NSAIDs | Non-Steroidal Anti-Inflammatory Drugs

In this video, Dr Mike explains how NSAIDs work! He discusses the role of prostaglandins in the body and how different NSAIDs like aspirin, ibuprofen, diclofenac, naproxen, and coxibs target enzymes called COX-1 and COX-2 to try and stop inflammation, pain, and fever.
He also outlines the relevant side effects for each type of NSAID.

[@JenniferLee-26]

Your videos are the only ones I actually enjoy watching to study. Actually, it’s less about studying and more about stimulating curiosity, appreciating how cool the human body works, and that great feeling you get when you finally understand something that has gone over your head before. You’re the best, Dr. Mike!

[@reviewpharmacy]

You are master in explaining the concepts.

[@Joannapl111]

i study pharmacy n i watch these videos everyday for three years now! thank you is not enough!!!

[@dabeezkneez8716]

This was probably the best explained and most useful information I have watched in the past month on youtube. Thank you🙏🏾.

[@Javi_G21]

I'm not going to lie, I'm not too big a fan of how the new videos speed up when you write. One of the main reasons I love your videos is because the buffer time of explanation and writing, helps me process. Now that it is sped up, my mind doesn't have, what used to be, a beneficial processing time. Just thought I'd throw this out there incase I'm not the only one.

[@DrMattDrMike]

Good to know!

[@gina4168]

I agree. Great video otherwise.

[@tammyomerza8043]

Another great Video Dr. Mike thanks for all you do!

[@reseking6119]

Dr Mike!! You’re awesome! Thanks for breaking it down and making it easy to understand. I appreciate you and your team!

[@Seaweed-oi5pl]

Your channel carried me during nursing pre reqs and now I'm back as a nursing student, thank you!

[@sky_laithalhaidary4238]

Thanx for everything you share🫶🏻

[@jaimeelliott6154]

I dont know what i'd do without you! You're a legend . thank you. when im a rich osteopath ill send you some well deserved dollarrrr x

[@reneedavenport5817]

Love you sooo much, Dr. Mike. This information is so helpful…. Like everything else you selflessly share. ❤❤❤😊

[@angelaflynn8747]

Love your videos, please please can you do something on "how local anaesthetic works". I hate having to look for other sources, as they never compare.

[@alisaalspach7737]

Love your explanations. Thank you!

[@Momandmeherbal]

Why worries when there is Dr.Mike ...Hats off sir😊

[@crystalrubbie9383]

where have you beeen all my life life life !!!!!! this was amazing Dr

[@mattbhmb98]

Amazing content, you sir explain things way better than most lectors I have!

[@brotherweitalk]

Great explanation! Super easy to understand even as someone without any knowledge.

[@leyllafarooq6463]

Your videos are really helpful for pharmacy students. For future videos would you also do videos on other drug classes and their moa. Thank you for your videos!

[@Ouki99]

100% agree on both points ❤

[@jamalmusic6034]

thank you doctor for the best explanation... subscriber from malaysia 🇲🇾

[@pz3j]

First class job Doc. Thank you.

[@DrMattDrMike]

Glad you enjoyed it!

[@Hady_gg]

Absolutely amazing

[@superstar50281]

Love all your vids. Are you able to please do one on the side effects of corticosteroids?

[@abdirahmanfarahjimcale3611]

Thanks Dr Mike

[@awandemaxmpofu3763]

Many thanks for your informative videos.

[@user-xn2qh7fl7q]

Very helpful information. Thanks Dr

[@dilipaweeratunga]

thank you dr huge Sri Lankan fan here!

[@teri2466]

Wait, wait!!! What about acetaminophen? Nevermind. From wiki ☺️ Paracetamol (acetaminophen) is also a COX-2 inhibitor almost exclusively within the brain, and only minimally in the rest of the body although its not considered an NSAID since it has only minor anti-inflammatory activity.[3][4

[@teri2466]

Thanks for explaining NSAIDs, doc ❤️

[@user-uk7uq4um3x]

you deserve more likes

[@yilbertlipinyuen7503]

Very informative video. Thanks very much

[@asifiqbal9994]

very helpful for me thank you so much.

[@meetchaudhary1945]

great explanation thank so much ....!

[@MunyaradziMtangadura-mn2cm]

Very educative

[@hayaalqadomi9493]

Thanx you are great. ما شاء الله ✨

[@VishalYADAV-we4vu]

Thanks 🙏🏻 from India

[@rishiraj2548]

Thanks

[@doridenis1204]

I wish you were my uni teacher.Please upload more about pharmocology❤

[@DHILLONSAAB]

Thanks love from India ❤

[@SarkisKlinik]

What is the longest duration of time and dosage that we can give acetaminophen and NSAIDS for elderly with chronic pain ?

