Methylene Blue (MB) Dosage and Administration Approaches

Numerous studies have shown the neuroprotective effect of methylene blue (MB). It seems that MB can be used for brain fog, confusion, memory issues, and mitochondrial dysfunction in neurons. In this talk we will look at the practical aspect of methylene blue administration.
DrBeen: Medical Education Online
www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
covid19criticalcare.com/
URL list from Friday, Nov. 18 2022
Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue - PubMed
pubmed.ncbi.nlm.nih.gov/22067...
Frontiers | Protection against neurodegeneration with low-dose methylene blue and near-infrared light
www.frontiersin.org/articles/...
Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
A two-year double-blind crossover trial of the prophylactic effect of methylene blue in manic-depressive psychosis - PubMed
pubmed.ncbi.nlm.nih.gov/3091097/
Methylene Blue: Generic, Uses, Side Effects, Dosages, Interactions, Warnings
www.rxlist.com/consumer_prova...
Methylene-Blue-Cognitive-Vitality-For-Researchers.pdf
www.alzdiscovery.org/uploads/...
Methylene blue Side Effects: Common, Severe, Long Term - Drugs.com
www.drugs.com/sfx/methylene-b...
METHYLENE BLUE - ORAL (Urolene Blue) side effects, medical uses, and drug interactions.
www.medicinenet.com/methylene...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

[@mudslinger888]

I take .5 to 1mg per kg daily. I also take NOW brand Cilantro/Chlorella tincture, which crosses the bbb to pull out heavy metals. Even though I take the fish grade at 1.15mg/drop, a recent blood test flagged me for being LOW in Arsenic! I am not worried, as I am also a willing tester who takes the risks. When you have a neuro-muscular disease related to polio (ME) you will be willing to sacrifice quite a lot of safety simply to have a life. MB works lke no other supplement I have tested, and I have tested over 100 items over the past decade. I also found that a pastured ruminant-based diet is by far optimal for me, nothing beats especially liver for nutrient density and availability, it is astounding help. I also now get big midday sun year round for the IFR. I have and use several lights, but nothing compares to the actual sun, especially midday sun sufficient to retain a tan works for me so well. I actually built a solarium to lay in through winter.

[@yogimaster1]

I would NOT take fish grade methylene blue, ONLY pharmaceutical grade, for internal use.

[@paulroach0217]

You mentioned you take MB fish grade? If so, what is your experience? Thanks.

[@yogimaster1]

@@paulroach0217 If you want lots of mercury, lead, cadmium and other heavy metal toxins, go ahead and take MB fish grade.

[@shantinaturechild3239]

@@yogimaster1 l found a fish medicine methylene blue that is < 99% pure and costs 80 times less than pharmaceutical grade.. I will ask them for a certificate of analysis and compare to USP grade if they give me one. I don't like getting ripped off by those people making lots of money from sick and suffering people!

[@yogimaster1]

@@shantinaturechild3239 Do your research thoroughly and carefully before putting fish grade MB into your body. You should see a pretty big difference in the heavy metal content between fish grade and pharmaceutical grade MB. All I can tell you is I'd never take fish grade and I'd even be cautious about pharmaceutical grade. Search KZbin for "Nootropics expert methylene blue" and watch his video.

[@chinookvalley]

I hope this becomes mainstream soon. My neighbor and best friend killed himself 19 mo ago, paranoid schizophrenic. I feel he would have happily tried this just to see if his PTSD and other nightmare effects from the VietNam war would have been lessened. We have so much at hand to help us, but doktors can't tell us what might help.

[@kathymayes4290]

Really sorry.

[@ABC-qd1ei]

Lions Mane mushrooms for PTSD.

[@JessicaSilva-pu5hj]

Thank you Dr. My mother has alzheimers and it's on MB low dose, she has had and continues with improvements... along with supplements, brain peptides and healthier eating ... can't deny it works a lot not just some

[@JessicaSilva-pu5hj]

@@user-yn9nw7km2l try to get him quality because many contain other chemicals that can be toxic

[@i.ehrenfest349]

@@user-yn9nw7km2l let us know if it works, ok?

[@randallhesse5011]

Supplements?. Let me guess which ones, maybe he shou wu (polygonum multiflorum) or maybe yuan zhe (polygala tenuifolia) or maybe Chinese club moss (huperzine-A) or maybe cistanche, or maybe cats claw, or maybe passion fruit seeds (piceatannol) or maybe holy basil?

[@JessicaSilva-pu5hj]

@@randallhesse5011 none of those

[@JTDesign1]

Dr. Been, What I find so interesting about this 'blue dye' is how helpful it is to overall cellular function and especially the neuroprotective effect you clearly explain in your video. Shortly after watching these wonderful video's of yours I ran into a coincidence that is hard to ignore. I'll just say I don't believe in coincidences either. Nature just publish this interesting article about a green dye developed by Kodak in the 1950's: The CRISPR-Cas9 gene-editing tool might have cracked the mystery of how death cap mushrooms (Amanita phalloides) kill - and it led researchers to a potential antidote. Using the gene-editing technology, researchers created a pool of human cells - each with different genetic mutations - and exposed them to the mushrooms’ toxin. The toxin could not enter cells that lacked a functional version of an enzyme called STT3B, and cell survival increased. The researchers then sifted through thousands of chemical compounds to find one that would block the action of STT3B. They uncovered indocyanine green, a dye developed by the photography company Kodak in the 1950s and used in medical imaging. Indocyanine green has not yet been tested as an antidote in humans, but it reduced deaths when given to mice. Is all this positive information on 'color' the reason my mother always told us to eat the colors of the rainbow??

