Answering Your Hormone Therapy Comments |

[@ThePCRI]

Video Timestamps: 0:46 What is the difference between first and second generation hormone therapy? 2:20 How does hormone therapy affect libido and potency? 4:23 Are penile injections the next step when Cialis/Viagra don't work? 5:30 Can hormone therapy exacerbate penile shrinkage? 6:41 How effective is hormone therapy against prostate cancer? 8:53 How soon can the results of hormone therapy be seen on a PSMA scan? 9:47 How can couples anticipate and handle issues that may come with hormone therapy? 11:16 Can hormone therapy cause Alzheimer's? 13:56 Can exercise combat cognitive delay? 14:34 How often is the dosage of a hormone treatment modified? 16:46 Is any one hormone therapy superior to the others? 17:25 Can a patient with resistance to one treatment switch to another? 18:37 Is weightlifting essential for patients on hormone therapy and weight loss drugs? 19:54 Are oral hormone treatments best taken with food? 20:47 How can hot flashes best be mitigated? 22:35 How can a patient access hot flash treatments? 22:55 Can taking estrogen on top of androgen deprivation cause additional side effects? 23:27 What is the process of getting prophylactic radiation like? 24:53 How can breast enlargement be reversed? 25:23 What causes joint pain as a side effect? 26:18 How can patients handle the mental toll of dealing with side effects? 28:05 Can diet changes help treat emotional side effects as well as physical ones? 29:24 Alex's conclusions

[@frankcedrone5544]

@ThePCRI you will lose interest fast. Can't get a full hard on. If I could do it over i would do surgery and remove prostate. This site makes it sound good BUT IT ISN'T. THEY TRICK ME . PLEASE STAY AWAY 🙏

[@Skwarek-wp8dc]

Skip the BS ... do lutetium ...

[@jmG8RS]

I recently turned 63. After my yearly physical, my PSA was 45. After having an MRI and biopsy in April a couple of spots in my prostate were found and my Gleason scores were 9’s and 10’s. Had a pet scan done next and no metastatic disease was found, I was originally going to go with surgery but after doing a lot of research which included watching a lot of your KZbin videos, I decided to go down the radiation path started in June with Lupron injection and soon followed up with Zytiga. Did six weeks of radiation and two weeks ago had my HDR Brachytherapy . my PSA is now at .05 some side effects have been hot flashes and not sleeping well. I have always lifted weights throughout my life, but after watching your videos, I got a little bit more intense with lifting and improved my already good diet a bit more. Because of your information I feel this journey I am on has not been so bad and to you, Dr. Schulz and Alex and all my Physicians I thank you there is hope in winning the battle!!

[@franzie4158]

OMG! I’m on hormone therapy and for the past 3 months, I’ve been suffering from excruciating joints pains, special on my hips and knees. I brought this to my physician, she only gave me vague answers. Glad to hear that’s cause by the treatment.

[@leonardola9161]

I have the joint pain Fatique Hot flashes Sleep depervasion

[@EdWeibe]

@@leonardola9161 I think the sleep depervasion will ease off if you take your med in the morning instead of at night. (assuming you have a pill)

[@leonardola9161]

@@EdWeibe i had the 6 month shot

[@brockjennings]

60 y/o with a Gleason of 4+4 and PSA of 18 when diagnosed about a year ago. I went on ADT (Leuprolide & Casodex) last May. My PSA is now at 0.2 and testosterone has cratered to 5. Going the IMRT and brachytherapy route of modality next. I count myself fortunate to only be suffering from libido and hot flash issues compared to the other side effects one can get. I'm a believer that exercise is the key that helped mitigate the onslaught of the other negative effects of hormone therapy. I road biked for the past 35 years, which helps keep my cardio and endurance up. Also, purchasing a Bowflex during the pandemic has helped with resistance training to this day. I'm on a Mon, Wed, Fri cardio and resistance on Tue, Thu, Sat routine, which has helped me maintain muscle mass and kept my weight within +/- 6 pounds. Gents, please try to keep up on the physical activity and try to remember your goal is to convert fat to muscle. Best of luck to all in this fight!

[@schmingusss]

Is your pc confined to the prostate?

[@brockjennings]

@@schmingusss Yes, as of my PSMA PET, pelvic MRI and bone scan last Feb-March

[@daveh5605]

I'm 2 yrs into ADT and it's not a joyride by any means , my PSA has been holding at .04 now for 2 yrs and that's the one thing that holds it together for me. After all I've been through , 28 weeks of radiation and all that comes with that , the Hot flash I can deal with, the fatigue is the worst. I am not overweight and have been lifting since Dr. Scholz first said this. 1 more year of eligard and I can put this behind me hopefully . I encourage anyone who is on ADT to get a gym membership. Thank You Dr.Scholz and Alex for all the great advice.

