IF THE WORLDS DEADLIEST DISEASES WERE PEOPLE

[@LavenderTowne]

Hey guys! The Hazbin video had an error so I'm still in the process of remaking it! It'll be reborn soon but I hope you enjoy these creepy character designs in the meantime!! :3c

[@glitch7648]

Yay! I really wanted to see your take on them but I wasn’t able to watch the vid before you took it down lol

[@kuki2800]

take your time! and i think the hate for the 1st video was so unecessary.

[@FitMuffin]

Wut was the mistake?

[@achiblitz_]

I can’t wait! Take your time ^_^

[@RylieLightBulb]

Sorry about all the drama that video spawned, I hope you're doing well and I can't wait to see the remake! :]

[@eveejojo]

"She don't bite" *rabies girl foaming at the mouth trying to chomp down on someone* "YES SHE DO!"

[@typhoonboom]

oh my god, the legendary vine

[@Angelikaliu1331]

"Hey how yo-" **Aggressive borker noises** *_"AEÆ🦅🦅E-"_* *_"GETCHO FOKIN DOG BCH"_* "It don' bite" *"YES SHE DO-"*

[@YoEmoMom]

Look who found out about irony

[@R3DD..]

@@typhoonboomevery time someone references it i hear it in my head LOL

[@typhoonboom]

@@R3DD.. fair lol. i do too

[@NearsightedNarhwal]

I love watching a soft voiced lady draw spooky fellas

[@sillykel]

She's so pretty too ^u^

[@goatcheesee]

splatoon callie pfpf spotted in the wild 🗣️🔥

[@Can-Confirm_IwasDazaisGl0ck]

Callie pfp! And yea

[@Aprilwow.x3]

Splatoon pfp spotted

[@8ahampster]

CALLIE PFP OMG

[@wolfc9078]

I love how the prion disease character looks to be absolutely starving to death, because to my knowledge that tends to be the main time when when cannibalism occurs, at least in animals.

[@pappanalab]

It reminds me of chronic wasting disease too. It’s another type of prion disease that we see most in deer and their relatives

[@MarielWhalley]

Sometimes the prions can survive even longer than composited bodies, so wild animals can just be eating plants that still have animals remains D: honestly my fear between prion disease might be even higher than rabies

[@GingerJinji]

Malnourished ahh

[@moonoftheblood]

Cannibalism is pretty normal in several species of animals

[@ahorseofcourse7283]

​@@moonofthebloodYeah, it's not a hobby for the faint of heart.

[@sophiemcgeorge6623]

Lavenders voice: 🥰😚🩷🌸🌷 What she’s talking about: 🥀☠️🔪⛓️

[@corychapman796]

Haha 😝😊

[@ImTooLazyToThinkOfAGoodHandle]

you forgot🦠

[@eastdakota6954]

meningitis is genuinely one of the most terrifying things to me. every time i have a headache, i have the thought "what if i have meningitis?". it also tends to come along with "what if im having an aneurysm?"

[@redmegarex]

same

[@hvbg]

One thing you forgot to mention about rabies is that you don't experience any symptoms until it's too late, and by then your brain will have mostly turned into mushy goo from how the virus destroys your nervous cells

[@lunasills8031]

this is what scares tf out of me with rabies. I mean, it slowly but surely travels up your spinal cord to your brain, and over the course of years and years it'll eventually get to your brain. You'll get a headache, just a normal one, nothing that is horribly concerning. But once you feel that headache that is indistinguishable from any other headache you've ever had, you're already dead. Technically you're alive for another few months, maybe a year or so. But you're dead, you have no chance of surviving. Only one treatment is possible to "cure" it, and it'll leave you severely brain damaged

[@lunasills8031]

Which is why it's so damn important to get that vaccine if you've been exposed, or even think you might've been exposed. It's quite literally the only thing that can save your life

[@helixxia9320]

Only 1 person ever has survived rabies after symptoms occured. It it virtually impossible. I read they are doing research on her to find out how she didn’t die. since rabies is usually a death sentence she is a mystery

[@Dea1986]

​​@@lunasills8031the typical onset of Rabies is a few days to 2 weeks after infection, and after that it only takes 4-10 days for death to occur. Depending on where the infection site is, onset can take longer -as far as I'm aware there's only a handful of reported cases with an incubation period of more than a few months- but yeah, after someone becomes symptomatic, they typically have less than 2 weeks to live before death

[@Dea1986]

​@@helixxia9320actually 5 have survived! The Milwaukee protocol, - used after onset of symptoms associated with Rabies and other Lyssaviruses - has been used a total of 36 times, and 5 of those people survived. It's done by putting the patient into a medically induced coma and pumping their body full of antiviral medications, ketamine, and amantadine. There are ethical concerns brought up alongside the Milwaukee protocol due to its low success rate (14%), as well as the side effects that may occur while in the medically induced coma, like uncontrolled hypotension, respiratory failure, and sepsis resulting from immune depression. However, I'm unable to find any studies that cite brain damage as a side effect of successful treatment using the procedure, leading me to assume that any brain damage that occurs after survival is instead a result of the symptomology of *Lyssavirus*. Hope you got to learn something new today :)

[@wowitscoldout1119]

Favorite thing about rabies is that it probably explains the uncanny valley. When we were evolving and say something not quite right, one of the members of our pack acting strange , aggressive, paranoid, paralyzed, or a prey animal acting like that too. We learned that when something isn't quite right, it's unpredictable and dangerous, so we developed the uncanny valley as instinct so we'd stay away from them

[@internetlurker1850]

Diseases that are contagious and mess up your physical appearance and behaviours contribute to it as well, when something just seems "not quite right". If you look at pictures of people that have diseases that affect behaviour and/or physical appearance, it can certainly trigger the uncanny valley effect.

[@Amy_the_Lizard]

Not just rabies - a lot of other diseases hit the same "something isn't right" feeling too

[@s0viet_gam3r]

Yeah, also something that looks human but isn't is usually a very sick human or a dead human, which you wouldn't really wanna get very close to.

[@solar_co]

This and extinct species of human we used to live alongside with

[@pluddingcupp9783]

@@solar_co. Wasn’t that just a theory? Or a misconception?

