McArdle's (Glycogen Storage Disease Type 5) lecture for USMLE

[@TheDreamingIris]

*Mistake A "second wind" phenomenon is an improvement in myalgias, muscle stiffness, initial fatigue, and tachycardia after approximately 10 minutes of exercise (NOT REST). This "second wind" can be explained by increased blood flow, enhanced delivery of free fatty acids with concurrent activation of fatty acid metabolism, and also increased hepatic glucose utilization.

[@mesosil3330]

Thanks for sharing your bright ideas to us

[@thestudyspot]

You are so welcome!

[@clarissegibbons3348]

Great explanation. I have the disease and am using to to explain the disease to my friends. Thanks!

[@rhondacarda8502]

You are wrong. I have this disease and symptoms can occur at the beginning of any exercise. Walking especially with inclines. Even if it’s slow I can still have symptoms.

[@begonyaruya522]

Çok haklısın

[@p.eb0441]

This was really helpful thank youu

[@hanhnguyenhong7561]

Thanks youuuu

[@luiginavandenbril1401]

Can you explain the heredity of this disease? It runs in my family...

[@samuelnyandwi3349]

This video was soooo helpful! Thank you

[@riri23245]

Can anyone explain why no lactate please? i kinda didnt get it .

[@mariamaboutouk8849]

Thank you so much

[@nguyenha-dn6ds]

Some segments in the video are stamped not adjacent to each other

[@usmlecareer180]

genius explanation ever / thank you bro

[@fatemaatia4385]

Great video waiting for the rest of GSDs

[@melodytheodore2954]

fantastic video thanks

[@gandibachi87]

great vid.

[@PedroHenrique-nw2vi]

the video image is too poor, you need to fix it more

[@MimmiEkman-h2i]

exercise INtolerance* :)

[@clarissegibbons3348]

M activity* intolerance... i have the disease, and I experience fatigue with in seconds to minutes of walking or any other physical activity.

[@robertolinaresduran9477]

why ammonia is high excuse me

[@User1_2_3_4]

High ammonia is Natural by product of exercise therefore expect it to be high if you exercised enough

[@survivorph4744]

I dont understand medicine but i have condition cough it allmost one year already .sorry for my wroonh grammar

[@ianmacdougall2467]

Too many errors

[@majkelbenchecustodio5795]

You really need to chill while you're discussing this

[@thestudyspot]

+Majkel Benche Custodio By chill, you mean slow down? I have heard that critique a lot. I will remember that in my future videos. In the mean time You can watch it on slower mode.

[@majkelbenchecustodio5795]

ok. that's why we have drugs

[@medicineislifeee]

Lol, I think you're fine. I used to watch it on 1.5!

[@PaulOBrienChina]

i watch it on 2

[@TheHiggsbosom]

Go at your natural pace, we can handle the playback! Great videos!