Must-Have Over 45: Top 3 Daily Supplements Everyone Should Be Taking for Longevity

[@WellnessMessiah]

September 2024 Update: I NO longer Recommend CoQ10 over 45 (but over 65). Get new research updates and practical routines to save you money and time here: wellnessmessiah.com/longevity Get this Gift When You Subscribe (it's FREE): ⁠www.wellnessmessiah.com/gift

[@raelin8388]

Hi Rimon..one suggestion as an added bonus would be more detailed description of your actual workout out protocol\techiques to maintain muscle mass.. As we know.. next to diet and sleep..it's top pillar of heath and longevity 🙏🤗

[@johnbarryyallagher1128]

You gave a throw away comment that niacinamide does boost nad. Why and justify that statement. After all Time + booster has niacinamide omongst others

[@V_Dgt]

Thnx for great videos! The question: when to start? What supplements to take at different ages?

[@moniryousefian8782]

Hi Rimon, Thank you so much for your Great videos very helpful and informative 👍❤😊 Could you please share which brand of niacin are you taking?! Greatly appreciated 🙏

[@jedwards1792]

1 Coq10 2 k2 3 nad boosting with MNM, NR, niacin Bonus: glucosamine

[@AquaFrost777]

It's NMN. MnM is a candy, lol.

[@chasingshangrila]

@@AquaFrost777😂😂😂 I died laughing

[@saintjabroni]

@@chasingshangrila😂😂😂

[@nebojsa1976]

@@AquaFrost777 You don't understand. Chances are MNM probably has more benefits than NMN, just sheep don't understand.

[@leelunk8235]

​@@AquaFrost777YES THE CANDY IS WAY CHEAPER😂

[@barbarablanco5767]

Next time don’t have such a loud music in the background so we can hear you more clearly

[@gregariousguru]

Bless your heart Karen

[@sarahostrinsky4595]

LOL

[@WellnessMessiah]

Ok i will try you're right

[@shawndaspille7259]

Exactly what I came to say - and I never comment on videos! The info is great but it’s really hard to listen to with the loud music! Actually, I’m not convinced that we need music at all. Thanks for being open to input.

[@seekfactsnotfiction9056]

@@WellnessMessiahno one needs Damon music

[@gobsmacked230]

Rimon is my favorite... good presentations...and I don't mind the music😊.

[@joegoodwill5313]

Thanks for a very well produced and helpful video. Just one little thing - the music is UNBEARABLE. Please don't add a noisy and distracting sound track. ESPECIALLY if your target viewers are seniors. A lot of us find it really hard to hear and absorb content if there is loud music competing. I wanted to get all the information but I was forced to stop because the music was making me crazy.

[@bernibeckmann9753]

music makes vitamin infomercial sound like clown world, good for American public looking for added value

[@WellnessMessiah]

Thank you @@bernibeckmann9753

[@WellnessMessiah]

Ok I will try. I can't resist sometimes

[@fidelogos7098]

The music isn't needed at all. If you must have it, turn the volume down or get a more serene soundtrack.

[@bernibeckmann9753]

@@fidelogos7098 welcome to the jingle, health information is party time

[@GuadalupeCook-v5r]

We need more of your Expertize. Continue sharing, what We humans need for our health n long ivity n happiness. God bless you

[@WellnessMessiah]

Thank you. I think I need to do more content for 65+. there is a lot of suffering that age we can and should prevent. It's not a profitable niche so researchers and experts leave them alone. I'm still thinking what can be done here

[@colinmaharaj]

2:30 Yes I did meet an elderly gentleman once, who claim to be very weak all the time. I asked him if he uses a statin and he said yes, so I told him to get a supplement called coq10, it's the most expensive supplement you can get, and he agreed, that was a Saturday morning . Monday morning around 6:00am (I don't wake that early) he called me and told me he had a ton of energy after taking the supplement and thanked me profusely.

[@WellnessMessiah]

Cool anecdote, thanks for sharing

[@WellnessMessiah]

Happy New Year, happy holiday, lots of love in your direction♥

[@meungawa]

Great content. I have two suggestions: 1) the token music is way too noisy and constant. People won’t want to come back as much or at all so I’d bag it or greatly reduce the volume and only in a few places. 2) be more succinct overall. People are busy and there are always too many other options. Thank you for the valuable information!

