHO IS HERE AFTER HE WON NOBEL

[@trevorstieger6762]

true legend and inspiration. thank you

[@swemalamute]

His Swedish accent is awesome

[@herrfriberger5]

@@johnparker7998 He has nothing to do with Finland. Svante was born and raised in Sweden, by a Swedish father (Nobel prize laureate) and an Swedish-Estonian mother (chemist).

[@melinam6855]

I love how he explains, that makes you wonder more, THank u Dr.Paabo

[@aaseevaham]

we are all from sunken continent kumari kandam. we all spoke the same language called tamil and it is mother of african, european language. czechoslovakia is full of tamil language and the meaning of czechoslovakia in tamil is spoken langugage, i am worried how this professor got noble price to 'understand the orgin of human kind'. Thanks. this comment is my perception

[@truthseeker28]

Also note, the neanderthal have been shown to have brains that are 20% larger than modern day humans. They were very intelligent, contrary to popular belief. :D

[@kaleef_sabali_i_am]

Larger brain doesn't mean more intelligence°

[@michaelbrown8949]

A smaller brain is quicker and more efficient. A bigger brain can be the product of disease.

[@neurosynchron]

Congratulations for his Nobel Prize

[@Bushtailedwildcat]

A multiregional hypothesis for the significant presence of human diversity, Milford H. Wolpoff inline for some recognition for his theory. Interesting turnout for the Papua new Guineans at 5%, which in comparison to some African sequences may represent potential for speciation in modern humans.

[@matthiasrodz8182]

Very good Dr. Paabo

[@websnarf]

@moidamir Native North Americans are most closely related to Siberians (roughly where they found the Denosivan finger and tooth). Their genetic separation is by about 15,000 (+- 1,000) years (meaning that 15k years ago they had a common ancestor, probably in North East Asia.)

[@Bushtailedwildcat]

It is thought that Homo sapiens travelled from Djibouti or Eritrea around 90 thousand years ago into Yemen and continued to spread due to changes in climate at that time. Humans as indifferent to life will produce more young than is sustainable in their present environment. To find food they wander to ‘greener land’. As a result the expansion of modern man can be drawn to map as other extinct migrations before.

[@bourbakis]

Fascinating stuff! The same DNA study should be done on "Peking Man" as well.

[@stephanieyee9784]

That would be very interesting.

[@websnarf]

So awesome. Is too bad he had no comment about the recent analysis of the HLA immune system genetic overlap with the Denisovans. That seems to have a lot of implications for exactly how sharp the boundary is for the Denisovan mixing.

[@marujob6619]

🤝🏾

[@carlosluis1970]

thank you so much sir, for your dedication to the development of science and knowledge.... congrats for the prize

[@websnarf]

@interstellarwonder : Chimp DNA itself is not older than humans -- they are contemporary animals with us. However the common elements of the Chimps and humans is obviously older (dating to 5-7 million years old) than the common elements among humans (and Neanderthal and Denisovans) themselves (maybe up to 800 thousand years ago, according to this talk).

[@kartikad5612]

Congratulations 🎉

[@medic.t]

HELLO PEOPLE FROM DR. TU's PERIOD 5 BIO CLASS DOING THE NEANDERTHAL PRELAB!!!

[@carmenbenitez7134]

Ben Ho eyyy ben....WAIT IF UVE DONE THE PRELAB WHY WONT YOU SEND IT TO ME

[@Seojunnies]

Ben Ho LOL BENNN

[@Seojunnies]

Carmen Benitez what if tu sees this LOL

[@mohammedsarker5756]

Ben Ho Ben, you suck. :)

[@ThePie4DaWin]

Ben Ho I'm just here last minute. don't mind me

[@NeedsEvidence]

Superb research. Thank you!

[@Bushtailedwildcat]

They represent chromosomes or rather an individual chromatid (1/2 chromosome) which stores DNA during cell division; two 'arms' and the centromere center. The rest of the time DNA exists as a dissolved mass which isn't iconic enough to identify with.

[@metipallearuna223]

It being a case of 1/2 unscheduled DNA synthesis which during cell division ,divides Centromere into Hominin homing our present gene sequences as ir-redundant ,common to our extinct ancestors.

[@fringeelements]

I hate it when people say "we are all africans". Sure it's true, but you can also say "we are all earthlings". It's not particularly relevant, because when someone says "that person looks african", they're not talking about a blonde-haired fair skinned Swede. Saying "we are all africans" is just a PC slogan.

[@GoldenPAM]

Congratulations Dr Paabo.

[@TodayUntilTomorrow]

In some ways I feel compassion for Dr. Paabo. He is going to have to spend the rest of his life dancing around what his data is really saying.