[@damprat141]

Prion diseases are actually so fascinating on a chemical level , they are not like bacteria or viruses , but actually a improperly folded protein that causes a chain reaction unfolding other proteins in your body

[@juniperflutegacha7496]

The fact that there’s no cure scares me

[@DG_Toti]

@@juniperflutegacha7496the fact that somehow a misfolded protein is a more dangerous contaminant than most forms of bacteria and viruses and can’t be removed unless you straight-up destroy the thing it’s contaminated is really creepy to me like, it feels wrong that a simple protein can resist things that other deadly things can’t

[@plshalpmeh7941]

if a prion was humaniod, it would be a smol lil robot that glitches a lot

[@Someone-hx1lc]

Sounds quite similar to how Cancer operates.

[@damprat141]

@@Someone-hx1lc that's not how cancer works at all, cancer is a mutated cell that continuously reproduces, it actively infects and responds to stimuli, and it doesn't reformat other cells it just eats and reproduces

[@ClaireBostwick]

When my brother was born a couple months later he had a rash on his back. My mom took him to the hospital worried since he was still a baby and they life flighted him, they kept on pulling out spinal fluids and they weren’t quite sure what he had but they diagnosed him with meningitis. I don’t really remember it because I was 2 but I remember how scary it was for us. He survived and is a completely healthy kid

[@zelldincht6134]

Fun story: I'm a Veterinary Technician and at my old job I was bitten by a Raccoon because my boss wanted me to restrain it without sedation for a rabies vaccine. They didn't quarantine it, they just let the owner take it home. The owner of the Vet Clinic told me not to go to the ER because they didn't want to get in trouble because they weren't supposed to be seeing raccoons. There is a separate license needed to treat non domestic animals. I had horrible night terrors for a month straight.

[@yourshoulderdevil5229]

Did you get checked for rabies???

[@jackblacksleftstomachulcer1869]

please get checked for rabies because rabies typically doesnt show symptoms until its too late, pretty sure its a several month window😭😭

[@sweetlittlenothing7696]

Please tell me you got the rabies vaccine

[@MocaLykke]

Glad to hear that you're not working there anymore, your boss was completely irresponsible! I'm assuming it's an old story but there's been cases of rabies symptoms showing up after several years. I don't think it's common, so I don't want to freak you out, you're probably fine, but you might want to bring it up to a medical professional and get their advice about it, just in case.

[@NoiseDay]

Did you sue them???!

[@LemonZestify]

i think this is my favorite way to learn about posions and sicknesses

[@nyasputin]

Indeed

[@LemonZestify]

@@nyasputin you don't perchance happen to listen to the cult of Dionysus do you

[@cinderstreaks4507]

I’m feeling devious

[@Buggdoesstuff]

@@cinderstreaks4507you’re looking glamorous

[@the_comfy_studioakawolfhor305]

@@cinderstreaks4507”you’re looking glamorous!”

[@Emperor-Quill]

There's a two sentence horror story I'll remember forever. "This is a Public Service Announcement. Rabies is airborne."

[@AnimationEvi]

😅 my door would be locked and fucking sealed bro

[@Battery-powered-organs]

good thing i’m a homebody

[@catbatrat1760]

oh shit

[@octaviusmorlock]

According to the CDC, that's a bit of a misnomer. "Inhalation of aerosolized rabies virus is one potential non-bite route of exposure, but except for laboratory workers, most people won’t encounter an aerosol of rabies virus."

[@The_ace_wolf]

Is it true that rabies is airborn

[@BubbleoelbbuB]

Fun fact about rabies is the reason they foam at the mouth and are scared of water is because rabies is mostly found in the mouth and water makes it weaker i believe. So the disease purposely changes its prey's behavior to make sure it won't become weaker in a sense which i find really interesting.

[@amnesiaa0]

rabies causes intense spams in the throat whenever the victim tries to swallow, thats why

[@Amy_the_Lizard]

Aspiring epidemiologist here! I really enjoyed this episode, and would like to touch on a few design features that - while not discussed in the video - are still quite fitting: 1) The emaciated appearance of the prion character nicely references Chronic Wasting Disease - a prionic disease in deer that causes them to lose the capacity to feel hunger, and becone emaciated (among other things.) I also like that the skull of the character appears to have been split open, since contact with infected brain tissue is one of the main ways it's spread (even if the brain itself isn't eaten, if any misfolded proteins from it contaminate an object that isn't properly disposed of, crosscontamination and an indirect infection can potentially occur.) If there's one thing I'd change, it's that I would've given the character dark circles under the eyes to reference Fatal Familial Insomnia, a genetic condition that all but garuntees that those who have it will eventually have proteins misfold in their brain, leading to a prionic condition that prevents them from being able to sleep, with death usually occurring for reasons related to sleep deprivation rather than the actual holes in the brain that usually kill prion victims. 2) I appreciate that the rabies character is female, as the scientific name of the virus is actually named after the Greek goddess of rabies and violent frenzies, Lyssa (yes the Greeks had an entire goddess whose main thing was being in charge of rabies. She also nade Hercules murder his family because Hera threatened her, and also sicked rabid dogs on a guy who peeped on her and Artemis bathing. That's pretty much all of her surviving mythos.) I would like to clarify that rabies doesn't simply cause a fear of water, it causes the victim to have violent spasms if they look at water or think about drinking - because this hurts, the patient typically exhibits a fear response to water because it's presence is causing them pain, so they want to get away from it. This doesn't occur in all cases though, and is thought by sone to be the reason why vampires (likely at least partially inspired by rabies) are said to have an aversion to running water. 3) I like that the meningitis character doesn't have visibile legs, as a common complication of meningococcal meningitis (one of the more common bacterial meningitises) is necrosis of the limbs, causing them to essentially die and rot off while the person is still alive. No idea if any of these were intentional or not, but I still thought they were really neat. Also, I can somewhat relate to the hypochondria thing. It's something I've rarely experienced myself (which surprises a lot of people considering that I have contamination focused OCD,) but I have fallen prey to it on occasions where I have a sudden onset of severe symptoms, or a combination of symptoms that's rather ominous - especially if it's things I'm not used to. I got sick a lot as a child (11 seperate cases of strep throat in kindergarten alone,) so the realization that sickness could KILL me set in a lot earlier than most people, which feuled the phobia, but it also meant that I got used to dealing with a lot of common symptoms, resulting in more of a "Oh, it's this again," response to them rather than a "What's wrong with me?" response like most people. I'd feel a certain sort of throat pain, and know it was probably just my old nemesis strep throat yet again, and thus avoid panicking about other, more exotic possibilities. I also find learning about diseases was very reassuring, in my case at least, since I know which are the most likely suspects, and which can probably be ruled out due to missing key symptoms, low probability, or lack of exposure opportunity - though I'm fully aware it has the opposite effect on a lot of people. (Which is why my mom got told not to research breast cancer when she first got diagnosed. It didn't stop her, but luckily she had the same response as me and felt calmer once her research reassured her that she didn't match the features of the worst case scenarios.)