[@LizGrantComedy]

I concur. Thank you for the videos @wellnessmessiah

[@naijaman6639]

I am pleased to see your channel is growing gradually. Please keep up the good work.

[@WellnessMessiah]

Thank you, I'm pleased to meet you here again

[@renasafarova1672]

@@WellnessMessiah can I take resveratrol 1000 mg, coenzym q10, 200 mg, niacin b3 and NMN together every day for 2 month? Thank you

[@anonanonm]

Can you make a top 10 video about supplements that a senior (80 years old) must take?

[@WellnessMessiah]

yes I need to make 65+ video. which will cover all ages following

[@mohammadharoun3839]

Thanks Useful & intensified information

[@dd1maher]

Most of all I enjoyed the music... I couldn't hear most of the content. I hope it is fixed in your future videos as I think you have a great channel and I just subscribed.

[@robertsitt3217]

Hey Ramon. This was great but could you make the music louder? It’s to quiet in the background

[@jeannineosorio6566]

Hello Rimon! Thank you for this great info on Niacin, CoQ10 and K2! I was wondering which brand could you suggest for Niacin? I am 70 and do not take any medication and exercise during the week. Thank you!

[@WellnessMessiah]

Hi Jean, the truth is niacin is so cheap (and easily traceable by having a bit of flush) that I think it doesn't matter. Any company will do I currently take a capsule that has low filler but I must take it with food/bit of olive oil/avocado otherwise I will have a flush because of the quick absorption of the capsule. I also try 250mg sustain release, I'm doing an experiment on myself, yet to be published - still unsure on its effect. Google 250mg extended release if you want to try it too. There is only one I've found on the market.

[@slimturnpike]

Is it true you have to experience the flush to benefit from niacin? Is time release niacin OK?

[@shakunvashisht342]

@@WellnessMessiah CAN I TAKE THE SUPPLEMENTS YOU SUGGESTED HERE ALONG WITH MAGNESIUM GLYCINATE, VIT B12, VIT D3...{THESE 3 SUPPLEMENTS I AM TAKING REGULARLY]

[@stephanygates6491]

PQQ with CQ10 facilitates glymphatic cleansing while you sleep. Not vs - together.

[@LifeAccordingtoRobandDidi]

really? omg this is great info considering i just got my medical results stating i need lymphatic drainage and i happened to see Dr. Mercola talking about these two supps and now i see your comment...no coincidence here

[@63viet]

Thank you for your post.

[@WellnessMessiah]

Happy New Year, happy holiday, a lots of love in your direction♥

[@RajTravelogues]

your excel sheet looks awesome.. sharing it would help tons of people

[@jazzkardasz8576]

Screenshot with mobile

[@danielcfalves9976]

Very good !!!

[@WellnessMessiah]

Happy New Year, happy holiday, a lots of love in your direction♥

[@semaaral2498]

Super informative another video. Thank you & Continue to pray for her progressive🙏🌟🌱💯

[@WellnessMessiah]

Thank you :)

[@trench01]

Did i sum it up right? Obviously best to see the video for full details since it says a lot that I did not state but this is just a reminder on some points. CoQ10: - What it does: Helps generate energy in cells, supports heart health, and has antioxidant properties. - Why we need it: As we age, our cells create less energy and more toxins and damage, leading to aging. Levels of CoQ10 can also decrease due to stress, toxins, and medications like statins. - Dosage: Take 100-200mg/day if over 45-60, or higher if taking cholesterol-lowering drugs. - Food sources: Fatty fish such as salmon and tuna, organ meats like beef liver, and whole grains. - Warning: CoQ10 may interact with certain medications, including blood-thinning and blood pressure-lowering drugs. PQQ: - What it does: Promotes new mitochondria, and the dosage was listed as 20-40mg and may have anti-inflammatory effects. - Why we need it: Our bodies produce less PQQ as we age, which can affect mitochondrial function and overall health. - Dosage: Typical doses vary from 20-40mg/day. (500mg for recovery split up 3 times in the day) - Food sources: Kiwi, parsley, green peppers, and fermented soy products like natto. - Warning: As usual do not over do it. Vitamin K2: - What it does: Helps with calcium utilization and bone formation, and may reduce the risk of heart disease. - Why we need it: Vitamin K2 is not as well-known as other vitamins, and many people are lacking in this nutrient. It is especially important for bone health and heart health. - Dosage: Most studies use dosages between 45-360mcg/day. - Food sources: Cheese, eggs, butter, liver, and fermented soy products like natto. - Warning: People taking blood-thinning medication should consult with a healthcare professional before taking vitamin K2 supplements. Niacin: - What it does: Helps with energy metabolism, cholesterol management, and may improve insulin sensitivity. - Why we need it: Niacin is important for several aspects of health, and deficiencies can lead to a range of health problems. - Dosage: Low doses of 150-400mg/day can reduce inflammation and may improve insulin sensitivity. High doses can cause liver damage and inflammation. - Food sources: Beef liver, chicken breast, turkey, peanuts, and mushrooms. - Warning: High doses of niacin may cause flushing, itching, and an increase in liver enzymes. Glucosamine: - What it does: Supports joint health and may reduce inflammation. - Why we need it: Glucosamine is an important nutrient for joint health, and may be beneficial for people with osteoarthritis or joint pain. - Dosage: For joint health, Glucosamine sulphatethe recommended dose is 1,500mg/ twice a day. - Food sources: Glucosamine is not naturally found in foods, but it can be derived from the shells of shellfish. - Warning: People with shellfish allergies may have an allergic reaction to glucosamine supplements.

