Serotonin vs. Dopamine - 7 Key Differences Between Pleasure and Happiness

Serotonin vs. dopamine explained by Dr. Robert Lustig author of "The Hacking of the American Mind: The Science Behind the Corporate Takeover of Our Bodies and Brains".
He explains the 7 key differences between pleasure and happiness and discusses the basic brain mechanisms behind various addictive products that are hacking our reward centers.
For the full podcast episode, visit: www.fitmind.com/podcast.
Check out the FitMind neuroscience-based meditation app with 50+ methods, some specifically aimed to boost serotonin levels in the brain: fitmind.app.link/YT4.
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[@RuptureOng]

"The more pleasure you seek, the more unhappy you get" this really inspired me to stop my addictions. May everybody be free of their addictions Amen

[@bunk95]

Addiction is fiction. How are you going to stop doing fictional things?

[@user-uq3ez7qe3x]

Light went on! Invaluable information..... Wow!

[@gilbertosbfilho]

I had the same insight listening to that and thinking the same as you. This shows how powerful is this statement .

[@Vt12365]

Pleasure is also a more intense than happiness. Pleasure is fun. Happiness isn’t

[@beautifulworld6163]

Amen was not necessary bro

[@nishasankaran]

‘The more pleasure you seek, the unhappier you get.’ Amazing. This Basically summed up my entire addiction/ mental health journey.

[@justinzaff]

But what does that translate to .... never do anything to feel amazing , energized, super stimulated?? So we are meant to just stay at a mediocre baseline level without highs and lows ?

[@mikahist4155]

I came to an age (30+) when everything that gave me high pleasures become highly draining.. and i get warm and lasting happiness from the simple fact that i love my health and that i take care of it. Its so constant.

[@jerry-mind-sky]

Well said. Thx.:)

[@noone6953]

@@justinzaff you will understand when you get older

[@jacobcampos2407]

I’ve come to this conclusion too. I just began this video but I heard Alex Hubbard I think who always talks about dopamine having an equally and high and low level like opposite reactions and I thought hmm so the happier we are the sadder we get? That kinda sucks but then I thought about all the stuff me and many other ppl do which is always chase this dopamine over many things nowadays besides drug and alcohol like social media, video games, and many other things like nobody is ever satisfied we’re always sad because we all try to make ourselves temporarily happy for a short time because we think it has no bad annotations??? What do you think. So he said guard your dopamine cause the higher you get like drugs the harder you fall

[@almadeleona]

This is the most important video I've ever watched on the internet. Ever.

[@greatestofalltime4125]

Psilocybin containing mushrooms save my life. They drastically reduced my benzodiazepine withdrawal allowing me to quite illicit pill addiction after three years of heavy daily use before it would had became medically dangerous to quit

[@alpha-tj6jt]

Psychedelic is the answer to most severe anxiety and depression. The use of magic mushrooms completely helps one get over depression and makes you feel like yourself.

[@Alexawhite199]

Malachi_trippp is your guy

[@jessicamuyres4444]

I can honestly say psychedelics experience was probably one of the most profound and beautiful collection of moments I have ever had

[@JuicyLife3]

Certainly, he’s an exceptional mycologist, and i highly recommend his expertise.

[@alpha-tj6jt]

​@@Alexawhite199 is he on insta or what!?

[@saizen4209]

This is the prime example of what should be taught to young adults and teenagers instead of some other useless part of the current education system.

[@BeachBoi1000]

You need to compare with an uneducated with an educated person.

[@ChrrolloDI]

To be fair, he calls dopamine "pleasure" when it's already long been considered the "motivation" molecule. He's right for the most part though.

[@aqibafridi2152]

Who Can I treat this weakness stomach constipation Also give me Answer please Here thanks Alot

[@akashdeepsingh9256]

@@aqibafridi2152 it is bcoz you don't feel good most of the time So running and exercise are good to keep anxiety stress down Running exercise sprinting cardio And meditation

[@gigagoatt]

That and Introversion Vs. Extroversion so some kids can get Homeschooled and not traumatized!! 😇😇😇😇😇😇😇

[@atim99100]

This video deserves a million likes, no one has explained this difference so well.

[@jaru003]

Exactly!

[@masterm8174]

You are absolutely and utterly right.

[@VisionClearly]

I agree!

[@josethegameplaya7775]

Damn right. It's the most underrated greatest piece of advice that I have ever heard. This advice has helped me tremendously, personally.

[@ariaebrahimi3629]

Yes

[@offensive-brat]

I've watched over 100 videos about serotonin and dopamine, about detoxification and intoxicants, but no one ever explained things in such a nice manner. Someone said there's something about low quality videos, that they provide high quality content. Thanks.

[@suvikhyasiingh6073]

Literally correct 💯

[@offensive-brat]

@@suvikhyasiingh6073 nice playlist you got there

[@bunk95]

Do you think this video is non-fiction (not a marketable non-fiction)?

[@jessecole1011]

Try using punctuation.

[@Samantha19658]

As a former vice-principal, you my friend should be teaching in all schools workshops on this !!!!!! To parents and students!!!

