The DAILY HACKS To Look Younger, Live Longer & REVERSE YOUR AGE | Dr. David Sinclair

As you know, it’s my mission to help teach you how to build the MINDSET and SKILLS that will help you live an extraordinary life - and over the last few months I’ve been working hard behind the scenes to help create a brand-new tool that will help you do that. It’s called Kyzen - and I am proud to announce that I will be bringing it to the world later this year to challenge you to empower yourself and accomplish greater things in life. To learn more, join my Discord at impacttheory.com/discord
Show Notes:
The fountain of youth is a mythical spring that has been the basis of many Hollywood movies and cosmetic marketing campaigns! Our obsession with youth and being young forever has been the source of cosmetic surgery and endless stories of ‘back in my day’.
David Sinclair is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for Biology of Aging at Harvard Medical School. As a professor, scientific investigator and co-founder of multiple biotech companies, his knowledge with epigenetics and reverse aging is highly regarded among professional colleagues in the industry. He’s appeared on dozens of podcasts, written books, and hosts his own podcast, Lifespan. As a guest on Health Theory the conversations around reverse aging and biological clocks are more than enlightening.
Finding the root cause to aging and understanding how diet, exercise, and lifestyle choices impact our aging process puts the power of perspective and knowledge within your control. You don’t have to guess or hope for a mythical spring of magical water that holds the secret of youth. You can make a decision everyday to turn back the clock, slow the aging process, and reset your age.
SHOW NOTES:
0:00 | Introduction to David Sinclair
0:12 | Daily Hacks to Slow Aging
28:50 | How to Reset Your Age
58:43 | This Causes Aging
1:32:23 | How to Understand Aging
QUOTES:
“80% of your longevity and health in old age is controllable and only 20% is dictated by your genes, the genome. The rest is your epigenome that responds to how we live [7:36]
“Our livers are much smarter than our eyes and our mouths…” [24:35]
“Anything that stresses your body, puts it into a state of shock is good in the long run.” [38:16]
“When I boiled it down to its essence I realized aging was a loss of information.” [1:01:58]
“That’s part of the problem with aging, which is genes getting turned on when they should be kept off for decades, and then cells start to get confused.” [1:14:17]
Follow David Sinclair:
Website: sinclair.hms.harvard.edu/
KZbin: / davidsinclairpodcast
Podcast: anchor.fm/lifespan
Instagram: / davidsinclairphd
Twitter: / davidasinclair
Facebook: / davidsinclairphd

[@TomBilyeu]

What do you think is the most impactful anti-aging hack?

[@dkhowimalivev3633]

SOUP

[@dkhowimalivev3633]

SPF

[@dkhowimalivev3633]

Water

[@mikehus7439]

Sport & KETO / Carnivore-diet

[@nathaliecaron1970]

apple cider vinegar

[@colinlaidlaw7661]

I've watched IT since start of 2020 - one of the best KZbin shows made. The most impactful things to keep young are: 1. Whole day FASTING or intermittent fasting 2. Get rid of or reduce refined sugar and refined carbs! 3. Mostly whole and organic foods 4. Micronutrient density - vitamins/minerals 5. Ditch inflammatory vegetable oils 6. Sleep well in darkness and stay cool at night 7. Exercise using sprinting/resistance training 8. Breathe work and meditation - parasympathetic style 9. Get social, find a partner, have connections 10. Find enjoyment and solid routine Bonuses: Trans resveratrol, metformin, cold water therapy - research before implementing anything

[@gstylez0107]

You left out NMN... That's kind of a big one with Dr Sinclair

[@cytx6835]

thanks for sharing, would you have an example of diet that materializes this? thx!

[@rawstarmusic]

It's not gonna matter much unless it changes the genes. You could be healthy though.

[@murrmurr765]

What is IT?

[@Semabachos]

@@murrmurr765 Impact Theory

[@riddlerhymes512]

I've followed Dr. Sinclair, read his book and follow most his protocols...EXCEPT for the the mostly vegetarian diet. I fas till noon and eat lots of meat and some veggies, and occasional fruit. No sugar or booze. I'm 63, 5'9" and 160 pounds. This the same wieght as high-school...except I'm stronger. I can do 20 pull-ups. I can run for an hour in the heat or cold without discomfort. This feels superhuman. I don't think I would be as vital or as happy 20 pounds lighter and weaker. I think Dr. Sinclair will probably live longer, but this intensity and power is too fun to give up. I guess is all about what you want.