[@KDean22]

SHUN ADT... KILLER TREATMENT. MY PSA IS 264 AND I REFUSED IT

[@daveh5605]

@@KDean22 This is still a free country , do what is best for you.

[@denissparks2133]

Have never heard of 28 weeks of radiation!? I had ten weeks (44 treatments) and I thought that was a lot. Wishing you all the best.

[@daveh5605]

@@denissparks2133 lol my bad it was 28 days everyday.

[@billhyde6875]

Hi, I can’t tell you how much I appreciate your down to earth, informative videos. I have learned so much, which has helped me, and my friends and relatives, to understand, and be comfortable with my condition and my treatment. Thank you.

[@denissparks2133]

SO appreciate these videos! You have provided 90% of the useful information I have received from the medical profession and that includes my GP, Urologist and Oncologist combined.

[@RobertLupo]

You guys are a blessing, thank you so much. I'm on 4 month Eligard, havent noticed fatigue, but frequent hot flashes. I work out 6 days a week and I guess that helps but the hot flashes are killers.

[@marmotsongs]

I have been on dialysis for a combined total of 10 years starting almost 40 years ago (2nd transplant has been working for 10 years now). I found out on my own 40 years ago that vigorous exercise would negate nearly all the effects of dialysis and allow me to live a nearly normal life. I tried to get the doctors interested and to study it over the years, but they just looked at me as an oddity for being so active. I'm glad to see that it is now recognized- though apparently not by everyone. When starting ADT, my doctors might have mentioned exercise in passing once. I am so glad I found out about exercise's ability to counteract so many side effects of illness and treatment.

[@Vincent50]

I found out I had prostate cancer a year and a half ago at stage three a Gleason 7. I was too shocked! Me with cancer? My PSA was 3.65 when my Dr went over my blood test. I had the mri then the biopsy and as a present for my 68th birthday in late August it was confirmed. I had the PSMA CT Scan and thank God the cancer didn’t spread. In December I got my first shot of Eligard. After a few weeks hot flashes started. I had 44 treatments of radiation that didn’t really bother me until after treatments. My skin breaks out in rashes periodically and the crème I use which my dermatologist ordered keeps it tamed. I have to up my exercises and I can tell the difference in my legs too the way they feel so add in my sciatic and it can be bothersome. Bouncing back and forth with my diet but I’m determined to get it right. In June my PSA dropped to 0.07 which I am so happy. I also got my second shot of Eligard. This coming December I get my third shot and will do another PSA test. My sex drive is almost 0 but I can still get aroused and though not for a long time. I haven’t tried Cialis or Viagra yet. Hot flashes hit me but doesn’t last long. Overall I’m feeling good, still working, exercise, and enjoying life praise God. Thank u for all the information because you’ve helped me with making my decisions. Keep them coming.

[@GregSr]

I'm 71 now. The VA has been very solid in supporting my medical issues. I was diagnosed with prostate cancer about 20 months ago. I chose the radiation and hormone therapy. No regrets but the side effects are hard to deal with. The three month hormone was injected into my stomach fat. Don't know why, but that shot was VERY painful. During the shot, I muttered a variety of vulgarities. After radiation, my bladder capacity was reduced. The hot flashes were frequent and strong. My libido is gone. Don't know if it will return. Mentally, my attitude about life in general is suffering. As the country song says, "my give a damn is busted". I try to shield my wife from my bad attitude. She has been a strong supporter. She deserves better. Compared to surgery, I still believe I made the right decision. My oncologist agrees. My most recent PSA reading is 0.20.

[@TheRm65]

I sympathize with you, Greg. Although you can't do anything about the painful injection or the reduced bladder capacity (so far as I know), but you can control your attitude to the situation. Pain might be mandatory, but suffering is optional. Right here, right now, you're alive. Make the most of it.

[@user-qj2wb7ne4e]

Thank for this particular session. You continue to fill in the gaps that enable me to discuss treatment strategies with my doctors. Having been on a Lupron 6 months and completion of 28 sessions of IBRT I have found that a specific diet with emphasis on adequate amounts of protein has produced positive effects. The 5 day fasting mimicking diet has effectively helped me lose 10 pounds and helped me regulate my diet and manage cravings. During three connective months on the diet I did not experience hot flashes. Quality sleep also mitigates fatigue to some degree. Low dose Gabapentin at night helps sleep and tends to eliminate hot flashes.

[@rwally3able]

THANKYOU!!!!!!!!!!!!!!!!!!!!!