[@AstraAintCool]

Greek here, I’m glad u know abt Lyssa:D

[@shaynakershaw9084]

D3m you wrote a essay I would never

[@sigamigs]

Prion be like: "yoink got your brain 😃"

[@cindyxs]

I GIGGLED AT THIS

[@JelloLovely-oi8rm]

Lmao

[@79bigcat]

@@cindyxs Hopefully not too much...

[@ilikecatsandtos2]

Ehehehehe

[@olliescrew5512]

LOOK OUT HE’S GOT A BRAIN!!

[@random_dragon]

Theres a song called "Suburbia Overture" and one of the lines is, "I got kuru from your sister and died laughing in jail" This makes significantly more sense now. Edit: Will Wood reference!!! 😁

[@IoSaturnalia17]

WILL WOOD REFERENCE???

[@random_dragon]

@@IoSaturnalia17 WILL WOOD REFERENCE!!!

[@mushy_stars]

EXACTLY WHAT I WAS THINKING ABOUT WHEN SHE SAID KURU!!!!!!!!!

[@mushy_stars]

THAT WAS EXACTLY WHAT I THOUGHT OF WHEN SHE SAID KURU!!!!

[@i_need_a_nap7981]

That song actually sparked an interest for me in prion diseases so seeing this video made me happy

[@stellarstrategygaming1062]

fun fact with prions, they can also be inherited and can be somewhat spontainious. For example a family in italy has a prion disease that gradually will stop them from ever being able to sleep again by the age of thirty or forty and results in death, while some forms of dimentia are also theorized to be related to misfolding protiens

[@chickadeestevenson5440]

yup and it's HORRIFYING. Also sometimes your proteins just to "fuck you" and misfold. And it's worse for Deer, as there's no cannibalism needed. Just overcrowding. Chornic Wasting Sickness is HORRIFYING.

[@YouveBeenMegged]

Oh yeah, I think I’ve heard of that. Fatal Familial Insomnia, right?

[@SocksWithSandalsEnjoyer]

​@@YouveBeenMeggedI remember I watched a video reporting on a man who had suddenly developed fatal insomnia, and he documented the entire downward spiral on his KZbin channel. It was both haunting and heartbreaking to witness-- his mind was basically rotting inside his own skull and at the time, he could do nothing about it. The worst part about his story though, is that he was a loving, single father to his only son.

[@YouveBeenMegged]

@@SocksWithSandalsEnjoyer Dear gods, that’s awful. Hope his kid is at least doing ok now.

[@alllisda_idiot7087]

@@SocksWithSandalsEnjoyer what KZbin channel was that? I want to check it out.

[@faerykaye]

Spinal meningitis almost killed my grandfather when he was 7 or 8 years old. He told me all he remembered was feeling kinda sick and way too warm and going to bed after coming home from school and apparently he never came down for dinner and his aunt and uncle went to check on him and he was in a coma. The doctors told my great grandparents that if he survived he'd probably have brain damage, be blind and or deaf, and most likely be unable to communicate verbally ever again. Miraculously he survived without any of those things. He's 72 and is still engaging in his lifetime hobby of running and is coaching my old high school's cross country and track teams. He was so lucky to recover, let alone without any brain damage or other complications.

[@VILovestein]

0:00 intro 0:06 Piron 3:32 Marburg Virus Disease (MVD) 7:32 Rabies 13:21Meningitis 16:38 finished diseases group 16:49 outtro

[@Sunny-Bunny7567]

Nobody can convince me that diseases like these aren't the reason we have the Uncanny Valley instinct. The odd behaviour they cause perfectly fits with the "Looks human but doesn't really act like one" panic of the UV instinct. When the new humans saw others act like that would have recognised "That human(?) is acting weird. Last time someone acted like that they died really horribly and the ones they infected did too. Better get the hell away from them so I don't suffer that fate." and now that stuff is just ingrained in our monkey brain

[@airacummins5076]

Well the uncanny valley is for things that almost look normal,

[@SomaelTentacleHair]

yes, I've read about this as well and it makes perfectly sense

[@bingusdingus7417]

That also sounds a lot like a curse. Maybe a prion disease is the origins of a cupacabra or w@ndigo belief, where if one cannibalizes another they'll become something like that but not quite, that hunts for more.

[@Mariana-xk3bp]

Uncanny valley effect likely explains the skin walker legend

[@vinx.909]

Not a bad hypothesis.

[@ZK-ib2wp]

The most horrific symptom of prion disease that I have heard of is fatal insomnia---damage to your brain/nervous system such that it makes you not be able to sleep until your body gets so tired you die

[@siorganism]

And it doesn’t even happen because of cannibalism, sometimes prions just forms simultaneously

[@aspillust]

@@siorganismnew fear unlocked.

[@tasty.microplastics]

Also when researching ways to stop sleep during the cold war, there was a whole experiment on this gas that effectively stopped war prisoners (that were told that if they stayed all 30 days awake they would be freed) and they started acting strangely, then they started eating themselves, im talking ripping out veins. So obviously the gas was paused, but they were begging for more. Idk it just kinda reminded me of that, especially since there were pictures 😭😭

[@alicepen]

@@tasty.microplastics That’s a creepypasta, the Russian Sleep Experiment. It’s not real at all. That doesn’t discredit horrific experimentation in the name of civil and domestic defense, but that didn’t happen.