[@Nirazen]

7 differences between dopamine (pleasure) and serotonin (happiness). 1. Pleasure is short term like a meal, happiness is long term like a lifetime. 2. Pleasure is visceral you feel it in your body, Happiness is ethereal you feel it above the neck. 3. Pleasure is taking, like from the casino, happiness is giving like habitat for humanity. 4. Pleasure is achieved alone like eating a chocolate cake, Happiness is achieved in social group like in birthday party. 5. Pleasure is achievable with substances like cocaine, heroine, nicotine, alcohol, sugar, some addictive behaviors. happiness is not achievable with substances. 6. The extremes of pleasure, weather it being substances (cocaine) or behaviors like shopping, gambling, social media, internet, gaming, pornography, foody. In the extreme are addictive. There’s holic after every one of those things shopaholic, alcoholic, sexaholic, chocoholic etc but there’s no such thing as being addictive to too much happiness. 7. Pleasure is dopamine and happiness is serotonins. Two different neurotransmitter, areas of the brain, regulatory pathways, mechanism of actions, drivers. Dopamine is an excitatory neurotransmitter. Neurons like to be excited and tickled but they don’t like to be bludgeoned. Chronic overstimulation of any neuron in the body leads to neuronal cell death. Because neurons are so metabolically active so If you keep it up and keep it up that neurons is basically exhaust and die. Even tho you have lots of dopamine molecules you have fewer receptor which means there’s less chance that any molecules will finds the receptor. What that means in human terms is you need more and more to get less and less. That’s the phenomenon we call it tolerance. Dopamine leads to tolerance. And then when those neurons do starts to die that’s called addiction. Serotonin is other neurotransmitter it’s inhibitory. There’s no such things as overdosing on too much happiness but there’s one thing that downregulates a serotonin that’s dopamine. So the more pleasure you seek the more unhappy you get. Differences is Reward and contentment, pleasure and happiness. So Coca Cola does not give you happiness it gives you pleasure. So don’t chase pleasure (dopamine) it will make you unhappier. Some of the ways to boost your serotonin: Diet, Exercise, Bright light, Supplements, Massage, Mood induction, Manage stress, Sleep deprivation.

[@Seramics]

The most educational n brilliant thing i read all day.

[@biedepeuter5081]

Thanks! You made my homework! Now I can read it. In my little book. Thanks!!!❤

[@samirnarvekar8488]

Adequate sleep is necessary for serotonin.

[@samirnarvekar8488]

@Amber Patoc Serotonin can be raised ( & anxiety/depression can be reduced) by sufficient sleep, exercise, being in sunlight, meditation, recalling positive memories and taking supplements like Magnesium, Vitamin D, tryptophan/5 HTP, Vitamin B complex - B6 is crucial , Threonine / Glycine etc. I had chronic anxiety but I got rid of it just by Magnesium and B complex. ( I had no issue with sleep, exercise & sunlight exposure.)

[@vitaly5209]

Thank you, human!)) There is a special place in paradise for you!))

[@assiedol4228]

When he said pleasure is dopamine and happines is serotonine That made everything clear. Now i understand it better. And the 7 difference was a very good explanation. Thankyou doctor! Very good video!

[@HuntingTarg]

I would dare the boldness to correct: Pleasure _is signalled by_ Dopamine, and satisfaction _is signalled by_ Seratonin. These are biochemical mechanisms that feed into the mind the state that the brain is in. I'm not going to explain that distinction because it rockets straight into the metaphysical and philosophical. I will simply say that molecules are not moods; they are like state-signals.

[@gkranasinghe]

@@origindirewolf fortunately you are wrong 😀

[@trexmidnite]

Dopamine is addiction and serotonin is friends and fam

[@rishav2205]

@@trexmidnite Hell no addiction is when you seek for pleasure frequently for no reason. Nature gives every hormone for specific purpose it's the individuals fault if they abuse it.

[@FrankLooez-el6nv]

THANKS VERY MUCH IT'S VERY HELPFULL TO Know IN DEED SEROTIN BENEFITS SHOULD BE THE MANTRA

[@RealTalk-mq2ug]

“Trauma is personal. It does not disappear if it is not validated. When it is ignored or invalidated the silent screams continue internally heard only by the one held captive. When someone enters the pain and hears the screams healing can begin.” ― Danielle Bernock

[@Nuggiez-cz3eh]

Beautiful, thank you for sharing.

[@dp-kz5cs]

I just had a trauma rear its ugly head with out my knowledge of , I wondered all day what's wrong with me ? Such rage ...it hit me the next day .I apologized , but the damage is still done to those around me , seems unfair to have to put up with my issues when I dont know when it will erupt in a nature of anger ( all the ugliness of trauma) buried deep into my subconscious how do I get it out it's been over 40 yrs dammit !!!

[@DL-fi5cc]

Danielle Burnock is a money making brand, very much like dumbing down a description of anxiety and the fight, flight, freeze response and a 'panic attack' which is neither panic or and attack.

[@davidtagauri2034]

"Chose not to feel harmed and you won't feel harmed. Don't feel harmed, and you haven't been" - Marcus Aurelius.

[@timothyacker8686]

It's a matter of regression to the point of trauma and resetting the Ingram.

