Why Haven't We Cured Cancer?

[@LeoWattenberg]

Please never again say "a few decades ago" when referring to 2005

[@MinuteEarth]

Sorry about that! One score and zero years ago, our fathers brought forth upon this...

[@Artaxo]

It's been barely a minute

[@50-50_Grind]

I recognize this reaction, I had it too [censored] ago. iT's jUsT a PhAse. No seriously, it's really just a phase. You'll be OK.

[@trashman966]

wait until next year, then call it a couple of decades ago.

[@mister_r447]

It's only 2 year after i was born. I'm 21.

[@YeTism]

Let’s take cancer and push it somewhere else

[@samueltorres4967]

That idea, may just be crazy enough, TO GET US ALL KILLED

[@amiralipurlotfi-f5y]

We all will do die by it

[@AutismoGamer]

@@amiralipurlotfi-f5y Your assumptions mean nothing

[@Struhsie]

Wait! I think he’s onto something…

[@babilon6097]

Hope it works.

[@KyleBaran90]

Whether it works or not is irrelevant. You're worth more to the medical industry alive than if you were cured or dead.

[@Chefofzejungle]

same

[@isabelleblake8732]

this makes so much sense though?? obviously we can’t throw every drug at a patient to see if they’ll work, but if we isolate the cancer cells externally, we can throw every drug at them at the same time and have a better idea of effectiveness than we would have in YEARS of treatment trials in the patient. why didn’t we do this before?? is this particularly expensive?

[@eragon78]

It probably is very expensive. You need to isolate the cancer, then culture it a bunch, then test dozens to hundreds of different drugs on it, many of which may be very expensive, just to even SEE what works. And then only IF one works, can you actually begin treatments. So you end up paying for potentially hundreds of drugs before even beginning treatment and there isnt even a guarantee youll find one that works. That makes this method very expensive, which makes doing it en mass pretty difficult. However, there may be some ways to mitigate the cost. For one, you can try testing only the cheapest cancer drugs first, since if one of those does work, it can save a lot of money over testing the more expensive drugs. And then just work your way up to the more expensive drugs as needed. So between that, and working heavily on reducing the cost of cancer treatments across the board, that could potentially make this more affodable. But I dont see a situation where a method like this is ever cheap. Its always going to be expensive. But it may be possible to get it cheap enough that, with a good universal healthcare system, we could use it on a lot more people and vastly reduce the deadliness of cancer.

[@hadisoufi7752]

it's expensive, and also it's hard to cultivate cancer- even if you can do it, it takes time to grow the samples to the point where medications can be effectively tested, time which you may not have. it's not until recently that there were even enough cancer treatment options that this approach was worthwhile. the main problem with this approach though is the same with all functional medicine- they don't teach you about the disease. if you treat person A's cancer using a functional approach, you've learned nothing about cancer that you can then apply to improve person B's treatment, you've just brute-forced a solution. a proponent of functional medicine would then say, with good book-keeping, a mass functional approach can provide massive amounts of data, way more than a standard study would, but of course this comes with it's own caveats, and so on and so forth. it's a complicated conversation. nobody would argue that functional medicine isn't extremely important, anything you do to save a patient's life is good, but when combined with the other problems I mentioned earlier, explains why there wasn't wider-spread research into this subject until certain problems were solved.

[@Blueeyesthewarrior]

@@hadisoufi7752 Thank you for taking the time to explain this. I was genuinely surprised we hadn’t been doing this with cancer, considering the fact that we culture bacterial infections to test antibiotics against them. But it’s probably far easier and less expensive to culture bacteria than cancer cells.

[@TherealNiqqa]

Why don't we just give cancer cancer?

[@moamal9267]

Genius

[@stm7810]

That's how we get I am Legend.

[@derisory]

But what if the cancer cancer gets cancer? Then how will we treat the cancer cancer cancer?