[@ZK-ib2wp]

@@siorganism i think you mean spontaneously?

[@J.J.DoeArt]

Meningitis, even when survived, can be really scary. I'm friends with a really lovely girl in my college who had it as a baby, and while she recovered, it has left her with Cerebral Palsy, she can't walk without a walking from and has a visible lazy eye along with other health complications, and she got off on it lightly. It is definitely scary and can hit anyone at any time.

[@EmbalmerEmi]

It can also cause blindness and deafness.

[@HeloFromStrangerc]

@@EmbalmerEmi My dad had it when he was 3, lost 70% of his hearing in one ear.

[@paparoniandchaese7966]

i think about it a lot because i had meningitis back in 2020 during lockdowns and somehow came out the other end with no long-term affects. i was hospitalized for about a week i think, but i spent the whole month basically down for the count sick or recovering. i don’t even remember most of it. though it was viral and not bacterial, which is less serious. still wild.

[@Will-O-thee-Wisp]

My sister was 16 days old when she passed from ecoli meningitis. My mom noticed she cried a lot with diaper changes and car seats because of the pressure it put on her abdomen. It had spread and started to affect everything. My younger brother also got it as a newborn too, but they were able to catch it fast enough that he was able to make it, and doesn’t seem to have gotten any negative effects afterwards, he’s 19 now. After probably about a month of being in the hospital, he came home Christmas Day.

[@leilanix4life]

im really sorry for your loss with your sister. i know she’s in a better place now

[@aino-kaisav5504]

7:27 Man, this looks so much like a character that one of my friends could make. She's really interested in military suits and antropomorphisizing non-living things. If I happen to meet her someday again (we haven't seen each other for years), I should probably recommend this video to her.

[@aino-kaisav5504]

12:50 Also same. Illnesses were to me, one of the most terrifying things in the world.

[@detectivesupersomething5649]

the little rash marks at 7:31 looking like creepy smiley faces was such a great subtle detail

[@gothfoxgirlAO3]

If you decide to do a part 2, may I suggest: -Radiation Sickness -Black Death(Already done) -Leprosy -Tuberculosis(Already done) Edit: I completely forgot about her plagues video let me redo this lol -Radiation Sickness -Leprosy -Necrotizing Fasciitis -Dysentry

[@Dead-idiot]

She already did Black death and tuberculosis

[@lizared.real.notclickbait]

OOO YEAH RADIATION SICKNESS its so interesting id love to see that

[@puppet_boy74]

i love radiation

[@anastasiap6253]

I was about to say that Lavender drew dysentery before… but I checked and it was actually cholera 😂 My additions: Spanish Flu Smallpox Polio Malaria Sleeping sickness AIDS Nipah

[@DG_Toti]

I’d also like to add the suggestions of Alzheimer’s disease-type dementia and mucormycosis/black mold infection, both of those terrifying me for wildly different reasons

[@Gachakitty-og5hx]

Lavenders voice: ☺️ What she draws: 💀

[@Angelikaliu1331]

The topic: 😨

[@FizzabelleStudios]

The music: 🎹🎹🎹

[@GremlinArt18]

Fr

[@scaryrubberduck]

The air: 🗣️❌🗣️❌

[@pineapple3555]

us: 😰😰

[@S0ap_Bvbbl3z]

The prion girl looks like someone who would commit war crimes and get away with it

[@pandoratheclay]

Prion diseases aren’t exactly the most curable, or findable in a timely manner So yeah, commit war crimes and get away scot free sounds about right

[@Nicola-_-Vera]

CURSED CAT ALASTOR PFP?!?!?!?!??!!?

[@Nellie-The-Witch]

Oof

[@achiblitz_]

@@Nicola-_-Veracursed cat Alastor is infesting the internet and I’m here for it

[@TrueLadyEvilChan]

She already had gotten away with it.

[@rosiekitten3828]

I love the fact you include the spiraling shape of the broke prions for the character in her curls and ribbons.

[@jaylubke5376]

would love a video on characters based on terrifying experiments in psychology (stanford-prison-experiment or milgram experiment for example) i'm obsessed with these kinds of experiments and i think it'd be super interesting to see characters based off of those

[@noname.3774]

The second guy looks more sad to me than scary. Like he’s regretting what he’s created when it’s too late

[@Mariana-xk3bp]

Oppenheimer

[@starfishx7052]

Russian oppenheimer​@@Mariana-xk3bp

[@nikbowman3478]

He is bleeding from his eyes.

[@slutfortttt]

@@nikbowman3478yeah, lavendertowne said that, it’s the expression of the character

[@diyakittu]

Prion diseases are absolutely horrifying yet so interesting! Especially seeing as it's already an umbrella term with many specific diseases with varying symptoms and causes. It only really makes the iceberg even deeper, and how little we know about these diseases more apparent. Especially seeing as how little research has been conducted about them

[@Angelina_Davis25]

The moral of the story is don't do cannibalism kids. Who else thinks Lavendertowne voice reminds them of rain for some reason?

[@siorganism]

Funfact you still could get prions even without eating someone , sometimes your proteins just go “man fuck you” and misfolds and honestly thats fucking scary

[@AlmostOtaku7]

If you ever are forced to resort to cannibalism in a survival scenario (which is rare, but just in case), best way to avoid prions is to not eat the brain. Not foolproof, but any little bit helps in those (RARE AND HOPEFULLY AVOIDABLE) situations

[@siorganism]

@@AlmostOtaku7 funfact, the people who were more prone to getting kuru in the fore people were women and kids because they would eat the brains/organs of the deceased (it was for funeral reasons) The men got muscles so they are less prone to getting kuru Still scary nontheless

[@Angelina_Davis25]

Best way to avoid some things with cannibalism is not to do it because there are things that come just isn't worth its better to Starve.

[@AlmostOtaku7]

@@Angelina_Davis25 For some people, sure. But not for others. And there IS ethical cannibalism. It's not a choice you're allowed to make for others, especially when in such rare and tragic circumstances.

