You are quite literally the greatest educator that has ever graced the planet earth. You have a PhD+ level of understanding of every topic you cover, yet you know how to communicate it succinctly and simply. You were born to teach.
@desleykakoulidisgallaway3382 Жыл бұрын
I agree he’s incredible - a genius for sure... not taking anything away - however, Jesus is the greatest teacher On earth ever in fact he is still teaching people worldwide how to live with purpose 🙏🏻
@lik_doyaya Жыл бұрын
@@desleykakoulidisgallaway3382 yeah, but Jesus didn't teach me anything about alpha-1 antagonists in the Bible
@saurabhtripathi966511 ай бұрын
😊😊
@jaygala94206 ай бұрын
It was due to your teaching I passed my 1st Year MBBS with 75% and got 2nd Rank in my College. All set to ace 2nd Year with your lectures Dr. Zach. You deserve all the respect and love from all the students all over the world. A big THANK YOU to you!!!!!
@perpetualifemazi6287 Жыл бұрын
Just a lil correction, the adrenal medulla produces or pumps out 80% epinephrine and 20% Norepinephrine (4:1 ratio) Thank you for your beautiful work😍
@angusmack.2202 Жыл бұрын
I love how no matter what level of understanding you are at, you can always keep up with the video and clear your concepts. Thanks u Soo much!!!
@tarunb6914 Жыл бұрын
at 29:13, shouldnt it be urine retention instead of urinary incontinence?
@inazfaisal5051 Жыл бұрын
Your videos are literally among the best in the medical field! You made pharma so much easier to understand!
@blackfoxmp5 Жыл бұрын
Great lecture overall, but one mistake at 9:48: the adrenal gland secretes epinephrine and norepinephrine at a 4:1 ratio. Thus, 80% of secretion is epinephrine and 20% secretion is from norepinephrine.
@teamdiver8911 Жыл бұрын
you're my lifesaver. I could not get through my nursing career without you.
@pachino11839 Жыл бұрын
An interesting fact about beta blockers is that they can be used as a doping agent on healthy elite sportsmen. During training beta blockers maintain a reasonable cardiac output and muscle perfusion increasing performance as a conditioning agent. During training under normal conditions an increased cardiac output will increase blood pressure only to a threshold where the ventricles need enough time to fill their chambers with blood. If the heart rates increases beyond the threshold the ventricles will fail to pump the 125 ml per contraction. This will reduce tissue perfusion due to a lower mean BP. The beta blockers can keep the heart rate below the threshold effectively during training. This is why beta blockers are banned in competitive sports and considered a doping agent by the IOC.
@mariakara484811 ай бұрын
I am guilty in being addicted to ur lectures ,no words can describe how much I am grateful for ur hard work and fab lectures😘
@GregariousGalaxy20 күн бұрын
The bestest way of understanding. Sir please make videos on microbiology too
@jyothiuddandravu3835 Жыл бұрын
There is no words to say who u are how u are and what you are u r demigod u ur patience your hardwork and your teaching style words cannot describe how I felt like u know everything every topic we r blissed to have u tq so much 🙂👍🤗
@Nikosmentis Жыл бұрын
Best pharmacology lectures on KZbin
@KathleenSethFarillon4 ай бұрын
You'll be the reason why I'll pass my pharmacology subject. THANK YOU SO MUCH
@manalemad1589 Жыл бұрын
u deserve all the best I hope this channel hits the 10 million subscribes , lots of effort and time spent while constructing it every time I meet my other medical student friends I tell them about this channel so I can help growing up this amazing work ,I hope I could help in more THANKS ALOT ❤❤❤
@citytrak Жыл бұрын
Zach - when you are talking about Alpha1 antagonist drugs on the bladder with BPH (e.g. the -osins), don't you mean the indication is urinary RETENTION (2ndary to BPH) not incontenance? I though the idea was with BPH, we get relaxation by the A1 Antagonists, allowing relaxation at the prostate and internal sphincter, which allows for easier urination...
@davideserboni8 ай бұрын
you're right
@saidafirouzi34173 ай бұрын
You are the savior of me and many students out there!
@muslimgirl6179Күн бұрын
Thank you, sir, ❤❤❤ you are the best teacher❤❤❤
@hpinheiroa8 ай бұрын
I already was passionate by phisiology and pharmacology - but u guys u made me head over heels about it. Congrats in everything you do. Helped me see things in such a easier way - even though really detailed
@ubongenoch8841 Жыл бұрын
I thank you sir for your spectacular and remarkable lecture I must confess u are a legend
@ghandigharaibeh93232 ай бұрын
I discovered Zach's only weakness ( he spells the most famous Beta Blocker as Propanolol) ... he does not pronounce it as PropRAnolo) or even spell it. The imperfection that proves his legend.