[@tajuddinahmed3379]

OH MY GOD YOU ARE A GENIUS

[@loganblakely3448]

With cancer cancer cancer cancer

[@kevin-y]

Hopefully those individual results are being recorded and analyzed for patterns that will make the treatment cheaper and more accessible in the future!

[@GiantsRTheBest1]

What did not expect my Alma Mater just randomly popping up as leading the charge against cancer. Let’s go Panthers!

[@Blueeyesthewarrior]

Same! Made me proud to be an alum.

[@Lambdadelta-kyo]

Cancer is not one disease, it is a hundred thousand different diseases, all of them ultimately caused by exposure to the ravages of time. I don't think we will truly be rid of cancer until we are rid of senescence.

[@jakistam1000]

I mean, an infection is not one disease, but hundred thousand different diseases. This means that there is no one cure for all infections, but doesn't have to mean we need 100000 different cures.

[@randuRBLX]

THIS i keep having this thought that even if a person is said to be cured permanently eventually a protein will misfold again and with chance may start cancer in said person once again this comment strengthens it

[@Samu2010lolcats]

@@randuRBLX You're confusing cancer with prions.

[@kainpmn1401]

Thanks to the MinuteEarth team for creating these videos that teach us something new.

[@animalbliss3713]

Praying for the success 🙏

Great video as always!

[@hanchen267]

To defeat your enemy, you must first become your enemy

[@vamshidaren9649]

Happy Halloween!

[@平和-v1z]

Science is amazing!

[@crimsonraen]

This is so cool! :)

[@HelPfeffer]

cells: Ctrl+C Ctrl+V docs: *gasps* [research] docs: Ctrl+C Ctrl+V

[@Ryukachoo]

I wonder, does this also preclude making mRNA vaccines which target those particular mutations as well? If the entire immune system is targeting that mutation, maybe it'll work better than some specific treatment. Also wouldn't this copy and paste approach be incredibly expensive because you're growing tons of cell samples per-person? Edit; hold on LESS THAN A WEEK turnaround? That's more impressive than the approach itself.

[@NYKevin100]

A major problem with cancer is that the most dangerous/serious cancers are really good at telling the immune system to leave them alone. That might sound like a dumb problem, but you have to remember that every cell has a full copy of your entire genome, so all of the information about your chemical signalling pathways are in there. If a cancer cell mutates in just the right way, it will start expressing signals that the immune system interprets as an off switch. (If it does not happen to mutate in exactly that way, then there's a good chance the immune system kills it before you even know you had cancer.)

[@mrcat6433]

At this point I excitedly wait for the puns everytime I watch one of your videos

[@kainpmn1401]

PS: i kindly request everyone to laugh at the puns minuteearth creates.

[@MinuteEarth]

Groans are welcome too!

[@Rkcuddles]

Tell us how protein folding is going to help!

[@GeoffryGifari]

Copying cancer sample from one patient and varying treatment over the copies doesn't sound very scalable... can a method be derived from this that efficiently treats many cancer patients at a given point in time?

[@MinuteEarth]

It's getting there! Labs are now able to turn around patient results in less than a week.

[@user-ix2yh6gx4e]

The thing with cancer is that it is associated with ageing itself. We basically get cancer cause we are able live longer, so i think it will always be a thorn on our back 😢

[@andrewcavallo1877]

From a numbers standpoint, definitely. The longer you are alive, the greater chance for one of your cells to mutate. However there have been relatively recent experiments with mice that demonstrate the ability to alter a deteriorating epigenome to reset aging, it’s pretty cool stuff. Of course after they are reset they age like normal again but if the experiment is replicable upon the same mice then it could be groundbreaking

[@ashvio]

Actually, cancer rates go down significantly for people who live into their 90s or longer, which implies there are genetic or environmental factors that can prevent people from getting cancer.

[@halloweendad]

I heard someone say once that there almost as many types of cancer as there are cases.

