Side Effects of NSAIDs | Pharmacology

NSAIDs (Aspirin, Ibuprofen, Celecoxib, Diclofenac)
All of us have taken at least one kind of non-steroidal anti-inflammatory drug (NSAID). We take them when we experience pain, inflammation, or fever. However, the action of these drugs are more widespread and, even though they are safe within their therapeutic range, their side effects should be noted!
The most common side-effects from NSAIDs include:
- Gastrointestinal (GI) bleeding
- Platelet (clotting) dysfunction
- Renal injury
- Hepatotoxicity
Let's take a look at how these drugs work and how these side effects occur!
Listen to our podcast for more info: podcasts.apple.com/au/podcast...

[@GeorgeAscue]

As a vet student it's so important to remember always everything you said in your video. Thank you

[@howtomedicate]

Important video! I always preach this to my students.

[@owenalden742]

I take a steroid inhaler for my lungs occasionally, the bottle said don’t take if take steroids. Should I take aleve pm?

[@PhillipandIsraelgaming]

Where have you been all my life? This was a great lecture. Thank you.

[@xinliu4852]

Great video! Would like to watch more pharmacology lectures like this one!

[@jeremiahavwerosuoghene5990]

Great video, thanks Dr Mike you just made this pretty easy. Thanks alot.

[@cricket4759]

Re. Setting the hypothalamus higher Higher and HIGHER - really excellent detail on NSAIDs MOA - thank you

[@scorp130n]

You are outstanding! Keep posting!

[@wojoud1344]

Best channel EVER ❤️

[@kathysteele5052]

Great presentation for explanation. Much appreciated. Thnx

[@peaketraining8812]

Great info Dr Mike

[@laurieb9053]

These should be taken off the market! Read ask-a-patient reviews. Could not walk for 2 days from the SEVERE dizziness, suicidal thoughts, stomachaches from hell, tinnitus...it is poison.

[@Hartleymolly]

I’m here after taking an anti inflammatory for my back and now feel like i’m dying a slow death, I have been up the entire night, it hurts so bad, it’s so incredibly uncomfortable.

[@markharnet2660]

Brilliant presentation!

[@danukapriyanath3252]

Wow great explanation ,brilliant teacher 👍👍

[@ohno9720]

Hey great summary!!!

[@shawnmager7860]

is it safe to use voltaren topical gel

[@Achhantei]

Please do one on aspirin and NSAID allergies!

[@mikeinpcola5543]

So for a person with low platelets (75), what would an NSAID do to them? Does it lower platelets and cause bleeding in general? Would it cause passing blood in stool?

[@SeanKobiSandoval]

I am having IBS from ibuprofen. How should I heal myself?

[@Smiesznotka00201]

Hi can you link any reaserch proving that celecoxib doesnt increase risk of blood clots? This is first time I hear about this so I'm really curious

[@SarkisKlinik]

What is the longest duration of time and dosage that we can give acetaminophen and NSAIDS for elderly with chronic pain ?

[@lapharmacie98]

Literally had a lecture on NSAIDs in my Pharma 2 class haha

[@E_tiBEAMERBOY]

Any treatments for a slight discoloration in urine from the Diclofenac ?

[@nifigriffin]

THANK YOU!!!!

[@3lla387]

Thank you so much

[@garyhaber6957]

Great explanation.... awesome info.... Do u have one on Paracetamol bro?

[@laurencejones8977]

Ibuprofen and Naproxen Sodium can cause a bleeding stomach ulcer. A bleeding stomach ulcer can become a perforated ulcer, which you can die from. I know this for a fact, from personal experience. In 1985, I had a perforated stomach ulcer that required emergency surgery to repair. A couple of weeks later I developed an abscess of infection beneath my diaphragm that required a second surgery and almost killed me. I was in the hospital for almost a month recovering. Just because a medication is available over the counter does not mean that you can take as much as you want, for as long as you want, with no risks. Taking too much aspirin can also cause a stomach bleed.

[@gschaaf713]

do NSAIDs have any effect on nitric oxide production?

[@BigstickNick]

Wheres the video, on how to improve the effects from NSAID?

