Waldenström Macroglobulinemia | IgM antibody

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[@MedicosisPerfectionalis]

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[@baraaayman3783]

I was so close to fail in hematology chapter until I found you .. So great .

[@MedicosisPerfectionalis]

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[@MedicosisPerfectionalis]

The series of platelets is already available...Click here: goo.gl/Dt41Bg

[@eyaayadi9053]

I wish that I found your channel sooner! I am sitting for my hematology exam in 2 weeks and your channel is so helpful! thank you so much!!

[@MedicosisPerfectionalis]

My pleasure 😇 Good luck 🍀 to you!

[@ELFCloudGamer]

I've been stuck on haem for like one month until I found your videos, so happy!

[@MedicosisPerfectionalis]

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I love how you teach! TY

[@MedicosisPerfectionalis]

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YOU ARE AN AMZING PROFESSORIN MEDICINE. WITH ALL MY RESPECT I SEND YOU MY APPRECIATIONAND I CONGRATULATE YOU FOR YOUR PERFECT EFFORTS.

[@MedicosisPerfectionalis]

Thank you so much 😊

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Soo explicit 😍

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Thanks a lot for your great videos! From a Japanese med student

[@MedicosisPerfectionalis]

I am honored...That’s great that I have students in Japan...Please let me know if you have any questions, any time...Thanks 👋

[@Almedicosis]

wow this is incredible precise and easy to learn！

[@MedicosisPerfectionalis]

Thanks a million, dear!

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[@MedicosisPerfectionalis]

My pleasure 😇

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In my life, there is no greater hero than you

[@MedicosisPerfectionalis]

Thank you 😊

[@saralissali1090]

I love u u make medecin so easy

[@megangardner_science_and_art]

I’m so happy I found your channel 😍 Great work; keep it up please!

[@MedicosisPerfectionalis]

Same here 😃...I sure will! What’s your field of study?

[@megangardner_science_and_art]

Medicosis Perfectionalis I’ve studied Biomedical Science (and work in labs - Haematology and others) and your videos help me to refresh my memory. Your explanations are very clear and your video library extensive. I really appreciate any videos about laboratory tests and medical conditions. I’m definitely looking forward to your future videos. Can I suggest videos about the science behind immunology tests such as ANA, AIP, Anti-CCP etc for autoimmune conditions. Thanks for your work!

[@MedicosisPerfectionalis]

Have you checked my Rheumatology playlist? I have discussed many of these topics already.

[@megangardner_science_and_art]

Ah brilliant !! I didn’t notice those before. I was looking for those types of videos under Immunology previously. Thanks for pointing them out; I’ll go through them :)

[@MedicosisPerfectionalis]

Super! Please let me know if you need any help, also you can send me any questions on Facebook or email if you wish...Best of luck 👏

[@zpto12345]

Excellent videos.. Beautiful graphics... Highly interesting presentations... Had a doubt regarding Coomb's test ... Coombs test is for detecting of incomplete IgG antibodies ( sometimes IgA ) ... In Waldenstrom's macroglubulinemia there is abundance of monoclonal IgM antibodies which are complete type... Why they would require coomb's serum for producing visible agglutination in saline medium ?

[@yasminaoulami2140]

great work thank you so much it's very helpful 🥰🥰🥰

[@MedicosisPerfectionalis]

My pleasure 😇

[@hydrogendioxide483]

I have my hemato exam in a week! Wish me luck as I have studied thoroughly😊 Thank you so much for these videos💜

[@MedicosisPerfectionalis]

Thank you 🙏 How was your exam?

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Can you pleeeeeeease do a series on blood bank and Clinical Chemistry? All the medical Technologists will appreciate it, since its a forgotten profession😰.....we take exams all the time for licensing and you are by far the best in the game

[@MedicosisPerfectionalis]

Thank you 🙏 Can you tell me about some textbooks to study from?

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@@MedicosisPerfectionalis Blood banking and transfusion practice (kathy D. Blaney)

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[@forgivelovelive2760]

Can you help me with the overproduction of antibodies destroying red blood cells Agglutenin- Hot or Cold. What makes the red blood cells burst from the attachment of antibodies? And what makes the body overproduce antibodies?

