Sodium Potassium Pump

[@Mister_MasterzRN]

It’s amazing how much more I absorb watching these videos. Speaking for myself personally, i’m dyslexic and also have ADHD and I’ve tried various methods of learning. These animations has been by far better than any outline/PowerPoint I’ve ever been given. Watching this helps with getting the information to stick! Thank you so much for these videos keep them coming!

[@rayalmeida1356]

Amen!!! (My last Bio prof used these to Supplement her stuff. So, combining both works).

[@carndela7032]

My bio teacher is dyslexic, kool

[@No_auto_murk7220]

wurt @@carndela7032

[@user-op2zc6hj5d]

Y’all this got me through class

[@adnin8968]

hi , do u knowwhich chapter this is from?

[@pedromiranda7346]

@@adnin8968 Chapter 2 for me, but referenced again in Chapter 11. Biochemistry and the Nervous system.

[@Chr1st1na1]

Can we all take a moment to appreciate the effort and mostly the humor these girls have put in the video? Thank you so much amoeba sisters you are amazing at explaining so easily and understandably difficult biology mechanisms !! I would love to see a video about Krebb's cycle!!♥

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I was just going to request a Kreb's cycle video!! These videos are wonderful.

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I'm not even biology student but these videos are so engaging that I end up watching many of them for no apparent reason.

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These people deserve an award for helping people learn chemistry in an adorable way!

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The machines working inside our cells are so amazing. We are so incredibly well engineered :) I'm just an old guy who enjoys learning. Keep doing what you do :)

[@agreatdain63]

Watched these videos in highschool and they have me coming back in college! So unbelievably helpful in a pinch for exams and it's a major plus that the art is adorable and simple.

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Only legends came here from their bio class

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Only legends watch this at their free will

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Me casually sitting in Bio class

[@lorenzowildam7066]

Same😂

[@mathiasschilling]

​@@lorenzowildam7066 U casually sitting next to me

[@dog-jk2hn]

Just replying to this so you can cringe at it 3 years later.

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First, I’m a fan of ur channel my teacher shows us your videos every time

[@elan344]

same

[@ebonyriley476]

If only you guys did chemistry... but you guys helped me out a lot last yr😭

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Amoeba Sisters your channel is one of a kind. Last unit test is just next week and finals the following week. Going through your vids for a good review😊😊

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I used to watch these videos through my school years, and here I am in uni coming back to them because ur illustrations help me understand better, thank you for working on these master pieces!!

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Im almost 35 but I watch your videos because it's very descriptive and realistically explained.

[@alcira4282]

Never really commented on your vids but I love them! The commentary is great quality and so is the animation!

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As a teacher I always use your videos for my lessons, I’m considering signing up to be a patron too because I really love your work!! I would love to see a video on Photosynthesis (light dependant/ independent reactions) and respiration (glycolysis, Krebb Cycle etc..) as these are topics students always struggle on.. THANK YOU @AmoebaSisters ❤️❤️

[@blast8012]

Hello teacher, I have a question Why use the carrier protein instead of the channel protein? The potassium can exit out of the cell through the channel protein right? So why not use the channel protein?

[@muhammadyusufalfarisi9196]

@@blast8012 In my opinion, because channel protein cant take the potassium back to the outside of the cell (extracellular cell). Channel protein only provide molecules from outside to the inside cell (intacellular cell). Carrier protein provide the molecules to in and out of the cell

[@blast8012]

@@muhammadyusufalfarisi9196 Thanks for replying I think i understand a little better now Btw are u from Malaysia Just asking

[@muhammadyusufalfarisi9196]

@@blast8012 glad u understand, im indonesian

[@blast8012]

@@muhammadyusufalfarisi9196 Oh ok cool

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I hope it goes well for you, my love! ❤️

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This channel is so underrated compared to the other educational channels

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The amoeba sisters are AMAZING!!!!!! I cant believe that Im just discovering your channel. Everything I nee to know is explained and some how it all sticks in my brain. God bless you ladies! Please don't stop making videos.

[@rivitraven]

This really helped me understand why having proper amounts of sodium and potassium in my diet is so important.

