The Ultimate Crash Couse on Folate - Signs & Symptoms of Deficiency, Function, Detox, & More

Supplements discussed in this video:
5-MTHF (Methyl Folate) - bit.ly/3mPiBxe
Vitamin B12 (Methylcobalamin) - bit.ly/2MPaN14
Magnesium (Aids methylation) - bit.ly/2LjE14J
B Complex (Methylated) - bit.ly/38wEcnW
Multi Vitamin with B Complex (Methylated) - bit.ly/2jWTVbD
The Ultimate Nutritional Crash Course on Folate
00:00 - intro and overview
01:39 - functions of folate
02:15 - symptoms of folate deficiency
07:48 - methylation cycle
14:00 - macrocytic anemia
16:50 - conditions caused by folate deficiency
21:54 - gluten sensitivity and folate
24:00 - folate vs folic acid
29:20 - drugs that reduce folate
32:00 - folate rich foods
33:15 - folate supplementation
38:47 - Q&A
To connect with Dr. Osborne visit:
On the web: drpeterosborne.com/
Facebook: / doctorpetero. .
Pinterest: / docosborne
Instagram: / drosborne
Twitter: / glutenology
*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.

[@jessw6617]

At 14 years old my son had the teenage triple vaccination he was so sick for 10 months throwing up several times a day and could only stomach veggie juices he could barely walk with help. $28,000 of IV Vitamins later he could go back to school at a slow pace. We are five years on and we can see health as it was just around the corner. Boosting the immune system is a much better way of dealing with the nasties of the world than any injection.

[@zionconnor7090]

@Theo Idris yup, I have been watching on flixzone for years myself =)

[@diegokeegan5420]

@Theo Idris yea, I've been watching on Flixzone for months myself =)

[@gracegwozdz8185]

All this vitamins and all you need is a parasite cleanse!

[@knyckname3295]

​@@gracegwozdz8185fenbendazole panacur-c 750 mg a day for 3day. Nitazoxanide (Alinia) 500mg twice daily for 3 days. Ivermectin dosage based on the weight of the patient, one dose once a month for 3 months.

[@ninidini8001]

I’m so sorry this happened to your son, I hope he is doing better now x

[@StitchingWithLove]

The last 10 minutes alone are pure gold.

[@lifeiswargodisall7415]

Your videos are saving my life. Your first video to be discovered was about oxalate toxicity. My gut and overall health was a mess, but now I'm getting better and better. Thanks a lot.

[@rdance3]

I talked my doctor into running a full B complex panel to prove that I had Biotin deficiency. I didn't know that the panel had all B vitamins except Biotin. The results came back and my B12 and B6 were high. I hadn't been on supplements for 7 days prior to the blood draw. At the visit, the doctor didn't know what to think and just told me to reduce my supplements. I take very little B12 and B6. I had to educate my doctor that this actually proved my point about Biotin deficiency, since PCC enzyme of the transsulfuration pathway, requires Biotin.

[@AnnaMaria-zm8cv]

I had low normal and high folic acid. I stopped (high dose) supplementing a week before the test. This was serumtest. I also took HoloTC and my active B12 was high (because I took it as mouth spray so that explains high active B12 as my stomach didnt bind the other forms in my stomach to become activated). My dr said I still possibly could be deficient on B12 because supplemented vitamins can stay in bloodserum for up to 5 weeks and this could not rule out deficiency. Just to say to you, a serum test doesnt tell much except if it shows deficiency then you absolutely are deficient it cant proof much more on its own. I need to take MMA blood test to rule deficiency out. Despite I took megadose (50000% RDA as mouth spray) B12 my serum levels were low normal. Be wary of symptoms if you indeed stop supplementing, the high levels may still be from the supplement you took and you still could be deficient because you have issues with activating B12. I choose to not stop and continue and test again in 3 months when I slowly reduced supplementing. Because I feel better taking extra B12 and dont want to risk my health stopping it and suffer deficiency. I keep mega dose 2 months and then half it in month 3 and 100% dose in month 4.

