Translation

NDSU Virtual Cell Animations project animation "Translation". For more information, see vcell.ndsu.nodak.edu/animations
Translation is a key process in biological lifeforms. It is this set of events that transforms the code contained in DNA and later mRNA into the proteins necessary for cellular life.

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Who's watching it in 2024?

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me!

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Me also

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[@MuhammedTheunknown-fg7qp]

And realizing it’s lgbtq

[@icebubbles44]

I tried to read this in my textbook and had no idea what the HELL it was saying, you helped me get it in 3 and a half minutes. Thank you!

[@jesuschrist9712]

hahahaha same here

[@jesuschrist9712]

still hasnt watched the video yet. my hopes r high now

[@Theonemen5]

i think the problem with textbook explanations is, that it is quite abstract to be described with words. So the animation is very helpful

[@zakariajony4193]

yeah. excellent explanation.👌👌

[@profx6260]

Hahaha. Yes same here kind-off 😂

[@clvsidy]

how does my body know how to do this and my brain can’t 😭

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That's the saddest part of life 😢

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[@sayonara2359]

This is why i love biology. So much is happening inside our body and we don't even realise it. I read these process multiple times in my book and then watched the animation. It really helped me thank you!

[@POPsongsADDICT]

clearly explained, but with a few missing points, so it definitely helps a lot in my revision. 1. eukaryotic initiation factors first need to bind to the small ribosomal subunit to position the initiator tRNA properly at the P site. the later dissociate to allow binding of the large ribosomal subunit 2. the release factor adds a water molecule to the polypeptide to terminate translation and release the polypeptide chain 3. the amino acid is bound to the tRNA via an ester bond 4. peptide bonds are formed between the amino acids in the growing polypeptide chain 5. the entire process requires the hydrolysis of ATP

[@abdyer2009]

ATP Hydrolysis is necessary, but prior to the steps they are showing. The energy used from the hydrolysis of ATP is captured within the ester bond of tRNA to the amino acid.

[@ishikabiswas6511]

POPsongsADDICT that was the very first step called charging of tRNA but its not added in the video

[@doreamonunofficial848]

Yes some enzymes along with GTP are not mentioned. 😌

[@rahmahdalhat8484]

Thank you

[@filzuhilal3225]

@@doreamonunofficial848 * ATP

[@thediabolicalone719]

11 years old video. I was 7 years old when they uploaded it. Now here i am watching it the night before my A Level biology exam :) Wish me luck :)

[@amanupadhyay8765]

awesome.... no stupid useless disturbing background music great explanation.

[@izgit]

And no annoying accent

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[@PriyankPatel-ji4en]

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[@rockard94]

I found out about this video while in college. Helped me pass bio2, and now using it for biochem. Thanks, very helpful

[@dakotahbeck2223]

+Julien Prégent im watching this video and im in 10th grade honors bio and we are doing this but yes super helpful! XD

[@ilyanikitin5271]

+Koda Beck how are you in 10 grade and in honors bio

[@alyannanedlei2]

Im like in the 8th grade and this is basic Bio for us

[@eVill420]

@@alyannanedlei2 well congralations you learned a university level subject already

[@CinnamonToast]

This video is only 3 minutes long but it does such a better job than pages worth of textbook or 15 minute long videos. Thank you so much for making this, translation makes so much more sense now and it's actually way less complicated than it's made out to be in class.

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All joking aside this was a beautiful video 10/10 would watch again

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AllTimeSnowman I CANNOT HELP IT I AM WATCHING AGAIN

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@@terigonUSAS12 I watched this like 10 times, a true masterpiece.

[@kylesznoluch5924]

This video was the first of many I've seen that actually had a easy to understand depiction of the continuous process of making proteins. Wonderful.

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Man this video is fucking majestic and glorious as fuck. 10/10 would bang.