[@prshr6145]

Keep up the good work!!

[@cytx6835]

hi, do you eat carbs or not at all?

[@riddlerhymes512]

@@cytx6835 I eat some carbs, I hit 50 to 70 or so. Nonstarchy veggies. I feel better and sharp on mostly meat. Those days it's 20 carbs. I can't keep weight on me with all meat. I also love activity. Just finished a season as a renfaire actor. So I sword fighting, dancing, etc. 30, 000 steps a performance. It's just too fun, not do.

[@drewbarefoot4428]

Same here! I keep telling my wife I feel superhuman haha

[@cytx6835]

@@riddlerhymes512 thx a lot for sharing! I feel tired and anxious a lot and im trying to find a diet that suits me so I'm willing to try. But again thanks a lot for your shared experience. What is your eating Window if I may ask finally ?

[@marcosnascimento4701]

Cold shower daily 30 push ups before shower Fasting for 36 hours once a week Trying my best to avoid bread and sugary stuff Meditation every morning Love the show

[@hata6290]

there is nothing wrong with bread :(

[@marcosnascimento4701]

@@hata6290 thanks for letting me know, to be honest I am trying to avoid carbs as much as possible 👍

[@dea1184]

B No b S

[@aristotle736]

@@hata6290 substantial quality bread is great .

[@jegelskerunited]

Almost the same Cold shower daily for 3 mins 200 push-ups or running 4 km before shower Meditation every morning for 10 min avoid carbs morning and at lunch Reading 30 mins everyday Love the show too

[@mikesolan8273]

Tony, all, I am mesmerised and astounded by, and in awe of Dr David Sinclair and what he has achieved so far. I've watched every interview with him and podcast I can find. Some of his interviewers ask him dumb questions or talk about out themselves a lot. By contrast Tony your questions are refreshingly relevant, intelligent and often unique and unexpected, but always absolutely valid. It's clear that you've read and understood his book. Some of your questions to David are so unique that I expect them to flummox him. But have you noticed something? Never does he “Um” or “Ah” or hesitate or give a vague answer. Every time he instantly returns a confident, clear and unambiguous answer, without fail. That speaks volumes to me, confirming that he knows the subject very deeply. When David’s information theory of aging is eventually proven right and generally accepted, I believe will go down in history as one of the greatest ever scientists.

[@BeYourUniquePotential]

How wonderful. Thank you for this beautiful session Tom. I found your vibes so sensitive and soft and warm. Looking forward to the next one. Waving to you with love, Marie-Louise from Cornwall, UK ❤

[@aaronellis6870]

I’ve been fasting for 1 year now and the results are mind blowing , I feel and look my best !

[@herenow2895]

You must be pretty hungry by now :)

[@aaronellis6870]

@@herenow2895 I’m speaking from beyond the grave 🤣🤣🤣

[@dimitrispetridis62]

How are you still alive??

[@phines9]

How long do you fast

[@aaronellis6870]

@@phines9 23 hours , I usually eat a steak with salad , yogurt with fruit , within 1 hour

[@ironmaidenfitness654]

Love love love Doc Sinclair. Thank you Tom for bringing him back!

[@kameaokalanikalota-uzia5985]

Who else fast forwards when Tim is proving just how smart he is too?

[@suzanne3639]

Ha It happens with many different hosts , especially on these anti aging interviews! Well put. I guess they too though have such an avid interest and have done some research! But we want to just hear the expert !

[@seokoes]

David Sinclair is one of the most influential person on the earth. i truly believe in his resesrch and have been fasting for months already.. feeling great

[@mariaelenabrostrom1747]

What two extremely knowledgeable individuals! A pleasure listening and learning from them!!

[@grammasgardenofideas5081]

TOtally fascinating. wowzers. a feast for thought, ps. i played back some of this at 75 % speed. really great.ty

[@ginas.6656]

This is mind blowing, so interesting, watched all til the end.

[@debasishborthakur2141]

Dr. David Sinclair is my real hero.. He is literally doing some extraordinary work..👍 Love from India 🙏

[@semaaral2498]

Dr David Says he is approaching to 50 in this interview this is old one but good to listen again To refreshing the old information.Thanks

[@dariandotzinski3100]

Tom, I don't have enough time in the day to watch all your videos and take notes! For the 1 week I watched you, I have stopped cigarettes, marijuana, alcohol, sugar and started exercising twice a day and this is only the beginning, I am on my David Goggins mode. You are a blessing.