[@chevaliergg5012]

as the freak-kid that was constantly pestering my mom with questions about diseases, going "what does this one do?" "is it really bad?" "and what does this one do?" (mostly just to scare myself for fun??), this appeals to me on a weirdly... nostalgic and comforting level.. very odd, but the designs are absolutely lovely and i still have a strange love for learning about dangerous afflictions

[@leelamb9789]

me: has a headache Lavender: one of the signs is a headache me: starts writing my will

[@unngjerde5064]

I love watching my favorite youtubers when i'm dying of a cold

[@JustCallMeBeeker]

Hope ya get better soon

[@nirvannamendoza2891]

I hope you get better soon too ^^

[@privacy-is-nice]

Get well soon

[@Rock-xb5hh]

Hope you get well soon

[@JelloLovely-oi8rm]

Get well soon!

[@CupRamenZ]

She sounds so calm while talking about literal death 😭

[@YouveBeenMegged]

If this is going to be a new series, may I suggest: Polio Smallpox Brain-eating amoeba Malaria Ebola Encephalitis Disease as a concept is such a terrifying thing, and art with themes of disease is weirdly fascinating because of it. I would love to see more of this!

[@DG_Toti]

Hey, you and I agree that the brain-eating amoeba would make an interesting addition to this series! Nice

[@Blue_bird1e]

Idk if this counts, but maybe include dengue fever too? Idk if it counts

[@agentowo7854]

Also Yellow Fever Scarlet Fever Botulism Another suggestion but I know it isn’t an illness is Radiation Poisoning. Something about the false recovery of Radiation Poisoning is just horrifying

[@Angelica02024]

Hey I have a question. What's that desease where you forget something in like a second? My mother's auntie happens to have that desease.

[@agentowo7854]

@@Angelica02024 Dementia?

[@bananasarebetterthanlifeitself]

I have fibromyalgia, and was really surprised when you mentioned it. like you can get it as a symptom of diseases. Makes a bad situation even worse. must suck

[@elnic_kai]

this video has been scarier and more disturbing than anything you've ever put out. not a single creepy drawsta, not any other things as people. the poison humans were so tame compared to this. so good.

[@Kawaiitwo]

If you ever make a part 2, it’d be interesting to see something like Naegleria Fowleri, the brain-eating amoeba. It has around a 98% fatality rate, but thankfully, cases are very rare. Since it’s an amoeba that lives in warm, freshwater environments, maybe some aquatic creature person would work as a way to portray it.

[@YouveBeenMegged]

Oh yeah, I remember being weirdly obsessed with this one for a while.

[@aino-kaisav5504]

I learned about this from a horror visual novel that was called Parasite in Love. Sounds really terrifying and suddenly the fact that my home country has relatively cold lakes and rivers even during the summer doesn't feel that bad at all.

[@ProfessionalBugLover]

YES

[@crescent_sun482]

Fun fact, it can NOT survive in saltwater. That's why, as a Southerner, I never swim in freshwater, only the Gulf.

[@DG_Toti]

@@crescent_sun482also fun fact, it apparently can only enter your cerebrum via the sinus, so you’re fine as long as you don’t let it get up your nose or into that little connecting area between your nasal cavity and the back of your throat

[@ssapphire7781]

Hearing Lavendertowne talking about Rabies makes me realize it feels very intentionally designed to be like,,, the most infectious disease. Biting someone while your saliva is foaming and extreme is the perfect way to transmit disease?

[@amiroquet7476]

Rabies is the closet thing we have to a real life zombie virus

[@BaconQweenRoblox]

@@amiroquet7476ikr!

[@kleeeia]

@@amiroquet7476exactly

[@ssapphire7781]

@@amiroquet7476yeah exactly

[@BoneyardWastelands]

My favorite Disease is Chronic wasting disease (CWD) for short. a prion disease that affects deer, elk, reindeer, sika deer, and moose families. Love your art, you inspire me to pick up a pencil and draw again.

[@SodaCider641]

CWD would be a wendigo-like creature.

[@biscutboi813]

Those are all super cool! You are the perfect combination of calming and creepy to scratch that morbid itch that I've always got.

[@22CAJ]

You are really good at making art that is terrifying in a very understated and subtle way, and I love it. I think the horror genre really benefits from relying less on extreme gore and very obvious, in-your-face danger and more on things that tug on the back of your subconscious and generate a sense of unease from within. Great work.

[@BendyStrawNeck]

The characters you make are always so... cosplay-able, you know what I mean? These would all be soooo interesting to create costumes for and stuff.

[@dumbartist864]

FRRRR

[@pappanalab]

Oh my goodness!! Lavender knows about Prions! As someone who knows far too much about prions, I’m ecstatic! I think one of the scariest things about CJD is that it’s not only caused by ingestion of prions. The most common cause is random misfolding of the heathy PrPc protein into PrP protein. You can do everything to avoid it and still get it because ultimately you can’t do anything to protect yourself from a freak accident during otherwise normal physical process.

[@chickadeestevenson5440]

or the gentic varient.

[@ThatZombieCrow]

Prion diseases are interesting. I have read so many articles over Chronic Wasting Disease and scrapie and other prion diseases just because of a character I’m writing based off of the Not-Deer and that got me looking into CWD and that led me to having a minor problem and obsession with prion diseases

[@aspillust]

the fact that your proteins can just screw you over like that out of nowhere is absolutely terrifying to me and i may or may not have nightmares about this

[@user-oh1jg]

youre so real for that!!!

[@j3llyfish_enjoyer]

holy moly jellyfish!! i love jellyfish sm

[@bone_dust8343]

Hey lavender towne!!! I just wanted to let you know youre not alone in that fear of having a deadly disease all the time. Im 15 and constantly terrified that i have ovarian cancer, endo, etc. Just the most crippling anxiety. Knowing that you also have that and have lived as long as you have and gotten past it is very comforting. Funnily enough, the pqrt about prion disease definitely drove me into a mini anxiety attack lol.

[@SpringStarFangirl]

As someone who potentially has endometriosis, you'll probably know if you have it. For years, I'd had incredibly painful menstrual cramps- doubled-over-in-pain-popping-advil-every-four-hours pain- and that's generally the most obvious symptom of it. If your cramps are mild, then I don't think you have much to worry about.

[@aspillust]

the more i learn about rare/deadly diseases, whether it be from my dad talking about work stuff or from the internet, the more i fear for my life on the daily. having anxiety is Not helping me on that lmao.