[@creativesolutions902]

I often pondered the relationship between color and Health… and why is our genetic molecule called a chromosome?? (Chroma meaning color) Color is very important to human health.

[@adamfalgout6601]

Beef and salt (carnivore) is the healthiest food for the human body long term. Go look at Dr Jordan Peterson and his daughter.

[@JackMili]

I am a dentist. I use Low Intensity Laser with methylene, aka PDT for treatments im my practice. This video shows a serious and professional aproach about the theme(linking the researches). Thank you very much for the information!

[@SamanthaSweetAnne]

What is the benefit to this into your patient's know ahead of time?

[@VICTOR21121966]

Can you put also a link with a study or information how this is done. Thanx.

[@carloscarion1748]

Hi swish methylene blue around in my mouth each morning my teeth and my tongue turned blue but I think it’s some help in my daily oral care, what do you think? Where are you located, I am looking for a new dentist

[@JackMili]

@@carloscarion1748 I'm from Brazil. South...

[@carloscarion1748]

@@JackMili How do you use methylene blue in your practice?

[@barbarahollingdale8064]

I started taking it for my cancer

[@yeshua1122]

Another thing that works for cancer is Chlorine Dioxide.. also called MMS.

[@LarryPham64]

Thank you thank you for doing these sets of videos on Methylene Blue

[@ms_amanda2714]

Thank you 💙 perfect timing, I'm just starting this flccc protocol today

[@sandraedlinger4663]

The best Video on KZbin about this subject. Thank you very much.

[@gearyheidinewaccount3237]

Thought I would try it with all these positive videos and reviews..one drop and bad abdominal pain and bathroom visits

[@naturalsleepcoach42]

FYI even regular pharmacuitical products also have impurities.

[@massageistherapy]

TRUTH!

[@094340]

At MUCH lower levels.

[@DANTHETUBEMAN]

even multivitamins have them. 😮

[@capnceltblood5347]

Would not make sense to have contaminants in the fish store MB.. who would use it if it killed the fish XD... Think about it... a person would be libel if the told people to use non pharmaceutical MB...

[@user-jg2bw2et4f]

Ya not wrong and harmful side effects

[@Bellab1x1y1z]

Thank you - Your take is Most Superior!

[@Silver0426]

Thank you!

[@nipagandhi7251]

THANK YOU !!!

[@the1stime]

Great lecture. In my observations there needs to be more studies done on low dose MB. Anecdotally I’ve seen so many people benefit from starting low (ie 1 drop/0.5mg per day) and slowly increasing. I find the traditionally recommended amounts too much for many people.

[@DSmith-ix1xf]

True. It's easy to state an amount, but the cure is in the dosing.

[@philipyaro]

what is your perfect dose?

[@the1stime]

@@philipyaro the perfect dose is individual. There’s too many variables from person to person (toxicity, mitochondria status/pathways, thiamine levels, etc). The best we can do is start low and observe. Increase from there if needed.

[@philipyaro]

@@the1stime Thank you! I'm going to reduce ...I start taking it ..and it is too much.

[@SallySamsara]

Good luck finding an excellent Certifcate of Analysis for MB. I have looked at Infuse-Serve and what used to be Hopkinton. A couple yeas ago the CoA were NOT impressive. Getting heavy metals out of one's brain is a big challenge.

[@casemiro3594]

Excellent explanation. Thank you!

[@natashaservo]

Thank you for this great MB info!

[@manyBlessings2all]

Thank you, helpful info

[@shantinaturechild3239]

Best and most important presentation of all l could find on . methylene blue! Thank you!

[@musimedmusi8736]

I would suggest that if you’re going to do MB, take supplements known to facilitate heavy metal detox. There’s “Modiflan”, made from a kind of brown seaweed. They used to advertise it as detoxing from heavy metals; they withdrew that claim but the product is still available. (You know how picky the FDA can be about any kind of claims.) That’s just a beginning suggestion for persona research. Discussion: One of the things most helpful about Dr. Been’s presentations is that he provides a more comprehensive inventory of necessary information than perhaps any other online lecturer. It was helpful to learn of the potential contaminants, arsenic, lead, mercury, cadmium, aluminum impurities. We should not automatically overlook the fact that there is really no safe dose of lead, to begin with, nor, in the opinion of many, mercury (note the thimersol controversy). And aluminum, arsenic and cadmium are not exactly friendly. Many people work very hard to detox from all of these heavy metals, so the question of safety issues over ingesting even “negligible” amounts deserves discussion. What amounts are we really talking about? Are they significant below background levels we ingest anyway from the environment? In that case, for instance, an argument for safety might be made that taking MB chronically will not raise a person’s heavy metal load meaningfully above what they’re already carrying. Or the the amounts in MB might be above background, etc., etc. An example of another side of the issue whether simultaneously facilitating the *excretion* of heavy metals might be sufficient to overcome expose from MB impurities. I had a colleague whose family criticized her for eating too much tuna (sushi). Her dietary regimen was otherwise very healthful; e.g., lots of seaweed, tons of vegetables, pure organic food, etc. The whole family got tested for mercury levels. Hers was very low, despite the tuna, while the other family members had a more typically high level. So, a healthy body can deal with a certain amount of exposure to heavy metals. The question then would be, what kind of supplemental heavy metal detox regimen might go hand on hand with taking MB? More discussion is needed, not glossing over it as the cited study seems to do with “of no great concern”. “Of no great concern” is not exactly what one would characterize as *due diligence*. This is not a trivial issue.