[@daliab8493]

That’s great! But how come you exercise twice a day?

[@skyhigh999]

I did 😊😊

[@danerose575]

Congratulations, Darian!

[@skyhigh999]

please share thelink for the particular video you mentioned above .

[@anderander5662]

I have found marijuana to be extremely dis-motivating.....it makes me want to do nothing but procastinate, lay around and eat..

[@garyneeley4932]

The old theory he mentions is the Bowen Theory. It's the foundation of my life and recovery. It's worth the research 💯

[@jamesdigriz5449]

Tom, when making such video compilations from old material, please state it clearly in the headline, not to mislead viewers into thinking this is a new interview. I'm so happy I realized in the beginning this is NOT a new interview, so I saved almost TWO HOURS of re-watching an old material.

[@williammartin9450]

Nice, you just saved me two hours too!

[@VR12_13]

If he did that he wouldn't get viewership, plus there's some stuff we may have missed when we watched it the first time. And it's good to have a refresher

[@bysupriya]

Please Mention it’s old recap video …

[@jamesdigriz5449]

@@VR12_13 This compilation does not include all material from latest interviews with David Sinclair, not to say some material in this compilation is too outdated and putting new material right next to the old one, with subtle contradictions, makes it all confusing. Just watch the last 2 interviews with David Sinclair: one from January this year and the other one from 2020, they cover everything. Their combined time is shorter than this compilation, they contain more information and no outdated, contradicting material. That's the best refreshener.

[@georgitchkhaidze1127]

My friends and family often tell me that my predictions for the future are mostly negative and frightening. Once, a few years ago, I started thinking about it. As it usually happens when something touches our emotions, I had a dream that night. In my dream, I knew that I was dreaming of positive events that would happen in the future. Dream: First, our Xenia appeared in front of me, she was then about 7- 8 years old. She was holding a ball of light in her hands. Before my eyes she started growing up, changing, and I saw an image of a beautiful girl she would become in the future. A ball of light grew with her, while she continued holding it in her hands. Then, the scene has changed: I was standing next to Irina, and, even no words were exchanged, I started receiving information which conveyed the idea that even during our lifetime, it will become possible to extend our life once, and then once again. (I'm 53, Irine's 75.) Interpretation: I see this dream as quite direct and clear. The ball of light in the hands of Xenia symbolizes individuality. It was only after this dream that I began to search, and I learned a lot of interesting things about anti-aging, as well as about people like Ronald Klatz, Robert Goldman, David Sinclair, and others.

[@directsms-792]

Write me for more insights 👆👆

[@danastewart9281]

Others should include the Bible. God and his word make it very clear that we are to be healthy and live a long life. The world has taught us to become old & sick and live the lifespan that the world teach us to expect. Moses died at 120. He was not weak, stooped & had no dimness of vision. This is clearly stated so that we can easily understand what God has planned for us. 🙏🙏

[@wanetahw]

This is incredible! Thank you so much for this episode. Around 1:05, where David talks about storing all of humanity’s data in a test tube…🤯 I’m not understanding that completely. Where can I find more on THAT? 🥳

[@williammartin9450]

On the subject of aging and longevity, how come you've not had anyone on discussing the recent finding on fecal transplants from young to old mice? Seems like good science and I'm sure Dr Sinclair would have a perspective. Thanks for what you do Tom, knowledge is changing and empowering lives.

[@Soapgirl64]

Agree! That would be a great topic …

[@thatchessguy7072]

I’ve heard about something similar to this, it has to do with changing the microbiome forcefully, right?

[@Soapgirl64]

@@thatchessguy7072 yes. They take feces from a “healthy” microbiome and transfer it. I put healthy in quotations because they are still trying to figure out what that is .. not only for aging but digestive issues as well.

[@murrmurr765]

Tom is such a dork, a pretty good interviewer though! Really enjoy many of his videos.

[@SundayOlweny]

Top science thank you Dr. Sinclair and Mr. Bilyeu

[@MicahBratt]

I use to be addicted to glucose too. I would always get headaches and feel sick when I didn't eat enough. In 2012 I went on a strict diet that involved no sugar and low carbs and that broke me off my dependance on lots of carbs. Now I can go long periods of time without needing to eat and feel great.

