What's the role of Vitamin K2 in Chronic Kidney Disease and Dialysis?

In this video, we look at the role of Vitamin K2 in kidney disease and whether or not you should supplement with it?
0:00 Intro
0:25 Kidney Disease and Heart Disease link
1:25 What is the role of phosphorous in kidney disease?
2:05 Vitamin K2 basics and role in kidney disease
4:45 Absorption of K2 in CKD
6:11 Why MK-7 is better than the other forms?
7:00 Safety profile of K2
7:36 Take home message for K2
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DISCLAIMER:
Disclaimer: The information provided is for general knowledge and is not a substitute for individual medical advice. All viewers should consult their physician before starting any medical program or treatment. Any action you take upon the information that you find within this content is strictly at your own risk. Never disregard professional medical advice or delay in seeking it because of something you have heard on the SELF Principle KZbin channel, Podcast, or website.

[@SELFPrinciple]

Thanks for watching. Be sure to check out the Vitamin K2 overview video that will explain all the benefits. kzbin.info/www/bejne/o3mQY6GqYtRloLs

[@pingshop8829]

If Vitamin k2 or (Menaquinone -7) are good for have kidney disease or high creatinine level or it is bad?

[@dpjbdpjb]

K2 ok with blood thinner called Clopidogrel 75mg? I just had stents put in my heart

[@k2d338]

I have been taking K2 and D3 for over 4 years now. I am 79. About 6 years ago I had a serious heart attack brought on by arterioriolsclerosis. I needed 4 stents to survive. I was placed on blood pressure medication, statins, coumadin, etc. Since taking K2,D3 I have stopped taking the BP meds, statins, etc. I have discovered that many doctors do not know about the benefits of D3,K2 supplements or simply do not want to recommend their use. I personally take 30,000 IU of D3 along with 300 mcg of K2 on a daily basis. My blood pressure has dropped significantly to 120/75 during my use of D3,K2. Please note that it is very important to take K2 while taking D3. Just my personal experience. Hope that this helps somone out there. Note that there are many studies and reports available on line on the taking these supplements.

[@thomaslevine405]

They don't seem to know how much K2, but 30,000 D3 seems very high unless you showed a deficiency in Vit D? Were you deficient or just decided to go to 30,000?

[@allwynjagdale3392]

@@thomaslevine405 ko

[@barrodarwin]

how about the coumadin? do you still take it with vitk2d3?

[@verreal]

@@thomaslevine405 This is half the toxicity level but still way over what anyone would need, as far as I've heard/read, like 10 times a generous amount of D. Also it's weird that this person's channel name is k2d3, don't you think?

[@thomaslevine405]

@@verreal I have not heard of anyone needing that much vit. D unless they are low or have another specific reason for it? I take 2,000 units a day, but I really need to get a blood test. I also live in the tropics but not much sun for the past 2 months. K 2 mk 7 I take 200/day and nobody really seems to know how much to recommend.

[@nasarimeemusor3039]

this channel is one of the most underrated channel I've ever found on KZbin. How can there be only 7k subscribers!?

[@SELFPrinciple]

That’s so nice of you. Thank you for your support! The channel is growing thanks to folks like you!

[@sherimillman53]

I really love this clever vitamin K. Thank so much for a clear concise explanation and the safety. 🙏 You are improving people's lives

[@murarirajagopalan3771]

Great insight! Most Phosphates used as Fertilizers also have a lot of radioactivity which is often overlooked.

[@lucyflowerpot]

ive watcheed a bunch of videos on ckd and k2 and i was getting annoyed others just dont talk with the clarity that this guy does. I'm so relieved about finding this video. Thankyou very much, i will look into your other videos now.

[@kellidodson3943]

Thank you so very much for generously sharing your knowledge. You are excellent at explaining these concepts in laymen’s terms. Knowledge is power to those of us who are driven to maintain our health. I am so glad I found your videos!!!!!! Thank you!

[@SELFPrinciple]

Thanks so much for the kind words!

[@Sunset553]

Thank you. I wondered why my Dr had me start taking K2 last year. Now I know.

