The ACTUAL Cause of Artery Plaque - ApoB? LDL? Cholesterol?

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Dr. Anthony Jay

Dr. Anthony Jay

Күн бұрын

Welcome! I have a PhD in Biochemistry from Boston University School of Medicine. Today, I discuss the science surrounding
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#heartdisease #apob #cholesterol

Пікірлер: 871
@gehallak660
@gehallak660 7 ай бұрын
"ApoB is the new way of saying your total cholesterol is too high, without saying your total cholesterol is too high". Thank you soooo much for clarifying. I always felt it was pompous and not significant. First time I listen to you and I already like your content.
@lazarus8453
@lazarus8453 7 ай бұрын
Bro you guys are in horrible diet cult. Scientific evidence is very clear that high ApoB levels causes cardiovascular diseases.
@wocket42
@wocket42 6 ай бұрын
TC is LDL plus HDL. Apo b is not HDL. The paper he quoted also talked about apo b being like LDL-C, not TC.
@TheCompleteGuitarist
@TheCompleteGuitarist 5 ай бұрын
@@wocket42 From a famous online encylopedia. Basically ApoB is primary protein that binds lipoproteins VLDL, IDL, LDL and also contributes to HDL. This line of lipoproteins is actually how they transition from one to the next.
@hsiao-suhsu9613
@hsiao-suhsu9613 5 ай бұрын
@@wocket42very kind comment, only expressed the fact without personal attack. You have credibility!
@christaft3506
@christaft3506 5 ай бұрын
How do you actually get all cardiologist to agree with you
@rickknowles9620
@rickknowles9620 7 ай бұрын
Its good to see more and more doctors coming out with the real information. Congratulations.
@ellenstromeyer6949
@ellenstromeyer6949 6 ай бұрын
Finally someone who agrees with me. I am so tired of arguing with doctors. How refreshing!
@broccoli-dev
@broccoli-dev 4 ай бұрын
This. It's important to always seek out people who agree with you. Never listen to anyone who disagrees with you. This is how we progress.
@tonycollyweston6182
@tonycollyweston6182 3 ай бұрын
​@@broccoli-devvery funny
@margaretaskew8220
@margaretaskew8220 Ай бұрын
When I told the consultant at the lipid clinic I didn’t believe cholesterol was the cause of plaques but sugar then the cholesterol comes to help. He laughed at me !!
@lindaloranger2998
@lindaloranger2998 25 күн бұрын
@@margaretaskew8220sad state of affairs
@Kjuken69
@Kjuken69 7 күн бұрын
It's not about agreeing it's about fact , fact and logical thinking, how can cholesterol be damaging, the body makes something who damages it self? Please don't be so stupid
@saratonnan
@saratonnan 5 ай бұрын
Finally! A doc who explains things in straight forward, understandable terms. I'm a retired RN and have been on a quest to get solid answers to my questions about my meds & side effects, plus healthiest diet choices. Long story short, you have confirmed in simple terms that the studies I've been wading through are correct. In recent months, I've quit the statins and cleaned out all the processed foods from my house. I got off the vegan diet & switched to a whole foods, low carbohydrates, ketogenic diet. Also quit the antacid I've been on for years that was likely interfering with nutient absorption. My god, I feel so much better & my brain fog has cleared. This is my new favorite go-to channel for health information! Thanks, so much, Dr. Jay!
@ShoppingEmail-dr1fs
@ShoppingEmail-dr1fs Ай бұрын
good for you!!!! my vegan friends eat so much rubbish and are fat and anemic.
@charleeghee7195
@charleeghee7195 29 күн бұрын
Good for you in making all those changes! I too agree with you on what a great channel this is.
@stevegillette9800
@stevegillette9800 6 ай бұрын
My doc tried to put me on statins because of high cholesterol, even though I had high hdl & low triglycerides , ratio 0.6 & a recent angiogram & ultrasound confirmed no plague build-up in coronary arteries. I am 62 , 1.84m, 70kg,type 1 diabetic, do 10 hours cycling/gym every week & have been on a keto diet for 3 years together with intermittent fasting ,20/4. And this was after he advised me that Type 2 diabetes could not be reversed!! I almost reported him to the GMC ! Keep up the good work.
@ssa8479
@ssa8479 4 ай бұрын
I went through that with my doc as well, had to tell him to note that patient had declined statins. I'm 65, BMI of 19 (135 lb / 61kg), total cholesterol 553, LDL 474 (large or Pattern A), HDL 86, trig 56, VLDL too low to be measured, Lp(a) 18, HS-CRP 0.95 and insulin of 6.7. All he says is "your total cholesterol is too high!" and "your LDL is too high!" and "low fat, low salt, lots of fruits of vegetables and very little meat."
@domkukuljica7201
@domkukuljica7201 3 ай бұрын
Carnivore diet reverses Type 2
@dwights1464
@dwights1464 Ай бұрын
Your insulin is on the high side which is probably what's keeping your blood glucose in check.​@@ssa8479
@Casey-rr7th
@Casey-rr7th 7 ай бұрын
Refreshingly straightforward and well-informed content. This is one of the best videos I’ve seen on this subject matter. Thank you for helping us navigate what can be very confusing and often contradictory information on cholesterol et al.
