The Dark Side Of "Miracle" Fat Jabs Like Ozempic, Weygovi and Mounjaro

[@MarkLewisfitness]

Hopefully this answers some of the questions you had on my Mounjaro experience...

[@PBRF77]

Have you tried the moving house, and completely stressed out by solicitors diet?

[@MarkLewisfitness]

@ now THAT is high risk 😂

[@bobjames6622]

@@PBRF77 Ahh, I tried that one last year. The major side effect I found was hair loss....due to ripping it all out with sheer frustration! LOL!

[@mantelmann13]

There are some videos online even from bigger channels, reporting that Ozempic users are dying away.

[@PBRF77]

@@bobjames6622 LOL absolutely

[@daletocemd4781]

as a cardiologist, I commend you for your informative and inspirational videos--keep it up Mark...you are doing good in the world

[@robthewaywardwoodworker9956]

Honestly, you can't imagine how much I appreciate these videos. I enjoy all your content, but you talking about your relationship with food makes me feel like maybe I'm not crazy or alone. Thank you Mark!

[@freerunning]

Started last week my local takeaway made a welfare call.

[@MarkLewisfitness]

😂 then when bust

[@sorontar73]

This comment is golden 😂 bravo

[@andrewmcalister3462]

😂😂😂

[@pshoward]

It pays for itself.

[@chrisvanbuggenum871]

😅😅😅

[@Davey-tw2cr]

The humor is why we click. The desert skit had me crying.

[@tubesomething]

I also leaked fluid.

[@rebeccaroberts7114]

Just LOVE these Mounjaro videos!!! Why ? Well because they are plain old COMMON SENSE! I suspect, but don’t know, that any negative comments are mostly from condescending slim people? So please keep us all updated on your journey, and huge thanks from an old lady who enjoys a giggle 😊

[@lucypeace6132]

I paused to come find this video! 🤣

[@robertellis1390]

I just found your videos and the Mounjara content grabbed my attention. I started taking the drug in April this year and have lost 70lbs upto date. As well as taking the medication I also joined the gym and go almost every day, I changed my diet to a low calorie high protein and non processed food diet, I also quit drinking alcohol. I had a very unhealthy relationship with food and I totally resonate with everything you have spoken about your relationship with food. I have gone from being, Obese, borderline diabetic, high cholesterol, unfit, to being perfectly normal. My GP is stunned with how I’ve turned it around. I am currently weaning of the drug and will be free from using it by the end of the year. Total game changer for me after struggling walking past the cookie jar for years. And I drive a truck for my living. Worst job ever for over weight people?

[@robinupham1975]

That's amazing!

[@oceancat0450]

What kind of doctor do you go to to get these injections? Youre story is wonderful.

[@oceancat0450]

What kind of doctor do you go to to get these injections? Youre story is wonderful.

[@endlrls]

Mate, I drive Semi for a living and literally I'm one of the few healthy drivers at my company with a 2 year medical card. It's actually impressive how many of my co-workers just don't seem to be bothered by a 1 year card not to mention to myriad of drugs they take to be "DOT legal". Thanks for the comment! :D

[@randyduane5370]

I've been using Tirzepatide (Mounjaro) for 13 months and to date, I see no downside other than mild nausea for 2-3 days following my injections which are now every 10 days to 2 weeks. Costs me roughly $200 per month is a downside. Lost 50 lbs. while lifting and doing cardio for a year now and in terrific shape at my ideal weight for 61 yr. Clear check ups at Dr. Weight: 200 Blood Pressure: 123/75 no meds. Resting Heart rate: 57 I feel great! Couldn't be happier.

[@MmeDesgranges]

Sweet

[@him050]

“Public opinion” “Couldn’t give a fu-“ Never change, Mark. Never change 😂😂😂

[@alicejwho]

But, he could give an f. Because if enough people leave here, his lifestyle would be compromised.

[@patty109109]

@@alicejwhoI wouldn’t overthink it 😊

[@alicejwho]

@@patty109109 oops, you're right! 👀☺️

[@aprillynnhawaii]

Love your sense of humor. Talk louder for the people in the back! I’m on Mounjaro and have lost 30lbs in 12 weeks. Amazing. Life changing! Could care less what others think. I feel good! Keep going guys!

