Be Proud of Your High Cholesterol? | What the Fitness | Biolayne

[@isthatharrasment]

I wouldn't take nutrition advice from somebody who looks like they lost their life savings in Vegas

[@greggbambu411]

He has the credentials to back it up. Look him up

[@isthatharrasment]

@@greggbambu411 That means a lot less than you think

[@Lovelyone1]

My dietician says the same thing and she has a doctorate. This guy hasn’t done the work that she has done but I guess you like people who yell because that must mean he knows what he’s talking about.

[@knoxvillehill]

@@greggbambu411 but he still looks like they lost their life savings in Vegas so who cares

[@knoxvillehill]

@@Lovelyone1 layne norton just demolished his bs .. just watch it again

[@Physionic]

I agree with everything you said, Layne, but it might be nice to offer some references so people who aren’t familiar with you are able to notice the difference between your claims and nonsense. Selfishly, I’d also like to see the references on inflammation and particle size. I have a few I use, but more is always better. :)

[@JWB671]

It’s all genes… my particle size is tiny and my inflammation markers are zero. LDL cholesterol on keto was 240 on Mediterranean and low dose meds it is 65.

[@_negentropy_]

Nic have you covered this on your channel? I’d love to hear your take on the different LDL types. I’m also curious if hrt can effect either type but that might be beyond your scope.

[@Physionic]

@@_negentropy_I’ve covered it, including multiple studies - the most convincing is the MESA study.

[@brucejensen3081]

Regardless of particle size, excessive ldl is a sign that something is off. It's just that the fluffy ones are more effective at countering the problem.

[@Enugers]

I'm studying do become a nutritional therapist and they also teach that inflammation is the root cause of evil, not specifically LDL cholesterol. Would love to see the studies you reference Layne, just to have something to concrete I could use to question my teachers. Edit. I watched some of Physionics videos on LDL and inflammation and pretty much got the answers I was looking for.

[@seanpannebaker6404]

FOR the algorithm and Human Randomized Control Trials!

[@MisterWealth]

I'm not convinced this guy isn't Sasha Baren Cohen in disguise.

[@espenstoro]

1: 2: 3: 4: The algorithm.

[@tsebosei1285]

Thank you Dr Layne I used to follow Ben and all the Keto doctors not anymore now following human randomised trials

[@Chris_P_]

Same here and I am so appreciative of Dr. Norton debunking Keto and saturated fat myths.

[@serotoninsound6253]

These advices are so dangerous!! THank you for setting the records straight Layne!

[@applerunner1184]

I love it when he goes after the LDL and seed oil crazies! 😂

[@antmanandthecod6073]

If only all the best athletes in world knew it was seed oils damaging Their performance

[@killmat1c]

Lol Isratel and Norton are making toilet paper out of seed oil quacks these days.

[@terminator3728]

kzbin.info/www/bejne/iZ2WmGR6oZl0gqcsi=h8J7VbD7QWb-hN3P

[@terminator3728]

kzbin.info/www/bejne/iZ2WmGR6oZl0gqcsi=h8J7VbD7QWb-hN3P

[@tuckstar]

One day you'll realise that LDL isn't the bad guy and is beneficial, just like insulin.

[@tor5457]

He regurgitates all the talking points of the pro-cholesterol/saturated fat gang.

[@srleplay]

Don't worry Howard Wolowitz will stop this shit once he realizes being keto influencer won't help him with the ladies

[@geraltofrivia586]

🤣🤣🤣🤣🤣🤣🤣🤣🤣

[@watsonkushmaster3067]

I thought its tom from jujimufus channel

[@SLude480]

His analogy would betray their belief that keto and carnivore reduce inflammation. If cholesterol is there because of inflammation(the “firefighter”) then why does it skyrocket when you eat in a way that is supposed to be anti inflammatory? 😂

[@Jojo-o6o6w]

my blood markers for inflammation went to normal when I went carnivore. my partner started the same time as me and to his surprise his doctor told him his hemochromatosis went away

[@ve_rb]

@@Jojo-o6o6wway to miss the point entirely

[@ve_rb]

@@paulc5389 who knows. The fact of the matter is meta analysis over meta analysis has shown time and time again again that LDL increases risk of CVD

[@ericglass1270]

Layne totally missed his opportunity to tell Ben "Ben if you could reach out and leave a comment.....forrrrrr the algorithm"

[@LindaSavoryPizzo]

🤣🤣🤣

[@ÁzsiábaSzakadtam]

One of the 3 sane health educators online. Layne that is.

