Is Histamine Intolerance The Cause Of Your Mysterious Symptoms?

Most people are familiar with certain histamine conditions, such as the development of a welt from a bee sting or hives from a peanut allergy. However, symptoms ranging from brain fog to digestive problems, menstrual cycle problems, nausea, vomiting, edema, palpitations, and anxiety can all also result from issues of histamine intolerance. Unfortunately, this issue commonly goes undiagnosed, often resulting in years of ongoing frustration and suffering among individuals struggling to find the cause of their mysterious symptoms.⁣
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In this episode, Dr. Hyman sits down with Dr. Todd LePine to talk about how they work with patients to get to the root cause of histamine intolerance. They discuss the rising prevalence of mast cell activation syndrome (MCAS), how gut health influences histamine, and much more.⁣
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Dr. LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders and the neurobiology of mood and cognitive disorders. Dr. LePine teaches around the world, and has given lectures to doctors and patients at American College for Advancement in Medicine (ACAM), Age Management Medicine Group (AMMG), the University of Miami Integrative Medicine Conference, The Kripalu Center in Lenox, MA, and is on the faculty for American Academy of Anti-Aging Medicine (A4M). Dr. LePine is the head of the Scientific Advisory Board for Designs for Health and a consultant for Diagnostic Solutions Laboratory. He enjoys skiing, kayaking, hiking, camping and golfing in the beautiful Berkshires, and is a fitness enthusiast.⁣
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This episode is sponsored by Athletic Greens and Dr. Hyman’s Sleep Master Class.⁣
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Athletic Greens is offering Doctor’s Farmacy listeners a full year supply of their Vitamin D3/K2 Liquid Formula free with your first purchase, plus 5 free travel packs. Just go to athleticgreens.com/hyman to take advantage of this great offer.⁣
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In this modern world we place too much value on staying busy and deprioritizing sleep, which is why Dr. Hyman created his first ever Master Class. It guides you through the most important steps to getting better sleep, starting today. Get free access to Dr. Hyman’s Sleep Master Class at drhyman.com/sleep. ⁣

[@heathergrahame9647]

I have an intolerance to doctors who think that what a person eats has nothing to do with their health ... which essentially means I'm allergic to the entire medical profession!

[@QUINTUSMAXIMUS]

My GI has no idea about histamine intolerance. A lot of doctors don't know. I found out my myself doing my own research.

[@nurulizati6954]

@@QUINTUSMAXIMUS same and imagine try to explain it to my family that just thought it's not that serious

[@ronburgundy5778]

Same, at least 5 doctors I saw said it was all in my head, amazing how I feel better since working with a naturopath. Some doctors are terrible

[@mrmanq9517]

Doctors tend to be so ARROGANT yet they dont know sh*t....Ive been healing myself 😌 Leaky gut= L Glutamine (higher than recommended dose) Chew food thoroughly Digestive enzymes

[@Sunmoonstars976]

It's shocking. They can't even spend a decent amount of time to talk to you to get to the bottom of why you're feeling ill. They make a diagnosis and prescribe pills. Then they will have you running back and forth to monitor your symptoms or adjust medications. It's such a big business.

[@sheilasoule2774]

My son has been suffering, basically a recluse, unable to eat almost anything. He’s only 23. We’ve spent thousands of dollars for an IBS diagnosis. Yet he’s no better. He’s gotten to the point where he hates being hungry, hates his life. I’ve been praying so hard & he just “stumbled across” the idea of histamine sensitivity. It checks all the boxes. For the first time in years he has hope.

[@milenashubas6306]

Hi Sheila, just wondering how your son is doing? Any updates?

[@sheilasoule2774]

@@milenashubas6306 Hi Milena! Thanks for asking! He’s eating lots more foods than before but he’s still super cautious. He’s added berries, different lunchmeat, bell peppers, onions, garlic… it’s very encouraging!

[@biokeratingold3878]

@Sheila Soule: he needs magnesium. He has a brutal deficiency on cellular level. After 2 years of being in the same situation, I found out its all mineral depletion. Now I can eat more, thank God!

[@biokeratingold3878]

@@sheilasoule2774 look at my comment :)

[@marjorieharrington2513]

AMEN. So good when solutions are found. I also pray alot and know. I'm y alone, God is with us all. Praise You HEAVENLY FATHER.

[@annikadjurberg6762]

How demoralizing it is to be prescribed an SSRI and an anti-acid and metformin and told to eat more fiber and a good probiotic more fermented foods ; no wonder people are angry or not trusting with their medical provider.

[@SmooveBee1]

PS128

[@colleenclapper4477]

I'm in good tears right now. I went through undiagnosed and misdiagnosed for years to where I was seizuring 100x a day. I was finally diagnosed with Lyme just in time as they were treating me for ALS. I was born with rare congenital complications so have some of the top doctors in the world. Ive seen numerous specialists and nutritionists. Yet, no one has mentioned histamine intolerance. I just came across this information a few days ago and started the diet. The difference in me is crazy good already! Thank you so much for posting this information! Life changing!

[@lieselcoertze8430]

Look into heavy metal toxicity too

[@mdillinger1]

I hope you feel a million times better! Have they gotten your lyme healed? Have yet to meet any type of Doctor that takes insurance who acknowledges Lyme or lyme coinfections let alone long term lyme and how to heal.

[@brianbrady3455]

My girlfriend is 65 and develops a scratchy throat when she eats certain foods that create histamine. I give her 500mg TUDCA and in minutes symptoms disappear.

[@tendr247]

I can only eat fresh thawed meat. NO LEFT OVERS. I’m now going carnivore to get away from all the histamine veggies and fruits...also get off tea and coffee, chocolate. If you’re having a flair up...get somewhere cold. I use ice wherever I itch or a rash. I do take Benadryl only about once a week. Cool showers help. Also look out for oxalates. I avoid anything processed. Go as organic as possible. Plants make me ill. I live on grass fed beef, organic butter, pork, cage free eggs, cage free chicken. Meat is ok but not left over meat. Lots of clean water.