[@toniwright9163]

I don't normally comment on these things. I just wanted to say thank you. Your last video was the decider for me to try Mounjaro. For the first time in what I can remember in 50 year, I am not hung up on food. The food devil on my shoulder has been flushed down the loo. I am no longer getting stressed and hangry. I haven't been out and bought ice cream, cookies, cake to then vomit it all back up. I actually feel normal!!! As far as what I assume normal is. I had a Dr Appt. Monday over HRT. I told her that I had taken it and how it was amazing to finally feel like a normal person. She is now wanting to research this, hopefully to help others. She was absolutely made up for me. So as you say, I don't care either about the future. It is helping me be a normal eating human. THANK YOU

[@l.c838]

I think keeping it at a low dosage is key to not having the side effects. I’m so pleased that it is working so well for you. 🙏

[@DollarDude]

2:03 "Desserts" 😅

[@shaunedwards4362]

Yesss was gonna say the same😂😂😂😂

[@aeit999]

Based

[@RossTheNinja]

Best dessert. It burns calories too.

[@shaunedwards4362]

Sure does​@@RossTheNinja

[@johnshelton1234]

I'm just into my third week on Mounjaro and it certainly does what it say on the tin. I'm keeping a detailed food diary, getting my 10,000 steps in every day and now back at the gym doing weights three times a week. Because I'm 72 years old, my biggest concern is loss of muscle mass, and because of the suppressed appetite, I'm finding difficult to get enough protein into my diet, but my constant low level depression and fatigue seem to be waning, which is a big bonus. My game plan is similar to Mark's; keep on in for 3 or 4 months and then have a Dexa scan to see where I'm at. Did the Hyrox team event in London last November and now looking to do a doubles next year and a solo before my 75th birthday. Thanks, Mark. Your videos are really inspirational. One last thing. If anyone is considered Mounjaro, IMHO, Johaan Hari's book 'Magic Pill' is definitely worth a read for balanced and nuanced view on all the issues involved.

[@tobyedmonds72]

"Greedy motherfu" is by far the best Jenna cameo yet 🤣🤣🤣

[@MmeDesgranges]

I guess we need to meet ML's Mum now then

[@bigb7422]

I totally agree! I laughed out loud!

[@marinabanovic3168]

😂😂😂😂

[@robertoneal7508]

Earned my sub!

[@carlwhitley9591]

Great video. I've been using this for just over 3 months and I'm almost 4.5st down. Some of your comments just ring true. I may have lost muscle mass, but that's because I don't need it to carry around almost 30kg extra, all day, every day. Eating is more controlled - haven't touched a McBreakfast since starting, haven't had pie lunch at work since starting. Have decided to just go for a run and extended it because I was feeling good. Have been able to exercise with more intensity/for longer/more regularly because I'm not fighting a recovery battle. Absolutely life-changing for me.

[@ChaseTheMoments]

I have been on this for 6 months and can tell you that it has been very positive for me. 51 pounds down and feel great. Food noise has gone and now making natural healthy choices. Nothing is off limits. Yes, I have lost leg muscle but I expect thats because I am not carrying 20KG everywhere I walk.

[@Finely_shredded]

As always love the humor. Jokes were on point and the “supporting wife, you greedy f…” had me rolling. Also love that you always weave a positive message into these. Really great work. Especially knowing that you’re doing it while moving on a couch in a room full of boxes. That’s dedication to your craft.

[@grantthepilgrim]

Hi Mark, I hope you sort your housing out soon. I was contemplating this for some time. When I watched your last video, I went online & made an appointment with my Doctor immediately. You may think I was impressed with the weight loss, and don’t get me wrong, I am, but it was what you said about turning off the voice in your head that almost constantly prattles on about food that got me. I’m 53, BMI says I’m obese by 20+kg, but I’m active and I’d say, fit. I did a 50km trail race a few months back & have another one in a few weeks. The near constant thinking about food was driving me mad. I started mounjaro a few weeks back & the effect was not immediate, but within 24-48 hours the voice was largely gone. I haven’t weighed myself but I feel great, physically but more importantly mentally. So thanks mate, I really appreciated hearing your honest thoughts on this medication. Ps. I’m a Solicitor & offer my humble apologies on behalf of my profession, some Of whom are wonderful people & some a bunch of dopes. Take care

[@marcschulwitz4078]

Sprinkeling Chocalte Chips on Jenna's belly just had me rolling on the floor :D You are the king of funny and informative videos, please keep them coming!

[@MmeDesgranges]

Who says it was J?

[@brigitteboulais5474]

I know ... 🤣🤣🤣

[@brigitteboulais5474]

@@MmeDesgranges😂

[@kbr2121]

I laughed out loud😂

[@hilarygibson3150]

I started Mounjaro last week. I'm 60, gor the first time in my adult life I don't have a war going on in my head. It is beyond amazing. I eat food because I need it, not because I feel - well know! - I can't stop myself. Yes, I worry about finishing it, but I can only cross that bridge when I come to it. But with my parents dying in their 60s from circulatory issues, I'm hopefully dodging that bullet or at least deferring it.

