Fischer to Haworth and Chair for Glucose and Fructose (Vid 5 of 5)

[@ellenschrader7971]

I'm from Germany and even I was able to understand everthing. You helped me so much for my exam tomorrow. Thank you so much.

[@morgansampi5336]

+Ellen Schrader ICH AUCH!

[@bikemesi]

Ellen Schrader Abitur kann kommen :D

[@undeadscene8552]

Warum sind Lehrer so inkompetent >.< xD

[@andyfreeman3824]

@@undeadscene8552 besser verstanden als in 4 Stunden Unterricht xD

[@elauera]

Genauso :)

[@DINESHKUMAR-rw7hd]

Hawroth projection had been something to memorise for me . Thanks for revealing the actual visual concept. Thank you

[@Leah4sciMCAT]

You're very welcome!

[@vmsc7060]

You are such a life saver! You are not only preparing me for the MCAT but helping me tutor students along the way!!

[@Leah4sciMCAT]

Awesome! Glad I could help

[@leandrodias2050]

From Orgo to Biochem to the MCAT. I’m a lifeguard, but you’re the one saving lives!! 👏🏽🙌🏽

[@Leah4sciMCAT]

Lol. Thanks so much! Glad you found the video helpful.

[@kimhoang3860]

your videos are the best Leah. I survived OChem because of you and now I am taking Biochem and watching more videos from you. Thanks a lot!!!!!!

[@Leah4sciMCAT]

+Kim Hoang so happy to hear. Thank you and glad the videos are helping

[@pearlfaraj8919]

Your chemistry videos are the most helpful on KZbin! I understand chemistry because of your videos :) Love that your drawings are fast and that we don't have to wait for the drawing of lines/words or erasing like Khan Academy videos - can't stand them!

[@Leah4sciMCAT]

+Pearl Faraj thank you! glad you're finding them helpful

[@doggysadventures5726]

Simply the best video on youtube! Such an amazing and clear explanation😊 can’t be grateful enough for your lifesaver videos🙂

[@Leah4sciMCAT]

Yay, glad it helped!

[@bwbenson32]

A clear explanation of a complex subject. Well done. Thank you so much for taking the time!

[@Leah4sciMCAT]

+Branden Benson you're welcome. glad to help

[@archiecabachete2372]

i'll be having my exam with this topic next week and this is really a great help ! thanks a lot.

[@Leah4sciMCAT]

+Archie Cabachete awesome! glad to help

[@nasserBack]

This is a video that helped get An A- in my organic chemistry class in university. I really love all your organic chemistry videos. You saved my life in both organic chemistry 1 and 2. Your explanations are beyond clear and understandable and my tuitions money should go to you not to my professors. Thank you Leah for this channel. You are a gift from Allah :) Cheers

[@Leah4sciMCAT]

Thank you very much for your kind words!

[@pattiecordova]

OMG... this brings back memories. Thanks for the breakdown.

[@Leah4sciMCAT]

Pattie Cordova Thank you :)

[@yuzu8284]

God bless you you are a queen of chemistry!

[@drkochvlogs8764]

What is the software you use for ghis online teaching You are doing a great job,👍👍

[@Leah4sciMCAT]

Awww thank you!

[@psiloveyouscrap]

Good job demonstrating this. It brought back memories from long ago.

[@Leah4sciMCAT]

P.S. I Love You Scrapbooking Thank you

[@jessicamitchem7046]

This video helped me so much for biochemistry! Thank you so much!

[@Leah4sciMCAT]

You're so very welcome!

[@MonkeyDLuffy-xr4fl]

Your videos are literally saving my life

[@Leah4sciMCAT]

Glad the videos help :)

[@charlesbeach575]

Not premed, but a very thankful nursing student! Thank you so much, this video was so helpful!

[@Leah4sciMCAT]

Thanks for the feedback! You are very welcome.