[@bone_dust8343]

@@aspillust I totally get it I have the exactness thing!! I wasn't even able to finish this video lol

[@bone_dust8343]

@@SpringStarFangirl I'm sorry you've had to go through that :(. This is rather reassuring though. I've dealt with very severe cramps but 91 day birth control helps

[@SpringStarFangirl]

@@bone_dust8343 I'm also on continuous birth control- specifically a progestin-only pill- and it's helped a lot! Hormone stabilization absolutely helps.

[@punishedphr1610]

I wanted to say that i still love your work and you're one of my favorite artists ever

[@Redboots]

oh big mood on the hypochondria. I used to get sick a lot or have anxiety attacks which caused physical symptoms when I was a kid, and combined with a family that's very much 'you don't see a doctor until you're Actively Dying' I got told I was a hypochondriac a LOT as a kid and it kinda ruined my ability to actually tell when something is bad... about a month ago I had a severe reaction to one of my meds and couldn't keep water down and I was sitting in urgent care going 'man what if I'm overreacting'. I think being told that also predisposed me to being Super Paranoid about being infected with something incurable like a prion disease, but that's kinda something my highly disordered brain does, I get very paranoid that my powerpoints will fry and set the house on fire for one example lol but your drawings are so cool and have such meaning stuffed into every aspect that it's kinda rewiring parts of my brain to be less paranoid which is neat as hell

[@veaceslavstoianov4378]

Lavender town never fails to rip my limb apart one by one as I scream in excrutiating pain and agony meanwhile my consciousness slowly fades away

[@random_dragon]

Lmao, are you okay?

[@sillykel]

Lavender towne never fails to kill me while talking to me about deadly diseases in a soft voice

[@cosmix1891]

Bro What 😭

[@Fawnfreckle]

LMAO????

[@olliescrew5512]

😭

[@amer6706]

The Prion disease one was so well designed. The emaciated figure made me think of Chronic Wasting Disease, the prion disease found in deer.

[@Marilynn_1275]

Yeah.

[@LGus-gr9wo]

Loved these designs Gotta have "Naegleriasis" (the disease of the Brain Eating Amoeba "Naegleria fowleri") for a part 2

[@carp_piratebird]

YES

[@foxpatternedferret476]

Cordyceps! It doesn't affect humans, but the fact that it specializes from insect to insect is horrifying

[@toxicdragon323]

Yes, the brain eating amoebas! Naegleria Fowleri, Acanthamoeba, and Balamuthia Mandrillaris! All three are brain eaters!

[@catanmeowmeow7998]

Yes... These little amoeba fuckers made me absolutely terrified of any water getting in my nose

[@DrL0gical-x7h]

Definitely smallpox or ebola next

[@octopusyogurt1883]

Another prion disease that is absolutely terrifying (but only affects animals) is chronic wasting disease, which tends to affect deer. Essentially, it causes the deer to completely stop functioning, to the point where they don’t eat and die a slow, painful death from wasting away (hence the name)

[@McMackster]

Beautiful and inspiring work! I had a similar hypochondriac moment where I was constantly afraid that I had or was going to contract cancer in some fashion... Can't wait to see more of your unique style!

[@kittentea4101]

The way she's able to humanize concepts such as deadly diseases and create such designs out of it will never not be amazing to me, I wish I had as much creativity as hers!

[@jonhirom]

These ideas of turning random stuff into people is actually really cool. And the characters turn out so interesting in the end ✨

[@-pink3-756]

These all sounds so scary like I love lavendertown but- 😭

[@zeapringle]

you physically couldntve watched it tho??

[@-pink3-756]

@@zeapringle im watching it rn its jst a lil scary

[@internetlurker1850]

Well she doesn't have "Lavender Town" in her name for nothing.

[@helixxia9320]

I agree it is terrifying especially the uncurable ones 😰😰

[@Sparklezz._Lightning]

but?????

[@DrBright5558]

Prions are terrifying. Not only are they 100% fatal, they are also extremely hardy. Prions can survive the heat of burning wood, decades in direct sunlight, and the only way to remove them from a room is to flood it with hydrogen peroxide for days on end.

[@ItsDemonsReality]

‘This is a disease that will make your heart stop and rip your flesh out and eat you from the inside out’ I love how she’s just so chill when explaining and drawing these

[@randomgoats]

The first one freaks me out so much, especially because of the awful treatment of the cows in intensive farms :( the whole thing feels so dystopian and awful.

[@the-postal-dude]

thank god that practice was phased out... i'm personally extremely bothered by chick culling, which is unfortunately still a thing that happens.. at least companies are looking for alternatives, it's so unneccessary and inhumane

[@Corven512]

I would just like to say real quick that, by far your art style is my favourite, just the love you put into all your character designs is incredible, thank you for making content and creating for all this time.

[@dinoheartnerd2265]

Oh my GOSH Haley, for a long time I have actually been secretly wishing if you could make another one of these videos centered around making character designs based on science and medical-related stuff, so this has made me SO SO SO excited, AAAA

[@iinkrott]

When i was 7, I got this.... absolutely insane headache. Couldn't sit up without screaming type of pain, and I've always had a rather high tolerance. But this was something else. It was so bad that I was taken to the hospital and given a spinal tap to test my spinal cord for meningitis. I still remember seeing my blood and stuff and the giant needle after lol. And to this day, 20 years down the road, I still sometimes feel the spike of the needle in my lower back. All of this to say, your meningitis design is spot-on as far as the feeling of the whole experience goes. Blinding white and red hot spiking pain that make your head feel swollen and swimmy. It wasn't meningitis, by the way. I just had a severe sinus infection 🙃🤣

[@MilkIsASauce]

Something with rabies that defo scares me is the realization that when you die, your family and friends will remember not who you were, but who you became- IT'S SO TERRIFYING TO THINK ABOUT JNCISLAHPFHIE

[@KitYippee]

I thought it said “disasters” and i was just thinking “is she gonna draw nine eleven anime girls”💀 Edit: OMG I JUST NOTICED THE RASHES ON MARBURG VIRUS KINDA LOOK LIKE SKULLS

[@LocalPest]

why do i want to see that..? edit: IT'S OUT OF CURIOUSITY, I JUST KIND OF WANT TO KNOW WHAT THAT WOULD LOOK LIKE

[@olliescrew5512]

@@LocalPest💀

[@miik7064]

I’d pay to see that

[@Angelikaliu1331]

Lmao 💀💀

[@ProfessionalBugLover]

STOP I REMEMBER THE POST I SAW ON PINTEREST OF 9/11 PERSONIFIED

[@croissantnuggetnoelle]

Remember when Lavender did character designs for the four horsemen? What if these guys are like servants or workers for Plague?