[@Stuey001]

100% - I’m just over a week in. In part thanks to Mark’s original video on this I decided to give it a go. The reduction in “food noise” in my head is remarkable, and that’s on the lowest dose. Genuine game changer.

[@talonlan]

awesome well done

[@hilarygibson3150]

​@@talonlanthank you

[@colinb8327]

Mark, thank you! I had shied away from using the jab, but your previous video helped me gain some clarity and realise I wasn’t alone in my thinking. As someone who used to be very fit, it came as a real blow when in 2020, I was diagnosed with 6 growths on my lungs. The combination of inactivity through not being able to train, medicines, medicational steroids, stress and the normal low feelings/depression, led to the comfort eating spirals you mentioned. Then when I finally got the all clear much fatter and unfitter, it ended up as train, don’t lose enough weight in the time I expected, eat to comfort, eat because eating to comfort made me feel worse……. So thank you, your video gave me the slap I needed to realise that it’s my life, screw everyone else’s opinion, and if medication put me like this in the first place it can bloody well sort it out! I had my first jab Monday, let’s see what happens….

[@peterholdsworth]

Another great vid!!! I'm now down 117lb on Mounjaro since Feb - without side effects! People expect this to be a magic injection which melts fat while they eat and drink crap. Slow digestive system helps you recognise what food don't agree with you. You MUST alter your diet on GLP-1 medications for the long term success after finishing the meds.

[@MmeDesgranges]

100% you have to alter your eating decisions to suit incretins. But once you dial that in ...

[@Musicjunkie557]

Totally agree.

[@me-lg1yw]

I first started watching your videos when I was in the market to buy a Garmin watch. Now, I watch for your dry humor no matter what the topic.

[@mypojam]

same journey. I think he did a video on Garmin Epix or something and dude cracked me up, I actually LOL-ed! Subscribed ever since

[@Emmaly104]

Same...came for the Garmin... stayed for the humour 😊

[@1588chrissy]

I’m with you, I don’t care about public opinion. I have mental peace for the first time in my life - I am not thinking about food, tormenting myself about what I ate, waking first thing and immediately thinking about what’s in the kitchen. I can walk away, I can leave things. I haven’t binged in months. I would like to lose another 2st (have lost 2st) to reach a vanity weight. My disordered eating has cost me alot over the last 30yrs - frankly I don’t care if I use this for life. Yes, I would love to titrate down (am currently on 12.5mg MJ) and maybe get off it eventually, but equally, if that doesn’t work and the binge returns, I have no qualms about remaining on it. It didn’t melt away fat in my experience but it gave me the mental clarity to deal with food differently.

[@MissUlfang]

I've watched your videos quite a few times and this was the one that convinced me to subscribe. I hope your issues with food get easier for you to live with. My mother has struggled with her weight since childhood and did actually receive bariatric surgery only for her gastric band to fail. Her quality of life was really rubbish, she couldn't enjoy a normal meal with the family and it really impacted her social wellbeing. Now she's taking weight management medication, under the supervision of her doctors, and is getting closing to a normal weight for the first time in her life at 55 years old. For the first time ever, she actually seems happy in her own skin. Like you, she struggled with emotion driven eating patterns and has only now had the mental breathing space to adress her issues. All of this to say: thank you. I think I understand her struggles much better now.

[@ConorOD451]

I started watching your videos because of the interesting, varied fitness content, but I stuck around because I seriously resonate with your experiences with disordered eating. I'm a fairly active 36 year old man that hovers between "in decent shape" and "slightly overweight". If I wasn't so active, I'd likely be in the "very overweight" category by now. My binge eating is triggered by stress. And also boredom. And just generally being awake. I'm not planning on hopping on Mounjaro yet, but I'm very interested to follow your journey with it.

[@skip3619]

I’m a very active and generally fit 36 year old, used to be morbidly obese at 18/19 but have continued to struggle with binge eating disorders and poor discipline on weekends. I’ve been on Wegovy for a week and a half and… I’ve never, not even when I had mono or the flu, thought about food less in my life. Still counting macros and eating only short of maintenance cals (low and slow to avoid muscle/bone density loss) and it’s going wonderfully. Do some research, have a chat with your doc. Pretty promising so far.