[@soez_strg6166]

Great post, thanks!

[@adisyoye]

@@soez_strg6166 thanks!!

[@ozarkcyn1]

Thank you for summing it up!

[@chidude]

PQQ helps create new mitochondria, and the dosage was listed as 20-40mg. Glucosamine sulphate dosage was corrected to 1500mg twice per day at 18:15 in the video.

[@ty-lim]

Thank you, you're very helpful.

[@aab512]

Thanks for such great well researched content It would be of great help if you can share your opinions on anti aging drugs/ lifestyle for early to mid 30s Better start early since we already have so much knowledge right now with us

[@Anna-zy4ys]

good questions

[@WellnessMessiah]

hi anna Happy New Year, happy holiday, lots of love in your direction♥

[@kristihook5713]

Dear Ramon, your information is so very helpful thank you. Your computer screen shows a graph of vitamins,effects etc. Is there a place where we might download this screen information? Perhaps a file or small e book? Thank you we need all the help we can get staying mentally, physically well. May your generosity return many fold. Sincerely from Tucson Arizona

[@jazzkardasz8576]

Screenshot on mobile

[@UNKLELUKE86]

I appreciate the positive effects I experience when taking niacin at 500mg. I'm talking about the flush.

[@WellnessMessiah]

Yes, it makes me tipsy at 500mg fast release (not sustain release). you probably know what i'm talking about, niacin on this level inhibits stress enzymes, reducing anxiety.

[@litterature-w7u]

high NAD+ levels also actually promote cancer cells!

[@The_Modern_Buddhist]

Great work, thank you ❤ 8:25 comment here saying “go to ???? It costs nothing” where was he recommending getting mnm from at an affordable price?

[@WellnessMessiah]

Hi I said "low dose niacin it costs nothing" sorry bad audio quality Aim for 50mg in large containers , should cost about 1 cent a capsule/tablet. P.s. if you can - subscribe 😉

[@The_Modern_Buddhist]

Aw that’s absolutely amazing thanks so much for explaining ❤

[@dhhavs]

Am gonna order these supplements right away, loving ur content jus xame across ur channel a few days ago. Whats ur latest take on using fisetin/quercetin as senolytics?? Do they work?? Have u made a vid on these which i could refer to?

[@walidoulondon8107]

I love your Chanel ❤

[@yohanonshine4664]

I would like to present the negative effects of coq10 .At half recommended dosage was experiencing lightheadedness after 3 days as a machine operator I threw it away realizing although it may be needed I already get enough from my diet.

[@andysgriff1965]

I bought some today 😊

[@marianaranjo1814]

Thanks a lot Rimon for your excellent work. Could you please clarify further on vitamin B3 type we should take? Not quite clear to me what difference between niacin and nicotinamida. I can't find niacin 50mg in the market but nicotinamida 50mg. Niacin dosis in the market are quite higher than 50mg. It would be appreciated if you could tell us what brand you take. Thank you very much!

