JAK-STAT Signaling Pathway

JAK STAT Signaling Pathway Lesson: Ligands, Receptors, and Importance in Disease.
Hey guys! In this lesson, you will learn the JAK STAT signaling pathway, the ligands that activate the pathway, the cell surface receptors involved in the pathway, and the functions of JAK and STAT in the pathway. You will also learn about how the JAK-STAT signaling pathway is involved in different types of cancer and polycythemia vera.
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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
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Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.
I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :) And please don't hesitate to send me any messages if you need any help - I will try my best to be here to help you guys :)
Thanks for watching! If you found this video helpful, please like and subscribe!
JJ

[@franciscosantos3437]

Before Janus Kinase, JAK would stand as: "Just Another Kinase"

[@josefsterner6000]

@Andrew Wilks Cooooool!!!

[@CosmicCitiZenOfficial]

J silent 😂

[@sanjaisrao484]

@@CosmicCitiZenOfficial cool

[@miriamerick5637]

your explanation made a very complex biochemical process a little easier to digest. Thank you!

[@avnishah6823]

wonderful explanation - easy to understand this complicated pathway!

[@victoriab7375]

Might be a silly question but is there a difference between receptor tyrosine kinases and tyrosine kinase-associated receptors? Or are they the same thing? Thank you

[@hadrielvalentino]

I know this is a long shot but you can watch Dr Najeebs lecture on these pathways

[@danielgladish2502]

4:53 you mention STAT homodimers and heterodimers then focus only on homodimers. Is it only the homodimers that enter the nucleus and work as transcription factors? Or can the heterodimers do this as well? Thank you for the fantastic video!

[@jaym9846]

Is the JAK-Stat Pathway related to FGF21?

[@rraww]

very good explanation.. Thank you..!✌️💞

[@AhmedNoureddineHelal]

Thank you. Very good presentation and explanation.

[@btudrus]

As far as I can remember there is a cross-activation between the insulin and the insulin-pathway and the JAK/STAT.

[@dr.sammasud7401]

Lovely way to explain. Thanks

[@andreaferrell1441]

Hey JJ, you probably get this a lot so I hope you don't my asking, I was wondering why you stopped making JJBartleyMusic videos, and if you have any intentions on continuing to make more videos in the future? Your piano tutorials were immensely helpful, and are greatly missed!

[@gamaltaher9714]

Thanks

[@sanjaisrao484]

Thank you

[@zahid8096]

You re my hero bro

[@bernardojunqueira2392]

Loved the T and T tip :)

[@Biya101]

Thank you!

[@user-fm1yh5vc1o]

ありがとうございました

[@MuhammadJunaidAshraf]

What about growth hormone?

[@escueladekrebs7195]

EXCELENT!

[@thuytrangngo516]

thank you, this video is easy to understand :)

[@demekeeligo64]

thank you best

[@1x1x1is1]

Thanks dude

[@MJ-wc6nm]

So helpful, thankyou.

[@sakshisood7108]

Thank u

[@user-hv5dd5so1f]

good

[@rafnaegels8913]

You forgot the TLR4

[@johnstillman2935]

do I detect just a hint of Irish accent in your voice ?

[@nadhirahbaharin.]

I was thinking the same thing!

[@cherrypeaches4906]

he's canadian, the aboot should have given that awaay lol

[@Dmhiz]

That's Scottish ​@@cherrypeaches4906

[@philbertkatende757]

❤️