Solving the "Lack" of Anti-aging Discovery & Ranking Current Interventions | 42 - Mark McCormick

[@oanabaghi]

The reason why I watch these type of podcasts is because I have death anxiety and I really don't know how to stop thinking of that. Can you make a video about this subject?

[@mnkwazi]

@oanabaghi it can be hard to accept.

[@Mojo_DK]

I study Biotechnology in Heidelberg and am doing an internship in Japan rn where I am working on GCN1 and autophagy. So this interview was very interesting and helpful. You are doing a great job!

[@workingTchr]

Really nice to hear someone researching aging who wants to double it and _then_ say, ok now we really have something and we're not just getting a few years here or there. Although, after you cross 70, every little extra bit is welcome!

[@susymay7831]

I really like the numbers game with interventions and people!!! ❤

[@tinox12]

thanks for you hard work :) we really need it

[@timskolnik3819]

Finally, some positivity from Dr. K on improving lifespan!

[@zombi3lif3]

What an awesome conversation 🔥

[@adjusted-bunny]

I love McCormick. The best spices ever!

[@smedleyjefferson1450]

Against sarcopenia, you could do cyclical protein restriction: on some days restrict, and others do not.

[@diamond_s]

Hearing about targetting trna synthetases found this interesting paper "A Human tRNA Synthetase is a Potent PARP1-activating. Effector Target for Resveratrol"

[@hristosstrihas4010]

I find senolytic drugs/phytochemicals extremely interesting. It would be interesting if more attention was paid to this approach. I would also like to point out that probably the action of substances that have an effect on longevity and health is influenced by context. For example, leucine (and BCAA I guess) has a completely opposite effect when administered while insulin levels are low/high. My guess is that this is a general fact.

[@tonygorman9462]

Maybe the issue is that the geneticists are only looking under the DNA lamp and that is not where we will find anti-aging interventions. Maybe they should be also be interested in the work of people like Alfonso Martinez Arias who is leading developmental biologist argues that cells, not DNA, hold the key to understanding history, present, and future of life.

[@axellieb]

May I respectfully suggest to Dr. Kaeberlein that he please make up his mind as to whether he is the interviewer or the interviewee? The frequent interruptions of the interviewee's flow of speech, and the constant directing and "supplementing" of his comments are incredibly irritating. It also makes you much harder to like. Which, considering that you're trying to educate and influence the public discourse here, is quite important.

[@jds02153]

I like this style. It's called a conversation. Try having one.

[@axellieb]

@@jds02153 kzbin.info/www/bejne/an_UdJeNmJ5niNk

[@scotlandtheinsane3359]

Yeah, it's like looking in on a conversation between 2 scientist colleagues.

[@janineclemons746]

I wonder if this could be used to suppress the replication of COVID/COVID spike protein.

[@PrometheusLux]

I would love to hear your opinion on HBOT

[@camarosspr]

Cause We don't have the knowledge required, still, now we're at most 30% knowledege, we need a passing grade over 70 w computers, AI, future real AI, Science, we'll move magnitudes better on ever shorter times Maybe in 30 years, hope I last till.

[@scotlandtheinsane3359]

Because of AI I think you can't even put a number on it quite. And there should things on the way to get you there now. In the meantime, it's the gym, the kitchen, the sun, relationships, caloric restriction etc..

[@TitusEddiePlayz]

onwards to 10K

[@ats89117]

How do you know if worms are happy?

[@askingwhy123]

Here's a short description! "Behavioral and developmental assays of C. elegans using microfluidic technology"

[@camarosspr]

We need significant anti-aging Like reaching 120 w great health muscle mass, brain and organs not degrading significantly So Most are from 5 to maybe 4.85.

[@camarosspr]

Were not getting better results even though we're have magnitudes more knowledge today, we're still At most 30% knowledge for all Just read medical drug literature We know it works, we don't know why.

[@pine5088]

Yoong Walter White

[@bostaurus1]

Maybe let the guest speak freely when ranking

[@morgancambara2792]

Taurine🔥glycine🔥

[@russianprincess3673]

Fake News there is no cure for aging ♥️♥️♥️ at this point in history Yuliya

[@Nelis1324]

They are not claiming there is a cure ..

[@adjusted-bunny]

Allspice works wonders for balding men according to a study

[@Krunch2020]

Ha ha ha. Once one attracts a mate there’s no need for the plumage.

[@temp7350]

What a horrible interview, why did you rush and keep cutting off the guest? If you wanted to act smug and complacent, then don't do a guest podcast.

[@rusne167]

Hi there, Matt! I have been trying to contact you through your email address regarding some business offer... It seems like the email address is not valid - I would appreciate it if you could share the correct email address with me. Your videos are just great!