The SHOCKING Truth About Methylcobalamin for Brain Health

[@PianoPatterns123]

Dr. Osborne you are the best medical health teacher on KZbin.

[@saraa4559]

As usual, what a fantastic presentation Dr Osborne ! How I wished doctors/ GP's ... could watch and learn from you to stop the countless misdiagnoses which, lead to so much misery due to their lack of knowledge and lack of curiosity and problem-solving skills. One thing I wished you had covered is functional B12 deficiency ( dismissed by doctors even neurologists!) where active serum B12 is very high -without supplementation- yet all deficiency symptoms are present. Thank you for being a true doctor in its full and true sense ( docere= to teach) and for being such a caring, decent and honest human being. Blessings to you ❤

[@Magnetar11nova]

Dr Osborne, your videos are the epitome of medical wisdom I've come across, and I've watched thousands!. This is the second video of yours that answers questions I've been seeking and asked so many doctors and specialists for many, many years. Thank you 🙏🕯Truely grateful.

[@TheGenoveva7]

Oh Dr Osborne you are heaven sent! Please stay as helpful as you are. I believe you are surrounded by caring people. God bless.

[@jozette-pierce]

Thanks Doc. You are super.

[@ronroads9830]

Another excellent presentation- thanks Doc!

[@mvdmusicvideostorefreshthe3224]

Excellent, very informative. Thank you very much Dr.

[@frederickwilliams5288]

Good! to see you back Doctor. Osborne 👍🏾👍🏾👍🏾

[@preacherman9018]

Many if us have no insurance. We diagnose and trwat ourselves because the local MDs are higher risk than the conditions. What labs/ test companies provide at home tests?

[@Christian-cp1ks]

Life extension supplement company offers blood test. You have to go to a lab to have blood drawn.

[@preacherman9018]

@@Christian-cp1ks Thank you! 🙂

[@AnitaCorbett]

This was another brilliant presentation ✅✅100% Thank you for the science - which is presented in an easily digestible format 😊

[@Mimifromvienna]

Thank you dear Dr. Osborne🙏🙏

[@LF11111]

Thank you, very interesting🙏🏼

[@thwong3996]

Thank You very much Dr Osborne 🙏🙏🙏

[@jeannevaughn41]

Good show today, thanks

[@jeannevaughn41]

As my wife and myself listening to you we looking at out last blood test as you went along. Big fan

[@jackmatthews9390]

Excellent

[@stephaniekays6517]

Good info Doc..... I've had macrocytosis on loads of tests. Been injecting methylcobalamin 2 x's a week for most of 30 years it helps with my conditions

[@RosaleenD]

I have macrocytosis too but the gps in uk won’t give me injections as my B12 levels ‘aren’t low enough’

[@stephaniekays6517]

@RosaleenD send your doc Dr Osborne's videos & naturopaths functional medicine advice & Dr Myhill too...good luck!

[@janetthompson8429]

Thanks Doc

[@johngoh767]

Dr. Peter Osborne. I am 87 years old. I understand taking Methylcobalamin [B12] of 3,000 mcg [3 mg] daily is too high. May I have your advice, please.

[@gabigabriela2802]

Thank you 🙏😇❣️

[@rebeccagarner2576]

B12 saved my life….

[@godsuno777]

Methylcobalamin gave me terrible anxiety, I had to switch to Cyanocobalamin. And the anxiety went away..........

[@Mo-yj3wf]

There are natural forms, not metyl

[@stevierusso529]

? Top daily inclusive multi Vit. today??

[@NYGuy2000]

Several people cannot deal with methylated B vitamins, for example those who are very slow COMT. They should take hydroxy and adenosyl B12, and folinic acid (not folic acid!). Those get converted to the methylated form in the body, but this takes longer and you will feel better.

[@MA-nm2tv]

I read somewhere that any vitamin with a 'methyl' in it is a synthetic form

[@MsSilver41]

@@NYGuy2000what’s COMT?

[@nadjaserafini661]

What is the difference between cyanocobalamin and methycobalamin ? Isnt the first one, done with cyanide, a poison ? Thank you so much for your interesting presentation.

[@kristiemarsh49]

I have severe Crohns and I can’t absorb vitamins correctly ( I’ve had a bowel resection). My B-12 was so low that I had to have a shot daily for a week, then every week,then once a month. I get cyancobalamin from my doctor, but I know it’s synthetic. I used to have an endocrinologist,but Kaiser is EXTREMELY unhelpful when it comes to checking my levels.😢

[@larrytischler570]

Cyanocobalamin is a very poor form of B12. Get the Methylcobalamine. It is also the injectable form as the Dr tells you here. Another reason is the Cyano- group contains a highly reactive triple bond. My experience is using this type of chemical is that it gloms on to too many things and forms tarlike substances. You may be able to get over the counter methylcobalamine but it may have sucralose in it. That is why I mail order it from Life Extension. I also get benfotiamine B1, and, Pyraidoxal 5' phosphate B6, from them. These are very bio-active forms that work together.

[@larrytischler570]

Take the Methylcobalamine sublingual. It is much more available than swallowing or chewing the tabs. I take two 500mcg tabs two times day and probably should take more, but I am getting improvements in my neuropathy with this dosage.

