How Skipping Meals Makes You Younger

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Watch the full episode here: • David Sinclair: Reveal...
Dr. David Sinclair explains how skipping meals (fasting) can actually reverse the aging process. He explains the results of some studies done on how timed eating and fasting can lead to a healthier, more younger, you.
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ABOUT THE KNOWLEDGE PROJECT
Like the mentor you’ve always dreamed of having, The Knowledge Project shares timely yet timeless lessons for work and life. Past guests include Naval Ravikant, Daniel Kahneman, Jim Collins, Angela Duckworth, Seth Godin, Melanie Mitchell, & Esther Perel.

[@michaelbraithwaite5875]

I'm 76 and I've been doing a 36-hour fast in the mountains every 2 to 3 weeks for the last 4 years. Physically I do everything I did in my 20's and I've noticed I have more stamina and agility than people in their 50's (which I've noticed e.g.playing singles tennis or climbing mountains).

[@rokanza2293]

That is probably because of your good genetics realistically speaking

[@michaelbraithwaite5875]

@@rokanza2293 I agree genes will play some part, but what makes me think environment and way of life probably play a significant role is that one of my 3 brothers (of similar age) has a similar life-style (including regular fasting) to me and amazes people with his agility and stamina, whereas my other two brothers (with poor diet and no fasting) have fared less well (one started to become decrepit in his late 50's, the other started suffering from osteoporosis and reduced mobility in his 70's). For me the findings of scientists like Sinclair and Longo give it additional plausibility.

[@rokanza2293]

@@michaelbraithwaite5875 Interesting. I am 21 years old, would you say I am too young still to go on this fasting regimen since I can probably grow muscularly and perhaps in height more with relatively large amounts of good food ,calories? AKA wouldnt that be good for people when they are older and in mature years and dont need/want the muscular build ?

[@michaelbraithwaite5875]

​@@rokanza2293 I don't think my fasting regimen would inhibit the development of muscles through weight training. Apparently the day after a fast is the best time to do weight training, which I do to avoid the loss of bone mass (which one of my brothers suffers from)

[@rokanza2293]

@@michaelbraithwaite5875 good to hear. But about height though? I generally think for young people like me it is better to eat a lot of good quality foods to get all the necessary nutrients and then later when in mature age then try fasting here and there

[@georgehughes2143]

I'm 75 I stopped eating completely 7 years ago now . Last week I went to buy some alcohol and the shop keeper asked me for ID . I think this speaks for itself.

[@JM-yf7pl]

🤣🤣🤣

[@uptamistik]

Lol

[@mikec4487]

How could you possibly still be alive if you haven't eaten in 7 years?

[@georgehughes2143]

@@mikec4487 easy

[@R.R.Brahma]

You are 75. How many days were you on fasting 7 years ago?

[@littleo353]

I have experimented routinely with all aspects of fasting for the past five years. Five years ago I had serious issues and had multiple doctors telling me I needed heart surgery and knee surgery. I declined both. Obviously multi-day fasting is great for forming the basis of healing. As Dr. Sinclair said it takes about 3 days of fasting for autophagy to fully kick in. Also note that on that third day there are "massive amounts of stem cells" produced (Dr. Satchin Panda is the source of that info). So as the body is cleaning up stuff it doesn't need, it also produces new cells. I experienced such fasts a number of times. HOWEVER most important, from my experiential vantage point, is my rule #1 now - "NEVER EVER EAT AFTER SUNDOWN." Doing so causes massive inflammation no matter what you have eaten. Dr. Panda speaks of this. That as the sun is setting melatonin is being increased for sleep. The increased melatonin is recognized and the pancreas doesn't release insulin - the nutrient manager. So nutrients in the blood stream cannot be distributed and assimilated throughout the body because there is no insulin to manage that. Thus, you end up with inflammation. So whoever created us made us to eat during the day and that, according to my voluminous reading, is what all cultures did. For example, Roman people in the 1st century AD were reported by a historian then to eat one meal a day around noon. An order of monks ate one meal closer to 3PM. Dr. Sathin Panda was asked by another scientist, Dr. Rhonda Patrick which was better an unhealthy meal during the day or very nutritious food later in the evening. And he said the meal in the day was better because "eating later in the evening turns even nutritious food into junk." We have not only been eating junk food but we've been eating junk food at night. And that's why we are all unhealthy.

[@Grefareal]

great insight, thank you for sharing this

[@DankMemes-xq2xm]

I wonder if this is backed up by any research on people that work graveyard shifts. My hypothesis given what you've said is that nightshift workers should be more overweight on average. I'll have to do some googling.

[@rolexsir938]

These all things r written in.Ayurveda

[@antina8162]

That’s nonsense what you say about not eating after sunset. I’ve been running with 1 meal a day, at night and I can eat what I want and as much as I want. I qualify this by saying I also walk ~25k steps a day. Being “on the edge” by training yourself to live with a slight hunger is exactly where you want to be. I call that “in the zone”

[@dingding4898]

Not eating after sunset is a practice followed by Jainism, look about it

[@LeratoM98]

I've been doing fasting and progressing as I adapt and I feel good! On a 5 day fast now and it's great to see the quick progress.

[@aurorasanchez7922]

Dr David Sinclair is Amazing

[@Keithmurray23]

Thank you for your vital work Dr.

[@tracypatterson7705]

I do intermittent fasting,and workout with weights,I'm shocked how muscular I am on very little food,and very high energy

[@greensombrero3641]

losing body fat brings out muscular definition - great work

[@cheekynpc8267]

How long did it take for u to feel good when starting with fasting? I feel so tired a and foggy

[@luffebassen]

@@cheekynpc8267 This is normal the first few weeks. The body needs to re-learn to mainly use body fat. It has been used to always get sugar/carbs as fuel and so it keeps waiting for you to eat some and when nothing comes, then u becomes sloggy`s. So just keep at it. Try eat more healthy fat in your diet like Olive oil, coconut oil and animal fats from healthy animals. Not animals raised on corn.

