Regulation of Renal Blood Flow

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[@sheyamckell4856]

My final year project has a lot to do with blood pressure regulation. Thank you guys for helping me out with this 🙏. Truly life savers

[@osmosis]

Our pleasure to help, Shreya! 😊

[@katiefaery]

I've recently been diagnosed with glomerulonephritis, I have no medical background. This has been so useful to me, thank you ♥️

[@osmosis]

Glad that we're able to help, Katie! And sorry to hear about your diagnosis. Wishing you the best of health today! Keep safe! ❤️

[@jck4life252]

I wish ur better now maam

[@thefenerbahcesk4156]

I have a medical background (2nd year med student), and you would be surprised how much I learned from this video.

[@azizullah5632]

Sir I found your lectures on KZbin, one of the best teaching method Thank you for your help with medical students

[@osmosis]

We're glad that you find our videos helpful, Aziz! 💖

[@Emma-db2nj]

Love your video! I'm a pharmacy student studying for an exam and this is really helpful

[@osmosis]

Glad it was helpful, Emma! 💕

[@Hannaneh2004]

As a medical student I found it very useful 👌 Thank you so much Osmosis 💓

[@osmosis]

Most welcome! ❤️

[@miranmuslem]

Once again... an amazing video. Please don't stop posting!

[@osmosis]

Thank you! ❤️

[@KillerTacos54]

Thank you for these amazing videos

[@GM_LEONG]

Currently finishing a renal term. These videos have been super helpful as a refresher!

[@osmosis]

Glad it was helpful and thank you for making us part of your review! 🙏🏼 ❤️ 😊

[@12SA472012]

Great video, but you missed out on mentioning the other, arguably more important, aspect of tubuloglomerular feedback mechanism. When the macula densa cells detect less sodium in the tubular fluids, which usually occurs when GFR is reduced due to low blood pressure, they lead to release of renin from the juxtaglomerular cells, and that eventually leads to increase in GFR and blood pressure.

[@osmosis]

Thank you so much for bringing this to our attention, Sankalpa! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊

[@liz4228]

so thankful for your channel

[@osmosis]

Aww.. Thanks, Liz! 😊

[@nomanshaikh8640]

Perfect teaching style, superb.

[@osmosis]

Thanks, Norman! 💖

[@elquixotedelascanarias]

Great explanation and delivery - thanks.

[@osmosis]

Glad you enjoyed it! 😊

[@natesanjyothikumari5256]

Very good informative video

[@jennifermatillano8808]

Best physiology video I've seen.

[@osmosis]

Wow, thanks! 🥰

[@khokhahamdan9452]

Thank you your lectures are very helpful ♡

[@osmosis]

You're very welcome. Khokha! ❤️

[@geniuspeng]

Thank you for this very well-done and easy to understand video

[@osmosis]

Glad it was helpful! 🌟

[@zeevberar1663]

THANKS

[@bharatb652]

next level teaching, helping me a lot sir,please sir make more videos on physiology

[@osmosis]

Glad to help! 😊

[@AnitaPrasad12]

Very nice video, helped out a lot

[@osmosis]

Glad it helped! ❤️

[@manuanimations7228]

Omg, I Love your videos!

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Thanks, Manu!

[@Laur3n13]

Thank you thank you thank you!

[@osmosis]

Happy to help any time! 💖

[@kacinichols5827]

Very helpful! Thanksss

[@osmosis]

Any time, Kaci! 🙏🏼

[@ImaniNatashaa]

Question, at about 5:40, it said that with high angiotensin II, this will cause both afferent glomerular arteriole and efferent glomerular arteriole to constrict causing a decrease in both renal blood flow and GFR. I agree with a constriction in afferent arteriole causing a decrease in renal blood flow but wouldn't constriction in efferent arteriole cause an INCREASE in GFR? Like say a patient has low blood volume and therefore low BP and low GFR, the release of angiotensin II is meant to increase GFR, not further decrease it right?

[@aadityalimbachiya3794]

@6.42 u told that Pg dilates both efferent and afferent arterioles but u written dilation of efferent and constriction of afferent arteriols pls clear

[@Michelle-lf3cs]

Hi ！I'm Michelle,from hk. I, who is a junior student from Biometical Science, am so excited to know about the lecture

[@osmosis]

Wonderful! 😊

[@jawaherturki6592]

thank yooou❤❤❤! but i have a simple question ( why increasing systemic pressure increased the pressure gradient? i think as a result of increasing systemic pressure both the systemic arterial and systemic venous pressures are going to increase so the different is the same )

[@christiancolon177]

You are the best!

[@osmosis]

Wow, thanks! ❤

[@kawthar7609]

great and great explenation for ever❤❤🌟🌟

[@osmosis]

Thanks, Kawthar! 🥰

[@elquixotedelascanarias]

BTW, no amount of arterial resistance will prevent a chasing kangaroo from hunting you down. Usain Bolt sustained an average ground speed of 37.58km/h over his world-record-setting 100m bolt in 2009, over 9.58 seconds. Roos will sustain 40 km/h for about 2 km. At that speed, that's about 3 minutes. Ergo, under 10 secs, that roo will tailslap Bolt for his cheeky escape attempt, without breaking a sweat.

[@noahleveille366]

Was trying to look up the Renai Circulation song but this works as well

[@osmosis]

We hope it helps! 🥰

[@Nour_Astella]

How cathecolamine work on regulation of renal blood

[@baisakhipramanik7724]

Please tell me the 3 sphincter name in bladder....?