[@Time_Traveler_Karen]

​@@larrytischler570Where can you find this? I have only found the cyanocobalamin

[@sharonmcdaniel4997]

Yes! even though I am vegan my Kaiser Doc would not test me.😒

[@marylawilson4687]

@kristiemarsh49 You absolutely need to take the Methylcobalamine form and the strongest one you can get. I take 2,000 mcg. Taking the Cyanoconalamin is totally useless because your intrinsic factor in your stomach is not working, hence unable to convert the Cyanoconalamin into the usable form. If you get a high reading for b12 later, it doesn't matter because it's non-toxic and it doesn't last long in the body

[@ilisvlad3134]

How to drain homocystein through transulfuration pathway ? Does it needs any other suppliments then B6 which is on the top level for my blood tests. Very hard to drop bellow 10 the homocystein always stays between 10 -11 even with B9 folate methylated B12 or TMG which makes me feel sick. Please need advice

[@rkcannon]

What's the harm in just trying B12? The under tongue type will absorb. I take it and my blood B12 was off the scale. 5000 or 10000 microg. readily available.

[@margaretsmith9637]

Why do the regular drs and insurance companies only give cyanocobalamin injections? What about MTHFR people. How to convince my Dr to give me methyl cobalamin?

[@rochellefreeland4338]

Methylcobalamin b12 is not expensive.

[@heavychevy4616]

thank u sir

[@StarNumbers]

Classic US medicine: no cure, no cause, but have some.

[@PianoPatterns123]

*OUTLINE OF Vitamin B12 LECTURE* - A Vital Nutrient for Health Introduction Vitamin B12, also known as cobalamin, is a water-soluble vitamin essential for various bodily functions. It plays a crucial role in DNA synthesis, red blood cell formation, neurological health, and energy production. This article explores the importance of Vitamin B12, the impact of its deficiency, and how it can aid in treating specific health conditions. The Role of Vitamin B12 in the Body 1. Energy Production Vitamin B12 is a cofactor in the metabolic pathway that converts methylmalonyl-CoA to succinyl-CoA, an essential step in the production of cellular energy. 2. DNA Synthesis and Cell Replication B12 works with folate to synthesize DNA, a vital process for producing new cells, especially in high-turnover tissues like the gastrointestinal tract and bone marrow. 3. Neurological Function Vitamin B12 is involved in the synthesis of myelin, the protective coating around nerves, and neurotransmitters that support cognitive health. 4. Red Blood Cell Formation B12 ensures proper development of red blood cells. Without it, cells become large (macrocytic anemia) and fail to transport oxygen efficiently. Vitamin B12 Deficiency: Causes and Symptoms Causes: • Dietary Deficiency: Common in vegans and vegetarians. • Malabsorption: Conditions like pernicious anemia, atrophic gastritis, and Crohn’s disease impair B12 absorption. • Increased Demand: Pregnancy and growth spurts require higher B12 intake. Symptoms: • Fatigue, weakness, and shortness of breath. • Neurological symptoms such as memory loss, confusion, and balance issues. • Megaloblastic anemia, characterized by large, immature red blood cells. Clinical Applications of Vitamin B12 Autism Studies indicate that methylcobalamin injections can improve symptoms in children with autism, likely due to enhanced methylation capacity and metabolic support. Multiple Sclerosis (MS) B12 supplementation has shown potential in improving the quality of life for MS patients. In some cases, B12 deficiency mimics MS, making proper diagnosis critical. Amyotrophic Lateral Sclerosis (ALS) High-dose B12 treatments slow functional decline in ALS patients, offering a glimmer of hope in managing this progressive disease. Cardiovascular and Cognitive Health Elevated homocysteine levels, a byproduct of B12 deficiency, are linked to heart disease, stroke, and dementia. Adequate B12 intake reduces these risks. Pregnancy Pregnant women require sufficient B12 to prevent neural tube defects and support rapid fetal growth and development. Testing and Treating Deficiency Testing • Homocysteine and Methylmalonic Acid Levels: Elevated levels indicate B12 deficiency. • Complete Blood Count (CBC): Macrocytosis (large red blood cells) is a hallmark of B12 deficiency. Treatment • Dietary Sources: Meat, fish, dairy, and fortified foods. • Supplements: Oral B12 or sublingual tablets. • Injections: For severe deficiency or malabsorption issues. Preventive Measures 1. Regular Testing: Annual blood tests, including homocysteine and B12 levels. 2. Balanced Diet: Include B12-rich foods, especially for vegetarians and vegans. 3. Awareness During Pregnancy: Pregnant women should monitor B12 levels to ensure fetal health. Conclusion Vitamin B12 is indispensable for overall health and well-being. Its deficiency can mimic and exacerbate various conditions, from cognitive decline to degenerative diseases. By understanding its critical roles and ensuring adequate intake, individuals can prevent long-term health complications and enhance their quality of life.

[@vincentmcclelland5726]

It is said that those with the mthfr genetic snip,cannot process folic acid and should only take methyl folate.i have been much better since doing this plus methylcobolamine..