[@rlx5000]

Thanks a lot Leah, i remember back when i was on organic chemistry that i watched a lot of your videos. Now that i got to remember some stuff for biochem i came across to your channel again and you helped me once more

[@Leah4sciMCAT]

Awesome! I'm glad to hear that my resources are continuing to help you!

[@SahilShaikh-te2im]

One of the underrated channel should be More subs.

[@Leah4sciMCAT]

Awww, thanks!

[@oyvavoyable]

Thank you so much- you taught me more in 15 minutes than my professor has taught me all semester!

[@Leah4sciMCAT]

You're welcome so much! Glad I could help

[@sfindaa8523]

Thank you! Thank you!! Thank You!!! I liked and subscribed. You just made my night easier. Home work due tonight and exam in 3 days, this was very well-explained. Thanks again

[@Leah4sciMCAT]

+Briste Belle oh wow glad to help

[@sfindaa8523]

Please, I have an exam on Wednesday (tomorrow), can you clarify how to recognize enantiomers, Diastereomers and Anomers in monosaccharides? Please reply, Thanks

[@Leah4sciMCAT]

+Briste Belle If you're asking for a video series I'm sorry but I won't have those up by Wed

[@sfindaa8523]

Leah4sciMCAT Never mind. It was this past wednesday and no not a video. I was thinking you could send a brief reply here..but thanks anyway. The video was helpful

[@marks762]

This was amazingly clear and saved me so much time. THANK YOU SO MUCH!!!

[@Leah4sciMCAT]

+Mark S you are very welcome! I love sharing tricks that will save you time on exams

[@AshleySaunders]

wow that was so informative and seriously even I could follow along, this was not my thing in school!

[@Leah4sciMCAT]

Ashley Saunders Thank you. I found this really tricky in orgo/biochem till I figured out the trick. Glad you found it helpful

[@crocketmeow]

This was very helpful concerning carbon 5 of glucose orientation. I had a hard time explaining that exception to someone. Thank you for clarifying.

[@Leah4sciMCAT]

+crocketmeow glad to help

[@Ismben22]

Thank your for the clear tutorial ! please correct me if i'm wrong. when you say [05:30] : when i draw Alpha, it (OH) goes down, and Beta, it goes Up. this work only for D-glucose, for L-glucose it's the opposite. the position of your OH on the first carbon depends on the position of the carbon 5. if you want an alpha, then put your carbon's 1 OH at the same side of the carbon's 5 OH if you want a Beta, then put your carbon's 1's OH at the opposite side of the carbon's 5 OH

[@Leah4sciMCAT]

+ismail ouriaghli (isbenj) The entire trick all the way up to that point is only for the D-glucose

[@wittyusername9544]

Leah you are the best at tricks. Thanks.

[@Leah4sciMCAT]

Thanks so much :)

[@talbd1884]

Hi leah, first of all, you are AMAZING! Second,just letting you know(if you didn't) , some youtube's accounts uploaded THIS video from your chanel to theirs FYI

[@Leah4sciMCAT]

Thanks for your kind words and thanks for letting me know

[@MostlyGamingVideos]

From a college freshman currently in biochem: Thank you!

[@Leah4sciMCAT]

+MostlyGamingVideos You're very welcome. Although I'm curious, how is a college freshman in biochem? Most of my students take biochem in their junior or senior year

[@thjthj3279]

t

[@MostlyGamingVideos]

Leah4sciMCAT I am taking intro to biochem courses and labs, they're required for all biochem majors at my school

[@subhajeetlahiri6773]

@@Leah4sciMCAT We ,in India,are studying this in grade 12 in chem (in the chapter biomolecules) though we have taken phy ,maths , chem as our main subjects and are preparing for an engineering entrance test.... Really messed up

[@Angelica-pw8mg]

I was panicking because we have an activity later regarding this and I don't really understand my prof so I was looking for a tutorial here in YT and found this. THANK YOUUUU SO SO MUCH FOR THIS. REALLY HELPED ME💖😍

[@Leah4sciMCAT]

Glad I was able to help!