@jimmcmahon7561
@jimmcmahon7561 7 ай бұрын
Had to have a stent in 5 years ago. They put me on an 80 mg huge daily statin. Did some homework. I am PROUD to say that my total cholesterol is UP to 304. Tryglcerides are 63, fasting glucose 79, fasting insulin 3.3, 13% body fat, great ratios ...5'7', 140 lbs, 60 years old.I quit the 80mg and take a 10mg statin every three days bc I heard it can help solidify any soft plaque and help prevent it from rupture/clot/heart attack. Great video Dr.J
@elinino5275
@elinino5275 7 ай бұрын
Did you takes the 80mg statin for 5 years?😮
@jimmcmahon7561
@jimmcmahon7561 7 ай бұрын
I quit the 80mg after 3 months. Statins are getting more and more bad press -- thank God.@@elinino5275
@boguslav9502
@boguslav9502 7 ай бұрын
No idea about solidifying it considering the main reason its non solid is because of inflammation locally in the first place. Statins have serious side effects so considering getting your coronary arteries checked to see if the stent and statin is even necessary or if you are free from needs for meds.
@davidiglesias9549
@davidiglesias9549 7 ай бұрын
You will be getting another Stent with that cholesterol level
@jimmcmahon7561
@jimmcmahon7561 7 ай бұрын
Plenty of studies showing that people with low LDL are not less likely to have a heart attack and that those with high cholesterol and low triglycerides live to a ripe old age.@@davidiglesias9549
@rakghana
@rakghana 7 ай бұрын
Started the carnivore diet and all of a sudden life is worth living.
@CandyGirl44
@CandyGirl44 6 ай бұрын
Carnivore diet. Necrovores are hilarious in their ignorance 🤣🤣🤣
@RogerEriksen-l6h
@RogerEriksen-l6h 6 ай бұрын
@@CandyGirl44 yes, they ignore plants. which is a wise thing
@Unsensitive
@Unsensitive 6 ай бұрын
Honestly, both sides are biased and crazy. Carnivore works. High fat works if you eat the right fats. So does high carb if you eat the right types. For example, a high starch diet,
@BarryAnderson
@BarryAnderson 6 ай бұрын
Carnivore mixed with nitric oxide rich vegetables with intermittent fasting is KEY to the whole issue of heart disease rates.
@rebeccacarraway480
@rebeccacarraway480 6 ай бұрын
@@Unsensitivewhat carbs are good for you?
@midwestribeye7820
@midwestribeye7820 7 ай бұрын
You are one of the only doctors I trust.
@jarichards99utube
@jarichards99utube 7 ай бұрын
Looks like I just found a New Doctor to subscribe to who is BOTH Knowledgable And SANE...!!! A Great and RARE Combination in our Society 😊 👍 -70SomethingGuy
@josieb3238
@josieb3238 7 ай бұрын
I am so glad to find you. This is great information and I feel crazy when my doctor pushes statins. I have a bit of arterial calcification and I hope I can stabilize it with a lchf diet. I’m 75. Good to meet you.
@SaxonSuccess
@SaxonSuccess 6 ай бұрын
@@willnitschke Less than a lot of.
@kaceeboxers3580
@kaceeboxers3580 5 ай бұрын
Your video showed up on my feed, probably because of the many health related channels I listen to. Your information is so refreshing to hear and wish more doctors would research beyond big pharma training in med school. ‘Diagnosis an issue, refer to the pharmacology books for an answer’. Instead of researching diet, nutrient deficiencies and lifestyle factors leading to most diseases. Looking forward to hearing more of your videos.
@randomthoughtstoday
@randomthoughtstoday 4 ай бұрын
God Bless you Dr. Jay. We appreciate the truth on youtube. Rare nowadays!
@rhondaroles1633
@rhondaroles1633 6 ай бұрын
I'm so happy I stumbled on your channel!! Finally a REAL honest and educated doctor confirming my thoughts for years!!!
@frankd1682
@frankd1682 6 ай бұрын
It is difficult to believe anyone. The only sensible thing to do is eat minimally processed foods, a balanced diet, and stay as active or physically fit as you can and let genetics fall where they may.
@mugflub
@mugflub 6 күн бұрын
And take statins if you believe the people who say they're helpful... or don't take them if you don't believe them. XD
@thomasowens5824
@thomasowens5824 Күн бұрын
Never trust a vegan doctor. Cholesterol has no association with heart disease......its not an argument anymore but pharma wants you to take tablets, processed food companys are invested in pharma.
@SeaStarGazer1111
@SeaStarGazer1111 6 ай бұрын
THANK YOU!! An educated consumer/patient is in charge of their own destiny. My GP wanted to put me on a statin bc my LDL is "high" (125) and Tot Chol was 201 at the time. I declined. I've had 2 CCTA's and both ZERO blockages! I eat a little bit of everything.
@dalywildkat
@dalywildkat 6 ай бұрын
What's the ccta's
@rebeccacarraway480
@rebeccacarraway480 6 ай бұрын
@@dalywildkata scan to see the calcium in arteries
@SeaStarGazer1111
@SeaStarGazer1111 6 ай бұрын
@@dalywildkat Coronary computed tomography angiography
@dalywildkat
@dalywildkat 6 ай бұрын
@@SeaStarGazer1111 what's the difference between that one and the CAC test ?
@SeaStarGazer1111
@SeaStarGazer1111 6 ай бұрын
@@dalywildkat One is an angiography with contrast that lets you see the actual blockages. The other not sure, might be just a calcium score test. Google would probably have the answer!
@johntatman9168
@johntatman9168 7 ай бұрын
Just found your video and really appreciate what you say. New follower here.
@markbodine9298
@markbodine9298 6 ай бұрын
Great vid, doc! I’m a 69yo ex- rugby player (18 yrs) and, before that, wrestled for 12 years. My CAC score is 1200. My dad died of an MI at 42. But I told a guy at the gym just recently that inflammation is the root cause of not only cardiovascular disease, but also the majority of chronic and degenerative diseases that are prevalent in the ‘modern’ world. Nice job, PLEASE keep up the good fight!
@the_astro_garden
@the_astro_garden 5 ай бұрын
Thanks for the honesty and for your expertise and time.