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youre god damn fucking right this video is fucking gorgeous, i'd fuck it with a 10/10 fuckin A rating

[@thesockinseokjin9663]

The process seems so long when I read it in the textbooks. So, thanks for this video! Very helpful!

[@davekahat]

they did leave a decent amount out (GTP expecially) but its a great start!

[@mangastrangeryoh853]

Wanna add what they left out? You would also be a lifesaver thenXD

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Hey Army ...

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@@sameersachan8427Rs.6000/yr. Gov. college still can't able to get this from books.

[@nazbinbegum6245]

Wait this was published 15 years ago?? This is so helpful thank uuuuu

[@blairw1695]

This plus the transcription video have helped so much. I’m a visual learner so seeing this in an animation actually made me learn the material. My prof is the most monotone person Ive ever heard, and basically just tried to explain it all in words.

[@nickgrqlkimd21]

Probably the most accurate and easy to understand videos about biological procedures on KZbin thank you!

[@user-zainab2004]

i was crying because the translation process was very difficult in the textbook , i was feeling like i will can't understand anything whatever i tried , i really feel happy because I found your talented channel you are helpful ❤️

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@asimnissar no it's not 💀💔 This animation movie saved me from failing ~✨

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@asimnissar i thought so too 😂

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this is fucking beautiful... fucking amazing

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Truly fucking astounding.. fucking marvelous

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Are you a graduate now?

[@shambhavikumar7077]

I spent an hour studying this from my book but couldn't imagine well. But damn this video explained in to me within 4mins.

[@willkayal3710]

This is the best video on translation ever! Maybe for more advanced students talk about how the bond between the amino acids is a Carbon-Nitrogen covalent bond. Also, something to add is that when translocation happens which is when the Ribosome moves down the mRNA it uses GTP as energy. When the first tRNA binds to the initiation codon it also uses GTP. When the amino acids are bound together it uses Peptidyl Transferase. A polysome is a single mRNA strand with all of the multiple ribosomes translating it at the same time. The signal on the end of the new polypeptide tells the ribosome to deliver it to the ER which is then post-translationally modified and edited.

[@jengaughan9778]

I do a level biology and none of this was explained at all, not even in textbooks so I was very confused as to why the tRNA was even needed. I was also never told that the mRNA is between the sub units, this makes it so much more clearer, thank you!!

[@oluwatosin1936]

This just saved my life. Thank you so much!!!!

[@latifahtribuanadewi9408]

Amazing !!! Love it so much.. thank you for beautiful animation

[@rimeln6443]

i

[@MikeBassil]

Clear and simple, and thanks for explaining the 5' 3' directionality! No mention of the proteins involved (such as peptidyl transferase which is what merges the amino acid of the A-site to the polypeptide of P-site), but a very nice guide to the overall process!

[@summereligon9545]

waaay better than my lecturers at medical school!

[@missrosito]

Such a great video - simple and explained everything clearly and concisely; what very student wants. Keep making these :)

[@ropamazemo9030]

13 years ago Im still watching it and its still helping 😭😭😭😭

[@ronaldbernaldez2383]

What

[@SPineapple29]

Thank you so much! I’ve been staring at countless paragraphs and diagrams and not understanding translation, and this video helped a lot!

[@assirikrist8709]

Good video short and very understandable

[@echomythoughts]

Studying for my test right now and this helped a lot! Thanks! :)

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atb

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After searching all other complex videos on KZbin, I finally found this heavenly awesome video and got what I needed ......thanks...

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I have to say, I watched this video a year and a half ago for my first college Bio class and loved it. I am taking a similar class now and when we discussed it in class I was hoping I would find it again- and I did!

[@altair2594]

grear work.. our teacher should try this in the class!!

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BLESS YOUR SOUL.