[@cheekynpc8267]

@@luffebassen thanks! Yeah it stays quite long and i get collosal headaches. I'll restart with a bigger window

[@luffebassen]

@@cheekynpc8267 Make sure to drink plenty of water. Because the body also detox while fasting and so its important to have enough water to flush things out. Otherwise they just keep flowing around in your body and makes a mess. Not saying this is behind your experience, but its something to pay attention to. But once your body starts adapting to breaking down fats and make ketones to fuel your brain, then you will feel much better and be MUCH sharper in the head. I used to have foggy brain and hard time remembering things. Im MUCH sharper after going Keto and also fasting.

[@hendrixdaemon7419]

I've seen this diet, fasting bandwagon on my siblings, relatives and they look thin but also look drained and older. I'm 44 and still attract younger than me coz they say i'm babyface. My advice, first and most important manage your stress, choose peace of mind, choose people around you that are simple minded or not complicated, make you feel good, laugh and make your forget stress, don't be adulting too much, get back to activities that are fun to you when you we're young, 2nd, for me rock music, or music that makes you enjoy when you were young coz psychologically it makes you feel young again, 3rd balanced exercise. Summary, in short its all in the mind, think like a young guy coz mind is powerful and will follow in your appearance. The earlier you apply this in life before you're 40s the more noticeable compared to your same age. Also, don't follow every scientist youtuber you see coz their studies are not conclusive, they are still in experimental stage and you're one of the experiments and it might not really be true after years of study. For the diet, just balance diet is all you need, don't eat too much, that's it.

[@hendrixdaemon7419]

Also i forgot to add in the diet, i learned this from my client who's already 70 and looks 50s and hair is still looks good. His advice eat eggs everyday. I followed it, only eggs every breakfast, its for the hair and skin.

[@sparksdrinker5650]

Fasting bad for health, rock music good for health. Thanks Dr. Daemon but I think I'll stick with Dr. Sinclair.

[@ckamugi]

You don’t know what you are missing!

[@loristrachan8633]

Wow wee .. look at me! I'm 62 and practise just what you have preached here! X

[@MrLuba6a]

👏 👍 The end was the good news 🥳 I just started to eat in an hour and fast for 23h. I feel like a newborn, easy to move, plenty of energy, today walking 17km, etc...and don't have any hunger...amazing 💪 after some weeks will try 3 days fasting 🙏

[@muhubobulhan6318]

It was normal for me to eat one a day, but I used to eat carbs and sugary food that’s why I never lose weight. Now days it’s easy for me to not to eat carbs and OMAD. Today I skip food so tomorrow will be 48 hours.

[@HappyGirl707]

Yes! I wanted to hear more about "when" is best time to eat.

[@MrLuba6a]

@@HappyGirl707 Any time, but not in the morning. Then I walk 10 km and don't feel right putting something in my stomach and go walking 🤷‍♂

[@joaosoares9591]

Fantastic info

[@mikepeek5655]

Excellent info and great context in a few sentences about the biology of genetics and epigenetics. I believe at this point until more discovery that your gut health determines what you can do relative to other people. There are other things too but the microbiome in the gut has trillions of bacteria , good and bad. That is why there can't be a one shoe fits all approach to food. Yes there are similarities among the population. Then, factor in whole food vs processed. I think a whole real food diet vs the SAD ( standard american diet ) can be the difference in overall health. Again, because of the diversity of our acquired genetics and the present state of our gut bacteria along with any conditions or disease will determine how long we will live. We were not meant to sit inside for long periods. We were meant to eat much less and less often, get sun, eat real whole food, and stress our bodies to continue to adapt. We can all argue what type food to eat even if it's real food and not fake food. Eat real food and listen to your body, fast, exercise, get out doors and try to enjoy life. Turn off the TV. Good luck

[@williamwightman8409]

Skipping breakfast always and skipping dinner sometimes is useful. No breakfast extends the night fast and skipping dinner helps me to sleep. Nothing worse (not really...) than trying to sleep and you are hot and agitated most of the night because your stomach is churning and grinding away on dinner and not letting your heart quiet down. Just as important for sleep are a quiet, dark, and cool bedroom and no alarm to wake to. You are lucky if you have all of those.

[@Fearzero]

Eat at least 3 hours b4 bed. Problem solved.

[@jazmin9454]

@@Fearzero I think you mean "no less* than three hours before bed".

[@Fearzero]

@@jazmin9454 Yup!

[@tigertalks1567]

Actually eating breakfast when you're more insulin sensitive and skipping dinner is much more useful. people think intermittent fasting only means skipping breakfast , when in reality according to our circadian rhythm skipping dinner and finishing all food by about 1:00 p.m. is superior by far.

[@kathleenking47]

We don't need dinner as much. Unless training children or holidays Like Thanksgiving. CHRISTMAS. Easter. 4th of July. Etc Or going out on A date I need to eat in mornings though 😊

[@ChannelJtotheD]

I eat every fruit and vegetable and lots of protein. Though I as much as possible avoid sugar. Eat twice a day. Try to be physically and mentally active. I’m hoping that this lifestyle will help with health and longevity. Want to know when during the day should we eat. As you mentioned Dr Sinclair it’s the time in the day that we eat that matters. Thank you

[@Lp-ze1tg]

I actually tried one meal per day for one week. I really look better and feel better. Will try again this month.

[@kaszapnagypeter]

If you felt better, why did you stop doing it?

[@Lp-ze1tg]

@@kaszapnagypeter I am living with an elderly and she doesn't understand fasting. She thinks it is bad for me

[@bmarie8965]

Don't lie

[@Lp-ze1tg]

@@bmarie8965 Are you living with me?

[@Love-kc6yk]

@@kaszapnagypeter because it's still hard. We all feel better after exercising but how many of us do it consistently?