[@LordButler]

Since this video is old I won’t expect a response, just want you to know y’all are AWESOME!!!! I’m taking A&P 1 and in two different sections the sodium potassium pump was explained and it made ZERO sense to me. So, I thought I’d look on KZbin for something more helpful. I clicked on your video after seeing the animation (simply because I wanted to see how silly it was) and to my absolute delight, not only was it very entertaining but …it finally made sense to me!!! THANK YOU, THANK YOU, THANK YOU!!!

[@sadmimashahrin6769]

Ok i never knew a complex thing could be made so fun and cute! Absolutely loved it...

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Thank you for putting so much effort into helping us!

[@AmoebaSisters]

Thank you so much for the superthanks!!

[@-RocketAnimations-]

Thank you! I am the number one sodium potassium fan!!!!!!💯💯💯💯

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All I can say is thank you so much! You are doing a great job for all of us struggling out here

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Thank you for making Biology fun. You're simply amazing.

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Im at a school were the core subject is biotechnology and I loveeee your videos, they make my studying sessions so much easier. The best part of it all is the humor. Please keep doing what you’re doing

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You have no idea how useful this is to me! Thank youu, your videos help me to understand the concepts that takes hours if I were studying em using the text books. God bless you both. Love from sri lanka❤🇱🇰

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Holy heroes, a moment for these sisters for their incredible work 👏... my only hope for my A+P I exam tomorrow 😅thanks amoeba sisters... YOU ROCK!!!

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My teacher shows your videos almost every class it’s very helpful!!! Thanks for making a difference!

[@derekdeadlifts2986]

This got me through my chemistry class last summer in college. For that we thank you.

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You guys help so much with my anatomy and physiology class you dont even understand! Thanks for all the hard work you guys put into the videos!

[@mic4600]

Your videos have been so, so helpful through quarantine online classes. I can't thank you enough!

[@onlystudy7975]

I love this simple way of explanation I also love the cute graphics, they make me smile I wish I could get my education in university as simple as that I wonder why your platform is not created yetPlease, I want full explanations of medicine You're videos made me love to study You're the best Thank you amoeba sisters💕💕

[@JK-vf2hp]

I've watched many videos on this pump and your video made everything click. Thank you!

[@linus2812]

Your videos are really helpful. I‘m from Germany and my biology (bilingual subject) teacher showed us this years ago. I still use your videos to learn and i graduate this month ☺️

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I love this channel so much. It's such a great source for clear concise and digestible information!

[@riyabotadra7170]

It’s 2 am and let me tell you, there hasn’t been a better video for me than this as a bio student. Y’all saved me from a potential panic attack cause I knew nothing about this 😭

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It's always a good day when the Amoeba Sisters upload

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OMG !! Just this morning I was wondering why the Amoeba Sisters don't upload anything nowadays....... And here it is.

[@dauts]

i never would make it through school without this! thank you so much!

[@yasminsahagun5401]

WOW, what an amazing visual for such a complicated subject!! This helped a ton for my physio class!

[@pigeonproductions848]

Like if you know what the Mitochondria does!

[@alexanderpapazov5441]

The mitochondrion is the site of cellular respiration, a process which takes stored energy (glucose) and turns it into useable cell-energy (adenosine triphosphate).

[@littlefred907]

Mitochondria is the powerhouse of the cell

[@profmonkey0756]

Mitochondria or midichlorians?

[@vanitoes]

Powerhouse of the cell

[@rebekahgriffith4292]

@@profmonkey0756 LOL IKR Love it

[@sallymoran2257]

Hey Amoeba Sisters! Thank you for fulfilling my curiosity and eager to dig deeper into biology! You guys are amazing!

[@Random13Guy]

Thank you for this explanation! Had no idea about this pump stuff and now I'm leaving with a bunch of clear cut concepts.

[@B-ek8xk]

I have a physiology exam and I finally understood this topic. Thank you for this beautiful explanation🫶❤️‍🩹

[@suryadeepkumbhakar6346]

By watching this videos the theory in books become very much clear, thanks

[@jakiyahr2689]

I made a 100% on my first bio test with your videos.