@lamaaldarwish5095 Жыл бұрын
Thank you so much without you I would fail every pharmacy exam I've ever had❤️❤️❤️😭😭😭
@lissaizzy4927 Жыл бұрын
I always find your videos interesting and I like how you describe things keep up the good work
@cristinajaramillo37786 ай бұрын
I have no words to express my gratitude to you! You are amazing!!!
@tobaccocancer26358 ай бұрын
My understanding level after watching your videos 📈
@videosapienАй бұрын
Sir, The Great Prof, Zach Murphy ❤
@riomacapanas2196 Жыл бұрын
Thank you so much Dr. Zach for your very informative videos,bcoz of your channel I passed the Veterinary Licensure Exam just now🥰u were such a great help to my basic understanding of physiology and pharmacology😊. I will surely share your channel with the future examinees of VLE.THANKS AGAIN AND GOD BLESS😇😇
@saidafirouzi34173 ай бұрын
I cannot express my gratitude and admiration, you are amazing!
@SitaraDreams Жыл бұрын
Thank you all as always for all of your great work and effort. I have a question, wouldn't alpha blockers be treating urinary retention/obstruction in case of BPH and not incontinence ?.
@rajavignesh6749 Жыл бұрын
Yes ..same doubt ,it should treat urine retention
@fusionhypnotic11 ай бұрын
You made this course right when I took pharmacology. You are amazing my friend thank you
@nachi7066 Жыл бұрын
Preparing for prometric exam and very very useful
@shreyagite8225 Жыл бұрын
@29.03 min you said urinary incontinence..it should be urinary retention due to bph?
@j.b.35435 ай бұрын
He made an honest mistake, and you are right, it helps in urinary retention because it relaxes the internal urethral sphincter and thia causes urination
@ahnaf_akif_mbbs_bd_ksa4 ай бұрын
huge airdrop in my medical base May you be rewarded sir 👌🏾🔥
@sajadphbaaaj41023 ай бұрын
Thank you so much. I passed my exam today, depending on you. Thank you, professor
@Cottntale321 Жыл бұрын
A "lil break"?! LOL You came back with a fresh cut and everything!! Love it !! Great Video!!
@antoniocuestarepice786 Жыл бұрын
Bro said "had to take a lil break" = returns with different haircut. LOVE THE VIDS, all the way from SPAIN. I watch your vids at 2x to get a quick recap
@seenaoommen5137 Жыл бұрын
Sir you are amazing. Can't thank you enough for your teaching. Inspiration!
@garrylasaga1550 Жыл бұрын
Still the BEST lecturer in KZbin
@adrianaquirogavelasquez9452 Жыл бұрын
Thank you so much! Awesome explanation. Just an observation/question : Are alpha 1 blockers used for incontinence? Aren't they used for retention instead?
@calloftruth Жыл бұрын
i think alpha 1 inducers retain the urine other hand alpha 1 blockers blocks or stops the activity to treat retention.
@davideserboni8 ай бұрын
you're right
@user-sp8mf1vx6d Жыл бұрын
UNBELIEVABLE HELPFUL!!!!! THANKS A LOT IS THE MINIMUM ...CONGRATS
@zainab7036 Жыл бұрын
🤩🤩🤩thank you so much , i love you Channel . Keep going . May God bless you and your team ❤️
@Arsalan_umar Жыл бұрын
Thanks ❤
@nelsonomondi5941 Жыл бұрын
Nice one
@slowbro- Жыл бұрын
Marvellous! Absolutely Marvellous!
@SadiaZaman-tw7si Жыл бұрын
Really thank you!! You are the savior ,Sir 😊😊
@noornoora688 Жыл бұрын
Thank you so much for this great explanation
@lourock_9 ай бұрын
Thanks this helps tremendously
@spudman3275 Жыл бұрын
love your content bro, you are a wonderful human being. thank you.
@user-ey4hy3le8h7 ай бұрын
Hello and thank you for explaining everything so well. I was wondering how NE and E affects the receptors if they ever do overcome their natural affinity?
@BarrelCollective4 ай бұрын
Where would you fit demetotomidine and clonidine?
@14_usmanarshad32 Жыл бұрын
awesome lecture, 28:21 our cute little sphincter muscle 😂
@EntEmpireTVАй бұрын
God bless you and gives you all you want , see you at 10 millions subs❤
@Muzzamilgola Жыл бұрын
You never Disappoint.. keep it up man ❤❤
@BarrelCollective4 ай бұрын
Getting me ready for CRNA school interviews over here
@amine6005 Жыл бұрын
splendid we need more pharmacology
@shohinsadiev17710 ай бұрын
fantastic lesson
@lennonbruney8591 Жыл бұрын
Amazing video! Extremely helpful
@mutee61368 күн бұрын
beautiful
@doreenm21603 ай бұрын
Thankyou Ninja Nerd
@lamachi.i8458 Жыл бұрын
My pharmacology exam is Thursday👀 Great work keep going 💙
@Sunshine-wc7td Жыл бұрын
Was of great help. Thanks nerdy
@brendaomana85537 ай бұрын
Muchas gracias por sus videos ❤
@user-sm1hc1gl4n5 ай бұрын
We dont prefer alpha 1 blockers forHTN bcz it decreases BP markedly on working at urinary bladder sphincter by micturition is it right concept so we should prescribe it when HTN+ BHP together
@rouaaabdeldaim1920 Жыл бұрын
Life saver fr, bless you man
@layaglynandu.5484 ай бұрын
Thanks!