[@Eyes0penNoFear]

I take food grade Diatomaceous Earth and activated charcoal to help with heavy metals. I'm just beginning to learn about MB, and I'm very hopeful it'll help with LongC and ME/CFS issues 🤞

[@anastasioselgriego.1142]

6667😊 iv

[@sekhmet1290]

read andrew cutler... ex: many autistic kids have mercury but on the hair test it will show nothing at all, while a healthy kid will have some. why? because the kid that has the autism can't detox so he gets very toxic, and the other kid has the capacity to detox after every exposure and it will show up in hair test.

[@traceykays433]

Be careful to not detox to often for heavy metals because it can stip u of many needed minerals u must have.

[@Karyabs]

Where do these heavy metals come from?

[@jeffrey4577]

Im trying bucal troches from troscriptions at low dosage first and discussed with my internal med Dr .

[@luv2travel2000]

1:55 Dose for neuroprotection is 0.5 mg - 4 mg per kg body weight. Best to lean towards lower dose. 2:50 Contraindications: G6PD deficiency should NOT take this. NEVER give to pregnant mothers.

[@redwoodsorel5173]

What is G6PD?

[@luv2travel2000]

@@redwoodsorel5173 Not sure. It's mentioned in this video.

[@luv2travel2000]

@@redwoodsorel5173 Someone in the comments for this video said it is a blood test you can get from your family doctor.

[@PlainJane1421]

How are these measurements converted into drops?

[@soakedbearrd]

Seems excessive. For instance the brand that I have is 10mg per 1ml (about 20 drops or 0.5 per drop). I weigh around 85 kg, so that means even at the lowest dose, I would have to take 42-43 drops daily. Anyone that has used it knows that 2-3 drops completely overwhelms anything you add it to (color and taste). I don’t know, it just doesn’t add up. My bottle cost just under 30 bucks, at 59 mil. I’ll stick with placebo effect of 2-3 drops daily with my shake lol.

[@AllThingsConsidered333]

MB also very effective against stationary form Bartonella & biofilm. Most Drs who use this treatment recommended the liposomal capsules from compounding pharmacy but I can’t find a CP that makes it unfortunately. Now Bartonella rearing it’s ugly head so I saw my dr today and I’m back on MB as well as 3 antibiotics starting tomorrow. Rifampin/methylene blue is a recommended combo for persistent Bartonella. I’ll also be taking azith & clarith. I use the USP grade 1% liquid from compass labs. Currently at 10 drops and increasing. Dr Burrescano says it’s important to take antioxidants while taking larger doses MB as it causes severe oxidative stress. The talk was on Project Lyme channel “examining Bartonella”. I read research last year showing MB great for neurological conditions/diseases, Bartonella, babesia, and more… Tick diseases really suck.

[@nope9628]

cipro? yikes

[@AllThingsConsidered333]

@@nope9628 I’m sorry not cipro! Clarithromycin!

[@Jennifer-gr7hn]

so does having it along with long covaids, post stroke with no help, mold toxicity and a hole in the heart. MB cleared my candida and lyme :) Now, the longcovaids...which was far worse.

[@tigerspiritjourney]

@@Jennifer-gr7hn Hi! How do you know it cleared your Lyme? How long did it take with the MB? Hope you feel better!

[@michelemcneill3652]

I have ME and am very excited about trying it.

[@tlkendall29]

I just received mine as well! Excited to try it as well!

[@PraiseHim123]

How are you doing? I have ME as well

[@michelemcneill3652]

@@PraiseHim123 I have been on methylene blue now for at least 2 weeks. It's amazing. I take 3 drops which is 1 1/2mg 3 times a day. I have more energy and so much less brain fog. I am also sleeping better. For me I felt on edge and blood pressure went up slightly at 4 drops. I ordered another bottle because I don't want to ever run out. I also bought the book The Ultimate Guide to Methylene Blue.

[@randallhesse5011]

ME (Myalgic Encephalomyelitis) broken down, Myalgic (muscle pain) Encephalo (Brain) Myel (muscle) itis (inflammation) my guess is that when the ailment got its name the person of interest must have had fiber myalgia in conjunction.

[@afifahhamilton8843]

Shouldn't the word be 'hormetic' not 'Hermetic'. Hermetic alludes to the Greek god Hermes. Hormesis is the ability for toxins to up regulate anti-toxin processes. Am I right?

[@marnamiller9773]

PLEASE do a presentation using measurements pictorials. A spoon, cup, measuring cups side by side in order. I can't follow.

[@fluffychenille]

I feel the same.....I just am not into this metric stuff. I need cups, and spoons etc.

[@exxzxxe]

Excellent presentation. I have read (not in peer-reviewed source) that there is a negative interaction between methylene blue an nitric oxide. Comments?

[@jazzsnare]

What dosage is advised in the case of TIA or suspected stroke or myocardial infarction? AND, most importantly, if TPA is administered following this, and perhaps they don't know if you took MB, would TPA be dangerous in this combination?? Please respond.

[@gregoryjacksonsr7452]

Would taking zeolite be advised while taking mb? Or would it detox mb out? Is there a difference or kinds of methylene blue or is it all the same? Appreciate the help. Have had Morgellons for over a decade and hear both zeolite and mb will help a lot.

[@mfrmll3786]

How dreadfully awful!!!!!

[@Morgant513]

@@mfrmll3786Why do you say that?

[@harindersingh517]

Sir your views on probable role of oral methylene blue in multiple sclerosis.waiting for your opinion thanks

[@paulbork7647]

Thanks Mobeen. At 15 minutes the generic name and not genetic name is methylene blue.

[@apacur]

Which MB do you suggest?