@1g1d1w
@1g1d1w 6 ай бұрын
You have become my favorite you tube Dr.
@markoneil5279
@markoneil5279 5 ай бұрын
Anthony is exactly correct on the APO B scam. Anyone with high LDL has high APO B; anyone with high APO B has high LDL. This is a scam. They are trying to convey that they have moved on from the LDL focus, while they are just trying to extend the LDL focus.
@abbiec6057
@abbiec6057 7 ай бұрын
Oh thank you so much! As a practitioner following this game, this is huge for me to see more and more of the facts pointing away from ApoB, and toward inflammation (what about iron/copper? That’s another interesting set of factors affecting inflammation, isn’t it?) Thank you! Oh, and you are awesome. 🙏 Let’s see the science-speak on the CT-angiogram. ❤️
@orlandosanchez3605
@orlandosanchez3605 3 ай бұрын
THIS HAS BEEN ENLIGHTENING. I WILL DIG THOSE STUDIES OUT
@pmccord9
@pmccord9 6 ай бұрын
Thanks. Because I run on ketones, my ApoB is high, 116. Today, my internist tried to use that to warn me off my high fat (low carb) diet because it might cause my heart disease to worsen. He thought he had a point. My calcium score had come in at 1908 a few years ago, so a fair amount of disease (and he wanted me on PCSK9 Inhibitors: I said no). Anyway, from your video, I knew that the ApoB just means "high cholesterol," and my research showed it helps unlock blood fats so that cells can use them, either to fight inflammation and disease, or to use as fuel. I'm the latter: I metabolise them. I showed him that my HS CRP is 0.6, so I have very low inflammation. If the ApoB was marking cholesterol used to fight inflammation, my HS CRP would have reflected the fire in my endothelium, and my doc would have a point. But, no. I also had a new calcium score, 1394, down 500 points (not supposed to happen), and my carotid is also less congested than four years ago (when I started low carb/carnivore). I'm apparently fixing "permanent and debilitating heart disease." And not taking a poison (statin) to do it.
@godblessusall7696
@godblessusall7696 4 ай бұрын
Thank you so VERY much for posting your ApoB and CAC scores! Very interesting! How does your doctor explain the new, lower numbers?
@pmccord9
@pmccord9 4 ай бұрын
@@godblessusall7696 My cardiologist pointedly ignored the change. My internist reports two other patients with similar results.
@Milpower
@Milpower 4 ай бұрын
Statins are shown to reduce the "bad" areas by roughly .3%. In other words, nothing.
@maxwatermeyer4406
@maxwatermeyer4406 2 ай бұрын
Thanks for posting your results and your regression your plaque…its one thing to hear people got an 0 calcium score but its even more remarkable when people with current damage reverses that score because it does give others hope and motivation.
@qkcmnt1242
@qkcmnt1242 6 ай бұрын
I am SO glad that the algorithm sent THIS video to my feed. You have a new subscriber in ME. It is RARE to see doctors act like actuaries, and THAT is what I see in this pathologist, or dead person surgeon. I am blown AWAY by his astonishing GRIP on information statistics, with a touch of humor. 😊 Wow 😳, just WOW. 🎉 Thanks.
@dpasek1
@dpasek1 5 ай бұрын
A bigger problem than oxidized cholesterol and, btw, oxidized PUFAs, is glycated ApoB, which leads to the formation of sdLDL. It is *not* ApoB itself that is the problem, but the glycation of this protein caused by chronically elevated blood glucose. This is part of the connection between diabetes and elevated CVD risk. What they are really trying to do by reducing ApoB is to reduce the LDL particle count, which can be accomplished by reducing sdLDL and shifting "pattern B" toward "pattern A".
@lloydhlavac6807
@lloydhlavac6807 7 ай бұрын
This popped up on my recommended list, and I didn't know what to expect. I have to say I am pleasantly surprised by the content of this video. 👍
@KatieZeldin
@KatieZeldin 7 ай бұрын
Same here😍
@friends4u0706
@friends4u0706 6 ай бұрын
SAME HERE
@FatherGorgony
@FatherGorgony 21 күн бұрын
Thank you. Finally, I met a doctor who distinguishes cause from effect. I will be happy to study your other videos:-)
@karenmcnamara405
@karenmcnamara405 5 ай бұрын
Thank you for this. I appreciate you speaking the truth about cholesterol.
@bobknob8261
@bobknob8261 6 ай бұрын
Love the fact that you think outside the box
@hektor6766
@hektor6766 6 ай бұрын
Surprised this guy never hit my algorithm before.
@seanconnolly2179
@seanconnolly2179 6 ай бұрын
Me too
@Thewellshomestead
@Thewellshomestead 6 ай бұрын
Same!
@neilfrasersmith
@neilfrasersmith 6 ай бұрын
Me too, probably downgraded by the algorithm as it goes against the narrative.
@arnoldfrackenmeyer8157
@arnoldfrackenmeyer8157 7 ай бұрын
I like this Guy! He is sharp and alert. I'm gonna email him.
@robwozniak9912
@robwozniak9912 5 ай бұрын
Thank you Dr. Jay! I'm 52 and have been on an anti-inflammatory diet with IMF for a few years now. I've lost 50 pounds and have never felt healthier. However, my LDL and ApoB have gone up and my doctor wants me to get on a statin. Thus far I've refused but wasn't so sure when he started talking about ApoB. This clarifies things tremendously.
@olekirkelund7755
@olekirkelund7755 6 ай бұрын
That was really a great and clarifying presentation. Thanks a lot!
@dranthonyjay
@dranthonyjay 6 ай бұрын
Glad it was helpful!