[@danielfardella1622]

David! We spoke several times when I wrote the MSS "Pillstorm" - you are doing a great service and I'm enjoying your posts. Several years ago I began a new eating schedule where I only have coffee in the morning and a nutrition drink in the afternoon the a small meal for dinner. At 6' I am 178 lbs and still limit breakfast. I believe that between supplements and this diet I am in better shape now at 68 than I was at 55. Keep up the good work! - Dan

[@60-Is-The-New-30]

So, this will make you live to 150? According to Sinclair, fasting extends lifespan by over 30% in mice. Oh, wait, I just remembered - WE ARE NOT MICE!!!!!

[@jz5005]

Awesome laser focused questions!

[@morfsevals4106]

You do a good job helping people👍...Be a part of Encouraging Life Success Day...October 3rd, Encouraging Life Success Day is a day where we all wear green, which represents GOING for our goals and dreams while encouraging others to GO after their goals and dreams as well. October 3rd, Encouraging Life Success Day, wear GREEN 😊

[@tonyggir]

I am 77 and for 4 months I have done 16/8 to 18/6 intermittent fasting along with reduced carbs. My blood sugar levels are now normal instead of pre diabetic

[@yuvaryugam3434]

Awesome! How much carbs in grams do you consume daily? What does your diet look like in general. Eggs, meats?

[@tonyggir]

I don’t count the carbs anymore since i started fasting by skipping breakfast. I try to eat very few carbs at lunch maybe 2-3 crackers. Then at dinner I will eat more. But the fasting lowers your insulin resistance which helps you process the carbs better when you eat them at dinner. I eat a lot of cheese nuts fruits meat tomatoes and avocados at lunch. And normal foods at dinner but I only eat small amounts of bread.

[@gsc512]

Let's complete and review the research.

[@user-cw1rm1hh5s]

It's hard what to believe nowadays because a lot of nutrition experts have also different perspectives. I came to a conclusion that it's not how long you live life it's have you live life to the fullest.

[@mritzs5142]

I’m fasting now 16 or 18 from the day before but now it’s also for economic reasons! It helps my budget to skip a meal or two I’ve never liked breakfast I’m hungry, real hunger about 2-3 PM , so I usually eat around then. later maybe 2 hours later another smaller meal . My favorite is yes. a bowl of 🥣 cereal

[@wmp3346]

Skip the cereal, very processed

[@Fearzero]

Eat steel cut oatmeal with a teaspoon of pure maple syrup, a handful of walnuts and a cup of homemade cashew cream and you can thank me later.

[@IAMBERTLL]

@MRitz S , I usually have 2-3 Tbs of yogurt with 2-3 Tbs cool whip and top off with 1/4 cup fresh or frozen blueberries... I also eat a half banana...yum That keeps me satisfied for 3-4 hrs.

[@IAMBERTLL]

@MRitz S, we shop at Aldi to save Big.

[@garydownes1594]

Cereal is bad.

[@dune7824]

When you eat seems to be important. I also eat in a 2 hour window each day with 22 hour fasts but I found that eating in the morning lead to much better results in terms of weight loss and I sleep better at night. I know other people who prefer to eat a large dinner and feel great.

[@winbalingit8502]

Hot or cold stress is good for longevity. Do menopausal heat flashes count? I have had a thermometer in my mouth and my body temperature did increase.🤔

[@user-cw1rm1hh5s]

Stress is the killer and having a peaceful mind is one of the major components of longevity.

[@markjones2453]

I have noticed when I eat a small breakfast and a small dinner skipping lunch I have way more energy throughout the day a little hungry but way more energy

[@johnnycrowbar6489]

Maybe u should eat less carbs then because this rule is the law. Proper food = energy. Try Keto

[@joeydudester1]

Can someone answer why David mentioned that we 'reduce proteins'?? I don't understand because I assumed that proteins were important building blocks especially in aging. Thank you in advance.

[@Hisloyalservantslistenlove613c]

Regarding wine on the Mediterranean diet, the same benefits are in grapes but without alcohol (which is a drug).

[@justsomeguy1671]

Hmmm I wonder if alcohol in moderation is actually healthy... Like 1 shot per week. Stress kills, if it relieves stress, it may tip the scale who knows...

[@darrelllancaster9554]

I just turned 68 and want my golden years to be golden. Started doing things differently. Point is, the less I eat. The better I feel. Honest. D🌞☯️

[@zayn5548]

Even in Ayurveda (from ancient Hindu) suggests food to be eaten from sunrise to sunset, where your digestive fire is at peaks but also gives you a window for fasting.

[@user-ib9ky2jo9h]

Sinclair>Ayurveda

[@zayn5548]

@@user-ib9ky2jo9h lol, Ayurveda dates back to 2000 years. I am not mocking Sinclair but the research he has done was done by ancient Hindu saints long back. Ayurveda> everyone

[@user-ib9ky2jo9h]

@@zayn5548 Ill take science over pseudoscience any day

[@zayn5548]

@@user-ib9ky2jo9h how ignorant of you to blindly call something which you haven't studied as pseudo science😂

[@user-ib9ky2jo9h]

@@zayn5548 'Ayurvedic medicine is considered pseudoscientific because its premises are not based on science.[4][3] Both the lack of scientific soundness in the theoretical foundations of Ayurveda and the quality of research have been criticized.[4][110][111][112]'

[@tomipontynen5642]

I have been skipping dinner for 4 yrs I do not need any food until breakfast 6 am

[@carolinelewis952]

Is it necessary to get your daily protein in that one meal? I have trouble eating all that food in one or two hours.