[@directsms-792]

Write me for more insights 👆👆

[@jangyman]

Good content ...thanks for sharing. One pet peeve of mine is the broad use of the term 'carbs' in this and many other serious discussions to describe dietary items to avoid. If we use it to mean 'carbohydrates' then it's important to understand that carbohydrates are everywhere. I think it's very important first to, at minimum, distinguish between simple and complex carbohydrates (which includes fiber, starch, glyocogen, etc) in in-depth conversations. Many people, on what they call a 'keto' diet, talk about how their diet avoids carbs ...but what they are really avoiding is simple/processed/poor quality carbohydrates. It is quite possible to enter ketosis while largely ingesting complex carbohydrates, as many plant-based eaters do. I very rarely hear acknowledgement of that.

[@hata6290]

yeah starch is the best

[@NinaT940]

Agree. Carb is bantered around now in general use without being specific around what category of carbs. I eat a truck ton of vegetables and berries and don’t consider my diet low carb at all. I don’t eat potatoes for no other reason than I don’t like them. Much to the horror of my Irish father! I don’t eat heavily processed refined carbs. As stated my diet is not low carb. Your right about keto as many avoid all good carbs also so defining low carb is important to the listener. 😃

[@CindyMcAsey]

Very Interesting... oh how well I remember the resveratrol controversy!

[@directsms-792]

Write me for more insights 👆👆

[@Vshamann336]

It's tough but it's not that tough especially if you reward yourself in your eating window. I worked in a restaurant, fast food, and Culver's. And I did an 18-hour fast every day while smelling all that food cooking and I barely had a problem. But that's because once 8:00 rolled around I sampled every single thing in the restaurant within reason

[@Vshamann336]

I also worked out everyday on this fast and for a while I was running 6 miles every night, and this is after I woke up around 4:30 and want to work all the way till 5:00. So it can't be that hard, if I could do it. Granted I can wheel through just about anything I choose I didn't do it that way. Now I had to cut some cardio out because I'm looking to build more muscle. And I've been having mixed results with that and fasting. So far I found you can do it but you hit a plateau and it's hard to peekk past it

[@goldenratiogs4099]

Dr.Gundry had mentioned that Mitochondria will replicate itself with fasting and ketosis producing dietary intakes, like MCT and coconut oil, defeats the metformin intake

[@directsms-792]

Write me for more insights 👆👆

[@hata6290]

im sorry but dr gundry is a complete fraud. like, an actual scam artist

[@danastewart9281]

I would stick with the coconut oil!

[@cc1694]

Liked Tom's "who cares" face, when he heard "not for us , but for our kids"))))))

[@gretasutton]

Wow a stunning briliant minds🙏

[@MindDrip]

There's something very off about the audio. Can barely hear the conversation and when I turn it up the bass is way too heavy. Then you have the inline ad for your discord and it's wayy too loud in comparison 👎

[@Marksquire]

For me, being on a completely gluten free diet, NO oils (only butter, ghee, tallow), no fried foods, no refined sugar, no burned meat, no nitrates, and making sure I have all of the essential nutrients every day. Especially minerals. Our bodies don’t work correctly when we’re deficient in even ONE nutrient. I’m a huge Dr Joel Wallach fanboy. The man has saved my life.

[@RogueCylon]

Seek out real Olive Oil, not the store bought stuff. Best source of omega 3.

[@neilcave4527]

fascinating

[@coolguy8244]

Very interesting

[@ladonnabellavillalobos9627]

I actually met him about six or seven years ago at a conference or seminar where he was a guest speaker before he was on KZbin and I’ve been reversing my age ever cents I just turned 68 July 10, 2022 and a picture of me right there as recent no photo shopping nothing it’s not really that clear of the picture because I don’t need to Photoshop anything I feel like I’m about 30 years old I’m not sure how old I look most important thing for me was to feel younger be able to do more and help people

[@chromashift]

is anyone avoiding going rail thin? My father is on the low carb, IF, metformin kick & looks almost skeletal like Dr. Sinclair here; Dr. Peter Attia is another interesting follow, more on the protein & lean muscle mass as a health tool/marker.....

