Polycystic Ovarian Syndrome (PCOS) - Pathophysiology, Symptoms, Treatment

This video thoroughly discusses the pathophysiology of PCOS and also includes manifestations and treatment. It can cause a vicious cycle with increased androgens and increased insulin/insulin resistance.

[@ImNotFromThisPlanet]

Amazing how you got Pedro Pascal to narrate this video. All jokes aside, amazing explanation and video.

[@gemstonerose4648]

For sth that has been happening to my own body for over half my life, its amazing to finally understand the exact reasons of it. Thank you!

[@Niyati_sankhe]

You made it so easy for me to understand...thanks a lot for such great explaination & video too ♥️

[@debigdogk9563]

ONLY A GENIUS like you can deliver such an extraordinary teaching skills. GOD BLESS YOU FOR THIS WONDER JOB. ❤❤❤❤❤

[@physiopathopharmaco4190]

Wow, thank you

[@ifrahakbar5462]

People like you are blessing to this world ❤️

[@Ibhazeblessing]

I have PCOS and I remember how I felt when the doctor told me it would be hard for me to conceive I now have 4 children very successful pregnancies. God blessed me! with use of herbs 🌿

[@pfvxuxu]

Best video about Pcos and IR available in you tube. Thank you!

[@vaishnavikhare8596]

i m no med student, i just came here to understand whats happening in body. Thanks sir !

[@debigdogk9563]

I never thought I could understand this topic, but you made it so simple to understand. Thank you, thank you, and thank you. God bless you for teaching ❤❤❤❤❤

[@Mariamfa_]

Thank you so much for creating this video I truly appreciate it. It's so informative, organized and saved me tons of time to understand and review it.

[@physiopathopharmaco4190]

Glad it was helpful!

[@italogabriele7721]

Excellent expanlation. Very graphic. Thank You !

[@nastarannazari5062]

I love your channel!!! We have to pay for college and then come back to KZbin for understanding the concept totally.

[@vanshajchandra8031]

Such an underrated video ,you deserve more views

[@thewholehealthlab]

really love the short quiz with explanations at the end!

[@readybride6838]

Precise and concise explanation. Thank you

[@adegokeadewumi5390]

Best explanation ever😭Thank youuuu

[@blacktongs]

Best video yet, goes really well with your estrogen and progesterone production video! subscribed! Thank you :)

[@syedafiya687]

Very helpful ! Keep up the good work🎉

[@sindhsaiyam]

Wow what an explanation plz tell us how we can get rid of PCOS

[@nghiapham1644]

Best explanation yet!

[@fdejvbhtjc4927]

Great explanation👏 thank you very much

[@kashishganglani2237]

Phenomenal work......you have made easy to learn and time saving lesson. Waiting for more such videos.

[@makeeasy3891]

Highly recommended this video 👍👍 Thank you guys who made this..❤️❤️

[@Dr.PraveenyaMahanthi]

Excellent excellent no Great textbooks have explained this way

[@roo8ro847]

Amazing explanation ! Thank you 🤍

[@physiopathopharmaco4190]

Glad it was helpful!

[@makyd6275]

thank you so much!! amazing ♥

[@yasersibai6595]

Very useful. Thanks alot

[@parinaverma8984]

thankyou for the great explanation! it cleared all my doubts😀😀

[@dingdong436.]

Superb explanation. Thank you very much!🤩

[@lukenelson6027]

Excellent explanation

[@Qamarali1]

Thanks for sharing Very informative

[@eliseeidem9092]

Amazing video, thank you!

[@dashimansu]

very nice explanation..THANK YOU !!!

[@MoustafaElattar1]

Great explanation, thank you 🙏🏻

[@ahmedbasim7368]

Sir you are amazing 👏

[@tuannguyenuc395]

Thank you so much for this explanation!

[@physiopathopharmaco4190]

You're very welcome!

[@laurenhoffmann7978]

this is AMAZING

[@euniceowusuansah8685]

Best video

[@olvembeb7024]

amazing

[@dianajamous6644]

wonderful

[@mariamoghimi7713]

Thank you for this video! Brilliant explanation :)

[@georgebacon4720]

Fantastic video - brilliant explanation! Thank you :)

[@Pratikshashelke-m8f]

Soo good. And detail information .thanks

[@ricardotorres8114]

excellent

[@JosyJosy-x6q]

very good explanation, thank you so much

[@ghazalmohseni5935]

Great👍🏽

[@rechardwarlson7066]

Thank you , excellent illustrations

[@dr.nitikasingh4564]

What an amazing explanation 😃

[@bawanomer1244]

Thanks

[@yasminkhattab3473]

Thank you This is very helpful

[@ranifaizagul8558]

Wow explanation

[@PsychicReadingUsaFacebookGroup]

Definitely wasn’t planned with pcos at least not so soon and ended up with twins. We’re both happy though

[@safurabano8212]

Awesome

[@ghostintheshell1431]

Awesome video, thank you🍀

[@dailydoseofmedicinee]

Good explanation 👍

[@mohammedmatar2705]

Thank you so much doc ❤️❤️

[@obayrafi2632]

Very greatly explained, thank u

[@suhafares373]

Great explanations thanks

[@Ultrman97]

Great explanation thank you

[@fathimamohamedali5267]

Both ovaries are bulky and shows multiple peripherally arranged follicles with echogenic stroma_ POLYCYSTIC OVARIES

[@dilafruzkhamidova_]

Great explanation 👏

[@sirapobpotjanapimol5148]

God’s EXPLANATION

[@ibraheemalma]

Thank you!