[@DH432hrtz]

David is an incredible orator of all things young. Finding him on Rogan was instrumental to my survival nearing 4 yrs. Over a yr and 1/2 I took nmn resveratrol and to a lesser time metformin. I turned 60 this summer and all I can atest is everything David shares on aging is gold. I in general don't trust most of the supplement world mainly because of hawking aspects. Thing is David until his book came out didn't sell anything, in truth you don't need to buy his book he podcasts and routinely gives away his message! I could spend days talking about one of sciences greatest modern thinkers, instead I will say this. If you are intrested in finding an alternative to why you age and how your current understanding isn't working, if you want to feel younger vibrant youthfulness, energetic, healthier! Dr David Sinclair is not a cure he is where you start! Finding your path to youthfulness dosen't have to be difficult its that simple.ask yourself does my current way of living offer you health ? do you have a youthful outlook? Am I having my best life? am I Happy. I've used his suggestions personally and I began to really live in my mid 50s, I have cancer and liver disease and I have more energy now then I've had since I was in my early 20s I still have issues I don't use any form of cancer drug nor do I use drugs (street or legal) the later is why I have liver disease! For me I went from 230 lbs to 138 lbs from disease of liver and skin cancer. I had 2 choices in 2019 change or die a miserable death. You see I came to this Crossroads as a result of many poor decisions. Fasting helped me to the first step, simplification of life choices was step 2 getting out of my head leaving room for change and incoming new information. Less poor choices from food and consumption in general. Allowed me a shot at a new life. This may not help you, that's normal, however my new choices have given me my best life! Fasting, gave me a new choice! I'm fond of this saying especially on the topic of fasting or aging ( it's not what you take - its what you take in ). I wish you all a long and healthy life! Doug 😎

[@vivianerochel3250]

I love your videos Dr Sinclair. I’m 40 years old and I have retinitis pigmentosa (cataract, night blindness and tunnel vision is already going on) and I’m trying fasting as an alternative since there isn’t a cure yet . I’ve been fasting on weekends for about 3 months and I noticed that the cataract on the left eye is getting clean small spots. I saw an interview where you said rats are getting their vision back. I’m going to order the inside track blood test to see if it’s working . Any tips to slow down the RP? Thank you!!!!!!!!

[@transformationcentral7501]

Have a look at Dr Joe Dispenzas meditation technique. In particular moving your energy from your 'survival energy centres' (aka chakras) and moving it up to your cerebellum...then a longer whole body meditation. Even better get to one of his 5 day workshops where you can heal yourself!!!

[@transformationcentral7501]

kzbin.info/www/bejne/qpKXqGVuftGthqc that link may explain HOW it works! Namaste! 🙏

[@fVNzO]

You should probably go ask huberman since he's an actual ophthalmologist i don't think sinclair has any credentials in that field? They will usually respond after a new podcast, and i think there's an email somewhere. You could suggest it for a future episode.

[@luffebassen]

Dr. Berg speak about this too. Fasting will clean up the calciumfication going on in your eyes. It comes from too high blood sugar all the time from what i remember. My eye sight improves too whenever i stick to my fasting routines. I have a left eye problem too.

[@freedom2084]

Thanks. I’m looking into the inside tracker blood test site

[@shadows4271]

I was in a corporate meeting of doctors in my company management structure.The idiot they hired to plan and develop a nutrition plan for the company's clinics to recommend to patients actually suggested 345 grams of carbohydrates and 6 meals a day. I just about lost my marbles and ripped everyone associated with this lunacy a new one. This on top of endorsing highly processed and hydrogenated vegestable oils as a "healthy" option. I really lost it big time and asked everyone involved if they want to heal patients and maintain health or if they want to start killing off our patients. Unbelievable in this day and age with all the new nutritional information and research available.

[@auliaaliyev4759]

As an athlete, the news about eating less protein in general is challenging to accept. We are wired to train hard and eat primarily protein for muscle hypertrophy. I know that Dr. David Sinclair also goes to the gym on weekends so... any thoughts?

[@byronvman]

Yes I agree. I think a good balance for someone who requires a high protein diet would be to incorporate at least one 36 hour fast once a week and sometimes even twice a week.. so a 5.2/ 6.1 approach.

[@susanschroeder3512]

HOW can I fast with Pre-Diabetes does this not mess with blood sugar in a negative way?

[@positivetimeline2023]

I retired, gave up smoking, and started eating all day long. I put on weight rapidly. I was in such good shape a year ago when working.

[@sudhirchandra9790]

Did smoking suppressed your diet

[@Alan-rw3ez]

try eating twice a day between 12 and 6. Only water in between. cut out most sugars.

[@neskowinsmithrock1206]

Not too late to get back in shape.

[@luffebassen]

Start walking every day and keep increasing the distance. Humans were made for walking and running. Walking fast is probably the best thing for the body. Also do some pushups and pullups for the upper body.

[@positivetimeline2023]

@@luffebassen Thank you! I will.

[@aamirsiddiqui1205]

OMAD and skipping carbs is great. Both healthwise and pocketwise.

[@brenosantana1458]

Carbs are cheaper in general and better

[@66gmoney]

Brilliant

[@garydownes1594]

Are you fasting if you take vitamins during the fast?

[@mikepeek5655]

No affect on insulin being raised per Dr Berg among others. Keeping insulin in check by not eating so much is the key. That's why so much insulin resistance.

[@a.d.7922]

somebody mentioned here not to eat after sunset. Well, what do you do when you are in a Northern Europe, it is a winter time and sun goes up at 9am and goes down at 3 pm? It is only 6 hrs of daylight. Are you suggesting not to eat anything after 3 pm during winter time? what about those who live on Alaska and have long period of darkness?

[@MrAlexWtube]

I stop eating at 3pm back here in the US with normal daylight hours. my body digestion stops after that I have found. I lived in Iceland for 2 years and we had same daylight as you....I went to be early...because of the darkness...best sleep of my life. Try your last meal at 3....see how you feel. Your sleep should be great after you get used to it Good luck...let me know

[@HappyGirl707]

I wish I could hear a longer version on this interview. The guest was about to tell us the When is best time to eat based on the study. Does anyone know?

[@umm_rit_]

kzbin.info/www/bejne/iIPHhZmeZsRrbqs

[@BC-justbreathe]

Patricia, in the video description, click on "more" and you'll see a link to the full version of this interview.