[@patriaciasmith3499]

Psilocybin saved my life. I was addicted to heroin for 15 years and after Psilocybin treatment I will be 3 years clean in September. I have zero cravings. This is something that truly needs to be more broadly used in addiction treatment.

[@jeffsmith2447]

Psychedelics saved me from years of uncontrollable depression, anxiety and illicit pill addiction. imagine carrving heavy chains for over a decade and then all of a sudden that burden is gone. Believe it or not in a couple years they'll be all over for treatment of mental health related issues.

[@elizabethwilliams6651]

@Micheal Harris Can dr.sporess send to me in Ny?

[@Jennifer-bw7ku]

Dr.spores is the best, he's been my go to for anything psychedelics.

[@SkyeMpuremagic]

Psilocybin is DANGEROUS and all you did was replace one pleasure seeking mechanism for another.

[@SkyeMpuremagic]

​@Ryan Robinson Do you not get what the point of this video is!? Quit seeking pleasure... Shrooms is not a gateway to happiness. The more pleasure you seek the less happy you will be. WATCH THE VIDEO AGAIN!

[@ranjanmistry5961]

Just how causally this guy explained one of the most important things for human survival, this is in the the top 10 youtube videos of all time.

[@claudelebel49]

"The more pleasure you seek, the more unhappy you get." Science catching up with what mystics have been saying all along. Happiness is your nature. It doesn't need to be sought. It only needs to be realized.

[@muslimahsharing4761]

YES.

[@sharinaross1865]

Your truth is factual.

[@dc9511]

We need to protect this man! 🙏 i can't express myself so incredible!

[@gottagoguylo]

What a fantastic explanation. As a recovered addict, I can totally understand why it’s so fun to help others who suffer from addiction. The lengths a recovered addict will go to share a message of recovery and how it works. Love this video.

[@jimreadey4837]

[@Live_life_with_no_regrets]

you should be proud and happy from recovering from addiction. You are a hero. Unfortunately, my uncle did not realize this and was a victim of instant short-term pleasure. Sadly died three months ago as a result of addiction

[@Mayavee617]

So happy for you! I know how the addiction makes people have a temporary pleasure and make them unhappy all the other time because of one of my friends. I would like to know how you got treated to your condition to help him.

[@njc1903]

I am recovering from compulsive masturbation (dopamine), it’s as cocaine addiction. Got into flatline, and I can get it now what was going on with my body, mind and overall my life. Happy for you! When you get the point it’s easier isn’t it?😊🍀

[@bonganicxaba8416]

@@njc1903 i'm suffering from the same, how can i recover?

[@drew3976]

“There is no such thing as overdosing on too much happiness” *SEROTONIN SYNDROME HAS ENTERED THE CHAT*

[@josethegameplaya7775]

True, but serotonin syndrome is not common.

[@datsuntoyy]

@@josethegameplaya7775 neither is Ebola but it kills just the same. Why risk it by overdoing it?

[@happytehemu]

Yes I wondered about this as well

[@doctorvpc]

But this is iatrogenic

[@muayboran6111]

You cannot develop serotonin syndrome naturally (in most cases) the most common cause is overdosing and misusing ssri medication.

[@NO-kw9cp]

This is so true. I have a dysfunctional prefrontal cortex- I never have thought about future/long term consequences. At age 41 the consequences have started showing up. A lifetime seeking pleasure in the pursuit of happiness led to hatred of myself. Happiness is peace of mind and having people to share your life with. Great video. It’s so sad to me that we have all been duped for so long. They make too much money off of us being sick and unhappy

[@racherlabharadwaj3778]

Hope you have dealt with your consequences!!

[@MisterSmithgrind]

I have this problem as well and started taking an ADHD med about a year ago and it has helped tremendously. I’m less impulsive and can regulate my emotions and focus. Check out Dr. Richard Barkley’s talks. Best of luck!

[@sugarcan1110]

You have ADD wonderful gift just know how to play life with a good strategy

[@sugarcan1110]

@@MisterSmithgrind come off meds and still have the wild NESS but have a step back mentality so you get best of both worlds

[@aventurileluipetre]

actually, a part of the information is false, if the prefrontal cortex doesn't work, you don't "become a reptile", but a mammal. it's wouldn't be like you'll be eating your own babies like reptiles do

[@Banana_Split_Cream_Buns]

As someone who used to abuse methamphetamine, this video tells so many truths with just so few words. Wow! The best time for me to have heard this video was 15 years ago. The second best time for me to have heard this was today. I haven't seen or heard anything this enlightening since when I found Dr Gabor Maté.

[@adityasiddharth6818]

It's like Pleasure is from outside to inside And Happiness is from inside to outside. 🙂 Beautifully explained 👏🌷 Thanks 🙏

[@piaxerofchaos1309]

Yes, also happiness come from things you already have in your life, while pleasure comes from something you have to get more. Pleasure isn't always bad thing, but seeking different kinds of pleasures can easily turn to multiple addictions which can be harmful. Also seeking pleasure can never make you happy, because pleasure is short feeling and happiness is more like state of mind.

[@murtynmahankalin3938]

Anando Brahma.We all are tiny cells of Brahma padardha (cannot be described by 5 elements). So if we calm down we can experience that we are that piece of Ananda ("Bliss" unlimited happiness). Very well explained the content of Upanishads in neurological context).

