T Cell Development

[@bbartukoglu]

It is admirable that you share valuable information without trying to get a benefit from it unlike many other posters of this site.

[@chuasiyu]

Wow I'm sitting for my Immunology paper tomorrow. This came in handy. Thanks!

[@gishamolmathew1601]

This is an excellent video and an excellent way to summarise the topic! Thanks for uploading!

[@Lifeiis]

Cheers mate, this is definitely going to help me with my Immuno exam tomorrow!

[@nstar0708]

Can you explain the HY model for MHCrestriction or CD4/CD8 commitment?

[@cuentodenada]

great pathology series martin

[@aaronschaller7120]

T regulatory cells are CD4+ and CD25+

[@sangshahi6845]

What determines whether a T cell becomes a cytotoxic or a helper T cell?

[@anacvetko1542]

Karan Giri if it binds with mhc I on an APC then it becomes t cytotoxic, and if it binds with mhc II on APC, then it becomes t helper

[@ubaidullah-mv8dz]

+Ana Cvetko hi

[@anneeq008]

that wasn't exactly what he was asking...

[@nikpaschal]

Not an easy one this one... strength/duration of signaling, cytokines, TFs you name it. There is a classical and a stochastic model but you can always do some out of the box thinking after you digest some of the key facts --> www.ncbi.nlm.nih.gov/pmc/articles/PMC2760737/

[@mna882211]

ooh !!! that was beneficial & helpful > could u do such tutorial about HLA ( MCH ) system please ??!! . I'll be thankful & it'll be useful as a complexed system to get .

[@septinsutin8424]

thank you so much. but I think you can make t cell development part 2 as clear as your explanation on b cell development videos.

[@abeboy6155]

Great video but there is a mistake. TCR(B) locus rearrangement is not between DN1 and DN2 (Not DN2-DN3). Between the DN2 and DN3 is where T-cell commitment happens.

[@hasanmarei3623]

thank you. it is so clear, easy to follow you,and you make it so Interesting.

[@zannatul23]

skipped through the whole video, didnt find it that helpful this time i thought u were going to go into more details of T cell is actually selected

[@sobster123]

5:30 ok im goin for a slash, fuck it!

[@mekamalika]

grt info.. thnks... but plz get a bit louder.. low sound is ear straining....

[@hashashaabdi687]

who else liked before even watching it.

[@wendelynoslock92]

This was much less useful than you previous videos. I was hoping for a discussion on positive selection and negative selection. You also did not mention the gamma or delta chains; the cytokines that produce different helper T cells; or AIRE.

[@TheIegend27]

My mom had hypogammaglobulinemia which is a Tcell maturity problem, She did not have helper cells

[@Placebo201]

saved me in my immunology course

[@daauus]

Thanks you explained so Clear. Thanks Mr. Harpin

[@jamesdeen89]

these videos are golden

[@Emmathe12th]

volume button?

[@melinabaltogianni]

Incredible video! Thank you so much!

[@fathimazahara6770]

It is really helpful for me... thank you so much!

[@montecristo1693]

First thank you very very much you explain biology with such simplicity great method as mathematics 1+1=2 .I'm from Algerai you help me thank you again .

[@lexusfan100]

great stuff..but could you increase your vocal. i have to increase my volume to max in order to hear.. or maybe i m going deaf ..lol thanks

[@mekamalika]

got max vol. still heard low....

[@abunadia9199]

Thank you, beautiful diagram

[@shaban4815]

Very useful 2023🎉

[@mkamareddine]

this was absolutely wonderful! thanks mate

[@rehamyoussef5334]

This vedio was very helpfull . Thank you .

[@lordshifu]

Gonna take a printout of the final pic and hung it in my wall

[@nicodasm]

Nice video. Thanks

[@jurisicdjina]

Sir, you are exellent !!!

[@hawraal-magdy5476]

Thank you very mutch!!!!

[@tahmiharir8573]

One of the best videos ever!!! Please make more videos, especially for biochemistry!

[@ignaciofrancis8806]

Instablaster...

[@nooshinmirzaee7008]

thank you it was really helpful

[@habibjoukhdar]

You are a god amongst men!!

[@shairamukaram2039]

very much helpful; thanks!

[@beautytipschannel6674]

Awesome 👍

[@lonly4uonly]

many many thanks sir

[@dr.archansil5550]

Simplified but incomplete. No detailing and sound quality is very poor

[@prisce7642]

woooooooow you are amazing literally saved me! thanks!

[@rohitkumar-et3np]

thanku for this video

[@marandisuchita4097]

Super

[@OmarQ90]

CLS

[@TomNouri]

omg wtf is c-kit lol. thx for the vid ;)

[@devangbarot5092]

An enzyme Tyrosine Kinase.

[@gregc7169]

5

[@vishalupadhyay416]

?

[@francileudosilva6482]

E BOM

[@ManishYadav-id7wl]

Great video ... really explain very bad ....not happy

[@sobster123]

fok sake man can you speak a bit louder?!!!!!! Hate havin to blast ma volume jus for your quiet ass vids!

[@ajvelasco8442]

sobster123 can you atleast thank him for the efforts geez