[@christopherellis2663]

Unless one's ancestors lived in the Americas, the chances of running from a Smilodon were nil. So, the less time spent in digesting meals, the better the body functions, because it gets to process and distribute the nutrients.

[@Fearzero]

Just eat plants that are properly prepared and you'll have less inflammation. Burnt meat is horrible.

[@badassguy9856]

Fasting is good and beneficial. But if you're taking sunlight and exercising daily and taking good sleep and eating a lot of veggies and drinking lots of water and you are stress free, you will look younger even if you don't fast a single day. The major problem with fasting is that by fasting for a few days, we become deficient of vitamins and minerals

[@marthasubba3083]

Fasting mean we can drink water or without water during fasting ?

[@victoriamc.groggan3777]

Love love love 🤗💕🤗. Dr Sinclair I’m Irish 🇮🇪in Belfast blessings from the Irish fairies 🧚‍♀️🧚‍♀️🧚‍♀️ a bit of fun

[@davidg.johnson7208]

I wonder if dreams at night is also the body creating anxiety in some dreams to create longevity factors. A common dream among many people is the dream of being chased. Many people can control the outcome of the dream but the common theme might be a healthy one your body created? Sound farfetched or can there be something to dreams, in regards to dreams activating sirtuins? P.S. Dogs and cats seem to also have "being chased dreams" as sometimes they start twitching in there sleep!

[@davidg.johnson7208]

Added note: People also seem to be unconsciously drawn to be frightened, but in a way that we know we are still safe. Why watch scary movies? We devoted a day to being scared; Halloween! Incidentally, don't forget to eat "dark" chocolate that day, as it helps to activate your sirtuins! L.O.L.

[@deejayrelapz6903]

i have a question, does the fasting count when your asleep or does it activate better while your awake or even both circumstances apply? what negative effects are there pending on how to fast.

[@marlena4020]

Fasting definitely counts when we are sleeping! Consider the term “breakFAST”-when people wake up and eat after about 8 hours of sleep they are “BREAKing the FAST, hence the term we so naturally say daily-breakfast. Incidentally, it’s “desayuno” in Spanish which also means to “break the fast”. Now I’m wodering how it’s said in other languages….hmmm

[@deejayrelapz6903]

@@marlena4020 good answer insightfully optimistic, think most cultures whatever way we say it derives same meaning.

[@jungleful]

Awesome

[@PLEBEJones]

I fast for 10 years and eat for 2 minutes i feel great

[@marciajazz8864]

Can someone talk About benfotiamine?

[@8888-9]

Well I water fasted 21 days Water melon only 10 days - spasmodic 7 day and 5 day Water Fasting - now going on planned 14 day WF and I feel old Fat in constant pain. So -

[@humannature3916]

To trigger autpphagy, it takes 3 days? Not 16 hours?

[@danthegypsy5871]

Yes.

[@prasadj8676]

David Sinclair is actually 138 years old but looks about 30

[@hadriusreznor3247]

Vampire for sure

[@gabrielapogo]

In my case, I have hyperlaxity in my thumbs (maybe wrists as well) and when I started intermittent fasting, and even fasting in general, my wrist began to hurt a lot. I tried taking magnesium and other supplements but they would not work enough. One day, I just decided not to do intermittent fasting and eat breakfast obligatory and my wrist got better significantly. Mind you, I did my best to get all my nutrients in during my intermittent fasting period. But yeah, I wish there was more info about working out, fasting and just living with such hyperlaxity issues :/ it's pretty depressing

[@OP-lk4tw]

have you tried taking collagen?

[@scienceislove2014]

@@OP-lk4tw eating collagen doesn't mean that you would produce more collagen...

[@OP-lk4tw]

@@scienceislove2014 no shit

[@shiamakhangout4136]

What does one do ,when u fast ,and one’s blood sugar goes down ,then what do u do ???

[@___Anakin.Skywalker]

Just go through it, breathe and try to relax, and perform normal daily routines

[@susanschroeder3512]

@@___Anakin.Skywalker ...............or write your will because if your blood sugar drops too suddenly and too low, you are a goner........

[@___Anakin.Skywalker]

@@susanschroeder3512 RIP

[@beautyshines2124]

skipping meals makes you look younger and saves money from buying more foods.😃

[@getakyoai]

I have a question about this: for someone with acid reflux and history of stomach, intestine or colon problems, is it still good NOT to eat? Because when I don't eat i can feel my stomach acid increasing too much and it hurts. So i can't see how me not eating can be a good thing. If anyone knows, I'd be grateful to hear about it.

[@shazzco1]

Stomach acid can increase by simply drinking water also by just tasting something your stomach gets ready for food thereby producing acid. persevere and your stomach will get used to it

[@maverick792]

Drink water whenever the stomach growls. Increase the fasting duration gradually. Skip breakfast on the first fast, skip breakfast and lunch on the next fast and from then on you can skip all three if you are doing a 36 hour fast.

[@orion9k]

But people experience symptoms like pellagra if they stop eating for too long?

[@christopherellis2663]

Malnutrition results in pellagra How long is "too long"?

[@elizabethk3238]

People react differently to changes in food consumption. Hopefully they're smart enough to figure out what works for them. Stop looking for excuses!

