Gene Therapy for Human Ageing | Elizabeth Parrish

In this week's webinar, Elizabeth Parrish, CEO of BioViva USA gave an outline of what BioViva has achieved to extend the human health span. The approach combines state-of-the-art data collection with the development of novel interventional strategies.
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Disclaimer: The opinions and advice expressed in this webinar are those of the speakers and do not represent the views and opinions of the organizers and National University of Singapore or any of its subsidiaries or affiliates. The information provided in this webinar is for general information purposes only as part of a general discussion on public health. The information is not intended to be a substitute for professional medical advice, diagnoses or treatment; and cannot be relied on in place of consultation with your licensed healthcare provider.
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All of the proceedings of this webinar, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved to the speaker or NUS. No statement or presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript or other use of the material presented at this course without the permission of the speaker or NUS is prohibited to the full extent of common-law copyright in such material.

[@dmana3172]

I can't wait for first human trial to help me rewind my age. I'm almost 50. I hate getting old. I want to go back to 21 years old again and feel exactly 21 again and get the energy back 21 again. :)

[@leiladasha]

Med beds age reverse to 30

[@cyberreality7774]

Lol horrible hybris

[@audahka1]

Can't be more proud of you Liz! Keep rolling!

[@universe25.x]

I don’t want to get old 😭

[@cityplanconsultores2188]

Liz looks genial!!

[@johnstibal2131]

Utilizing AI learning for drug development has shown great promise in reducing drug development costs.

[@gringogringo218]

I think it really works!

[@user-sn5ih6fi6m]

I would do anything to look younger. I don't wanna live forever but I hate looking old. Most men like young women and I hate being 27. They say I have hit the wall. I can't even imagine what happens when I turn 30. Experiment on me, I would do anything and test any gene therapy if there is even a small chance of looking younger. If you need volunteers I am up.

[@Rcomt]

Are you, being 27, looking for a boyfriend among teenagers? Most normal men would never look for a teenager girlfriend except those who are pedo or teenagers themselves.

[@centenomartin]

You need to date other types of men and embrace aging

[@cyberreality7774]

85 years old escorts still have tons of clients

[@kaxa286alaverdashvili9]

This is genius. It is necessary to perfect this technology to the end and make it accessible to everyone.Many people suffer from the diseases of old age and this salvation would be for them.

[@Mask-pb3ly]

It is genius but costly. Also, the threat (or side effect) is still unknown. The information on the progress in this area has been suspended due to unknown reason. I can guess that someone who is very rich and who care about overpopulation of our planet paid to this company to keep a silence.

[@rhyothemisprinceps1617]

One of the gene therapies Ms Parrish undertook was for follistatin (which downregulates myostatin and increases muscle mass). Follistatin is expressed in the ovaries. I keep hoping that in one of her interviews she will discuss her health in more detail, including her reproductive health. It's personal information, of course, but it would help to know more.

[@chronokoks]

Oh god please no, we don't need old hags getting new wind and trying to find a new baby daddy. Jesus that would be awful for the society.

[@rhyothemisprinceps1617]

@@chronokoks Ms Parrish can look after herself, as can most older women. That's what bothers you.

[@chronokoks]

@@rhyothemisprinceps1617 I did not aim that comment at Liz at all.

[@rhyothemisprinceps1617]

@@chronokoks You very clearly meant that against all women. FOAD.

[@johnniejay]

@@chronokoks Thats the whole point of these therapies - no more 'old hags'. Way to showcase your ageism though.

[@stevenchen1345]

Bill Andrews has been vocal about not using leukocyte telomere length as a measurement of telomere attrition, so why did Liz say those were the tests done for her? Why not other kind of tests that more accurately assess telomere length? Or were those tests done alongside leukocyte length and had scores analyzed as well.

[@iansmith3292]

Bill Andrews was peripherally involved. It is "a study" but not a definitive study. They did the study that they could do.

[@jiujitsuproject]

When will these gene therapies be affordable for most people instead of the ultra wealthy?

[@earlaweese]

*Hopefully it’s distributed as much as the coronavirus vaccine.*

[@larapo8691]

I don't think that gene modification for the purpose of reducing biological age will happen in the foreseeable future, let's not fool ourselves. Most likely it would be used only to treat extreme medical conditions (children, blind, quadriplegics, etc.) when nothing else works, but I don't think it would ever be used to reverse natural aging process to extend life span in general population.

[@loboz631]

@@larapo8691 money talks, theyll have monthly pills or treatments that you can have a lifetime subscription. Whats better than a product that last forever, its better than the medicines they have now that keep you perpetually sick until you die.

[@janparker6724]

yeah sounds great but integrated health systems treatment starts at 75k plus travel.

[@claytontom7204]

$75,000 or DEATH.. your choice! If you have $75,000+ NO BRAINER

[@timothykaliszewski7459]

Yea but what if you don't have 75,000 +? Many good people are not rich.

[@bobbobson4030]

Is it publicly available? Doesn't it have to be FDA approved first?