[@WellnessMessiah]

niacinamide in low dose is good for longevity but you already get it from food and b vitamin complex. High doses inhibit sirtuins - 100% sure. So I would stick with niacin/nicotinic acid instead. Niacin is a name given to separate it from cigarettes' nicotine... not the same thing.

[@AquaFrost777]

@@WellnessMessiah Will Nicotinic acid produce flush the same as niacin? I can't even take Niacin doses of 25mg because the hives are so severe. It feels like and looks like an allergic reaction. The anxiety caused by the intense itching is too much.

[@musaire]

Excellent video! Can I ask which is the video used where David Sinclair talks at 8:45 about niacin - the title of the video, the channel, or the link please! I have used niacin myself for a long time now. Been taking every other day, and 1000mg - maybe lower can be used indeed. It's really important to concentrate on keeping the salvage pathway going by NAMPT enzyme running and NNMT enzyme not over-working :) - so we redirect niacinamide onto a new cycle.

[@richardramfire3971]

Watch his Joe rogan interview

[@AquaFrost777]

Great information, but the loud music volume makes it hard to hear the presented info.

[@WellnessMessiah]

Sorry, I stopped this music in future videos. my fault! Happy New Year, happy holiday, lots of love in your direction♥

[@AquaFrost777]

@@WellnessMessiah Thank you for being open to your followers suggestions. I like your presentations and will continue to watch.

[@samanthar6172]

Can you do an episode about berberine, please?

[@WellnessMessiah]

yeah I need to do more thorough research. very complicated molecule.Happy New Year, happy holiday, lots of love in your direction♥

[@mellkiades]

What about Magnesium and D3? Those are much more essential, why ignore them?

[@tablameister]

CoQ10, K2, NAD + Niacin

[@jlove8445]

If you total the amount of supplements we need to take to be “healthier” it’s up to about 30 capsules a day + Omega 3 Fish Oil, probiotics too.. it seems like a never ending list, are these now the only three? LOL

[@alvinayeo7102]

Hi Rimon. I like your videos but this one is very hard to go through with the distracting music

[@WellnessMessiah]

Ok will try to tone down in the future.

[@lukeclaydon6670]

Lovely 😊

[@WellnessMessiah]

Happy New Year, happy holiday, a lots of love in your direction♥

[@msplateaugal]

Should we consider taking NMN and low dose Niacin?

[@WellnessMessiah]

Yes, it should work better, I'm still not fully understand all the wide range of metabolism by NMN, so better to track your body

[@carmela6834]

Very interesting but get rid of that annoying music. Thank you

[@jillianzocher2733]

Hi Love your videos. At the 8.33 minute mark in this video it says' go to a sniping' in the subtitles and i can't hear that word and so I am unsure what he says - please ca you let me know.

[@paulevans2246]

Thanks. What vitamin brands do you recommend on why? I’m based in the uk

[@WellnessMessiah]

Check patreon.com/wellnessmessiah. Happy New Year, happy holiday, a lots of love in your direction♥

[@aaronsalmon1376]

Hi there. So If I was to take these, do I need to take, a multivitamin, fish oil, etc? I'm taking a few vitamins/supplements already, does taking these cover most of what you NEED, or should you still take others? Thank you.

[@gospelofthomas77thpearl22]

Have you looked into the NICHIDO product? It has been double blind tested & proves to be effective as a NAD booster.

[@WellnessMessiah]

No I haven't. I don't research/take skin care products at this point.

[@gospelofthomas77thpearl22]

@@WellnessMessiah it is actually a longevity supplement 👍🏼

[@falcon127]

MY DOCTOR NEVER TOLD ME THIS! MY PHARMA COMPANY NEVER TOLD ME THIS!!!

[@paulmtilley]

Thanks for this but the background music to loud and distracting :/

[@chirokathleen]

Did he say Niacinamide is not good to take? What form of niacin does he recommend

[@heatherhilderbrand7298]

What do you think of Dr Nichola Conlon and her research? A systems approach to NAD Restoration? And her NAD booster Nuchido Time?

[@jamesherried9269]

She claims that 150 mg of niacinamide daily is the most effective way to increase NAD levels. It's also the cheapest way.