[@floofy_birb]

This headcannon is my new roman empire

[@Amo_1732]

@@floofy_birb *100% agrees* ((Sorry for necroposting))

[@ethereal_doodles7120]

This is so scary bc my mom and I were attacked by an untrained husky today, and my mom was bitten. Thankfully, this dog was already vaccinated and did not give my mother rabies, but holy shit that really made this video extra scary

[@Koci_baklazan]

I absolutely love your vids❤ Im gonna get the comic "Unfamiliar" for my birthday . And your work is just so good! I really like your style and sometimes the vids inspire me ,they also keep me determined to not stop drawing

[@ThatZombieCrow]

So, I have spent the past 2 days reading, like, 16 different articles on prion diseases like CWD (Chronic Wasting Disease) and scrapie in sheep and mad cow disease, so it’s just a fun little coincidence that this video comes out featuring prion diseases. I honestly thought your design for the character was really good!

[@carolinecheney]

This is great! I got another terrifying and deadly disease for ya. Cancer. There's multiple types of cancer that affects different types of the body. And it can affect anyone at anytime, and it doesn't matter whether or not they're healthy or a young child. There's no cure for Cancer, but there's treatments. Unfortunaty, half the time the treatments don't work and the person dies. Cancer is so bad that EVERYONE has had at least one person in their family that had either went through Cancer or died from it, whether or not they're aware of it.

[@missiris4808]

This video is amazing, can you do more genetic disorders like scoliosis? I have scoliosis, thank goodness it’s not bad at all, but it’s very scary. scoliosis is a genetic disorder that pulls your spinal cord tight and makes your spine curve if it gets really bad it can crush your organs. I would really like to see you draw something like that.

[@galactic_studio09]

No freaking way, scoliosis reference?? (I had scoliosis too at one point, but I had it surgically fixed)

[@kurokura8379]

i have scoliosis too and recently got diagnosed. i was freaking out about it for a while but now i just try to educate myself abt it as much as possible, somehow that helps me.

[@ThatPangolin]

All of us bonding over our bad backs lmao

[@galactic_studio09]

@@ThatPangolin so real

[@Sagethegay]

I have scoliosis as well! I have to wear a back brace which a lot of people think looks like I broke my spine lol.

[@Sparkling34]

The sick, raspy, low energy, quiet voice fit the vibes perfectly.

[@klutzykaya6439]

thanks for this i was really struggling to articulate to a classmate of mine that cannibalism is not only morally wrong but it will literally kill you lol, also the meningitis passage was particularly interesting. A different classmate of mine recently contracted meningitis which is unfortunate bc he was like, three months away from being vaccinated? He's doing a lot better now but it's terrifying to know that it could happen to anyone, that kid was probably one of the healthiest people I've ever met aside from that. Scary. Great video! I love your designs as always! I think rabies is my favorite, i think the skull chestplate? bustier? (or whatever?) is particularly visually striking, especially since you put the teeth at the corners of her mouth like she's being forced to smile. Keep up the good work! :))

[@Beemy0s]

11:03 also if you get bitten by a squirrel or weirdly social raccoon! both of those things also commonly carry rabies. Oh and also it doesn't have to be a wild dog or anything. It can be a domestic dog that caught it due to not getting proper vaccinations. If you get bitten by a domestic dog and are able to contact the owner ask about it's shots. If you're not able to contact the owner go to a doctor because it's better to be safe than sorry. Rabies is horrific and painful for sufferers. Also even if the animal isn't foaming at the mouth it can still carry the disease in an early stage. Every stage of rabies once the person/ creature becomes aggressive is contagious regardless of hydrophobia. (I think) If you ever find a bat on the ground DO NOT TOUCH IT that is a very very common sigh of rabies. Also bats carry other diseases so if you do touch it wear gloves and if it bites go see a doctor ASAP! You can also get tetanus from a dog bite. And dirt. Which is how you'd get it from a dog bite. I got bitten by my neighbor's dog once like bitten bitten not just playful. I was dog sitting and the dog was fine with my mom but when I walked in he latched into my knee and I didn't scream or anything I was just like. "Uh..." and my mom turned around and freaked out. She cared for the dog and I waited in the car. I got home cleaned the wound with soap and warm water (do not use hydrogen peroxide it damages skin) while my mom called the doctor and asked them if we should come in. They said yes and made sure I was up to date on my tetanus shot and all that jazz. My mom also called the neighbor cause they're friends and asked if the dog had all his shots. He did. So the doctor said "If it gets anymore swollen, warm, red, or smells come back immediately." thankfully none of that happened and I'm fine. I did get paid extra. The dog is aggressive towards men (or was I dog sat him again recently and he was so much nicer). But yeah just an interesting story.

[@cubisttubist]

I love a classic Lavendertowne thing-that-kills-you-as-a-character video!

[@pommedeter7407]

This might be your darkest episode yet. I know you did a bunch of other videos for like poisons, chemicals and such but the description of those illnesses were particularly disturbing to me. But it was very well done and the art looks great! Very cool video, just a bit more spooky than I had thought (not a criticism)

[@c0smic__refl3ct10ns]

BRO I CAN'T HOW ARE YI1U SO TALENTED AND CREATIVE!!

[@SnoobertTheGoobert]

I love all of these so much!!! Every one of your videos is so interesting and it's a great way to learn about diseases!!!

[@mullac1992]

What I expected: A cute art timelapse What I got: New phobias.

[@NNsLivingRoom]

🥰 same

[@RobinIsForgetful]

her inspiration: 🖤💀🔪⛓🩸 her voice: ☺🩷😘🌸🍬

[@harleenquinzel1]

this is living proof lavender isn't bad at character design

[@IGOTTRIXUPMYSLEEVE]

She's never been!! it's just that.. _those_ .. were very rushed :')

[@savythenillerwaffer]

@M00N3CL1SPE What are "those"?