[@CaesarT973]

Vanakam 🦚 Thank you for sharing

[@madhavidasari8302]

Thanks for the clarity you have given doc

[@SELFPrinciple]

Thank you

[@christinevstork2379]

Thank you. Very informative 👏 👌

[@kencody8755]

great podcast, I've been taking k2 for over a year,one tablet aday 200mg,my GFR has increased from 20 to 28,there needs to be more research into this vitamin, my doctor had no knowledge of vitamin k2, I told him to google it.!!!.

[@mariefricchione437]

I started taking both FARXIGA and KERENDIA because my eGFR was 29! Now after 6 months my numbers have increased to 62! I take D3 with Mk2 mk7 as well. But doctor said it colts blood so stop it. I have stopped it but now I’m going back on it. I believe it helped improve my numbers. JMO

[@georgephilip9927]

Very good information. Thank u very much dr.

[@wilfredmiranda6930]

V. nice lecture on K2.

[@muzaffartirmizey8207]

Excellent doctor.

[@SELFPrinciple]

Thank you!

[@mard7569]

Thank you Dr Sean! Very informative, I appreciate your summary. I was looking to this video! As I mentioned in previous videos my brother has stage 3CKD, plus heart disease runs in our family. Thanks again!

[@SELFPrinciple]

Glad it was helpful! Thank you for your support!

[@mikem2208]

Your diet runs in your family more than any disease.

[@Marc_de_Car]

Thanks

[@charminealcantara7]

Thank you :)

[@mrb5481]

Thanks for sharing

[@SELFPrinciple]

Thanks for your support!

[@willlantion6096]

Thank you for your listen. I learn a lot when I eat salad I eat blue cheese what have all different types of vitamin K? And also I take Tums to pull out phosphorus instead of taking the binders I learned this from a KZbinr called oo kidney

[@bmniac]

Great clarity and brevity characteristic of Dr Hashmi Very useful. I have no serious health problem yet have been taking K2 with D3. but avoid calcium and have very little dairy(just buttermilk and a splash of milk in my coffee). I am 82.

[@SELFPrinciple]

Wow. Amazing job taking care of your health and being 82. True inspiration

[@bmniac]

@@SELFPrinciple Thanks Dr Hashmi

[@mwilliams-castillo9609]

Thanks for sharing very interesting information

[@caseyines5029]

hi and thank you. do you recommend any specific brand of the vitamin or dose to start with?

[@charlescallea1759]

Very informative!

[@eatstara]

I have a ckd friend..doc can you discuss this supplement calcium with magnessium for ckd.. Thank you

[@bornagainchristian2501]

is k2M7 vitamins good for CKD patients? Please advise.

[@rebekkad.2092]

thx

[@SELFPrinciple]

You are welcome

[@luckssj]

Have you looked at Glycocalyx Structure for it sit on top of the Endothelial cells and then you can help remove most chronic diseases

[@sushiedebipershad691]

Hi dr I have right artried calsificated block can I take k2 vitmains I am a vegtrain diet .

[@matoowen7076]

i am a stage 5 kidney patianti use mk-7 daily with d-3 i also use IP-6 as i heard it helps eliminate calseum in the blood and i take magneseum citrate what do you think about chanca piedra for calseum elimanation?

[@charlessavoie2367]

Add COQ10/ubiquinol

[@debnickel1098]

With vitamin K being fat soluble, if a person eats greens and other foods high in vitamin K1, would vitamin K2 put them way over on their daily amount of vitamin K? Thank you for the explanation on how important vitamin K2 can be.

[@SELFPrinciple]

K1 is different from K2. Daily intakes of Vitamin K are ONLY based on K1 and not K2. K2 does not have any established dosing amounts just yet.

[@Wrdwrk]

Brilliant…as always ! Particularly great when you help us renal folks. I have become lost in the shuffle with covid so have not heard from my doc in months. Think I should try this with the D3 and B12 hoping it might help. Thank you so very much for your excellent teaching ! 🇨🇦🇨🇦🇨🇦

[@SELFPrinciple]

Glad to help! Stay safe!