[@Random_girl.211]

I wish cancer didn’t exist it just makes life so much harder ❤❤❤

[@acediadekay3793]

This means that whenever a cancer survives all of the drugs... We will have Super Cancer (like Butcher from The Boys)

[@Ellliptic]

answer to title: I hope so

[@Phymacss]

Original title: can we cure cancer by copying it?

[@Moorb0y52]

2005 was 10 years ago in my brain, please don't shatter the illusion

[@lukasp.5243]

This is where money should go. Instead it goes to celebrities and army.

[@moamal9267]

We are slowly getting closer to the cure...

[@zpydd_]

damn, i wish it was easier

[@Zahri8Alang]

Dont tell me it has something to do with government banning medical abortions too

[@vagabondcaleb8915]

Not unless we can copyright the copies. Why fund the research if we can't protect our profits?

[@mattmaloney5988]

So the new idea is to culture the cells and try treatments on the cultures?

[@LouisC777]

Because it’s more profitable to treat it than curing it

[@affe8808]

I forgot

[@bivcbmtgstgtssscqcrddgtrsm2257]

Well, at least it's something...

[@Berry_is_fine]

“20 years ago, thanks to a giant breakthrough. We thought we were about to cure cancer” But the people involved mysteriously disappeared

[@Struhsie]

When looking at the title, my reaction was: “and why haven’t we cured the common cold?” Then I realized, curing the common cold would be even easier than curing cancer :/

[@Helonagvv1]

Helo

[@realdragon]

Why haven't we cured stupidity?

[@westonding8953]

Are there other ways that cancer is caused other than DNA mutations which trigger the chain of events causing the cell clump to grow out of control?

[@ThisWorldMakesMeSad]

Screw Cancer

[@Domogamer-h6s]

Everything evolves into crabs

[@conspiracytherapist1869]

Treatment is a BIG business 😉

[@outrage_swampert979]

Maybe you shouldn't name the researchers out loud like that. They might soon disappear without a reason...

[@NexusGamingRadical]

Unfortunately I was born in July, so there's no cure for me.

[@suplementosive2059]

Buen video, entonces soluciones informáticas de pelea de virus de computadora no tardaran en adaptarlas a enfermedades biológicas y tipos de cáncer de modo que la medicina avance para alcanzar los niveles médicos de startreck, si retoman las ideas del viaje en el tiempo en startreck no me extrañaría ver soluciones nuevas por estos tiempos en la tierra como en su tiempo fue con la película de las ballenas en startreck, ahora con otra temática y decirles edad media moderna a estos tiempos, sugerencia.

[@suplementosive2059]

Por cierto entonces los científicos e ingenieros crearan nuevos tipos de sangre para estudiar mejor los tipos de cáncer y como encontrar la debilidad específica del cáncer, desde estudiar cáncer de animales del abismo oceánico mejor que resident evil revelations hasta cáncer en animales zootecnia creados en laboratorios para esos propósitos de modo que tengan conejos, liebres, roedores, simios y primates para estudiar el cáncer con esta técnica de copiar cáncer con tipos de sangre de oro de cada especie biológica mamíferos, sugerencia.

[@MinuteEarth]

Gracias! Necesitamos doctor "Bones", no?

[@nooks12]

No. Metabolic theory of cancer. All cancer cells cannot use ketones for fuel.

[@pyeitme508]

Finally

[@FacterinoCommenterino]

Today's Fact: The highest number of concurrent players in Minecraft was over 91 million, recorded in March 2021.

[@KyleBaran90]

Id ask why, but thats during lockdown

[@richardrahl1919]

we all know why.💀💀💀

[@jamesh7123]

The answer is simple. The share prices of big pharma would plummet. Fact.

[@Marionette_Doll]

In this case, share prices would skyrocket. Cancer treatments are one of the most expensive treatments out there. An actual cure for cancer would be vastly cheaper than the treatments we have now, so insurance companies wouldn't lose out on nearly as much from it, while pharmaceutical companies could charge almost anything they wanted because insurers would pay to avoid the costs of cancer to themselves.

