Do "Smart Drugs" Work?

[@neurotransmissions]

Just to lay this out there, taking the nootropics was not intended to be scientific in any way. Just one person taking these nootropics for just one day is terrible methodology and I began researching this topic before taking the nootropics, so bias was present. But I wanted to try them and thought you’d enjoy it too! Trust the science, not me!

[@TristanMorrow]

0:08 0:09 _If you've never heard the word before_ ...try looking at the Greek roots? The first part, nóos-the mind or reason. And, either trophikós-growth, or, tropikós-turning or changing. Gets you close enough to differentiate context. And if that was an unfamiliar approach to you, you will _definitely_ get _better_ results from _reading_ and _studying_ *more* than from dabbling with nootropics or anything else. (All after diet and sleep.)

[@silkwesir1444]

I don't know if that's what Tristan Morrow was getting at, but I think it is pronounced like "know-oh-tropics", not "new-tropics"

[@padpadangz9774]

I'm most interested in caffeine, could you explain the link between caffeine and iron levels dropping if you excessively consume caffeine?

[@restupido3691]

✌☺

[@crypticPk]

XD I was going say one day ain't enough lol.

[@MedlifeCrisis]

Wow this was a real tour de force, huge amount of research and information. I would love to achieve how slick your videos are. Before we first chatted way back when and I had just been a regular sub I assumed you were one of those fancy PBS shows! I didn't even realise some of these were being taken as nootropics, I've only really heard about modafinil and similar. Very interesting.

[@fasolashow550]

Wow didn't expect my favourite youtuber here, nice surprise❤

[@yellsabob]

As someone with attention problems, I've resorted to many different ways to try and get work done. Strangely enough I've found one of the most effective ways was...no sleep. 30 hours awake, 10 hours asleep. Used to run that a lot during uni. first 12 hours had the usual distractions issues. then 8 hours of fighting tiredness wanting to sleep. Then 10 blissful hours of feeling awake and focussed, if a little strained. Really the closest feeling to the actual nootropics I've taken, concerta, but with those pills there's no strain in the background, and memory is significantly improved. Above 30 hours gets damaging, with skin repair and digestion etc affected, above 50 hours hallucinations start, and above 80 simple subconscious functions like weight balancing while walking start to fail. 30 hour days (or 40 if you count nights) were manageable, basically sleeping every other day, but long term memory was severely affected after a few months. Not something I'd recommend... Caffeine provides energy, but not focus for me, same as energy drinks. But then I suppose instead of trying to enhance my brain, I'm trying to suppress thoughts and urges that stop me working, so the opposite of most people using Nootropics?

[@yellsabob]

also, I make coffee so bad that it's the shock and self-loathing that wakes you up before the caffeine hits.

[@Corporis]

Just wanted to point out to other viewers the amount of research that went into this one. Check out all those peer reviewed sources in the description!

[@mickmickymick6927]

0:52 'Immune boosting things that go in there' well I'm sold

[@keshavbx]

Great video! I personally like to combine my coffee + green tea as the caffeine & L-theanine work pretty well together. All in all though, you're right - sleep and exercise are the best ways to help you function at your best!

[@gloopsgloops]

Keshav Bhatt there was a study done that showed a synergistic effect than caffeine or green tea alone, so it’s not just placebo! Good stuff!

[@brionical2299]

Good to see Pyrocynical still uploading, thanks for the vid dawg

[@scootermom1791]

Caffeine also causes heartburn - or, at least, aggravates it if you're prone to heartburn. I have experienced this side effect myself. It also can give a person heart palpitations. Again, personal experience.

[@iwnl_vale]

Creatine takes some time to have an effect, and needs to be taken everyday.

[@mrlion9719]

Yeah thats the only supplement of the list that I take, so it made me question the quality of her info on the other ones. Plus she left out a lot of other common nootropics.

[@teresathomley3703]

Holy moly I thought the cat meowing was a little kid in the background!!

[@NarutoOrganisation13]

I know it's not the point of the video, but it's really cute how the cats are trying to be involved in the video. They can tell that Some Important Event With Talking is happening (especially at 3:55 with Bill), and they want to do the same things their humans are doing. 💕🐈

[@jessevillanova378]

Thank you lady. It was SO difficult to find nootropic vs placebo studies and everyone on youtube is a goddam shill. I've left so many angry comments today to "Doctors". Thanks I really appreciate the sources and the cats are very cute. Have a nice day.

