The HUGE Brain Benefits of Fasting: Dom D’Agostino & Thomas DeLauer

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I had the privilege of sitting down with Dr. Dom D'Agostino, neuroscientist, professor of molecular pharmacology & physiology, and one of the world's leading ketone researchers, to discuss how fasting (and keto) change the neuropharmacology of your brain!
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The HUGE Brain Benefits of Fasting: Dom D’Agostino & Thomas DeLauer
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Timestamps ⏱
0:00 - Intro
0:10 - Joovv's Red Light Therapy Devices
0:32 - Do Fasting & Keto Need to be Combined?
4:59 - Why Dom Likes Fasting
5:54 - Why You Shouldn’t Fast Every Day
7:51 - Why Fasting Increases Focus & Calmness
12:03 - The Benefits of Magnesium
17:20 - Zinc & Brain Health
18:13 - Fasting & Keto Change the Neuropharmacology of Your Brain
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Please watch: "Costco Diabetes Haul | Best Foods for Diabetics & Insulin Resistance @ Costco"
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[@thomassimms3975]

Went to school with Dom used to call him the Dominator !! I remember lifting weights with him in his garage. The guy was very ambitious about health so makes so much sense why he has a huge role in helping people today.

[@billytheweasel]

Thanks for sharing that. He's helped me online for years... but I'm a keto LMHR and need to be cautious until the high LDL on keto is determined safe.

[@Innerknosis]

Love this! Need more interview/discussions with Dr. Dom D’Agostino. These are my favorite kind of discussions.

[@SuperDoggy99]

I would love to hear these guys talk about ADHD and the role diet plays.

[@venkataponnaganti]

Two stalwarts in the field. What a pleasure to listen to them and learn about If. Thanks.

[@samanthabrooks4603]

I’m really enjoying your discussions with other experts

[@5MinuteBody]

I keep watching Dr Berg, Thomas Delauer and Dr Ken Berry. They should all collab to save the world - the quintessential Keto Kings❤️ I am mentally sharper, quicker, and more productive when fasting 😁

[@reneecampos1261]

And don’t forget Dr. Mindy Pelz!

[@thors1fan140]

Also don’t forget Jason Fung.👌

[@juneweeks3539]

@@thors1fan140 Yes he was the first fasting guy we followed years ago.

[@knp4356]

Pharma will come after them and hurt them for spreading this information if they unite. Best thing you can do is share these videos with family and loved ones. Pharmaceutical industry is deeply connected with government and they will do anything to keep America and people unhealthy. They want to sell you insulin and other meds. They make more profits. Pharma have spread and scared people into thinking fasting is unhealthy and that it’s dangerous. Lol

[@laurenmcdonald7086]

More of him please. So insightful and motivating to stay in ketosis.

[@jond.6816]

Fantastic video Thomas! The research continues to fascinate me regarding keto and intermittent fasting.

[@cherylpaniccia4920]

Great combo. Two experts. Love this video.

[@salvenice09]

Awesome! Dr. D’agostino is a leading researcher on the effects and benefits of the Keto diet👍

[@Siameezkattwo]

A very helpful vid. Thank you Thomas!

[@billytheweasel]

I've been following Dom since about 2013. His cancer work is huge.

[@texasgrannieof2]

Love this content!!!

[@richardtoomey8628]

Great stuff. Learned alot

[@jeffreyharrison4045]

Fantastic collaboration!

[@firmbeliever3847]

love these interviews Thomas, youre the best interviewer.

[@marlenes.1738]

Thanks Thomas for another great video!

[@erichanson5628]

Thanks Dom and Thomas!

[@berk7437]

Wow. Incredibly informative and entertaining!

[@marzs794]

Dom looks so good for his age. I would have guessed 35 maybe 37 but not late 40's earlier 50's. I hope to age that well lol

[@dennissvistun922]

Thomas, could you do another video about cyclic keto and what carbs to eat when doing a carb cycle? Maybe even a grocery haul from Aldi, Walmart, Costco, etc. for healthier carb options when someone is eating carbs. Thanks

[@bettyhall8567]

Yes I agree 👍

[@milesrost6674]

AGreed

[@clerede6382]

Speaking from personal experience I do cyclical carnivore diet, so when I increase carbs I usually drink low-fat milk , buttermilk or kefir , also I increase my protein and decrease fat intake to 2:1 ratio.

