Trinucleotide Repeats

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[@DirtyMedicine]

*Myotonic* Dystrophy is spelled incorrectly on one of my slides. Apologies.

[@tarunendudwivedi8872]

Which is the best question bank to study for Psychiatry Board exam?

[@drasmakhan9619]

Hey.. is it macro orchidism or micro in fedriech??

[@abbey3354]

@@drasmakhan9619 macro in fragile X, micro in Klienfelter syndrome

[@spencerhemmerich193]

For the Friedreich's Ataxia mnemonic, you can also remember iron accumulation by emphasizing Fe in "Lady GAA-GAA Fell" :)

[@goahead3654]

ohhh my gooooddddd!!!! just in timeeee!!! I was just about to read this and here it appears!! this is just wonderful! thank u so much!!!

[@mehinmammedova6452]

I wish I know this channel way before that’s really really helpfull and you’re the only channel that I can focus and finish it, generally videos are really short and compact and really really explanatory 👍🏻👍🏻👍🏻👍🏻👍🏻 Thank you 😊

[@hopskip1746]

Thank you for making these videos and making them so accessible

[@Rain-on3ek]

the mnemonics really do a wonderful job at helping me remember! Thank you so so much😄

[@rahmakamil1993]

I keep checking your channel every single day waiting for a new video ,, thanks a lot

[@aunshawilliamson6847]

For Huntington's, the CAG also describes what you mentioned was decreased: Caudate, Acetylcholine, GABA. Thanks!

[@youssefhamdy6008]

and it can also remind us of symptoms like C-horea and A-ggression

[@getbuffer]

I got a question in my exam about the CTG, followed by association symptom question “Cataract”. Thank you so much for your mnemonic. Easy 2 points ❤️

[@ahmadqubo]

You man are the best! your channel is the only channel that I turned on the bell notification alarm for. Thanks a lot

[@pinoy7tfc]

heres another one for Huntington that came super useful in basic sciences for me: CAG = Caudate Atrophy GABA

[@pinoy7tfc]

oh and heres another one that my friend made for Fragile X they got big balls so they Can Get Girls

[@katerynat.9144]

This is really helpful, thank you!

[@Be1smaht]

Gold

[@dr.humayoungrewal6362]

This man means business.....astonishing, fabulous I was trying to memorize this but I use to forget after multiple attempts...you made this crap ridiculously easy man

[@drswetaruparel]

Your videos have been really helpful !!! 👍 There are some changes in exam pattern from 4th May, 2020. Apart from increasing questions to test communication skills, they have removed patient care part from 'competency' section. It is really confusing. It will be really helpful if you make a video regarding changes and advantages/disadvantages due to changes. Thanking you in anticipation! 🙏

[@1412Z]

Thanks! May God bless you.

[@ileanamendez7339]

You’re incredible Dirty thank you!!

[@DRABENIDRLIDU-eh9yx]

Your work is smart as usual.

[@10bears60]

Thank you very much!

[@DrRomaMD]

FriedArcH Gaa-it Arc for foot deformity like and arc arch of foot H for hypertrophic heart Small 'aa' for Autosomal recessive trait Gaait in all ataxic gait ❤️

[@nanaz8473]

Bless your beautiful kind soul, every time I see you have a video on a topic we are taking, my heart feels happy

[@xaaboopinkly]

You’re the best, thank you soooooo much!

[@hughvis]

Whoever you are, Dirty Medicine, You are an absolute rockstar.

[@starlight200816]

been using your stuff all dedicated couldn't believe I didn't hit subscribe already but thats probably I was just mesmerized by this channel

[@dilkushathanzeel4662]

Thank you so much

[@ErosGontijo]

Now that's awesome!

[@monzilachowdhury6590]

Incredible !!!!!

[@asantefarquharson2416]

Thank you so much! This is amazing

[@drwakenyanabiswa9789]

Great stuff

[@dingdong436.]

Wow. Great mnemonics! Went straight in to my head🤩

[@hiud11]

LMAOO I immediately went to find the 2018 lady gaga & fan fall and now i will never forget friedreich's ataxia! Thank you!

[@BaconLover1218]

Huntington's has low CAG (Caudate, ACh, GABA). Friedrich's ataxia = GAAit, HCM Fe fate.

[@suriosha]

Loved it

[@mogtaba3idroos450]

it is great job thank you

[@muhammadjunaidali769]

Awesome

[@yashpawate1306]

wow! just in time for my biochemistry NBME-- thank you so much. Please upload some biochem too!

[@zahor0269]

Haha, Myotonic Dystrophy is really "Handy" its (CTG)n because they cant terminate their grip.... I love it!

[@gohersaeed8107]

THANKS DIRTY

[@CP-ov8sd]

other mnemonic for Huntington's repeat: HUNTers put animals in (CAG)es

[@noornoor-yv8tu]

Thank you so much 😊 that was helpful.

[@danrosenfeld2114]

Solid

[@maxrules2161]

Why is anticipation more common in tri-nucleotide repeat conditions?

[@Bella24Forever]

APCD of Huntington

[@TenaciousP45]

Fred Tax like GAA, we gonna be A*ll R*ight

[@CP-ov8sd]

Fred. Ataxia= GAAit ataxia

[@spideylover4105]

Yoooo dirty give us your hot take on usmle being p/f now

[@DirtyMedicine]

uploaded. check it out

[@imonlyherefordrhighyield]

.........i was literally at that lady gaga show

[@sahmal-mada3989]

nice video, but don't forget to edit the word ( gammaglobulinemia ) in myotonic dystrophy

[@nurlandav6356]

thank you dirty medicine

[@mane6377]

I have a doubt U said x linked dominant would be from affected father to daughter . And x linked recessive is from affected mother to son . Is this case an exception?? Of x linked dominant

[@usmleislife3396]

Hey kindly can u upload video hypothesis error null hypothesis beta and alpha error and confidence interval ,, p value....

[@sitapokhrel8837]

Gammaglobulinemia is also spelled wrong😁

[@drwakenyanabiswa9789]

Hahah 😂

[@viklondon3466]

Dirty is very good.

[@superdragonsunshine]

Bro wtf. How do you make everything so free? It’s kinda dirty.

[@ayshasarmad1240]

Please re upload breast tumors and those nemonic series videos its a request

[@kissmeimhuman]

Important feature of Fragile X not present in this video - " Mitral valve prolapse (MVP) is present in about half of all patients with fragile X syndrome and while it is usually a benign condition, it may lead to mitral regurgitation. In fact, MVP is the most common valvular cause of chronic mitral regurgitation. Patients with fragile X syndrome are also at increased risk of developing focal seizures, which occur in 10-20% of cases. The underlying mutation of the FMR1 gene leads to imbalances of neurotransmission, causing neuronal hyperexcitability. The seizures can be with or without impaired awareness. The majority of cases have a good prognosis and seizures resolve spontaneously during childhood. "