[@jordanhardy8987]

It’s Friday and I know what time it is.

[@byNetak]

time to watch the fitness -> biolayne

[@ripxrip]

Thanks for the videos. Legit changed my life

[@klle3419]

Hope you listen to and connect with Dr Alo - an actual licensed cardiologist in this space - i’m so grateful to both of you for shutting down the BS noise all over you tube

[@ldproc0]

Totally correct. Just a dumb MD here. Thanks for speaking data!

[@nocifer]

"You don't _feel_ heart disease, until it kills you." Had me cackling 💀

[@AndresVieyraOficial]

Great video Dr. Layne! It'd be great if you can do a video explaining how Mendelian randomization works :)

[@alfonso365]

Damn, these zealots sound so confident when they spew that shit out. Shameless!

[@ghost9-9ghost]

Yep...Chaffee...gundry....Norton....al the little infkuencers....bunch of narcissistic zealots.

[@kieranwhittemore1010]

Awesome content Layne

[@Galarid87]

Fuck that, I'm proud of my high carb low fat high protein diet. Because it has me jacked and lean.

[@brucejensen3081]

Yeah but a moderate macro diet would probably have you just as lean and more jacked.

[@C0d0ps]

@@brucejensen3081 Says who? If you meet the minimum grams of fats and enough protein. Then you can use either carbs or fats as an energy source.

[@davesmith826]

Careful. I was also on such a diet and also jacked - until I ruptured an achilles tendon. Doc said deficiencies in fats can weaken tendons. He wasn't wrong.

[@mikehawk302]

@@davesmith826did you also happen to take cipro?

[@williamhartman9]

Does it ever make you feel bad to shatter these poor people’s dreams and fantasies like this ??? I’m so glad we have credible people with the balls and integrity to give us good information. Thank Lanye

[@mattTHEEgreat]

He looks like he sells creatine to teenagers at the gym and says it's tren.

[@cheliospanama9786]

Great Video! Thank you 🔥👏💪🫶

[@thegalaxycosmos7703]

Genuine question, I want to get your input on what you think on this based on the research, because I trust your expertise: -Is there any kind of difference between the effects on LDL cholesterol from different sources of saturated fats like cheese, milk, eggs, vs different kind of meats? Are some better than others or is the effect on LDL constant across all saturated fat sources?

[@gerardmillar1680]

Great video! One thing I would have love Layne to add here is how does LDL cholesterol compare to say - total cholesterol, HDL/LDL ratio, relative risk factors compared to other variables such as blood pressure, high triclyerdies etc. The reason I ask is when I did keto and lost 30 to 40kg of weight all blood markers got better excecpt one. I mean literally reversed 7 od bad readings. TTriclyerdies got better over time, fasting blood sugar went down, blood pressure went down slowly, liver enzymes got better GGT, AST, and ALT. The one that utterly refused to budge was LDL cholesterol. Add to that unlike everything else which was a nice linear correlation - every time I measured the bloody LDL thing it was yo yoing all around the place. Sometimes normal, sometimes high.

[@michaelhoile1369]

Great 👍 video 🎉🎉🎉

[@LandOfTheFallen]

He’s repeating Dr. Ekberg’s argument word for word >_>

[@StraightEdgeJunkie]

There's another cuckoo hack Layne should cover.

[@NONcomD]

Layne, mendelian randomization is not a tool without its drawbacks. The genes responsible for lower LDL might also.impact cardiovascular health in different ways. Pleiotropy is a real thing happening in these studies.