[@sheeplady2e]

I shared this to a support group for women & partners of prostate patients and I hope that they watch all teh videos

[@jjbsnak95096]

At 14:34 you mention a weight training protocol that you were going to link in the comment sections, but I don't see it there. Very helpful video, as always!

[@ThePCRI]

Simple Weight Training Protocol: shorturl.at/Da9Bn

[@kinophil]

@@jjbsnak95096 I agree. don’t see the link either (and I feel like it’s been promised before). I really rely on PCRI videos. A specific recommendation for a weight training regimen would be invaluable for those of us on ADT who can’t afford a private trainer.

[@cherylsteele2310]

My husband who is 82 is currently being treated for prostate cancer…..listening to your programme I am finding out information that no one has explained to us….especially all the side effects of hormone therapy…we have a very strong marriage, and we are trying to cope with all the changes that are happening…one day at a time….but it would be so much better if we were informed before hand of all the different challenges we would face…but thank you for this programme it helps a lot….greetings from Cape Town S.A. 👍🙂💕🐾🐾🐾🐾🇿🇦

[@timkbt]

I was diagnosed with prostate cancer back in 2017. I was given one year of Lupron and then six months radiation. My primary physician missed a test where my prostate cancer had come back and was starting to rise. Since then I’ve gone back on Lupron but couldn’t handle the side effects so I am now seeing another medical group that’s great. I’m actually seeing the director of the entire oncology program. First thing he did was have a PSMA scan done and then also got me approved for a pill form using Goravex. I’ve only been on my new treatment for two weeks now, but I have no side effects at this time. Lupron is considered a very harsh treatment. There are much better medications available now. I go swimming four times a week and also do weight training three times a week. That really helps keep the weight down and my energy levels up. A good diet getting on the right medication and exercise program is essential for the treatment to be sustainable.For most men the side effects, like hot flashes, and fatigue are hard to deal with. The good news for me is going forward is there no more shots that I’m going to be put on. It’s all going to be in pill form the half-life for the pill form drugs is only one day so it only takes a week or two to clear the drugs from your system. If your husband is on Lupron, then I would really suggest that you get him on one of the pill forms like Goravex. The doctor in this video mentioned that Xtandi has bad side effects and caused breast enlargement. I hope this helps.

[@TERRY-cb2ku]

I urge all men to join this blog to get the best up-to-date information available on prostate health and treatments.

[@lbaker9625]

I’d go one step further and encourage all the men listening to these videos to consider donating to PCRI. I am not a representative of the organization, but I can tell you it takes money to put these things on.

[@jondon9963]

@@lbaker9625 Agree, I donated after learning so much from this treasure trove of information on PCRI.

[@ACTIVEPAIR]

Thankyou. I’m still going with Natural Therapy and avoiding Standard of Care for my 3+4=7 locally advanced PCa. I have a 2nd MRI next week so have a bit of ‘scanxiety’ as this will be 1 year after the one that diagnosed the cancer pre biopsy. I had a 2nd opinion from a different NHS Oncologist last week and she really wants me on ADT now but I said I want the result of the MRI before even considering that!

[@graigirwin1173]

I too am going with Natural Therapy. I'm also experimenting with Lucid Dreaming and trying to remove whatever energy blockage caused this "Anomaly" in my prostate to begin with. I'm thoroughly convinced that if I can address the root causes of my condition, at the Astral body level, the tumor will shrink, and abate. I know how this sounds a little esoteric, but there's more to nature than what leading-edge occidental thinkers think. When I first read a metaphysical explanation of why I had my condition (3+4=7), the information WAS SPOT ON. It described me to a tee. I was mentally blocking something BIG. I'm going to give myself 6 months to produce Definitive results. My back up plan consists of HDR, Brachy Therapy, Minimize Hormone Therapy, and half a normal dose for all medications, for 4 months. Fantastic information available upon request. What has one got to lose!

[@MyCousinGrandpa]

Another good video! Thanks Alex and Dr Sholtz

[@carladerenzy3674]

Excellent video as always. I've been on ADT's (Nubeqa and Orgovyx) for 19 months now plus 6 Lutetium infusions. My PSA down from 525 to 0.1. I am metastatic. 62. No new lesions for 18 months. Most cancer gone. I haven't had anything removed and didn't have chemo. I've had no loss of libido at all. Just as strong as ever. No erectile issues. I did have a lot of hot flashes initially, but find eating extremely well minimizes those. Biggest side effects for me are psychological. Anxiety. Emotional reactions heightened. So I have started taking Zoloft. It has evened me out with no other impact. I'd ultimately like to give hormonal holiday a try. What is your opinion on how the ADT's alter my body's future propensity to manifest cancer. I'd like to NOT stay on the ADT's for rest of life. I eat a Meditteranean diet, add sardines or salmon, and work out twice daily. High protein. Low carbs. No processed food. No added sugar. Only low GI fruits. I've managed to build quite a bit of muscle/bulk after 18 months and I've lost 30 pounds. Body fat is 8.2.