[@jarose29]

My daughter has cancer and was given ifosfamide and had a bad reaction to it. She has a psychosis episode. She did not know what was real and lost function of her body. They gave her methelyne blue to counter act it and it worked for one day and then she reverted back 😢and is still in the reverted state it had been 1 week already they gave her MB along with olanzapine then took her off olanzapine and MB because she got worse and just put her on seroquen and still no help. We took her off everything now except thiamine and still waiting for her to get better. She is unable to talk and her memory is in s loop we have to tell her that she is real and it’s not a dream every few hours.

[@Leroy91]

I am so sorry to hear that. It occures because of toxic effect on the cns. Methylene Blue was a good choice. I couldn't find much about it's mechanism and why it happened. As an alternative you can star using anything that helps the body detoxify like Melatonin (Antioxidant) at night, artemisia ( antiinflamatory but also produces NOS that kills bacteria).

[@c-hawkins4358]

I’m so sorry this is happening to your daughter. Sending prayers.

[@robpoindexter]

You and your daughter have been prayed for. God loves you and your daughter much more than you can even imagine. Jesus will help your family through this if you ask him to. Please hang in there and don't lose hope.

[@huviba5826]

For cancer you can try - Fenbendazole-

[@guflportgyrl]

Prayers for your daughter! I pray she is healed very soon.❤

[@sherrye5018]

I would like to know if taking methylene blue and zeolite is safe? Or will the zeolite make the MB useless?

[@birage9885]

Dr. Beem, what is the relationship between methylene blue and hydrogen inhalation therapy? Are they antagonist or synergistic to each other?

[@trinitario6573]

Big question! Currently, I am taking methylene blue, but I am about to create an HHO inhaler. They could become synergistic, since both are electron donors. I will be waiting for an answer that clarifies it. (Translated by Google)

[@kristfur]

@@trinitario6573 Let us know what you figure out. Very interested.

[@erinmoug5075]

I experienced peripheral neuropathy based on suggested dosage.

[@rebeccaanderson4445]

This is likely to be a detox symptom

[@roblovegreen]

in long term animal studies methylene blue has demonstrated some potential carcinogenic activity

[@dapemarots7583]

Where to buy the best grade quality???

[@javaxp1]

2.5mg of sublingual dose twice daily is enough to show results

[@rigaleb]

How do you know you don't have the condition that puts you to the risk of hemolysis?

[@brookstorm9789]

Hi, There is a blood test to check the level of G6PD. Check for deficiency I think. Not sure how to interpret the test relative to MB but that's the safety action. Apparently it's rare but you never know.

[@randompiano]

question is how long is the duration of the course? do you take it every 6 days then stop for a day then start again for the next 6 days?

[@leelawson8911]

Is there a conflict/ contraindication for taking Methylene Blue a n d CoQ 10/ Ubiquinol? Thank you.

[@coppulor6500]

yes, CoQ 10 interferes with electron transport (well, it also positive affects electron transports but interferes with MB)

[@8754roberto]

Let’s us know if yo figure out

[@wendymccleary1465]

@@coppulor6500 Good to know, thanks!

[@Realism76]

Can I take MB while undergoing chemotherapy?

[@dawnsmith370]

I am researching this now and any comments appreciated. I am 59 female and only known problems is my recent bloodwork shows my RBC steadily climbing and now flagged high and my hemotocrit and hemoglobin has been flagged high for 8 years. Dr is wanting me to go for a sleep study next week something about oxygen🤷‍♀️. Also I have to get a thyroid ultrasound annually , it is enlarged and nodules that needs monitored and I have 2 doctors fighting over whether to take it out •. I prefer to keep my organs and no prescription meds.

[@SupremeODMG]

Did they check TSH? For your thyroid?

[@dawnsmith7896]

@@SupremeODMG THANK YOU for your response. yes checked all my thyroid numbers and tell me all are within normal range. my PTH came back really high once but now it is in normal range again. I have been sent for 3 needle biopsies on nodules over past 3 years and every time my thyroid gets angry and immediately swells to the point to where they can no longer see by ultrasound. I did the sleep study last week and dr tells me he thinks i am having some sort of obstruction episodes, that all my episodes and even pvc's were while i was on my back, that nothing at all happened when i was on my side. so again back to wondering if thyroid causing this as well.

[@ahammer7000]

@@dawnsmith7896 do you take iodine(sodium iodine only) for your thyroid?

[@huviba5826]

You have to donate blood (bloodletting)

[@Morgant513]

Just completed a sleep study, would NEVER recommend and I will NEVER do it again! 30-40 wires attached head to toe! Goo stuck all over you scalp. God knows how anyone is supposed to sleep with all that shit attached! And don’t even think about the issue of getting up to pee with all the wires attached!

[@Teresa-xq5ut]

I found it in a dissolvable strip you put on your tongue. It's 20mg every other day.. Is that safe?

[@minimouse055]

will B3 immediate release niacin effect this product?

[@ronp5615]

Any comments about methylene blue and ClO2 at the same time? Thanks!

[@biker9114]

So at 160 lbs. = 72.5748 kgs. for protection against neurodegeneration and brain fog how many mg of methylene blue would be a low dose> ?

[@MYGAS21]

The problem is ...that this chemical doesn't have milligram dosage indication. It's not a pharmaceutical proper. SO how can I calculate the drops?

[@Rory181redbull]

What are your thoughts on Methylene Blue and Pulmonary Hypertension. A few study authors reviewing MB have expressed concern on its inhibitory action on Nitric Oxide, potentially worsening the PH. Considering a good amount of long covid patients have PH, would MB be contraindicated? "Among 50 post-COVID-19 patients, 30% of patients had normal pulmonary artery pressure, 30% had pulmonary hypertension with PaO2 ≥ 60 mmHg, and 40% had PH and RVD with PaO2 < 60 mmHg"

[@kenhnsy]

I have found combining MB (30mg/day) with NMN (500mg/day liposomal) to have far better energy and mental concentration effect than either by themselves. Can you comment on this? Wise? Stupid? Imagined?