[@stephanieyee9784]

As time has passed and more discoveries have been made, by Dr Paabo and other geneticists, we have only come to learn more about our ancient ancestors and the mixes thst occurred as a result of the meetings. Whether any of the meetings and matings were consensual or forced is way beyond anything we could hypothesise but they did happen. Genetics is a fascinating science and new discoveries are made all the time.

[@Scriabin_fan]

And what is exactly do you think his data is really saying? And how tf would you know what it's saying?

[@TruthSerum101]

@Schneboll Your condolences are appreciated. In the end, relevance is relative. We all have our agendas and perspectives.

[@gulllars]

@LithiumLogica One way to hope to influence future TED uploads could be to PM the "TEDtalksDirector" channel/user asking for volume adjustment on intro/outro. If enough of us does that, maybe the guy/people uploading will notice when there's 100-100+ messages in the inbox all saying "ADJUST THE VOLUME" in the title. Just my thoughts.

[@raozubairkhaliq9092]

Congrats on winning the Nobel Prize, Sir.

[@MrJbreezy21]

pay attention, he was saying that Neanderthals never went to Africa, it was migrating Africans that met them

[@marujob6619]

Congrats Sir

[@funnyguylol69]

Amazing research.

[@TheScienceFoundation]

@dreapster His point in calling us Africans was that we were recently expelled from Africa

[@manus6112]

KZbin really knows how to suggest things ,.

[@StrivedDevotion]

I don't want to sound like a person that follows reason as a main criterion to addressing issues but how many people must complain about the intro-outro volume on every single TED video; if you really want to fix the problem, adjust the volume before hand KNOWING it's probably going to be loud. It doesn't take someone who watches TED videos regularly to know this.

[@poorsoul7000]

Congratulations doctor.....

[@dookiecheez]

@batfly It's not how much is "held back", it's how much you're simply not aware of. Some of it is easily accessible on the internet, while others merely require a subscription to a scientific periodical. 1 example of the aging process that's understood is the degradation of telomere.

[@richardevppro3980]

Did the Denisovans move early in a time before we mixed so they would be isolated on their on DNA?

[@TheThomaswastaken]

If you have a basic understanding of Anthropology you can skip to 5:00.

[@GraeHall]

@VitriolicAC My mother was born in Finland, and her family goes back 1-2k years there. My father born in Australia, and goes back to the first fleet down his fathers side, and denmark on his mothers side. I am a finnish australan citizen - and the danish thing, I'll look in to it next time in in scandinavia. I don't feel divided, I feel diverse. Growing up experiencing several unique cultures in the home, being bilingual. Kicks ass. People who make it a drama are attention seekers.

[@stephanieyee9784]

I'm a mixed Aussie too. 36% Chinese, 20% Welsh, 28% English, 12% each Scotland and Ireland and a dash of Swedish. Father Chinese and Irish. Mother Welsh, English, Irish and Scottish. Maybe her Scandi blood is from her Yorkshire ancestors? Whatever, we're Australian. ☮❤🦘🇦🇺

[@VenkatramananSrinivasanjd19]

every one is from the same place , and the cause we split from that place to different place is for what? just to multiply our specious there might be some reason behind it , cause the people from ancient are not fool , there might be some reason behind it while they have the change of place .

[@xapemanx]

first time I took notes on a tedtalk.

[@duckmanjoel]

I know a nurse with blond hair and blue eyes who immigrated from Africa. She is African. I have a friend from Nigeria who told me he laughs when American blacks say they are African Americans because he says "I am African". Almost all American blacks have "other" blood. The USA is the opposite of most other countries where a little African and you are black. Most countries a little Caucasian and you are white. Obama would be white. GENETICALLY, we are all Africans.

[@thewordofgod2010]

The reason we mixed with Neanderthals is very simple. Neanderthals were 100% human otherwise there could be no fertile offspring. This works the same in the entire animals kingdom, and has been understood for centuries.

[@DiamondMind]

So basically we are all much more similiar than we are different.

[@carlosluis1970]

exactly

[@ignisdesuper]

this man is someone i wish to study UNDER

[@atharvadeshmukh2454]

Nobel prize winner

[@GraeHall]

@ranasingh: if the style of the presenter is what you find exciting, or lacking in excitement, when there's such exciting new information being presented here by them, allow me to suggest: Entertainment Tonight, and American Idol.

[@kaktoip9142]

Congrate for the nobel prize!

[@SkyGuySunny]

@TheScienceFoundation I think the line in this case is the species Homo sapiens sapiens. We are all of this species (sub-species in fact) and it is an African species.

[@marcarmstrong88]

@interstellarwonder in what way is it older? its far more diverse yea?

[@neurel111]

He made a lot of inferences but I will agree that they are reasonable given the evidence at hand, good science.