[@jdt8983]

I'm mostly vegan. Didn't catch if that was healthy other than the lack of certain proteins ironically being better for you. Going to switch from beer to red wine. Feel like I can follow a lot of these protocols with a little practice

[@jdt8983]

@Slavery is Freedom, War is Peace yeah I'm sure pure veganism lacks a few nutrients.. I'm occasionally eating farm to fork but after going vegan for a while a lot of meat actually grosses me out now...weird because I used to love it. Will keep my eyes open to some research on the isolate proteins thank you

[@scienceislove2014]

@@jdt8983 that's not true.... You're only missing these - b12 and d3

[@jdt8983]

@@scienceislove2014 thanks for the advice. I started going mostly vegan for the various environmental/animal welfare benefits but now I'm noticing the personal health benefits. Will supplement

[@scienceislove2014]

@@jdt8983 woah you care for the animals...great .. Love you

[@jdt8983]

@@scienceislove2014 yup my cat basically guilt tripped me into veganism. Eve though she's part carnivore. And after the research I won't even kill an insect unless I have too (even they have sentience). Much love back at ya

[@roberthill4307]

I would like to see a discussion between Sinclair and Ted Naiman. Naiman is suggesting a high protein, less fats/carbs diet for better health... hmm. I guess fasting is the middle ground. However Naiman is not a fan of longtime fasts... Would love to see them argue

[@zimskasalamaa]

But what he is saying eating proteins have its good and bad sides, and it seems we can't win either way, unless he finds a way to reduce negative impact of those needed but both harmful and benefitial proteins, so it is not saying don't eat proteins to be healthy as some in these comments suggest, it is just eat enough to cover your protein needs, similar to NAD, it helps our body but if you have cancer it could grow faster So the man doesn't say not eating protein is healthy, but for his study, that is longevity and increasing it, protein consumption has negative impact

[@texastexas4541]

Ancient Indian Swamys fasted indefinitely and all they had was few drops of water and plenty of sunbathing. They lived upto 900 years without any disease or cholesterol issues.

[@2000brisk]

the latest meta-study valter longo was talking about says skipping breakfast INCREASES mortality...

[@givemeliberty700]

I started eating every other day , so 4 times a week , anyone else doing this ? Iv been doing this now for 4 months, I'm feeling pretty good

[@ayishahalsomali7539]

Prophet David fasting

[@tadariusme]

I do and it’s normal to me, usually one meal or two at most then fast 24 to 36 hrs later eat again

[@givemeliberty700]

@@tadariusme same here 😊

[@sleepsmartsmashstress740]

The real paradox is FASTing helps SLOWing of the aging, What a miracle!! I doubt if fasting really works, but I would say that given that we are all gluttons and eating three times the requirement just bringing it down to the reuquired amount and stopping the overloading would go a long way

[@johnnycrowbar6489]

Either eat or dont. Never skip meals

[@bronsonstone725]

I'm seeing everywhere that we should consume 1.2 to 2 grams of protein per kg of body weight. I struggle trying to eat this, in fact I would rather halve this amount or less. This video was very short, I don't understand why. But he mentioned we shouldn't eat too much protein, so what does "shouldn't eat too much protein" translate to?

[@aclassmedicine3306]

The WHO used to recommend 0.4-0.8 grams per kilogram body weight. The recommendations by other authorities recommend much more to keep the food industry content. Traditional diets are closest to the WHO and biochemical recommendations.

[@bronsonstone725]

@@aclassmedicine3306 thank you for your reply, those figures makes better sense to me.

[@DankMemes-xq2xm]

High protein consumption is mainly for building muscle. If you're not going to the gym all the time and trying to maximize your gains, you prob don't need that much protein

[@rasoolzakee3082]

Elijah

[@jasonwelsh417]

You don't mention exercise. Exercise is a huge component, isn't it?

[@hermanharper4594]

Ramadan fasting for 30 days and monday and thursdays everyweek the rest of the year. Been going on for 1400 years

[@yegalrosen7275]

Ramada u eat at night and not during the day....how is that fasting ??

[@maltejohnsson8578]

Is it really early or really late at dr Davis 😏

[@AcidTechnoMan5000]

19:5 IF for 3 years. Feel like SHIT constantly.

[@justsomeguy1671]

Maybe the acid

[@ClarkeScott]

Buddhist monks have been fasting for 2500 years.

[@leo-.-258]

Then we should see if they lived longer than the rest of population. Dont we?

[@TheDaveSharman]

2500 years? Wow! The best I've managed is 3 days.

[@Crimepaysaskapolitician]

Yeah and what do westerners really know about the benefits they get? Primitive humans didn't eat regularly what do scientists really know about the health they had?

[@nofood1]

@@leo-.-258 simple answer, they don't. Fasting: because your body needs a break from all the shit you eat..

[@TheHongkc]

@@TheDaveSharman What he meant is, Buddhist monks don't eat after 12pm noon everyday.

[@smartbart80]

Is botox part of the process?

[@CoderGrammer]

Wait he said reduce protein! Would that reduce muscle mass? Seems counterintuitive to me.

[@Yannnus]

Yes, but... It will give signals to your body that there is something unusual and "wrong" with your body, so your immune system will check you and it will heal things that with proteins won't be possible to see (when you have enough proteins, your immune system will hardly see that something is wrong in your body). So, yes; you will lose your mass a bit, but it will benefit your body. Of course, don't forget to eat healthy and don't skip your juices.

[@CoderGrammer]

@@Yannnus thank u. Makes sense.

[@montycora]

@@Yannnus That makes no sense AT ALL. Yes, reduce protein and don't skip your juices full of fructose and glucose that will super increase your insulin levels. DO not decrease protein. This WILL reduce muscle mass and it won't benefit your body at all. You will reduce muscle mass and when that is done, then it will reduce your bone density and then when you are fully sarcopenic and with fragile bones, you will live a lot longer in hospital. What a stupid advice!

[@Yannnus]

@@montycora On October 3, 2016, the Nobel Prize in Physiology or Medicine was awarded to Yoshinori Ohsumi for “discoveries of the mechanisms for autophagy.” - Please read something about it and maybe you will understand something. I'm not saying it's 100% true, science can be Bowie sword, but for me it makes sense... You will not live all the time on that kind of diet. You will do it once in a month (max).

[@montycora]

@@Yannnus - Autophagy has nothing to do with this! Jason Fung is a great poster boy for fasting and yet he has never told anyone not even ONCE to reduce protein intake. This guy claims the people should reduce protein on a daily basis, not as a result of fasting. I support fasting done in moderation, but if you are fasting you are not gonna be eating anything anyway and it is a different process that eating other stuff and not protein. When you fast, a lot of reactions occur, but when you are simply reducing protein, these reactions are not going to take place because calories are coming in. Dr. Sinclair suggests reducing protein to live and this will reduce muscle mass. And that is the original CoderGrammar is talking about, not fasting.