[@laurafuller8528]

I have noticed this too! They seem to enhance each other.

[@simonleland2873]

Seems reasonable

[@pandakashikuka247]

Can GERD patients use MB is it safe? The dose for GERD patients please.

[@SevenThunderful]

I wish I could take this. It gave me a lot of energy and mental clarity. However after a few days I developed horrible peripheral neuropathy, which went away as soon as I stopped.

[@laurafuller8528]

Interesting. My legs feel less heavy taking methylene blue.. lighter, more vital, more sensitive in a good way.

[@SevenThunderful]

@@laurafuller8528 Maybe the brand I'm taking is bad, but it does have a chemical certification.

[@eLiV8t]

What dose did you take? Ive been experiencing trigeminal neuralgia and dont want to aggravate it.

[@SevenThunderful]

@@eLiV8t I ramped up to 6 drops twice a day for a total of 12 drops. I believe that's 6mg of actual MB, which is still considered a small dosage. I want to try maybe a smaller dosage for a while, but like you I fear the neuropathy more. There are other factors of course, like is my product actually pharmaceutical grade or a Chinese knock off. It does have a supposed laboratory certificate though....

[@Morgant513]

@@laurafuller8528What dose do you take please

[@janetcrescioni6822]

Can I use the MB for the acuaryum

[@galladiel]

Thank you so much! I am assuming they are talking about powdered Methylene blue. Where I live they only sell 1% solution for external use, but still medical grade MB. I guess I need to do some calculations. My friend used 5 drops of 1% solution in a glass of water twice a day to treat you know what last year. It made the water very blue. Almost spooky to drink. I wonder how many drops would make a dose of 1mg/kg. I am guessing more than 5.

[@Jojo-in1wx]

I’ve read a lot that lower doses are very helpful. THe liquid is usually .5 mg per drop. That would mean you would have to take two drops per every 2.2 pounds you weigh. Way to much in my opinion. I take ten drops twice a day which works great for me. Less is more.

[@sonofjay817]

@@Jojo-in1wx Yeah, I just started taking it yesterday myself. Mixing just 0.5mg/kg of bodyweight (I actually estimated my lean body weight and used that number) is a bit spooky to me and I'm paranoid I'm not calculating something right because it just seems like too much. So based on 70kg lean bodyweight, that's 70 drops (one drop being 0.5mg). Yet Dr. Been says people have benefits from one drop a day. Seeing dosages with that much variance makes me nervous.

[@dzikdziki2983]

I have a 1% solution too. I weight around 80 kg. 1 drop is around 0.5mg. So... 80x0.5 = 40 mg. 40 mg per 0.5mg a drop is 80 drops. Minimal daily dose. Thats allot. 4mg/kg would be 4mg x80kg =320 mg. 1 mg is 2 drops so 320mg x2 = 640 drops XD Thats insane.

[@richardmalone3172]

To treat you know what? The virus? I take MB. I dissolved 1 gram in 100mils of water. I take 1 mil daily in a glass of water. At the concentration I use, that means 1 mil is 10mg of MB daily. I take it through a straw to avoid blue lips. Haven’t noticed anything. No changes in sleep, energy etc. I’m using it to maintain cognitive function.

[@Rittlesleo]

Try dissolving 1000 mg ascorbic acid in water then adding the MB. Drink when clear. I also use a straw.

[@cygnusne]

Thank you for all the info. I read that it is good against the corona virus. Do you know if it is helps with long covid ?

[@Jennifer-gr7hn]

helping me!..severe covaids march 2020, and was dear death, then near 'ending it' myself. Year 3, found this in IV form with EBOO..,helping!

[@northernflicker1111]

​@@Jennifer-gr7hnWhere do you get it administered by iv? 🙏 I'm bedbound since March 2020 with long covid

[@Bellab1x1y1z]

Do you know if we would detox the harmful metals in MB naturally or do they get stored in the brain?

[@kenstrees]

my story..am on only day 4 of a high rated methylene blue drops on amazon, usp grade, Biopharm from the US. .5 mg per drop 5 in am and 5 in pm. Day 2 I had lots of high energy. Day 4 I woke up every hour at night..just couldn't sleep. I usually sleep like a brick. Am afraid to continue it. Any thoughts?

[@Jesse-hk8ls]

Update?

[@kenstrees]

@@Jesse-hk8ls am now taking 10 drops 2x per day with no problems, I just make sure my 2nd dose is before 2pm. I am not sure it's helping me bur it's not hurting and I do get a lot done during the day and I'm 68. thanks for asking!

[@energeticremedies]

I heard to take every 2-4days, when you stop peeing green is when you need more,I sway test to see how many drops and how often my body needs it,I also put it in a capsule per the sway test

[@Jesse-hk8ls]

@@kenstrees thank you. Happy to hear you’re doing well.

[@Cimmaronisson]

Just a thought, don’t take the 5 PM dose. Just take the 5 am dose.

[@AdiArvatz]

I'm taking the mito lab methylene blue which is 0.5mg per drop. Is it normal or possible to have a herx/negative reaction from it? I find it does the opposite of what it's intended for and I usually stop using it pretty quickly because of this. I just wonder if I carry on, will the positive effects eventually come?

[@kristinacoulthread6600]

I just got some from them too and was told to add 1 drop ( not 1 dropperful) to 1 litre of water and drink during the day

[@melanievesters5473]

Do you have lyme disease?

[@AdiArvatz]

@@melanievesters5473 I don't believe so, haven;t been tested though.