[@leemanwrong]

Mendelian randomization is just another form of epidemiology so unable to inform on risk or cause and effect.

[@wread1982]

3 of my friends in their early 40s had heart attacks and 1 died and the other two needed multiple stints so at last year at age 40 I put myself on 10mg Crestor, aged garlic supplement, bergamot green tea, flushing niacin. My dad had a heart attack at 55 they put stints in and he’s been on Lipitor ever since and he’s 75

[@wread1982]

I also switched from butter to olive oil

[@alexhansen2102]

I would love to see a study looking at keto/very low carb diets where they eat exclusively unsaturated fats like avocado or olive oil.

[@scottlarsen1512]

I would still love to see an extended chat between Layne and Bart Kay. As I understand - Bart has extended multiple and open invitations to Layne, so other than being concerned about his position, I don’t see why he is not looking to take Bart up on this discussion. In the future, it’s going to be interesting to see what positions Layne walks back (if any).

[@scottlarsen1512]

@@RaveyDavey - yes I did not say they should debate. I intentionally said an extended discussion. This is a nuanced and there is not consensus, either in the scientific literature or the leaders in this space. Science is evolving as theories are tested. From my observation, many of the clinical trials that Layne sights, have major statistical issues. As I am not an expert, I don’t plan to comment on the specifics, but, someone like Bart Kay, who holds degrees specially in the area Layne is discussing and also in the mathematical/ statistical inferences would certainly add credibility to Laynes position if he is correct in his assertions. Or not. Once again, the fact Bart has reached out to Layne and this is not reciprocated clearly shows Layne is not 100% confident in the science he is using (in this and many of his other clips). Also, it is an indication that there may be something to hide/ not disclose. At the worst it also may show Layne does not deem a peer worthy of a discussion - you can make your own inference to what psychological states this behavior may indicate.

[@scottlarsen1512]

@@paulc5389 agree

[@739jep]

Bart Kay isn’t a serious enough person to have a discussion with. People have limited time.

[@Andrew-qc9xw]

G’day Layne, could you do a video specifically about this obsession with “INFLAMMATION” that everyone seems to have. It seems to me it’s a buzzword that gets thrown around a lot. Could you explain what it is and why it seems to be such a big deal,please? If you’ve already done this, could you please share a link? Kind regards, Andy

[@brucejensen3081]

It's damaged that needs to be repaired. If it's chronic, it doesn't get a chance to be repaired

[@blarghmcblarghson1903]

Inflammation is the body's response to damage, it's caused by the expanding of capillaries to allow more blood (and all of the immune cells and building materials floating around in it) to flood into the damaged site, which balloons (inflames) to accommodate all of this expanding and flooding of blood; the health gurus look at inflammation and go "oh, there's inflammation every time there's an injury, it must be the inflammation causing the damage!", which is ironic, because Ben Azadi's cute little analogy about blaming fires on firemen is _exactly what he and his ilk are doing._

[@StraightEdgeJunkie]

@@blarghmcblarghson1903 You're so right, and they all do this, haha. Hell, I feel like most of them use the same fire/firefighter analogy too. These people are all the same person lmao. It's so strange and I sometimes with to understand why this happened.

[@Andrew-qc9xw]

@@blarghmcblarghson1903 that’s how I understand it,too. Thank you.

[@locomike102]

Muh INFLAMATION!!! I don't know what that actually means but everyone says that's why I need a bypass--not the 40 years of cheeseburgers!

[@AislingDonohoe]

Layne, could you please address Simon Hill’s critique of your recent protein video?

[@illestdomer2005]

Those lipoprotein A tests are pretty expensive too. Repatha is also expensive but crazy effective at lowering LDL if you have statin intolerance.

[@donwinston]

It is very disturbing there are so many people willing to dismiss the recommendations of health authorities all over the world and believe nonsense from a few social media "influencers". It has become a significant social pathology in today's society.

[@CharlieFader]

@@donwinston contrarianism sells, especially now. The message of “everything we knew was wrong” is very friendly for people that knew nothing anyway.

