How to Optimize Testosterone & Estrogen To Prevent Prostate Cancer (Estrone / TRT)

In this episode, Dr Rand Mcclain and myself (Michael Kocsis), talk about the effects of the hormones testosterone and estrogen on the body, mind, and behavior in those who have passed adolescence.
We dive into the topic of what exactly causes prostate cancer, and how to prevent it.
And What Exactly About Such Activities Impacts Testosterone and Estrogen? When our neurological system is aroused in specific ways, our endocrine system and vascular system are driven to predictably activate or suppress certain hormone networks. Additionally, we go over peer-reviewed research and methods that address the influences testosterone and estrogen have in a positive or negative way.
Estrogen Madness video - • Estrogen and TRT? Low ...
How to Optimize Testosterone & Estrogen To Prevent Prostate Cancer (Estrone and TRT)
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[@keithnicholsmd6896]

Rand speaks of literature. Mike, why didn’t you ask him for the literature to support estrogen management? There isn’t any. If one follows the medical literature, then you know the harms of aromatase inhibitors. Rand doesn’t understand the physiology of testosterone and how it actually works in the tissues. isn’t it interesting that bodybuilders like Arnold Schwarzenegger and Lee Haney, who is an eight time Mr. Olympia didn’t utilize aromatase inhibitors? They didn’t utilize them because they weren’t available until the early 1990s. So you’re going to tell me that a man on a normal dose of testosterone needs one? Testosterone works through its active metabolites. It doesn’t act as just testosterone in many tissues. It Has to be converted into its active metabolites. When you raise testosterone, you raise levels of the active metabolites because that’s how testosterone works. Rand treats, the bodybuilding world, and that is not the testosterone replacement therapy world. There is no literature to support what he is saying none at all.

[@dlindo8892]

Yeah, but Arnold was known for using primobolan which lowers estrogen.

[@AbrahamKryger]

I have noticed that many physicians who prescribe testosterone for their male patients do not check E2 levels or DHT levels. If they did then they would be able to tell when too much testosterone is being used and converting into estradiol. Simply measuring blood levels 4 days after the injection will establish hormone levels in the physiologic range. Very interesting approach to the use of TRT for men.

[@wrathchild8920]

I'm on androgel. 2 pumps in the morning and 2 in the evening. My test hovers around 600ng total/150pg free. Total estrogen 255pg, estradiol 33pg. My NP put me on 1mg of anastrozole per day, and although my mood, energy, and emotional state has improved, my body feels like I'm 80 years old. Pain in every joint. Dry eyes and skin. I haven't had my estrogen tested since, but I feel like it's gonna be crashed. I'm kinda ticked off.

[@BobFon71]

I’m taking Testosterone shots for 7 years in and out … I’m 6.0 and normal 200 lbs. But because of Testosterone now I’m 52 years old and crazy 330 lbs. I hold lots of water and I don’t feel the Testosterone benefits … anybody can help me with this ? My estrogen is ski high. Thank you. Roberto from Orlando FL

[@Giovanniir]

Dr. Rand suggests using DIM to manage E2, but DIM is also known to be an anti-androgen and downregulates androgen receptors. So, how can this affect on a TRT?

[@block2129]

Is there a DIM starting dose to titrate from?

[@georgetoul]

Estrogens are also pre thrombotic

[@paulhogan1938]

Calcium D Gluterate is very expensive in UK and i have been taking 1000mg per day for months and has done abolutely nothing for my E2 levels, not touched it at all. I was told need to take at least 2000mg per day which works out around £18-20 every 2 weeks. Starting on AI and see how it works out for me.

[@lennoxmate4064]

I struggle to balance my oestrogen with Anastrozole (Arimadex). I either end up with it too high or too low

[@_m_K_.]

Thank you for this conversation. I don't know why the AI debate is so polarizing. Like all things hormone related, your milage may very. Some men get on trt/anabolics and lose their hair, or hairloss accelerates. Other men have minimal or no hair loss. Estrogen is the same way. Some men have bad signs and a high numbers, some guys have bad side effects on very low E2, and some men seem to have no issue irrespective of numbers.

[@dlindo8892]

Great content. Dr.Rand knows his stuff. Thanks for this one! 👍

[@7THxSIGN]

This is the only doctor I listen to. Great video and information as usual.

[@christopherthomas6493]

Credit the host here with Dr Rand with great questions for this great conversation

[@SD-unlimited]

I’m struggling to find an answer to this question: do any men stop TRT as they get to an advanced age?

[@gozitan5]

Great presentation…real informative. How many mg’s of DIM daily please ? Thanks. 👍🏼

[@erick6102]

Seems like this is a good reason to start TRT at low levels and slowly increase to dial your numbers in

[@Kampup]

Michael does your clinic routinely check your clients for all the things you spoke about in this video?

[@scooodlescorn4070]

I research HRT (testosterone, estrogen, prolactin, etc.) every single day.

[@simonstone7099]

I would be very curious to know what Dr Rand takes as his protocol and even yourself Michael. I have understood from previous videos of Dr Rand that he has touched on symptom resolution for a lot of patients only happens once they hit 1500+ ng/dl so makes me curious if this is what he shoots for himself personally? I don't believe Dr Rand does daily microdosing for himself, perhaps twice per week?