[@AsmeretSomura]

No. It's not simply a linguistic pun. Paabo is showcasing his research behind the genetic connections between Africa and the general population. The fact that the human species stems from the African continent specifically has been proven by archeologist findings of humanoid species skeletal remains. These discoveries have been on-going for decades now & I still can't fathom the thought as to how you can make a statement that tries to undermine the scientific evidence that proves/supports

[@NorthLoftier]

Fascinating.

[@Yaalah]

@StrivedDevotion I just turn the volume off until the video starts, then I click to 0:15, which is when the intro music ends. The intro is the most annoying thing I listen on any given day.

[@jonaskong8123]

1:56 Both branches for humans are labelled "Human 1"

[@websnarf]

@Eleandorwins : Well hair color, height, skin color, etc are all genetic factors. There has to be *some* difference.

[@moidamir]

Interesting, although there is no mention of the native-americans. I am curious to know if the have any significant differences with the eurasians and/or africans.

[@h.o.p.efoundation8908]

cheikh anta diop & chancellor williams stated this 40 yrs ago LOL

[@farvision]

@LithiumLogica I agree with you 100% about the idioticaly loud introduction! I've written to them more than a year ago about this and they ignored it. Folks, keep talking about it if it bothers you!

[@TruthSerum101]

@Schneboll The point is that we've both known teachers. There.

[@sogghartha]

@batfly That knowledge isn't hidden. You can find information if you go look for it, but it would go right over your head. You'd have to be a biologist or gerontologist to understand it all. Secondly, genetics is far more complex than you might think. It's not a blueprint, but more like a set of instructions, like a programmer's code. So unraveling and decoding it is quite complex.

[@reinereiner]

Da ist es schon interessant und spannend, auf welches Ergebnis man beim Danuvios Guggemosis kommt. Radiästhetisch deckt sich vieles mit meinen Ergebnissen...

[@imnpp1503]

Congratulations sir,,,,,,, 💐💐💐💐

[@captaintarot]

노벨상 수상 축하드립니다!! 😄

[@TheScienceFoundation]

@SkyGuySunny It originated in Africa but saying we're African because our ancestors were African holds no water. You can say we're of African descent, but we're not African.

[@a575981735977018]

@OpiatedBliss ..or youinherited the gene to be bored by this... It was not boring to me, only very slow and clear, which is good to avoid misunderstandings...

[@panafricandesignsandapparel]

11:50

[@tonyjeunesse9607]

La tsvt 4 on est la ou pas

[@matthiasrodz8182]

OUAIS OUAIS OUAIS

[@xinlo]

@christo930 Oh alright just making sure. I've found that a lot of people, even the relatively well educated, don't always understand this nuance.

[@mauiuam]

its NOT PC slogan, if you compare how long a group of people has been living someplace where they ORIGINATED vs how long they been living outside of their original starting point then depending on that ratio would clarify where they are from. If I say, "I was born in Canada and lived there for 30 years but I'm currently living in China for about 6 years" that suddenly doesn't make you not More Chinese Than Canadian anymore.

[@infinitel8p]

предок дробыша. спасибо за замечательную лекцию. интересно, когда наш дробышевский получит нобелевку

[@TheScienceFoundation]

@marcarmstrong88 Actually my point was you can't say we're African any more than you can say we're fish.

[@Ahmadaliexplore]

Congratulations

[@RobertBainesSITKA]

@TastyPie95 Oh, I see. I had the video playing while doing other things, so I must have missed that part. Thank you.

[@MoOtJeMan]

@Quintinohthree Practically, it will change. I'm sure in 20 or 40 years we can recreate the neanderthals. if it should be done is another thing. yes, it can show a perspective of our past with these people but what are the risks?

[@TheScienceFoundation]

@KhamusSolo That was my point. Classification such as 'we are all Africans' is arbitrary and meaningless.

[@DorakoftheHillPeople]

@TruthSerum101 Indeed. This thread continues to make that rather apparent.

[@advers1078]

@NiborYecnuad That's an interesting hypothesis after all they could have, due to natural selection, came to the same adaptation as Neanderthals and like you said with influenced from the environment being the driving factor, I think they need to complete the sample of Neanderthal genome, as stated in the video only 55% of Neanderthal genome has been sequenced, with a more complete sample they could find out just how much we share and that would open up more interesting routes of investigation.

[@47f0]

Translation. Modern humans will screw just about anything that moves. Thank you, but having observed the singles bar scene, I was already pretty convinced of that hypothesis. It's nice to have genetic confirmation, though.

[@bubstacrini8851]

And somethings that don't move

[@durstwurst]

and btw. where did you get this 15 point gap number from?

[@Zuriki09]

@dragonvegeta Star Wars was set a long time ago, so surely we're in the post-star wars age?

[@coffeefirst6613]

Interessantes video, es is sehr schwer Menschen von Affen zu unterscheiden, sie sind nicht gleich aber teilen viele Gemensamkeiten in gentic, es ist genauso wie bei Menschen und Schweine