[@tendr247]

Avoid all flour and nuts.

[@evelynburley6106]

I lived with histamine problems for 10 yrs hives on my scalp went to 7 drs .. I knew it was food but I ate healthy they said I was to old for food allergy (62) so I took 8 day vacation ate totally different foods.. my hives were gone in 5 days.. so I came home looked up histamine and have been able to control my hives ever since.: tomatoes spinach and strawberries are my triggers..I’m 81 now ..

[@frankporter6169]

Great analysis.

[@crazydaizy915]

Wow...better late than never!! So glad you got it figured out, who would have thought such healthy foods would cause this problem.

[@LS030]

The doctors are to old to not know anything that helps patients.

[@w1975b]

@@crazydaizy915 technically, plants should NOT be considered food for humans. We are adapted so that we CAN eat them if no animal foods are around and we won't be killed right away (by most, some plants are more deadly when not processed correctly - poke sallet, red kidney beans and other beans, plus more), but plants don't want to be eaten (evidenced by the antinutrients that they contain, since they can't fight or run away).

[@mjfitness-personaltraining]

@Evelyn Burley, I have the same situation as u. About my scalp! Can u please tell me what medical exams I have to make to find the problem??? Thanks

[@cynthiacools-lartigue5297]

My only criticism is that I wish Dr Hyman would have allowed Dr LePine a chance to answer this questions....like when he asked about what foods to eat....

[@dianalove1576]

So frustrating!!

[@rothschildianum]

It is a genetic...He likes to talk and needs to lead in any conversation. But to be honest, I do not think he is annoying.

[@maritesfernandez4143]

@@rothschildianum Honestly, I find it so annoying. Sudden interruption loses my thought and excitement for the topic.

[@CindymeCindy]

I think he does an amazing job at interviewing.

[@loreneboone]

@@CindymeCindy Sounds like the opinion of a teenager female swooning over her older infatuation. So silly.

[@thefairyqueen369]

I love both of your energy and honesty for your patients! You are a pretty rare species so I am so very grateful to have stumbled upon your podcast! A huge thank you for your work!👍👏🙂

[@lisameyer7757]

This is SOOO PROFOUND! You are describing what I have been going through for close to 60 years. I describe my reaction to my "mysterious symptoms," as living like a monk... This histamine intolerance could very well be what has caused these symptoms/ in mty head problems... not just with me, but with most of my family members who have been called depressed and overly sensitive. UGH!!!

[@AG-qc1ob]

My husband had an oral allergy for over 15 years, he couldn't eat any fresh fruit and vegetables without throwing up. I mentioned this to a gastroenterologist I was seeing and he said ask him to try a good probiotic. So went online and found an article about this topic, histamine intolerance. Sounded really familiar because he has really bad seasonal allergies too. The article suggested using a probiotic with three specific strains of bacteria. Found a product that fit the bill and after a month or two of using it, he finally found the courage to eat an orange. It worked! He hasn't looked back since then. For anyone with this problem it might be worth trying probiotics. Will look for the article if anyone is interested in this topic.

[@bcgogue3239]

Hi. I am very interested in the article so kindly send if you can. Thank you!

[@AG-qc1ob]

@@bcgogue3239 the probiotics he uses has these strains. L. reuteri, L. casei, and L. bulgaricus. I’ve linked the article above. I hope this helps someone else. Good luck!

[@AG-qc1ob]

@@bcgogue3239 seems link was removed. look for “The Gut Flora-Food Allergies Connection” by Chris Kresser.

[@nanstevenson25]

I am interested

[@sarahgee4399]

Kindly share the name of supplement please your husband.is using.

[@karend.9218]

14:00 foods with high histamines, 22:00 supplements such as quercetin and nettles.

[@elliechapin182]

How much do you take of both. Thank you

[@Music-gw4qf]

Thank you

[@susiemiller2621]

An oral DAO enzyme will enable you to convert, break down, and clear histamine easily through stool and urine! Just like a diabetic needs insulin because they can not control their sugar spikes naturally.

[@priyanshusharma9416]

​@@susiemiller2621 from where do i buy dao supplements ( i live in India ) also can you suggest me some good brands for dao supplements

[@darciisabella]

Grass-fed beef kidney has natural DAO enzymes which allows histamine foods to digest. I take 6 capsules of beef kidney a day and have no more histamine symptoms.

[@dinbx917]

I am glad you are finally articulating with histamine sufferers have known for many, many years. This was so helpful!

[@lizzymcfire3199]

I have had and seen all of the ‘ologist’ and I’ve learned so much more from listening to the both of you than I have had seeing all of my specialists. I thank god I stumbled across this video, thank you for speaking on this. Very enlightening and an abundance of knowledge for us all!

[@helenmallaburnhashimotosNT]

This was great, thank you! I lost count of how many times I was told it was all in my head and offered antidepressants before each of my autoimmune diagnosis. Changing my diet, lifestyle & studying nutrition have really turned my health and life around. It's a shame that info like this isn't more readily taught.

[@carolynhamilton9728]

Hi, I am fighting off Lyme Disease from a tick bite nine years ago. I'm watching this, but not all the way through ~ (I wanted to write you fi⁰⁹rst, while listening) I'm curious if you are feeling better now? If not, have you ever been tested (the correct way) ? Just wanted to check in with you and your symptoms. I hope you are doing fine 😊

[@crazydaizy915]

Docs famous line when they don't know what's wrong. I had undiagnosed autoimmune disease in my 20's and doctor told me I was depressed and literally handed me a 2 week sample of Prozac and told me to make a follow up appt. I was furious and insisted that she do at the very least a full panel and 3 days later I was diagnosed with hypothyroidism.

[@ftturner6873]

I am sorry to hear that, but good thing is you are on the right path. Good Luck to you !

[@evelynburley6106]

@@carolynhamilton9728 I’m doing good just learned how to deal with it.. thx for caring

[@evelynburley6106]

So many older people have histamine allergy and have to suffer but try to tell most that changing their diet would solve so many skin issues they just keep eating and drinking junk foods..