[@Exodus26.13Pi]

From elite athlete to dying of obesity BACK to real health. Below is my life's work distilled. 🎉 Recovery: Inclined Sleep Therapy is free & an ancient practice CPAP Exercise: *Rebounder* proven in the 1970s as the most efficient exercise still. Unique health benefits. Food: Lean poultry, onions, & sweet potatoes replace unhealthy calories Dentist gum cleaning Supplements: Threonate magnesium, NAC, vit.D, creatine, taurine, *methylene blue-not with antidepressants* TENS for soreness & vagus nerve Their's more but this's most of it.

[@mccarthy4718]

Wasn't there a recent study about NAD and Brain cancer?

[@xjoy3920]

Why you didn't try niacinamide instead of naicn?

[@WellnessMessiah]

I explained at the end of the video Happy New Year, happy holiday, lots of love in your direction♥

[@gloriagolemboski4515]

I’m allergic to niacin. I mean really allergic in the emergency room. Would NMN also cause rashes and swelling where I needle shot.

[@MrZdrojek]

Nice video, so much knowledge, etc. What if the music is too loud and interferes with reception/understanding. You can please edit it and remove these pointless musical inserts???

[@WellnessMessiah]

Sorry, I stopped this music in future videos. my fault! Happy New Year, happy holiday, lots of love in your direction♥

[@Anna-zy4ys]

which are goid affordable brands for qualury q10

[@davidtempest7175]

Common sense approach to raising NAD. Going to copy your low dose strategy. Thanks for this info!!! Great video.

[@suzihazlove4979]

What was that. I can understand him. Oh I'll put captions. 😂

[@christopherellis2663]

It's ubiquitous in eukaryotes.( q10) K2, butter. ( NAD) niacin Berg ❌️ Sinclair ❎️

[@janconlie581]

I currently take 500 mg each NMN and resveratrol. I’ve been reading about GlyNAC. Have you investigated whether these supplements interact? I was considering Fisetin Mayo protocol also but I’m a little concerned that all of those combined may be overdoing it

[@joenisnapje712]

Resveratrol and Fisetin are both on the out. Watch dr Brad

[@ginadani9688]

Take TMG with nmn and resveratrol because derivate of b3 like nmn lower methylation and that is bad for genes involve in cancer. Start all from low dose.

[@ttttia4734]

I take NMN and glynac daily. They work together just fine. I take high dose NAC because I have lupus. NAC is like a wonder supplement. Google NAC and any disease/illness and you will find that NAC helps it.

[@ginadani9688]

@@ttttia4734 if you take dose of nmn over 200mg better take tmg equale dose👍👍👍

[@silver___]

Great video but the background music is too high and disturbing and I can't hear the speech properly.

[@WellnessMessiah]

Sorry, I stopped this music in future videos. my fault! Happy New Year, happy holiday, lots of love in your direction♥

[@Corteum]

What's beter....NMN or Niacin? ----- I think the obviousl solution is to just take both!

[@WellnessMessiah]

possibly yes. NMN is rather expensive in effective doses 1-2 gram, 200-300 mg of niacin csrs 5 bucks a month

[@Corteum]

@@WellnessMessiah What are people reporting with 1-2g doses of NMN? Does it have any acute effects?

[@ozarkcyn1]

Can you check out nichita Company that was started by Nikita Conlan? She said Mnm doesn't help the cause of low Nad which constantly decreases. Her supplement does address the cause. Dr. Mercola interviewed her.

[@MrCt40]

Can you recommend any other European companies who sell pure nmn apart from Do not age ? They are really expensive

[@WellnessMessiah]

Ideally is buying from many brands and pay third parties out of pocket. Maybe I will do it. For now, look for GMP, third-party testing, a brand that existed for 10 years or more (reputation)..and test your NAD levels after 14 days of usage.

[@DGFX64]

Great video, but it mentions “…a high quality CoQ10…”. How can the average person workout which products bought OTC are high quality and which are garbage?

[@jamesherried9269]

Many years ago, all CoQ10 was made in Japan. And I think it's probably still that way today. So it shouldn't matter what brand you take, if it's from a reputable, reliable company.

[@FightCollective]

Well thanks to these 'longevity' videos I've been taking NMN (and spent a small fortune on it) yet it doesn't even get a mention in this list???

[@aroonsarin8303]

There was a mention on NMN here. I Don't remember rimon ever making a video on NMN.😅

[@Akas410]

Which form of niacin? Niacin flush?