[@ericpeysar2593]

Mind blown. As an adrenaline junkie w adhd, i always chased the dopamine rush. Now i understand why living life with your hair on fire was “fun” (pleasure) but not “satisfying” (contentment). It also explains why a weekend of dropping waterfalls in a kayak and feeling on top of the world, was often followed by a noticeable little crash of mild gloominess (mild depression) on the ride home or the next day. I figured it was just a hangover. 😂Years ago i remember reading about that little emotional crash after a weekend adventure in an Outdoor magazine. They only went so far as to note the phenomenon but they did not explain the mechanism.

[@cindyrobertson3780]

I am not an adrenaline junkie. I take life day by day now. Thanks to the NAC and Zoloft pills

[@eileencita]

Oh man. I feel you. Adhd is terrible. I have it and discovered it just few years ago, I'm 39 now. Thank God I never developed any drug addictions. However, I had other kinds of addictions. When you have a neurological dysfunction it's not that easy to have a rewarding and functional life. Dopamine and noradrenaline are lacking in a ADHD brain, that's why we are more prone to develop addictions and emotional issues. Plus dopamine is not only related to pleasure, but also to learning, memorizing, emotional regulation, generating prolactine during pregnancy, etc.

[@oceanelf2512]

Wow! Your comment explains what happened to me in 2010 with the Winter Olympics. It was so hyped up, and my family and I were all really into it. Couldn't get enough coverage, it was a two-weak high. But the Monday after the closing, I was near tears all day. It was even worse than the downer after Christmas. Because now the news would be going back to BS politics and depressing stories about shootings, stabbings, molestation etc. And people would go back to talking about stupid so-called reality TV again. Thanks for helping me to finally make sense of my post olympic coverage crash.

[@activistwitch]

This suddenly explains why they all say meditation helps being more grounded and sharp: because doing nothing and have no stimuli for 10 minutes already let the neurons chill from the dopamine. Thank you!

[@muhammad7205]

I wish I was taught this in my formative years. Schools should teach this to teens in highschool.

[@Highonlife_]

No one has ever explained the difference in such a simple way like he did, absolutely very easy to understand and also now it's easy to differentiate whether what I'm doing is a temporary dopamine kick or a serotonin happiness!

[@yourlocalsadboi6299]

I felt so attacked when he said, "Its 5 oclock somewhere" Edit: Idk how I ended up here, but I loved the video. They way he speaks is actually sooo nice. Not to mention how well he communicated this information. This isn't easy to explain 😅 Not to mention the absolute criticality of the topic. COVID messed up sooo many of our brains due to stress and isolation.

[@danielloacker5864]

As someone who's recovered from many different kinds of addiction, i approve this message. Spread the word

[@working9990-hafiz-k]

SUMMARY: Pleasure is dopamine (short-lived, addictive, repetitive) and happiness is serotonin (long-lasting, fulfilling and peaceful) ******************************* Dopamine is exciting; it excites the nervous system. If you repeatedly and intensely excite a neuron (or a neural pathway), the neuron / pathway will get exhausted, and it will die. So, to save it from death, it decreases the number of dopamine receptors on it, so that it does not die. Therefore, you have to give more dopamine to feel the same pleasure by getting more of that drug. This is called "tolerance." But when you still don't stop, the neural pathway actually srats to die off. This is called addiction. Hence, do remember this chain: Drug => dopamine => short-term pleasure via neural excitement => repeated over time => dopamine receptors decreased => "tolerance" developed for the drug => repeated even more frequently => pathway dies => addiction ********************************* Serotonin on the other hand does not increase excitement, rather it decreases it. Hence, we don't down-regulate the receptor of dopamine to prevent from excitement. Therefore, no tolerance or let alone addiction is developed. ******************************** But here comes the twist: there is actually one thing that down-regulates the serotonin receptor. Guess what? Dopamine! What does that mean? The more short-term, quick pleasure you seek, the more unhappy you will be in the long-term. The more dissatisfied and less peaceful you are going to be.

[@ericamacintoshshe-her4767]

This is fabulous. I am a Biology teacher and I was looking for a way to approach neurochemicals and this was perfect. I learned so much myself and I am excited to share this video and underlining concepts with my students.

[@DeAngelo77]

Drop the pronouns

[@HH-gv8mx]

And which of those two chemicals does running release more of? Dopamine? Or serotonin?

[@HH-gv8mx]

@robertcross7571 thank you for the psychology refresher course. You are so smart! ❤👍🏃‍♀

[@RapidHealthYT]

love this so much. great info

[@111orca]

Please please I need to know more about this please can you possibly refer videos because I have severe deslacsia I couldn't understand what's that cortzol thingy I asked many doctors about this video and imagine no buddy have clue.

[@tristanstahl2549]

Wow this really saved me from a period of depression I’ve been in. It’s funny because I was actually thinking that I could be feeling this way because of how much I’ve been stimulating the brain with things lately

[@FitMindMeditation]

Awesome - so happy to hear it!