[@marliesyanke4580]

Bingo, so glad someone is explaining this. I have suffered with it for years without help from any doctor.

[@alexl2519]

Two amazing doctors brilliantly covering histamin Intolerance... what a treat. Thank you both for being humble and smart. We need a whole system biology approach to medicine, medical schools and Pharma.

[@stellarsyd]

THANK YOU , ALL I CAN DO IS CRY …TO HEAR ACTUAL DOCTORS TALK THIS WAY ABOUT NUTRITION…Also you guys have a growth mindset and allow your practice to change with the research

[@alexd1121]

Dr Hyman is great but as often I wish there were more talk about solutions and less talk about the problem.

[@lindyn4]

It's a start at least they care and love their jobs making us aware of things it's so hard to find doctors like this I really have given up on doctors for problems like these but makes me happy to see that some doctors go the extra mile to diagnose and not brush you off as fine

[@kikamix1]

Agree

[@MoPoppins]

And risk losing a POTENTIAL CUSTOMER? This podcast is essentially an infomercial.

[@tanyaj8036]

He pretty much gives you all the worst high histamine foods, different diagnostic tests you can take, possible causes as well as pharma medicines and natural medicines that treat it. What more do you want? He is all about personalized medicine so if you want more than what he gives in this podcast why not see a practitioner? This is so informative, I can’t believe people are complaining honestly

[@Melissa_412]

@@tanyaj8036 I agree. Finding this was wonderful. I have delayed pressure urticaria and I had to pretty much find the diagnosis myself before presenting to a dermatologist to confirm it. My pcp had no idea what DPU was. I will for sure be looking for a functional medicine doctor in my area thanks to these videos.

[@adriannayugovich5033]

I have it from lyme disease! So happy to hear two doctors so educated on lyme!! I had to learn this on my own. ❤️

[@nancyinthegarden3160]

Thank you to both of you for your candid info on this very important topic. I’ve been suffering as well as my son with many allergies. Seasonal and foods. I’ve bc better with Vitamin C, while having a bout of diarrhea since Feb. I began Vit C for exhaustion and I need to take my health back. I don’t get enough Vitamins and am feeling better with these additional items to give back my endurance. I was Exhausted from Covid and had to seek my own corrections to help me improve my stamina. So tired of depression being thrown at all of us if we’re tired. I have hypothyroidism and Drs. Won’t address it. I’m healing myself now. Thank you again. When you want to do but can’t, that’s definitely NOT depression. Depression is the definition of feeling weighted down. It’s the body’s way of making us stop what we’re doing and take care of our physical to fix the mental. In struggled for 10 years and no med fixed it. Drs don’t get to the bottom of the problem just put a band aide on it and send us home

[@stevendehoyos2999]

THANK YOU. I also have dermatographia and suffer from histamine problems. This has helped me so much and I hope I can find a practitioner who listens and really wants to help patients like us who are brushed off.

[@josephinelai4638]

These two amazing doctors spoke out exactly what I am suffering and was misdiagnosed!

[@kyrstonbell1101]

I am going to listen to y’all again and take notes. You have brought me to tears soo many times just listening and the suffering I have been going through. I have too many symptoms on the daily and I’m getting to where I can’t deal anymore and trying to be healthy but nothing ever changes and I’m lost

[@keithhaken172]

I’ve been studying what these guys are talking about for years, and these 2 are “spot on” 🤙 thanks guys 👨‍⚕️

[@kyrstonbell1101]

The best conversation I think I have ever heard in my life!

[@sonchy99]

I have chronic dermography, and for the first time in my life I actually got some relevant information & it makes so much sense.

[@drylander3024114]

Thank you for using good microphones ,you and your guest are clear and understandable.

[@opedromagico]

that makes all the difference, indeed!

[@p.c.h.6721]

Well, 55 here, suffering since I was 24 years old, but it was all in my head, psychosomatic, my father would scream “stop complaining and don’t be so lazy!” Finally they said, it’s Chronic Fatigue Syndrome, too much suffering, I’ve thought of suicide a few times. At least someone understands, thank you

[@jeanettehansen4852]

I hope this new information gives you hope and help. ❤

[@PeaceIsYeshua]

@@PC, I’m so sorry you were misunderstood. People who don’t experience it can have an impossible time understanding. That can be so hard. 😔

[@greggonzalez859]

🙏🙏🙏

[@Bazza5000]

And it's the fault of your parents' genetics, and they attack you for having their genetics. And modern diets have made us worse.

[@sailuvijl6621]

I am in same boat Noone believes me 😢

[@beckiwildeman600]

I found this video so amazing that I had to listen to it a second time. I do think you have solved my problems and I am excited to watch to see if my GA goes away with addressing the issues you have raised here. I have been on probiotics for almost 3 weeks to treat my intestinal issues. I am sure I will be back to this video in the future just to refresh my mind to keep to the memory. I will say it was many years ago I pulled myself from the medical system because I seen the system to toxic. Since then I have been learning and searching for answers to my health on my own. In July 2020 I had the gastric intestinal issues start this has been a long haul but with the internet I have been able to limit the time that I suffer from those problems and have now set to healing that. I do believe Functional Medicine is the New future of medicine. Thank you both for being so fantastic.

[@caseyglenar7268]

Thank you for being a pioneer in the field of functional medicine and continuing to enlighten us about it. This sounds like something that I might have as a lot of foods that I eat (even the “good” food) can cause distress in one way or another. I suffer from random attacks from rash breakouts to huge hives that the cause has been idiopathic in nature. Throughout the years I have discovered, on my own, some of the causes, like wearing pierced earrings has caused my lips to swell but only 1/2 of a lip at a time and in different sections. So weird! Food and water temperature differences are also culprits. I had a breakout of lesions that sounded like ones mentioned in your video. These lesions were like scabs that you couldn’t pick off and lasted over a year. Most are gone now but I still have one on my shoulder I recently noticed that it becomes aggravated and itchy depending on what I eat. I wish I could afford to make an appointment to see you as I live in a town near your practice in Lenox but at least I will have more awareness of how the food I eat affects me. I have been on a health journey for a few years now and have made some progress and have had some set backs but watching you and other pioneers in the field has made my journey somewhat easier. This video in particular was most helpful. Thanks again for being brave enough to go forward while you were being mocked and dismissed. PS I used to work at the Ranch at the Back Spa Desk and in the women’s locker room.