[@jannlittle4745]

I called every pharmacy in my area for the methylcabalimin and no one had it.. US south.. I can only get the cynacabolimin

[@p.p.8624]

Don’t need to call the pharmacy methylcobalamin. You get it from a health food or supplement store, or even online. should be sublingual lozenges

[@jannlittle4745]

@ I will do that. I’m 68 and have been taking the shots (I give to myself) since I was 40 years old..

[@michelemcneill3652]

Used to be able to get it from Florida.

[@rochellefreeland4338]

Vitacost is a great place to order supplements and food. They ship for free if you spend so much and it is usually shipped to you within 3 days.

[@peterKirchberg]

....No improvements were observed in the parent-rated Aberrant Behavior Checklist (ABC) or Social Responsiveness Scale (SRS)...

[@dalewoodhams8364]

Dearest Dr Osborne I see that you work out, but you need to adjust your neck posture. Have you noticed that your head is in front of your body, the stress in your back is turning you into a hunch back. It’s due to your head forward position from reading and computer screen work, with no regard to your posture. Please fix. Yours Dale.

[@chamberlin1]

Isn't Dr. Osborne a board certified chiropractic physician?

[@dalewoodhams8364]

@ well hopefully he knows someone that can straighten him out, literally 🤣

[@user-kc1ci8jg2d]

My hormone doc gave me methyl b12 injection after i asked. I wish they had methyl folate injection

[@szymonbaranowski8184]

it can cause even worse folate deficiency... paradoxically

[@gif24gt60]

Talk about hydroxy and adensyl. Throw in folinic acid.😮

[@c4caffeen134]

Never heard of these but I sure want to now.

[@tanyawieczorek6603]

​@@c4caffeen134 they're two other forms of B12

[@szymonbaranowski8184]

7:20 wow

[@intrinsicfactor5425]

N-acetylcysteine (NAC) can lower homocysteine levels in the plasma:

[@PianoPatterns123]

20 Test Questions with Answers Based on the Video 1. What is the biochemical role of vitamin B12 in energy production? Answer: Vitamin B12 converts methylmalonyl-CoA to succinyl-CoA, a step essential for cellular energy production. 2. What condition is caused by a lack of B12 in red blood cell formation? Answer: Macrocytic (megaloblastic) anemia, where red blood cells are abnormally large and inefficient at carrying oxygen. 3. Which type of B12 supplementation improved symptoms in children with autism? Answer: Injectable methylcobalamin. 4. What is the folate trap, and how does it relate to B12 deficiency? Answer: The folate trap occurs when folate becomes metabolically inactive due to a lack of B12, leading to symptoms similar to folate deficiency. 5. How does B12 deficiency contribute to neurological damage? Answer: It causes an accumulation of methylmalonic acid, leading to nerve damage and demyelination. 6. What dose of B12 was used in the ALS clinical study? Answer: 50 mg of methylcobalamin via intramuscular injection for 16 weeks. 7. What are the symptoms of a B12 deficiency? Answer: Fatigue, brain fog, balance issues, anemia, and neurological symptoms like numbness and tingling. 8. What is the recommended homocysteine level for cardiovascular health? Answer: Below 9 μmol/L. 9. Which condition can B12 deficiency mimic, often leading to misdiagnosis? Answer: Multiple Sclerosis (MS). 10. Why is vitamin B12 particularly important during pregnancy? Answer: It supports DNA synthesis and neural tube development in the fetus. 11. What type of diet increases the risk of B12 deficiency? Answer: Vegan and vegetarian diets due to the lack of animal-derived B12 sources. 12. What is a simple blood test marker for diagnosing B12 deficiency? Answer: Mean Corpuscular Volume (MCV) greater than 99 fL. 13. Which enzyme helps B12 reduce homocysteine levels in the body? Answer: Methylcobalamin. 14. What are two common autoimmune conditions that impair B12 absorption? Answer: Pernicious anemia and atrophic gastritis. 15. What is one key symptom of elevated homocysteine caused by B12 deficiency? Answer: Increased risk of cardiovascular disease, including atherosclerosis. 16. What is the role of B12 in DNA synthesis? Answer: B12 activates folate, which is necessary for DNA replication. 17. Name one degenerative disease where high-dose B12 showed therapeutic potential. Answer: Amyotrophic Lateral Sclerosis (ALS). 18. What common test is used to measure red blood cell size and count for anemia diagnosis? Answer: Complete Blood Count (CBC). 19. What structural role does B12 play in the formation of red blood cells? Answer: It supports the maturation of red blood cells from stem cells in the bone marrow. 20. How does B12 deficiency affect aging and inflammation? Answer: It leads to methylation problems, increased inflammation, and conditions like “inflammaging,” which accelerates aging.

[@dinosemr8141]

❤️🙏❤️

[@cherylreed4377]

Eat beef 😊

[@hoboonwheels9289]

YES! My daughter in law and granddaughter eat junk all week and better when my son is home weekends as he cooks, she tries not to. My granddaughter is on ADHD meds which make me cringe as I'm sure real food is all she needs.

[@szymonbaranowski8184]

it doesn't have everything