T cell subtypes | Th1, Th2, Treg, Th17 | Cytotoxic T cells | exhausted T cells

[@summatim]

0:01: T cell subtypes 1:10: T helper cells 4:20: T cell activation and differentiation 5:17: Th2 cells 5:53: Th17 cells 16:11: Cytotoxic vesicles lead to apoptosis 16:32: Activation of caspase 3 leads to apoptosis 17:40: Memory T cells play a role in immune response 21:05: Exhausted T cells are important for cancer 24:29: Negative core stimulation is a key mechanism to drive exhaustion

[@ganeshpatnaikdabiru1907]

Q

[@szilardmali2998]

Extremly useful video! It made many topics clearer for me! Thank you!

[@animatedbiologywitharpan]

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

[@exciton007]

Thanks for all the videos. It would be helpful if there would be a cursor/pointer during the presentation. This would simplify the understanding.

[@animatedbiologywitharpan]

Thanks for your suggestion. We will incorporate this change in future videos

[@Priyanka-dh7wu]

Hey!!!!!! Ur vedios are truly commendable A small request, plz start a proper series for exams like csir net, ur content and way of explanation is amazing It will surely reach heights.... Plz keep going!! 🌻

[@animatedbiologywitharpan]

please check out my playlists (www.youtube.com/@animatedbiologywitharpan/playlists) already there is unit-wise content for CSIR NET. for example Unit13 is named as biotechniques, Unit 5 is dev bio... so on. Definitely take a look. These videos are better than any existing institutes. share with friends

[@animatedbiologywitharpan]

For further queries Whtasapp us at [phone]

[@Priyanka-dh7wu]

@@animatedbiologywitharpan thank you so much

[@gayathriselvaraj5082]

Very useful sir thank you

[@animatedbiologywitharpan]

Please share my channel link with your friends and help me to reach big audiance. Don't forget to checkout immunology playlist kzbin.info/aero/PLKtiwIJ8Q7rq77W7r4cXPrbhi_VpLWw8c

[@animatedbiologywitharpan]

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[@mariaochoa9387]

Very interesting 👌 thank you

[@animatedbiologywitharpan]

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[@shreyakaushal8296]

Hey arpan sir can you plzzz make a video on interleukins in detail it will be very helpful Sirr plzz

[@animatedbiologywitharpan]

OK thanks for the suggestion, are you a med student ?

[@kavitavats3581]

very good video

[@animatedbiologywitharpan]

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

[@saptarshighosh3864]

Respected Sir, during Crohn's disease, the Pro-inflammatory cytokines should be more than Anti-inflammatory cytokines... Because the Treg cells are of less quantity than Th1 and Th17... but the seesaw is showing the opposite thing...

[@animatedbiologywitharpan]

The seesaw is bit confusing. I thought pro-inflammatory cytokines has higher weightage hence the seesaw will dip that side. May be I should have used arrows to explain this. Any way thanks for all the feedback. Seriously it will help me to improvise

[@il3mendo]

Is then th17 connected to autoimmune disease, th2 allergy response and th1 cancer ? Is the prolonged th17 expression connected with th1 ?

[@animatedbiologywitharpan]

Th17 is associated with auto immune disease and neurological disease like multiple sclerosis. also its role is important agains fungal infection. detailed video kzbin.info/www/bejne/nJSnp4OAps6qfpIsi=F8Z8lb7ptkJJlC6P

[@animatedbiologywitharpan]

multiple sclerosis kzbin.info/www/bejne/eavGmaxobK14fbMsi=J_DzzJlK_fzoJXiV

[@il3mendo]

@@animatedbiologywitharpan Usually autoimmune diseases will lead to neurological diseases, am I wrong ? Are autoimmune diseases associated just with the Mch 2 or mch1? If Mch 1 Is triggered by Mch 2 that means that the epigenetic is leading the pathology. Am I wrong ?

[@il3mendo]

@@animatedbiologywitharpan I have always been stuck on the dq2 (celiac disease). Could we say that Mch 2 is an Cd4 while Mch 1 is a Cd8 ? I know I am a pain in the ass

[@dr.shadmbbsdphmasco]

Yes ​@@il3mendo

[@srikantadash4603]

Can u please provide a link for ur video. T cell activation. I really in need of it. Please bhai send me

[@animatedbiologywitharpan]

kzbin.info/www/bejne/iJCcnYGFd96Dpqcsi=QfjDcfL98Nc1OTlg

[@rutikghagare4992]

Cytotoxic T cells also need to be activated by the APC to be functional because normal cell infected can`t give costimulatory signal please confirm once

[@animatedbiologywitharpan]

yes cytotoxic T cells needs to be activated as well.

[@djsaurabh007]

SIr at 9min 23 sec you say that IL4 activates TBET gene , shouldn't it activate GATA3 ?

[@animatedbiologywitharpan]

yup, it was a mistake it is GATA3

[@animatedbiologywitharpan]

I suggest you can refer to this article.www.sciencedirect.com/science/article/abs/pii/S1471490614000593

[@zembounsyhalard6222]

I wanna know that cytotoxic t cells are activated by infectious cell,Are their naive?😅

[@animatedbiologywitharpan]

Sure I will make a video on cytotoxic t cells in details