[@greenleavesofsummer9673]

I guess it’s true after all, “All disease begins in the gut” -Hippocrates

[@colinesquire2480]

🤔

[@theresageiger584]

Yes it's true very very true I didn't know that I didn't know that

[@cristinscarlett9721]

Thank you so much for this! I was diagnosed with a histamine intolerance at 17 from an allergist at Mayo Clinic. They didn’t give me much direction for managing it and most doctors I’ve gone to since don’t know much about it

[@HeySenthil]

Look up pitta diet in ayurveda. It is easy. There are great literature in Ayurveda and then experiment with your foods from that list.

[@robertamurphy1124]

My son struggles with issues..mental and physical. His last psychologist prescribed an antihistamine. He never explained why. So glad you did.

[@weshendrikx9754]

Did it help?

[@Sundazs]

Dr. Hyman dominated the conversation. It would be great if you give your guests more opportunities to share their knowledge instead of constantly interjecting.

[@thoughtfulpro371]

He always does this 😂

[@soniahuman3690]

I agree, he's so annoying, feel like just shut up and let your guest speak, that's why they're there.

[@8brightside8]

Yes! And this problem has been mentioned numerous times on nearly all of Hyman's videos. I wish he would pay attention to the comments. It's ridiculous. He actually spoke MORE THAN HIS GUEST EXPERT.

[@starfly7]

Agreed. He's annoying. I skip over him whenever he speaks.

[@PINKSTONES6]

@@starfly7 if we all unsubscribe for a week... maybe he will read what we are writing!

[@2tennhills]

Thank you for opening the door to new possibilities for lingering conditions.

[@tammib27]

You guys are making me tear up. I've suspected I have Lyme disease for several years but my previous N.P. just did the standard test and talked me out of the expensive one. In fact, she got me thinking it was all in my head and put me on antidepressants. As a child I would break out in hives while doing laps in PE class. Back then no one really knew about allergies and thought people were making excuses to get out of gym. I'm hypermobil, been diagnosed with fibro, definitely have a fuzzy brain and go through bouts of fatigue. Now I know why I love doing water fasts for weeks at a time - I feel so much better not eating! These moments are tiny glimpses at what normal feels like. Thank you so much!

[@catherinemalcolm8125]

I hope you have found a diet that suits your needs now x

[@katb8709]

I'm trying double bergamot early Grey tea for the many benefits. Stupid question, can I do herbal teas if fasting for lengthy amounts of time?

[@wildlifegardenssydney7492]

please take care of yourself and please don’t do water fasts for weeks. Anorexia can come on quickly and kills slowly.

[@lukeskywalkerlucasfilm]

My story totally same!!! Professional Gaslighting from doctors and family.

[@mercyk2672]

@@katb8709 tea is not good for you if you're histamine intolerant. Also nightshade vegetables and fruits will trigger your symptoms. Maybe bone broth would be a better option. I've learnt so much about food triggers from dealing with this all my life 😫

[@amber305]

Great topic. I would like to hear more from the guest and a little less interrupting from the host. Dr. LePine would start to answer a question only to be sidelined and not finish his response. You can tell they both care about people and the subject. Thank you!

[@fereshtehamrollahi9980]

I'm an internist and I enjoyed your discussion so much. Thanks

[@annikadjurberg6762]

I love your guest in this show ; he is definetly on point in his knowledge . I wish we could hear more from him .

[@brendae]

Just saw your video and you are right on. After almost thirty years of suffering and like so many told it was all in my head my new allergist ordered enzyme testing and my tryptase was 15.4! I have now been diagnosed with MCAS and guess what it wasn’t in my head! Working on a low histamine diet and a doctor who is more familiar with MCAS. Just taking the H1 and H2 blockers has relieved my horrible anxiety and depression. I am so amazed! Thank you for your knowledge and following through with research and sharing!!!

[@totalwreckranch3370]

This was amazing information! I’m so glad that you two are delving into functional medicine! Thank you for information that’s just informative and makes me personally want to dig deeper and talk with my physician to see if he is open to this type of diagnostics and treatment.

[@reginawalsh3430]

You mentioned Professor Olle Johansonn, he is amazing, I would love to see him on your podcast.

[@0791mia]

I’m SO glad I this video was recommended to me. I have two daughters with chronic pain AND most of the other symptoms you mention. And years of finding no answers. I think you just may have helped us find one! Where can we learn about financial assistance? This stuff has taken it’s toll on their ability to work. One has insurance. The other doesn’t. They need help yesterday!

[@jons2447]

I hate to tell you this but; AFAIK 'functional medicine' isn't covered by insurance. Usually you have to pay 'cash up front', & it ain't cheap. But it is probably worth it to get better.

[@davidorawe3931]

Unfortunately, the stuff these doctors tell you to do often involves a LOT of money. Ultimately, one has to figure out how to do this stuff themselves, as far as possible. How are your daughters?

[@lovesdogs8616]

Thank you for all the great informative, for those of us who are chronically “off”, its great to have solid info for a resource.

[@jessicamichels5091]

Mold Toxicity is real too. Your living environment is so vital. The book Toxic. Neil Nathan MD, is one of the most interesting books I have ever read.

[@kathymyers7279]

Right. But after 30 years of RUNNING FROM IT , living in a car, searching for a home one after another, I’ve come to the conclusion that you CANT GET AWAY FROM IT.