[@wesyoung91]

Mark, I've gotten a similar effect from starting adderall this year after an ADHD diagnosis. Like you, the desire to eat has always been so strong and so loud. Starting treatment for the ADHD really turned the volume down on my appetite a ton. I'm in a pretty good place right now where I don't really pay all that much attention to what I'm eating. I have just naturally started eating so much less and the weight has just been falling off. Not being driven by my appetite has been such a life changer for me. I was a nightly binge eater before and now I eat two very reasonable meals per day without the urge to snack.

[@andreacook2416]

There’s a big overlap between adhd and binge eating.

[@Alyssasrosegarden]

People who call out obese people for taking medication like this prove that it was never really about "being worried for their health" it was always about wanting to feel superior over people who struggle to lose weight.

[@buddhamack1491]

Great saying I was told at a young age. Never accept criticism from someone you wouldn't seek advice from

[@ArtFlowersBeeze8815]

I'm a fat girl who has felt superior to others who are fatter. Sigh. It was such a terrible way to exist. Now I hope my friends are happy and healthy. Its not their struggle to be better, but mine.

[@lynnezabek]

Yes ! Exactly this.

[@konraddapper7764]

So poeple that worried about obese peoples health cannot worry about largly unknown health complication from a hardly studied medication? That is 100% consistend.

[@cloakster]

@Alyssa Definitely some truth to this. Have never understood why some ppl are so obsessed with how OTHER ppl lose weight. 😒

[@bradporter9922]

I've been watching your content for a few years now Mark, I have found myself in a very similar situation to yourself when it comes to eating in a very disordered fashion. I have always been an advocate for doing things the hard way i.e no use of medical interventions to assist with weight loss/maintenance, but after a few tumultuous years of yo-yoing weight, some medical issues, including a bout of Atrial Flutter and a diagnosis of Sleep Apnea I have found myself in a fairly deep rut where I have struggled to get myself back into the shape I was 1.5 years ago where I ran a 1:37 Half Marathon, and it has been quite depressing to say the least. When I saw your video a few weeks ago about going on Mounjaro, and how relatable your fitness journey is to mine, I have decided to give it a try. I hope you continue to keep us all up to date with how you go with it, but so far it looks like it's doing you well, all the best from here in Australia, look forward to watching your progress.

[@christophersreef7644]

I watched your first video and decided I needed to take the risk. I was 207kg or 32stone… after a week and a half I’m 198kg or 31stone and my god that isn’t the best bit. The best bit is the mental clarity! It’s changed my life so far!

[@antj29]

Great isn’t it, only those who were addicted to food will understand that. When you’ve sat there and eaten two large dominoes pizzas, sides and a desert to the point where you feel ill, then on the drug you feel full after just a small microwave meal,,,,, and you don’t go out picking, then you suddenly realise what it’s doing…… I’m 36kg down in just over 3 months

[@christophersreef7644]

@ great stuff, good for you! I’m nearly two weeks in and I’m down 6kg. Sure it’s early days but damn! Being addicted to something is hard enough, but being addicted to something you can’t stop is just cruel. Smokers, drug addicts and alcoholics can all work to being sober. But I can’t, if I stop eating I’ll die. But with this I have such mental clarity, I’ve also noticed I’m way more willing to cook and make a meal vs a takeaway. Not sure how or why… and to be honest I don’t care. This has changed my life.

[@Musicjunkie557]

Superb video. I am 7 months in and lost nearly 3 stone. GP is amazed how I have reduced cholesterol from 8.6 to 5.9. Only downside is the cost. This is a game changer for so many reasons 🎉

[@flynnnrg]

I really appreciate how honest and informational this video came out to be and am really happy that you found something that helps you mentally and physically.

[@Auntiegm7268]

Thank you so much (from Canada). I tried Mounjaro this week and for the first time in 56 years NO FOOD Noise

[@brightknight1965]

Love how candid you are with this stuff and with trt as well. Hope the move improves and that we get goat videos soon!

[@HealthAtAnyCost]

In your last video's comments, I outlined my 260 lb. weight loss on Mounjaro (also NOT sponsored... they don't know I am alive, though they should!). I have been on GLP-1s for almost 2.5 years now and have been on 15mg. of Mounjaro for 10 months and there has been not one tiny bit of a difference in appetite supression or satiation. 15mg still works great for me. I also will be on Mounjaro (or one of its children or grandchildren) for life. Before Mounjaro, I would have been on insulin for life or, more likely, dead from being so enormously sick with fatness, so being on a GLP-1 for the rest of my life doesn't remotely concern me. Mark, I have never watched you before, but I love you. Thank you for your real-talk and understanding people like me who have rarely been understood before.