[@Zeldur]

I only recently started drinking coffee but it's only 1 cup (the unit size) whenever I can't wake up quickly that morning. This is especially helpful on rainy days because I can't stay awake when it's raining. It's not the sound because I don't have to know it's raining to be sleepy.

[@neurotransmissions]

Hmm, maybe when it's raining it's just darker outside than normal? I know I have a hard time feeling motivated when it's super overcast.

[@Zeldur]

@@neurotransmissions Thanks for replying and I'm not sure. I've been tempted to try a full spectrum light to combat it.

[@AroundTheBlockAgain]

Barometric pressure can be a huge factor that a lot of us forget about, too! May you stay warm, well lit, and happy!

[@biohackshq4072]

Nootropics are legit depending on the ingredients, dosages and quality. Numerous studies confirm the positive effects of various nootropics on the brain and body.

[@rayweaver2069]

I have used Caffiene and L-Theanine together with inconsistent results, depending on when I take it and how sleep deprived I am at the time. But it definitely is different than just caffeine.

[@MrDangerousshark]

This is some top quality content! Great Job!

[@neurotransmissions]

Thanks so much! :)

[@tommywhite3545]

I love taking Flakka and go eat faces thinking I'm posessed!! (Being sarcastically.)

[@suetheblue9309]

Your channel is Fuego.

[@yup-2067]

When taking creatine you don't notice a difference in energy just that your muscles can work a little longer with out being in as much pain because of water retention that expands the muscles in question in your case biking your legs probly didn't feel like you did alot of work even though you probably bike a mile or more considering you look pretty fit. There is no real Neuro response from creatine as far as I've studied. There some suggestions that your extra water intake is very good for the body. Since most people don't drink enough water daily.

[@nicolaiveliki1409]

Engage yourself socially - shows people playing beer pong. I love yous guys! I like green tea, and yerba mate (Ilex Paraguariensis) which supposedly also prevents gout

[@XZenon]

On a very related note, can you do a video about adult neurogenesis and the recently (re)discovered drugs that supposedly promote it?

[@nicholasalonzo3499]

For a scientist she really does show some strong biases

[@kibrika]

I drink a lot of black tea. I've heard it has as much caffeine as coffee, but I'm not sure. I also feel like it's a needed pick-me-up if I'm sleepy or tired, but I too wonder if it's just the ritual and familiarity of the drink. I don't drink green tea because it's easier to make it taste bad if not prepared correctly compared to black tea. I might try to switch to green tea for the evenings.

[@neurotransmissions]

Tea leaves do have more caffeine than coffee beans, but the concentration is much higher in a cup of coffee than in black tea. As a result, a cup of coffee has about double as much caffeine compared to a cup of black tea. But yeah it's so soothing to have a nice hot beverage. It's been raining a lot here recently, so we've been drinking a lot of (non-caffeinated) tea in the evening. It's nice! Agree about green tea tasting bad if not properly steeped though.

[@godot5643]

I've heard alot about Qualia.. Have you guys tried that?

[@neurotransmissions]

Haven't tried it, but it does seem to be a popular nootropic. As opposed to the single supplements we tried in the video, Qualia is an amalgamation of a bunch of supplements. I looked at the ingredient list and we covered three of them (Caffeine, L-Theanine, and Ginkgo Biloba) but I'd be interested to look into the research behind the others!

[@africangodman6145]

@@neurotransmissions Do you think Nootropics can cure Autism?

[@curtissjamesd]

L-Theanine in conjunction with melatonin has helped a lot with the quality of my sleep, I had never heard of it being used for focus but that is an interesting idea.

[@whatabouttheearth]

Aint nothing like a gallon of coffee and some crack cocaine in the morning

[@pabloescobar7139]

caffeine has a complete different rection for me. at first it makes me sleepy, and then after 6 hours when the half life is out of my system that is when i am feeling enrgized.

[@teresathomley3703]

Creatine is great if you're strength training. There's a loading phase where you take a shit ton of it and then a maintenance phase to be used indefinitely. Just be sure to do cardio and ab work- or you'll gain weight in areas you don't wanna gain weight in. I experienced virtually no nootropic effects.

[@WILDWILLXD]

Try high levels of caffeine with high levels of nicotine and do something physically and mentally demanding. You'll quickly realize why we went from sailboats to nuclear submarines in a few hundred years. It is a hell of a combination.