@bobdec6665
@bobdec6665 7 ай бұрын
SUGAR. get rid of it from your diet
@AliceFarmer-bg4dw
@AliceFarmer-bg4dw 7 ай бұрын
Bread, cereal, grains, rice, pasta, beans and legumes are high in simple carbohydrates which turn into glucose.
@ph69jbl
@ph69jbl 7 ай бұрын
The real culprits
@Miraak1868
@Miraak1868 7 ай бұрын
Don't forget seed oils, the other poison.
@JWB671
@JWB671 7 ай бұрын
Your liver makes glucose as you sleep you realize…
@ChuckMcC
@ChuckMcC 7 ай бұрын
Yes... Just enough for bodily functions. Adding excess sugar causes glycation of the endothelium of your arteries IE: inflammation...
@BiohackerNYC
@BiohackerNYC 7 ай бұрын
Excellent! Thank you Dr . Jay
@keithhaken172
@keithhaken172 5 ай бұрын
Very good video doc. I’ve been thinking everything you just mentioned. I’m happy a smart guy confirmed it. ✊
@dranthonyjay
@dranthonyjay 5 ай бұрын
Glad to hear it
@_sal.garfi_
@_sal.garfi_ Күн бұрын
my total cholesterol is 205 - My Dr. today said I need to reduce fats, cheeses, and meats. I start my day with a shot of Extra virgin olive oil(good source), drink RYZE mushroom coffee daily, eat oatmeal everyday, chia seeds, 4 eggs a day, steak, turkey, chicken, healthy pastas, rice, avocados, etc... I couldn't eat a healthier diet if I tried. I train 5 days a week strength training...extremely frustrating but this video makes me feel better for sure. My doctors are from the old school too, not willing to learn regarding cholesterol. Not sure what I should do, but I think I am in a good place after watching this video.
@delianestor4278
@delianestor4278 7 ай бұрын
Excellent. Straight to the point and I actually could understand it. Thank you
@dranthonyjay
@dranthonyjay 7 ай бұрын
👍
@BillDallmeyer
@BillDallmeyer 6 ай бұрын
Can you do a video describing the "if this, then that" of blood lipid tests? As in, if you have high total or LDL cholesterol, get a CAC scan to determine if you have plaque. And if you have plaque- then? Or if not then what? Don't worry? Change diet to get under 280? Thanks for all the great info!
@sashidemedia
@sashidemedia 6 ай бұрын
Man, you've pretty much summarized everything so well in this one video. Everyone on KZbin is selling something and pushing an agenda. Your open ness comes thru . Subbed
@wocket42
@wocket42 6 ай бұрын
If IT admins worked like doctors, they would tell people with apple computers to install Windows patches, because research shows this helps with most computer problems.
@dranthonyjay
@dranthonyjay 6 ай бұрын
nailed it
@christyb7590
@christyb7590 6 ай бұрын
I had a heart attack 4 years ago at 48yrs old. 3 stents right side. I was is good physical health otger than I smoked. So I stopped. Then they gave me statins and blood thinners and a year later I had gained pounds and Type 2. Know that pre heart attack I never was diagnosed with Type 2 and regularly went to my doctor. I did have a lot of stress, physical and mental. I switched to a clean Keto. My cholesterol went up but everything else went down. A1C 7.4 to 5.3. I stopped taking the statins. I believe they caused the carnage after my heart attack. I eat a clean Keto. Feel better than ever
@waynegrayson4530
@waynegrayson4530 6 ай бұрын
I would say 100% the statins caused a lot of your problems including the type 2 as I've seen several videos about that where studies expose the risks. My father was on statins since around his late 50's until he died last year at 83. By the time he was 70 his muscles had seized up, he could hardly walk, and he developed type 2 by the time he was in his 60's which just got worse and worse. I tried to get him off them but he always had total faith in the medical industry.
@rebeccacarraway480
@rebeccacarraway480 6 ай бұрын
How bad did your heart doc spaz out?? 😂 Keep up the good work.
@qkcmnt1242
@qkcmnt1242 6 ай бұрын
Thanks for your testimony. 👍🏻
@christyb7590
@christyb7590 6 ай бұрын
@@rebeccacarraway480 Complete spaz out. I have learned to do my own research and be prepared.
@rebeccacarraway480
@rebeccacarraway480 6 ай бұрын
@@christyb7590 I bet!! Good wishes for your continued health!
@BeauCS
@BeauCS 6 ай бұрын
What is your take on the Ference et al large Mendelian randomization study showing LDL as such a distinct risk factor? Based on what I’ve heard from Attia, that is the study which most concerned him. Also thanks for the great video.
@richardayala4356
@richardayala4356 5 ай бұрын
Liked and subscribed! I follow a number of medical doctors who state the same as you. Good information.
@ytubechannel997
@ytubechannel997 5 ай бұрын
Awesome information. Can you do a video on ways that one can lower arterial inflammation using methods such as intermittent fasting?
@misterbaleize
@misterbaleize 7 ай бұрын
What a fantastic and most refreshing presentation; thank you. I am a LMHR and have no concerns in carrying high quantities of the "other good cholesterol" - LDL - in my blood.
@c.a.g.3130
@c.a.g.3130 6 ай бұрын
Dittos.
@selenataylor6959
@selenataylor6959 6 ай бұрын
Ditto
@4spbiz
@4spbiz 6 ай бұрын
Abbreviations are so annoying. They assume everybody knows what it means.
@c.a.g.3130
@c.a.g.3130 6 ай бұрын
Lean Mass Hyper Responder@@4spbiz
@richardedwards6692
@richardedwards6692 6 ай бұрын
​@@4spbizLMHR = Lean Mass Hyper Responder.