[@vaishnavikaremore9305]

Loved it ❤

[@gladysjebichii2132]

I wish i could like a thousand times yoi are very educative

[@Arrow-999]

Hello sir, I am an engineer by profession and have nothing to do with medical science. But currently I am on a journey to get fit and muscular, and your bio video really helped me to understand the human body. I have a question to ask if you can please answer. When and why my body decides to use which energy source to fulfill the calorie needs. In other words when my body decides to burn fat , when to burn carb and when to burn protein for daily calorie requirements. And If I am in a calorie deficit, what will my body burn first and how much

[@frankjesse4304]

Great job 👏

[@DrMattDrMike]

Thank you! 😃

[@antoniocavalli5474]

Crazy good video

[@brotherweitalk]

Good content!

[@canada959]

Great video.

[@DrMattDrMike]

Thanks!

[@RZAYAHD]

amazing

[@fuadzinab4039]

OMG you are great❤

[@R00ba]

Omg You Are The Best Thank Yaaaaaaaaaaaaaaa

[@user-ji3vt9mh5t]

Nice content and first comment ☺️

[@ashlynningard595]

I was under the impression COX-2 works to dilate renal vasculature. Please clarify.

[@KloiKoch]

I found that Meloxicam is classified as an COX-2 Inhibitor. Since Coxibs were banned, I assume that Meloxicam does contain some amounts of COX-1 Inhibitor as well?

[@oona6161]

I am confused, why coxib is the one needed to have a dortor's prescription before you buy it, while the other NSAID has no need prescription, where as you said first few names of NSAID mention are dangerous on other function of the body. Sorry for my english. I Hope this could be answer. Why?

[@lizbethportillo2113]

would someone mind explaining why COX-2 has platelet inhibition i thought when u get injured like a cut platelets are important to prevent blood from leaving your body. Did i misunderstand?

[@m.a6894]

Pls can u upload a video on the Krebs (TCA) cycle plssssssssssssssssssss😩😩😩💕

[@aprilpoppytui]

pecs are very distracting dr mike. had to keep going back to re watch certain parts as i was getting quite distracted

[@badee8953]

*wonderful name huh*

[@siirzeren]

Can you please add subtitles in videos🥰

[@DrMattDrMike]

Click the CC button 😊

[@tahibsalam7175]

Hello sir I am from India. Iam a MSc Renal Science and Dialysis Technology student.... And i need your help .

[@bobwen3809]

Hi, I wish you could do better on your sliding filamet video. It is so extremely frustrating to see the same "explanation" repeated again and again whem it obviously doesn't work at all. Your video explains why the myosin and the actin filaments slide together and hold ONE TIME, resulting in a minimal contracrion of the muscle. It does however NOT explain why this process could happen repeatedly, resulting in a further shortening of the muscle. Once the myosin and actin detach, the filaments are pulled to their original positions since there is nothing mentioned that would hold them in place.

[@Eric-sq4hd]

what your thoughts on using NSAIDs to treat a muscle strain (such as a lumbar sacral sprain) - because I've read different research articles on this, some saying inflation is useful for tissue repair, while others saying reducing inflammation is better overall for healing

[@bigp3441]

I’m allergic to them 😢

[@user-ox6nc6ly7f]

but who want to block cox-2? block healing...

[@BattleSymphony349]

All these cause of inflammation

[@christalbott450]

Hi. Life and everything in in is created by God himself. The son of him, Jesus, forgave all of all things. Breathe in air.

[@dhillonamarsingh5033]

Superb explanation 👌

[@gabesalgado789]

I have no idea what you're talking about.

[@robertdaymouse3784]

Dear KZbin, please offer a way to filter Australians out of my search results. I am willing to pay your monthly membership fee if it is offered with the membership.

[@bobjohn1555]

Thank for this incredibly necessary and profound comment.

[@DrMattDrMike]

I didn’t think my accent was that bad 😔

[@cutteybee]

Sickening is what you’re.

[@kimberlybrewer8547]

​@DrMattDrMike, certainly not! From the US here. Just found your channel today as I am desperately searching for something, anything to help with unbareable 😢pain and nerve pain in my that started from a bad dental injury in my early 20s. I since lost my teeth due to severe to me and my elderly parents by an extremely narrarsist sister. On gabapentin, hydrocode, and gabapenentin. Not helping. If there was a way to burn my nerve endings, I would.

[@kimberlybrewer8547]

​@DrMattDrMike, certainly not! From the US here. Just found your channel today as I am desperately searching for something, anything to help with unbareable 😢pain and nerve pain in my that started from a bad dental injury in my early 20s. I since lost my teeth due to severe to me and my elderly parents by an extremely narrarsist sister. On gabapentin, hydrocode, and gabapenentin. Not helping. If there was a way to burn my nerve endings, I would.

[@iflahmalik5596]

You're so underated 🤍.... Grateful to you❤️