[@AmyStylinson]

This explains so much. Since the ring forms from the back, I think drawing the arrow attacking in that direction would be better but it would look messier

[@Leah4sciMCAT]

Glad I could help!

[@kassandraorr6841]

i've been struggling to understand how to do this and nothing seemed to click. After watching this video I understand this concept so much better. I am extremtly greatful.

[@Leah4sciMCAT]

That makes me so happy to hear!

[@lei1921]

my one and a half hour squeezed into this. Gee, thanks. All lot better.

[@Leah4sciMCAT]

You're welcome!

[@whupwhup2455]

thank you for this.You saved my exam

[@Leah4sciMCAT]

you're welcome! glad to help! :)

[@lorenaviannay4288]

perfect!!!! i was looking for something like it for long time!

[@Leah4sciMCAT]

Glad to help

[@sandanethkim768]

Clear explanation with brilliant tricks ;)) thank you for this amazing video

[@Leah4sciMCAT]

You're very welcome!

[@JoanneGreco]

Thanks for the great explanation and breakdown.

[@Leah4sciMCAT]

Joanne Greco thank you

[@shahlaghazal5476]

I'm from India and u helped me a lot.thanks chemistry qeen 🤗🤗

[@Leah4sciMCAT]

You're very welcome!

[@shambhavichaturvedi4724]

Such a wonderful explanation!

[@Leah4sciMCAT]

Glad you enjoyed it

[@hayanium]

Thank you so much. I kept getting my hw wrong when I just read the book then you helped me a lot! thanks!

[@Leah4sciMCAT]

You are welcome! Glad I could help!

[@makennaadkison6217]

This was such a great explanation!

[@Leah4sciMCAT]

So glad it helped you!

[@zhiarempola]

i really like the way you see it. it's fun.

[@Leah4sciMCAT]

+Zhia Rempola Thank you, hope it helps

[@RakeshKumar-cc4qo]

Thanks it was so helpful on the eleventh hour. Clear explanations for a complex topic.🤗

[@Leah4sciMCAT]

You're very welcome!

[@zarifmuhtasim]

your tricks are life savers

[@Leah4sciMCAT]

You're very welcome!

[@Hanna-to2wc]

Thank you for this. It helped a lot, simply and quickly !

[@Leah4sciMCAT]

You're welcome! Glad it helped

[@ipuffyface]

thank you so much Leah....ur an angel

[@Leah4sciMCAT]

Aww thanks! And you're so welcome!

[@Shan-sg7mm]

You made it easy to understand. Thank you very much 🙏🙏🙏

[@Leah4sciMCAT]

You are welcome!

[@erin2704]

Amazing explanation! Thank you ❤

[@Leah4sciMCAT]

You're so welcome! Glad you liked it.

[@SyskaRibalt]

I have an exam on Thursday and I wasn't able to draw fisher to haworth. Thanks a lot !

[@Leah4sciMCAT]

+Marion Rebeaud awesome! glad to help! how was your exam?

[@kadbio2610]

thanks !!! this is the most simple and clear explanation

[@Leah4sciMCAT]

You're very welcome! Glad it helped!

[@agent475816]

Is it safe to say that if it's a D-sugar, the CH2OH group points up and if it's a L-sugar, it points down?

[@NishantGogna]

Yes, that's what I gathered too.

[@dpsthastha2242]

agent475816 hmm D&L configuration is based on the postion of C-5 ( -OH )... if OH if right it called D form and if OH is left it is called L form...but alpha and beta configuration is based on the postion of C1 with respect to postion of C6 in cyclic structure..if c1&c6 OH are in same side it is call beta form and c1 &c6 OH are in different side it is called alpha form

[@agent475816]

Yea, but I'm saying in the ring form, if the CH2OH group is pointing up, it's always a D-sugar and if it's down, it's a L-sugar. It doesn't matter whether it's alpha or beta.