[@malli69]

What is a good brand?

[@ilsewenzel9424]

I've been on Warfaring for a number oy years. Dr's keep saying to me I need to balance the Vitamin K so that my INR doesn't go sky high. Your input please

[@mohammadalbahri4633]

What about taking Niacin for decreasing the absorption of phosphorus in the gut?

[@SELFPrinciple]

Unfortunately, niacin is not well tolerated in a lot of our patients. But niacin does reduce phos absorption

[@erminobenitez3122]

I been lately getting out breath and itching skin I used cream for the itching went I get out breath I just take my time and goes and come

[@coreysmith1481]

Is Vitanim c good for ckd Please Respond Thank you

[@donaatvernieuwe5746]

Hello doctor, thanks for this interesting topic. Some sources say that k2mk7 is blood thinning. Is that so? I take k2 together with nattokinase. Could that thins my blood too much?

[@bobcocampo]

How do you measure Vitamin k2 level in our body?

[@PaulYoungMinnesota]

I ate a lot of Natto because of fear of blood clotting from Covid and ate SO much I experienced vertigo from low blood pressure

[@edimoelvis9904]

You mean k2 can cause low blood pressure?

[@bornagainchristian2501]

My cratinine level is high (187) that is why my nephrology doctor told me my CKD is in stage 4. I also have OSTEOPOROSIS since 2016 however my endocrinologist did not prescribed K2 vitamins to increase my bone mass density Since K2 is good for my OSTEOPOROSIS, my question is is K@ vitamins also good for my CKD? Please advise. Thank you I am n Asian patient.

[@wassiwaseem5365]

So it mean cardic patient that taking asprine and clopidogrel can’t take the vit k2 mk 7 ?

[@cliveworth]

I am a 73 year old retired coal miner and I have started to take Vitamin K2 MK7

[@SELFPrinciple]

That’s great.

[@judithmargret5972]

I think k2 is not working for me anymore. I will have to listen to this a few more times to understand it properly. Thank you.

[@madhavidasari8302]

What do I need in my body to use the mk7 I supplement with ? Any prerequisites like day D3 ( which form of D3 ). Is taking Rocaltrol 0.25 preferable to Uprise D3 ? As per doc prescription ofcourse.

[@njsongwriter]

You can benefit from K2 without taking vitamin D.

[@barbnbirds]

Iam on Eliquis and have Afib.I was told i could take K2 or Mk2 7 , which i take, and i have no healthy diet restrictions.I do have to watch my sodium and i take Metropolol for BP

[@allanabbott8220]

Transcript 4:04 4:04 4:04

[@crazyfortreasure]

My mom has tried d3 and it gave her pain. I've not read anyone else dealing with that. She has stage 3 kidney disease and chf. Would love her to try just k2 to see if it can help reduce the calcium in her arteries. Is it ok to take just k2?

[@brandillysmom]

This is my mother, in a nutshell…. I have started to give her sublingual MK-7 K2. She has ESRD, Atherosclerosis, Afib, Heart Failure, Early Stage Cirrhosis of the liver and digestive disturbances. I giver her other supplements that her nephrologist and other doctor approved of. It’s my last ditch effort to improve the quality of her life. I wish I could have begun this journey with her 30 years ago, at the first sign of her troubles.

[@SELFPrinciple]

Thank you for being proactive in your mom’s health. You have a great heart.

[@mem1701movies]

@@SELFPrinciple does store bought canned sauerkraut have K2?

[@PlavoOka1]

Fermented sauerkraut has k2 plus vitamin c.

[@lindadurand247]

​@@mem1701movies Very little, you're better off making your own

[@AileenCares]

can you post also a home remedy to take in lowering blood sugar than taking metformin

[@njsongwriter]

Yes. It's called the ketogenic diet or the carnivore diet m

[@paulawagstaff686]

Look up berberine

[@lindadurand247]

Eliminate processed foods, carbs, starch and sugar

[@habibulalam7284]

I am 72 yr old asian male. Had my CABG in 1995 and a stent on the Left artery in 2014. I am hypertensive and diabetic. Both well controlled. I have CKD. Will vegetarian food help? Rgds.