[@nickband2072]

Such good information again, many thanks

[@jaktao6044]

Fashion is key for good doctors

[@gunterk256]

Radical prostatectomy in 2013. PSA 0.03 for 9 years. When Covid struck and I had my first vaccination, my PSA started to tick up. A coincidence? By now I've had a total of 7 Covid vaccinations. 2 MRI scans showed no presence of cancer in the prostate bed. PSMA PET scan then showed oligometastatis in the right frontal pubic ramus. 4 months of ADT brought the PSA back down to 0.02. Though a few months later it started to climb again, reaching 1.49. After 1 monthly injection it is now down to 0.27, just had my 3-monthly dose. If the lesion is still present in January, I will request radiotherapy to get rid of this, I nearly said evil. I go to the gym 5 times a week. I have lost weight and am down to 58ks. Often I am just soooooo tired. Physically, mentally and emoitionally.

[@wayned550]

I was diagnosed 12 months ago psa 124 age 54 fit and healthy massive shock gleason 3 +4 locally advanced spread to my lymph nodes. Started hormone therapy in February injection in my stomach every 3 months plus abiraterone tablets 2 away plus prediserol steroid tablet. Finished radiotherapy 8 weeks ago 27 treatments. My psa a levels have dropped to undetectable which is great news. I work in construction so busy all day lifting materials I also do weights 2 3 times a week. Healthy diet cut out processed foods plenty fruit veg water un processed meat fish. My main side effect is I've blacked out twice in 4 months can't drive now but heart being monitored as abiraterone can cause heart side effects .I'm off these tablets until heart results come back hope this helps anyone🙏

[@wayned550]

Forgot to say dropped weight by 20lbs before Treatment started after reading about side effects. Managing to keep weight off but it's hard.

[@cmrjc74]

My psa started at 80 Gleason 9 just had psa it’s now 0.06. I’m on zytiga and orgovyx I’m also worried about the side effect of the heart because I had a heart attack in 2023 oct. may i ask what heart issues were you having

[@wayned550]

I didn't have any heart issues before treatment I'm having numerous test now to find out if it is heart related.​@cmrjc74

[@jazandriz]

Just started on it a couple weeks back. No testosterone baseline was offered at the time. I wish I had taken it so I knew what my target could be after

[@1958zed]

Informative, as always. Thank you! I wish you would have talked a little about the timing of starting hormone therapy. I had a radical prostatectomy that failed, and then I had salvage radiation therapy that also failed (PSA at start of SRT was 0.36; at nadir was 0.11; now it's 0.69). When I met with a medical oncologist, she suggested starting hormone therapy when my PSA hit 2.0 ng/mL. When I met with the urologist, she suggested waiting until metastases were present.

[@EdWeibe]

ok. recent memory issues, non recall etc., must be attributed to this. I dunno about crying in a movie, but man did I laugh so hard last night at a video I'd already seen 50 times. Laughed so hard I couldnt laugh any harder. THAT I needed. Depression is coming in and yeah maybe some sadness. Orgavyx patient here. T=20. The orgavyx doesnt totally wipe out T. It seems not as strong as other stuff I see on these comments, but it does knock the T down, which I guess thats all they want to accomplish. Physical effects are certainly present. Weight redistribution, as they say. I'd be embarrassed to ask for estrogen patches, but I do use a low running fan at night. Hot flashes will keep you awake.

[@frankcedrone5544]

Don't go radiation therapy with casadex meds, aligarh. Now 3 yrs later I can't walk and my mesh implant got entangled in my lower intestines. I wish I had the surgery instead. Thanks, frank cedrone

[@TOMMYSURIA]

Keto diet help me a lot 😊

[@shus5787]

Brilliant advice

[@lindamastropietro4429]

My husband sleeps a lot. He did gain a lot of weight. He doesn’t sleep well at night because of the hot flashes.

[@davidvasko6300]

Never mind the extreme hot flashes my lungs clogged up and heart problems. With the brain fog and losing myself with memory loss I just gave up why take it I would rather have the cancer take me and get it over with.

[@ricknowak4582]

Great comment brother! Best the reason why I do not take ADT with my radiation therapy. I refuse hormone therapy I don't believe it.