[@Chilycoldude]

​@@savythenillerwaffer Hbh redesign

[@Coolprayingmantis]

​@@Chilycoldude I can't find the video, did she get into trouble from it? :(

[@Mentalt-ish]

@@savythenillerwafferthose are my crocs…

[@tunamoose]

Ooo I love these! Prions are terrifying, but I love learning about them :D Great art as usual!!

[@Sugarcoda]

"Changes protiens..." wow that's interesting "Contracted through cannibalism..." *Oolp* barfs

[@LichenMarenakisen]

I absolutely love these ideas. I actually had an additional idea about rabies where the character could look excessively dehydrated as one of the most notable symptoms of rabies is hydrophobia

[@jessicadragonare7993]

It's barely noticeable but between the display of characters and the end credits at the end of the video around 16:49, the rabies character flickers and disappears while the rest remain.

[@annaritaprete6091]

Y'know what would be, like, awesome? A reverse kind-of creepy design. Like, if it's supposed to be normal but it has an element that is just strangely off-putting and uneasy. If you would like an example: a character with a scarf, but the scarf is actually a noose (y'know, the rope used for hangin')

[@DG_Toti]

I mean that specific idea has been done before but it would be interesting to see how she’d do a super subtle horror design

[@annaritaprete6091]

​@@DG_Toti Ah, really? I haven't seen videos like that-

[@Stardust_Fox]

My reaction as i opened the video basically "SHUSH I JUST WANNA SEE RABI- Oh nvm i can learn about others" "Prion can be acquired from canni-" "I'm interested"

[@Thesillytraveler]

she could be talking about the worst thing ever and i will still fall asleep to her voice

[@merriellenroselette5191]

Gosh I love love love this video. And I missed it when you'd make neat characters out of deadly things. I've got some more deadly ideas for you! Characters based off of venomous animals (starting from not too bad to maybe box-jellyfish or the Man-o-war) Characters based after deadly substances (asbestos is the only one that comes to mind atm) Characters based after the toxic old paints/dyes.(Prussian Blue to Uranium Orange) (There's a really neat youtuber who finds the toxic dyes/pigments and makes paint with them, (bekahart) She'd be a good source to find more colors besides doing your own research. ^_^ Kind of opposite of deadly, but turning road safety signs into characters would be interesting too. Anyway I'm rattling off, I can't wait to see either more of these diseases if there's any more to add.

[@owenheckmann6962]

Are you familiar with Urbach-Wiethe disease? Specifically one of the cases in which the amygdala (the part of the brain responsible for feeling fear) is damaged. Many of the sufferers are incapable of feeling any fear - which has interesting side effects (at one point, she was mugged at gunpoint and scared off the mugger through an inability to be affected by the threat of violence)

[@amethyst1062]

What other interesting side effects(Google will traumatize me if I google it you’re my only hope)

[@owenheckmann6962]

@@amethyst1062 The Woman who We have the most complete research on was nicknamed SM (for privacy reasons) and her fearlessness got her out problems that her fearlessness got her into. Also, strongly reduced ability to dream.

[@cactiandnothing9600]

I gotta say that the Viral disease (don’t know how to spell it) is my favorite! I like the Soviet inspirations and how he actually looks in pain! I also think it is hypothesized that rabies may be the reason that humans are so scared of zombies!

[@crepuscule3003]

your art and the way you design your characters is so inspiring to me ! I love your art so much especially miwed with spooky concept !! (also i cant believe bats give this many diceases ?? how am i supposed to live without a pet bat ??)

[@NoelaniMenard-wt7wp]

As a person who researches deseases and other deadly Illnesses on my spare time and at one point wanted to become a pathologist,I was shocked not seeing Ebola or Brain eating ameba.more than 90 percent of people that contract brain eating ameba will die.it’s rare to get but is extremely common in fresh waters in the United States .while many epidemiologist consider Ebola to be the second most deadly decease disease in fatality rates after rabies.third deadliest is Marburg which you drew both rabies and Marburg so you got them covered.brain eating ameba has the highest fatality rate while malaria is the most deadliest parasitic effection In human history.if we are talking most contagious desease it will be measles,if you are in a room with someone with measles 9 out of ten people in the room will end up getting it.The most deadly but common bacteria to humans in Tuberculosis.basically I hope if you do a part 2 you consider these deseases based on how deadly they are. Here are the list of them Ebola Brain eating Amoba Malaria Tuberculosis Candida auris Also Candida Auris is the deadliest fungus to humans.

[@HannahM-d4f]

Her talking about the symptoms is scary but the even scarier part is that for her to know this, ppl had to have these diseases and suffered these symptoms

[@zeapringle]

I would love to see a replica of this video but with fictional diseases!!

[@Coro_is_already_a_picked_name]

Hell yeah! I would love to see Lavender Towne draw hanahaki.

[@sunnysunsins]

Hanahaki beloved when

[@harpywiththebrownfeathers]

Yes :D

[@henrybenjamin7606]

I would love to see khara from subnautica guven this treatment

[@drjackbright2505]

Always fun to watch a new Lavender video. I actually had meningitis when I was younger, and I adore the fact that you’ve turned it into such an interesting character

[@cheesycheese8451]

I'm glad you survived it!

[@annaewrites]

If you like media that features these kinds of diseases (but like 100x times worse), I recommend The Maze Runner books/movies they portray the horror of it SO WELLL it’s one of my favorites ever

[@kimiko_ella3092]

My grandfather has Creutzfeldt-Jakob disease. He had a spinal surgery where they apparently had used an infected tool, but it wasn’t until about 20 years later that the symptoms actually started to show up, cause that’s how long it took for it to reach his brain. Once it did however, it was a very rapid progression with dementia-like symptoms, and he apparently started to only speak in German in the end, even though it wasn’t even his first language. 😅

[@loucievaconsin2698]

0:00 - Intro 0:14 - Prion disease 3:31 - MarburgVirus 7:32 - Rabies 13:20 - Meningitis 16:38 - Outro