[@catiamadeiras6909]

Hello Rimon, you talk about Niacin... what is you opinion about Niacinamide? I am taking 500 mg of niacinanide but after seeing this video I wonder if I should starting Naicin instead.

[@jazzkardasz8576]

Google Dr. Abram Hoffer re niacin studies

[@DemetrioSahaquiel]

I’m 36, can I continue taking Coq10?

[@healthyfixes6357]

Sir what about Niacinamide 500mg Daily,if one take for boosting health and specially Skin looks.. kindly reply

[@carlsapartments8931]

There is no way I could get to 600mg of niacin, I get a flush at 50-100mg. A flush is not harmful as it just a very temporary dilation of blood vessels that goes away fairly quickly but it can uncomfortable and even alarming to someone that does not know what is happening.

[@sweetbon76]

I take Niacin right before bed. That way I don't notice the flush. I take 1 gram every day.

[@jazzkardasz8576]

Google Dr. Abram Hoffer ... Take an asprin initially ... The body adjusts very quickly to it normally...empty capsules into flask of drinking water and sip thru day

[@michaelcurtin2064]

The background music is very distracting, trying to listen

[@andriyurenov7215]

What about berberine and its ability to shrink plaques? From the latest research it seems it’s much more effective than any intervention, including statins

[@Battery-kf4vu]

What about N-acetylglucosamine? If one takes NAC, should he lower the amount of regular glucosamine?

[@WellnessMessiah]

I don't know this compound, only glucosamine sulfate, so I can't comment

[@rickrobbins580]

I took low dose niacin and it raised my homocysteine levels

[@vicfarago4091]

i passed out cold wilth 50 mg of niacin

[@peaceandlove5214]

Can you take them all together at once?

[@swimbait1]

NMN has been found to be very safe.

[@josephmarcello7481]

It takes an immense amount of unconsciousness not to realize how alienating your drowning music is in preventing the listener from understanding what's being said in the video. There is an intelligent folks out there in the world, and they don't need to be entertained with junk music while they're trying to find life saving information. Time to grow up!

[@sigma.m]

Is prolonged-release niacin better than regular niacin? Do both have the same impact in the liver?

[@WellnessMessiah]

Good question. As we speak, I'm checking 250mg sustain release, and there is even 100mg sustain release too. I'm just trying to find the best protocol on sustain release for longevity, I don't think this 500mg every day is best. For sure, you want to cycle sustain release (I need a video to explain why).

[@sigma.m]

@@WellnessMessiah what could be a negative effect of 500mg or more dose of niacin aside from its impact on liver and blood sugar?

[@ChuckleberrySoup]

@@sigma.m higher levels of Homocysteine in the blood

[@yenbacunata3430]

How can i buy those supplements without doctor to ptescribe that, i only read that here in your vedio.

[@alaneddy4575]

Hi Ramon. I just signed up for your project 120...got lots of ultiself upsells during the checkout which I took for now at least but got nothing from you that mentions a project 120 course. Where is it buddy? Is it built into the ultiself premium app or how do I see the course? It looks like your course is actually a yearly membership which is ok so long as it gives constant value and new information. Just a little concerned I didn't get an email from you regarding the course unless I'm misunderstanding something.

[@WellnessMessiah]

Hi Alan, just read it now. The login access is most likely in the spam folder. If you can't find it, the customer service is at [e-mail] let me know if they didn't treat you right. It may take them a few days to respond because of the new year. Lots of love, Rimon

[@alaneddy4575]

They sent me the link via email. Thanks Rimon. Love your work...your mum looks amazing. Keep up the good work.

[@yenbacunata3430]

Can we just get those vitamins from food especially that vitamin k2?

[@howiesfunware]

Rimon, do you still suggest on/off taking low dose Resveratrol?

[@cryptodeath854]

I think you’ you need to be more specific than to just say Niacin. Niacin, is an umbrella term for nicotinic acid, niacinamide, or nicotinamide. The two later (niacinamide & nicotinamide) are one in the same thing. Nicotinic acid gives you a flush. They are very different compounds. Nicotinamide or niacinamide are the main precursors for NAD. Video for reference. Flip to 43:40 kzbin.info/www/bejne/r5KUont3o8Srl8ksi=AjkJ0JDp3rj5HkRb

[@paulagibbs5525]

Thank you for this. Very helpful.