[@bensoncheung2801]

🔥🔥🔥

[@CT-pi2gl]

Give cancer cancer

[@sethrod13]

I figured big medicine didn't allow for cures to go widespread due to losing patients

[@Slimothy]

Keto/Carnivore + Sugar reduction to 0?

[@zlodevil426]

Because chemotherapy is more profitable than a cure

[@emilstvring7577]

Actually not, cancer is actually the odd one out, compared to something like diabetes, where insulin production and selling is more or less the only thing we can do about it (or at least want to put funding towards), cancer curing is one of, if not the single most popular and well funded field of science, there being thousands of companies researching and developing non-chemo ways to deal with cancer as to why, my guess is that someone with diabetes who gets insulin is still in the work force, so you won't "gain" anything from curing them as a capitalistic economy (as happiness sadly isn't worth many dollars), but someone with cancer probally don't work, and it's hard to squese money out of someone that doesn't have any income

[@trueblade3636]

Because big food and big pharna does not want this.

[@tombkings6279]

Skill issue

[@yausof4150]

lol i kinda remember a clip andrew tate talking about this method of treating cancer in one of his clips

[@AutismoGamer]

Q: Why haven't we cured cancer? A: The notion that a cure for cancer has not been found due to financial incentives is a misconception. In reality, cancer is an umbrella term for over 200 distinct diseases, each with its own genetic mutations and complexities. This diversity makes it unlikely to find a single cure for all cancers. Moreover, cancer cells can develop resistance to treatments, adding to the challenge. The pursuit of a cure is ongoing, with researchers worldwide dedicated to finding effective treatments for the many forms of this disease. 🤔🤔 I guess the billionaires control every lie that we're told. They don't cure patients if the same clinics and hospitals are sponsored by corporations that make the poisons we eat.

[@freezingsunset7354]

all cancer treatments nowadays are combination treatments to most extent: surgery, radiation and systematic therapy. the order may vary nice job pushing big pharma agenda by only talking about drug based solutions local therapies are still the most effective, cheapest and safest treatment options: surgery and radiotherapy

[@Ghost-pb4ts]

Quantum computing should make this process super easy in theory It still baffles me how everyone has cancer cells in their body but most time immune system takes care of it But we don't know why that process sometimes fails.

[@lunkel8108]

I would say we actually know quite a bit about processes by which tumor cells can evade the immune system. They can express immune checkpoint proteins, produce cytokines that downregulate CD8 T-cells and NK-cells while upregulating regulatory T-cells and certain macrophage subpopulations, lose immunogenic passenger mutations, downregulate/lose parts of MHC-based antigen presentation, create physical barriers against immune cells, etc. All of this while also promoting inflammation in ways that help the cancer develop and spread. There is still a huge amount we have left to learn, but we do have a grasp on the basics, I'd say. All of this can happen because cancers undergo rapid evolution under the selection pressure of the immune system, a process called cancer immunoediting.

[@Ghost-pb4ts]

@@lunkel8108 yeah and then you put those cancer cell in someone else body not human body to be specific And the immune system will eat those cancer cell for breakfast

[@Ghost-pb4ts]

@@lunkel8108 wrtitng this comment again cause youtube got offended even though those cells have learned to escape the immune system If u put those in some other mamall body maybe human too their immune system will anhillate those cells

[@AutismoGamer]

Q. Why Haven't We Cured Cancer? A. Because if you cure every patient then you wouldn't have more money to make off the dead' and their living relatives. They get us hooked on Synthetics for a reason. They refuse to acknowledge Organics as medicines so they mark them as "Drugs" so there's taboo and a stigma around the study of these plants if you aren't backed by a rich org/corp or GOV. It's a game and we're forced to play along

[@SuddenSwine]

To make money?

[@ChickiPiqiArt]

Can u pin me? 😅😊