[@daramaccarthy]

Love the solicitor rant - correct 🤣🤣🤣

[@debbieleno3774]

I've been on mounjaro 2.5mg for 7 weeks, I didn't feel the need to increase my dose as I didn't want to always have the strong suppression that I felt in the first week. I've lost 21 lbs in this time, I'm now more active and feel it has given me time to learn some new eating habits. I'm coming off it next week so will see how it goes but I'm feeling positive 👍

[@owen-trombone]

Congrats! I hope the transition goes well for you.

[@talonlan]

awesome well done

[@MmeDesgranges]

The smaller the dose the less chance of side efects

[@samswift4841]

15 seconds in and already the production value on this new era of videos is unparalleled!

[@FlatToRentUK]

As a good friend once told me about solicitors - if they were any good they wouldn't be conveyancing. Absolute truth.

[@jamiepike6909]

As an adult I’m going to give this a go, which is 100% my choice. I’m nearly 50 and my diet is terrible, I run a lot etc. and people say I don’t look overweight (just under 14 stone), but I am and if not for my running I’d probably weigh 18+ stone. This sounds a lot like you🤣 If this can stop the binge eating I’ll be happy. Thank you so much for your videos on this❤

[@MmeDesgranges]

I hear ya!

[@firbolg]

During my entire adult life, I've been overweight (between 75 and 105kg at 1.65m). Next month, I'm starting a new treatment that finally addresses my condition. When I was 15, I had a severe bicycle accident that led to several hormonal deficiencies, which remained undiagnosed until now at age 45. I'm hopeful that taking growth hormone (alongside hydrocortisone and thyroid hormones) will help me feel more energized, lose weight and, most importantly, reduce my visceral fat. This, combined with exercise and working with my dietitian to address my eating disorders, should help improve my health.

[@talonlan]

Awesome hope all goes well and thanks for sharing

[@owen-trombone]

You can do it. You are on the right path and that’s the most important thing.

[@MarcKent]

“Deserts” followed by sprinkling chocolate chips on Jen had me laughing out loud 😂

[@petevito]

Mark your last couple of video on this have hit a spot with me and a few other guys on here... Struggled with my relationship with food all my life... Some may say just eat less, but thats the same as me saying dont gamble or drink.... Great couple of videos and hope the move goes well...

[@ngogol1748]

I think the last video got more criticism for its editing then for the actual content. ;) I am happy you fixed the editing. And thank you for your thought provoking arguments. I stay very skeptical with these medicaments, but the way you put it, it is much easier to talk reasonably about disagreements. This is such a rare attitude nowadays!

[@DigitalDirtFarmer]

Mark just found your channel thanks for the joys of KZbin algorithms. Great watch and can relate to so so much. Struggled with my weight since I was 19 years old. After I tore acl playing cricket I went from playing sports 7 days a week to nothing for two years. I was majorly overweight but have two sons aged 13 and 12. I want to be around to see them getting old! As a single dad I find it hard to cope but I have turned it around this year. I’m down to 18 stone and going to the gym on the nights I don’t have my sons. Going to be going through your videos tonight for more inspiration. Thank you

[@jamesgs27]

buddy, I love you, I love your sense of humour!!!! You are so brilliant at this job!! Keep um coming!!

[@DarylBatCarer-ms7od]

Love your honesty and content Mr Lewis. No matter what you talk about I always find your depth of research and self awareness inspirational. Good luck with the legalities of moving and I know we're all looking forward to Farmer Mark. 🤠

[@HamishBrinkman]

Mark, loving your videos and your sense of humour, keep going, very informative and honest.

[@Grunfeld]

Great reflections. Appreciate your perspectives Mark, I find them helpful. (And may the move go well!)

[@andrewthomas9305]

One of the most useful and real video I have watched in a long time! I’m about to start my Mounjaro journey and your videos have been so helpful. Thank you 🙏

[@sarahwatts9555]

Loving the fact the Tube showed me your videos! Need to make a point though, just in case anyone in my phone is interested. It ISN'T a super speedy, miracle weight loss drug for everyone. I am currently on my second week at 5mg dose of MJ. I have Type 2 diabetes, diagnosed Feb 2024, caused because I am a fat blimp. Even on this medication, which i AM paying for before anyone comes at me because it's available for T2 (it is? Tell my GP please) , I am not losing weight fast. In fact no faster than without. Yes, I'm in a calorie deficit, no... I'm not very active(see above- fat blimp comment). I'm working on it. But for some reason my body does not want to let go of the blubber, even though the food noise is so quiet, I forgot what chocolate, cake and biscuits are for, and the only bread that passes my lips is my own home made wholewheat sourdough (once a day for breakfast). Also, no major side effects to speak of. I'm sad when I read all these amazing weight loss stories and I'm here, plodding on. Just want your people to know it doesn't make the lbs fall off for everyone. Wish I knew why....