[@milesrost6674]

@@clerede6382 Thanks for your insight. Do you mean you rotate a carnivore diet with a normal-ish diet just by increasing carb intake a little and more protein less fats?... Or you do keto and alternate carnivore with carb increase and fat decrease?... Thanks

[@jacobpope11]

YES TO THIS!!

[@andrewlittlefield3425]

Nice information

[@MrKeltybroadstone]

Jeezus, Dom is an absolute beast.

[@MoCapWoman]

Love this clip! Also loved Dom's t-shirt. I live in Alaska!

[@user-xc9sv5hk2d]

❤️❤️❤️❤️ great info❤️❤️❤️❤️

[@domleigh5032]

Thank you so much :8)

[@tonipieleanu]

Too short 😩 Really cool for you to interview Dom. He is really knowledgeable in this field

[@stefanweilhartner4415]

instead of salt, i use sodium bicarbonate. also good before going to bed after some alcohol consumption. and after getting up. for fasting, i highly recommend taking 1 teaspoon of inulin 3 times a day!

[@gilbertwever5185]

Thank you for all your advice. I have lost over30 pounds since Thanksgiving, dropped blood sugar from 155 to 9. Combined 2MAD with acv tea at night and whole lemon and blueberry drink in morning. Keto has allowedmeto change the way I look at food

[@torgoron9695]

How do you make acv tea?

[@southerncalifornia3155]

Do a video on post workout anxiety, could you?...I always get that..

[@dinkyflix]

Please fix Thomas' mic level. He's so low compared to Dom. Simple level adjustment would do the trick.

[@AceKinG2024]

The legendary dominic !

[@barkobunga2276]

The focus and positive mood that comes with fasting works wonders, which is why fasting is emphasized so much in Orthodox Christianity and religions with monastisism. No surprise that so many great inspired minds came from monasteries with ascetic lifestyles.

[@mohamedeassa]

Love this

[@hazor777]

My longest is 4 days - and I will say , if you try to start and fail, and eat..... pay it no mind, and continue on an eating schedule until you're ready to try again. It's easier if you've already acclimated yourself to intermitten fasting (me: 1 meal a day). There's no shame in breaking a fast before your goal time. I've found w/me it's about momentum : if you can get past that first 36 hrs, it's a little easier to lock in one more day. Then again my limit , so far , is 4 days. It's almost addicting , in terms of how much better you feel: your eyes feel much more clear, thinking, more energy etc... Our bodies are an amazing, amazing physical and spiritual creation. There's a reason (actually many) Jesus said :"WHEN you fast ......."

[@abbykickass3210]

I've just finished a 20 hour fast so this video has just made me feel even happier 😊

[@clerede6382]

I'm currently doing my 72 hour fast

[@MrBigdjg]

@z Vezzio z Organ removal? Like you'll poop out a kidney?

[@davidzaharik5408]

Thanks Dom, you helped save my life after poisoning!

[@Shockstar76]

I have been watching your channel and also several others regarding nutrition. I am leaning more towards carnivore diet and even though I don't see you promoting it and seem to prefer a more varied diet I'd be curious of your thoughts on it?

[@mariaorsic9763]

Bottom line: as both of you keep pointing out, there are SO many reciprocal pathways, SPECIFIC to the person, on ANY given day, that the “reality” of designing therapy for a patient is NEVER going to be driven by intellectual approach, including keto/glucose meters. Instead, patients, clients, health devotees, should be TRAINED to be “increasingly sensitive” to ALL of these physiological states, ie. ketosis , high glucose, etc. ONLY then can the individual manipulate the variables to desired ends. In short, people generally fail when applying these concepts because they can’t even differentiate between the “experience” of an insulin high versus ketosis versus the lowered metabolic state of a 2 day fast!

[@marvin22blu]

I can tell from experience brain boost during fasting is NO JOKE.

[@zacharyswain7034]

Does the calming/neurotransmission of the brain changes during fasting last after the fast even if someone doesn’t eat a Keto diet?

[@gabcq3300]

Greg Sweetie (doucette = sweetie in French) ought to watch this! It’s not just “calories IN, calories OUT!” Insulin matters!