[@Earth_Engel_333]

I offer myself too practice on My body

[@rajpriya1437]

when available limb girdle muscular dystrophy treatment for Gene therapy

[@brienq]

The video title was about Gene Therapy for Human Ageing | Elizabeth Parrish, so why does this start out with NAD and mice ovarian aging? Seems nothing to do with the telomerase gene therapy that Parrish had.

[@alexanderbryant8206]

I’d like to see a talk with her and Ray Kurzweil. Kurzweil predicts longevity escape velocity around 2030 because of nanotechnology that would enable treatment delivery on a cellular level. I’d like to hear how Liz’s treatments could interact with that technology to give even better results.

[@johnniejay]

Peter Diamandis has spoken at length about the convergence of disruptive technologies, and their expotential effect on the rate of progress in the field of biotech. Well worth checking out some of his talks if you havent done so already.

[@iansmith3292]

Check out "Immortalists" and you'll see the two main views overlap and from different sides. Bill Andrews is an excellent resource.

[@urbanfightingsexmage7005]

This women is literally a genius enuff said

[@cyberreality7774]

No

[@Science-sans-conscience]

C’est la solution à la maladie bien connue sous le nom de mort. On peut séquencer les gènes des gens dès leur jeune âge et leur réimplanter des cellules pluripotentes pour reprogrammer à un endroit défini pour recréer les gènes perdus. Le côté reverse te lime rase est intéressant. Pour ceux qui n’ont pas eu leurs gènes séquencés on peut leur implanter de nouveau genes ? Peut être les rajeunir avec de nouveau gènes s’il n’y a pas de rejets

[@timothykaliszewski7459]

Are we getting closer?

[@tomc1121]

If she is patient zero where is the data for patient 1,2,3,4,5. Oh I forgot it cost $75,000. But where is the data?

[@DarqeDestroyer]

Do these technologies just extend life, or do they also preserve physical youthfulness? There wouldn't be much point in living for 200, 500 or 1,000 years if you were still decrepit by 80 and remained that way for centuries.

[@KasirRham]

From what I've seen these treatments are more focused on health span and keeping people healthy and functional. The extension of years of life appears to be a side effect of intercepting/repairing the cellular damage.

[@leiladasha]

age reverse to 30

[@iansmith3292]

Age reversal by -20 years, but you have to take it every 20 years. Liz Parrish is currently involved with a monthly nasal spray using a different (but safe) viral vector that makes no genetic changes. I'm a bit crazier and went for eternal youth with no addition treatments required.

[@Val-zx7ro]

keep going :)

[@minibabita2285]

I think this company pramotion may it's not that help for ordinary people because it's too expensive

[@Wenaspapus3]

El ser humano empieza a envejecer a los 33 años cuando la cadena de telomeros se rompe. Al romperse los telomeros el ser humano empieza a envejecer lo que hace que el envejecimiento sea una enfermedad y se puede evitar si se logra genéticamente que las cadenas de telomeros no se rompan. Saludos

[@luismiguelmartinezsanchez4069]

se empieza a envejecer a partir de los 60 o 65 que es la edad de jubilacion no es posible que a esa edad los telomeros empiecen a acortarse a mi me dijeron que se acortan desde que nacemos

[@chrisellacole9951]

How sure are we that she is not jus a lady with great Gene's exaggerating the the use of gene therapy 🤔

[@larapo8691]

We are sure because her biomarkers changed to the level of younger people. It was verified by blood tests.

[@angiep5216]

She is not the only one, David Sinclair is another biologist who is creating a lifespan. The problem is the overpopulation in this planet, so the population will go higher with a long lifespan. Good for people but very bad for the planet. Too much contamination, pollution, etc

[@craigsilver2146]

We already have healing and eternal life through Jesus Christ our Lord. 1 Peter 1:3. Blessed be the God and Father of our Lord Jesus Christ! According to his great mercy, he has caused us to be born again to a living hope through the resurrection of Jesus Christ from the dead. John 3:16 KJV: For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life. Luke 6:19 And the whole multitude sought to touch Him, for power went out from Him and healed them all. Hebrews 13:8 Jesus Christ is the same yesterday, today, and forever.

[@arsalanmohammadi6169]

You Galilei savage anti knowledge priests offspring’s 🤮

[@fourthz4460]

She is so beautiful. Im 23 yeas old, i never thought i would be attracted to a 44 year old 😙😚😘❤

[@landonw23]

She is 48

[@guilhermeparreiras8467]

She is 50. Liz was born the 28 of February, 1971.

[@fourthz4460]

@@guilhermeparreiras8467 😮

[@johnniejay]

She is absolutely beautiful, I must agree.

[@rene-rv6pp]

It happens that when you're on your 20th you cant tell the age of people older than you

[@rgaleny]

treat the telomeres of bone marrow !!

[@schneewinter3679]

I have attended a lot of medical congresses and she does not present any comprehensive scientific concept. She is just stringing together random buzzwords which sound exciting. Sorry, but I think this could be fraud.