@kersplatte
@kersplatte 6 ай бұрын
I appreciate you calling out that peer review is politicized
@ilanbenshoshan8719
@ilanbenshoshan8719 7 ай бұрын
Great video. I like this guy. I listen to Peter Attia but I have a weird vibe that he may work with the pharmaceutical company. Anthony seems more like a guy who knows the science behind it all.
@beepbeepnj2658
@beepbeepnj2658 7 ай бұрын
ApoB is about the same as LDL it's just to sell more tests. "Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio. High Lp(a) is in your genetics to make you live a long healthy life but low Lipoprotein(a) is bad news. 2012 article title: Low Lipoprotein(a) Concentration Is Associated with Cancer and All-Cause Deaths: A Population-Based Cohort Study (The JMS Cohort Study) The Lp(a) levels were inversely correlated with the CIMT in this population, suggesting that subjects with a low Lp(a) level may have a predisposition to carotid atherosclerosis. This finding was preliminary and should be investigated further in larger studies and in additional settings. 2012 article title, CIMT thickness in asymptomatic subjects with low Lipoprotein(a) levels.
@thebrocheckclub1777
@thebrocheckclub1777 6 ай бұрын
We need mucher longer term studies to understand the effect of high fat and how it damages the endothelium
@lanesebringmd802
@lanesebringmd802 6 ай бұрын
Loved your podcast. I appreciate what you’re doing. I’m actually the first MD in America to base their practice off the Paleo diet starting in 1997 after hearing a lecture by doctor, Lauren Cordain a few months before his published paper came out. I am now carnivore for about 11 months and have been against use of Statin drugs for over 25years. I heard Peter Peter Attia, speak at the A4 lecture several years ago, and was unimpressed. He’s a late comer with poor understanding how things work, but has promoted himself as an expert. Thanks for calling him out.
@dranthonyjay
@dranthonyjay 6 ай бұрын
wow, 1997 is legit. Robb Wolf is a freind of mine
@lanesebringmd802
@lanesebringmd802 5 ай бұрын
@@dranthonyjay A mutual friend. Tell him I said hello. Thanks for responding. Nice chat. Keep up the good work.
@WideAwakeHuman
@WideAwakeHuman 4 ай бұрын
I’ve had the same impression of Attia… too arrogant to ever question his own assumptions until it shows up in 100 RCTs which means he’s always 5-15yrs behind the best data.
@bwnco
@bwnco 4 ай бұрын
Thanks Doc for responding to this video. Those of us out here in normal world non docs are screaming for real truth. Obvious after a certain virus was out that pharmies more interested in profit then health. Pharmies is huge business. Statins numer uno! We go to the doctor, they say, take this. Take that. And we're told they're experts. So it really tweaks her mind. Who do you believe? Then you go to another doctor and they said, no, this is **** So it's great to see someone like Dr J put up scientific reason why and then have a doctor confirm it. We really appreciate it. You have no idea how. hard it is for those of us who want good health, good diet Do you eat vegetables? Do you not eat vegetables? Do you go to Carni? Do you not eat carni and hear doctors are supposed to be experts So it's tough for us. So thanks for the confirmation, think a few more are coming out! LOL 1997 ya wow!!!!
@margaretfoley1247
@margaretfoley1247 7 ай бұрын
Thank you Dr Jay 👏🏻👏🏻
@Birdylockso
@Birdylockso 5 ай бұрын
When I read up on these research papers, I always check the "Conflict of Interests" these days, to see who exactly is sponsoring the trials. I agree with Dr. Jay here that when money is involved, whether it's cholesterol or bp lowering drugs, one better double check.
@frankiefernandez5252
@frankiefernandez5252 6 ай бұрын
Honest analysis. New sub.
@dranthonyjay
@dranthonyjay 6 ай бұрын
honesty is the only way
@GHOSTDOG637
@GHOSTDOG637 6 ай бұрын
Top man. Thank you Dr Jay. Outstanding.
@dranthonyjay
@dranthonyjay 6 ай бұрын
My pleasure!
@adamgarthwaite5764
@adamgarthwaite5764 2 күн бұрын
Amazing content
@jeffs5519
@jeffs5519 6 ай бұрын
Glad I heard you, Im subscribed.
@hsvmed6026
@hsvmed6026 6 ай бұрын
Thanks!!!! I appreciate this sooooo much!!
@mikafoxx2717
@mikafoxx2717 7 ай бұрын
My great grandmother is 82 and has high LDL. She still drives, lives alone, and cooks all her own meals including meat and veg. My gramps is 75 and despite smoking, has always been active and cuts down trees and splits firewood, reroofed his house on his own the other year. Being active and eating real food, with adequate protien to retain muscle is essential. They probably also have decent genes, which I hope I inherited. Both have full heads of hair still. My other family members that haven't eaten so well and have much more processed food have beer bellies showing up in middle age
@jimfoulston8710
@jimfoulston8710 7 ай бұрын
Thanks, I really enjoyed this video. When you started and mentioned 5 years working on a phd, my initial thought was that you would be in the same camp as all the traditionally trained doctors, I was pleasantly surprised. When I first came across PA, I admit I was a fan, but have gotten to the point I don't listen to anything he has to say. He loves to say everything with such authority and if it is 100% proven fact. He was a big proponent of taking Metformin and would point out that it was not available to the average person, but since he is a doctor that he can take it. Turns out he was very wrong about that. When I hear any doctor spouting off about Apob, all I hear is, "we were right all along about cholesterol, but we were a little off about exactly what to measure, now we have it figured out and you still need to take a statin. I like that when you talk about certain lab levels you simply state the number. PA and others feel the need to always express the units of measurement, I suppose they think it makes them sound smarter.