[@ghost9-9ghost]

​@@CharlieFaderexactly....one day in the future they won't use "dunning kruger"...they'll say "Terrence Howard Pretentious Delusion Syndrome" or something....

[@donwinston]

@@paulc5389 No. Cholesterol(LDL) created by your liver is certainly BAD for you. It is not remotely debatable. Dietary cholesterol on the other hand is complicated. Some people do not absorb it and their cholesterol levels are unaffected by eating cholesterol high foods. But many people do absorb it. Some are hyper absorbers where dietary cholesterol will significantly affect their blood cholesterol levels especially if it is high to begin with. I find it disturbing that you are so readily excepting of anti science nonsense. Scientists and doctors are NOT incompetent and corrupt. They have not been feeding you bogus information for the last 100 years as you seem so ready to believe. New science rarely "replaces" old science. It adds to it!

[@donwinston]

@@paulc5389 100% horse shit. Your LDL cholesterol cannot be too low. FACT: The optimal level of LDL cholesterol to avoid any chance of cardiovascular disease is LESS THAN 60 mg/dL. High levels of LDL cholesterol is a REQUIREMENT for cardiovascular disease and not merely a risk factor. No reputable researcher on cardiovascular disease debates this.

[@CharlieFader]

@@paulc5389 only quacks believe the nonsense you're claiming.

[@joerockhead7246]

thank you

[@neven8ivan]

If you look at the blue zones where people live to over 100 years old the 2 things they have in common are high ldl cholesterol and low A1C . High ldl can be a risk factor if other markers are off . But if you have high ldl and low lipoprotein a ,low triglycerides and low a1c then it is now a risk factor

[@nichtsistkostenlos6565]

No, this is not true. People that live to 100 years old, on average, have higher LDL than those that die earlier for multiple reasons. First, the longer you live, the more likely you are to develop high LDL because of the near inevitability of heart disease in humans. Second, people that are very sick in their old age tend to have low LDL because very low LDL is a common symptom for those that are very ill. Third, we don't have good data on historical LDL for people that live past 100, but in all likelihood for the majority of their lives they did not have high LDL. Fourth, we have actual Mendelian randomization trials that show people that had high LDL throughout their lives have significantly higher risk of developing ASCVD and having cardiac events absent these other factors that you're mentioning. This completely trumps the observational studies of blue zones because the Mendelian randomization methodology comes as close to proving causation as we possibly can in these circumstances.

[@neven8ivan]

@@nichtsistkostenlos6565 read my friend.....read . www.ncbi.nlm.nih.gov/pmc/articles/PMC10828184/#:~:text=All%20but%20two%20of%20the,odds%20of%20becoming%20a%20centenarian.

[@neven8ivan]

@nichtsistkostenlos6565 Russia and Japan have the highest consumption of meat in selected countries worldwide. 96 percent of consumers from Russia as well as 96 percent from Japan state that they consume this kind of food. Japanese people eat the most meat with high ldl and live tge longest. High ldl is only bad when your A1C is high. Typically when a1c are low tge ldl particul size is not small density

[@GJ_0008]

Love watching your videos but (maybe you have covered this in others vids?) what does this all mean in practice? All these terms and markers and tests etc. don't mean a lot when you don't have access to these tests and don't have a background in the science (or have time to learn properly about it all!). I consume a fairly healthy and balanced diet (I think) of meat, fish, fruite and veg and carbs. I like my mid morning boiled eggs and love Greek yogurt! But is that spiking some markers unbeknownst to me. I live in the UK and think if I went to my NHS doctor to ask for these tests they would say not to worry and they're not available on the NHS if you look young(ish! 😂) and healthy. Thanks very much.

[@PSA78]

I wonder what they ate before if they can actually feel their health improving with that diet, I'm guessing dart frogs. 😂

[@nekowolf583]

Funny that when he said “You probably feel better, don’t you” the captions read “don’t know.”

[@henrituhola]

Where are all the comments claiming LDL is good? There should be at least 10 by now. 😮 Layne did you piss them off?