[@entropy0917]

For me even 25mg of niacin is very uncomfortable - hot flushing and can't wait for it to wear off. I tried just 13mg today and could feel it but no flush, but don't see the point. I tried the slow release awhile ago and did not like that either - too uncomfortable. So it's just a no-go supplement for me ...

[@sweetbon76]

I take it right before going to bed, then I don't notice the flush.

[@WellnessMessiah]

Yes, the goal is to stay healthy, not suffer more. Try taking 25mg with food and if it doesn't help, no need to suffer needlessly.

[@winsonlim4586]

what niacin wae usee? nicotinic acid or niacinamide?

[@MrCt40]

Ok so niacin ( low dose flush nicotinamide ) could be used in place of nmn for those who may not afford NMN ..?

[@chidude]

My take away is to take low dose niacin throughout the day as a more effective and less costly alternative than NMN for boosting NAD, but maybe also work in a bit of NMN to target boosting NAD in the nerves.

[@lapislazuli7876]

It is so confusing I have no idea what to do

[@chipdouglas3565]

Rimon, I emailed you through your available through the email address available here on You Tube, but never got any response. I don't know whether this is a misunderstanding or not. My question had to to with the above vid, where you advise CoQ10 as a must-have supplement. However, Dr. Brad Stanfield did a recent video, where he pretends the complete opposite about CoQ10. Now we got two experts, used to looking at the science and yet, come to two completely different opinions. One is looking at animal research and the other at human evidence ? How to reconcile the aforementioned discrepancy ? I was interested in your course, but not so much anymore at this point.

[@WellnessMessiah]

Hi Brad and I have different backgrounds. You will have to make your decisions who should you trust. I suggest watching my intro video where I shares some of my results to help you choose your path. Happy New Year, happy holiday, lots of love in your direction♥

[@LouisHansell]

Is niacinamide the same as niacin?

[@WellnessMessiah]

no. happy new year

[@davidwright4271]

I just don't know if it is safe to take niacin if taking statins (to treat high cholesterol) and blood thinners. My cardiologist did not like the idea.

[@WellnessMessiah]

always go with your doctor

[@jazzkardasz8576]

Google Dr Abram Hoffer ... Change to whole plant food diet plan ... No money ... Cardiologist Dr Esselstyn ... Will halt or reverse heart disease ... Science Dr. Greger .. many more

[@jazzkardasz8576]

Most doctors and surgeons have no expertise in diet and nutrition... Their training is only based on prescribing chemicals ...nothing on healing your body naturally

[@s18018]

Just to confirm, the "flushing" type of nicotinic acid is better for NAD production?

[@WellnessMessiah]

yes. but we don't need much and better to divide to small doses

[@timskolnik3819]

I had to turn this off because the music was just to much

[@dinomiles7999]

Bryan Johnson Blueprint, Ai will soon take the guess work out of it and all gurus and snake oil salesmen will soon be gone. Don't die. See you in 2500. Eyes mind heart and soul wide open . NO FEAR !

[@stephenthomson1435]

Can you re-edit this without the loud music?

[@musaire]

Yes I think if using lower than 500mg or even 1000mg nicotinic acid per day, it is okay to divide it. Other than that, if the doses are high (for some other reason than NAD+ - as in elderly using it for cholesterol for example), it is better to use all at once because it takes the amidation pathway in the liver if dividing it all over the day - the liver can amidate 40mg an hour or so, if I remember correctly. It is conjugated by glycine if used high amount at once. This applies to portions that don't get incorporated into NAD+. Hmm, but low dose divided, under 500-750mg a day may be indeed nice for NAD+ - I need to think about that - currently I am taking all at once because I dont mind flushing and counting the transient inflammation as having a hormetic effect.

[@musaire]

The main reason for me to take 1000mg at once is that I wanna trigger GPR109A receptors, known as niacin receptor (though niacin is not its natural agonist), gets activated by certain level of nicotinic acid only - yes we get receptors activated with smaller amount already but not all over the body and it can partly be confused with TRPV1 activation which makes the skin burn as with using chili pepper - nicotinic acid also activates TRPV1.

[@WellnessMessiah]

Yes you're correct, it's conjugated by glycine. It's good that you got it. Interestingly, TMG provides both removal parts for niacin (glycine) and niacinamide/NMN/NR (methyl). What worries me about the flush is the effect on prostaglandin 2 of the skin, which is clearly pro-inflammatory. But it is only in the skin. another benefit of separation is that niacin targets organs that consume NAD every 2-4 hours. so you feed the animal when it's hungry.