@doskevin4882Ай бұрын
Best videos out there
@iamsufyanali Жыл бұрын
Sir, you made a mistake at 9:41 when you tell that NE is the 80% released by Adrenal Medulla while it is the other way around. It is 80% EPINEPHRINE that is released by ADRENAL MEDULLA.
@Maya-uy6fb11 ай бұрын
Thanks
@rafaelandrade85866 ай бұрын
thank you a lot
@emmanuelmarychinecherem6320 Жыл бұрын
Awesome!!
@karmagaming7112 Жыл бұрын
Love u 3000 ❤️ We are Ninja Nerds 🥷
@aleyasha31126 ай бұрын
Thank U Boss for Everything ❤❤❤
@samarestephan2485 Жыл бұрын
You are intelligent. Thank you ❤
@vanish3886 Жыл бұрын
Thank you guys
@junaidusmany636 Жыл бұрын
ninja , you are the best . I wish I could be your direct student.
@sandiarajpoot2302 Жыл бұрын
well explained!🙏
@GISdaily8 ай бұрын
great sir
@amandabentley91288 ай бұрын
Thank you!
@sumaiyaparna1056 Жыл бұрын
Can you please 🥺 upload more lecture on pharmacology..
@plamenferdinandov50836 ай бұрын
having the pathogenesis of pheochormocytoma in mind, why don't we use alpha-1 antagonists and but 1+2?
@Md76iran Жыл бұрын
You are fantastic
@TundeEszlari Жыл бұрын
You are a very good videographer.💯❤
@mahzadarjmandi3585 Жыл бұрын
Very good
@CharDavies33 Жыл бұрын
Im on Labetalol for hypertension as mine spikes above 180/120 regularly, currently on 9 tablets aday and have to take extra when I have a hypertensive crisis, I also have Intracranial hypertension and am on Topiramate. Still being investigated for causes Im only 32 though do have multiple endocrine problems, possible Pheochromocytoma or pituitary tumour.
@rizgarali46097 ай бұрын
YOU ARE THE BEST :)
@lobarita Жыл бұрын
Would you hold an A1 blocker if the patient has BPH but is hypotensive?
@lobarita Жыл бұрын
good question
@rahilpatel9686 Жыл бұрын
Give bethanecol (muscarinic agonist)
@charlenemeats770110 ай бұрын
You may be what gets me through school.
@parmidaeelani5719 Жыл бұрын
You are great ! 🤍👏🏻
@RainMist896 ай бұрын
Hello! Love your videos! I think the notes on the website and the written values on the video might include a typo. In lecture and web searching we are given EPI and (80%) produced and NE (20%) in a 4:1 ratio not flipped as shown in the video. Also the notes you give on the website also show NE being produced by the adrenal medulla twice. Not a huge deal but just wanted to give that feedback. There were some other things with other lectures I have noticed (minor details), and if there is a better way to inform about these please let me know!. Great Stuff all in all though!
@meimei9057 Жыл бұрын
Hey Thanks dear!Please teach us Biostat also !
@theresasunkutu99356 ай бұрын
God bless you for me
@BigShaz_ Жыл бұрын
We love you Keep it going❤
@myriambelaiche6907 Жыл бұрын
ur the best!!!!! med-1 student here:)) i literally skipped all my pharmacodynamics classes to follow along with you, and it was the best decision I ever made!
@shafaqsyed4290 Жыл бұрын
Thank you, but u didn't cover the B2 blockers in this video. Are u going to prepare another video for this?
@nicholaskinoti1127 Жыл бұрын
the video was so long Zach had to get a haircut😂😂😂
@deepakrtr4840 Жыл бұрын
No words bro❤❤❤
@user-pu8ow2ky9u Жыл бұрын
ZACHHHHHH THANK YOU SO MUCHH. ITY AINT ENOUGH HERE'S A NON EXISTENT OSCAR FROM ME TO YOU.
@pzahtisham5944 Жыл бұрын
Zack came back after a hair cut 🌚😁
@sagarkhatri7890 Жыл бұрын
can you make some on anti-depressant
@bushramohammedsiddiquebush6640 Жыл бұрын
Sir is Harrison principal of internal medicine 19th edition is good for study medicine ? .... I mean I'm unable to buy 20th and 21st edition .... So is it okay to study from edition 19 ? ... Is there any major difference in these editions ?