[@stevenedmunds2018]

I know you shouldn’t judge a book by its cover but I wouldn’t trust shit Wrong Jeremy says based off his book cover.

[@bi5319]

What carb sources does Layne recommend the most besides fruit?

[@GeorgeMcDougall-gz4tp]

Whole grains etc because there higher in fiber

[@derekw9405]

Not sure what he would recommend but you cant go wrong with whole grains, Legumes, and veggies

[@mikehawk302]

@@GeorgeMcDougall-gz4tp or sweet potatoes

[@chibbyylol]

Be proud of your high body fat, be proud of your high cholesterol… What’s next?

[@alfonso365]

Be proud of your high blood pressure... because dead people have 0 blood pressure... so the higher, the better.

[@tito5428]

Don't be proud of your gender

[@all462]

bE pROUD oF dYING yOUNG

[@davesmith826]

@@alfonso365 This reminds me of my favourite carnivore / keto myth: people who die often have low cholesterol, therefore low cholesterol is bad. The real reason is instructive: cancer feeds on cholesterol, which drives it down just before death.

[@S7320]

@4:17 chirp. Layne is a real one.

[@T04st0]

Here's your lousy comment, you damn algorithm. Seriously though, great content, big homie!

[@HSLSFirst]

That Ben guy spits out a lot of BS. I’m glad there is Layne to set the facts straight on YT.

[@Christopher-md7tf]

This dude looks like Conan's "trainer" from his gym remote with Kevin Hart 😂🤣

[@mikaelmagnusson3225]

Make a video on the China Study på Campbell. He smash animal protein, Dairy and salt.

[@leemanwrong]

No point, Campbell cherry picked his data so the study is meaningless.

[@jeffmurphy6892]

here is a comment for the algorithm

[@rn5697]

Cholesterol is ok ( if you are not hyper responder) Inflammation can cause problems Saturated fats can cause problems Did I understand good?

[@CharlieFader]

LDL should be low, having some dietary cholesterol probably won’t raise LDL much (there’s some nuance there) but in general saturated fats (and trans fats) will.

[@jgreasy1213]

If I close my eyes I feel like Charlie Day is yelling health advice at me

[@johannesvenezian642]

He also got the very basic idea of cholesterol as being there to "rescue the endothelial cells" as if these are firefighters, while it is the immune system which reacts to the oxidated LDL particles trapped in the subendothelial space...

[@sideaffects4757]

how is a random trial good science tho? the mendilian randomized trial doesnt seem like a concrete trial because your getting peolle who drink alcohol, smoke obese which also greatly affect the LDL-C?

[@saintedith]

Not sure where but weeks ago I saw someone explaining a recent study indicating that people with ldl less than 160 are showing better cardiovascular health than those with less than 100, suggesting that it is better to be above 100 but less than 160. Can someone confirm?

[@plaidchuck]

It was basically a bell curve distribution

[@CharlieFader]

@@saintedith the reason matters. For example malnutrition and serious illness can lead to lower LDL.

[@xanxus8272]

I didn't know Sacha Baron Cohen had a twin brother

[@lucaslouzada44]

If there’s still people talking about a flat earth after the XVII century, imagine how much longer people will be talking about saturated fat, LDL and inflammation…

[@CharlieFader]

@@lucaslouzada44 unfortunately contrarianism and anti-science are more popular than ever.

[@danielmason8574]

One possible reason is the misnomer of "science of human nutrition ". Just when we think we understand, much of it is turned upside down.

[@CharlieFader]

@@danielmason8574 like what?

[@danielmason8574]

In the 70s, 80s, 90s decades, low-fat was one key to health. Now, there's much evidence leaning toward low carb/high fat consumption for a few beneficial reasons.

[@CharlieFader]

@@danielmason8574 actually even from the Angel Keys days (40s, 50s) the focus was on saturated fats and cholesterol. There’s always refining of the details, like going from total cholesterol, to LDL and more recently to ApoB and learning about Lp(a). But the science didn’t really change that much, but more details were added. There are always diet trends based on macros, like low fat and low carb, but macros don’t really matter that much on their own. The quality of the diet and the calories are way more important.