[@realhi-fihelplarry8047]

You don't have to skip meals, keep them but what is more important is NOT having a 8-14 hour eating window like most people do. 6 hours is scientifically proven to be the best window to eat in, so the body can repair itself. Fasting it just a temporary unsustainable craze which is too extreme and impratical when having to deal with being on the job and being productive.

[@TexterEX]

Accept Jesus Christ before it is too late, REPENT , BELIEVE AND FOLLOW JESUS CHRIST OR YOU WI CERTAINLY GO TO HELL LUKE EVERYONE WHO DOES NOT ACCEPT JESUS CHRIST!!!!!

[@tallowturq]

@@TexterEX no mate, sorry you’re wrong. It’s the great god Kooka Kooka you should be looking to..

[@Isaac5123]

@@TexterEX don't be such a fool. What about all the good people who died before Jesus was born?

[@louiseleite3866]

@@Isaac5123 First, there's no such thing as "good people". Second, they will be judged by their faith in God.

[@Isaac5123]

@@louiseleite3866 so there is no need to believe in Jesus according to you. I agree 👍

[@cornstar1253]

I'm already thin. If I fast I look ill.

[@Andy-yh5ry]

??? at 6:42 David states that it takes 3 days for 'Autophagy' to kick in. Everyone else is saying just 16-18 hours???

[@gstlynx]

40% of beef fat is oleic acid, the fat in olive oil that activates Sirtuins.

[@soilikasanen]

Actually, beef with generously poured oil, ingested with red wine is not healthy.

[@Fearzero]

Beef has trans fats as all ruminant meat does. Very unhealthy along with the oxidized cholesterol you get from those fats.

[@soilikasanen]

@@Fearzero You're right. kasasenkootut.kotisivukone.com/files/kasasenkootut.kotisivukone.com/UK_Biobank_Study_Papier_et_al_2021_Mar_2_Liha_Meat_The_Health.pdf

[@Isaac5123]

@@Fearzero how can grass reared beef have trans fat?

[@mikepeek5655]

@@Fearzero listen to Dr Ken Berry. Ketovore. Dispell myths. If your vegan. Good. But , many people can be very healthy with quality resl transfats.

[@ObeySilence]

Why is Aphex Twin in this video talking about such stuff?

[@shartmann2008]

"I'm a hedonist by nature, and very lazy" :) Thanks for keeping it real.

[@transformationcentral7501]

Does anyone know what David's dad's age is v his biological age??? As well as how many years he has been supplimenting nmn etc...???

[@MitchellMacrae]

His biological age is about 40 he said in another video, his 'actual' age is 52.

[@transformationcentral7501]

@@MitchellMacrae you are right, I saw a recent one where he said 40-42 it fluctuates a bit. Whatever the case at 52, no wrinkles and no Gray hair.... I'm 55 and my son's look older than him

[@MitchellMacrae]

@@transformationcentral7501 Look after yourself Karl. It's never too late to improve your life. :) And you can be an example for your sons to improve theirs.

[@MrBeckenhimself]

You know what skipping meals and fasting also does at least to me? Take away the ability to take a shit every day and erase that and switch it up for being able to take a shit twice a week with some luck. And don't tell me I did it wrong. I didn't. I eat healthy and I tried it for a very long time. The first time for over a year. With ZERO improvement on the taking a shit departement. The second time I tried it for six months, same result.

[@Sharperthanu1]

Skipping meals gives me terrible headaches.

[@lcglefevre]

Carnivore diet needs so much more research. Really is game changing. How Dr Baker can eat nothing but red meat ripped, setting rowing world records and 0 plaque in his arteries surely is amazing. If I was a betting man huge amounts of carnosine and bio available protein and sat fat helps a much bigger role than supplements like nmn ever can

[@Brian-rs4ug]

Generally eat a diet rich in fruits, vegetables,nuts,seeds, and meat twice a week. My fasting window in sixteen to seventeen hours a day. As the result I have dropped seven prescription drugs I was told I would be on for life. Also lost 40 pounds. It takes some trial and error to fine tune what works for you. Although once you do, the fasting becomes relatively easy.

[@60-Is-The-New-30]

YOU STOPPED TAKING MEDICATION because you lost 40 pounds, not because of the so-called magic of fasting. One question - how does this prove that fasting extends lifespan????

[@Brian-rs4ug]

@@60-Is-The-New-30 My eating habits and lifestyle changes enabled me to dropped the prescription drugs. Prescription drugs are rarely necessary if we will take responsibility for what we allow into our bodies and learn to effectively manage stress. The medical Doctors are taught almost nothing about nutrition. During their TEN years of medical training. The typical house wife knows more about nutrition than most medical doctors.

[@60-Is-The-New-30]

@@Brian-rs4ug Congrats on your achievements. Just remember, to keep the discipline with maintaining healthy weight.

[@Fernandez218]

no one would have a problem dying at 96 if when you were 21 everything you had at that age, stayed that way, until 96. it's all the problems along the way that make life miserable and not worth it.

[@internalinjectiontrulyhere770]

I know already cuz was how it is for sum people

[@tealeh2]

don't eat bread and drink coffee especially in the AM..eat fruits drink water

[@Gorlung]

humans are not mice

[@blengi]

interesting that People who are overweight, but not obese, actually lived longer than people whose weight was considered normal, based on body mass index (BMI). How does that correlate with skipping meals as it would be indicative of the opposite surely?