@dwights1464
@dwights1464 Ай бұрын
PA is not the expert on cholesterol and lipids. Watch something with a real researcher like Ronald M. Krauss or William Cromwell. PA's ideas come from Dr Thomas Dayspring. Dr Dayspring is brilliant but I believe maybe resisting the intrusion of new research that conflicts with his own knowledge base
@askssk715
@askssk715 6 ай бұрын
Good timing. I just got my bloodwork back this morning. I'll be 58 in July and I'm menopausal. I've always eaten healthy, organic when possible. A few weeks ago I started low carb and no sugar and added more protein to my diet. I'm trying to only eat "healthy" fats. We only use EVOO and avocado oils in my house. Recently switched to grass fed butter in moderation. I'm still finding the best foods to eat, but all of my cholesterol numbers are showing in red. Total chol 233; LDL 152 and HDL 65; Trig 67. My fasting glucose was 95 and my A1c was 5.6. I had not had bloodwork in 2 years and my numbers are only a tick up. I'm also about 4 months now on an estradiol patch. I'm feeling pretty good. Never been on any medications and take vitamins sparingly. Since I changed my diet a few weeks ago, I've even felt my mood lift. I think I'm on the right track. :)
@jeffsilverberg5848
@jeffsilverberg5848 3 ай бұрын
I always thought that Metabolic syndrome was the key to everything, then I learned that insulin resistance is even more important, and then I learned that my glycemic index was the key to a long life. I guess I am going to have to go back to the drawing board. Just never enough blood work.
@unicornofthought
@unicornofthought 5 ай бұрын
time for your subs and likes to skyrocket. How are you not to a million subs yet?! :)
@CBass75
@CBass75 4 ай бұрын
Not sure why you came into my feed but I am grateful. I needed this video. Thank you 🙏🏼
@dranthonyjay
@dranthonyjay 4 ай бұрын
👊
@vicpdx
@vicpdx 27 күн бұрын
Could you create a content on glycocalyx lifecycle/health and how it relates to plaque.
@craftycalley
@craftycalley 6 ай бұрын
Excellent. Thank you.
@bobdec6665
@bobdec6665 7 ай бұрын
Grains turn to sugar immediately in the blood
@Cyberrjey001
@Cyberrjey001 6 ай бұрын
Exactly, there are no "complex" carbohydrates if your body has enzymes for them, and this chain of (amylose)-sugar-sugar-sugar-/-(amylopectin) just immediately converts to sugar, sugar, sugar...
@markwhatley9955
@markwhatley9955 7 ай бұрын
I’m 67, male, and went keto and IF, and stopped drinking in January 2023. Lost 60 pounds and 4 inches in my waist, (25% of my body weight); normalized BP; A1C in good range. Total cholesterol is 266 and my doctor stripped a gear and immediately prescribed Lipitor based solely on the cholesterol number. I had a stress echocardiogram yesterday and the cardiologist gave me a 100% clean bill….same as 7 years ago. But both he and my general practitioner INSIST that I am at a “very high risk for a heart attack.”
@dranthonyjay
@dranthonyjay 7 ай бұрын
😂
@genxer74
@genxer74 6 ай бұрын
Never heard of this channel before. Great video. Instant subscriber. Going to see what other videos he has.
@nickalicious44
@nickalicious44 7 ай бұрын
I'm currently on statin otherwise I've always been healthy but LDL won't come down even with healthy diet and regular exercise. My GP blamed my high LDL from genes from parents. Anyway, I've seen some biomarkers for CVE and I would like you to talk about these maybe on your next video. These are TG/HDL Ratio and TyG (Triglyceride Glucose) Index. I would greatly appreciate if you can speak to these biomarkers. Thanks!
@wocket42
@wocket42 6 ай бұрын
Why do you want to lower your LDL? That's the first question. There is no such thing as a stating deficiency.
@perijon00
@perijon00 6 ай бұрын
Why do you want your ldl down? It’s probably that high because your genes are making them that high because your body needs it in it’s current state.
@vin3421
@vin3421 5 ай бұрын
You’re awesome bro, spittin facts for the people. God I hate these corrupt industries.
@mariapapadopoulou7368
@mariapapadopoulou7368 22 күн бұрын
I like the way you think and that you re decent. Thank you. Humanity needs more like you. Greetings from Greece
@akumar7366
@akumar7366 5 ай бұрын
I've been on statin for 12 years, your Vlog has got me thinking, j have have never smoked or drink alcohol, I have mild clarification in one artery.
@brucemoose926
@brucemoose926 7 ай бұрын
Many doctors no longer believe saturated fat increases LDL. Like Dr Mason says, what's the biochemical pathway showing saturated fat to LDL?
@AKenton
@AKenton 7 ай бұрын
It clearly does. Mine went through the roof on carnivore
@jackoverton8343
@jackoverton8343 7 ай бұрын
There are multiple compounds in plants that lower LDL, paul mason in particular talks about plant sterols and has a few good videos on them. Not eating them then allows LDL to increase back to baseline. There is also the lean mass hyper responder cases where recently nick norwitz showed that you could then just nuke your LDL back down with few oreos per day(more effective than statins). So there are multiple reasons why your LDL went up irrelevant of sat fat increase. @@AKenton
@Miraak1868
@Miraak1868 7 ай бұрын
@@AKenton I am 80 on carnivore. I threw all my statins away when I saw studies that show seniors with high LDL have greater longevity !
@mikafoxx2717
@mikafoxx2717 7 ай бұрын
​@@AKentonNot the saturated fat, that's because of fat metabolism. Fat is transported in VLDL which turn into LDL once transfered. Your body recycles them quickly but overall level will look raised.
@rotabom
@rotabom 7 ай бұрын
​@@mikafoxx2717what??
@Wittbore
@Wittbore 7 ай бұрын
you can post it now? wasnt it only on rumble, anyway great that its on youtube because its easier to take notes.
