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DON'T Do This to Your FOODS!
Advanced Glycation End-products (AGEs) are harmful compounds that form when protein or fat combine with sugar in the bloodstream through a process called glycation. AGEs can also be ingested through foods that are processed under high temperatures, such as grilling, frying, or toasting. The accumulation of AGEs in the body plays a significant role in the aging process and is associated with the development of many chronic diseases.
Here’s how AGEs impact health across various conditions:
1. Diabetes
AGEs are particularly significant in the context of diabetes because high blood sugar levels accelerate their formation. In diabetes, the excessive production of AGEs contributes to vascular complications by promoting inflammation and oxidative stress. This damage is a key factor in the development of both microvascular complications (such as diabetic neuropathy, retinopathy, and nephropathy) and macrovascular complications (such as heart disease and stroke).
2. Cardiovascular Disease
AGEs contribute to cardiovascular disease by inducing the cross-linking of collagen in blood vessels, which results in stiffer vessel walls and impaired vascular responsiveness. AGEs also increase oxidative stress and inflammation, which can accelerate atherosclerosis-the buildup of fats, cholesterol, and other substances in and on the artery walls.
3. Kidney Disease
In the kidneys, AGEs can cause thickening of the glomerular basement membrane, leading to impaired filtration and eventually chronic kidney disease. They can also modify proteins in the kidneys, impairing their function and contributing to renal failure, a common complication in advanced diabetes.
4. Alzheimer’s Disease
Research suggests that AGEs may play a role in the development of Alzheimer’s disease and other dementias. AGEs accumulate in neuronal tissue and have been shown to promote the formation of amyloid-beta plaques, a hallmark of Alzheimer’s disease. They also impair neuronal function and promote inflammation and oxidative stress in the brain.
5. Skin Aging
AGEs have a direct impact on the aging of skin. They promote the loss of elasticity by affecting collagen and elastin, two proteins that keep skin firm and elastic. This leads to wrinkles, sagging, and other signs of aging skin.
6. Bone Health
AGEs affect bone health by altering the properties and function of bone collagen. This can lead to increased bone brittleness and a higher risk of fractures.
**Dietary Modifications: Limiting dietary intake of AGEs can help reduce their levels in the body. Foods high in AGEs often include animal-derived foods that are high in fat and protein, especially when cooked at high temperatures (e.g., grilling, frying). Incorporating more fruits, vegetables, whole grains, and cooking methods involving lower temperatures or more moisture (e.g., steaming, boiling) can be beneficial.
Use acidic marinades like lemon juice and vinegar to reduce AGEs
**Blood Glucose Control: Effective management of blood glucose levels is crucial for reducing the formation of AGEs. This can be achieved through medication, dietary changes, and regular physical activity.
**Antioxidants and Anti-inflammatory Agents: Dietary antioxidants (found in colorful fruits and vegetables) can combat oxidative stress associated with AGEs. Some supplements, such as alpha-lipoic acid and vitamins C, E, D, NAC, Benfothaime, B6(P5P) may also help reduce oxidative stress.
**Regular Monitoring and Management: Regular check-ups with healthcare providers to monitor and adjust treatment plans as necessary are critical for managing diabetes and its complications.
www.ncbi.nlm.n....
www.nature.com...
Dr. Jin Sung is a Chiropractic Physician who specializes in the management of complex chronic conditions in Massachusetts, 30 minutes north of Boston. He utilizes natural and alternative therapies to help manage complex cases such as Hashimoto's, autoimmune conditions, IBS, SIBO, chronic fatigue, brain fog, early Alzheimer's, etc.
www.DrJinSung.com
Office Contact
978 688-6999
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The content of this video is for educational purposes only and does not constitute medical advice. Please consult with your physician before embarking on any dietary changes or taking any nutritional supplements.