Mechanisms of Renin Release

[@AliOmar-he5zv]

4 years of medical school, and only today i finally understand what the macula densa and Juxtaglomerular Apparatus finally is Thank you so much man!

[@jseanbrooks1]

Dude, I feel that big time. I'm still an undergrad, but I finally got a grasp on the juxtaglomerular apparatus today in lecture, feels satisfying :)

[@drmohammedashraflone1520]

This we can't expect from our textbooks

[@eugenioasanchezperez1406]

Lol how did u get into second year without knowing that . Proud of you still, medicine is a frriggin rolllercoaster, theres things that still to this day may confuse you. Keep it going

[@aryan7767]

its joever@@eugenioasanchezperez1406

[@kryztalacuna]

I almost think every medical student lowkey knows who Armando Hasudungan is

[@delight_l4127]

Of course :)

[@scarletjazz8309]

Well don't they?

[@Yousefmmohammed]

*highkey ✌💖

[@drmohammedashraflone1520]

I still have great regards for this teacher( M. Ashraf.... consultant emergency medicine... India...

[@SingZeon48]

'And I'm not gonna talk about it in this video' - damn, what a tease!

[@ColdWarVet607]

Should be Titled "Fantastic Drawings of Anatomical Guts & Explaining the Near Unexplainable in Simple Terms" Bravo my friend!

[@sukhendupramanick1661]

I am a student of B.Pharm from India. All of your videos are totally understandable and very helpful for me. Thank you sir, for your efforts.❤️❤️ I search your video of related topic most of the time, before studying any chapter of pharmacology. Once again thanks...

[@saniyasaiyed]

Thank you so much!!! Its because of your videos that I passed my first semester of med school! and now I religiously use ur videos to revise for my next semester. Keep up the good work :)

[@sobialaghari225]

Explanation + drawings = perfect

[@shankhamitrapaul6370]

The drawing was soooo soothing 🥺

[@HadeerSinawe]

You are excellent, per usual. Keep in mind: Renin (ree-nin) = enzyme for RAAS Ren-nin (ren-in) = enzyme for making cheese ;)

[@asheikh2561]

damn homie u can draw

[@F-bot]

just a tip: your handwriting is not legible.

[@1000cher]

I have to say, your knowledge, drawings and videos are AMAZING!! and they have literally saved my (Biology) life!! I've watched so many of your videos and the have helped me pass the most difficult class in my University life. My professor doesn't lecture AT ALL and we have to learn a whack load of new information every week and have a verbal lab evaluation and a test on new material every week - plus Midterm and Final of course, so you can imagine that it is difficult to learn something that seemingly comes across as foreign at first, really fast and every single week. THANK YOU !!!! By the way, do you sell your drawings? I would LOVE to have some on my wall......

[@maryjhonson2724]

hello 1000cher ,have an 🍨 icecream sometimes ,you been studying , a lot

[@jooahreyes8172]

I love your videos super much! Thank you for helping me and all other students. You made A&P so easy and fun!

[@IsnEkin]

Hey Armando! Super video, you are the hero of the poor science and med students from all over the world :) One question/correction only: As far as I know, the cells that you have named should be extraglomerular mesengial cells. However, the juxtaglomerular cells that produce renin are the differentiated epithelial cells of the afferent arterial (their muscular layer on tunica media is different). Please contribute, guys :)

[@TheMythogenic]

Sen bir ineksin

[@omumedicine2904]

yess ure right

[@DrOscarPacheco]

Exactly. There's a confusion here. It's the INCREASE in sodium content (tubule) that triggers renin secretion (renin will "correct this loss" and elevate pressure)

[@LindyFordNutritionWellness]

Excellent video. Great illustrations. Helped me to understand the system more extensively. Thank you.

[@carlaoberholster244]

thanks for helping med students all over the world!!

[@drmohamedraslaan7989]

It is simple easy with more illustrated, thank you so much for your work

[@Dani-gu6bm]

liked that subtle "substance, well, substrate". That means you put interest at accuracy. Great videos, so much talent.

[@keitzatumai]

your drawings are sooooooo helpful!! thank you!!!

[@김대원-g1v]

thanks all of your video really helpful.for my endocrinology mid term and final term

[@AALEJANDROCC]

I really enjoy watching your videos. Thank you for doing this!

