Antiviral Pharmacology

[@Lucky-ff9pd]

The voices of med school I've become very attached to: Dr. Sattar, Dr. Ryan, Sketchy Micro guy, and Dirty USMLE

[@fereshtahkhoshbakht1999]

Me too

[@dailyusmle8710]

@@fereshtahkhoshbakht1999 Whos Dr. Ryan?

[@janicedsouza3087]

@@dailyusmle8710 He's the one who makes "Boards and beyond" videos

[@duhaarafique1271]

Same!

[@gloriac9994]

Dude same lol. I get so much comfort when I hear dirty talking, like its all gonna be okay

[@alitantawy2222]

one way to remember the hep c drugs : -If it ends with "previr" like "previous" so think NS3/4A , also starts with p as in protease . -" ASVIR " like after and starts with an A so think "NS5A" -"BUVIR" starts with b so think "NS5B"

[@redache467]

-previr = protease -buvir = 5B RNA bolymerase -asvir = 5A

[@mohammadadnan6374]

Make sense

[@professorkhan5315]

Really great video!! I wanna add that a major differentiating factor between Foscarnet and Cidofovir is that Foscarnet has a seizure risk (I just think of S for seizure)

[@محمدتقينبيلظاهرحميدي]

As usual, Great video One note , i think that viral thymidine kinase adds only one phosphate to some of the anti-herpetic drugs ( acyclovir , valacyclovir and famciclovir as I remember) and the other 2 phosphate groups are added by cellular kinases, not the viral one

[@obadadaher4851]

give CIDofovir with probeneCID

[@Umir445566]

Thank you so much dude You are a legend. Any chance we can get a signaling mechanisms videos for hormones?

[@akinolarukayat6475]

Have had trouble remembering and understanding these drugs. You made it easier to assimilate. Thank you

[@latifullah8574]

You made it so easy and I am waiting eagerly for HIV anti vitals. Thanks for helping us

[@saintsam7397]

THANKYOU FOR NEVER ADDING MUSIC TO YOUR GOLDEN VIDEOS.

[@IG-qv6sh]

I'm waiting for part 2 of it. This was the most helpful thing in my learning antivirals

[@pallavighatnekar1653]

For cidofavir you can remember given IV saline as I V is in the name cidofa VI r. Thanks so much for your information Dirty Medicine.

[@brookeanderson2631]

Love the way you come up with tips and tricks to remember names and mechanism of action. Thanks!

[@luckymaisha]

Can you possibly do one on antibiotics/microbials? Love your videos by the way!!! Thanks so much for making them

[@abiraafzal7171]

Please do a video on antibiotics!!

[@hi-this-is-stephen]

8:23 - I think it is because of the purine ring structures in the drugs (Acyclovir, Valcyclovir and Famcyclovir). Anyway, your channel help me a lot during my preparation for MRCP part 1 and part 2 written exams. I really appreciate it. Thank you.

[@SG-gw5xo]

Thank you so much for the video, you deserve 1 million subscribers!!!

[@christopherpatrick6949]

Dirty, the absolute worst topic to learn is pediatric developmental milestones. If you could make a video for that I would be eternally grateful.

[@sayedaali6730]

Christopher Patrick he already did

[@christopherpatrick6949]

@@sayedaali6730 Are you sure? Do you have a link to the video?

[@AnilKumar-lo5rn]

i watchd ur videos ovarion tumours very excellent sir....nice pneumonice.....its very help a lot for me

[@xaaboopinkly]

I really don’t know how to thank you!!!!!!

[@emerecene]

Can you do one about NSAIIs and Antibiotics? And I wonder why you didn't mention other Hepatitis types?

[@wacomundo9599]

Dude, thanks so much! I’ve had to give avyclovir a handful of times in the ED and i never new the actual mechanism behind it.

[@serellamadole]

Great video! You made the material so easy to digest.

[@monirafarah4391]

Is this for step 2 only? I heard him say step 2 and I’m studying for step 1?

[@kenibe3507]

You need to know this for step 1.

[@enginoengin1174]

Part 2 pretty please 🤓🤓

[@tijinmathew6478]

In hepatis C NS5B inhibitor which is a RNA -DEPENDENT RNA polymerase is supposed to block step n0 .3 right?

[@mahnoor7726]

Love all of your videos 👌👌👌👌

[@yashpawate1306]

This is just in time for my Microbiology shelf exam. Thank you so much! Please upload the HIV drugs too before saturday!

[@Lucky-ff9pd]

Cellular enzymes add the 2nd and 3rd phosphate

[@xxamulyaxx]

thanks mate... simple slides... love from INDIA.