[@bmniac]

A plant based diet wit much reduced grains esp wheat will certainly help. This is based on xperience

[@watchmanonthewall6962]

Ckd stage 3, 72 yrs old, Dr wants ma to start losartan. Is there any danger taking k2? Thank you

[@johnnewport8532]

Happy to have found your video -very informative. You mentioned not supplementing with K2 if you are taking Warfarin.Coumarin. Is this also true for Xarelto?

[@brandillysmom]

I’m not sure about that medication, but K2 doesn’t react with Eliquis. That is what my mother takes….

[@FitnessHealthAndBodybuilding]

Do warfarin patients have to settle for having Vitamin K2 deficiency?

[@koolbean2034]

Doctor, can you please share your thoughts and if there are any scientific studies about black cumin oil? Thank you

[@SELFPrinciple]

Sure thing. I’ll add it to the topics list

[@koolbean2034]

@@SELFPrinciple Thank you Doctor

[@njsongwriter]

Simply do a search for "Pubmed black seed oil"

[@ahlamkamil1091]

I do take K2 every day with my D3 but l am on blood thinners forever because of my serious Permanent AFib. I do take Apixaban and not Comadin

[@henrylee2964]

Dr Hashmi : I have tested positive for Hepitius B. My liver is ok so far. But are there any drugs and survival rate if i should develop liver disease? appreciate your comments

[@annawell2517]

Check out Milk thistle and Tudca for the liver!

[@chadwaldron3568]

So, I'm understanding that calcium is also a culprit and I need to lower my calcium intake?

[@abou8963]

K2 puts calcium in bones not arteries?

[@SELFPrinciple]

Yes, correct. K2 helps move calcium into the right places. Also, getting calcium from food is always advisable.

[@harryagrotis326]

Dr where are you located ?

[@njsongwriter]

I take K2 MK7 derived from natto. However, I will not eat a plant based diet. Not will I ever supplement with D3.

[@sagaabovecurseavisey9840]

So it advisable to take vitamin k2 specifically m7 when surfing for kidney

[@SELFPrinciple]

K2 is important for all including those with kidney disease.

[@banglazen2012]

Thank you so much for your clarification about K2 MK7. Atherosclerosis is also responsible for progressing CKD. So K2 MK7 is needed to prevent atherosclerosis. A CKD stage 4 patient has been taking Atobastatin 10 mg and Clopidogrel 75 mg daily to control her high Triglycerides level ( which is 604 mg/dL) and to treat thicken blood. The patient is also taking 100 mcg K2 MK7 daily alongside mentioned drugs. Please suggest a proper dose to prevent atherosclerosis and blood clot. Is it possible to contact you directly?

[@SELFPrinciple]

The difficult part is we don’t have the right dose for K2. Lots of new studies coming out. I’ll keep everyone posted as I see new research come out.

[@amymjennings]

@@SELFPrinciple I read that k2 is also useful to keep skin more elastic and youthful appearance in many patients in this with Doctors monitoring?

[@njsongwriter]

I take 300 to 400 mcg of K2 MK7 derivedvfrom natto daily. I also take nattokinase to dissolve soft plaque that is not calcified.

[@amymjennings]

@@SELFPrinciple hi Doctor, could you answer my questions I had? I asked for my husband's permissions to engage in conversation. Thank you

[@chaitanyadandavate8633]

Dr I am AS patient with c score of 375 . Off late I started MK7 200 mcg + D3 4000 IU and Magnesium 350 mg . No problem with kidneys or liver all reports normal . I want to reduce my Ca score . Is the dosage ok ?

[@njsongwriter]

My CAC is 305. I take 300 to 400mcg of K2 MK7 from natto plus 4000 IUs of nattokinase. I refuse to take D3. If I had a good reason to think I needed vitamin D then I would get a Sperti vitamin D lamp. I also take 400 to 500 mg of elemental magnesium a day. If you remove the calcium without removing the soft plaque under the calcium then you may be causing a bigger problem. This is why I take the nattokinase.

