TWiV 1119: Gene editing latent herpes

TWiV reviews viral shedding and antibody responses of men with acute monkeypox virus infection, and gene editing for latent herpes simplex virus infection reduces viral load and shedding.
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[@LisaMartinez-ri6ve]

Well I am pulling up Angela’s pick up the week. Just finished watching TWiV and now she peaked our curiosity with her pick😎Thank you TWiV team . We enjoyed this episode.

[@s.f.pharm.d.1197]

Vincent; “Bravo” on that clear,concise,& concrete (on-the-spot) explanation of Herpes latency/activation.

[@frogsong100]

"The WHO declared smallpox totally eradicated on May 8, 1980." "The basis for vaccination began in 1796 when the English doctor Edward Jenner noticed that milkmaids who had gotten cowpox were protected from smallpox. "

[@Jason4Hope]

Helpful towards my virology research endeavors. Thanks for the information you're sharing here.

[@stormwalker321]

Fascinated by Rich's overview re smallpox..(had the scratch vax as a kid...)...,...and all Vincents info regarding HSV/ as well...GREAT show everyone, thank you ! Just re-read Never Cry Wolf ....great book!!!

[@mkilptrick]

Angela's pick is really interesting. Really makes you think.

[@afterbabel]

COVID and other viral infections can also cause HSV-1 and HSV-2 to reactivate

[@nycbliss]

Cool show- thank you! I always learn something. Of course now I want to hear that MPX story…..

[@christopherrobinson7541]

Its a triple XXX story and not for KZbin.

[@cynthialeech2507]

Thanks for this timely information on Shingles. I was 2 weeks away from appointment for Shingrex vaccine. My flare up seems to have occured in T1 area. I have never felt so much continuous stabbing pain in my life. I'm pretty tough having birthed an 8lb 3oz baby non-medicated. Get the Vaccine! You don't want to get Shingles. Thank Gd for antivirals and Neurontin.

[@highlandbob2470]

It’s just a little rash, not.

[@redhen689]

I was in Sweden for Midsommar (summer solstice) ☀️ 2 years ago. The sun would set about 10pm, and rise about 2am. It never got dark. The sunset lasted for hours and transitioned into a sunrise. The sky was beautiful.

[@silentrunner3067]

Got 1st small pox vax as a toddler in the late 1950s, was re-vaxed in late 1973 before a college trip to Europe. Still have the yellow paper international health record that went with your passport.

[@GertvandenBerg]

The yellow book also gets used for yellow fever vaccines... (And would probably have made sense to use for COVID-19 vaccines instead of inventing a different system...)

[@LokkhadkaLokkhadka-sn1pi]

What is the current epidemic of simplex virus in the US?

[@jenniferblessing3086]

I'm grateful to have come across you doc oromi on youtube channel , I'm now free after I used the medicine you sent me, having Herpes almost ruined my life but I'm happy today after I used your treatment.😚❤

[@liuwang2201]

Acquired immune deficiency syndrome, or AIDS, is an autoimmune disease AIDS is not a typical autoimmune disease. There is currently no cure for autoimmune diseases

[@sciencefliestothemoon2305]

Caused by the human immunodeficiency virus

[@JillKnapp]

"So you have to put them [mice] on skis and put 'em on the top of a mountain and maybe they would reactivate." 😁😁

[@42meralee]

Coy dogs, coyote cross, are very common.

[@Gina-dn6xm]

I have been diagnosed with reactivated Epstein Barr. I have also been diagnosed with ME/ CFS. It's all just a big guessing game because mono has never really been studied? My physician said there is no treatment for reactivated Epstein Barr.

[@tunneling-nanotubes]

The Bateman Horne center and ME-pedia have helpful info for patients and doctors.

[@Gina-dn6xm]

@@tunneling-nanotubes Thanks

[@kmook76]

There are studies showing long term antiviral treatment can reduce the latent viral load for EBV which would be very useful for people who have frequent reactivations and or MS, ME/CFS.

[@Sam-wu5ry]

I didnt do a DISservice in this comment section😮😮😮😮😮😮

[@LokkhadkaLokkhadka-sn1pi]

85% of people who have HSV DONT KNOW

[@liuwang2201]

is long-coved a (Lytic Cycle/Lysogenic Cycle) similar to herpes

[@frogsong100]

If that were the case, it would have been discovered in autopsies. And, there were countless attempts to find a hiding place.

[@tunneling-nanotubes]

​@@frogsong100 Got any citations with properly preserved and assayed samples? Hours after death that samples were preserved and method?

[@frogsong100]

​@tunneling-nanotubes - Anderson Cooper did a fantastic 60 MINUTES on CNN in Nov.24,2020 which focused on Long Covid. Here is an excerpt: [ Dr. Mary Fowkes: Because we don't know anything about this disease- an autopsy is the most useful. Because it will help us determine how this virus is actually making people sick. As head of autopsy and neuropathology at Mount Sinai, Dr. Mary Fowkes examined more than a hundred people who died from COVID. Early on, she was stunned by how widespread the destruction was. Anderson Cooper: So people think of COVID as a respiratory illness. But you're seeing damage all over the body. Dr. Mary Fowkes: So there's damage in lung, heart, brain, kidney, liver. Dr. Fowkes told us some of the damage could be caused, in part, by the amped up immune response, but she also spotted something else. Dr. Mary Fowkes: We saw small and very microscopic blood clots in the lungs, the heart, the liver-- and significant blood clots in the brain. Anderson Cooper: Is that something you expected to find? Dr. Mary Fowkes: No, not at all. Nobody's seen it like this. Blood clots can lead to strokes, which Dr. Fowkes frequently found in the brains of covid victims. ]

[@frogsong100]

​​@@tunneling-nanotubes- It is common sense that if the hiding place of herpes virus was found, certainly the search for the sars...cov...2 hiding location was conducted so that the Long Covid problem could be solved. Right?

[@frogsong100]

​@@tunneling-nanotubes- I gave a long reply, but it was removed by MicrobeTV or Russian trolls.

[@liuwang2201]

slip errors in mRNA vaxed, lead to unwanted prions ?

[@frogsong100]

Where in Russia do you live, troll?

[@christopherrobinson7541]

Nonsense.

[@RTew021]

A historical use of smallpox was the presentation of blankets by European settlers to Native Americans, blankets that had kept European smallpox patients warm until they recovered or died. This was of course part of the European effort to eradicate Native American peoples so their land could be taken.

[@frogsong100]

I doubt this story because those handing the blankets out would get the smallpox. As I recall, the blankets were infected with something like chicken pox, to which the Caucasians were immune from previous personal and ancestral infections. The intention was genocide, so thanks for reminding us.

[@frogsong100]

Wrong. .... It was the British military that did the crime. "The British give smallpox-contaminated blankets to Shawnee and Lenape (Delaware) communities-an action sanctioned by the British officers Sir Jeffery Amherst and his replacement, General Thomas Gage. “Out of our regard to them … we gave them two Blankets and an Handkerchief out of the Small Pox Hospital. I hope it will have the desired effect.” -An eyewitness, quoted in Elizabeth A. Fenn, Pox Americana: The Great Smallpox Epidemic of 1775-81

[@frogsong100]

Troll hacker. Should be blocked. Troll deleted my fact that is was the British soldiers who gave out the Pox blankets.

[@RileyKing-eo4xj]

Hs

[@Godstime-z9h]

Am so delighted to call you my doctor, I never believed I will be free from Herpes, all appreciation to you " SR HEAL US " on KZbin, indeed you are a life saver, I’ll keep on sharing this testimony all the days of my life.🎉🎉🧬🧬🧬💞💞💞💞