[@FaCiSmFTW]

@@kathymyers7279 interesting yeah its everywhere even outside. And half of all buildings have water damage. Do you have CIRS? Have you discovered anything about how to help your body tolerate the environment better? Sometimes I think people focus too much on the environment and not enough on the body's resilliance to deal with an unavoidable toxic environment. When you see some people who are remarkably healthy in this toxic world without even trying it makes me curious

[@bernadettec2681]

@@kathymyers7279 Move to Vegas, they have new homes and its so dry there, mold is almost non existant

[@kristymarie6065]

How do you get rid of the mold?

[@jessicamichels5091]

The book talks about professional removal. But if it's truly effecting you that much....you move out.

[@maryamsukaynah559]

This is so informative. Thank you for being so clear abt disease and remedies. This was the exact way the indigenous medicine doctors healed their patients by taking them seriously as individuals. I loved your joke abt which half of learning medicine is wrong!

[@IlIKRATOSIlI]

This podcast makes me want to become a functional practitioner.

[@skyejacques]

Please follow your life path. We need as many healers living on purpose. Overcome your obstacles 🙏🏾👽👊🏽😊💓

[@tovah2276]

Functional Neurology for me! What’s stopping us?? I’m JUST getting healthy again and my brain is coming back so that’s my goal! YOU CAN DO IT!! (If I can, YOU REALLY CAN!! And WILL!♥️ Skyejacques is correct, we need ALL the Healers we can get on this planet or we won’t have a planet to heal!)

[@lindaclairesartori]

Good. Do it.

[@GCT1990]

I believe everyone should have a functional or neuropathy doctor no question. Unfortunately it costs more to be healthy. But functional doctors/neuropathic doctors are what modern doctors wish they were and I mean that. All doctors come into the field to help people, the problem is they get into a environment set up to screw not only doctors over such as the money they owe not to mention the finances needed T o keep a business open is ridiculous causing a secondary reaction of charging more, but it often injures the patient... Unfortunately now the doctors are stuck in this broken field set up against everyone. But functional doctors realized this and broke free... Started their own practices and actually aim to get to the root where as modern docs focus on treating the symptoms

[@adriswest5875]

0

[@emer6447]

Fantastic conversation, so interesting & informative. Love this wholesome nature of care in functional medicine approach. Thanku both!

[@charlottescalera5498]

Dr. Ben Lynch is a great resource for Histamine related issues.

[@susiemiller2621]

Yes! and a dirty DAO (balances POWERFUL histamine) is only ONE, (particularly nasty when broken) of 7 detox pathway genes better known as your digestive tract which not only digests nutrition, but also drives your immune system and is directed by your thyroid. MTHFR is another common one. Most who have one busted one will have others. Unlucky have 4 or more. An MD will say if you cannot methylate, you cannot live. THEY are WRONG. Directly tied to neurotransmitter issues as well.... off the rails Hello with CNS problems from B12 and Folate deficiency. MTHFR people need methylated B12 which is found in primarily in whole foods . Enrichments in processed foods are synthetics a compromised MTHFR metabolism cannot process. So you may show high B12 in blood yet still be grossly deficient in body. That fubars your entire metabolism. Messes with your iron, which can go toxic. (Hemochromatosis) Now your blood cannot carry enough oxygen the right way, and you eventually oxidize too much Iron. That can lead to a lot of nasty health shit including cancer. Ben Lynch book Dirty Genes and The end of Alzheimer's by Dale Bredensen.... all you need to understand your body and heal it.

[@yotersmitt]

I have a loved one who has major issues with histamine intolerance. Thank you for this vid.

[@LaneCodeRedCarnivore]

Look into Vitamin C . It really helps alot for me !

[@caroline61804]

@@LaneCodeRedCarnivore yes vit c is needed to break down histaminw

[@idahohoosier8989]

50 years ago, I had a dr tell me I had a serious histamine issue. No other follow up or direction other than to avoid certain foods. I'm going to guess it was because that many years ago. Wow, great show! Julie

[@mcpujol]

I would like to thank Dr. Hyman for putting out so much valuable information through his channel. I have struggled with this condition (that I didn't even know existed) for decades and finally I am finding answers, forever grateful Doctors 🙏

[@zohrasiddiqi4729]

Hyman

[@transformativemedicine7217]

I've been studying histamine intolerance for years now (I have gene variations that mean I make very little of the di-amine oxidase enzyme, sadly). You've taught me some things I didn't know, so thank you both very much. Great to hear colleagues who talk so clearly and simply about a complex subject.

[@alc1212]

What genetic condition causes low diamine oxidase enzyme production.? In curious to get tested. Thanks

[@ludo7102]

​@@alc1212same here, would love to know the answer

[@maartje3262]

What do you eat

[@lerylin]

Love it. Very informative. Great guest!!

[@jinaoneill328]

I have followed this disorder for years I was diagnosed with fibromyalgia when I was 19 years old and I have so many of the problems that you have said over the years I have learned through process of elimination what I can and cannot eat my life has been quite challenging up to this point however I am grateful that I have come across this video this is the most informative video that puts the most amount of information out there that I have found in a very long time thank you so very much for all of the work that you guys put into putting this video together

[@Flapperjaw]

This is why I follow Dr. Mark Hyman.....he's been " ahead of the curve" including the rest of the medical community , for years....

[@marcyoliver4020]

I'm very surprised you've not done an episode on oxalates! I think this is more commen than anyone realizes! Lowering my intake reduced 90 % of my symptoms...muscle aches, sleeplessness, eczema, rashes, fatigue etc.

[@unapologeticallyme7664]

And lectins

[@incognito137]

Yes! Also, salicylates.

[@marjorieharrington2513]

What are Oxalates ???? Can you please explain...

[@marjorieharrington2513]

What are Oxalates ????

[@celestevillegas6679]

Calcium oxalate is one, not sure if there are others. Found in spinach, chard. Can cause kidney stones and other problems.

[@AnthonyGarcia-be8ib]

I wish I had a doctor to diagnosed me long ago and now I happened to find out on my own today on this video!

[@verorsosa100]

Do it.