[@nicoladmt]

I love how Alie interviewed Alie1, Alie2, Alie3, Cat, Alie4, ... for this study

[@neurotransmissions]

Alie: How did you feel, cat? Cat: MEOW Alie: ...hmmm, interesting.

[@edanur8495]

My doc gave me L-theanine+Phosphotidilcerine+Betain+Folat+B12+DHA for ataxia. Those also named nootropics.

[@tolkakumar6480]

'genotype less sleep more' is that neuro Transmission merch?

[@Djr2699]

Where’s the guy that answers the question so we don’t have to watch all of the video??

[@anthonydied8697]

I have an addiction. I'm addicted to caffeine and nicotine. That s**** for real man

[@charlesmayberry2825]

Coffee.. You're doing it right. Coffee should taste like coffee... not a bunch of added sugar and creamer. On the nicotine note. The problem with it, is that once you're used to it. It's just normal. You don't get a real boost. You just function. Then without, for about 3-5 weeks you'll be absolutely miserable, irritable, potentially sick, anxious. My withdrawls were bad enough when I quit I ended up hospitalized over it. so yeah. Not really worth it.

[@NariKims]

Nice video. :) Been doing some research myself lately on this topic, and there is just so much gibberish out there that you have to sift through. If I may ask, who is the artist of the background track? I really like it, and it sounds super familiar. ^^

[@neurotransmissions]

Yeah, it's hard to know what's overstated marketing and what's real. As for the background track, it's a few different artists! Axel Ljung, Da Tooby, Matt Large, and Anders Bothén.

[@NariKims]

@@neurotransmissions Thank you very much!

[@ciousli]

have you tried piracetam or noopept?

[@Son_of_aesthetics]

I have a question I will be grateful if you answer,I'm a bit obssessed with my brain function,what do you think about weed cuz it improves concentration tremendously and even next day you feel your congnitive is still activated,and about zoloft is it harmful? And what do you think about learning late at nights while you can learn better?Does it harm you? Thanks in advance :)

[@sir.rayrayofthearizona2800]

I used some kind of brain booster supplement when I was younger. It was a free trial and I thought it could be helpful ? I forget the name but I believe it was for improving focus and concentration as well as decreasing the chances of developing dementia. I took it for two days and on the second day I expected one of the worst headaches I’ve ever had. I don’t usually get headaches and there was a warning for this so it must have definitely been the supplement.

[@Son_of_aesthetics]

And olibanum,what you think about it? In my country grandparents believe if pregnant women consume that their baby's mental health will be fine and they may become a genius lol

[@WaveOfEmocean]

Shilajit is a nootropic substance I think you guys should look into. Its a sticky tar-like putty from the Altai and Himalayan mountain comprised of compressed minerals and plant matter over many years. It has the highest levels of humec and fulvic acids known in nature, which has been shown to aid in nutrient absorption. Multiple peer reviewed studies show that it can help balance hormone regulation especially testosterone in men. In an animal study it showed less brain adema after brain damage was inflicted, as well as limiting cancer pathways in ovarian cancer studies in women. Look into it and make another nootropic video! 😄

[@redswap]

NAC works but it has too many side effects to be worth it (the low blood pressure and fatigue kind of cancels it out).

[@ryuuji159]

11:36 Tobacco, Tomato, Potato, EGGPLANTO

[@JohnSmith-ox3gy]

Mmm, Tomacco. *Grgl!*

[@wesleysull]

L-theanine + Caffeine is better than adderall for ADD and general focus IMHO. More sustainable.

[@marvinthielk]

Hey, I've been thinking of doing some nootropic exploration but wanted to have some sort of psychophysics tests or something to evaluate their effects. Or possibly low-cost salivary cortisol testing? have any recommendations?

[@Drawde907]

A lot of these things need to build up in your system you can't just take them once and say they're good or bad especially creatine.

[@TheAldsf]

I know, she takes creatine once and says nothing happened lmao. Its like taking tren 1 time and then saying, "why don't I look like Arnold"?

[@MARIO-sq8gq]

Than why do i have to drink coffe to go to sleep?????

[@RBGRafael]

Omg, this is such a high quality content, and as student of Pharmacy (in the last year), and I never thought about the positive effects of nicotine... Still, isn't worth the side effects, but it's a nice knowledge to have! :)

[@czarnyksiezycrogaty]

If You are student of pharmacy You probably know how to cook amphetamines :) hugs from Poland !