[@melanievesters5473]

@@AdiArvatz thank you for letting me know. Maybe you have this gene mutation that causes adverse effects. I m going to try it too. I have Lyme disease and ME/CFS and a lot of other related complicated issues (POTS, MCAS etc). I had traumatic brain injury after an accident 15 years ago and since then I became so Ill. I think there is an enormous brain inflammation going on. I just hope I don't have the gene

[@BaconIsNotBiceps]

I started taking it about two weeks ago. One night recently I woke up at 1 a.m. and was very dizzy and couldn't think straight. It scared the hell out of me. I believe it could have been a herx effect. I've used MMS in the past and got violently ill after a couple weeks on it. I'm continuing on MB with this mindset at the forefront of my thoughts. If the negative effects continue, I'll stop.

[@pankajandfateh9125]

I am taking low dose methylene blue. But I developed a bad ulcer on my palate. Could it be because of methylene blue.

[@CJ-lj9fb]

Does adding vitamin C to the water to counteract the staining decrease or modify the efficacy of the methylene blue?

[@medialcanthus9681]

On another channel, some one commented he/she takes mb with orange juice and it helped.

[@Lauren-vd4qe]

i add the vit c, wait 30 min for the blue color to vanish, then drink it; works fine.

[@loekloekloek]

What is better? IV or oral? I can choose still... anyone knows?

[@SimonRobertElder]

Very good video @Long Story Short but I am still having a bit of difficulty doing all the necessary conversions to find the correct dosage of 0.05mg/kg, as I have a 100ml bottle of 1% methylene blue solution, and as far as I can gather each drop is 0.05ml. I weight about 100kg so should be taking around 50mg which appears to be 5ml, so would about 10 drops be about right?

[@Shoshin777]

I’m so confused too, I weight 90 kg . The mb blue I have is 10mg in 20 drops . I’m lost 😞

[@SimonRobertElder]

I think I've calculated it correctly now. The main problem I had was in not realising mg and ml are pretty much interchangeable, and I didn't know how many ml/mg was in a standard dropper drop, but it seems it is 1, so I hope that helps you too.@@Shoshin777

[@user-yz6sz6wf2q]

take an insulin syringe. 1 ml of liquid is placed in it and is equal to 10 mg

[@simonleland2873]

50 mg of 1% solution is 100 drops. And I think you have a typo in your question. You say 0.05 mg/kg but you’re probably looking for 0.5 mg/kg.

[@simonleland2873]

@@Shoshin777 0.5x90kg = 45 mg. That’s 90 drops of 1% solution. Or 4.5 mL.

[@rhondakennington9634]

Do we place it in water? How is it to be taken? Do we place the drops directly in our mouths?

[@gsica2097]

I am concerned of the contaminants present even in USP grade MB. if they are present even in very low dosages, but you take the solution everyday for the rest of your life, wouldn’t this be counterproductive? To put things into context: I filter my tap water to remove fluoride and other elements even though they are in the ppm levels. We do drink a lot of water everyday, which is different comparing to taking MB solution, though. I’m confused as to whether the benefits really outweigh potential issues long term due to the presence of contaminants in MB

[@partdeux992]

why would you take mb every day?

[@gsica2097]

@@partdeux992 how often would you take it?

[@partdeux992]

@@gsica2097 only when i feel it is necessary. hearing it is a dna intercalator.

[@dzikdziki2983]

You shouldn't worry too much about it. You are taking such minimal doses that the impurities shouldn't effect you.

[@Viertelfranzose]

Is there a alternative Way to get MB in Europe...without the Troscriptions Blocks which I use now. Thanks and greets from Andreas in Alsace /France. Update March 2023.... I found a Source in Australia which works good for me and cheaper in the longrun as Troscriptions MB.

[@trinitario6573]

I live in Spain Could you share the source for Australia? No customs problem? Thank you. (Translated from Spanish by Google).

[@trinitario6573]

In notifications it tells me that you answered me, and I can see part of the text "Trini Tario hello to Spain.. the bottle with Methylen Blue from Australia comes without customer problems to France. The Name on the Bottle is Bluzone. The Address is Miracle". But when I enter I can't see the message. Something happened!

[@aleksandarstojceski3139]

@@trinitario6573 You can find the liquid sold in fish stores in your country.

[@Dippmip]

@@aleksandarstojceski3139 that shouldnt be used as it is not pharmaceutical grade and is likely to contain contaminants

[@tigerspiritjourney]

@@trinitario6573 Hi! I just searched and found the BluZone brand of MB in drops form @ Miracleproducts online shop...

[@sonofjay817]

I wonder if any studies have been done to look at the effect that orally administered MB has on the gut biome.

[@DANTHETUBEMAN]

yogurts help that. 😊

[@wendymccleary1465]

I take about a tsp of red miso every day.. straight out of the container. It's organic and very salty but the good prebiotic effect is preserved. It's working for me at this point.. on 3rd week of methylene blue.

[@nathanwagg1436]

I have the usp grade MB in a 2FL OS bottle in a liquid form for oral use.. i was advised to get some from a lady that owns a hyperbaric oxygen chamber clinic.. can someone tell me what the dose i need to take?

[@nathanwagg1436]

Reason for wanting to try it is because I've had a ruptured AVM on my brain and caused a hemorrhagic stroke..

[@richardmalone3172]

You need to know the concentration of the MB that you have. It should be on the bottle.

[@caulfieldmj]

Did I miss it? How to administer Methylene Blue 🤔 How best to take it?

[@Spark-Hole]

MB is good for focus and energy but my hidradenitis suppurativa aggravated. So I have to stop.

[@DrClay-gf4qq]

How much is Methylene Blue 10-20 mg daily?