[@stevenh109]

Maybe you're comparing their appearance to the typical - or even the supposedly slim - westerner? Who says that even a BMI of 22 is natural? It might just be that it's less overweight than the others. Look up Hadza and Masai. How chunky are they?

[@hata6290]

if you're consuming enough calories, eating enough carbs/protein, and progressively overloading your muscles through resistance training, then you shouldn't have a skeletal body.

[@danastewart9281]

Skinny is an ugly word just as being skinny is very unattractive. Thin & skinny are very different

[@Winkmeister]

Please regulate the volume levels of your inserted promos so they're the same level as the program. Thanks

[@creamofthecrop5868]

What’s his thoughts on the new study saying that fasting doesn’t do much unless it’s paired with a calorie deficit assuming the calorie deficit causes most of the benefits and not the fasting

[@directsms-792]

Write me for more insights 👆👆

[@jamesdigriz5449]

This is a RECYCLED video made up of several past videos. Very confusing to watch, as there are constant jumps and a lot of inconsistency. Not to say it became almost 2 hours long.

[@catherineadkinson3581]

Sooo… interesting!

[@laurelmartone73]

Please interview Dr. Anthony Chaffee for the protein/meat/vegetables counter-argument.

[@nutech1810]

He's awful, haha, and nothing is based on research. It's anecdotal & cherry picked info. Mostly, boomers follow his bs. Who actually believes eating only meat is healthy long term? Lol Women are getting 2 periods now, & many are getting cholesterol deposits under their eyes. Sinclair is vegan. Use your head.

[@laurelmartone73]

@@nutech1810 obviously you follow Sinclair’s bs. Good luck with that. Btw, I don’t eat only meat, but I will NEVER be vegan, nor vegetarian.

[@jumpeight]

any thoughts on the MIND diet (combo of Mediterranean and DASH)?

[@umeshchhikara]

At 36 minutes - explanation of how metformin works on AMKP to initially poison mitochodria seeking rebirth/energy and then in the long run production of more mitochondria's to produce more energy. Correct? My question - when we talk about Zone 2 training or shall I say training to improve fat threshold; we are squeezing the mitochondrial capacity to its best depending on its health. Right? But then we persist with zone 2 training to improve the threshold and we do that very easily in a few sessions from my experience. Can we call this effect the same as metformin? Producing more mitochondria's to produce more energy to eventually improve fat threshold? Because the logic is same - stress the system. But since we have multiple energy systems, we must resort to a certain training that stress the mitochodrial capacity. Makes sense?

[@tenzindolma6266]

Apparently yes.

[@tommyfreudenthal8084]

Is the same session as some months ago?

[@Victor33]

With all the information in the world, I wonder what Tom eats and avoids

[@ligiasommers]

I am a super fan of David Sinclair, genius 🙏🏻❤️‍🩹✨🌹

[@Vshamann336]

Tom I wish you would check out the whole breatharian thing, and see if you can talk to anybody knowledgeable about it. I never thought till recently that they might be on to something at least, but now I do think that they're actually onto something. I don't know if they've never eaten but I do think their body is doing something like hibernation and a very small amount sustaining them

[@marisamarino7596]

I did a 31 day juice fast. No issues during the fast. The re-feed was hard on my stomach. Shorter juice fasts and water fasts are no prob.

[@mrmonay]

Juice fasts don’t make much sense …

[@marisamarino7596]

@@mrmonay well they have certainly helped with the autoimmune stuff I am dealing with.

[@summerofsais]

A juice fast isn’t a fast. Just do water next time. You’re constantly taking in sugar on a juice fast. Insulin spikes = no fast. Terminology aside if it’s helping you with your disease congrats. Give the water a try as well and you will more than likely see even better results.

[@marisamarino7596]

@@summerofsais I’ve done both water and juice. If you have ever seen Joe’s testimony in Fat, Sick, and Nearly Dead I would say juice worked well for him. Same with Chris from Chris Beat Cancer. I do not think it’s for everyone but a lot of people have had great results. I’m having great results from taking colostrum right now. I’m non functional by the 3rd day of a water fast.

[@maureengreen617]

@@marisamarino7596 I think the reason why you’re nonfunctional on a three day water fast is because you’re so juiced up on glucose.