[@Vatican_Banker]

There’s no negative effects of nicotine absent of tobacco. E.g. nicotine gum.

[@Jorge-xf9gs]

​@@Vatican_Banker Dependance, addiction and withdrawal. Impoverished sleep and all that entails (worse cognitive and physical functioning). Neurodevelopmental alterations if taken before 25-35 years old, and at high doses muscle twitching and tics, worse cognitive performance and psychosis. In the worst cases, persistent psychosis after consumption, cardiorespiratory arrest and death.

[@phunku8888]

Bill the cat 🐈 is the star of video. His opinions counts! 😻 Respect the fluff ball lady

[@johnwick4836]

Modafinil is a Reasonably good Nootropic At around 200mg to 300mg I felt pretty Limitless Whilst taking it,, And can be mixed with other compounds for a Greater Effect. Goodluck unlocking your minds Full Potential.!

[@crystals.6859]

Haha! I say this! 😂😂 "What do u take with your coffee? " " Nothing, black like my soul".

[@Son_of_aesthetics]

I swear you deserve more subs! Are you new here?Otherwise that's not rational this number of subs! :/

[@_elenaio_]

Really nice and interesting video -- thank you

[@ekhogroup4506]

please tell us about brain activity on the moment of death. thank you for your interesting videos.

[@artyb27]

Could you take a look at Modafinil? My friends swear by it as a short-term sleep repressant (unhealthy, I know, but useful to get you out of a bind with looming university deadlines) but whenever I've tried it, it either hasn't worked or has had the opposite effect. How is this possible?

[@aena5995]

do u have some sort of allergies? i have been thinking between ritalin or modafinil not sure which one to get ;/

[@DaddyPsyMonn]

@Aena 5 You might have found your answer by now, on which "nootropic" you should take, Ritalin or Modafinil. But I’ll gladly give my two cents on it. I've dabbled a lot in these "supplements" and I go with Ritalin for sure, but with all of these things, you can get some nasty side effects. But if your not lacking f.eks vitamin d3, water and a good diet, your good to go:). In this chaotic time, I find them really helpful. Cheers

[@saw-alone-man6150]

Nooptroics and my adhd meds been a miracle. Plus I have butt load of mental health. I difently see difference I do agree center meds wouldn't help. But see that make me less tired and clear minded. Sometime caffeine make opposite affect for me. Make me sleepy though. I will update this comment later on what med excatly taking. Gingko Bola does help me alot. I take two capsule per day. Baccopa extract been taking too that really help alot compare Gingko Bola.

[@AroundTheBlockAgain]

I hear it's common for people with ADHD to sometimes / often get sleepy when they ingest caffeine. It seems like the same reason why ADHD stimulant medications calm them down vs. the same meds act like uppers for people without ADHD? In my case, it's a dice roll, whether I get too tired, too wired, or nothing at all when I have tea, but I've just learned to avoid it. XD Are you still taking Gingko Biloba and Bacopa?

[@AroundTheBlockAgain]

So gingko biloba makes your blood go more which makes your brain go MORE, and this is? good? And l-theanine makes your neuron fire less and makes your brain go LESS, and this is?? good?? At night when I'm trying to sleep, for sure, this sounds nice. This is the clearest explanation of l-theanine I've seen yet, but I'm still wondering how "neurons fire less" = good in contexts other than sleep. At any rate, I can't handle the caffeine in green tea, so it's pills or nothing for me. XD

[@ErebosGR]

What about the rising concerns about the high levels of acrylamide found in roasted coffee and the court ruling by a Californian judge that Starbucks and other coffee shops need to inform their consumers about the cancer risks under Proposition 65?

[@neurotransmissions]

Yeah, that was pretty controversial when it came up last year. Since that ruling, there have been a lot of hearings regarding this and it looks like they're going to provide an exemption for coffee before it ever goes into effect. This was based on recent studies which found no evidence that coffee increases cancer risk and, in fact, some research has even shown that two cups a day may reduce the risk of certain cancers. Even the FDA commissioner supported its exemption and the World Health Organization removed coffee from its list of carcinogens a few years ago. Honestly, there's just not enough evidence to definitively say whether coffee causes or prevents cancer. But for now, Californians won't be seeing warnings on their Starbucks coffee cups.