[@crosshaircycling7156]

Don’t get disheartened. It’s because your metabolism is broken. That’s what T2d does. Your cells are burning sugar not fat. Give it time to get the T2d get fixed and then your body will learn how to burn fat and the weight loss should begin. Despite his food relationship problems- mark has healthy and high-functioning mitochondria. The appetite suppressant was all it took to let his body do what he had trained it to do. He only had to fix the calories in side of the equation whereas you have to fix both.

[@yottao2]

Brilliant answers in both of Mark's videos. I think for most folks the disappointment is that these aren't "have your cake and eat it too" jabs. Now that would be the miracle

[@paruvo9968]

So Mark, I was watching "Sprint" on Netflix US and saw footage of Usain Bolt and I saw YOU. I looked up his height 6'5". Sometimes you downplay your accomplishments but I, a 73 yo female stranger can see "it" in you. Keep on bringin it!

[@A7ftt]

Wishing you all the best. Your videos are excellent, balanced and extremely well delivered.

[@Stealthoneill]

I'm just finishing my first week. The complete lack of food noise is staggering. I've had zero side effects so far. At a BMI of 40 and trying my hardest over the years to lose weight but now I'm working on eating the right food, hitting protein goals and the medication is a tool to enable me to find my right level without the constant craving. I figure at 6'8, 360lb and closing in on 40, the risk of obesity far outweigh the risks of Mounjaro right now.

[@BSelf2105]

As always, great content. I signed up to it after your last video and feeling the benefits. The way I would describe it is I don't feel sorry for myself if I don't eat and don't feel the need "treat" myself. No side affects either. So far, so good..

[@gavinstrawn6833]

At first so was wondering why you posted at 5am. I immediately remembered I am in the central US, well across any pond from you.

[@MmeDesgranges]

That's why we love Murica

[@DaveyFamily]

Love your videos mate, always honest and straight to the point with great humour 👍🏼 I’ve struggled for years with eating and have looked into this myself a lot over the last few months and really enjoyed these 2 videos,

[@techidna-h9t]

I appreciate your clarity of purpose and rational approach to the "chemical diet".

[@nimblybimbly4002]

0:28 It's jarring every time the "before" is on the right.

[@Islandlea333]

I started today . Ive always been a fitness freak till i hit 40 and ended up with spinal stenosis. And got really unmoved due to pain and pain killers. So now ive quit the painkillers and hoping to get back mountin biking. My absolute joy and dance.

[@bryanwalsh1107]

The John Hurt cameo made me lol - well done.

[@jamesgalbraith5011]

Great video Mark. I love your sense of humour, keep up the good work. Good luck with the move 👍🏻

[@Spendarellaa]

Hi Mark I’ve been enjoying your content for a few years now. I have a medical background and special interest in diabetes. Recently attended a Diabetes study event at Olympia. One of the key topics was the side effects of GLP-1 agonists, particularly the high levels of muscle mass loss. I mention it here because I notice that you didn’t and it’s not commonly known. There is heterogeneity in the reported effects of GLP-1-based therapies on lean mass changes in clinical trials: in some studies, reductions in lean mass range between 40% and 60% as a proportion of total weight lost, while other studies show lean mass reductions of approximately 15% or less of total weight lost. Citation- Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies Ian J. Neeland MD, Jennifer Linge PhD, Andreas L. Birkenfeld MD First published: 27 June 2024.

[@jaydeeao]

Here you are providing a very good and educational (based on personal experience) video, and I'm over here checking out your motorcycle. Good stuff man!!!!!!

[@1519Spring]

He's done a video on that (both what and why).

[@jaydeeao]

@1519Spring Thanks, I'm going to have to go through his other videos and check it out.

[@helenhascatallergy413]

I love your dry comedy and the way this is cut... wife holding the chocolate chip jar - made me snigger, seatbelt extenders - I laughed out loud. Good luck with your solicitors and the move.