[@rosejennie6307]

After 15 year I'm hear for watching the video..! And thx for helping us📚🔬👏🏻

[@BloodyTam6]

They write it so complicated and hard to understand in books,and look how actually simple it looks on this animation

[@aileneingabire10]

thank you so much this was very helpful

[@xxVanos]

Trust me better late than never! I love watching these videos and paraphrasing the contents to suit my exam questions :) Images in lecture notes help but seeing them actually MOVE is so much better! :D

[@Tihgjk]

i was crying with grief after reading the textbook and now I'm crying from happiness

[@sfashaikh1187]

This is one of greatest video i've seen in my whole life.

[@SwapnilSuman]

Excellent for biology students!!

[@biologyviii677]

best simplified, informative, soothing, well explained animation video i have ever seen. it was produced in 2008!

[@nitupandey7534]

When studying from textbook... I found this so difficult and uninteresting... after struggling for a few days... Idk from nowhere it came to mind to look for a animation video for this process...and trust meh this one is the best... it's really helpful.. thanks again ❤

[@Coolarj10]

AWESOME video. Thank you so much! This was so well explained - our professor should just use this video instead of showing us lecture slides.

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Wait, aren't you that guy who made a liquid cooling PC guide? World is so small

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I am from India and targeting the neet exam which is basically a medical exam.......this video helps me more to understand the concept very clearly and sharply in a very Conqueised manner......So, lot's of love from india to this channel and i hope you will gain more and more subscriber and basically the translation is one of the most difficult topic as far as i know and many indian Neet aspirant r facing to understand this topic so your teaching method with 3d animation is just amazing😍👍🤩😍.......hope everyone will understand.....

[@Medico_alian]

Same

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God bless the people who made this!! saved meeee big time. Textbooks, professors, wikipedia, none of it really helped. Except this amazing video.

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THANK YOU! After hours of Kaplan Biochem, Doctors in Training, and essentially every other resource one can use for the USMLE Step 1, this topic still gave me fits. Your video changed that. God bless.

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I GET IT NOW

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wow thanks to this video, I will pass my test!!!

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Thank you so much, this has been so helpful. Please never take it down!

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This was very amazing, thank you so much! 16 years later and still helping students around the globe

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[@mohamedoun6094]

The most complicating part in all molucular biology 😭😭😭😭

[@Maya-yu5nl]

The whole animation of this video is just so satisfying to watch plus the concept is explained so beautifully.. never understood this in class and now my mind is blown lol

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Id just came here to thank you. If i hadn't found your video 5 years ago, I would have failed high school

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THANK YOU U JUST SAVED MY BUTT FOR MY BIO TEST TODAY. I DIDNT GET ANYTHING AT ALL.

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How are you in college and still play Minecraft

[@Matrex794]

Praise to Jesus Christ!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

[@ClaraL27]

learned translation from this video in 10th grade and it's even a great refresher in college level bio! Will always visualize translation this way thanks to this perfect video!

[@yragg96]

Really good presentation. Finally, I understood the translation process. Thanks guys!

[@crubs83]

Is this the protein produced by the hypothetical "gay gene"?

[@jcmjub]

Thought so too!!! Hahaha

[@ImTehPetex]

why is the protein gay?

[@Sarmad.S]

.LOL😂😂😂

[@lomlkat99]

this is the best video about translation on youtube this was so well explained OMG

[@blackfriday9460]

Thank you. Easier to understand than just reading my textbook

[@songbird6445]

I share this video with all of my intro bio students and it is truly a God-send, as is this entire channel.

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Why your voice is so awesome. Jokes apart! Thank you.. You made everything so simple

[@hameedullah3555]

finally i found such a fantastic animation video about the topic after searching an hour . really admirable sir keep it up.

[@tysonpop19]

THANK YOU!!! This made so much sense and the visuals really helped

[@darccestdesaireh]

Look at the mind blowing graphics. Hats off

[@whalien53.mp484]

Even this video is not detailed, it helped me to understand the basis of translation. Thank you❤

[@saraborowiecka5608]

It seemed to be so difficult in Cleg's biology textbook, but thanks to this short video, I quickly grasp it!