[@rdance3]

A MMA is definetly a good metric in determining B12 deficiency but it too is not definitive. It really needs to be performed in conjunction with a Hcy test. Serum Folate is usless. It doesn't measure active Folate. I retired due to extreme metabolic fatigue, at age 53. My methylation was all screwed up. My doctor had me on double doses of Folic Acid. My Folate and B12 always tested normal. If Hcy is high and MMA is high it could be either low active Folate or low B12. If Hcy is Hcy is high but MMA is normal, then it points towards low active Folate. But here's the kicker. Low Biotin can mask a MMA test result because Propylon CoA Carboxylase, that makes Methylmalonice Acid requires Biotin as a cofactor. I have injected myself with B12 for 15 years and family members for 5. It is true that certain supplements linger in blood serum but by now way do they linger for 5 weeks. I know this for a fact. More than once I have been tested by one specialist that was unexpected and I didn't go off supplements, so I retested less than 2 weeks later, after proper preparation, to find more believable results. When I retired, I had 5 specialists and was on no less than 20 prescriptions. I'm the one who figured out my poor methylation, not my doctors. I was knocking on death's door when I did. I was overweight, depressed and listless. I started my own procol based on my own research and understanding of metabolic pathways. Since then, my fitness gained to the level that I was asked to compete in a Men's Classic Physique competion. I got down to 9% bodyfat by DEXA. I also threw 16 prescriptions away. No thanks to any of my doctors. Like I stated in my original post, I asked for the B vitamin panel and when I got the results, the doctor couldn't even understand the results that were clear to me. BTW....Low B6 can also mask MMA results. @@AnnaMaria-zm8cv

[@AnnaMaria-zm8cv]

@@rdance3 thank you for this info by experience. Like you I am also doctoring myself because no doctor does something to feeling miserable. I learn along the way. A lot. Because I am the only one who feels whats going on inside and how I respond to things. Its all trial and error but never putting my life at risk of course.

[@Padraigp]

​@@AnnaMaria-zm8cvhad similar issue with my son when he had his blood test he hsd been taking supplements they didnt a damn

[@shahfarooq8106]

Hi dear doc Listening to your videos made me believe that going to doctors is more dangerous than avoiding them with exceptions.I have now been in a position to see to health problems of my family members myself supplementing them when required and by God's grace we are all feeling better even feeling younger . Thanks a lot

[@captainshivers]

Ah man you totally nail it with the CV. Great stuff and fully explained. Best Info on the net. Thank you so much!

[@hopesmith2185]

I have watched countless videos, and have found nothing equivalent to this type of health education.

[@quantumada]

Thank you soo much Dr Osborne - i am a follower of your videos, and bought your book too. I changed my diet - I am gluten and sugar free now and feeling much better 😍

[@DrOsborne]

Wonderful!

[@robynunthank6960]

Truly wonderful course. Well explained and presented. Thank you.

[@christwisted]

Another top presentation 👍🏻👍🏻👍🏻

[@jessw6617]

Brilliant lesson today, thank you, thank you Doc very appreciative

[@zoemicha6163]

So many great informations!!! Every time you open our eyes doctor!!! Thanks a lot

[@maryphillips9837]

Great info. You’re the best🙏

[@LB-sw2km]

Thank you again !!!! You are the best !

[@sharonlasper8999]

Absolutely FANTASTIC 😊

[@elsbethgross4675]

I love your videos, they are so informational. I m from Europe, and they believe in a good diet, but no extra supplements to help along. Also the doctors here in the states, don't get no information about healthy living without Meds. Your videos are great teachings. Thank you.

[@marylene836]

Thank you Dr. Osborne. You're always so great!! God Bless.

[@aribella6913]

Every video is GOLD!

[@susancollins337]

Thank you so much for this very important information 🙏❤️

[@marionmann8341]

i just discovered this channel. Excellent!!!!!!!!!!!

[@jeanne8380]

I salute and Thank You Dr Osborne. Been following you for a few years as I'm very interested in Functional Medicine. Your videos are awesome - very well explained, clear and packed with useful information. Learn a lot and clarify things I have difficulty to understand. Also Totally agree with you regarding the vaccine. As a T1 diabetic, i'm considered at high risk but with good nutrition and supplementation, sleep etc I'm actually healthier than some people. Thanks again and keep up your great work.