[@Lindz37]

This has helped me sooooo much as a student!! thankyou!

[@lukecho9225]

Excellent explanation and pictures! Really very well done. Thanks

[@ruthanna4713]

love your drawings, thanks millions - so helpful

[@jhonmoon3316]

It’s brain reliever❤️

[@madil2259]

thank you. armando. your videos are the best. thanks for the effort you put into them.

[@istigern]

This helped me ALOT. Thank you so much! I love your videos.

[@josephineani4872]

thanks that was helpful. i have a test on urinary tomorrow and i have been struggling with renin. thanks

[@dr.subodhmazumdar6994]

I am very happy to see your video as i read it in text book forty years back.

[@ilaila3504]

absolutely amazing and clear thank you!

[@waqqashanafi]

YOU-RINE!

[@Motorcyclegymnast]

UROOOONNNN XD you saved me in my endocrinology class thank you!

[@absbse]

Excellent video, very well explained, (better explained than my phd teacher who just confuses me) I have a question, are angeotensinogen and angeotensin 1 and 2 all hormones ?

[@Submersed24]

I'm not even a medical student, just here trying to solve my blood pressure problems lol

[@onyxgan9923]

Whoa ur diagrams are brilliant!!👍

[@NostressAdi]

This was so so helpful! Thank you so much for making this video!!!

[@APOSHCAWADAS]

An excellent video!!! Congratulations.

[@frederikscience]

So both baroreceptors in the afferent arteriole AND in the aorta can stimulate renin release by detecting changes in blood pressure? Is my understanding correct?

[@treenamahant7331]

Thanks for sharing the video and drawing with me #PicassoArtwork # priceless

[@parvathareddychandrahasa2957]

You are videos are so helpful

[@prernasharma7671]

Such amazing diagrams, does he use any app or make it on paper

[@1lynn1]

Thanks so much for these videos! You are helping get through school.

[@sherenbaloum7127]

Thank you so much , its very helpful

[@Just_An_Idea_For_Consideration]

This is an amazing channel!!! Thank you!

[@azizmohamed9059]

Amazing as always

[@robertheinrichs4273]

Mr. Hasudungan do you have a video that explains the release of erthropoietin or EPO also known as hematopoietin from the kidneys. I enjoy your videos.

[@biswajitnath804]

5:42 passing through dct means to blood or into collecting duct?

[@charleexiong1601]

In dct, macula densa cells (chemoreceptors) detect the low [Na+] and [Cl-] (from filtered blood) which stimulates the juxtaglomerular cells to produce/secrete more renin into the blood.

[@genericalias4805]

Thanks for making those videos! Just one small thing: from what I've learned in University the macula densa cells are (although right at the border to the distal convoluted tube) still part of the thick ascending limb of the loop of Henle.

[@kca7695]

*At the junctn of DCT and thick part of ascending Loop of Henle

[@AdamRich47]

I am not being overcritical. That drawing is amazing. I wish.

[@setonhillsoma3962]

can you explain how a decrease in [Na] in the DCT/ macula densa causes renin release, because renin eventually causes an increase in aldosterone and Na reabsorption which would lead to a further decrease in Na in the DCT, this would appear to be a positive feedback loop but I don't think it works like that

[@jjarrell1010]

Pure genius! Thank you for what you do!

[@goldenheart4478]

Appreciate your extremely nice video. Everything was delivered ❤❤❤

[@armandohasudungan]

Thank you so much 🤗

[@sihembenghalia5596]

Thanks a lot this really helped me 🙏

[@anaverageuser9330]

thanks armando

[@gopinathnatarajan6684]

Sir , can you put a video on action and resting potential of nerve impulses please

[@BBCeiz1993]

Thanks armando you are very good

[@hanniballecter9592]

Armando, your videos are priceless and always worth watching. If I had one comment to suggest improvement it would be to polish up the language you use to make sure it is always accurate, e.g. convulated isn't a word and actually using the correct word, convoluted, helps to remember it because the tubule is indeed a convoluted shape. Aside from this minor point, this is another superb video, thank you.

[@germ9337]

I suggest you listen to Dr. Lecter, Armando.

[@kamanashisroy]

Thanks. We can have a healthier life just by knowing our body. The work of diabetes and renin-ang system should be in our school book ! In that way we cannot blame the lack of knowledge for our misfortune .