[@gurudeep7956]

Does k2(mk7) has affect on antiplatelet drugs(clopidogrel)?

[@SELFPrinciple]

No. it does not

[@barrodarwin]

@@SELFPrinciple how about aspirin?

[@njsongwriter]

@@barrodarwin Take nattokinase. Then you won't need aspirin.

[@rhondareese3908]

Is there a brand ok K2 with the mk7 that you would recommend taking.

[@SELFPrinciple]

Great question. I try to never give any specific brands. I shop at Costco and take the only brand they carry :)

[@PlavoOka1]

Dr. Berg has good quality supplements.

[@njsongwriter]

Just avoid the synthetic form. I use K2 derived from natto.

[@jp_snagbc8349]

Dr. Berg

[@chamanlallprakash6796]

Does k2 affect clotting

[@JodBronson]

I started K2 and within just a few days, I got a bloody nose and my blood was really thin. I can also smell my blood just by breathing. Because of that, I stop taking it.

[@SELFPrinciple]

Safety first. If you have a tendency to bleed easily, its very important to get it checked out by your doctor.

[@larryc1616]

What do you recommend in taking a vit K supplement? Mk7 alone? Mk7+Mk4? K1+Mk7+Mk4?

[@lindadurand247]

K2 MK7, with Vitamin D3 I take the liquid form of D3 6000 IU, 200 mcg K2 daily

[@agnescumlat3147]

can i take vitamin k2 and D3 while i am taking medicine for my blood pressure

[@lindadurand247]

Yes you can, I take it and am on BP meds, just space the meds and vitamins apart by 2-3 hrs

[@enugantiwarharish8320]

Can cure ckd k2 tablets

[@PositiveVibes360]

is k2 found in cucumin turmeric?

[@PlavoOka1]

I’m not sure but all fermented foods have vitamin k2.

[@LoveSumsItUp]

Plant based is high in toxic oxalates. … thoughts on how dumping oxalates is hard on kidneys

[@njsongwriter]

I have been dumping oxalates and recently started taking MSM because high oxalates cause low sulphur. Since doing that I wake up in the morning with pain in my left kidney. I'm thinking this may or may not be a good sign. Not sure yet. Maybe it just means that the oxalates are moving much like a kidney stone would. I'm also starting on Chanca Piedra to dissolve the oxalate crystals. Hydroxycitric acid is supposed to be good for that as well.

[@bobcocampo]

Please check if fermented fish and Fermented krills have vitamin k2

[@SELFPrinciple]

Remember K2 comes from bacteria. Hence fermented foods have it. I am not sure about fermented fish and haven’t come across any info in my readings. I’ll keep you posted should I come across on it.

[@bobcocampo]

@@SELFPrinciple Thanks. Fermented fish is almost part of our staple food in the Philippines.

[@EnglishandZor]

@@bobcocampo Is it not high in sodium po? If it is, it is not good to our kidneys.

[@bobcocampo]

@@SELFPrinciple Any test to check level of Vitamin K2?

[@CraigMullins1]

If our phosperous levels are still good in our blood is k2 as important? Is there a way to know how much we need to take and a test to know if we are taking too much? The pills I have are 100 mcg each. Is there a reason why a person would have dozens and dozens of calcium Pelvic Phleboliths? What about calcium deposits in the lung, assuming it’s not cancer. Don’t know yet.

[@SELFPrinciple]

1. Yes. Lots of other functions of K2. 2. there is no established dosing for k2 yet. The studies showed up to 360mcg was safe. 3. This one you want to work with your doctor on. As there are lots of causes why someone will have calcium phleboliths

[@CraigMullins1]

@@SELFPrinciple thanx!

[@lindseyjohn4789]

Would vitaman K2 be found in Kabuscha?

[@DesignCutters]

I have to disagree with your advice to not take K2mk7 if also taking warfarin/coumadin. As long as you get routine blood checks to measure your INR and adjust as necessary, it's fine. And the side effects of warfarin/coumadin - I have read that it interferes with calcium and how calcium gets used or dispersed in your body.