[@jacobcampos2407]

Exactly is so easy nowadays to get everything you want at the tip of your fingertips so you’ve got to be extra careful to protect your dopamine!😊

[@Mendoxs_]

yeah I was think about it recently. How the day I spent listening to music literally all day made me feel so drained and tired. I didn't want to listen to any more music but I also didn't want it to be silent, it was very frustrating.

[@blackmewtwo3569]

After watching just 5 minutes of this video I realized how much I need to start going outside more often even just to go outside 😂

[@marknesser9602]

Thank you Dr Lustig! Finally someone explains the importance of Happiness over Pleasure and Serotonin over Dopamine in such a concise and beneficial way!

[@dianakastner7509]

This is a really nice take on these neurotransmitters, but it's not as simple as he explained. He made it sound as though dopamine is a villain, and serotonin is the true happy-maker. What he forgot to mention is that serotonin, being the inhibitory neurotransmitter that it is, is also responsible for heightened fear during an aversive stimulus and for default passivity during prolonged inescapable aversive stimuli (aka learned helplessness). What he also didn't include is how the endogenous opioid system as well as oxytocin play a role in all of this. Then, there is the aspect of the location of receptors, which also affects the function of neurotransmitters. Again, while this is really nicely done and explained, I wish he would have limited himself to talking about excitatory and inhibitory neurons rather than specific neurotransmitters. Furthermore, through modern neuroscience, we now know that there is no such thing as a reward center; and dopamine isn't about reward but about motivation to pursue a reward, it's about anticipation of something beneficial, it's about expectancy ... not abbot the reward itself. Just my 2 cents.

[@the_real_espada]

Thanks! I was looking for this comment, because I sensed everything seemed too oversimplified in this video. Do you have any sources, like video or articles to read more about this?

[@dianakastner7509]

@Gemmy George as for Serotonin and learned helplessness, I would recommend the latest research article by Maier & Seligman "learned helplessness at 50". I believe that article was released in 2016, but not a hundred percent sure. Other work that is really good is anything by Dr. Jaak Panksepp or Prof. Andrew Huberman. There is sooo much information available online. Glad you asked

[@aurasensor]

Look up GABA and glutamate

[@activistwitch]

thank you so much for this specification, i was literally looking through the comments beyond the "this is so good" to appreciate the wider context.

[@kevinsteel7875]

Maybe not play the emotional music while I'm trying to learn about my brain?

[@deekshaanchan4463]

This video seriously needs more recognition to it .....this is gonna help me so much with my life Thanks alot sir for sharing this information with us ♥️

[@richardteale3217]

Thank you sir ,for a brilliant presentation of these facts. This subject should be taught and explained to children at school and should be regarded as being as important as maths or reading . As humans we are being led to an awful place by the greed of big business . There is addiction everywhere in many diverse forms . People - please spend time with your kids and explain this to them, else the future looks pretty grim. Many thanks again from a seventy year old Englishman . Goodwill to all .

[@sethnemesis]

This music is unnecessary but the information is very valuable

[@nicnic1190]

I'm AuDHD and the music kept my focus

[@basslinepromotions]

​@@nicnic1190thats actually interesting, I learnt something here

[@mariano7382]

@@basslinepromotions it’s crazy i forget that everybody is different in some way

[@pinkhairedfooltarot]

I loved the music and the video! Thank you!

[@justintime1078]

Your comment is unnecessary.

[@PaulDurdle]

I'd love to hear this exact same video, but directed at someone with ADHD, and thus dopamine disregulation. A lot of the explanation of what both serotonin and dopamine do and provide made sense for me in my life, but the behavioural explanations made me wonder if this applies to ADHD brains as well. Oftentimes, neurotypical explanations don't fully apply to neurodivergent people, and that's why a lot of neurodivergent people feel lost, frustrated, and unsure of why the things neurotypicals tell us to do, don't work.

[@romanovmarkelyon1021]

Good point.

[@muslimahsharing4761]

Exactly. This video is in my time line, i click because it's title is interesting, and i'm learning about dopamine lately, and this describe my adhd teen son so much. There's also a lecture by dr Russel Berkley, that said adhd is basically a blindness to the future. 🤯

[@aurasensor]

Try gaba and alpha gpc. He did not mention GABA and glutamate, which is a substantial shortcoming. These two control a lot of brain chemistry.

[@viviennegreenwood8817]

Just sent this to my ADHD son. We both have it. I hope he does not feel despondent or disillusioned.

[@brianh1969]

I have been recently diagnosed with an imbalance of Dopamine and Serotonin, and this this was truly helpful. I need to boost both, however NOW I know the emphasis needs to be on Serotonin. Plus, understanding the effects of cortisole. This last part explains a tailspin I had been after a series of rough life events. Makes so much sense. "The more ya know", right?!!!

[@shimaarageh9360]

This is what continues to impress me, amazingly talented persons who can simply bring a very complicated piece of information in such easy and well described manner. 👏👏

[@Julie-7605]

Too easy. His points were misleading. But the overall message was good. He's equated Serotonin with happiness. He says you can not overdose on too much happiness. But you can die from an overdose of Serotonin, as well as become anxious and depressed. Too much Serotonin is a bad thing, too. Pleasure is not primarily singular. Sports and sex are better when shared. Giving can also give pleasure.