[@danab4337]

I'm Soooooo happy Dr Mentioned the Lyme Disease connection. Lyme is either the root or affected by so many chronic immune illnesses all or in Part.

[@thesecretlifeofwonderwoman]

Many years ago I went for allergy testing and was told that I have a histamine allergy. I had NO idea that was even a thing! The frustrating part is that the doctor gave me absolutely NO information on what that would mean for me and how I would need to care for myself with that allergy. Thank you for making this video! I just hope I haven't done too much damage in the years since my diagnosis. Thank you for this!

[@emilymoontarot8642]

same here and no doctors since seem to have heard of it. Crazy that some of the descriptions people are writing here I could have written myself.

[@bailey2777]

I recently heard Doctors do not study nutrition in school 🤯 But they learn alot about pharmacology 🙄😡 Very upsetting 😩🤔Better to go to a nutritionist 😢sad to know doctors don't recommend healthy food and even deny how important it is 😢

[@bailey2777]

@@woodymoto2326 Dr. Berg is a Scientologist who abused his son, so I will pass. Thanks 👍

[@salihaouchen790]

​@@bailey2777😢

[@Vi_k_torija]

Could you share how the information in this video has improved your life?

[@opedromagico]

Just got the book "The Disease Delusion", thanks for the recommendation!

[@MarthaHogan]

Dr Hyman. Please let your expert guest talk more. Thank you for presenting these topics.

[@starfly7]

he doesn't listen to the hundreds of comments asking the same

[@pattyahern839]

I know it can be distracting .If u listen carefully .Dr. Hyman, he elaborates with critical keys & info.On the remarks the other physician is explaining !! I learn so much from him !!

[@deborahmorrison6092]

Yes, Please let them talk!

[@ggbice]

I continue to revisit to read the new comments; all of value. The saying "you are what you eat" is unequivocally true.

[@neerukhurana4507]

You are what u can digest

[@galactikbutterfly]

Great content ! Mark is on the cutting edge of true healing care we are all individuals I predict that the nutrition profession will become more important than most common medicine ….

[@trisharnott7846]

Thank heavens for KZbin and channels like this. I suddenly developed hives a few weeks ago but worked out that my keto/weight loss diet was nearly all high in histamines. Haven't quite got to no hives yet but at least I knew where to start.

[@Victoria0987]

Dr Hyman, I have been listening to you for so many years and you are such a gift to all of us. Thank you so much for helping all of us more than you even know. Thank you Thank you Thank you ❤

[@brookcodyprice]

Love this info! Amazing! Why is this the first time I'm hearing about this!?

[@alexhowley9834]

Ive had hive outbreaks since 15, including one that could have ended my life. I break out in hot, stinging, itchy raised welts when i get severely stressed, anxious or change temperatures (like running in the cold). Its never been diagnosed properly and used to take Allegra every day for like 5 years. I still havent figured it out but i love listening to mark hymann and his guests bc its dives so deep into ROOT CAUSES

[@lenoredavi6137]

I had dermatographia for years, angry red welts anywhere my skin was scratched.... my body fluids were so acidic that l would have burn marks on my face for days if l cried or had a drippy nose. I paid hundreds for blood tests and was shocked to discover how many foods l was allergic to. I had nearly all of the symptoms described on this video.... Lucky for me, in my late 50's an acupuncturist diagnosed me with histamine intolerance. Life changing. I had wasted thousands of dollars on doctors who gave me advice that made it much worse. Even after my gene test l was still being given incorrect information. Glad to see that there are some people around who recognise and treat this condition. Keep up the good work.

[@maddyL1234]

I have this problem and would have loved to hear the guest more. Dr Hyman likes to interrupt, please don't. Otherwise, you've got a great show. Was very beneficial to me in particular. Chromalin and Xantx sounds amazing thank you.

[@marjorieharrington2513]

What are chromatin and Xanax for in this situation???? Does it relate to allergies l am aware that Xanax helps my anxiety no side affects. Never heard of the other one. I must have missed it. So much info to absorb and not knowing the meaning of All the terminology . Am in my 80s & still looking & trying to find answers. But only homophatic way , not taking pills. We wouldn't have near the problems if they didn't alter our food & cause so many people problems, but ,alas what would the pharma do , go broke. Yes I need to improve my attitude ( Dr.) But they do suck!!

[@jeanniecampbell1374]

I wish they could have put up some of these complicated medical words so I could see them ...so interesting !

[@VScorp7]

I am so grateful for this video and all of the wonderful information your videos offer. I am a reiki master and create videos in support of clients with MCAS. This information makes me feel like creating more support. I so appreciate all you do. Thank you 🙏🏻

[@catrinagriffin6141]

This is so good! Glad KZbin suggested this video❤

[@RanDom-bk8tt]

Omgosh! That was incredibly helpful!! My allergist stopped at giving me medications and a forever elimination diet prescription. I don’t blame him but it still baffling to me that this is the standard. Your podcast really helped me learn more about what I can possibly do to further find out what is causing my symptoms. Thank you and stay well.

[@karentait7806]

Thank ,this was so good informative and I’ve learnt lots today so thank you much appreciate your time .

[@karenweidauer6861]

This is amazing. I’m sure that this is a big part of my problem. Thank you so much Dr. Hyman 😊❤

[@isla4953]

This video is wonderful! The best source of this issue I have found. It was a girl on Tiktok talking about how she developed Crones disease due to histamine intolerance that made me wonder due to many of the symptoms of DAO enzyme issues... I believe this is the cause of my mother's, my own and my son's severe reactions to foods, chemicals etc. My mother suffers from EMF reactions. We thought she was possibly imagining 😞

[@lynnann137]

Excellent interview. My functional medicine doctor suspected that many of my symptoms were related to a histamine intolerance so he added DAO to my daily supplements and it sure has made a difference. I have been dealing with leaky gut due to celiac disease, SIBO, and Candida, so high histamine foods cause me mast cell activation syndrome. My condition has caused many symptoms as mentioned in this podcast, ie: headaches, sinusitis, nausea, anxiety which leads to insomnia, chronic fatigue, joint pain, itchy eyes, multiple food sensitivities, and just feeling miserable. I am on a limited diet trying to stick with protein, vegetables and healthy fats, but I had added a lot of prebiotic foods to help heal my gut but so many of these healthy foods create too much histamine in my body. Adding DAO has helped me digest and has taken away so many of my histamine symptoms. This is a great interview to share because most people, including doctors, are clueless about the role of histamine in health problems. Thank you for sharing this.