[@danforber9181]

I’ve just taken my 1st dose thanks to your 1st video, I’ve always struggled with over eating, it’s always been a worry when getting lunch or making tea that i won’t be full so I make too much and scoff it even if I feel full. I’m hoping that a few months Mounjaro will help in the short and long term to stop eating with my eyes and let my body tell me when it’s had enough

[@seanprendergast961]

I started on Mounjaro this week to help control my blood sugar levels. I am taking insulin already for type 2 diabetes. I did an awful lot of reading too before agreeing to use Mounjaro. Week 1. Felt quite ill on the 2nd day. But nothing too much to worry me. I hope this helps me. Thanks for the informative video Mark

[@michaelbruno5075]

Mark, way to keep it real brother. Keep it up!

[@Once-a-fatman-nownormal]

Your 100% correct well as far as I’m concerned I had virtually the same experience as yourself, no side affects and only a positive experience

[@samuelbino7915]

I will always watch your videos mark 'probably' as whatever subject you cover always has a take away from it but I do miss the earlier content that had you taking on challenges and sharing your prep and training etc...i dont think you exhausted that content at all, as a 47 year old, I found that above average concept really motivating and seeing someone doing it across a wide spectrum of disciplines was great 👍. I guess everything has to evolve, no doubt I will still be watching when you are doing vids about farming and the techniques on sheep shearing in a few years time.

[@waynemoore743]

Thanks Mark, I’m doing the same as you by my own choice and logic before I ever saw your vids. Brilliant stuff and thanks for sharing. Good luck on your journey man.

[@toddie3910]

I started on Mounjaro last week - woman, late forties, 99kg (so yes, obese). And I've actually been turning away food!!!! What madness is this?!? The reality with all this is, it's no magic jab. We still need to think about fueling our bodies with the right nutrients and working out for the sake of our heart, muscles etc All of that doesn't magically cease to be necessary. What the jab does (for me) is help me to look at food through more sensible lenses. Oh and no nasty side effects. Yay! Looking forward to what the next few weeks and months bring 😊

[@talonlan]

Awesome well done.

[@SBNewMe]

Good luck - I just started carnivore(ish) and cravings have stopped in a similar way - I need to find out why the effects are similar!

[@MmeDesgranges]

Keep the faith!

[@sxhrgvs]

Interesting and useful. Looking forward to seeing how you progress. Thanks mark.

[@alexherts7953]

PCOS and the metabolic syndrome/ insulin resistance has made loosing weight and staying in calories deficit incredibly hard. I’m active (weightlifting, running on top of bouldering and overall active lifestyle). Following a chat with my GP, (BMI of 29), I started Mounjaro 2 weeks ago. So far down 3kg. No side effects (maybe twice I was a bit nauseous for 30min). I feel like the constant noise in my head wanting me to keep eating despite being full has reduced and I don’t get as big glucose spikes. This is a game changer and such a relief.

[@MmeDesgranges]

Sweet

[@OwenB98]

Im not a people person but i could talk to someone with your outlook for hours on end. A true gentleman trying to improve his life and help others at the same time.

[@josedelatorre7560]

Great content as always, was just finishing a question for you asking about if you were going to Dexa scan and report back about the muscle loss claims by Peter Attia (among others) and then 8:39 came. Thanks for the insight and GL with the move!

[@Journeyoflee]

Only eat Labrador’s on a Friday diet absolutely got me 😂😂😂😂😂😂😂I’m straight up stealing that - hope your well Mark👊

[@sigfreed11]

Looking forward to hearing your thoughts on pulling off it - thanks for the great content

[@arthogof]

Thanks Mark, love the no bullshit stance! Good luck with the move!

[@fatblades]

Superb video! Can I just ask what dose you’re on? Did you maintain 2.5 or increase? Thanks

[@Kieran-ky9dp]

Excellent video again Mark.

[@BoiledOctopus]

Hugely entertaining and interesting to watch. Subscribed!!

[@michaelbyrne6180]

Great stuff Mark. Really enjoying the videos 👋

[@SamHarrison2099]

Your discussion of disordered eating has always sounded very familiar to me, and you talking about the lack of food noise on the jab sounded revolutionary. I wish I could get it prescribed or something though, it’s quite expensive!

[@nadinecarr6530]

I used a drug called Champix to stop smoking and I haven’t had a cigarette since (20 years ago). I often suggest it to people but am met with ‘oh what about the side effects?’. People often are in denial about their health unfortunately. Good luck! I hope it works for you.

[@gouldj4029]

I used champix as well and haven't smoked in 10years. It was a magic pill to me. I remember wishing they could have something similar for junk food and chocolate. Finally they have, mounjaro is that magic drug for bad eating.