[@HuntingTarg]

"If you can't explain it simply, you don't understand it well enough." -Albert Einstein

[@muslimahsharing4761]

​@fitaddiction 369 well he specialized in neuroendocrinology, what's sad is how you you think you're more knowledgable than him.

[@eternal2670]

Short time pleasure leads to unhappiness Short time Suffering leads to happiness

[@thisissoeasy]

This "talk" was like an unexpected cold shower for me! A real eye-opener - something I will now thoroughly digest and hopefully never forget! Thank you very much!

[@gloriaa3652]

This is the most important video I’ve seen in forever. Everyone needs to see this.

[@homeworkshopengineering]

What a fantastic overview of how this works. It would explain why after getting diagnosed and treated for ADHD I am now seeking less buzz from pleasure and less stress (which I used to cause and thrive on) and now seeking a more stable and content existence.

[@TravisPluss]

Same here

[@HH-gv8mx]

And when you take pills like Adderall, for instance for ADHD it does something to the dopamine and serotonin but I forget what it is since it’s been over 10 years since I took those classes. And when you come off those ADHD meds those chemicals are broken and they are not released anymore so you don’t feel pleasure or happiness

[@homeworkshopengineering]

@@HH-gv8mx This is confusing controlled use at correct dose with abuse.

[@DrSpooglemon]

@@HH-gv8mx People understandably are uncomfortable with the idea of daily amphetamine(Adderall or otherwise) use but for the truly ADHD brain the correct dosage has such a powerful effect on emotional and behavioural regulation and facilitates the avoidance of unhealthy habits and a move towards goal oriented behaviour and self-actualisation. There are two types of dopamine release - tonic and phasic. Phasic release occurs in response to something pleasurable and tonic is the constant hum of dopamine that keeps you moving when there is no direct reward. For people with ADHD maintaining slightly elevated tonic dopamine via stimulant medication does two things - it keeps us active and focused when we are not being immediately rewarded and diminishes the intensity of phasic dopamine release making us less distracted by things that we would otherwise be inclined to fixate on(vis a vis become addicted to). This is where the hyperactivity component comes from. It is the individual attempting to elevate their own dopamine to prevent their brain from just drifting off into day-dreaming. So stimulants paradoxically make someone with ADHD less hyperactive at medicinal doses. Yes there may be some downregulation of post-synaptic receptors and upregulation of pre-synaptic reuptake sites but this will be minimal and is not going to lead to withdrawal symptoms at medicinal doses. People who abuse stimulants on the other hand, whether they have ADHD or not will suffer long term. But the ironic thing about ADHD is that the unmedicated are far more likely to adopt unhealthy habits/addictions - drugs, porn, gambling, social media, etc.

[@HH-gv8mx]

@@DrSpooglemon your comment made a lot of sense and was easy to follow. Thank you for that. I have been on ADHD meds for 20 years. And now have not taken them for over a week because I lost my whole conference I can’t get into the doctor without paying a total of $600 for the doctor visit and then for the prescription. It’s actually cheaper to buy these drugs off the street. Which is sad and says a lot about how badly we need universal healthcare in this country! Because it’s dangerous for someone who’s been on that type of medication for over 20 years to suddenly stop taking it.

[@id6964]

Notes: Pleasure is dopamine, happiness is serotonin. Pleasure is visceral, you feel it in your body. Happiness is ethereal, you feel it above the neck. Dopamine downregulates serotonin, the more pleasure you seek the more unhappy you get.

[@video_kid95]

this blew my mind. As someone who has personally struggled with perscription stimulants and alchohol use , THIS made so much sense as to why I feel the way i do. THANK YOU. truly

[@dojagi1461]

This makes sense so much. Thank you! The world of freedom where we live comes with responsibilities to a happier life. No wonder so many people are depressed.

[@shweta176]

This is an eye opening video..... This proves that being materialistic doesn't make us happier. Thank you sir 😊😊

[@GANESHKUMAR-lu9fz]

dont you wish it must have taught to us way back somewhere in our education system at schools or colleges

[@FitMindMeditation]

NOTE: It's come to our attention that the background music is too loud for some. Please accept our apologies. It's unable to be changed. If you'd like to listen without the background music go to 8:36 in this video of the full conversation with Dr. Lustig: kzbin.info/www/bejne/r3WxkmCXeJuqeKM

[@fortheworld3351]

Glad that I thought of reading the comments before commenting! It is such a brilliant video and I was feeling bad to comment on the bgm. Thank you! Thank you! Much appreciated! ❤️

[@RapidHealthYT]

yes i noticed too! a good balance helps keep the audience retetion!

[@RapidHealthYT]

@@fortheworld3351

[@kevkonk]

I have no problem with the music, but I recently found out that in YT Studio you have the option to change it, mute everything or even remove the music and retain only the speaking part.

[@ronenboyme7414]

This has got to be the most informative and important information ive heard all year

[@nandantavkar]

Neurology + Philosophy - this video is gem 💎.

[@lukastheprussian4465]

There is also that difference in the bible, the difference between love and lust. Lust is the opposite of love. Love satisfies - lust is never satisfied.