[@michaelmorris1424]

A couple of questions I wound have like to ask: There has been past research that indicated antagonists are better than agonists when it comes to testosterone recovery. Is this still considered true? If so, why do I see Lupron still prescribed and by prestigious institutions? Also, I have read many men complain that ADT reduces the size and circumference of their penis and said affect is permanent. These same men report their testicles return to their primal size as their testosterone levels return, but not their penis. Is this true? Dr. Scholz mentioned penile interventions that should be practiced while on ADT. What are those interventions (vacuum pump? injections?) and do they prevent permanent shrinkage?

[@HCSWombat1]

It would have been great if the topic of “testosterone recovery” would have been covered. Specifically, how long does it take, what does it look like? What are the options for improving or accelerating testosterone recovery upon the ending of hormone treatment

[@scottwillis5434]

Testosterone feeds PCa. You can get testosterone replacement therapy, but best done after waiting long enough to be sure the PCa is dead.

[@RobertLupo]

Excellent question, I was thinking the same thing...how long after we are off this stuff will we recover and what can we do to rebuild our testerone.

[@thomasflynt1764]

58 and diagnosed with 4+3, cT2a, n0 m0 and PSA was 4. I finished 28 treatments of external beam and I'm 5 months into a 7 month Lupron treatment. Due to a 4 month shot, a 3 month shot and my radiation schedule, it broke down like this. ADT 2 months before radiation started, 1 month during radiation and 4 months after the completion of radiation. Fatigue has been worse after the completion of the radiation. I need lots of sleep and I can't get hot or my energy almost instantly drops to zero. Now, the weird part. Libido is absolutely zero (at least when I'm awake) but I've had several wet dreams for the first time in years the last couple of months and even wake up with an erection or semi-erection. Hopefully that's a good sign for when this ADT wears off. Edited to add: Between fatigue and getting hot too easily, I don't work out with weights. And, even though I technically have a desk job, I walk anywhere from 2 miles to 4 miles every day at work as well as go up and down 2 flights of stairs numerous times while wearing steel toed shoes that are required. I probably have lost some upper body muscle mass but I've also dropped about 5 pounds since all of this started.

[@federico1974]

I am in similar situation Gleason 4+3 , PSA of 7, no mo. I had radiation to prostate and 6 months eligard ADT. After I finished the 6 months hormone treatment the side effects are much worse ,I have problems sleeping wake up several times at night to go to bathroom, very tired almost exhausted, pain in my knees that make noises , hot flushes. I hope this improves in the future. By the way when my 6 months eligard finished my PSA was 0.05 ng/ml was told it was good response to hormone treatment. Also I was todl that as my testosterone starts to recover the PSA is going to go up a bit.

[@hughtur72]

Fatigue and hot flashes have been a tremendous issue. Severe retractration is an issue as well. None of these side effects were discussed with me by my physician . I didn't make it to the gym today and feel guilty about 😢

[@marmotsongs]

I was told that soy can help with hot flashes. Soy contains phytoestrogens (particularly isoflavones), which are plant-based compounds that mimic estrogen in the body. These compounds may help balance hormone levels and reduce the frequency or severity of hot flashes. Foods rich in soy include tofu, soy milk, edamame, and tempeh.

[@francisclare5852]

I got over my hot flashes with soy milk.

[@EdWeibe]

there's an over the counter cream which contains all the ingredients to move some hormone levels around. I dunno the long term effects though.

[@mklee8908]

I was hoping this episode also cover the rashes caused by the hormonal drugs. Erleada and Zoladex. The rashes are large patches, and pimple like spots that progress to larger acne like spots with lesion or moles.

[@groove9tube]

I am always so hungry on ADT. Calorie restriction is something to consider to prevent the weight gain.

[@ricknowak4582]

When do I there aren't any studies on suicide rate with people on ADT!! No mention. My goodness for all the side effects you just mentioned I would think that many people would commit the terrible s word.

[@edwardkirby7679]

It stands to reason they would.

[@russellkandalaft1381]

Thanks Alex and Dr Sholtz you have helped me get informed with my hormone treatment. Way to much too life changing events. I am not looking forward to this.

[@Bill-6033]

I was not able to find the weight training link. Could you help with the link. Thanks

[@ThePCRI]

Simple Weight Training Protocol: shorturl.at/Da9Bn

[@RH-xd3nx]

Any studies on implementing Ozempic for adt induced weight gain? And creatine for strength and maintaining cognitive thinking

[@Lapohaus]

You mostly recommend hormon therapy as a 2nd line treatment together with surgery or radiation. Can you please advise whether it is advisable to go on HT on its own and monitor your psa b4 actually embarking on RT or Surgery. Would you recommend it for gleason 7,8 and 9 which have not metastasised.

[@ArtHorton]

Please advise, I am embarking on HRT, utilizing orgovyz, please advise what the weigh training protocol is. Thank you. You have been very informative. None of what you covered has been provided by my urologist.