[@lenaalsaleem3769]

Hmmm it's easier to determine the CH2OH whether it's up or down depending on the D and L configuration. 👍🏼👍🏼👍🏼 Thanks for mentioning that, I will depend on it. I see it's right.

[@Leah4sciMCAT]

That is correct!

[@roadallowance]

The definition of an alpha anomer is that in the Fisher projection the OH at C1 is on the same side as the OH that defines the structure as D or L. The beta anomer is the opposite - in any sugar. This is when the ring is drawn to continue to the backbone up from C1. Also, the name Haworth is pronounced with a short a sound (not Hayworth).

[@Leah4sciMCAT]

Thanks for the feedback

[@Foxign_]

10:40 is the CH20H equatorial? also in CH2OH is the H/OH there considered if asking how many H/OH are present

[@Leah4sciMCAT]

Yes, the CH2OH is equatorial in that drawing. You would definitely count that as an alcohol group in the structure.

[@NANINANIKIDS]

Wow! fascinating!

[@Leah4sciMCAT]

Glad you liked it!

[@NishantGogna]

Wow, thank you! This is fantastic! Take my subscription!

[@Leah4sciMCAT]

You're welcome and thanks for the sub!

[@shahdm.7698]

This vid is really helpful to understand biochem thanks!

[@Leah4sciMCAT]

You're very welcome!

[@Icybubbles945]

Thank u thank u thank u so much for this video!! I had so much trouble understanding Fischer to Haworth and now I finally understand!! This is an amazing video! Will def recommend!

[@Leah4sciMCAT]

You're very very very welcome! Glad I could help

[@hannahwoodruff4864]

This was so helpful! One question: If the carbons are numbered by priority for the D glucose molecule, how come for the D furanose carbon 2 is doubled bonded to an oxygen? Wouldn't that be highest priority?

[@Leah4sciMCAT]

The chain is numbered from the direction of the carbonyl, however the end of the chain still gets a number 1 making the carbonyl the lowest possible number on the chain (in this case #2 rather than #5)

[@rahulkanojiya8963]

You make all the things too easy...and explains in very impressive manner....☺️ With cutest voice...marry me

[@Leah4sciMCAT]

Thank you for your kind words, but how about we keep our relationship professional?

[@lenaalsaleem3769]

Useful almost 15 minutes 👍🏼 I understood it.

[@Leah4sciMCAT]

Glad you liked it!

[@toyositimilehingeorge4680]

Thank you for this great explanation.

[@Leah4sciMCAT]

You're very welcome!

[@DerOerdl]

Thank you very much for your explanation! :D The organic chemistry exam on Saturday will be rocked (y)

[@Leah4sciMCAT]

How did your exam turn out?

[@DerOerdl]

Leah4sciMCAT Quite good acutally, I passed :D Heading towards biological chemistry next semestre (y)

[@Leah4sciMCAT]

congratulations!

[@shalis2000]

how do you know that the OH on 5 is the one that attacks? Your videos are soo helpful. Thank you!

[@Leah4sciMCAT]

I'm so glad to hear that my videos are helping you! We know that 6-membered rings are the MOST stable kind of ring structures and have minimal bond strain. By having the OH on carbon 5 attack, we form a stable, 6-membered ring.

[@deannalum5535]

i found this so useful thank you so much !! ^^

[@Leah4sciMCAT]

+Deanna Lum glad to help

[@abhijeetbaliga5198]

How to recognize if a compound is D or L by looking at the Haworth projection?

[@lenaalsaleem3769]

abhijeet baliga If the CH2OH is up then it's a D-sugar, if it's down it will be a L-sugar. But most sugars in nature are D-sugars.