[@musaire]

@@WellnessMessiah Nice! I had been using nicotinic acid once a day because I was using 1000mg amount (it was useful in covid times but had suspicions for regular use) but now thinking about going 4x lower, mainly because I saw on Michael Lustgarten channel that his NAD was even too high with 600mg (measured in blood cells probably, so we don't know all organs but..) but his aging tests was revealing more aging - maybe the excess NAD is used for CD38 (so we'd need to inhibit that - with apigenin etc). We don't actually use much methyl groups on niacinamide methylation once we direct the niacinamide back to the NAMPT route and so to create NAD+ anew - that's the best scenario tbh - so with my bog doses I didn't care if I feed it new niacin constantly because ideally niacinamide gets recycled into NAD+ by NAMPT enzyme anyways. Inhibiting the excess NNMT enzyme (by EGCG and green tea for example) helps to keep the niacinamide flowing into NAD and also preserving methyl some groups. You surely know about most of it :) , so I am mostly writing for random readers that go by, that fasting and exercise also helps with NAMPT activation as do many supplements like rutin (which provides better slow-release quercetin as pure quercetin itself as if realeases itself during the pass through all intestines , keeping the levels nice in serum so liver enzymes don't overmetablize it as it does with quercetin), many solutions act on NAMPT via AMPK activation (incuding berberine I think but also resveratrol and lipoic acid etc). Anyway, yes, I am thinking of using less niacin now and work better on and search for how to activate the salvage pathway more actively, and more inhibition of CD38 and other inflammatory NAD-consumers in case of larger niacin doses. Sweating out excess niacinamide also important ;) because there is no methylation used. And yes, it comes out in sweat. Thats partly why physical training is nice as well as saunas. :) Anyway, enjoying the video! I like the info I got few days back hearing about how working out once per two weeks may be enough for muscle group, nice :D

[@duffusedward1326]

@@WellnessMessiah So DO we need to take TMG with niacin?

[@jazzkardasz8576]

Take an asprin after initially to combat the prickling and severe flushing if you are sensitive... Your body will adjust ... I prefer to empty the capsules into a bottle of water that I drink throughout the day with glutamine that repairs your muscles ... You cannot overdose... on niacin ... Google Dr. Abram Hoffer.... Must change to whole plant food diet plan ... No money ... Science Dr. Greger ... Cardiologist Dr. Esselstyn ... Many more ... Supplements are not enough plus weights plus HIT exercise

[@kohdorothy586]

There are so many brands of supplements in the market. How can I can assess I am buying from a correct supplier.

[@javadivawithdog]

CoQ10 is useless without DHEA and EPA. You just kind of skipped over that L-carnitine in the referenced migraine study 🙄

[@ozarkcyn1]

She also said you can't test NAD levels in a normal lab.

[@oolala53]

Honestly, I looked at the title, and then I looked at how long the video was and I’m skipping it. I’ve listen to so many hours and hours on your channel and others that I’m at the point where I just don’t feel like an afford the time. Maybe you could make shorter versions of some of these, and then refer us to the longer ones if we want more validity. You and a few others I tend to trust the judgment of so I would be willing to take a look even with shorter explanations.

[@paulcohen6727]

His videos are great to fall asleep to lol

[@DJdavefromlondon]

Hi . You said The body converts soft plaque to hard. K2 prevents this. Does this leave the plaque as soft = more dangerous than hard ?

[@WellnessMessiah]

yes, it will still be soft plaque which possibly could be removed by hdl. this is why k2 isn't the sole strategy here...and won't be bulletproof. still valuable as it does many other things

[@DJdavefromlondon]

Thanks. I realize K2 has other benefits but is it a strategy to purposely not take k2 in certain circumstances related to plaque ?

[@ceterisparibus210]

In my view, do not act for these supplements without getting confirmation from your own doctor. It depends on your age, gender, family history, weight, and your blood test results.

[@IamZZZH]

That would have been doable in an ideal world but the reality is most doctors have no knowledge whatsoever about any supplements or dosages or combinations..... its a sad reality.

[@WellnessMessiah]

yes correct. esp. drug interactions.