[@Life.in.london132]

I have same situation right now all the problems i have but i feel that every food (except gluten and dairy as im not taking it) is attacking on my nervous system and eyes,feel brain fog headaches heaviness in head & eyes sever dizziness even i cant walk with dizziness. Drowsiness.. fatigue.. 😢 Is ít histamines problem? Can you plz share your diet and medicines😢😢brands and dosages of medicines?

[@vickyredfern1800]

Hi what is dao please? x

[@Life.in.london132]

@@vickyredfern1800 Diamine oxidase (DAO) is an enzyme that your body makes to break down histamine from foods. If your body doesn't produce enough DAO, you may have diamine oxidase deficiency.

[@lpeek56]

What is DAO?

[@brendao6576]

Love your podcasts and they are really helping me to learn about health issues many physicians poo poo. I found a great functional medicine doctor/acupuncturist who has helped me so much with my autoimmune and your podcasts have solidified my faith in what path he is directing me to a healthier me.

[@quail349]

I was listening while working, and then 19:57 - Ehler's! Well that's me! I so rarely hear it mentioned, and I really appreciate you two's knowledge on what's so commonly ignored or unknown. It's hard to find much solid information regarding everything I'm working through, and you guys have mentioned quite a bit. Thank you for that!

[@SabrinaRene4565]

I have dermatogaphia and some other skin sensitivities I’ve never understood. thanks for this video 👍🏽

[@scotielass]

I'm suffering. Been this way in a chronic state since 1984. It's debilitating. I happen to stumble on this video today searching for anything and everything to find the reason for the issues that plague me. Going to your website now. Hoping to find any information/help that might start a process to my recovery.

[@odafjm5]

I love these sessions! I learn so much from them! I've never heard about this topic before and it sounds like a category that I might fit into. 🤔

[@robertbrewer1152]

Very informative I’ve suffered from food intolerance for a very long time. I removed wheat and helped tremendously changed my life but I can’t seem to figured out the rest. I suffer from migraines my whole life although better I’m still dealing with it. Like an allergic reaction daily to something. Can really only eat I meal a day but I’ve been trying to eat an egg in the morning and small salad or Greek yogurt for lunch but just bloats me and cant have normal bowel unless I only eat once a day except I’m hypoglycemic I’m assuming due to my gut issues. So thankful you guys are working this out although I don’t have doctors near me who understand food as medicine it gives me the understanding to work it out myself in time. You guys are hero’s to us who are suffering through this alone.

[@sisunit07]

It's very frustrating to know I have this issue, but there is no one around my area who cares about this stuff, and I can't afford to travel to find good help. I feel like my life is just slipping through the cracks before my eyes, and my hands are tied. I am following every bit of the advice you give in your videos to the best of my financial abilities, and it does help to a degree. Thank you for that.

[@lisanilsson3269]

Hello, I came across a specialist nutritionist who you can get an appointment online-Leanne Hopkinson in Austalia! Also look up Happy without histamines website

[@claudettesechler149]

Wow! I have been waiting for a podcast on histamines and the body! In the 70’s I had interstitial cystitis and saw so many doctors and scoped and I finally found out about histamines and diet..took a while but eradicated it. Thank you for always hitting these great topics!

[@stephanieadams237]

I have this too and would be interested in learning more about what you did.

[@claudettesechler149]

The first thing was to eradicate sugar and ate very low glycemic..lots of protein and everything green..then after getting my insulin level down, I started adding starch like sweet potato..on my plate that was really like dessert..rice that had been cooked and chilled, but never more than 15 grms. Or 1/3 cup of carbs per meal. So my plate is half veges, 1/4 protein and a 1/4 starch..fruit only a 1/3 cup and never with a meal and wonderful fats! Olive oil, grass fed butter, ghee, grated 100% chocolate on my coffee..nothing processed..full fat Greek yogurt and intermittent fasting! Once you get clean see what your body can handle..I know what tricks mine off and that is processed, sugar laden food. So sorry for the rant, and sure Hope it helps!

[@sammysal8252]

@@claudettesechler149 thank you that really helps x

[@claudettesechler149]

I changed my eating habits. I stopped eating all processed foods, alcohol. Most importantly I did food combining. If I ate fruit I would make sure it was never near a meal. My plate was protein, veggies steamed and raw, lots of olive oil, apple cider vinegar and now 1/3 cup of starch and I made sure that is what I ate last and made it like a dessert because I eradicated sugar. For supplements omega 3, methylated B, Magnesium, zinc carnosine, and when flare ups UVA ursi tea. I am an avid excerciser as well and it’s important to keep your muscles toned as you age. Get rid of all processed foods, especially flour products unless you are able to get European made products..then if you want start adding in to what you can tolerate. Fats, protein and lots of veggies and now a great glass of wine with dinner!

[@rosemurray831]

Thank you so much for educating those of us that are looking for answers and true healing....

[@charlesbarkley1340]

Thank you so much for this video, for years I suffered with horrible food related migraines, about 4 years, put me into a depression, tried everything and doctors were quick to turn me away with simple explanations of migraines. Finally a dietician pointed out to me that I may be suffering a histamine intolerance, changed my life, keep spreading the message guys!!

[@sailuvijl6621]

R u better now

[@mylittleredadventurebooks8621]

Thank you for this. Lyme and toxic mold exposure can be the root cause of MCAS. Great info. Keep more like this coming.

[@lauraaulenbacher934]

I have had 5-6 issues of histamine flares in a four year period of time. What I have found to work is to go low on high histamine foods for about two weeks, take two quercitin, on B6, and Betaine HCL to tolerance with each meal. Keep up the quercitin and Betaine and you may not have too many more issues with this.