[@eunkyungkim6365]

Just enough to understand the general concept! Thank you!

[@user-iz4jy3ph4o]

Wow, very nice. I understood the process in a simple and uncomplicated way. Following you from Iraq 🌼

[@teejohnson8720]

This video made so much sense! Thank you!

[@NonmetalAlkali]

it amazes me that this simple animation makes more sense than my AP Bio textbook does

[@marwaatef27]

Like I can't thank you enough for this TTTT sometimes just understanding the bigger picture (like what you did in the vid) is so much better than reading all those complex terminologies in text books when I don't even know What the hell is happening !! AMAZING VIDEOOOO!

[@evan-yifanwang6938]

IT EXPLAINS THE PROCESS SO CLEARLY! HELPS A LOT!!!!!!!!

[@NandanKumar-re2it]

Brilliant , precise and comprehensible explanation. Well done.

[@kileymcal]

- translation is the synthesis of proteins - translation initiation begins when the small subunit of the ribosome attaches and move to the translation initiation site - tRNA contains an anticodon which complements the mRNA codon (first is typically AUG) - the large subunit combines with the small subunit to make the P site and the A site - the first tRNA occupies th P site, the second tRNA enters the A site and is complementary - the first tRNA's protein is transferred to the second (linked) - the first tRNA exits - the ribosome moves along the mRNA - when a stop codon is encountered in the A site, a release factor enters and translation is terminated.

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thanku "christiana johnson" for making a amzing animation....u cleared my doubts...god bless u

[@tulen007]

Thanks for all your vids ndsuvirtualcell - the best!!

[@Loussinthesky]

Thank you for all your videos!!!!

[@joanagomesdias5558]

Such a great video!!! Well-explained, easy to understand and all of that in 3min30! Thank you so much, very helpful!!!

[@adityalohia9605]

thanks a lot ,i found many videos but they were unhelpfull for me with long durations and then i got urs with the best explanation 😉😄

[@lenapetrovic7094]

Thank you, beautiful human being who made this video, thank you.

[@tarit9mondal]

After the 5 years of study now I get it in 3 mins. thank u..

[@PeaceOfMind_999]

Thank you for uploading this

[@mathildeblanche5126]

3h de travail incompréhensibles résumées en 3 minutes... merci !

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Est-ce que je peux aller aux toilletes

[@ajaykumarsingh702]

This was so much help to me. THANK YOU so much !

[@tatianaharvey8170]

Really concise and to the point. Thank you so much!

[@alexiskowall]

You guys make the best biology videos !

[@lelijkebaas]

Overall a nicely made video. Chemically, the transfer mechanism as cartoonized here, doesn't make sense, though: the peptide chain does not dissociate from the tRNA in the P-site and then attaches to the tRNA in the A-site. It's the amino group of the amino acid in the A-site that first attacks the carbonyl group of the amino acid in the P-site, forming a covalent bond in a tetrahedral intermediate, then forming the peptide bond and simultaneous breaking of the bond to the tRNA in the P-site.

[@t-rexhsuki3206]

Since I'm a spatial learner...i found this video very useful and understood the concept very well...thanks

[@amyjoyeepun]

@mdsuvirtualcell, Thank you so much, this really helps me understand translation in molecular genetics. I feel more prepared for the DAT now. Just a suggestion, it would be nice if you showed the termination processing in the transcription video, how the okasaki fragments are glued by DNA ligase in the lagging strand, as well how the GC rich region ends the fragment, introns are removed, exons spliced together, and addition of 5'methylated cap and poly-A-tail to 3' of mRNA in eukaryotes.

[@SayHashtag]

absolutely helpful! I have a test tomorrow and I couldn't understand this! thank you so much!

[@BrBilal]

Thank You NDSU Animations Project!

[@tahzibyafi7197]

That was awesomeeeee!!!!! Thanks a lot to the person who made the video