[@tiamelancholyjeoncockity]

this is probably one of the best and most useful vids I've come across so far 💗

[@kailahayes1430]

I am grateful to you for sharing your knowledge on this topic. It takes a talented person to explain things to others in the manner that you did. Thank you. God bless.

[@simi1547]

Why hasn't this video attracted a million views already? Pretty clear explanation.

[@southerngrandma4353]

I Agree! I’ve been watching videos for days on serotonin and dopamine and he definitely explains those two things better than anyone

[@josethegameplaya7775]

Couldn't agree more with you!

[@kwninjatrainer1412]

This deserves far more views. Great content thank you

[@zainuba87]

Reminded me of our Pathology Professor who didn’t use any illustrations or power points even then we would sit and listen to his lecture and could actually remember that after the class… I appreciate it 🙏🏽

[@Terryanneserem]

Jeez... this is by far the most detailed explanation on KZbin, of how the brain neurotransmitters work, simple and clear, this guy needs to have over 5M subscribers and views. I hope many people find this.

[@andreyassa7638]

The interaction between dopamine and serotonin is quite intriguing. Thanks for a video explaining complex matter in a comprehensible way! It's mind blowing to get the meaning of it at its full extend.

[@dylanbenson2323]

Man, you just gave me the answers I have been searching for for a long time. Adds that extra perspective to the left brain right brain stuff. Thank you. You got another subscriber.

[@fahadirshad6996]

Knowledge at its best. Its not merely a medical advice but a life lesson in its pure form. I always struggled quiting smoking addiction but never dodged it by psychological reasonings. Today I feel something new, some knowledge working as a medicine. So the power of knowledge and awareness seems to defeat ignorance. Thanks Sir, i dont know your name, I still have to subscribe you. For me, you spoke like an angel. God bless you, wish i could ever see you.

[@lightingmike1242]

This is the first thing that has made sense to me in like 15 years. Thank you!

[@owaisahmad7841]

Beautifully and incredibly effectively explained. Thanks a lot for simplifying these concepts, making it easy to identify the two and most importantly what to strive for in life !

[@fulaahmed9762]

Oh my God , it's amazing how this one video can tell us almost everything we need for today! Thanks 💗

[@SaunaShruti]

Thanks a ton. We need people like u who actually educates teenagers like me. We r mostly told to seek happiness disguised as pleasure. We shall seek happiness as being happiness.

[@Ronlawhouston]

Love Dr. Lustig. He is a giant in the area of public health and works very hard to educate people.

[@emilytorres3415]

This is one of the most amazing educational videos I’ve seen. Wished I was taught this at school.

[@sandyliu6264]

Oh my god, I think the whole world should listen to this! I’m so thankful it came to me and I subscribed to the channel right away. Please continue to educate the addicted world. Thank you from the bottom of my ❤️

[@suvikhyasiingh6073]

I don't know how I got recommended this video but I'm very thankful sir ❤😇 this was a very great video by Fitmind. Out of ur many years of experience you taught us this complex behaviour and action of these neurotransmitters in this single video in very simple manner which cannot be learnt easily by colleges and books 🙏 💯 Hats off Robert sir and I'm glad you gave Fitmind time for this very informative video and great knowledge to us. I wish you'd be my faculty in my college. Once again, thank you so much ❤️ May this KZbin platform stay free for us students for awareness and education 🙏☺️

[@venkatakrishnakanthyellapr6931]

Best lecture i have ever heard in my 43 years of life .Thank you sir ( Dr. Robert Lustig )

[@nishantparmar4614]

Very well explained sir. Such a underrated video, it needs more and more viewership, as u mention happiness is achieved in social groups☝🏻🙌🏻👌🏻

[@YuriMichelato]

I've shared your video about stoicism to so many people. Keep it up man, you're doing something special and extremely valuable!

[@jonathanmeier1918]

Great video! Don’t agree with number five tho. Certain substances, like psilocybin (found in psychedelic mushrooms) affects the brain EXACTLY by mimicking serotonin. That’s why people report a deeper feeling of happiness and connection to the world around them when taking these substances. And that’s why you don’t get addicted to them.

[@FitMindMeditation]

Thanks Yuri :)

[@ashrafaliya]

Gifted indeed at explaining complex things

[@dantarradellas7351]

OMG! Years of reading and learning in a short video. Fantastic. Thank you.

[@Weightlosscoach007]

The simplicity of this presentation makes it EXCELLENT!

[@patrickrehorst6530]

Finally a good video that explains the dopamine -serotonin - cortisol triangle. Also useful introduction about of the difference between pleasure and happiness.

[@praveenvarma9107]

I haven't heard a better explanation. Thank you!

[@beingrational1302]

I can't thank you enough. I have been suffering from problems exactly mentioned in the videos and now I know what's exactly happening biologically and so I can help myself. 🙏🙏

[@NathanHarrison7]

What an amazing, easy to understand, numerical breakdown with practical real life, examples. I wish all learning could be this easy and enjoyable. And I wish, as a visual learner, that somebody could create some type of visualization / whiteboard for this. I Subscribed to the channel so quickly I broke my phone. Haha. Thank you for bringing us contact that can truly change your life.