[@progress360infra5]

thanks to both of you

[@alaataha1558]

Note that when when assigning alpha or beta it dependent on the CH2OH too, meaning if the hydroxyl on the anomeric carbon points in the same direction as the CH2OH its a beta (since most sugars are D we kind off generalize and say up is beta but just watch out for that.)

[@Leah4sciMCAT]

Take a look at what happens to that specific carbon and OH group when converting from Fischer to a ring. Notice that on D the CH2OH points up, while on L it points down

[@incredibleizu4]

Fantastic video, thanks a lot 😊👍🏼

[@Leah4sciMCAT]

Glad you liked it!

[@loneuchiha9181]

Thank you ma'am ...your video helped me alot

[@Leah4sciMCAT]

I'm glad you found the video helpful?

[@koondoog4282]

Thank you Leah

[@Leah4sciMCAT]

You're welcome

[@hoanbuikim3770]

Thank you so so much. It's very easy to understand.

[@Leah4sciMCAT]

Glad to have helped! :)

[@enssiehbagherzadeh1857]

this video really saved me thanks a lot

[@Leah4sciMCAT]

You're welcome! Glad it helped!

[@swabridawuda9991]

thumps up, perfect explanations, keep up with the good work

[@Leah4sciMCAT]

Thanks a lot, glad it was helpful!

[@TheSlenderMorris]

Awesome video and great website quizzes! PLEASE add solutions to your quizzes so I can confirm I've got it!

[@Leah4sciMCAT]

I'm sorry about that, I will be uploading it shortly

[@oumaaima1613]

im so thankful, really really thank u 💜 u saved my life

[@Leah4sciMCAT]

You're very welcome!

[@sarahbelaid7704]

7:09 if ch2oh is the opposite of oh (the fifth carbone )we can distinguish between the D and the L in the cyclic form ? if the ch2oh is up so it is the serie D ?

[@Leah4sciMCAT]

Yes, D will have the CH2OH up and L will show it down

[@kareemapbio7332]

Excellent explanation thank you

[@Leah4sciMCAT]

You're very welcome!

[@CandanceIsMyName]

thank you, thank you, thank you!! the ring diagrams were so confusing!

[@Leah4sciMCAT]

So happy to help!

[@sagittariusmuhammad]

This is so helpful. Thanks 😊

[@Leah4sciMCAT]

You're very welcome

[@nilazazai5554]

Dear Leah can you please explain the chair conformation for glucose?

[@Leah4sciMCAT]

Explain in what way? Stability, how to draw or something else?

[@niamanadan1164]

You are beyond description,,, thank you so much

[@Leah4sciMCAT]

You are very welcome!

[@wastiayesha813]

Thank you so much 💓💓💓

[@Leah4sciMCAT]

You're welcome 😊

[@wileygillam1007]

So helpful. Thank you

[@Leah4sciMCAT]

You're so welcome!

[@savvasavraam8670]

I'm a student of Medicine and i love to teach others, especially chemistry. What do you suggest? I think by teaching others at something you are good at you become even better yourself.

[@Leah4sciMCAT]

Absolutely! To be able to really teach any topic, you have to understand it at a high level. So if teaching is your passion, go for it! Thanks so much for watching and commenting!

[@yoyoyeahyeah7995]

So with six membered ring, we can convert a linear projection, into haworth projection and then into chair conformation. But if we get given a five membered ring like the one in the video, we can convert it into haworth projection but can we convert it into Chair Conformation????

[@Leah4sciMCAT]

+Alisha Negi chairs are 6-membered by definition

[@yoyoyeahyeah7995]

+Leah4sciMCAT thank you leah. I have just recently discovered ur channel 3 days ago and fair to say I have already watched 15 videos. U r a god amongst men. never thought I would smile while doing organic chemistry.

[@yoyoyeahyeah7995]

+Leah4sciMCAT so I was just wandering is there any weird way in which we could convert 5 membered into chair conformation or no.