[@AnakinIHaveTheHighGround]

Teach told me to watch

[@janosvas8597]

Who experienced blockage because of the prostata? And what happened after this? And are your kidney parameters going back to normal (BUN and creatinin)? I experienced a blockage and I was underwent to TURP in May 2022. My BUN and creatinin-parameters worsened because of the blockage. Is somebody who experienced the same? Returned at you the BUN and creatinin value to normal? Or not more? is to somebody happened the same as to me? I was already 6 years on BPH medication-finasterid-aglandin, as the retention happened. The Kreatinin and BUN were worsened after the retention. And now the question: In your experience the Kreatinin and BUN were going back AFTER the TURP, or not? Thank you and best greetings from

[@zahraa_1920y]

Perfect💛

[@osmosis]

Thanks! 💕

[@adrummingdog2782]

I have never heard a single soul say capillary that way lol

[@mistyconstancio6459]

😂

[@rename_525]

nice

[@fathimareehathabdulrazack8423]

That's very useful thanks. 👍 Is there any chances to get the notes ... Because it's so useful ig.

[@osmosis]

Hi Fathima! We do have high-yield notes for this video that you may access at osmosis.org. You may sign-up for the 7-day free trial (no credit card required) to access this and more. If you have questions or concerns, please email us right away ([e-mail]) and our team will be glad to help! 😊

[@abantikakonar6480]

Fantastic

[@osmosis]

Thanks, Abantika! ❤️

[@natashakapungwe8586]

From your explanation about ANP and BNP increasing renal blood flow by constricting the efferent and dilating the afferent arteriole.... Does it mean that low levels of Angiotensin II also have the same affect of increasing renal blood flow since they only constrict the efferent?

[@STARMAN33]

I think so. People with renal artery stenosis usually have an slightly increased angiotensin levels which helps in maintaining gfr . Use of ace inhibitors / arb blockers can hamper this.

[@ayomidejohnson2659]

No, since ANP and BNP work during high blood pressure so there is an increase in renal blood flow. But for Angiotensin ll happens during low blood pressure just to make more blood remain in the glomerulus to maintain the GFR.

[@faithacuesta9930]

I thought the renal corpuscle only consist of the glomerulus and the glomerular capsule

[@Silvia-wi8yx]

Why doesn't Glomerular Filtration Rate increase despite the lack of autoregulation when blood pressure gets higher than 200 mmHg, while renal blood flow increases drastically? Thanks to whoever can answer me.

[@shatha5170]

Woww! 💜

[@bionium6976]

Osmosis of knowledge into my brain

[@osmosis]

🙌🏼 💕 ✨

[@kashmirakanojiya9475]

Can you make a video on ( law glomerular filtration rate (GFR)) Please

[@osmosis]

Hi Kashmira! We do have a video on this over at osmosis.org 😊 Feel free to signup for the 7-day free trial to access this video.

[@janosvas8597]

what is the reason that you have a low GFR? For me it was an urin flow blocade. In the meantime I had a TURP, and for me the question is, if the GFR will increase, or no? What doctors you were consulting? What therapy the doctors proposed to you? best greatings from Vienna

[@cardiyansane1414]

Very well done…I had to slow it down to x.75 speed coz it was too fast

[@easyartskitchen4361]

Which app do u use?

[@osmosis]

Hi! Thanks for asking! Here’s how Osmosis videos are made: www.osmosis.org/blog/2020/11/27/how-osmosis-videos-are-made# 👍🏼

[@margaretrobinson9597]

There are two types of kidney infection.

[@aasemahsan]

2:43 7:23 autoregulation

[@hannairfan]

similar to cognito🤔

[@ThatsWhy-]

OMG! At the beginning you said when blood pressure goes high blood flow goes down. But in the end you said when blood pressure goes up blood flow goes up ! How is that ?

[@osmosis]

Thank you so much for bringing this to our attention, Issaali! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊

[@abul3ezz30]

The tubulo glomerular feedback is wrong and is the other way around beginning with low flow and low GFR that later on causes afferent vasodilation, efferent vasoconstriction, and release of renin. Plus it is not explained thoroughly. Otherwise perfect video

[@anuragnath8182]

It can act both way. I mean low gfr , low NaCl causes macula densa to create vasodilation therefore gfr increased (i.e brought back to normal level) Similarly when high gfr, high NaCl macula densa releases adenosine which contracts afferent arteriole and decreases gfr(i.e brought back to normal level) Hope it helps 😊

[@hocinehamiani1156]

{ هذا خلق الله فأروني ماذا خلق الذين من دونه بل الظالمون في ضلال مبين } This is the creation of Allah. So show Me what those other than Him have created. Rather, the wrongdoers are in clear error

[@ujjalsharma9083]

69 comments before I commented

[@lyndawolfe8564]

WHY ARE WE CALLING THEM Cuh-pill-er-ease

[@Duskysky1]

Osmosis makers aren't Australians why do they keep giving the kangaroo example

[@carolclark5776]

Kangaroo hee

[@sepehrasgharzade8626]

Speak very fast😐

[@osmosis]

Sorry about this, Sepehr. You may adjust the video's playback speed by selecting on the settings icon on the lower portion of the video player to a speed that's more comfortable for you. We hope this helps 🙏🏼

[@jessicarivers3464]

did not help at all, if i couldnt underst my professor this videos made it worse!!