[@fahadmirre9980]

Very nice friend, i will share the page to thousands m students

[@MedicosisPerfectionalis]

Thank you!

[@user-kp4me5xp1s]

Hi.you are great amazing .keep learn more and more and create .thank you very much

[@MedicosisPerfectionalis]

My pleasure 😇 Thank you ☺️

[@shawnpinn9177]

Awesome thanks

[@MedicosisPerfectionalis]

My pleasure 😇

[@kaunhai4512]

Thanks for the video

[@MedicosisPerfectionalis]

My pleasure 😇

[@JALSKY1]

I was diagnosed with Lymphoplasmacytic Lymphoma and Anemia. Is Lymphoplasmacytic Lymphoma the same thing as Waldenstrom Macroglobulinemia? Thank you for your time.

[@samahahmedmohamed906]

Can you please explain lmmunoglbulin rearrangement

[@sabasagliker5599]

Hi dear @medicosis

[@MedicosisPerfectionalis]

Good question! Let me ask you: what’s the mechanism of action of IVIG?

[@sabasagliker5599]

@@MedicosisPerfectionalis It is used as Ig replacement e.g. secondary immunodeficiencies

[@michaelsingel6369]

@@sabasagliker5599 Good question to ask yourself Is there any IgM in IVIG? Does the excess IgM from WM suppress other antibodies and if it does how does that affect your immune response?

[@roserositta1441]

awsome

[@MedicosisPerfectionalis]

😊

[@srinivasaraosirasapalli5104]

excellent

[@MedicosisPerfectionalis]

Thanks 🙏

[@drme4895]

Thank you by chinese 谢谢🙏 amazing🎉🎉🎉

[@MedicosisPerfectionalis]

Thank you!

[@josephhsheimi9721]

Just rewatched this. Always a good refresher, but I have a quick question. You mentioned that HSM is less likely in IgM MM compared to WM, but you could still get it in IgM MM if you have extra-medullary hematopoiesis due to suppression of the BM, correct?

[@MedicosisPerfectionalis]

By HSM, do you mean hepatosplenomegaly?

[@ameterasu13]

Wait excuse me you said the type of anemia associated with Waldenstrom macroglobunemia is Cold Autoimmune Hemolytic anemia. I get that because of IgM involved making it autoimmune but what about when you mentioned now Normocytic normochromic anemia I don't get that sir I am little bit confused now 😭😭😭.Please explain to me now what is the difference or similarity by the way your videos are much nicer than lecturio or osmosis

[@cherrrriii]

heres a little mnemonic: Waldenstrom flip the W you get M which is the type of antibody xD

[@ingarizova4060]

Hallo! Thank you for the videos - they are really helpful! In the "Lab"-Slide you mention the serum viscosity as one of the Lab test. I am from Germany and I work in the Lab and I have hardly heard of this test before, it´s not used here for the the diagnosis or monitoring the WM. Is this Test a routine practise in USA and with what method ist it performed? Is it used for diagnosis or only for monitoring? What about the quantitative IgM measurement in serum?

[@MedicosisPerfectionalis]

It’s not a must! Other tests are more specific.

[@opinionminion4189]

i didnt understand the difference between the esr causes in the end but thanks for everything else

[@MedicosisPerfectionalis]

You’re welcome 😊 So, what didn’t you understand about ESR?

[@opinionminion4189]

@@MedicosisPerfectionalis I didn't really get the difference between the two reasons for high ecr

[@hammhann3818]

Thank youuu sooo much 🌹 And please what's the meaning of ESR ?! 😅😇

[@MedicosisPerfectionalis]

Erythrocyte Sedimentation Rate

[@thoughts_in_mind]

Writing hematology tomorrow and I'm only starting the series 😅😭

[@MedicosisPerfectionalis]

I wish you success!

[@dichan4928]

Is it hereditary?

[@naluh_n]

Baby it's cold inside😙

[@jenq436]

My father died of that.

[@FadyAbdulsattar]

what the flip 🤣🤣🤣

[@MedicosisPerfectionalis]

:)

[@aya_Bou]

can't thank you enouuugh ....

[@MedicosisPerfectionalis]

My pleasure 😇