[@sugarcoder]

This video is so useful! I just learned this in class, and it is confusing. Thank you for this video, because it made things a lot clear!

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The Amoeba Sister are changing my life!!

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Thank you for making everything so easy to digest! Watching this right now as a freshman nursing student! 🫶✨

[@furangel]

a 7-minute video it turns into a 10-minute ordeal because I have to pause and rewind because I start giggling too much at the cute cartoons and I lose track :D Thank you for these videos! I'm currently in nursing school and having to refresh some basic concepts and these videos are so helpful! Why can't everything be explained with cute cartoons?!?!

[@ajf7268]

You just reminded me of Finding Nemo and Finding Dory Pinky, I like how you bring the best through Science, Keep up the good work!

[@aisham3312]

Love it. This topic is the reason why if to from my AMP class. But this video seems very comprehensive. I know I probably will have to re- watch it for like 20 times untill I get it.

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Im in 6th grade and I like to watch this videos for fun and because they will help me in the years and also because they are funny.

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You're minute physics for biology. Keep it up

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u do not realise how helpful this channel is! please never stop! also would love it if u guys could explain physics too!

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My science teacher loves your channel

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I've tried learning this process through another video but yours always make things simple and enjoyable to learn, thank you for all that you do!

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amazing how easy to understand these videos are

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Good luck on your test!!! \ (◕ヮ◕) /

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I love theses video so much. Thank you for continuing to make them. They help me so much.

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I absolutely love your videos I use them to study for my exams

[@Celti_]

1:20 The sodium potassium pump requires an input of energy from Adenosine Triphosphate (ATP). One major function is to help maintain a resting membrane potential between Na+ and K+, two ions with positive charges that have trouble traveling directly through the plasma membrane. As a result, they require a protein to travel through (either a channel or a pump), in this case, the sodium potassium pump. 1:54 Resting membrane potential involves the cell's electric potential. EP is the difference between the electrical voltage inside and outside of the cell. Cells have their own resting potential depending on the type of cell. Generally, most cells are more negative inside the cell than outside. 2:15 For many cell types, when this resting potential is changed by some type of stimulus, there's a response. Muscle and neuron cells are excitable cells and many of their functions depend on a change to their electric potential - explore action potential for more details. For a cell at rest or if it needs to return to its resting potential, the Na+ K+ pump is very critical. 2:51 The Na+ K+ pump is initially open on the intracellular side of the cell, it has binding room for THREE Na+ ions. When these three sodium ions bind, the protein is PHOSPHORYLATED (ATP transfers one of its three phosphate molecules to the protein and changes the protein's configuration/shape. The shape change causes the pump to open to the outside (extracellular side) where the three Na+ ions leave and TWO K+ ions bind. The protein reverts back to its original shape within the intracellular side of the cell. The two K+ ions are released within the cell. Now there's room for three sodium ions and the cycle repeats. *THIS PROCESS MOVES SODIUM AND POTASSIUM AGAINST THEIR CONCENTRATION GRADIENTS*. With this active transport, the ions are moving from LOW concentration to HIGH concentration since there's already more sodium OUTSIDE of the cell and more potassium INSIDE of the cell. 4:45 Voltage difference in the resting potential is caused by more potassium ions inside the cell and more sodium ions outside of the cell resulting in an electrochemical gradient. This means there's not only a difference in charge but also in the actual ion types. 5:27 Many cells have far more potassium leakage channels than sodium leakage channels. This makes the cell membrane more permeable to potassium at rest. Positive potassium ions that travel OUT of the cell contribute to a more negative charge INSIDE the cell. 6:02 There are other ions that can contribute to the resting potential as well. 6:17 There are other proteins that rely on the electrochemical gradient to move critical molecules. Proteins that move in glucose are an example.

[@salvatorenapolitano8734]

You are better than my actual biology teacher

[@LeekStick]

Currently watching in my Anatomy and Physiology class

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I come here to review after listening to lectures, then go to school & actually understand the material

[@tanyamartinez8174]

Thank you! I needed this for muscle contraction in A&P. I forgot alot of the stuff I learned in biology😭