Bleeding Disorders (ITP vs TTP vs HUS vs DIC) || USMLE

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[@SJ-hd1br]

It would be amazingly helpful for those of us prepping for step 2 to have this video include treatment. :) From the Third Edition of Step up to Medicine ITP treatment: steroids/IVIG, THEN splenectomy, THEN romiplostim/eltrombopag. For TTP: Plasmapheresis, case by case basis for steroids and splenectomy, but transfusion is contraindicated. For HUS, the only thing I remember from Q banks was an emphasis to NOT give antibiotics in a patient with bloody diarrhea because it could actually trigger HUS. Medscape says that care is supportive.

[@rajatsingh24k]

This is what I was looking for. Thanks!

[@farahwaseem8894]

THANK YOUUU

[@karataych0p]

we don't need that when we have you

[@sadimohammadarad1784]

Great 💯

[@pinkrox154]

Thank you!!!

[@ast1848]

Glad you guys are back, hope to see a regular flow of vids!

[@Queenin06]

You explained my 6 hour lecture in 7 minutes! THANK YOU!

[@cos244]

You're an absolute life saver man!! :D Love the The Terrible Pentad mnemonic - I'm gonna use FAP RN for the pentad memorisation xD

[@info.planet4337]

TTP = PARTNERS P: low plt A:anemia R:renal T: temperature rise N: neurological defect ER: emergency, admission S : schistocytes

[@fadihamati10]

The Terrible Partners?

[@nightelf4]

DIC D- Decreased fibrinogen with D-Dimer increased I- Intravascular hemolysis - MAHA and schistocytes C-coagulopathy (or can't stop bleeding) with increased PTT/PT/INR

[@lotyloty2]

What does maha mean?

[@roshlend1370]

Microangiopathic hemolytic anemia

[@MHSMagicLuver]

I just want to say thank you. Im in PA school and I have watched this multiple times. I keep coming back to this video when I need a refresher.

[@cementra2007]

I'm so glad I found this channel.

[@elyandrade5656]

this channel is my favorite. glad to see ya'll back :)

[@user-sw6hl1dd2x]

I can't prescribe the beauty of this lecture..simple, informative and we'll organized.. Thank u so much.

[@alejandrabeltran297]

You literally saved my life. Thank you so much.

[@andreafarrar2350]

Thank you SO VERY MUCH for clearing this up for me. Just reading a book doesn't help me very much. You rock!

[@TK24958]

low key obsessed with your channel. posting this in my academic group

[@michaelangelo9240]

Thank you. Very well explained. Makes perfect sense.

[@makeitaleapyear6062]

good to see you guys back !✌

[@smartaleck05]

God bless you! So glad you posted this sooner- my step exam is in

[@madamhenry]

Did you pass????

[@smartaleck05]

Sorry, I did! + forgot about this post so I donated lol. Now I'm about to take Step 2 CK :D

[@judysams3457]

Õ

[@ANabiha]

just curious about how you’re doing now :o

[@attiea85]

@@ANabiha Me too :)

[@Be1smaht]

I love that you just got into it. No intro just go

[@christian9alexander]

Brilliant video - this was a 2 hour lecture for me in school! But I also love how at 2:46 your washing machine ended and you can hear it in the background haha!

[@comedy0stuff]

Please Please more Cardiology and Respiratory related Dirty USMLE Material Thanks so much for all your content

[@lisagonzalez2902]

I appreciate this video! Extremely helpful. Thank you so much, once more.

[@HafizahHoshni]

Simply excellent. Very grateful for clear, concise and well presented video. Thank you for the great channel. 4/9/2018 😊

[@Sweetnsilly18]

Thank you so so much this! I hope you get infinite happiness in life 😭🥰

[@johnklens8812]

Wow this cleared everything up!! Thank you!!

[@dramina2326]

Great as always.Thank so much🙏🙏🙏

[@JC-je3jc]

Increased bleeding time doesn't necessarily mean platelet destruction, but could also be a failure of aggregation or adhesion with normal platelet count

[@ericnorthmen4118]

Please make playlist for patho. Your videos are superb

[@Kashif259]

Thank you so much! This is super helpful!

[@BerniesLife]

this was so helpful! thank you

[@alycks6056]

awesome, well explained

[@johndube4536]

very helpful... thank u so much Sir

[@VampireDiariesBiebs]

You’re the best!!!!!!!! Thank you

[@andreayb0523]

Great video! Thank you :)

[@imgingi]

I was WAITING for FAT RNS for TTP!!!!!! ( Fever, Anemia, Thrombocytopenia, Renal, Neurologic)

[@DirtyMedicine]

we don't waste our time with shitty FA mnemonics that make no sense

[@lisagonzalez2902]

Yeah. There's a lot of mnemonics in FA that is pure nonsense, random letters.

[@roshanbagga1401]

hahaha i love it

[@SaiRam-nz9sy]

@@DirtyMedicine once a rebel, always a rebel.

[@colbycarnes5786]

Note: ITP is IgG antibodies against GpIIb/IIIa

[@raedalghamdi1790]

From Arabia Peninsula 1 million thanks

[@daphrosemukabaranga4946]

God bless you. Can you talk about TPK? Thanks.

[@imranafzal3973]

Thank U sir...Love from Pakistan

[@aayushbhadani8351]

This was so good!

[@tawafraaya3910]

best explanation everrr

[@salmael-khateeb9989]

very helpful thanks a million !

[@LuanO7]

Great video!

[@roshanbagga1401]

thank you my guy

[@roshanaksharifi1181]

Thank you so much.