[@laurafloyd5177]

👍

[@SELFPrinciple]

Thank you!

[@preciousissah7395]

Can ckd patient take k2 with vitamin d?

[@lindadurand247]

Yes, with vitamin D3

[@chrishowe8614]

Please forgive me, I'm not an expert. But, there seems to be recent research that shows MK4 is the preferred version of K2. It stays in the blood for a shorter time because that is the form the body absorbs best. It was also shown that K1 and MK7 both convert into MK4 meaning that that is probably what the body wants and needs most. But you should check it yourself. I am just an info consumer here!

[@joeplacetas1]

Hi,,I'm 5 8" tall,, weight 100 kilos, 60 years old,,for the last 9 months I seen bubbles in my urine, on and off,,they desapear quickly, I had two tests done, one,,kidneys functioning tests, which was good,,no protein,,,the other tests showed my cretaine clearance was 40.35, a little low,,I was told that the bubbles in my pee could be muscle lost,,or a some liver fat,,,I know I'm overweight and I'm very cendentary,,,I was a little low in Vitamine D,,,so,,the bubbles in my pee are a mistery,,even though I was low in Vitamine D, I don't understand because I was taking Vitamine D,,,than I stopped because many articles in Google said D3-K2 was no good for the kidneys,,please advise

[@3Mores]

I am confused about what you've said. Is the upper tested limit for vitamin k2 360 milligrams or 360 micrograms? In this video at 7:21 you say 360 mcg, but in a more recent video, you claim that they have tested as high as 360 mg with no side effects. Since that is a 1,000 fold difference, I would like some clarification.

[@njsongwriter]

It's micrograms not milligrams. Big difference. 1000 mcg = 1 mg

[@charlessavoie2367]

People on dialysis need carnitine for cardiac protection.

[@vjayvjay7539]

Dear frnds how to take vit d3 supplements in doses Vit d level 30|mg How to raise

[@lindadurand247]

I personally take 6000 IU D3 and 200 mcg K2- MK7 daily

[@vjayvjay7539]

@@lindadurand247 thank you 🤝

[@jennifergreene2948]

I have CKD stage 3b I have Life Extension Super K soft gel supplements. I tablet contains Vit C 10mg Vit K activity 2600 mcg Vit K1 (as phytonadione) 1500 mcg Vit K2 (as menaquione-4) 1000 mcg Vit K2 (as trans menaquione-7) 100mcg Are these ok or should I get the Vit in the form K2 only?

[@SELFPrinciple]

Not sure why they have MK4 as it has poor bioavailability. This may be a bit overkill

[@bobcocampo]

Hope there will be RCT on mega dose Vitamin K2 up to 45mg

[@maverickmartinez]

Hi sean. Taking turmeric capsules as supplement. Is it good or bad for ckd3 patients? Thanks for reading my message

[@SELFPrinciple]

Curcumin (active component of turmeric) has lots of important functions. In general, powder better than capsule. It’s great for overall health in pts with or without cod

[@maverickmartinez]

@@SELFPrinciple thank you so much

[@njsongwriter]

Turmeric is high in oxalates. Oxalates are rough on the kidneys.

[@larryc1616]

​@@njsongwritertake the curcumin extract from tumeric so no oxalates

[@thomashall2753]

Which foods are best to boost K2?

[@SELFPrinciple]

Natto, sauerkraut

[@njsongwriter]

Grass fed butter and grass fed beef.

[@paulcalvert6062]

Thank you, but most of us are not Doctors and all of these videos are as if you are speaking to one. All I want to know is yes or no and how much to take if yes.

[@atrynaatryna5254]

Like 999❤

[@SELFPrinciple]

🙏🙏🙏

[@christinerodeheaver3516]

Help took to much D3 K2 toxic

[@hans-peterkausche5543]

: eat more Sauerkraut

[@user-px2sn8pr5t]

not concise

[@janedoe09]

BS

[@user-swingtrader]

You need to learn how to talk to laymen. Everyday people cannot understand your "tech" language.

[@supremoluminary]

Why do you double is? “The reason is is” -?

[@charminealcantara7]

Thank you :)