[@MrAndyroni]

Excellent.. 👏 👏 👏

[@cleopaschisanga5355]

Best explanation man

[@abhisheksuraj4992]

Thank you.. Great explanation

[@emilybaker760]

Metformin really helps!!!

[@jay5281]

Yeah, do you have anything else to say about the drug other than that?

[@harworld4947]

you are amazing 👏🏻👏🏻

[@MichaelAlanAlien]

Is this a dangerous situation for my lady. Thank you

[@nadiabehlouli2403]

Thank you

[@sephoraahsan577]

As read by the mandalorian

[@50naflanoorin41]

😍😍nice explanation

[@prasannabharathi2019]

Supperbb❤️ explanation 🙏

[@Imhosanna]

You sound exactly like Pedro pascal

[@miruuish]

Hi and thank you for your compelling video about this condition! I have one question, please. If low progesterone (due to lack of corpus luteus genesis) is the cause of the increased frequency of GnRH secretion through the physiological negative feedback, doesn't that already imply ovulation not happening? I think I didn't get the primum movens of this vicious cycle correctly. Is it the hyperinsulinism? Thanks :D

[@daisyy2126]

Perhaps that’s why it’s thought to be a chicken and egg scenario as doctors aren’t sure what causes it. I’m not sure though I’m not a doctor

[@esikaesther4448]

Thanks for the video, however I do have a question. 3:19 What is the basis for the production of the insulin by the pancreas and what makes it abnormal and different from a patient without PCOS?

[@RFN871]

Great 💚

[@esraaabdel_shakoor6609]

V helpful ✨ 👌

[@nonyeonochie3250]

Greatttt🙌🏽🙌🏽

[@bliza9220]

hey yo, you are amazing

[@hindujag4948]

Master

[@DeponsiaYrn-go6yh]

When young I have had a lower back xray after a road accident where they checked if my spine was fine. Years later I have cysts and irregular periods. and I'm wondering if the xrays are the source. Especially since no one in my family has the irregular periods

[@Cryptokite019]

Sir have a que ,if progesterone comes after ovulation and from carpos luteum ,then then how it will be the cause for gnrh high frequency ,as in pcos the follical doesn't ovulate. The how progesterone will come to cause this. Please tell🙏🙏 Is it occurs in next cycle?

[@xyzpeace7814]

❤️❤️❤️❤️

[@aquachik18]

thank youuuuuu

[@opaloakley]

I have a perfectly regular period every 29 days. Does that mean I ovulate?

[@luciramos8526]

Same here !?????

[@ryanlwan]

Highly likely , however , some have periods without ovulating , gynecologists can test for this though.

[@nadinethart]

Thank you for the video! I just had one question: what if you have diabetes type 1 and PCOS?

[@Cryptokite019]

If you understand then can you clear up my doubt

[@Cryptokite019]

have a que ,if progesterone comes after ovulation and from carpos luteum ,then then how it will be the cause for gnrh high frequency ,as in pcos the follical doesn't ovulate. The how progesterone will come to cause this. Please tell🙏🙏 Is it occurs in next cycle?

[@shujiafzal2187]

@@Cryptokite019 In the normal menstrual cycle, when the graffian (antral) follicle ovulates, the egg is sucked up into the fallopian tubes whilst the remainder of the follicle at the ovary becomes the corpus luteum. Normally, the corpus luteum produces progesterone which exerts negative feedback on the hypothalamus such that GnRH pulsatility is decreased to reduce LH/FSH levels and prevent further ovulation. However in PCOS, the follicle does not ovulate such that the corpus luteum is not produced - the follicle remains as an arrested pre-ovulatory follicle in the ovary thereby owing to the polyCYSTIC aspect of PCOS. As there is no corpus luteum, there is NO progesterone produced to negatively feedback on the hypothalamus - as a result GnRH pulsatility increases. As fast GnRH pulses favours LH production, there is a high LH:FSH ratio. The high LH leads to increased androgen production via theca cells which cause hirsutism and acne, alongside insulin resistance which also amplifies further androgen production as it has co-stimulatory effects with LH. On the other hand, low FSH prevents complete follicle maturation as there is no inter-cycle rise/fall such that there is no selection of a dominant follicle. This is why PCOS women present with irregular menstrual cycles and anovulation.

[@Cryptokite019]

Please tell

[@MsPearl_]

Hello , Can you please explain, what does it mean on the diagram " ...past failed ovulation events" ??? What does this mean someone tell me please . Thank you

[@Medicalblocker]

Why The FSH don’t rise too?

[@ahmedaziz8725]

Gòod job

[@crazypiper9749]

legend

[@PriankaEvangelineSLP]

What causes high insulin in pcos?

[@realimagevanity2289]

High insulin is the result of modern lifestyle, I suspect mostly derived from our messed up quality of foods. Almost 90 percent of Americans have insulin resistance. As you get older the insulin resistance gets worser.

[@disha5250]

And also Obesity too

[@maryanngelia9309]

👏👏

[@italogabriele7721]

* explanation

[@christinapant6979]

Fatty liver disease is the cause of pcos so the only way to fix iti is losing the belly fat

[@amonmayoyo304]

Chibaba icho ❤

[@lisak6343]

excellent

[@aliabduljaleel4295]

Thank you !!

[@ओमकरंबळकर]

Thanks