[@Leah4sciMCAT]

+Alisha Negi you're more likely to get an envelope conformation

[@yoyoyeahyeah7995]

Thank you leah

[@yellowangrydiamond9341]

you saved my life

[@Leah4sciMCAT]

Hopefully not literally ;) but glad I could help!

[@davidizquierdogomez]

great video....pitty that there is not chair configuration of fructose. On the other hand, what's more stable in terms of chair configuration, the alpha or the beta D-glucose? thank you very much.

[@Leah4sciMCAT]

You tell ME based on what I show you here :) What do you think?

[@chemistrytoday6670]

very clear explanation ...

[@Leah4sciMCAT]

Glad you like it!

[@christinemontaril4366]

hi i'm tin from the Philippines i'm a teacher thank you so much

[@Leah4sciMCAT]

You're welcome!

[@janfayeebojo9718]

Thank you miss!

[@Leah4sciMCAT]

You're welcome!

[@Tudaga]

Thank you so much you the best teacher 💜

[@Leah4sciMCAT]

You're very welcome!

[@popollinei1977]

thank you so much your video was very helpful

[@Leah4sciMCAT]

You're very welcome

[@maymounahigazy9874]

Thanks 🌸

[@Leah4sciMCAT]

You're welcome! :)

[@progress360infra5]

thanks

[@Leah4sciMCAT]

You're very welcome!

[@yusufhasan1794]

This is a smart work

[@Leah4sciMCAT]

+yusuf hasan thanks

[@basvou1787]

Thank you very much , nice work you explained it perfect!

[@Leah4sciMCAT]

You're welcome! :)

[@sinwentian3711]

Leah may I know do U have other videos that describe the reaction of carbohydrate ?

[@Leah4sciMCAT]

All of my videos can be found on my channel page: leah4sci.com/mcatyoutube

[@safaa1515]

Thank you for your wonderful explanation ❤❤ I just wonder if the furan Take the shape of boat and chair or not ?! 🤔

[@Leah4sciMCAT]

You're very welcome! Furan is a five-membered ring, and both a boat and chair are six-membered ring conformations. It will assume neither of these conformations because it is not large enough to do so.

[@safaa1515]

@@Leah4sciMCAT I get it thanks 😊

[@lihuic]

I am a working mom of 2 kids preparing for MCATs in June. What would I do without your videos and your encouraging email? :)

[@Leah4sciMCAT]

So glad to have been part of your journey! Did you take the test already or is it still coming up?

[@lihuic]

Leah4sciMCAT my test date is 30June. Currently at phase 3 of preparations. Followed all your advice, motivational emails. Practising with the section tests, (full lengths once a week) and watching your videos and PBS crash course videos in between. Thanks for all the help Leah!

[@Leah4sciMCAT]

Hope you got through it all and through med school by this point

[@manassehakshay9449]

Can we draw Beta-L-Fructose and Alfa-L-Fructose??

[@Leah4sciMCAT]

+Manasseh Akshay sure can

[@manassehakshay9449]

O.K. thanks ur video was very helpfull.

[@agdoombagdoom8540]

Mam do you have a playlist for carbohydrates and stereochemistry

[@Leah4sciMCAT]

I have one for stereochemistry: leah4sci.com/chirality-stereochemistry-enantiomers-diastereomers-r-s-organic-chemistry-tutorial-series/

[@hadeerrashad5486]

Thank you so much !!!

[@Leah4sciMCAT]

you are very much welcome! :)

[@EboniseStBrice]

Hi Leah ! In the last example is it alpha or beta and how do you determine that?

[@Leah4sciMCAT]

Great question! In the last example, the groups coming off of carbon 2 are drawn with “squiggly” lines because the direction in which they point determines whether it is an alpha or beta position. If the OH group has a downwards projection, it is defined as alpha. If the OH group has an upwards projection, it is defined as beta.

[@alexschoengen1362]

Thank you!

[@Leah4sciMCAT]

You're so welcome!