[@Dani-jo9yr]

It is my lifestyle forever guys 👍💪😅

[@kallesand6087]

It would be nice to hear what other important "supplements" or things in our food we should not be deficient in except for Zinc and Magnesium. I heard that Vitamin D and Vitamin K is very important, but what is your take on it Thomas DeLauer? I'm trying to loose weight mostly.

[@Lenzer50]

Its not really a calorie deficit because you’re feeding off of your own fat which is still a calorie.

[@bryanbair6508]

Great content/ discussion! Especially enjoyed supplementation combined with intermittent fasting. Been on strict keto for 12 months, lift 3-4 days per week, lost 45lbs, now 6’3” 210lbs., supplement magnesium/boron/q10/saw palmetto/protein, 17/7 fast 3-4 times per week. Initially lost size/inches everywhere. Now muscular volume/ inches has increased. Question: I have weighed 210 now going on 4 months. Body composition has changed some (putting on muscle), however can’t seem to loose final mid section/ handles (abs are showing, but not completely). Feel like I’m stalling. Any suggestions on loosing this final amount of fat?

[@saintjulien6126]

Change the fast regimen. Add some 24h per week or 72h per month...you'll see the difference. Good luck.

[@musichris777]

Thomas, you came to my office and I didn't know about this?!?!? 😂

[@samaus764]

How much zinc do you recommend to take

[@gabe6498]

Dr Dom: proud Jersey boy and Rutgers man!

[@Paula-po9kx]

Thank you gentlemen. I would like to hear more about keto, fasting for controlling seizures, I have a son that had had seizures for years he refuses to take drugs to control them.

[@Soulcoaxing]

Is he on a high animal fat diet? Fat is needed for the myelin sheath, which protects nerve fibres.

[@Paula-po9kx]

@@Soulcoaxing no, he eats the all American crappy diet. He doesn’t have them very often, being really tired, lack of sleep will bring one on.

[@leeannmccoy6684]

RED LIGHT THERAPY GAVE ME HEADACHES!

[@vladig7006]

Can you still get the benifits even if someone is on psych meds???

[@U.S._ARMYGWVDSS]

🙏🏼

[@dreaminginnoother]

Holy crap, Dom is almost 50? He looks amazing, especially physique wise. Is he pro TRT?

[@LelandYarnell]

He has stated many times he would not be opposed to taking it later in life if his numbers and performance really starts to drop, but once you start you are on it for life. Thomas has stated the same.

[@dreaminginnoother]

@@LelandYarnell I think that's a reasonable approach to it. I would agree with that.

[@bionergysystem]

Thanks for the depth in here guys. To go a bit deeper on trace minerals, I spent nearly 8 years with the world leader in this space within animal nutrition and peer reviewed published research and meta analyses. The company have the greatest in depth knowledge on how these trace minerals interact and are absorbed, which led them down the path over 50 years ago with a unique and patented complex action to take advantage of the amino acid pathway to gain entry for these essential trace minerals like Zinc as opposed to the highly antagonised inorganic standard mineral pathway for absorption in the stomach. The company has also been involved in human nutrition for some time and gave some very interesting published papers. They released mend+defend range for humans. Do your own research, it’s there for all to review. I personally recommend these complexes to my colleagues and friends due to my knowledge in this industry and based purely on the science that surrounds them. There are no other trace minerals with the same capacity that I am aware of.

[@acidclarity_]

I'm a small human and omad everyday is easy and feels amazing. Maybe because I'm small

[@jollyrogers99999]

Good interview but far too many ads !

[@deepakgoldwyn7852]

40 hours water fasting once a week. And on other days 16:8 intermittent fasting(two meals a day) I see great results, but is this sustainable? Will weight loss keep happening if we continue the above mentioned fasting methods or it will stop at one point? Once we reach ideal BMI should we adjust fasting schedule?

[@DashingPartyCrasher]

Thomas has said that he prefers IF on and off, and he and others I follow say to take breaks from it, just as Dom also says here. Did you see Thomas's recent video about balancing the IF days and carb days? That might clear things up for you.

[@deepakgoldwyn7852]

@@DashingPartyCrasher thank you for the reply!

[@firmbeliever3847]

@@deepakgoldwyn7852 I think once you reach your desired BMI you might switch it up to maintenance form of feeding. But like you said, we need to find what works for us and is a sustainable life style.