[@shdwbnndbyyt]

People in high school & college would slip in phenopthalein or methylene blue into other peoples food or drink as pranks.

[@Shoshin777]

Can you take MB every day ?

[@Rene-uz3eb]

So mb blocks moa A blocking melatonin conversion (as well as seratonin degradation). It seems this will be completely changing the physiology of my daytime melatonin microdosing. Moa converts melatonin to a serotonin precursor in the brain. Edit: sure had the expected effect: I applied mb overnight with vit c only on face, it prevented melatonin breakdown. So def got absorbed by the skin, seems to work. Except the vit c burned my skin, so will have to apply lower concentration or only for a short time. Also the overnight melatonin retained by the mb moa a block was way too much, my voice was very hoarse today which I use as a sign of too much melatonin accumulating. That was with about 0.5mg applied to the skin. Trying lower doses

[@ruthelizabeth9638]

How is it working out using it on the skin with vit c? I would like to try.

[@Rene-uz3eb]

@@ruthelizabeth9638 it made my skin red and flakey, the vit c is too acidic to apply to skin apparently, so I stopped doing that. I'll see if there are other functions of methylene blue. There is some interaction with light, have to read up on that. We know there is a detox effect on red blood cells, for a specific condition.

[@ruthelizabeth9638]

@@Rene-uz3eb Thank You. I think I will try it with a drop of the blue in coconut oil or a cream.

[@i.ehrenfest349]

Dr Been, do you think it’s ok to take 0.5 mg per kg/weight orally if simultaneously taking 40 mg Prozac per day? Going off Prozac is not an option, alas.

[@loveearthspirit829]

No careful

[@joemurray8902]

when you say 0.5 - 4mg/Kg body weight are we talking about the MB powder or already in a 1% solution? And if it is the 1% solution is it affected if added to water and consumed?

[@anguslean4058]

You have to find out how much powdered MB you need to add to a certain amount of distilled water To create a solution of 1%

[@richardmalone3172]

1 gram of MB to 100 millilitres of water is 1% solution. Therefore every mil will have 10mg of MB.

[@dylworksimaginationfactory5165]

I’m still a little confused on dosage. I get the .5-4mg/kg, but how does that equate to each drop. In other words, if I weigh 140lbs, how many drops from an eye dropper would net me 1mg/per kg?

[@rebeccaanderson4445]

1 drop is usually 1/2 a mg

[@johnhurd3257]

Amen. 40 mgs a day or more is what most YT vids say. That's a lot considering it's potent at just 5mgs imo.

[@ibrohimismailov2993]

Thank you very much! Can someone please help me calculate: how many drops of 1% solution per day (I am having troubles converting mg to ml) should I take? I weigh 230 pounds.

[@papasquat355]

You are 104 KG. Dosing is tricky. 1mg/kg or 0.1ml/kg.

[@ibrohimismailov2993]

@@papasquat355 which would mean how many drops of 1% solution?

[@nataliebutler]

A drop of 1% solution is about 0.5ml. Some people take only a drop or two in water and that is sufficient.

[@nataliebutler]

@@josephb3147 I've just started taking it for the same reason. One drop in a glass of water. The first day I took only a few sips and I noticed a benefit. Best of luck.

[@tubegirljwd]

​@@josephb3147 please keep us updated on how it works for you

[@alholds]

Can you give to pregnant men?

[@momohands9086]

Stay away from pregnant men. They are bad luck

[@ktex4873]

Yes, but only in the Pacific NW and you MUST be double-masked. Be sure to write down the first day of their last menstrual cycle, but then erase it (because math is racist).

[@momohands9086]

Pregnant men are the worst

[@martinmaddox5315]

Maybe but definitely not with chest feeding perverts!

[@user-jg2bw2et4f]

Only if there are breastfeeding

[@timower5850]

Critically absent from this talk is how to ingest the recommended amount. If I were to buy 1% MB solution, how many mg of MB are in one drop? This information is also absent from the bottles. Thank you.

[@carlost9454]

Timothy, 1% solutions, one drop = 0.5mgs. I buy mb in powder and make my solution 2%, so each drop is 1mg. I take 1mg per kilo. I am 85 kgs, so I take 45 drops twice a day.

[@ronaldcalandra636]

What’s the best one to buy

[@MartaBotta]

Apparently, CZTL company.

[@Hapkat800]

I am 78 very healthy have controlled high blood with meds since in my 40’s. Just recently noticing my short term memory failing. I’m going to take 1 drop a day in a glass of water & see if I can feel anything happening. I’m very aware of my body. Is it true you need to see it in your urine what if you do not?

[@brookstorm9789]

HI, I'm your age. I noticed I was forgetting things and couldn't get my words out without pauses. I started a few days ago with one half drop. I had been doing a French lesson online and couldn't keep up. After the drop, later that day I was speeding along. My mind felt clearer and my speech was more flowing. Not necessary to have green pee. Good luck!

[@Hapkat800]

@@brookstorm9789 thanks you !….you too!! Let’s Keep n touch Brook..

[@neuroblossom]

how'd you go? i trust in your rejuvenation, good luck

[@user-ye4ss5fg7i]

Can an isuline résistant person take MB?

[@Spiritofnature17]

is this same with MB they're using in aquarium fish?

[@knighttoking7926]

Similar, almost the same. But pharmaceutical grade is used for humans. There are contaminates in the aquarium treatment.

[@Verminator151029]

NO!!!! Did you not watch this video? Anything other than USP or pharmaceutical grade usually has much higher contamination. Even USP/Pharmaceutical grade has contaminants, so DON'T use fish MB...ever!!! Re-watch this video for clarity.