[@bennym1326]

I accidentally took a large dose of NSAIDs and they have completely destroyed my stomach... will my stomach ever heal?

[@ASADKHAN-xr1rz]

Can diclofenac potassium be used in hypertensive patients ???

[@jadeheaton2010]

Wondering how I can reference this whole video in my essay... the most useful info I have seen out of 30 papers/ journals 🤔

[@johndoles3713]

Wow great channell

[@kimtatum-moyer4232]

Would love to see you all cover antiretroviral meds……..please?

[@Mindbreaker89x]

If someone is given meloxicam 15mg instantly without even trying a lower dosage first, could it cause higher blood pressure? And can it cause feelings like a pressured feeling in head and hands etc? This medication was also in combination with thioctic acid? Can these two medications even be safely put together? The thioctic acid is used to treat neuropathic pains and i feel it may interfere with each other. Also can the increased blood pressure caused from Meloxicam be in the body for longer than 24 hours and causing a increased blood pressure?

[@SimranKaur-fc4hn]

Do NSAIDS show side effects after 2 months????? please do tell me anyone who is acknowlgedd by this.

[@theresageiger584]

GREAT IM JUST GOING TO DIE

[@josephfriday2661]

QUESTION: So, are you taking NSAIDs with food to decrease absorption or because the drug, while in the stomach, causes direct irritation? If the former, you could take the first dose and get better results.

[@trafficjon400]

Side effects is a easy way of admiting bodily damage that can last a life time of torture is a fact by many who are not passive .

[@Nooor03]

Hi.My daughter is eight years old she started to use anti inflammation drugs two days ago but she cannot sleep at night because she’s coughing all the night .is it normal ?or bad? can you please let me know thank you?

[@melissaseago536]

She needs to cough to keep from getting pneumonia. Staying well hydrated will make mucus less thick and easier to cough up.

[@stackedpennies4377]

Whoa whoa whoa. I’m too much of a dummy to keep up. I have slight asthma, I have a NSAID allergy, and my stomach is upset a lot. These are somehow related?

[@abdulbari-_-]

Does it get you high ?

[@heinhtet8956]

why is your volume so low! great content but please fix the mic. thanks.

[@LIZZYYYYYYYYYYYYY]

I thought aspirin was COX non-selective?

[@cricket4759]

Yep it is

[@anindividual9225]

Ok, now explain it to me like 5.

[@kaladharyadhav7697]

Hi

[@sagrammyfour]

...

[@ajayfacts81]

Take turneric, garlic, ginger to cure inflammation.

[@thechurrosofficial]

Pls help me ...i took diclofenac and malatose for 8 days i started having rash and my feet is swollen..doctor prescribed me to immediately stop the medicine ..but i am really worried ... can my kidneys get permanently damage just for taking the medicine for 8 days...pls reply me .

[@mohdshariqansari6750]

How are you now dear?

[@hugh2hoob668]

It gives me panic attacks

[@texasscifi3431]

I need it for pain but yes I am experiencing panic

[@sunilundercover]

​@@texasscifi3431to me also

[@aadityajha123]

I had neproxin and ibuprofen 2 days back because I was having serious back pain. Now I'm having pain on my uppar abdominal right area from last 2 days. Please help me

[@ellenlee1]

WHAT WAS IT? DID YOU GET WELL. KIDNEY STONES.

[@aadityajha123]

@@ellenlee1 no, that was a side effect of the pain killer I believe.....I'm fine now....Thanks for replying after 3 months... : )

[@jas6274]

Hi i m too having stomach pain bcoz of pain killer meds, can you tell me in how many days yours got treated?

[@aadityajha123]

@@jas6274I'll suggest you to wait and don't take any medicines further....it took about 1 month for me to get that pain and strange sensation in my stomach out. Eat light and avoid foods that are hard to digest

[@jas6274]

@@aadityajha123 ok thanks

[@theresageiger584]

Nsaids killed me

[@jamesvw769]

Im very sorry. See you in the after world.

[@galacticwarrior4089]

Ok that makes sense

[@bornwin-sx9oz]

I know exactly what you mean!

[@bryanstellfox8521]

Hehe he said Cox 🙄