[@deepakgoldwyn7852]

@@firmbeliever3847 thank you

[@guibox3]

@@DashingPartyCrasher But what does 'taking a break from IF' mean? Are you eating the standard three meals a day? Snacking? How many hours between meals? How many meals? Nobody has really stated a decent protocol for what 'not doing IF' means.

[@UHaulShorts]

Day 6 a coffay fastang. Bullay buldge still thurr

[@FIGP1]

Why does red light therapy work and does infrared also work, and if so, does it work better & if not, why not?

[@johnjustice8478]

The worst part about weighted dips is them hanging off the orchestra stalls. Sure, the result is alright, but, geez, it hurtz, while your doing it!

[@maheshtanay]

Fasting increases dopamine receptors?

[@davidfindley1588]

I've been taking magnesium for some time however I experienced a calming affect after taking vit. D3/ K2 supplement. I think these work together, but don't know for sure. I do know they help a great deal in a lot of areas. Im naturally high energy high strung. So i really felt the calming effect.

[@stefanweilhartner4415]

could be a placebo effect. the vit.d in tablets does not do anything. it first needs to be converted into 25(OH) vitamin D by the liver which takes many days.

[@linneasimchah1621]

Magnesium aids in the conversion of D from inactive to active form.

[@DashingPartyCrasher]

Yes, they do work in synergy. And as you probably know, D3 is actually a hormone with lots of anti inflammatory benefits, so it makes sense that it can be calming.

[@chrissypearson5597]

Thanks Guy's! We currently are 5-6 weeks in IF/Keto-LC-NS and the Brain is taking time to adjust, we hope to get over this soon. Any chance of contacting Dom for discussion? Would love to talk with him. LoveTruth, highest path!

[@ctwolfe72]

Question: About to turn 50, experimenting with 24 hour fasts with a workout in the last 4-6 hours of the fast. What is the best way to break this fast post workout at my age? Many thanks!

[@saintjulien6126]

Always...! break your fast with protein.

[@LelandYarnell]

What Julien said. A good lean protein source then a few hours later can have a larger meal of protein and fat

[@mitzir3873]

Get ready to fast more, because food is becoming more and more scarce these days. 😏

[@debbiecicala4467]

Yay 😀

[@Journeyofamomdoc]

What is considered low carb? Under 100? Or 75?

[@DashingPartyCrasher]

I'd also like to know. I think it's different for each person based on their size and metabolism. I try to stay low carb, but for me that's still includes about 100g of organic oats daily, plus lots of veggies, nuts, healthier proteins, and the occasional chickpea pasta night. So compared to the average person I'm low carb, but I prefer to tell people I'm "slow" carb.

[@jacobpope11]

Ive been on Keto for a little over 3 months. I am just starting to cycle off for 3-4 weeks then back on. Can I just jump to intermittent fasting or do you still need to cycle off Keto so you do not become Glucose intolerant?

[@debbiecicala4467]

Yayyy 😁

[@tulio3571]

So now i should not do 16-8 everyday ?

[@ThomasDeLauerOfficial]

No, I’ve been saying this for 4-5 years. Gotta love KZbin not serving all my videos to people 🤦‍♂️

[@albrackets8446]

Hey Thomas, sorry this is off-topic, but could you do a video on eating whole lemons? That is, clean a lemon with vinegar and then put it in the blender, peel, pith, seeds, pulp, and all, and make a slush. Then when you eat it, add a teaspoon of olive oil. You have some great recipes with ACV, maybe use that and cayenne. There are supposed to be super benefits from the whole lemon, so if you have any research that would be great too.

[@GuidetteExpert]

But doesnt being in a caloric deficit on and off have the same effect as fasting on and off? 😂

[@americanmambi]

See, when your doctor looks healthy and jacked, also not pushing any pills on you, maybe you outta listen !!!

[@SuperDoggy99]

"Exacerbate" means "to make worse". It doesn't mean "to make stronger."

[@vinnypurity8819]

Imagine not understanding what your talking about , but still making videos of yourself grasping at straws... this nonsense conjecture doesnt help.

[@davidleeattorney]

First

[@Anne_Onymous]

Kids still doing that?

[@mrkoky11]

Why are you using toddler weight for single leg rdl with contralateral hold sir

[@randumb2295]

Does this guy speak English?

[@Jeremylinder7]

He's using alot of medical terminology. Biology & physiology.