[@BruceFoerster]

If the oncologist told you all the side effects you would never do it(ask me how I know)

[@user-qj2wb7ne4e]

Could not agree more. Doctors don’t seem to have time and, or the expertise to discuss remedies for the side effects of ADT. Diet, nutrition and exercise are not emphasized enough. We are on our own for the most part unless you find doctors as competent as Dr. Scholtz and company.

[@scottwillis5434]

See Dr. Mulhall's videos. He's a sexual medicine clinician who deals with the aftermath.

[@cmrjc74]

I’m on Zytiga and orgovyx and the side effects suck and I was just told joint paint and some fatigue nope

[@jondon9963]

Currently a month into 6-mos of Orgovyx. Being treated at MSK and surprised by their lack of information/support when it comes to ADT. I feel like I'm pretty much on my own. I was on the phone with a nurse yesterday and when I was speaking to her about my constant hot flashes, she basically said to suck it up and that there was nothing I could really do. There's never been any mention of Cialis or similar to keep the blood flowing. Luckily, the only side-effect for me so far has been the Orgovyx. Thanks as always for your excellent videos!

[@corgiowner436]

You can take - I think it’s megace-for the hot flashes. Otherwise a fan helps.

[@elbertnetters980]

12am- I'm just completing radiation therapy and before starting I had first hormone injection. I'm scheduled for a 2nd in a couple of weeks. What am I to expect after completing 6 weeks of RAD then jumping into hormonal injection again. What are side effects? What do I do next? ALSO YOU ARE RIGHT, there is no shared info.

[@davidwhitesell6144]

Please give me an example of a weight training program that you guys recommend. Thanks

[@dgre334]

youtube.com/@liveanabolic?si=-Mm5lNwxPcXMZIc8

[@ThePCRI]

Simple Weight Training Protocol: shorturl.at/Da9Bn

[@RobertLupo]

Consider joining a health club if you can. I belong to one and go to their fitness classes 6 days a week. The classes, for me at least, are a great way to develope the discpline to continue to work out.

[@truthseeker1959]

I took 5 shots of Eligard over a 12 month period. 7 months after my last shot, my testosterone STILL has not come back (

[@tnvol5331]

is it OK to go on ADT for just 4 months?

[@TOMMYSURIA]

Eligard with Parkinson's what a wonderful combination 😖

[@scottwillis5434]

See also Dr. Mulhall's videos, before treatment. He is a luminary sexual medicine clinician, and sees patients over the long recovery period, unlike e.g. a surgeon who has to keep their numbers up and may only see you at the operation. They just don't have time OR expertise in the issues that occur after you left their clinic. One thing he says is that injecting your penis uses an extremely tiny needle, like a mosquito bite.

[@jimchoff]

I have one, localized grade 4 tumor. No metastases. (PSMA PET and MRI confirmed). I plan on radiation and hormone therapy. My current urologist casually suggested 12-18 months of hormone therapy. On the other hand, Mack Roach is saying 4-6 months. How do I square these polar opinions?

[@user-qj2wb7ne4e]

My urologist and radiation oncologist were at odds on the duration of ADT. Clinical details led us to a decision to monitor my tolerance of the first 6 months of ADT. I have 4+3 with a high risk Decipher score thus the need for 18-24 months of ADT. At 81 and in good shape I am tolerating the side effects reasonably well. Hot flashes were non existent during my 3 consecutive months of the 5 day Fasting Mimicking Diet and has kept them at bay for the most part. Exercise is the best way to mitigate fatigue along with quality sleep. Resistance training and adequate protein intake is essential to maintain muscle mass. Your PSA level post treatment will dictate the effectiveness of the ADT. This will be one indicator of how long ADT therapy is administered.

[@ArtHorton]

Also after 44 radiation and 2 cryo treatments my PSA has continued to climb

[@kanwarjitnanda4897]

I have had severe arotic valve stenosis and I have got my valve replaced by Tavi. I am on hormone therapy for last three years. My Psa has been constant around .05. Mine was metastatic prostrate cancer FOR HOW LONG I SHOULD CONTINUE HORMON THERAPY. CAN I TAKE VIAGRA CONSIDERING MY AROTIC VALVE HAS BEEN REPLACED. PLS SUGGEST😮

[@qadeerwarraich7122]

I am undergoing treatment for my prostate cancer which as the the time of diagnosis had spread to the bones. Its been three and half years that I am aberarerone and zoladex. My waist line has increased. I experience pain in my backbone and ribs. What exercises can I do? I am now turning 63 in Feb 25

[@elbertnetters980]

Would you mind POSTING some of your replies to questions asked ??