[@raulblancoazcuy8308]

I loved your video. Thanks

[@drhoneybee973]

Dirty med you are great👍👍..thank you for making things easy-peesy..by any chance we could get a vid on anti-microbials!!!

[@The_Great_Lopaka]

I can't find the JOIN button anywhere.

[@bhatwasim2831]

Love from Kashmir

[@crimzonart1269]

Please upload video on floppy infant Regards Dr. Gawher

[@ambersani6889]

Thank you, Sir... plz upload part 2 as well

[@marine3144]

You just taught me better than my prof

[@eduardotakashitakehara5506]

amazing, as always!

[@kenmiguel2986]

Please do an HiV antiviral video

[@awesomepabla7061]

God bless you

[@pramodthapa2517]

desperately waiting Viral Hepatitis doc

[@elsatkkful]

Hey Dirty! Thank you for your videos, I know you're working hard to bring us these videos. Could you please make a video on the high yield microbiology. Thank you

[@DirtyMedicine]

It’s a huge topic of that I would need to break into several smaller videos

[@rosioorose]

@@DirtyMedicine pls make more and more pharma and immuno videos pleaseeee !you the besttt....pls open a blog too like medicoawesome

[@christopherpatrick6949]

This is what sketchy is for

[@Greanestbean]

Awesome

[@raghadraghad7976]

so helpful ! thanks a lot

[@junaidmushtaq9421]

Thank you so much.. This is high yield for board examinations and u made is easy for us.😍

[@vinodalbuquerque2488]

Sir plz explain on Lamuvidine HBV antivirals inhibitors.

[@PowderChaser]

Another beautiful video!

[@mohamedmetwalli3064]

awesome

[@4agus]

Great video, so useful! you made it really easy. Thanks Dirty

[@cayladoo_1]

u r amazing

[@marianacostaR]

Very good!! As usual

[@nurulaliahrizal]

You're an incredible teacher! Btw please do anti-HIV video.

[@Muuip]

Great summary! Very helpful! 👍

[@drswetaruparel]

Very helpful !!! Thanks 👍

[@majidbashir7102]

Hi sir. Isn't part 2 yet available,??? Part 2 of this video Non HIV drugs ??

[@alih6953]

Great video mate amazing job! I think there is mis-spelling. It is Simeprevir

[@missionvision99]

3:39 6:14 8:11 10:15 11:12 12:29 17:27 18:40 fo SSS carnet

[@PtolemyXVII]

Very interesting! However 1) the antivirals in the AMI group would also block exosomes- due to exosomes uptake of sialic acid, and therefore also affect exosomes' action on T-cells by inhibiting them. Wouldn't this be hugely problematic and compromise the immune system? 2) the antivirals in the cyclone group, wouldn't it also inhibit RNA polymerase in cardiac cells as well as other normal cells due to its inhibition of thyamine kinase? This would mean that normal cells wouldn't be able to replicate. Thoughts?

[@Ifeany1]

the drugs are activate by the virus....the first phosphylation step, making it more specific to cells infected by the virus.

[@usmleislife3396]

Hey can u make video on biostat hypothesis alpha and beta errors confidence interval... it will be very helpful

[@otto9875]

Search on here USMLE biostatistics. There’s a guy i think his names Dr. randy something who Dirty endorsed for his bio stats review. It’s good

[@abdulmohsenalmutairi7102]

Thx 🙏

[@Ruqaya_pearl]

I dont know why im here, i have a surgery exam!

[@junaidmushtaq9421]

😂did you pass

[@Ruqaya_pearl]

@@junaidmushtaq9421 yup

[@ddfelder2]

Thank you!

[@yasinozkul6590]

l-e-d-i-p-A-svir (5A) s-o-f-o-s-B-uvir (5B)

[@ramzarukia120]

love it

[@mohammadadnan6374]

U need to make your own course like pathoma or b@b

[@alhasanmd7305]

Pharmacology profs disliked this video

[@MedManiac1]

legend!🔥🔥

[@lgchinadragon]

thymidine kinase, not thymididine kinase, which you keep on saying. I get this too with phenylalanine lol

[@lichh64]

I love u.

[@crunchycrumbs1049]

turned o n by his voice. am i tripping?

[@crunchycrumbs1049]

sorry, period hormones

[@maryalex9316]

I just wanna express my gratitude to Dr.Ono on KZbin for curing my HSV 1&2. God will bless you Dr Ono

[@coverton]

Sofo5Buvir

[@bobbyboygaming2157]

your video would be half as long and easier to watch if you didnt wast so much time saying "this is like so high yield" like every 5 seconds

[@younaskhan7343]

For best pharmacology classes follow Dr Malik Nouman official