[@paulinehilling3830]

I’m vegan female on HRT & testosterone I’ve started on mounjaro week three I was 21stbmi 50 in 3 weeks I’m now 19sr 9 bmi 47. Two bouts of sickness both my fault. 1st week due to very fatty food I over ate. Yesterday it had gotten to 2pm I naughtily wanted to eat & drink water but had only sipped water that made me feel sick. I would say that’s a good thing. I’ve come of my 2ltrs a day Pepsi habit that’s take a while to not feel headaches. I can now walk better & im not mouth breathing as much. I took a nasty fall the week before starting this where I face planted the floor. I need my mobility. I agree with both his videos it’s silenced the chatter about food. I am sleeping so much deeper. Given I’m perimenopausal that’s been such a blessing. I’ve actually started to dream again because I’m asleep for long & deep enough. We need fitter people but especially males to test this too it’s how female over weight voices are validated. I for one Thank you xx

[@hulkthedane7542]

Muhahahahaaaa, you got the diet wrong. Labradors are for Sundays, German Shepherds for Fridays...... 🤣 I LOVE the images you put out verbally 👍👍👍👍👍

[@Stu_2112]

You really are a breath of fresh air. Thanks for what you do.

[@greggster100]

Brilliant and funny as always 😂 Most of us wholeheartedly agree regarding your solicitor comment

[@jonsaxby7683]

Very sensible video mark, I've been on the other end of the disordered eating scale having spent alot of time in my life underweight so i know what its like to not have a "normal" relationship with food and how hard it is to deal with the overwhelming urge to do something you absolutely know isnt going to do you any good but you do it anyway, imo the jab should be seen as one of many tools available for people to use to help them address health issues caused by disorderd eating and the associated health conditions, clearly it won't be suitable for everyone and some of those people its not suitable for shouldn't be allowed anywhere near it (me being one of them, thankfully i found therapy which i found works for me) and those that do use it should do so via a medical professional and not someone with a Facebook degree who says "trust me bro I've done my research"

[@stevepowell8395]

As always, a very straight talking, factual video that should be very helpful for so many people. Love that fact you don’t give a s%!t what others think.😄

[@FGsquared]

I feel you so hard on the food noise. I've never not had a single day in which I don't think about food or eating. 2 years ago, at 38, I was finally diagnosed with ADHD and it all makes SO MUCH SENSE. Food is my dopamine source of choice and ADHD makes it all so much harder because it lowers impulse control and hinders executive function. But knowing is half the battle so I managed to loose 78kg just after getting the diagnosis. I'm still struggling with the food noise so much which is why I'm pursuing ADHD meds now which are also known to lower food noise significantly!

[@lutfizakhour]

Another great, honest, open and funny video! Thank you! Question for you: has your resting heart rate gone up, and is this affecting your exercise, running in particular? I’ve noted that my RHR has gone up 10 bpm from low 50s to high 50s and it is making my running less enjoyable. Does this drop with time? I’ve been on Mounjaro 2.5mg for about a month now. If anyone can comment on that I would be eternally grateful! Thank you!!

[@antiperspirant]

I have a BMI of 32... I'm 5ft8 so I'm not "too tall or muscly" changing the scale, I actually tried this last week because of your video, and down 6lb... I've had no side effects and it's honestly changed my diet so much, because I'm feeling good about losing weight and diet I've started walking and lifting some dumbbells and as of today just signed up for a gym. Thanks for making these videos.

[@zigziar]

Just a word of caution, while you are not aware of any side effects studies have shown that for every 10-lbs of weight loss, upto 4lbs of that is lean weight, e.g. muscle and bones, which can take a long time to get back, if ever, especially the more you advance in years.

[@talonlan]

Awesome news great work

[@andrewbonhomme8069]

I see many similarities to you and I and I seem to see it all in a very similar way so I’m enjoying the content to confirm my ideas. Keep it up it’s an angle on a product not many have thought of

[@rohobok2890]

Hahah that sprinkling of choc chips on Jen's stomach made me laugh.

[@briantimson1397]

Very informative content delivered in the best possible way 😂

[@gmonkmoby]

Great video. I'm on week 3 and so far it's going great. The only side effect I've had is when I've drank about 3 pints of beer, afterwhich I didn't want any more and felt nauseous most of the following day. Other than that, food noise gone, eating right sized portions of healthy food and feeling full all day, no more snacking! Weight has gone down and energy levels are steady throughout the day.

[@vg3222]

Really advise against you drinking any amount of alcohol when on Mounjaro…

[@juliearmstrong9648]

Ha ha love your wife's comment ! This video is so relatable and informative x