[@katedumitru4481]

I absolutely love your lectures and your explanations on CV. Absolutely spot on! This is the real info. Thank you, doc!

[@neritesorero1541]

Thank you Dr. Osborne, you are so great. God bless you more for your expertise and generosity of sharing your brilliant research works.

[@brankakrickovic8799]

Thank you dr. Osborne, it is always a pleasure to listen to someone who did sincere research, knows what he is talking about and care for others ❤

[@aquasoulstar3286]

Thank you so much! I was diagnosed with RA and this helps so much❤️ also just went grain free and my inflammation has went down dramatically!

[@adventurecyclist8473]

grain free also. Waiting to see good results

[@cherylstoyanov5921]

Great videos, watching from Bulgaria,

[@horstraedel9010]

Awesome, Dr. Osborne, thank you, it's very helpful!❤🇩🇪

[@rdance3]

If Folate status in good, another cause of high B12 is having low Biotin. Propynol CoA Carboxylase of the Transsulferation pathway, is Biotin dependant. In this case, B6 will also be on the high side.

[@mg4241]

Best doctor ever ❤

[@sarahwalker3154]

Your awesome Doctor thanks sooo much 💕

[@marieelainecarter6335]

Thank you Dr. Osborne l follow you regularly from Italy.. Grazie mille

[@joetodd7944]

Joe UK keep up the good work doc

[@aruppanda6399]

From India Great Informative & Educative

[@LearningGrace]

Thank you for such a candid and fair discussion on the jab. My husband was pressured to get it. Ever since, he has had tingling in his hands. My son and I did not get it. When my husband and I went to see a special independent movie in a nearby large city, I was turned away because I didn't have my papers (a card that proves you had the shot). The movie we wanted to see was 'Unsilenced' -about tyranny. So ironic right?

[@shanaspooner]

Will you do a video on Mast Cell Activation Syndrome?

[@EstherLilyW]

I had to stop multivitamins while on chemotherapy because the folate was being inhibited from growing the tumor in my chest. Please please indicate speaking to Oncologist before supplementing DURING chemo as you can mess up your treatment! I took supplements AFTER chemo therapy and in complete remission. Hair grew back and not growing tumors in my chest now. I had Hodgkin's Lymphoma in 2017.

[@EstherLilyW]

@@caracre I didn't have radiation. Best to speak with her oncologist, tbh.

[@dottydot8058]

very usefil info wwhich now makes sense of my conddition will be taking plenty of folate from now on

[@giannan4953]

You rock Dr. Osborne.

[@NoPronoun224]

Covid data at the close is perfectly reasoned and well presented. Thanks.

[@v.annabonac2913]

Thank you!

[@selinabrookes8045]

The last 10 mins :) yes dr Osborne EXACTLY!

[@Cushla73]

Watching from New Zealand thank you

[@donnazukadley7300]

Nurse here seeking answers from my mandated vacc1ne injuries

[@scorpiotigerstarot]

Watching this and you answered my question at the end. 🥰 @peterosbourne went to the new Internal medicine Dr this week. Asked for a nutritional panel, he looked at me strange, ordered blood test I JUST had done last week, threw more BP meds at me, gave me a script for the B1 (I told him I just bought), prescribed me folic acid ( bout to go look to see which one) and walked out. ☹️ So tired of these "doctors". BP didn't act up until I fell in the bottle for two years. I am determined to fix myself. I'm not taking them meds they give me. All them BP meds they give me make me feel like I'm going to have a attack. And I told him potassium makes my heart flop. Checked the meds he gave me... It has potassium in it! 😤 Thank you for your work! The B1, B2, & Vitamin A I started this week made me feel better INSTANTLY! THANK YOU SO MUCH! 💚✨

[@madhavidasari8302]

Thanks you sooo much forr the wealth of info given doc ❤. I am becoming toxic to folic acid pretty quickly, but not absorbing iron. Will try the methyl folate and see. MCV slightly higher than normal. B12 is normal. Is it safe to supplement with B6 since they say minus B6 and B9 is better.

[@sharonsvoboda2445]

How does one have both high homocysteine and low glutathione (on organic acid test)??