[@Isaac5123]

Having a 6 hr eating window like I do is fantastic. I never get ill no colds or flu. Had covid but no symptoms although I am about ten kilos overweight

[@ettoresabella8484]

Do you use botox? You don't frown at all

[@TexterEX]

he look like vampire, he sounds older but look younger then he should

[@ettoresabella8484]

@@TexterEX he might drink blood

[@montycora]

It really worries me that people that do not study nutrition for a living are out thee giving advice about what people should eat. Protein is the most important macro nutrient for HUMANS, and a scientist like himself saying that you should reduce protein is soooooooo damaging that I have no words to describe. He is a credible professional, so what will people do? They will reduce if not remove protein from their diets altogether because they will think: the more I reduce, the younger I will look. And what will happen? People will develop sarcopenia, lose bone density and SOOOO many other things. Leave this kind of advice for dietitians and nutritionists....

[@puneethchalla6634]

It worries me more that people believe more in nutritionists than doctors/researchers who have thorough knowledge of our body’s physiology He is asking to cut down on protein, not bring it down to 0g

[@montycora]

@@puneethchalla6634 - do you understand why there are specialized people in every segment? So you think all other professions can replace and know better about nutrition than dietitians??? Really? You do understand that we study the body's physiology as well and all the nutrients involved in it? And further more, we understand this as a whole, not just a separate part. There are daily requirements for protein and if you decrease it without knowing what you are doing, which is what he is suggesting, you will cause harm. But of course, he knows better than someone who spends 4 years of their lives studying this particular matter... Oh, please!!! Why do doctors refer people to dietitians then? your comment is just so ignorant that it makes me wanna cry...

[@freepagan]

You're supposed to cut protein down not cut it out. You'll still get the essential amount without overdoing it. What he's saying is absolutely true.

[@montycora]

@@freepagan - The point is that there is an amount that the body needs DAILY and that varies from person to person. I am sorry, but as a nutritionist it is better to over do it that under. What is the point of living longer full of health problems? That is the point I am trying to make. These things are tested in rats, a complete different profile and digestive system than ours. There is no real reliable randomized controlled trial in humans for long enough to really prove this theory. Just because ONE guy said so, doesn't mean it is the real deal. There are lots of dangers to under eating protein, that is why this is a dangerous advice. He has no nutritional knowledge or reliable sources to be making these claims. Anyone filled with botox and plastic surgeries can "look younger". This guy has money to take very expensive supplements and yet he is on youtube telling poor people to cut down protein, the most essential macro nutrient that we need to have a healthy body composition.

[@hermanharper4594]

Cup of beans everyday is good for protein. Whole foods plant based high fiber nutritionally dence diet. Don't need as much protein as you think add B12 supplement coverers everything fat's carbs and protein grain's beans nuts and seeds. And you don't need to get your protein from animals most animals are plant based high fiber diet. Strong like Bull . Ask gorilla where he gets protein from 🐄 RINO horse hippo 🦛 strong as F...k . Blue zone people very little meat

[@le832]

The thing is that lay people (non scientists and non MD) are self-experimenting and doing their extensive research but are not given credit. I wish these professionals would pay more attention to people who’ve claimed to cure late stage cancers and other illnesses through extended fasting. There are also those who routinely fast 5-7 days a month or quarterly with no problem. I like what some of these professionals are studying but they usually seem to talk more than walk. Sorry, he’s advocating fasting but can barely do a 3-day fast himself? In the fasting community, that’s kind of lame. If you’re an experienced faster, 3-5 days should be a breeze.

[@asbestosflake5749]

I’m very slim and I feel like death after a few days of doing 16/8. 14/10 seems to be the max I can go to consistently

[@Fearzero]

It's not ideal for thin people. I did 1 day every 2 weeks 24hrs and lost way too much weight.

[@mustafafh4402]

Do not fast if you are slim you need to fuel and nourish your body before you get into these kind of fasts, its exactly like exercising, if you dont fuel your body the right way, you will feel tired and exhausted, and it may harm you, as an experinsed in fasting i can do easily 1 dry fast and even 3 days, but you need to eat healthy in order to fast and repair your body and i dont suggest you fast everyday, thats not good for the human body and i dont care what anyone says, you should fast atleast 2 days a week, or every other day, you eat one day and you fast the next day and in the end of the day you eat a small meal, thats the best type of fasting, no 16 hours everyday bullshit

[@N7_YES]

Try 18/6 it will help you to be healthy

[@amperage8032]

As a slim, trying to maintain and even build muscle individual, but also wants the health benefits of fasting/autophagy, I understand. I’m trying to find the balance. I usually go 12-16 hours. There are different accounts of when the benefits of fasting occur but hoping I’m receiving some health benefits. From a muscle building standpoint which is critical for healthy aging meshing the two poses its challenges.

[@094340]

@@mustafafh4402 Daily IF is not "bullshit". It's not a fad, it's a way of life, there are many people successfully utilizing it and enhancing their health in myriad ways. If your fasting program works for you, great. But don't shit on the many people who are having great results from having a daily fasting window. You have nothing to support your harsh criticism except your own opinion, which any thinking person should take with a boulder of salt. I do agree that very thin people should exercise caution when it comes to fasting, for any length of time, but even they can benefit from perhaps a weekly 24 hour fast, as opposed to daily IF. Yes, even thin people need to give their digestive system a rest, as it can help to restore equilibrium to their overall health.

[@regplate2923]

By any chance is there a filter on this guy to make him look younger?

[@montycora]

yes, botox.

[@harper07harper]

You wouldn't believe this guy is 78!!!

[@Zanuka]

Isn't he 53?

[@harper07harper]

@@Zanuka He's 78!! He has aged very well!!!!! Eat your veggies Zanuka!!

[@LeratoM98]

👀 LIES

[@harper07harper]

@@LeratoM98 He's 78!!!

[@the_academy12345]

51

[@landosazo7506]

compare the life span of a tortoise versus a Jack Russel - one slow versus one that is jacked-up

[@094340]

Ridiculous comparison, one is a mammal, the other a reptile.

[@yb4194]

I read that actor Morgan Freeman only eats once a day , dinner & in the mornings he only drinks black coffee.

[@ZeusHelios]

David Sinclair's nose looks bigger. He's not lying to us is he? 😂 He also looks younger.