[@ericmaclaurin8525]

dosing info is really unclear given the fact it comes in a 1% solution or 100% powder. A dozen MB dosage video's into my research and I still have no clue if the dosage every seems to agree on is based on the 1% or 100% purity.

[@Shoshin777]

How much do I need to take if I weight 90 kg? Please can someone help me

[@midnightlaundry2800]

If the half life is around 5 hours, then why do I continue to pee green 36 hours after a dose? I took 10mg's, I'm 230 llbs and very active?

[@LauraTurner-qx9xb]

The 1/2 life of MB is 12-14 hours (not 5). Hope that helps.

[@anguslean4058]

It means you still have MB in your system Some people take MB then there urine turns either blue or green or blue green They wait until there urine is back to its normal color before taking another dose Low doses like the one you are taking seems to have very positive results Higher doses are being used for people who a specific problem Like Lyme Disease I think the lowest dose with positive results is better in general

[@simonleland2873]

There is zero correlation between half life and when you pee it out.

[@frankv8858]

There are some wild comments here. Not all liquids are the same concentration. A bottle of 1000 PPM is not the same as 5000 PPM. You cannot just arbitrarily tell someone how many drops to take. If you start from a powder, also that powder has a concentration. Be careful how you calculate.

[@winstonbrown1516]

The standard of MBlue people buy is 1%.

[@Sandy-fg2lu]

I tried the methylene blue for 3 days, 1 drop and then 2 drops once a day. One day I only put it on my face in a cream. Every time, I'm completely flattened the next day. Very low mood. After 48 hours I'm good. I'm wondering if this is detox and need to lower dose or I shouldn't take it. There is that G6PD contraindication thing that is rare. I really want to take it, I feel it's helping but I can't crash like that each time. Anyone else take it? I'm a senior.

[@alholds]

Sounds like a herxing reaction

[@MartaBotta]

My doctor said it can cause a herx reaction. Lower your dose, stay on 1 drop for 2 weeks before increasing.

[@Aangel452]

I heard in another study and dose recomendation that the day after the first dose you will feel lathargic but that as you continue that all changes to more energy!

[@rhonda3707]

I'd be interested to hear how this came out for you. I had the same reaction. My KST doc checked me and found my body is adverse to MB and asked me to never take it again. For my husband it came out as highly adventageous.

[@Aangel452]

Stay on only one drop per day. All the mefical trial have shown that less works better and they always recommend only one drop.

[@prdeacon974]

77 kilograms takes how many drops?

[@kerriwood6500]

What does it mean if my urine doesn’t change color when I take it?

[@094340]

You probably aren't taking enough.

[@wendymccleary1465]

I'll add to the previous comment.. you aren't taking enough to make your urine turn green or blue. That being said, it could still be the correct amount for you.

[@yourenough3]

It took about 4 days of using 20 drops in am and 10 drops in the evening before my urine was blue or blueish green.

[@supermusclemaniac1]

For a 250lbs male taking MB taking .5 mg per kg of body weight is 56 drops per day? Can someone who knows confirm if this is correct?

[@fluffychenille]

Yikes! That's a lot in my opinion. I am 190 and I take 7 drops in a 1%solution

[@SupremeODMG]

I think i will try some, my lymph% is low and neutrophil % is high making my NLR a 6...i hope this can khelp memkill off whatever virus is active (i believe this is my 4th covid infection)

[@Lauren-vd4qe]

did u get the pointy; if so, thats very bad news.

[@PrincessAloeVera]

with food or on empty? am or pm? thank you.

[@TruthBFree]

I have read that MB is best taken after a meal.

[@PrincessAloeVera]

@@TruthBFree thanks.. I'm still learning more about this.

[@Aetherfield]

Can it be taken in the morning with coffee? What other foods or supplements may interfere with it’s absorption?

[@yogimaster1]

Do NOT use Methylene Blue if you're using any type of antidepressant or anti-anxiety medication or anything that acts like or is an SSRI or MAOI. This includes SSRI’s and MAOI’s such as citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, zimelidine, bupropion, buspirone, clomipramine, mirtazapine and venlafaxine. Also, avoid taking CoQ10 with methylene blue.

[@wildpetals]

@@yogimaster1 why no coq10?

[@yogimaster1]

@@wildpetals I don't know why but I read that on the nootropics expert's website.

[@josephinemarino389]

​@@yogimaster1 buprppion isn't SSRI. I'm scared to try this product

[@yogimaster1]

@@josephinemarino389 It's an antidepressant. I read that any type of antidepressant or anti-anxiety or anything that acts like (or is) an SSRI or MAOI should not be taken with Methylene Blue. I believe Methylene Blue in the proper dose by itself is safe for most nearly everyone but mixing drugs can be dangerous. If you're taking any kind of medications I would talk to my doctor about trying Methylene Blue.

[@drdovfrommcruk8489]

How many mg of meth blue is ther in 1 ml of a 1% solution?

[@winstonbrown1516]

20 drops = 1ml. 1ml = 10mg.

[@IrishMags100]

How long would you need to be off antidepressant before starting MB

[@DANTHETUBEMAN]

always take low dose psilocybin mushrooms for depression. and you have to work through life problems they can't be cover up, 😊

[@richardmalone3172]

Most SSRI medications have a washout period of up to two weeks. Fine after that. Start low dose and gradually move to your target dose.

[@DANTHETUBEMAN]

anti depression??? maybe you should be depressed and work on what's bothering you? 😆 honestly, get psilocybin mushrooms and say goodbye to depression. 😆

[@AH-gk6qs]

How many mgs of MB are in one drop of a 1% solution of MB?

[@simonleland2873]

0.5 mg per drop of 1% solution.

[@AH-gk6qs]

@@simonleland2873 Thanks!