[@dineomakgobatlou2434]

Really helpful...thanx

[@DOC_951]

can you make a video for the vision defects? (bitemporal hemianopia, macular sparing, etc)

[@drsultansaudagar2733]

Mr. 2006 for this you can watch video of armando hasudungan.you will understand it.

[@tanyaradzwagahadzikwa9545]

this is a good explanation

[@karimoon270499]

I cracked up at whadufuq and DAMN IM CLOTTING

[@mariesa7338]

Amaaaazzzinggg

[@liebedich2441]

Thanks but the chart comparing the differences is not so clear in video,where can i get the pics of the chart please?

[@Peace597]

Thank you!

[@ahmadharb13]

May I ask what is the cause of fever in patients with TTP?

[@ghassanaswad4034]

well done , thnks alot

[@alexabentley1617]

LOVED THIS VIDEO OMG

[@leeromeo8635]

Dam man you are a god!

[@alijilani1214]

I thought ADAMSTS13 cleaved vWF multimers into monomers and those multimers are the ones that activate the platelets

[@amandahlaba8875]

me too

[@salmael-khateeb9989]

SAME

[@Dranamolous]

The end result is the same So his description is good for the sake of simplicity. I’ve never seen a question that hinged on that detail

[@bashayeralrefei2963]

Sir, how can i thank you? You are a life saver. Looooooooove you, your channel and your amaaaaaazing mnemonics

[@quadtos857]

@Bashayer Alrefei, you can thank him by donating on Patreon every month from $1/month to .......

[@bashayeralrefei2963]

@@quadtos857 hahaha ok

[@leezhengyangbrandon5080]

Bro, it's schistocytes btw, not schistiocytes. I love the video, thank you

[@DirtyMedicine]

Tomato, tomahto

[@joshmcgoo]

From first aid: TTP = FAT RN Fever Anemia Thrombocytopenia Renal Sx Neuro Sx

[@zhwart.hassan2199]

THANKS KEEP GOING

[@eakkaya204]

just..... I LOVE YOU

[@sreejithmg9101]

thank you...

[@srirambhardwaj2343]

Thank.you.very.much.

[@AJohnson0325]

Aren't you not supposed to give platelets to TTP? I think the treatment is steroids and plasma exchange.

[@waqasashraf6552]

How do we differentiate HUS and TTP since both will have everything in common (including creatinine elevation) Is it just by the hx of diarrhea or am i missing something ?

[@andrewholst5067]

Yes, recent illness in the vignette most likely

[@michaelmakarchuk8662]

TTP - pentad = My Kid Throw Fits Microangiopathic haemolytic anaemia (My) Acute Kidney injury (Kid) Thrombocytopenia (Throws) Fever & Fits/seizure (Fits)

[@wakylaugh]

Amazing

[@nimraaslam7715]

Thanks

[@soumitroy4549]

thanks

[@vikramadityajha8924]

Sir role of Vit b12 and folic acid in thromcytopinia.

[@nwabuezeozuzu6370]

Thank you for breaking this down 🥲

[@batoolqassim9715]

I can’t find your seronegative arithritis video 😭😭😭😭😭😭 did you remove it ?? Please bring it back 😢

[@Anonymous20186]

Thx alot

[@gokul8326]

Thank u

[@ResistmeJocy]

Damnn im clotting lol love your videos

[@muhammadjunaidali769]

awesome

[@thabephalane8961]

ITP isn't a immune thrombocyptopnic purpura

[@ahmedhussin1834]

Updates about the book ?

[@mahmoudkazim572]

Nice

[@leeromeo8635]

Dam you are too great I have to leave another comment OMG

[@loganmarshall7380]

Tooooooooo good

[@amyjojinkerson6745]

how do they get these medical terms

[@kamalghimire4148]

hemolysis in hus : toxin mediated hemolysis or due to thrombosis? written sth else n u told sth else.......

[@neehajoy4597]

Exactly same doubt here

[@mehrdadpilsham4211]

I accually had itp and it’s super serious the doctors thought I was gonna die😭

[@MSDawar2k17]

❤

[@JeanetteAAvila]

My daughter has TTP she can relapse she feels so dizzy😭😭😭😭

[@frostmageshark6277]

I had itp

[@riccikalaya4614]

Damn I’m Clotting

[@Be1smaht]

Idk about damn I’m clotting… because the DIC leads to decrease in clotting factors….

[@DirtyMedicine]

But yet you clot everywhere. Hence the mnemonic

[@silvermartin4160]

TTP: F'N RATS Fever Neuro symptoms Renal failure Anemia Thrombocytopenia Schistocytes

[@shirinaminoroaya3171]

coolllllll

[@Amritpalsingh-mc4kx]

The natural treatment of ITP is possible without causing any side effects. Planet Ayurveda from India offers ITP Care pack which are very effective and treat the condition of ITP naturally without any side effects

[@luna.kashyap1313]

I love u

[@Kidszone01238]

I m itp patient

[@daphrosemukabaranga4946]

Did you got help ?

[@jefflowery7338]

Same

[@optikalillusion777]

More like stomach bacteria...

[@DirtyMedicine]

the term was used in the common vernacular, calm down

[@optikalillusion777]

@@DirtyMedicine That bothered you? LOL.

[@HockeyGuy_in_STL]

spellcheck: Schistocytes, histiocytes

[@DirtyMedicine]

tomato, tomahto

[@LilFella67]

Sounds like you have a sinus infection but you just press on! Get well.

[@irisartin385]

You're misspelling and mispronouncing "schistocytes".

[@MILITO110]

1746366636366 words in a second am not American and many like me 😔🤬

[@gdhbgsgsuhfg9048]

Yang milih allah like 40000 ya