@dranthonyjay
@dranthonyjay 7 ай бұрын
yes - it's demonetized but i won the appeal (different than Bill Gates' Apeel btw)
@HeatherDrew2550
@HeatherDrew2550 2 ай бұрын
Drs. Brown and Goldstein were 2 of my professors when they won the Nobel Prize for their work with cholesterol. I do believe they would not agree with much of the teaching that is out there about cholesterol and its (dubious) direct connection to heart disease. We've known for over 30 years that inflammation is a (or the) pivotal issue. Thank you for staying up to date with the literature and sharing it with all of us.
@323ddg
@323ddg 3 ай бұрын
Excellent!
@dranthonyjay
@dranthonyjay 3 ай бұрын
Thank you! Cheers!
@herbalannie7707
@herbalannie7707 7 ай бұрын
I have binged watched so many cholesterol videos. But I'm done for the nite with this one. You put my mind at ease by mentioning that that the acceptabe # of 300 for total use to be the standard. At 241 my doctor is hell bent on me starting a statin. I have told her NO 5 times. I'm about ready to find a new doc! Any way thanks for your research and the easy way you deliver it.
@TenTempeh
@TenTempeh 7 ай бұрын
Obviously you're eased by information that confirms your biases and doesn't make you change your lifestyle.
@brendaprice2951
@brendaprice2951 7 ай бұрын
I found a new doctor last week mainly for this reason and I think it's the best thing I ever done
@herbalannie7707
@herbalannie7707 7 ай бұрын
@@TenTempeh no it is not obvious, as you don't know me or what my lifestyle choices are.
@TenTempeh
@TenTempeh 7 ай бұрын
@@herbalannie7707 pretty predictable. Sad that you don't listen to your med, that is following the actual evidence, and instead let your health be the toy of these charlatans. Why would you have hypercholesterolemia? Either hereditary, either lifestyle, nutrition. Why would you say no to statins? Either conspiracy, or appeal to nature, or unability to acknowledge the severity of your condition. That last part would be the reason you'd appreciate this kind of content. But I'm here to make you reconsider seeing the uncomfortable truth instead of easing your mind into staying unhealthy
@keithcitizen4855
@keithcitizen4855 4 ай бұрын
I went back on statins temporarily while deciding it was punishment for eating wrong , lost weight etc now discovered the hype about saturated fat being OK doesn't suit my blood test results IE low triglycerides but raising LDL again , no one in the comments has answered why my blood tests come back with persistent mild thrombocytopenia diagnosis
@nancykennedy9397
@nancykennedy9397 3 ай бұрын
65 year old female here. Normal weight. Active, healthy and fit. Blood pressure normal. Blood glucose normal. Following a mostly low carb meat based diet. Triglyceride is low, hdl high ldl high. Last year after taking part in an alzheimers study the research fellow a young lady told me i needed to be on statins but my gp saw the same results and said they were fine. In april a nurse practioner ran my numbers for hrt counselling. Ive been on estrogen and progesterone for almost 2 months. I go for blood work again soon and she has asked for this apo b test. She was so concerned about my ldl. Hoping the estrogen helps somewhat. I really dont want to change my lifestyle. Ive been unhealthy when i was younger i dont want to go back to that
@monnoo8221
@monnoo8221 6 ай бұрын
yes. so true. People, including researchers and doctors do not understand that correlation is not causation, and that measurement does not imply making the root cause visible. Both can be made to look very scientifically, but in fact measurement and correlations are abused in 99.9% of all scientific work. There are structural and historical reasons for that, which we can not discuss here. Measuring something means to fish in the dark like a racoon, grabbing some changes in the system to make it visible. Most measurements are targeting proxies, not the root cause... because in a metabolic network, the root cause is not detectable at all. Yet, I think you are wrong on Lp(a). Lp(a) itself is caused to rise in a a regulated response to an injury that creates a small clot. Lp(a) tells the whole erst of the system NOT to break down a clot. This is very helpful in preventing the continuous bleeding from a wound. that is, first you have the injury, then the normal reaction of building a clot. this triggers LP(a). if there is enough healing capacity, the injury will heal and the micro clot will disappear. Yet any of those they can grow if there are lots of micro-injuries, now affecting themselves mutually and preventing their break down. So, the micro-mechanics of injuring the vessels are important to understand. those go from malfunctioning glycocalyx, largely due to inflammatory factors, external and internal (homocysteine), ox stress, low gutathione, high BP, and stiffness of RBC ...which by the way is related to too much saturated fat, relatively to the level of O3, and pufas in the cell membranes
@atransformedlife
@atransformedlife 6 ай бұрын
My only concern is that the study you were referring to was pertaining to lean mass hyper responders on a ketogenic diet… Correct? How does this apply to people with very high cholesterol on a Mediterranean or non-keto, genic diet?. I consume no processed food. No seed oils. No sugar. No gluten. Yet my cholesterol is 340. Still concerned this might just be a problem.
@MrLuba6a
@MrLuba6a 7 ай бұрын
immediately subscribed ❤ wonderful content! Thanks, Dr.Jay.Blessings 🙏
@dranthonyjay
@dranthonyjay 7 ай бұрын
Awesome, thank you!
@acjitsu
@acjitsu 7 ай бұрын
@@dranthonyjay Hi Doc, If inflammation is the main cause of damaged arteries(I agree completely), rather than taking a statin, why not just take aspirin?