[@user-sg7bi6cf7o]

I am K V K Vsudevrao from INDIA .Thank you for the classes

[@yourenough3]

First id like to say how much i appreciate dr osbornes content. QUESTION 💥💥💥 Could dr osborne do an in depth video about sulphur / MSM and how ots so needed. 😊 thanks

[@danatalia714]

Thank you

[@Wheatfree]

Hi, Dr. Osborne. I’m watching from the UK. Just to say I appreciate your work and I’m enjoying your videos -new sub 👍🏼 P.s new Dx of IDWA & folate deficiency. Advised to purchase OTC folic acid and eat more fortified cereals.. 😒Granted, my experience is only of one medical doctor but it does still show some lacking around nutrition over here too. I do worry about this and patients who are unable to research things for themselves, esp as nutritionists/dieticians are not routinely referred to (this is just in my experience as a nurse)

[@annettewebster296]

Can you address ridges in the fingernails.....been looking for the answer? I do have MTHFR 1298 & 677. Thanks!

[@Kaiyen9]

I knew I felt off after the V - this explains everything

[@heavychevy4616]

thank u sir

[@johnrobertson1808]

Great video! Definitely eat your greens! B9 Folate, Spring mix salad is high in B9.

[@trentbusta1]

Liver , beans and deez nuts!!!

[@trentbusta1]

Liver , beans and deez nuts!!!

[@lindawhite6540]

Hi Dr Osborne Linda White from Florida

[@jimmyg3855]

Do you have any videos on the PON 1 mutation? Along with Mtfhr mtrr

[@bosman6456]

great video. does daily baby aspirin negate my 400mcg methlfolate ?

[@rosssundberg5510]

What if you react to methyl b complex ?

[@Anne-kb9hd]

Lethologica, the tip of the tongue phenomenon, or Lethonomia, (the inability to recall I.e. of some Actress you’ve seen in Movies over the yrs.🙂😉. Thanks again for your Brilliant Research.

[@cyndi5510]

God Bless 🙏🏼🤗

[@sharonlocke9096]

Thank you so much for this lesson on folate I have made notes ànd will listen again Iam very low on iron "anemic". if possible please do a video on "Sjogrens" I haven't seen anything on it. 😢 47:41

[@heide-raquelfuss5580]

Vit D Vit A Vit E This are deficienties probably in Sjorgen syndrome.

[@mjh4868]

Hi Dr Does your Folate for sale Have that synthetic folate you suggest not to take? Or is the DFE the non synthetic form as I see it is also in your brand and my other brands. Thanks much ..Your sharing your wisdom is helping many of us

[@DrOsborne]

www.glutenfreesociety.org/shop/health-focus/energy-focus/b-vitamins/5-mthf/

[@jenniferkilleen9642]

I live in Cape Town S.A, I think your talks are amazing easy to follow, easy to understand. Im 83 follow a healthy diet and have great gut. But slight nuoropsthy in the feet, and Tinitus I suspect it could be the result of cell phones.good show.

[@farzanehjafari1242]

A Homeopathic said mixture of olive oil and Basil oil is good for tinnitus

[@donnazukadley7300]

A lot of us got tinnitus from the C 💉 jabs

[@donnazukadley7300]

​@@farzanehjafari1242I heard taurine good for tinnitus too

[@suzp8627]

What is and adequate LAB level for F0lat3 serum & RBC ⁉️💜

[@tanatruong7501]

Good morning Dr. Peter I have been blessed to have found your channel. I was want to ask you my son had a blood test called micro nutrient testing and found out that he was low in inositol. I was wondering how much can he took and how long can he take it, thank you.

[@tanyawieczorek6603]

Did he start taking it and how is he doing now?

[@rdance3]

Low Folate can reduce SAMe production. SAMe is a methyl-donor to COMT which processes Dopamine. Dopamine too high will cause neurological symptoms.