[@daddu1983]

I have seen this interview last year but hereit shows 1 hour, Is it reloaded

[@hata6290]

he re uploaded the video :( not good

[@sailingmohican2767]

Honestly a 100% meat diet has made me loose 10 years in 3 months all medical issues went away ..and I go a day or 2 without eating ( just not hungry) then eat 2 to 3 lbs of meat and good to go again I don't have a sweet tooth anymore...i respect what your doing it helped me I simply condensed your info and determined only way was meat ..so I tried it and it is life changing 😌

[@drewbarefoot4428]

Yes. I’ve started adding organ meat to my diet and ditching veggies, I feel amazing! Been 4 months and I’m leaning into this hard

[@thatchessguy7072]

David Sinclair has commonly stated on interviews these 100% meat diets are high in amino acids and thus activate MTOR. This is like burning a candle at both ends, so yes you should expect to feel better in the short term by eating lots of meat. In twenty years… you should expect to have aged more than 20 biological years. Edit: actually, this is the very first topic they covered in this video.

[@tenzindolma6266]

Sorry for you. Animal proteins slow down and stop the DNA repair by some mechanisms. That's why Sinclair has quit his old nutrition style and moved on a 90% plant based one, for not long back. This is science brought up by recent studies.

[@sailingmohican2767]

@@tenzindolma6266 all animals defense is teeth and claws all plants defend by producing toxins and poison soooo I'm good 👍almost 30 years of wearing eye glasses now I don't need them, I have gained almost a inch in height back and my sugar level never crashes skin feels and looks 20 years younger I see zero bad side affects plus I naturally fast now average I eat every 2 days the one day I ate liver and tender loin and absolutely wasn't hungry for 4 days then had a taste for salmon..what's the point living a few extra years if your always cooking or going to the eye doctor 😀 A pice of beef jerky and some water and I can hike all day or enjoy life soooo it's a no brainer for me ..sorry for you your worrying about what I eat is raising your cortisol levels and that definitely shortens your life span😉try something new it may surprise you..

[@Lurksin1]

Sword of omen give me sight beyond sight!

[@yuliya9885]

I think the order of part is messed up. Great interview tho

[@michellerenee5028]

Volume would be ggggggreat!

[@melodysnook8057]

Can someone tell me if they can give metformin to type 1 with good results

[@donotmissDutch]

For Tom: suggestion: don't wear glasses just to look intelligent. Or, if you really have bad sight, wear a light colloured 'montuur' (netherlands lanquage).

[@albertodelrio5966]

Is it an older interview?

[@herenow2895]

Would you want to live forever ? Are you frightened of dying ? I reckon that outliving your friends and family would be quite a lonely experience.

[@avwel3827]

😂😂good one!!

[@danastewart9281]

Perhaps not forever, but I would like to live a high quality life for a long time. I am 56 and have an 18 year old son. So, yes I want to live a long life and also be healthy enough to enjoy it and not need care or to be a burden rather than a blessing. According to the Bible, the lifespan that Gods has prepared for us, 60 is middle age. Moses died at 120 with no weakness, was not stooped and had no dimness of vision. The world has taught us that we must become “old & sick” and die before what should be our time. I choose life!🙏🙏

[@herenow2895]

@@danastewart9281 - Well said.

[@jeremiahsams2848]

@@danastewart9281 👏🏿👏🏿👏🏿

[@sylviashomer2312]

Is there any chance of finding cure for muscles diseases in any way

[@Patogilvillalobos]

Serotonin is first? Level 2??

[@alexmannen1991]

so shortterm usage of it will make u less lethargic and train ur cells to be more efficent?

[@directsms-792]

Write me for more insights 👆👆

[@kerrietinsley6462]

Resveratrol?? Is this a supplement to take - obviously not consuming more red wine?? Where is the seller to access please 😊😊

[@ragetotheend]

Why is this a repost of the same video? Thought it had new content...

[@danastewart9281]

Wow! How complicated. The time wasted on living like this will age you as much or more than living sensibly. Two sentences to live happy & healthy. “Moderation in all things” and “As a man thinketh so is he” 🙏🙏

[@andertomsen]

Then go try heroin , in moderation of course ;)

[@PerthesExercises]

@TomBilyeu, Interesting how you reschuffled this interview and republished it pushing the story that you had in the introduction about the Poker dealer having a stroke and then dying afterwards, to the second half of the video. Was this to minimize the attention to this as many people will comment theorizing that this was likely a Backsine related death and not related to normal aging? Or just to avoid KZbin algorithms demonetization? I’m curious to hear the reasoning, ‘cause initially I thought this was a follow up interview but then I thought it was an extended version of the interview, when it was just a reschuffed version with some commercials in the middle. By the way this was a great interview, that’s why I didn’t mind watching it twice.

