Von Gierke (Glycogen Storage Disease 1) for USMLE

[@hraqhraq]

Finally someone understanding pathophysiology and molecular pathology of the disease they are talking about it. Very useful. I can add that PPP is anabolic first then catabolic at the end, not just catabolic as you said, because there would be more purines synthesized and when cell senses that it will pass it to XO enzyme for catabolism

[@shantanubaghel2058]

Just wanted to say this video saved me for Step 1. Had a classic von Gierke but couldn't remember details. Thought of your pathophys breakdown and boom, got it. Thank you. Keep up the great work.

[@ashimadogra4523]

omg same! After watching this, I didn't have to even read the clinical manifestations from kaplan etc. It all came to me logically!

[@DocRen]

Only 2 minutes in and this makes so much more sense already. DANG THANKS

[@duaajaffar1263]

That was truly helpful thank you so much ❤️ Please keep posting more

[@afsa2973]

Thanks a lot. You made it super easy to understand ❤️

[@leahodonnell9967]

Great video! Super helpful in my biochem studies, thanks!

[@reemnb1409]

manyy thanks IT WAS SUPER USEFUL

[@zoezzz8934]

thank you!!! so clear and helpful

[@ananyabasak8231]

Thanks sir it's very helpful to understand.

[@osamabinkhalid4100]

You are great

[@aoi7910]

Very well explained! Amazing presentation, hope you're doing well :)

[@thestudyspot]

Thank you! You too!

[@norma9237]

Thank you so much

So glycogen builds up or no? or just the glucosa 6 phosphate?

[@felice98]

Amazing Video! I have a question: Is the synthesis of TAGs by the liver in the fasting state for the purpose of supplying energy to the rest of the body or are they rather stored?

[@jasmineouiarmaldz1935]

A huge thank u mister 👍

[@livebiochemistry]

great video

[@ranonepal6851]

wonderful..thank you very very much sir...

[@mariaalarcon7711]

Thanks for the vid! It help me a lot

[@amfarawi]

great video. 10/10.

[@sk5869]

Damn this is so good!

[@thestudyspot]

Thanks!

[@naveenkumar-sz1cg]

SO MUCH HELPFUL THNQ .

[@rafaelgalvan4066]

Why the G6P has to be inside the ER?

[@SuperCoccyx]

Thanks.It helped a lot.

[@thestudyspot]

Eugeniu Lupusor Your Welcome.

[@ruqayasuadad3105]

thanks♥ great work

[@thestudyspot]

ruqaya suadad Your Welcome!

[@star2653]

Hi sorry this could be a stupid question but, how is there a decrease in glucose 6 phosphate? Surely there would be an increase of it because it cannot converts into glucose? You were talking about this at 8:30

[@tonyberardi1617]

He meant gluocose-6-phosphatase. It's easy to confuse so many similar sounding words lol

[@priscilla_7733]

Is it normal to develop a lot of food allergies as u get older? If so, why?

[@محمدالعنزي-س6ث7ث]

thank you ♥

[@thestudyspot]

+‫محمد العنزي‬‎ Your Welcome

[@katesn9052]

Thanks a lot! I love you