[@nichtsistkostenlos6565]

Mendelian randomization trials have absolutely settled this debate just burying it 1000 ft into the ground. High LDL and high ApoB levels are absolutely causal for ASCVD, we can say this with like 99.999999% certainty. With the number of trials that have been done looking at this from damn near every angle and removing basically every single confounding variable the chances of this being wrong are so low that we know this with as much certainty as anything in the scientific literature. There may be a tiny minority of situations where this is not the case, but for the vast, vast majority of the population this is like on the level of knowing that atoms exist and contain protons, neutrons, and electrons. If you know anything about Mendelian randomization and the mathematical probabilities at play here, you would quickly dismiss basically everyone saying the opposite.

[@pattybaselines]

The editing is insane lol

[@AstonAcademia]

"That's enough Ron Jeremy" 😆😆I grew up in that era and knew Ron very well.

[@aisac21]

Guys, that's Ben Stiller, he s just trolling, don t believe what he s saying😂

[@PeerGynt-j3t]

For the algorithm!

[@Shraken]

The guy looks like a Sasha Baron Cohen character.

[@XYNTEN]

Layne really likes his mutual funds.

[@user-ii7xc1ry3x]

We need a new example. That one is PERFECT, but I'm afraid many people will fail to truly understand it despite its simplicity

[@stephaniehafner333]

What do we do if we have high ldl aside from avoiding saturated fat ?

[@AliceFarmer-bg4dw]

So what causes heart disease?

[@plaidchuck]

Plaque build up in arteries, congenital defects

[@leemanwrong]

Most likely blood pressure and turbulence as atherosclerosis is only found in the arteries in predictable areas where pressure and turbulence are the highest.

[@Ivan_Mohnke]

If cholesterol is a bandaid, and it’s elevating, means there’s something he’s doing is requiring that band aid

[@mevensen]

Just one pedantic point. You can “feel” some heart disease before a true cardiac event in the form of angina.

[@andrewzach1921]

Comment for Al Gore's cholesterol

[@raullodos4649]

He looks like Sharon Stones boyfriend on the film "Casino", played by James Wood. I bet this guy has an extensive leisure suit and white patent leather shoe collection at home.

[@Alais_NorizaXIV]

Dude looks like a Sacha Baron Cohen role xD

[@mrsbryant]

Can you review smelly belly’s new video ?

[@gokukakarot1855]

For the algorithm

[@ColdRunnerGWN]

I always wonder if the people who wear those tinted glasses are hiding blood-shoot eyes. I had a couple of teachers growing up that did that because they were huge drinkers.

[@ho2673]

4 the algorithm 🎉

[@marcdaniels9079]

Ben sounds like he is doing a very poor impression of Christopher Walker 😅😅😅

[@StrengthAndConditioning61]

"Great job you probably feel better don't you?" "Why yes this new heart valve is fantastic and I don't care about my high blood pressure either! It's great!"

[@arronmason6692]

Natural selection at work.

[@DonnieDarko727]

"Penetrate" the endothelium. 😂

[@lifepolarized]

i haven't seen people with too high hdl?! is anyone here?! :))

[@rwh4114]

Pretty sure that's Borat.

[@waynegolding14]

For algor!

[@DEFPIT]

For Al Gore!!

[@Jojo-o6o6w]

there are renowned cardiovascular surgeons who are experts in this, unlike you, who agree with carnivore.

[@K4R3N]

For the algo

[@testitestmann8819]

This week in: what the fatness

[@adim00lah]

I've told people this for YEARS, it's not cholesterol that raises your cholesterol, it's saturated fat. Some saturated fat is good for you, like the c15 that's in butter, but moderation is still important. No surprise, the Tsimane tribe in the rain forest of Bolivia which has the lowest levels of atherosclerosis of any demographic known to science, eats a diet low in saturated fat, about 11 grams per day which is 1/2 the rda of dietary guidelines. Inuit mummies were riddled with atherosclerosis, so all this crap about seed oils or processed foods being the only culprit to atherosclerosis is pure bs. Any form of saturated fat, regardless if it's from human or plant origin can and will clog your arteries if eaten in excessive amounts, even for those who have genetic adaptations for this diet like Inuits. There is zero evidence eating a diet high in saturated fat will protect your heart against athersclerosis, there is no demographic you can show that eats a diet high in saturated fat that has very low levels of atherosclerosis.