[@ladonnabellavillalobos9627]

If I could talk to DAVID I would tell him I volunteer to be in any clinical trial when he needs humans I would be honored to volunteer my basic thing is not actually to look younger even though I do I can’t believe how much younger I am a walking talking miracle seriously I am I have beat the odds so many times my first experience was when I was only a couple months old when I got my skull cut open where my mom said you could see my brain I’m glad I don’t remember it but I know it’s there in my mind somewhere and then I have 100 stories or so of my will to live I fight to live I was born with congenital scoliosis I have been fighting against that my whole life so I won’t be humped over and I got Covid if that’s what it was in 2018 January 1 is when I ended up in the hospital I believe they were calling it coronavirus or covet Sar some I don’t know but it was bad it was horrible I just wanted to die and go to heaven but the Lord had different plans for my life easy when I was in my early 20s I moved by your Health food store I fell in love with the way you can heal your body with your mind with faith and the will to live and HELP from David Sinclair yes there are no words created yet to explain how important this gentleman is how wonderful he has how loving he is and how caring he is for humanity You’re probably not gonna like this but the only other person that I think really cares about humanity that I’ve had the privilege of meeting is Elon Musk but that’s a whole different story either love him or hate him

[@superhuman5857]

Is there a book on this

[@Shemalinski]

Audio is too low

[@dynamicalan]

Cooking polyphenols deteriorate when you cook them and Extra Virgin olive oil does too: There is sugar in everything so what is the limit so the body will start making it's own sugar - Carbohydrates should be limited but a tortilla only has 50 carbs so is that too much.

[@Myrslokstok]

Cant we try to make a new set of theets!

[@carloscarion1748]

Yoga should be done before doing any sort of walking or other physical exercise, as prescribed by the old yogis, and yoga philosophy that also includes your pranayama, or breathing exercises, just saying. I do enjoy the article though

[@kerrietinsley6462]

What is NMN??

[@violetanastassova3425]

can hCG help by pushing fat in the blood stream and one wont feel extreme hunger?

[@tahsin95]

Damn, the guy is 50.. and every year he looks younger.

[@carinazegarra6289]

Is that a Steve Aoki poster in the back 👀

[@frankerororo]

How about blood donation?

[@joe3876]

This is a re-upload right?

[@hata6290]

yeah :(

[@sviniata]

why there is no more content from David for an year ? what's up with the research ?

[@guy.incognito]

isn't that the same interview uploaded six months ago?

[@directsms-792]

Write me for more insights 👆👆

[@brendasiron6350]

I have a mutated gene that will not let my body methalate. So what does that do to my longevity?

[@oneluv11]

so if we want to build muscle (eating lots of protein), it will shorten out lives?....how do we build muscle then?

[@chromashift]

look into Dr. Peter Attia podcast; another longevity enthusiast, one into building muscle & eating protein. having muscle/strength is vital as we age;

[@oneluv11]

@@chromashift so it is possible?

[@chromashift]

@@oneluv11 it may be not only possible, but vital; I don't have a link offhand, but he has a cast here on youtube discussing this very subject;

[@hata6290]

@@oneluv11 just eat a decent amount of protein, and a lot of carbs. boom, youre building muscle.

[@oneluv11]

@@hata6290 high mtor still tho no?

[@VRCM_Skywarn_XUSA]

Id like to be able, to grow teeth back. That would be wonderful. I miss whistling...

[@Patogilvillalobos]

Metaphormin 1 day when we dont excercise . How does METAPHORMIA SPELLS?? Thankuuuuu

[@thebandbband]

Metformin not mataphormin

[@Patogilvillalobos]

@@thebandbband thanku😜

[@Patogilvillalobos]

Methylation?? How donu write ir spell it? Sorry but Spanish is my mother language

[@kencarey3477]

What exactly should we eat? I am high carb vegan I thought that was healthy

[@hata6290]

OMG thats literally the healthiest. youre doing good :) as long as most of those carbs are in the form of starches

[@kencarey3477]

@@hata6290 thank you! I'm 65 and getting ready to hike through grand canyon rim to rim

[@tenzindolma6266]

You do good. Sinclair is on 90% plant based since little time. He switched to, after studies showing animal proteins are stopping the DNA repair .