@HopeOfJoe
@HopeOfJoe 23 күн бұрын
Thank you, Dr J. Gotta be the better 19 min on the subject. How do we contact you for would need to
@HopeOfJoe
@HopeOfJoe 23 күн бұрын
Figured it out ✌🏻
@StrongBDave1
@StrongBDave1 7 ай бұрын
Great information on inflammation and diet. l exercise and watch what l eat but after starting to put Nicotinic acid in the diet. Things just started feeling great everywhere in the body. What is your thoughts on Niacin it has been a good help with Recovery from exercise and well-being for me. 👍
@christinebowman90
@christinebowman90 5 ай бұрын
i think biochemists are the BOMB...keep it up,we can't afford for you to keep your knowledge to yourself.
@FutureLaugh
@FutureLaugh 6 ай бұрын
can plaques (hard or soft) in arteries go away with diet? exercise? medication? or is it here to stay and all you can do is mitigate more damage?
@dranthonyjay
@dranthonyjay 6 ай бұрын
they can be reversed, yes. ive seen it many times
@souvlakiG
@souvlakiG 4 ай бұрын
Research says it can be reversed with Cod liver oil, vit d3 with high dose Vit K2, Vit E ( not synthetic) Nattokinase and 2400 mg of Aged Garlic extract daily👍👍👍 Per Dr. sherry Rogers, Cod liver oil and Vit K 2 can MELT away plaque 👍🤗🙏
@jeffconwell4551
@jeffconwell4551 6 ай бұрын
Awesome video! Great info, greatly appreciated! I hit subscribed!
@computertooter
@computertooter 6 ай бұрын
I just found your channel and was pleasantly surprised. Thank you for quiting the Mayo Clinic. Their lose is definitely our gain! We need more people like you.
@hanko5750
@hanko5750 3 ай бұрын
I've been through three doctors as I changed my nutrition life style ... I don't like calling it a diet as in today's world a diet is a temporary thing people "try". I was brain washed over the years with the nutrition pyramid that is designed to make a person sick IMHO. I really appreciate the time you take to break things down so us who only speak "normal English" can grasp all of this. Thanks
@sotam1973
@sotam1973 4 ай бұрын
I feel overwhelmed by the conflicting information I read about cholesterol. There are good, bad, and new studies, making it difficult to understand. My total cholesterol is 390, triglycerides are 120, and HDL is 57. Although I eat a lot of saturated fat, I avoid junk food, exercise regularly, and manage my stress levels. However, my doctor told me that if I don't take statins, I will die soon. While I understand that most people take statins because their doctors prescribe them, I am still hesitant to take medication to lower my cholesterol. It's hard to identify whom to trust on this topic. Who is fighting for us? Who is fighting for pharma? Who fighting for LIKES and popularity? Our tools are very limited!
@carlsapartments8931
@carlsapartments8931 6 ай бұрын
so what is TRUE is that almost nothing is the truth... it's a version of or true with a large margin of error or just sloppy and useless or possibly even lies to support a bias!!!!! IT'S NO WONDER WE ARE HERE LOOKING FOR YOU AND OTHERS LIKE YOU!!!
@mannyradzky493
@mannyradzky493 7 ай бұрын
Thank you DR. You make the most sense of all the drs I have watched. 👍🏻
@christophermatarazzo4418
@christophermatarazzo4418 7 ай бұрын
Hello, To play devil’s advocate: The Tsimane tribe of Bolivia have some of the healthiest hearts in the world while they also have very high inflammation/CRP levels. Any theories as to why this is?
@dranthonyjay
@dranthonyjay 7 ай бұрын
send me the study title. i'll do a video on it
@lrn_news9171
@lrn_news9171 6 ай бұрын
Cigarette smokers tend to have worse diets combined with the smoking along with other factors. Which is often ignored when smoking is brought up and thus cigarettes are blamed for all their health deteriorations. Research also shows consistently that smokers have higher testosterone, but lower sperm count on average. Mixed bag in this regard. Overall smoking is bad but nicotine might have slight benefits.
@dranthonyjay
@dranthonyjay 6 ай бұрын
correct. i'm working on a video or two on this topic (just shorts) for later this week
@johnnyjohnjohn4216
@johnnyjohnjohn4216 4 ай бұрын
How do you stop LDL becoming oxidized? 🤔
@NateDohDoubleGee
@NateDohDoubleGee 4 ай бұрын
Don't eat garbage food (fried, fast food, sugar, HFCS, seed oils, etc.) and don't (or stop) smoking.
@dadesway
@dadesway 7 ай бұрын
Enjoyed the presentation so much. On the question of people with hypercholesterolemia dying earlier as a result of high LDL-C, there has been some questions concerning the cause. Briefly, it has been noted that *SOME* of the people with gene mutations that produce less effective LDL receptors (that hinder the removal of LDL particles from the blood stream and give them high cholesterol levels ). . . ALSO have genetic disorders of the blood coagulation system (which are likely to lead to atherosclerosis and early heart attacks). Those that suffer BOTH conditions typically die early because of the blood coagulation problems (usually < 30y of age) . Those that make it beyond 30, all things being equal, may expect to live a normal lifespan. In fact, a number of studies have shown that high cholesterol in the elderly is positively associated with longevity and slower cognitive decline. I must say that at the age of 73 I need all the cholesterol I can get. A paper "Importance of Coagulation Factors as Critical Components of Premature Cardiovascular Disease in Familial Hypercholesterolemia" Uffe Ravnskov, 2022 is worth a read.
@wocket42
@wocket42 6 ай бұрын
Yes. "The clot thickens"
@ajr3350
@ajr3350 6 ай бұрын
Excellent information. Thank you, Dr. Anthony.
@jmarriott5666
@jmarriott5666 4 ай бұрын
This has been known for a long time... the problem is McKinsey can't let this become accepted dogma. What would happen to carbohydrate crop farming, pharmaceuticals for your symptoms, and surgeries in hospital?
@MichaelDirk
@MichaelDirk 6 ай бұрын
Great Video. Thank you.
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