[@nicolebrown9262]

It would be nice if you just stuck to the science, rather than making personal attacks on the guy's appearance. Keeping it professional would have been much better.

[@richardbruyere9523]

Since 80% of cholesterol is produced by the body I’m going with whatever stops arterial inflammation. No sugar.

[@leemanwrong]

Plus cholesterol travels all throughout the body so if it was causal we should see atherosclerosis all throughout the body however we only see it in the arteries in very predictable locations, clearly the cause is something else.

[@Kaztrofy]

I thought it was an Ali G skit.

[@karwask1]

Hi Layne, unless I missed something, I'm still really surprised that you have not responded to the Simon hill, proof podcast challenge to your take on protein and healthy aging, a new study. One of the reasons I respect you as much as I do is that you are a person who has shown that you're willing to relook at evidence and change your mind if it's called for. it seems that in your analysis of that new study, you might have missed some things and it wasn't just Simon Hill pointing it out, it was people following you pointing it out right there in the comments section of that same video and since that, in other videos as well. So, I look forward to you eventually addressing this issue. It would be unbelievably disappointing if you just leave it be an enormous blow to your credibility. Thanks again for all you do.

[@locomike102]

That guy looks super healthy! Whatever he's doing, we should all do it without investigation!

[@tallesttreeintheforest]

thank you layne, i supplement 3 tablespoons of vegetable oils each day because of you. it lower my cholesetrol and im so much healthier.

[@idcharles3739]

What is lifelong LDL exposure? And how can you do a randomised control trial for a lifetime in the last 20 years? I'm calling BS biolayne

[@nichtsistkostenlos6565]

We have reliable measurements for LDL, ASCVD, cardiac events, and genetic defects that cause high LDL going back literally 70 years.

[@rualablhor]

So...what exactly is high cholesterol ldl-c ...100, 150, 200+?

[@illestdomer2005]

Typically, you want your LDL below 100. If you have cardiovascular disease, diabetes, etc., you want it below 70. Goal posts continue to shift though. You might see a target LDL of 50 or so now.

[@rualablhor]

@@illestdomer2005 I think that is the standard US medical advice, which I personally don't buy...Much like US standard A1C guideline, I find it unreliable.

[@illestdomer2005]

@@rualablhor in what way? You think it’s too low? Too high? Without having investigated it, I imagine it is likely based on the same data observed from these randomized control trials.

[@rualablhor]

@@illestdomer2005 In regards to A1c, it should be lower, currently it's 5.7 for early stage pre-diabetes. I think it should be ~5.4. Ldl-C, I would go higher...I try to hedge around 130's. A good nutritious, decent protein (0.8g per lb) diet with ok cardio/activities usually will land you above ldl-C 100 fwiw

[@CharlieFader]

It really depends on the level of risk that you’re comfortable with. While most guidelines will say under 100, if you ask most well-known cardiologists and lipidologists they will say that In order not to lay down plaque you need an LDL under 70, or even under 60.

[@Halli6163]

algorithm

[@Corkfish1]

Mine apparently gave me heart disease even though all my inflammatory markers were low.

[@OsAbliNgin911]

Did you take the hot shot?

[@Corkfish1]

@@OsAbliNgin911 Unfortunately. But I had issues before COVID

[@waleedabbas4996]

@@OsAbliNgin911 How would a covid vaccine increase plaque in your arteries? 😂

[@xoranginho]

@@waleedabbas4996 because joe biron obamna WEF bill gaytes something. people just want to reaffirm their believes through anecdotal „evidence“.

[@CharlieFader]

@@waleedabbas4996 apparently it’s the cause for everything bad 😝