[@kencarey3477]

@@tenzindolma6266 thank you! There is so much hype about keto diet. I think it's better to fast into ketosis instead of eating all the animal fat

[@johntorrance7399]

I have been fasting, exercising and taking NMN, resveretrol. I started metformin but am concerned about the side effect of decreased testosterone in males that can cause significant sexual dysfunction and have stopped it. Has this been noticed in the anti-aging studies

[@angelicannihilator]

Don't take Metformin, even though Dr. Sinclaire takes it for anti aging purposes. Common sense tells you that it's a synthetic pharmaceutical substance that should not be in the body. Take berberine instead. Also do not take a daily baby aspirin.

[@MoMindSetCrypto]

Go for berberine instead of metformin, advice watch some youtube videos on berberine first and then decide.

[@abdirisakadeys458]

Lowering stress

[@foxclover6]

It's predominantly fasting.

[@HealthyLife4Me]

Hormone balancing, exercise a good diet and never becoming mineral or nutrient deficient..

[@BibleBreakout]

When was this recorded? He says he’s 50 in this interview but he’s going on 53 now.

[@jamesdigriz5449]

This video is a compilation of several videos from the past, and is thus very confusing to watch!

[@bruh-bg5gs]

Stop with the in-video ads. Unless you intend to pay for my premium KZbin account. To everyone else, David Sinclair does the same video with Andrew Huberman.

[@oliverclinton5145]

The Market has been pretty bad until today it decided to surge. Everybody was Practically Crying then. It kept dipping. That's what you get when you feel you can navigate the process on your own. Big thank to Alexis caballero. I'm not bothered with how bad the Market is because my assests are insured due to her advice and I still receive my profits

[@user-kr3vi6zv5r]

Could you kindly minimize your interruptions and allow your guest to speak more?

[@clairea-t7045]

Deforest Kelley gave me a pill and I GREW A NEW KIDNEY! Sounds like Star Trek to me. Who Knew!!!

[@Patogilvillalobos]

Metaphorm?? ( Creates mitocondria?

[@robertfleischer6068]

Metforman

[@JarmoSyvari]

👌🙂 🙏

[@hoodbutterfly7221]

I wonder if David knows something about hairloss and how to reverse it…

[@yuliya9885]

Yes he mentioned that in his other interview

[@555Trout]

What is wrong with aging?

[@Bankai90]

Noone rly cares about dying in your 80's. But for a loooot of ppl life gets fkd in their 40's and 50's due to the body starting to malfunction. Be it your back not letting you up. Be it insomnia. Be it a blood clot and losing your leg. Be it cancer or heartattack. Be it a stroke. Although people live life till 83, often 10years+ are lived in absolute misery, and for many that can be 30years+. How to avoid that is important

[@555Trout]

@@Bankai90 Virtually all human beings who ever existed, billions and billions, didn't make it past 30. Anything after 40 is pure bonus of modern technology and abundance. It would do people well to frame things correctly.

[@Bankai90]

@@555Trout what the hell dude XDDD

[@555Trout]

@@Bankai90 Yeah, that growing up thing sucks. Realize you are bounded by extreme limitations at all levels of existence. The primary one being you will absolutely die, and die fast. Life will be over in the blink of an eye. Obsessing over aging is a tragic waste of today, the only thing you have. Wasting today's energy for more tomorrows is a treadmill of idiocy .

[@Bankai90]

@@555Trout dude human lifespan has been pretty much the same when we disregard environmental issues. Average lifespan is something completely different when we think about 500k or even 2k years ago lol. So it's true that most humans did die at 20-40, but not due to biological limitations (unless you count viruses/bacteria)into it. The human body is capable to live 70-90years old on average and that has been the case for tenthousand of years.

[@wirefrost3287]

Me taking notes : hmm nice nice, interesting. Also China taking notes: hmm nice nice, interesting.

[@hata6290]

LMAO

[@dinosemr8141]

💖❤️💖🙏❤️💖❤️

[@chickensandw1tch]

52:20 💀💀 1:01:00 legendary🔥💯 1:07:00 intense🗣️ 1:08:05 real 1:28:50 🙌🏻 1:31:40 prank💀