[@leonardola9161]

After 28 rads what is the percentage for testasrone to come back and how long to come back ?

[@SheilsKinser]

My husband has a spastic bladder after radiation therapy. Is there something that can help with that problem? He is up every hour and more. We don't go anywhere that he doesn't have a bathroom available.

[@davegillteam]

My psa was 700 in February 2022. My weight dropped to 90 pounds in February 2023. On February 23,2023 I started Xtandi (Enzalutamide 4 Capsule 160 Mg. I was bed ridden 2 years!! Once I started Xtandi my psa dropped 88 the. 8, the. .33 then 0.1! It’s been there for over a year. I work out heavy weight since November 2023. I’ve gained 6 pounds of muscles and weight of 140 pounds. No side effects except little high cholesterol but my biggest goal is to keep working out 4-6 days a week 1 hrs 40 minutes each day. My goal is to never end up in the hospital again!!! I also changed my lifestyle to vegan diet again to 40 ounces of juice everyday!!! Btw I had prostate cancer since 2010. But I had become raw vegan until cancer came back in 2021! Now I’m back to raw vegan and some beans and vegetables cooked. My special smoothie!!!! Of God is Great. Thank you PCRI for inspiring me for the last 3 days. You guys gave me hope that prostate cancer is not a death sentence. Thank you! Thank you! Thank you. Someday I would like to give my testimony to you guys! ❤❤❤❤

[@leonardola9161]

My urologist said i needed 6 month lupron to shrink my prostate and the cancer tumor is that correct or could i have did different???

[@johndee48]

I cannot find the link to weight training program mentioned in the video.

[@ThePCRI]

Simple Weight Training Protocol: shorturl.at/Da9Bn

[@johndee48]

Thank you

[@johnpaoletti2694]

Confused as to whether I should take Zytiga with or without food … can someone clarify please??

[@wayned550]

I was told to take on a empty stomach then take your steroid tablet after food 1-2 hours later. That's my doctors advice👍

[@monarc78]

Isn't Hot flushes was one of the most common " big 3" ?

[@schmingusss]

I had a psa reading of 13ng/ml three months ago and now it is up to 14.2. I have lost almost 20 lbs from my 185 lb frame since then. I've read that there is an inverse relationship between psa and body mass. Could this be the reason my psa has increased?

[@leonardola9161]

What about 6month lupron and 28 radiations and trimix dont work. Would quadmix work ?

[@PilotJan]

At 25:00 painfull breast could be reversed simpelm, I noticed, with an amazon back massage rope reversed 180 degree for 1 hour every other day, it is gone, a wonder? You have to search a bit, this one had a battery pack, so you can move on in you work. Has any one done this, never heard of it in this space?

[@bobliening5783]

Weight training protocols???

[@ThePCRI]

Simple Weight Training Protocol: shorturl.at/Da9Bn

[@AndrewP-q1j]

LOL, After go’ogling Simmy Krotiel’s latest I noticed it had undergone revisions to add 4 ins. and even more using accelerated growth techniques, after 3 ins. more I feel so huge now, thanks

[@jeromemond-w1l]

How to control hot flahes on hormone therapy

[@ricknowak4582]

I am 71 years old currently on radiation for my prostate cancer and I refused all ADT! I am not taking that stuff! I don't believe it. You're much money is involved with hormone treatments? Unbielievable amount of money. Making the pharmaceutical companies filthy Rich. Please does anybody else agree with me. I guess from that comment you realize that I am very frustrated with the whole process of cancer. Doesn't seem like there is a cure at all.

[@scottwillis5434]

The amount of money involved is kind of secondary, isn't it? Going to take it with you? PCa isn't different enough from regular tissue to make it easy to kill; the doctors have to use the tools they have, which cause side-effects and damage, but (if needed) beat an early, painful death. Get enough treatment; avoid excessive treatment.

[@edwardkirby7679]

Just got my G8; waiting for PET. I agree! As soon as you're seated and locked in, the roller-coaster ride begins --and doesn't end!! You just keep going round and round. Limitless misery.

[@ralphcherry617]

Oh how I wish you had done this two years ago, when I started.

[@AntonyBramall]

does weight training increase testosterone therefore have the possibility to increase the cancer

[@elbertnetters980]

What is this New non-invasive Procedure called TULSA PRO ???

[@jeffmaihack]

How do DRUG contracts affect a man's treatment options?