[@Jicwfs]

New symptoms of eyes crossing and uncontrolled cant do it myself it’s on what is this it’s scary and I’m afraid of hospitals lasted about 30 seconds they have done some labs, but they always come back normal or borderline

[@mistersir3020]

You can be deficient in any of the B vitamins if you don't have a healthy gut microbiome. The gut microbiome feeds on your vitamin D so you need to have enough vitamin D in the first place. (Look up Dr. Gominak.) In any period of high stress, the body uses up a lot of its vitamin B stores. That's why stressful evens, physical or mental, can trigger vitamin and mineral deficiencies to surface and not go away anymore.

[@joanneg665]

That makes total sense

[@blessedgraceindeed]

I found out with swab test I have two mutation...white blood cells were low...so I intuitively ✔️ since serum test said ok..mcv was high..

[@vickyjackson3131]

Hello from England. My mum lives in Peru and she has kidney failure on meds for HBP she often gets anaemic would you recommend that she takes B vitamins sublingual or just B12 and B9. Thank you and God Bless you🙏

[@gracegwozdz8185]

Your mom should get rid of parasitic infection causing anemia in the first place.

[@Mentabolist]

Subcutaneous injection

[@marjoriemurray4381]

Dr. Osborne, I was told that my cells were not fully taken in folate (

[@Mentabolist]

Subcutaneous injection

[@AHaffejee]

Hi from south Africa 🇿🇦

[@alanaatchison9249]

Can a folate deficiency cause panic attacks and anxiety?

[@DrOsborne]

yes

[@tanyawieczorek6603]

​@@DrOsbornewow, didn't know this either

[@4510hald]

HI FROM DENMARK

[@sophieamirian6726]

DOCTOR OSBORNE ❤YOU ARE ONE TRUE DOCTOR WHO CARES TO HELP AND HEAL PEOPLE ❤ GOD BLESS YOU

[@godofallgodswithnoothernam920]

Love u Osborne

[@AA-en3qv]

Can seed oils cause sensetivity to the gut such as olive oil or mct oil or sesame seed oil

[@rdance3]

Sulfasalazine also inhibits DHFR. I was on MTX and Sulfasalzine so my rheumatologist had me on 2 mg of Folice Acid. It caused me to have to retire due to extreme metabolic fatique.

[@gracegwozdz8185]

Rheumatologist knows nothing about vitamins. He can't even distinguish bioavailable from synthetic!

[@danaking3592]

Most people have problem with folate acid, best only suppl with FOLATE!

[@rdance3]

Methyl-Folate@@danaking3592

[@kathleenmcgrady682]

Please can you answer my question I was told I was not making vitamin B12 I had t been stirring it from my food for awhile the doctor advised me I should take an injection now for life long I seen a doctor who specialist in vitamin b 12 deficiency I asked him if before I went on the injections could I change my diet eat more liver meats excetra he said I wasn’t able and I couldn’t get it out of my food as I wasn’t making the enzime that makes the vitamin b 12 anymore I took the injections now the doctors have stoped them I was okay for awhile but now I think I’ve lost the store of my vitamin B 12 and not making it I’m quite unwell and the doctors are not helping me I’ve tried to get there help and I’m not getting help I was sent for heart examination as I had a drop of blood presure or don’t know I thought I’d had heart failure I did think I was going to die the hospital I phoned they just kept asking loads of questions no help I felt I was to sick breathless to stay asking fir there help they where not helping I put the phone down as I was needing to lye down I was poorly all night I took some salt water I didn’t know what to do I got threw the night but I don’t know what happened I’ve had no more help offered like I’m making it up for attention I’ve stoped asking for help it’s far to upsetting they are treating me like I’m a fool don’t know what I can do to help my Heath I read things like your videos please can you give me your opinion on if I’m needing the injections or your take on what’s going on with making vitamins

[@linda7279]

Look into digestive enzymes and eat your liver or take a beef liver supplement until someone more qualified answers you....God bless 🙏🙏🙏

[@michaelayalaathotmai]

Try nose-to-tail Carnivore for 90 days with Intermittent Fasting. Get the best quality ruminent meat. Think Beef, Butter and Eggs (with runny yolks to get the benefit of the fats). Counter-intuitively, you will most likely spend less money on food, be more satiated, and will really start cleaning your body and cells from the inside out. It will give your body a rest from a multitude of plant toxins and anti-nutrients as well as toxic processed foods and substitutes for food that are called food.