[@ErebosGR]

@@neurotransmissions Oh I see. So, from what I read and understand, acrylamide is carcinogenic and found in roasted coffee but coffee also contains antioxidants and carcinostatic compounds that lower the overall risk of cancer?

[@JamesHarshaw]

My whole life I have looked to how to improve my cognitive function. Thank you so much for this video! Request: can you do an episode of things you can do to enhance cognitive function? As well as what to avoid. I will take brain pills but they don't seem to help that much. I do it more for the placebo effect and confidence. Fish oil (Omega-3s) and a multivitamin seems to be the best enhancement I have taken.

[@avi12]

In the Nicotine gum, I think it should have been tested on a smoker, as well as the non-smoker (Micah), to compare the effects E.g. does the gum feel like smoking? If so, does have the same negative effects? If not, how does it influence the brain compared to smoking?

[@neurotransmissions]

Hmmm, good question. Smoking would definitely hit the brain faster because nicotine would enter the bloodstream faster. It would probably have the same effects but would feel slightly different (e.g. "waves" of nicotine stimulation vs. a ramp up and down). Smoking would have more negative effects in general, just because you're introducing smoke particulates that affect the lungs and can cause lung irritation, bad breath, and...ya know...cancer in the long-term.

[@dantwister5106]

I have tried around 40 different nootropics and nothing had an effect on me. Coffee and theanine are a joke too I feel no effect. I'm also not interested in nootropics that make me sleep (wtf?), or in cognitive improvements, because that is not going to happen. What I care about is less anxiety, more energy and better libido. I screwed my test up with cistanche because I only took 200 mg. But Taking 600 mg Cistanche tubulosa and eating 3 eggs may make you feel better for around 30 mins. Afaik it improves cholesterol transport.

[@reganmclachlan234]

Your diet must be the issue my friend. Try Fasting.

[@VWYL900802]

my ex recommended me to try phenibut, any ideas?

[@idanzigm]

Watch him take the nicotine gum like… are you a junky yet 😆

[@Adeline9418]

Right now I take quality multi,b Complex and ginkgo. Seems to work. Oh and black tea. May switch to coffee when the tea is gone.

[@andrewsilver7048]

@ 12:00 Your throat is about to burn haha

[@Adeline9418]

I love ginkgo. It helps me at work.

[@gwr4fun]

Your hair hat struck me

[@romansiguenza8738]

rec doses ? esp for L theanine

[@zynark777]

Mmm. Cocaine, Doctor. Prescribe me some of that original Coca-Cola.

[@triremenes1791]

Alex Jones in the video. I already have no better event to happen in a week :D

[@Rueyful]

Great video

[@tobiasthorsen2995]

ok

[@tomfromoz8527]

This video speaks to neurotypical people ONLY. As usual neurodivergent people are very different, and not taken into account. We may currently be counted as a minority, but that may change as more adults and doctors become aware. I do believe that "hyper-focus" is something that only we are truly capable of. > Pam

[@rickharold69]

Very interesting. Thx!!

[@addj7093]

Nope

[@hypercortical7772]

adorable cat

[@MadSaurax]

Why do all Noootropic youtubers take videos infront a book shelf? Is it to make you seem smarter than you are? Did you even read those books? This whole industry seems like a fucking scam tbh, including the people doing the reviews

[@dutchik5107]

Damn. Maybe i have a creatine defficiency and is my recent (a year now. Bit shorter than being a vegatarian) innability to focus. Even on meds. Not due to stress. But just a creatine defficiency. And i thinking those mock meats are fully supplemented. With like B12 and Iron and all.

[@neurotransmissions]

Oh dang, that is possible! Although stress can also cause focus issues. Might be worth trying it out though if you're struggling. 😊

[@StaticTeaz]

shalom

[@restupido3691]

🌷

[@naim3552]

Of course you wont see the point of nootropics. Trying some ginko , creatine and l-theanine once (which btw i dont even consider as nootropics) and reading some online articles wont make you an expert who can gives advices on the topic. For anyone watching this video and trying to improve his life and mental performance, i would like to say: keep searching. There are lots of good informations and youtubers out there knowledgeable about the subject. Nootropics were a real life savior to me. You have no idea how dramatically it can improve your life. Dont be discourage and mislead by this video.

[@restupido3691]

Cfe

[@JackiesVids]

😍

[@restupido3691]

💶💶💶💶💶

[@Fallibleandflawed]

🥰

[@azazelhaque8873]

Make short videos

[@TheOgi22]

Madmonq?