Tom Benson - Mitochondrial Transplantation Solves Mitochondrial Aging - EARD 2022

Tom Benson is CEO and Founder of Mitrix. He is a serial entrepreneur and scientist who founded 4 successful software, hardware, and science startups including Timepoint Corporation, Readybot, and Scott Systems. He has deep experience in acquisitions, negotiations, finance, project management, and marketing with a deep tech focus.
He was also a manager at the Linac Coherent Light Source (LCLS) facility at Stanford Linear Accelerator National Laboratory, where he gained interest in the imaging of mitochondria via x-ray crystallography and Cryo-EM. This work led him to explore the recent fundamental changes in scientific understanding of cellular energetics and mitochondrial systems of the body.
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#EARD2022 #Lifespan #SENS #TomBenson #MitochondrialTransplantation #MitochondrialAging

[@thewineholics]

Finally some practical progress

[@Film.1-x5i]

Hello, your followers from Iraq, what is your work?

[@Rafas216]

Qual o seu trabalho?

[@blackpoolbootz2790]

Wow never knew this was possible

[@anaabendroth3460]

Those of us who are suffering from Fluoroquinolone Adverse Effects, effects that have damaged our mitochondria - long term - are VERY interested in this research. I, for one, would be more than willing to be a test subject!! Any updates?? LOTS OF US WANT TO KNOW!

[@FullSend27]

Incredible, this therapy makes so much sense!

[@carolfoox2792]

Fantastic

[@BrentNally]

Tom gave a fantastic presentation! I know Tom has been very passionate about the potential that young mitochondrial transplantation can have so it’s exciting to see this progress! Bravo!

[@tombenson5957]

Thanks Brent. Good to see your work in longevity as well!

[@BrentNally]

@@tombenson5957 thanks

[@scott8393]

Hi Brent imagine seeing you here.

[@ppowell1212]

Great job

[@SirTenenbaum]

Very cool to hear updates on this.

[@tyanite1]

Truly fascinating. Thank you.

[@rhyothemisprinceps1617]

Really exciting work, very encouraging. On various forums over the years I've posted the idea of creating synthetic mitochondria that could 'infect' patient cells & replace the native mitochondria - never got any replies.

[@houndofzoltan]

They should be trying this on pigs and dogs this year.

[@martinmatte7597]

wow just wow.

[@houndofzoltan]

the three Rs... reduce, reuse, recycle... aren't the platelet mitochondria being reused rather than recycled? In fact isn't that the point, the platelet is being recycled, but it's a waste to break up and remake the mitochondria so just reuse them? I'm sure he means reuse when he's talking, I just feel reuse is more precise...

[@andreasstuermer4946]

Wondering if you can see a reversal of the Horvath clock (DNA Methylation)

[@VitosVibe]

How to get new Mitochondrias?😁

[@nozhki-busha]

You grow fresh young mitochondria in a bioreactor tank then transfer them over to the patient. Mitochondria do not trigger an immune response and cells readily take them up when they find them in the bloodstream. In principle all you would have to do is inject a bunch of mitos into the bloodstream and the cells would absorb them.

[@Rafas216]

Pesquise sobre ubiquinol, pqq e principalmente sobre o ciclo circadiano satchin panda. No futuro teremos outras fontes.

[@immortalityIMT]

26 kb, pretty large, can they be utilized as a vector?

[@benji-5796]

Hi Tom, would this work for fluroquinalone toxicity? Where the mitochondria have been damaged.

[@newdata]

can argue that with extra mito, the animal is burning the candle at both end , and end up living half the life span. and likely the mice with extra mitochondrial live shorter life.

[@aysgl2666]

how do you select healthy mitochondria before growing them in the bioreactor?

[@dxbmodalitychannel1042]

Great work Tom, any plans to test with Emulate "organ on chip" technology? thanks

[@tombenson5957]

We'll look at it!

[@larsnystrom6698]

This suprisingly enough seems to be real! At least, the mechanism is as described, so it could work. Looking forward to some animal trials. Well worth watching this video and check out the research on the mechanisms.

[@MrChristian331]

Looking forward to HUMAN trials. When is this stuff going to be available for humans?? I think I need a re-charge now...

[@charlessavoie2367]

Crown loyalist Wall Street Episcopalians will not allow small people to have any such boost. Eugenics is the order of the day. People in Tuxedo Park New York and at Jupiter Island Florida can get it due to a very high price tag.

[@ConfirmedCynic]

Most proteins that appear in mitochondria are coded in the genomic DNA. Even if a fresh mitochondrion is introduced that houses a healthy complement of proteins, how long will that last in a less than healthy cell?

[@rmsoft]

Mitochondria is different in different organs.

[@andreasstuermer4946]

The nucleus has better DNA repair

[@esakpiyarji1834]

Hi my son age 11 having mitochondria disorder is it cureable can you please advise will be thankful from india mumbai

[@tombenson5957]

We hope someday this is possible, but there is a lot of work still to do. Good luck to you and very best hopes for your son.

[@starraider25]

So where can I buy some lab-grown fresh young mitochondria?

[@tombenson5957]

We're working on it! :)

[@JacobAFarmer]

@@tombenson5957 What happens when you mix mitochondria from a different maternal lineage? Does that work or does that trigger an immune response? Should we be harvesting cells from young family members with common female lineage?

[@tombenson5957]

@@JacobAFarmer You are on the right track!

[@bertmoore4092]

Will this procedure change the DNA of your original mitochondria?

[@andreasstuermer4946]

Nope, but replace a part of them

[@haludan111]

Honestly, I got a triple dose of stem cells 6 years ago, and I feel amazing. I'm almost 50, no wrinkles, the only sign of my age is a dad bod, and my beard is white. I shave that thing off, and I look anywhere between 30 and 45. Stem cells seem to be the key, at least if my experience is anything to go by.

[@ddutton4716]

How did you get this? If you were in a RCT how do you know for sure which arm you were in?

[@rmsoft]

Yes, do it. And they do good business with you.

[@tombenson5957]

Hi Daniel, stem cells are indeed a great therapy. Note that one of the things that stem cells do when you get them (according to the latest research) is - they donate mitochondria to your cells! So the stem cells in addiition to other things, are mitochondrial delivery vehicles! See 5:40 in the presentation.

[@scott8393]

What is unethical about teenagers donating mitochondria? I have some young cousins...

[@tombenson5957]

I asked my nephews. They laughed at me.

[@scott8393]

@@tombenson5957 what's involved with the donation? Is it painful? I donate blood plasma to complete strangers, I don't laugh at the people who need plasma products.

[@JacobAFarmer]

It seems obvious. Find some young kids with common maternal lineage. Offer them $100.