[@robbieru]

Thank so much for your videos! I had a prostatectomy back in June. My three month PSA was .18, my doctor order a psma pet scan and a follow up test. the results were a PSA score of .44 and the psam scan showed a lesion (1cm) on my right pelvic bone. After visiting all the referrals, the radiation oncologist suggested 5 sessions of high intensity radiation to the pelvic bone, followed by 34 sessions of low intensity radiation to the pelvic area. My medical oncologist suggested 24 months of ADT with a cocktail of medicines such as: Orgovyx, Zytiga, and Deltasone. Is this the normal protocol? or as mentioned by a friend doctor (Naturopathic) "...this is an overkill..." Any opinions on this suggested treatment are highly appreciated.

[@marketsqueezer]

I am 60 and from Denmark. I have prostate cancer, my PSA is 30, cT3b tumor and my Gleason score is 4+3 = 7 high risk. Monday I am going to have a 2 hours PSMA / PET scan to see if the cancer has spread to more than a small area. The doctors say it is too late to use surgery, because it has spread to my two sperma-bladders that are close to my prostate. I am on a strong Keto-diet, so I am trying to kill the cancer myself. I feel the diet helps. The doctors suggest radiation and hormone therapy. I will refuse hormone therapy.

[@GeraldMarnon-r4f]

Wise move GOOD LUCK❤❤❤

[@southernload5710]

My prostate cancer spread but 40 radiation treatments and 18 months of hormone therapy put me in remission. I'm now cancer free and treatment free. It was tough but worth the long 2 years of hell.

[@marketsqueezer]

@@southernload5710 I am going through 39 radiations, but I am going to avoid hormone therapy, because I believe it will change so much.

[@jsroesler1]

Hi Alex, I have a question for Dr. Scholz! Can you tell me about using a second-generation ADT to radiosensitize metastasis? With a PSMA PET scan, we might find oligometastatic disease and then want to do MDT-metastatic directed therapy with focal ionizing radiation to the metastasis. With mHSPC, is pre-radiation treatment with a second-generation ADT considered a standard of care? Will it likely be covered by insurance? (I saw some published papers from pre-clinical studies using 2nd-gen ADT for PCa as a radio-sensitizer before MDT with focal IR. Could that be done for mHSPC? I have a rising PSA of 0.34 with DT of about 9 months at 7+ years post-RP and 2 1/2 years post-SRT. A very recent PSMA PET scan did not reveal any mets. If and when mets show up, I wonder about advocating for 2nd gen ADT before focal IR as part of MDT. All this scientific literature is a bit overwhelming to understand.) Elsesy, M. E., Oh-Hohenhorst, S. J., Löser, A., Oing, C., Mutiara, S., Köcher, S., ... & Mansour, W. Y. (2020). Second-generation antiandrogen therapy radiosensitizes prostate cancer regardless of castration state through inhibition of DNA double strand break repair. Cancers, 12(9), 2467. Kakouratos, C., Kalamida, D., Lamprou, I., Xanthopoulou, E., Nanos, C., Giatromanolaki, A., & Koukourakis, M. I. (2021). Apalutamide radio-sensitisation of prostate cancer. British Journal of Cancer, 125(10), 1377-1387. Elsesy, M. E. E. M. (2023). DNA damage response and double strand break repair in prostate cancer: From mechanisms to clinical application (Doctoral dissertation, Staats-und Universitätsbibliothek Hamburg Carl von Ossietzky).

[@Sundog1966]

I don’t see the weight program link that was mentioned. Maybe I am missing it?

[@ThePCRI]

Here is the link to a simple weight training protocol to follow: shorturl.at/Da9Bn

[@spare016]

PSA50, Gleason 8, locally advanced, Pet scan no spread, 61 years, did 21 sessions of radiation and now after 18 months of ADT PSA came down to 0.02. Like to stop but doctor insists to continue with another 6 months of ADT because he sees me as high risk. Bur Dr Scholz is mentioning that 18 months is sufficient. I could handle the first 15 months of ADT but it is getting more difficult now, especially for my legs.

[@m4rinos]

@@ThePCRIif you say you’ll put a link down in the description, do you actually mean comment section? I’ve run into this problem a few times.

[@KDean22]

SHUN ADT. ITS A KILLER. MY PSA IS 264, DOWN FROM 1200. O AM 75. I REFUSE ADT UNTIL 2 YEARS FROM RADIATION

[@MrTheherd]

You talk of six months or 18 months of hormone therapy and then the impact is reversed. But my reality, and that of probably at least 30%, of older men is that testosterone does not ever recover to normal levels. So I think any initial discussion with patients should be upfront about the long-term risks (even from allegedly 6 month treatments) and should set out how these effects can be eliminated (eventually) with testosterone replacement - at least for those with intermediate risk PC. So it was a little disappointing not to see this covered, although it has featured in other of your videos

[@Lapohaus]

Get testo booster