[@arcaneyesarcaneyes3709]

Hello, Now you can eat normally high histamine foods such as strawberry, tomatoes... ?

[@denisemartin3603]

What were your stomach issues? Why HCL? Was this per Dr?

[@chirpsta4286]

This was simply excellent! Have had Lyme disease and have plenty of the symptoms you’ve described. I’d have never suspected a link. I’m going to start by trying quercetin and perhaps keeping my cell phone off of the bed when I sleep. I’ll save this clip as well to listen to again. Can not thank you both enough!!!!

[@michellea9857]

Will just turning off the wifi on your cell phone work do you think? I keep my Ipad near my bed and wonder if this is ok if I just turn my wifi off?

[@justdawndb]

65 here, lyme from 89. Don't even bother with regular drs anymore, you two however are in an entirely different league, species..THANK YOU! This was really interesting & informative.

[@annag.4571]

Thank you for talking about histamine intolerance, there are very few doctors who speak about that. I was also misdiagnosed for about twenty years and suffering of unknown recurring symptoms until some specialist discovered I had histamine intolerance. General physician and even gastroenterologists are not aware of this condition and do not know anything about that. Thank you very much for addressing this issue!!!

[@sarahthomson8183]

What symptoms did you have?

[@annag.4571]

@@sarahthomson8183 Body aches, general discomfort, muscle pain especially in the upper back, extreme tiredness, lack of concentration, brain fog, rapid heartbeat, low blood pressure, insomnia, intestinal problems, food allergies, digestion problems, nausea, headaches, etc.

[@MusiC14545]

@@annag.4571 How did u fix it??

[@germanshepherdmom1143]

I have histamine intolerance too. My symptoms are heart palpitations , elevated anxiety and insomnia.

[@annag.4571]

@@MusiC14545 I take H1 antihistamines, Quercentin, vitamin c, melatonin and gaba at night, and have a restrictive diet. I also try to sleep enough. The symptoms are still there but they are weaker and I feel better now.

[@knmylesmovementwellness3778]

Would love more focus and discussion on MCAS.

[@marilialevacov2939]

Me too!

[@michaelday5605]

I had to diagnose myself with MCAS because my doctor is oblivious. I made a playlist with the best videos I could find describing how to diagnose and treat it : kzbin.info/aero/PLuMzmJohtr1WjOzOqTU0V-2mNVtkf3XWg

[@marilynbara6330]

This is great. Second time I’m watching this episode, will probably watch it a third time. Like what other people have said, I went to seven different doctors with my weird and extremely painful, but intermittent symptoms. They all literally shrugged their shoulders. I’m healthy, my blood work numbers are excellent, they said I was fine, we don’t know what you have. Anyway … I finally figured out it’s a histamine issue, made changes that helped, then found a truly amazing nutritionist who has helped MONUMENTALLY! You should have her on your show, she’s a local gem, she really saved my life. No exaggeration. But it’s also KZbin and shows like this one that have saved my life. Thank you. Many, Many Thanks!

[@BMusicShousha]

Can you elaborate on what it is exactly that helped you out?

[@karencampbell9358]

Very interesting! This may not only help me but my son and daughter. Thank you!!!

[@suebradley4829]

Thank you. I’m 5 years recovering from Babesiosis, mycoplasma pneumonaie, chronic EBV, Bartonella, fibromyalgia etc....undiagnosed Lyme disease. Double vision is my big issue now, have risk lenses. Itchy skin lately, have had 4 squamous cell skin cancers removed from my face and arms during this time, I’m now going to research histamine thanks to this podcast

[@makikiss87]

I have the same diagnosies,can you tell me what protocol you had,which meds and supplements?

[@abutterfly7975]

What did u take to get rid of fibromyalgia?

[@unapologeticallyme7664]

I'm so happy for you that you have recovered I am definitely ill... Would you mind sharing what you've done?

[@mistyblue511]

Years ago I was diagnosed with Mastocytosis. It just came on one day and for one year my life was miserable, and then it disappeared. Listening to this talk, it makes sense now why certain foods effect me the way the do... it's histamine intolerance. It's awful too.

[@cecisdiary]

Did it just go away naturally? Just got diagnosed…it's the worst.

[@KH-xc5fq]

Take DAO enzyme. It digests histamine. Prayin Jesus heal you!

[@cecisdiary]

@@wk8000 For mastocytosis? It's very different, depending on what kind you have, I believe there are multiple. But essentialy histamine reactions in many ways from skin rashes to allergic reactions. I don't have it anymore tho :)

[@cathybrown4102]

I also had mastocytosis once unexpectedly in 2006. Never knew what triggered it but a massive dose of cortisone got rid of it but made me very sick. I do have other symptoms of histamine intolerance (I.e. sinusitis, asthma, insomnia, bowel issues and periodic hives). I am going to try eliminating foods high in histamines and hope it works

[@maartje3262]

What did you do

[@annamarianaka8052]

Thank you so much! Amazing, very informative discussion.

[@MelodyMaker218]

Wow, this was such a great video, thank you!

[@mumsthwd]

I have h-EDS and a histamine issue. It was mild until I got sick with "C". I now have long/post "C" because of the major increase of histamine being produced in my body. I have been to so many doctors over the years. I finally gave up. I have had to become my own doctor. Thank goodness for the internet. I so wish that other doctors would watch videos like these.

[@jgo304]

There is a direct connection, I also bet you have MTHFR & DAO gene mutations. Ask me how I know 😊 have you had your plasma histamine level checked??

[@NerdyGirlLiveLove]

This. Same ling covid made it 10x more

[@maartje3262]

​@@jgo304so ehat to do

[@user-fe7lf8ei3u]

Long Covid

[@matthewkepley5631]

@@NerdyGirlLiveLovejust learning about this, my symptoms became severe post covid infection in Dec 2020. Been suffering on and off since. I knew I wasn’t crazy, covid messed me up.