[@theowleyes07]

It is

[@lih7542]

excellent as usual ..many thanks

[@davidfreiholtz6711]

Great video, but I can't quite seem to get my head around the fact that you state BP is the main contributing effect of RAAS-activation. To my understanding, this system is mainly a response to decreased effective circulatory volume (Boron & Boulpaep). That sympathetic increase in BP would confer decreased effective circulatory volume seems contradictory to me. I might have gotten it all wrong from the start, but if you are able to clear this up for me it would be greatly appreciated!

[@gangamishra747]

Excellent drawing 👍👌👌

[@mohamedbadran2652]

I really enjoy your videos thank you so much :)

[@cynthiac6750]

This was beautiful

[@mrscrystalbear]

You rock ! Thank you for being so clear

[@elamariinas7680]

Thank you very much! GREAT JOB

[@msoccerplaya12]

Great video! i have been using your kidney and nephro videos to help fellow pharmacy students to prepare for volunteering at a camp for kids with CKD through the NKF. Thanks for your work.... any chance you can upload the google image??

[@coldasice7x]

are there pdfs of the final picture we can print?

[@Bananamello]

I'd love one too. His drawing is awesome

[@bmdskin]

Congrats for this video! 👏🏽👏🏽👏🏽👏🏽

[@thirva95]

Your videos are always helpful sir :)

[@adeelurrahmankhan1801]

Sir pls make video on creatinine synthesis and how phenylacetate and banzoate effect creatinine and urea formation.thanks a lot for brief explanation

[@DariaKsen]

So great, thank you for your video

[@mohsinfareed1797]

GREAT, GREAT AS USUAL. THANKS.

[@maryjhonson2724]

Hola Armando ,were can I get some of this drawings ??

[@amayaparanagama8205]

whoever it's very usefull...and thank u so much....and need more☺☺☺☺☺

Thanks a lot for that explain! Besides, I really loved your drawing :)

[@jowanaaltabish5273]

you're great man thank you so much

[@hamzaw.2288]

the illustration is great but you're kind of wrong with the location of ACE. It's on the membranes of pulmonary vessels not in the alveoli. source: UWorld STEP1

[@CryptoShinobi27]

Now you are my Master :D

[@eddq-o4232]

Dude you are the best thank you

[@A19XI4BX]

Thank you!!

[@aydnmhsn]

there is loop of henle which is essentially a... loop. That's it. This is the simplicity I want in medicine.

[@simpl6775]

thanx a lot!

[@حيدرمحمدحسين-ض3ه]

Thank you

[@parassolanki9780]

Hey can we get these flow charts?? Make a book and make it available on Amazon 🙏🙏

[@ommoawiaisa]

ممتاز فعلا فين رابط الصور بتاعة الفديو بقي :) ؟

[@tejaswinibasuthkar6252]

Tq sooooooo much sir 🙏❤️

Gorgeous!

[@taylorwhite3636]

I don't feel I've ever understood how the RAAS system becomes chronically and pathologically activated. The two big mechanisms mentioned here seem to be renal hypoperfusion and hyponatremia. In either case, it seems like it would be quite a bad idea to inhibit the RAAS system with an ACE-I or ARB. Still quite confused.

[@jessib213]

Very nice 👍

[@blackcahyo22]

thank you so much! your videos are cool 😙😙😙

[@fareehazafar863]

the angiotensin converting enzyme is located in endothelial cells in lung capillaries

[@sanadal-soub540]

excellent

[@nasrullahkhan5639]

I need these leacture notes please.

[@jenniferettinger4943]

Lol you sound like a pilot talking through the speakers

[@nafeesashah7363]

THANKYOU SO MUCH SIR...ALLAH BLESS YOU :)

[@mekalababu1233]

Thank u sir

[@Yousefmmohammed]

I just can't thank u enough 💖✌💫💫💫💫

[@DreamSpaceInfinite]

wish i seen this about three hours ago before my path exam lol

[@shrabanimukherjee5347]

Fab-you-lous❤❤... Thanks

[@razansw9726]

you man are awesome :D i love your work :) keep on the hard work and thank you. best of luck :D

[@jonas9788]

thankyou

[@gskylexkk7280]

How to turn off the renin release through negative feedback ?