[@rachelarc8837]

Why does folate with B12 cause ovarian cramps throughout the month, boob pain, acne? It great for energy but it causes these issues for me. I’m trying to get rid of vestibular migraines, but hard to keep up cuz the hormonal changes

[@Tk-iz2ws]

Heard it was a need for B5 to stop headaches. Not a lot. Start small and increase slowly till they are gone. TO MUCH IS BAD TOO LITTLE IS BAD.

[@gracegwozdz8185]

Excess B12 most often is due to parasitic infection out of control. Address this with Hulda Clark parasite cleanse.

[@donnazukadley7300]

Increase zinc?

[@lulum6015]

Whats a best and brand name B/Complex can I buy?

[@DrOsborne]

Here you go www.glutenfreesociety.org/shop/health-focus/daily-wellness/b-complete/

[@alexac921]

@@DrOsborneIf I have trouble with absorption due to GI issues, is this still a good option for me? I want to order this, but I hope I would absorb it. 😊

[@andreaarias2085]

Riverside California

[@user-oc5xt7nl7e]

You mentioned that the cracked corners of the lips can be a B2 deficiency. I've heard that taking more B2 can help those people with the MTHFR SNPs and that people with MTHFR issues, really just have low B2.

[@ingramwedderburn6919]

Thanks much Fr Osborne, your in depth explanation make your presentation so educational❤

[@Maria-iu3ed]

Hello, your multivitamin seems to be a very good product, with balanced quantities of vitamins and minerals!!! The problem for me is the iodine, as i have hashimoto and my doctor adviced me not to supplement iodine.

[@gracegwozdz8185]

Maria, your doctor is wrong. Any thyroid condition benefits from Iodine supp. Except you need to educate him on a root cause of Hashimoto: parasitic infection.

[@Maria-iu3ed]

@@gracegwozdz8185 Hello! Is it due to parasitic infection? Wow! Here in Greece endocrinologists say it's autoimmune disease, and they don't know what causes it!!!

[@danaking3592]

@@gracegwozdz8185 but doc not test or treat!

[@VB-oz5cb]

@@Maria-iu3edalso if you are going to do a parasite clense make sure to check the lunar calendar when to start and to finish.

[@TheRagbags1]

I’m heterozygous C677T & A1298c Ehlers , painful neck head depression . Folate bloods high with Macrocytosis I believe pooling of folic not in cells & not realistic

[@debbiecoburn9087]

Folate vs folic acid what is the difference

[@tomunderwood4283]

24:00 minute mark is folic acid vs folate

[@tonicooley8484]

💜

[@blessedgraceindeed]

I found out at 64

[@godofallgodswithnoothernam920]

The graphine is off set I think by human complementary factor which binds the gold nano particles changing the zeta potential to the antithesis of how graphine oxide works - this in-turn inactivates and deactivates the collidal graphine oxide - via colloidal gold - which I drank like a litre of in around a week no adverse effects Also I take about a teaspoon of EDTA a day for months and zeolites no adverse effects yet beenficial effects

[@medicinefuture]

folate decreases homocysteine level because of the conversion to methionine, and homocysteine is one of the sources of glutathione, so why you said that folate deficiency reduce the level of glutathione, maybe the reverse of what you said will happen?

[@RAO.NUTRITION]

Cysteine is one of the sources of glutathione, not homocysteine.

[@beaware354]

Yes, you’re right. Homocysteine is a marker for inflammation.

[@shahfarooq8106]

❤❤❤

[@dinomiles7999]

Bryan Johnson Blueprint, Ai will soon take the guess work out of it and all gurus and snake oil salesmen will soon be gone. See you in 2500

[@sheilaringer5588]

it this what causes p ernisa anemia

[@tanyawieczorek6603]

Pernicious? I think that's low B12...

[@nancyj795]

Lentils, bro.

[@billhemrich559]

Why would I have high folic acid without taking anything

[@tanyawieczorek6603]

Did you figure this out?

[@billhemrich559]

@@tanyawieczorek6603 no

[@user-we1te4sd2o]

Anything that alters the body's natural state is a drug. That's what I was told. Still alcohol alcoholic, I have six years sober!🙏🙏