[@DRJupe1606]

Such a great and detailed explanation. I knew about dopamine and Serotonin but the explanation related to pleasure and happiness is amazing.

[@gofortheblue]

Thank you for explaining this very interesting topic in a simple way so that some of us understand the differences better. Now seeking for how to achieve best balance between the 2

[@RohanIrshad-lq1ue]

This man rocks. he healed me already.

[@SuperSijan]

The best explanation of dopamine & serotonin i have ever watched.

[@Ruaidhri]

Superb video, so much insight in ten minutes!!

[@basal757]

Till this moment, this is one of the best videos about serotonin, dopamine, and their relation to pleasure/happines and the differences between them. Thank you sir very much for sharing your knowledge about this subject. The more I understand myself, the more I have control on my life, and my habits.

[@nmtbc3619]

Obviously I am here because I have questions... when the video started... i didnt expect to learn anything from this video... but you explained it so well... loved the analogies you gave.... made me smile ... thank you for the video and the effort into learning the science so you could also explain it to others.

[@rebeccanascimento8234]

Thsta the best explanation I ever found! Took word to word by heart so my impulses make more sense. Having ADD is sooooo hard because you basically have neuron death so much faster, so you need to reaaaally organize yourself to balance your life out. Microdosing, therapy,weed, family and friends, exercise,good food and spirituality in balance makes life finally feel not only worth living, but both EXCITING and PEACEFUL.

[@wixzam]

Wow. I am definitely a dopamine guy. Not proud of it but it is a fact. I am trying to get out of this loophole but I always fail. I hope I may be able to get myself on track someday. An example I personally experienced about what was mentioned in this video is mental clarity I felt after I quit smoking for a week. I was so happy to see the trees around me. I noticed everyday things around me that I wouldn't normally notice when I got all the quick pleasure episodes from nicotine intake. I strongly suggest people to let go of dopamine activating activities for around a month and see the change for yourself. A month in your whole life isn't much, but you will definitely feel a huge transformation during this experiment. Good day everyone!

[@Tholkaappiyam]

A knowledge essential for life, thanks 🙏🏼

[@ARPalico]

Wow this explanation is superb, its really easy to understand and differentiate between the two.

[@wkndengr]

This is the best breakdown I've heard so far.

[@Annie-wx3kc]

Best explanation of dopamine/ serotonin I‘ve ever seen/heard! Thank you so much! Just listened to this again and wrote down the information- wow, this ist such valuable information!!! Immensely grateful!

[@marcrhoades9548]

I can tell a lot of thought went into this video I greatly appreciate it

[@bogotario]

The biochemical reasons of human condition crystal clear explained in a few minutes. Every thing he is saying rings so true. When we all understand and life consequently, then the world will be a different, better place. Thank you so much!

[@jajlegend]

As an extrovert with mostly introvert friends, and who has experienced addiction, I needed to watch this video ❤

[@datoming]

Thank you for this wonderful video. It has unlocks my understanding of the difference between reward-pleasure versus contentment +happiness with a meaningful link to 2 well-known neurotransmitters. I studied pharmacology but I did not fully comprehend how the 2 transmitters play the roles in addiction, depression, happiness 🤩.

[@user-nr2co5sq9u]

I had no idea about such clear distinction between pleasure and happiness, it never came to my mind that they stem from absolutely different mechanisms. I heard about dopamine and serotonin before but nobody whom I listened to had provided such clear explanation. Thank you, I finally got the point.

[@ryanhumor]

💯

[@Medita617]

What about S. P. Infusion of norepinephrine and it's carbon rings ! What is the combination behind it and carbon rings of serotonin ? Every chemical compound has it's endemic rethum or wave generated according to varying ionization energy when excited , and so it's a matter of short circuit . Mind is , How we react to signals from environment and it's the medium We recoganiz them. So if environment is infused with the unsuitable , then our surroundings would also be confused ? Reply

[@lynncomstock1255]

The dopamine/pleasure/addiction explanation is well done. The serotonin/depression connection needs much more explanation than I see in the video. Benzodiazepines mess with the brain's Serotonin level and may create an iatrogenic addiction with long term usage. (Ask Jordan Peterson)

[@VeronicaMist]

Oh my gosh. This is the best explanation Ive ever heard. I actually understand this now. I didnt know how they interact with cortisol either. Amazing. Now I understand. Thank you so very much.

[@cocosasa235]

Highly informative! The choice of words are absolutely meant for people like me who are not quite familiar with medical jargon. I also love the presenter! Pls do more videos with him again.😊

[@joannesuzieburlison7128]

This is outstanding. I'm trying to share it everywhere. So many of my friends, and myself, live with depression and all we ever hear is 'talk therapy' but I think this is such an important piece, its just pivotable to understanding and treating addiction and depression.

[@bunk95]

Depression is fictional. Do you think and act as if thats untrue? Often?

[@truerosie]

@@bunk95 How can you say that literally after watching this video that explains the neurotransmitters and behaviors involved? You are dreaming. Hundreds of people a year do not commit suicide from a fictional nothing.

[@DJDouglasWarden]

I learn more in this 10 minute video that I have in years and reading and trying to learn about the whole process. this information will definitely help me going forward with my issues. and I can share this and help others too. thank you very much