Pharmacokinetics and Pharmacodynamics

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
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Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
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[@DirtyMedicine]

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[@kashafjehangirkhan7124]

How to join the channel

[@draleenavlogs498]

How to join?

[@annemarshall752]

The fee for monthly membership is not 4.99 it's showing 9.99. Is this correct?

[@MsPriyanka6]

Hi, I finished my step 1 on July 30 and got 238. I am so happy. Thanks to you atleast i got 10 or more than 10 questions correct only because of dirty medicine videos. Thank you so much 🙏🏻🙏🏻

[@TravelTherapy022]

Sounds great 👍

[@sandhya797]

Which ones do you recommend?

[@farooqahmad8044]

Great yarrrrr

[@yajayrawalquirialopezmedin5655]

Hi. How was your experience about Step1?

[@simplex6941]

You think you're smart, how much Tylenol does it take to blow up Albania. I will be waiting.

[@SG-cr2zr]

Mnemonic for drugs that follow 0 order kinetics: Zero WATT Power. Zero: 0 order kinetics W: warfarin A: alcohol T: Tolbutamide T: Theophylline Power: Phenytoin

[@user-ep5pf4hb3q]

erm, what the sigma?

[@BaoNguyen-hb9ur]

I hated this subject so much while in school. The way you’re breaking this dry material down is amazingly good Thank you!

[@User-s868]

I’ve been searching this subject for two days!! Couldn’t find something simple Expecting this to be the answer Thank you

[@videoinformer]

One unstated fact that needs to be made clear: Reaching "steady state" requires *repeated* constant doses of the drug being taken, not a mere single dose followed by a number of half-lives. Taking a drug once will result in elimination until it's all gone from the body, never reaching "steady state". Another subtopic worthy of attention is the affect of an initial *"loading dose"* (typically a double dose) on kinetics and attainment of steady state at a serum level that is still determined based on the subsequent regular dose -- *not* based on the loading dose. Naproxen is a familiar nonprescription drug that has label directions that allow for an initial *double* (loading) dose followed by the normal dose at regular intervals of 12 hours.

[@DirtyMedicine]

Yes to reach steady state there must be constant dosing, this was implied

[@OptimizeYourHealthPhD]

@@DirtyMedicine Yes it was...

[@Guidus125]

I was looking for this comment, because this was indeed not mentioned clearly in the video. Imagine a single dose getting you to steady state and that the level of steady state would depend on the size of the dose... That means if you get high once you would be high till eternity hahaha

[@StarBuilder222]

This!

[@itsgonnabeanaurfromme]

@@Guidus125 that needed to be explained? He said "you're taking the drug as prescribed", not "you took the drug". These videos are designed for medical students so it is expected people watching would have at least know these things. But it is understandable it may be hard for you if you have no medical background.

[@nambozohadija3023]

What a Wonderful summery. Thanx big, bless u

[@DrSajjadPathan]

So Clearly explained. Keep up the good work. Thank you

[@HenryRph]

This was the most instructive insightful easily understandable video on Pharmacokinetics I have ever encountered on video and in Pharmacy school!!!!

[@SpeedyMedical]

Was tryin to study yesterday, couldn't understand much , thanks for always being there!

[@vaishnavishashidhar9686]

Thank you so much!!! You’ve made it sooo clear, can’t thank you enough

[@kpulkit5627]

Ive seen a question solely testing on this same principle that the first part of the elimination graph for 1st order kinetics Is not the elimination but the redistribution itself! Amazing work as usual Dirty !!

[@givenmichael6177]

He said its distribution

[@shanthisenthilkumar3831]

Awesome presentation. Thank u

[@komaldiptianandmaisuriya4301]

Thank you so much for all your video especially biochem & pharma .you make it all easy . ❤️

[@chefinwhitecoat]

Just watched the whole thing in one min, I am getting better

[@habakkukwilsonik2740]

Wow, Exllent explain 👏👏🤝🤝

[@Mdepaivaoliveira]

Great video. Thank you very much

[@nesisamoyo6904]

wonderful stuff keep going, I now know everything about steady state and pharmacokinetics

[@darillynn]

Thank you! Can you please make a video on diuretics?

[@MuhammadAli-jd2ut]

Appreciate your work 👍.

[@adityaoruganti9307]

Soo needed this at the moment You are a savior angel 🤟

[@Timtam973]

Amazing lecture!

[@meimei2630]

thankkkkk youuu for updates! thank you

[@bronxbomma718]

This is the most banal and stale material on the boards. You somehow, found a way to make it pleasant. Kudos.

[@ambreensabah3758]

Need of the hour sir

[@xaaboopinkly]

Thanks sir!

[@carpe996]

Good lecture overall. Though probably not pertinent to USMLE questions, I would point out though that 1/2 life is NOT the time for which 1/2 the amount of drug is eliminated from the body, but the time needed to cut the the plasma concentration of a drug in half (and those measurements are not the same nor the same amount of time required necessarily ).... A clinically relevant clarification, though, again, maybe not important for USMLE purposes. I am a physician/pharmacist.

[@Alihaider-he1be]

Dude, what you are talking about is clearance not half life he explained right

[@carpe996]

@@Alihaider-he1be you have it backwards.

[@aqsafatima9102]

Please please dirty make one video on renal pharmacology. I wasn't listening to u before. But i just started with one and it went on. Now i really really feel something missing when doing renal pharmacology. Please make one!

[@pcdihealth]

Great Video

[@Profs17443]

thanks this is really helpful

[@niloofarkh4779]

thank u so much

[@indiandancey]

THANK YOU dirty!!!!!!!!!

[@Nomad278]

Where can i find a video of Henderson-Hasselbalch equation?

[@onkara4363]

Thank you❤

[@somethingsafoot]

FOR ALGORITHM TAKE MY POWER I TAKE THIS NEXT SEMESTER

[@jaymata1218]

11:03... thank you kind sir

[@martinkral7222]

Does this apply to vaccines?

[@jeminiperera]

Good one

[@raynaboyarsky4591]

thank you !!!!

[@danielmacedo4417]

Are those equations about Loading Dose and Maintenance Dose High-Yield for the Step 1 or not that much?

[@lalitsiriatti1717]

High yield.

[@rebazothman1506]

Tysm!

[@1412Z]

Thanks!

[@plutobaby9996]

this video is so clutch

[@jonasesenwein3189]

Nice

[@jaehaerys9194]

300likes... i am not going to ruin it by clicking it... but i really do like the video

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Nucypher and DOGEcoin to the MOON! 🚀🚀🚀

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sir stop talking about crypto in a medical channel

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[@franciszoballah4722]

Great

[@kmags8065]

HI this is very useful and informative video ,but what about pharmacodynamics ,do we need to subscribe first to get the rest of the video?

[@jaxonvictoria4345]

The bulk of pharmacodynamics is pharmacology and all the clinical topics.

[@nuckchorris1396]

U the best

[@abdu170]

Thank you very much!

[@annemarshall752]

The fee for monthly membership is not 4.99 it's showing 9.99. Is this correct?

[@alimahmoud9334]

good

[@smallpharm13450]

OK sir

[@user-fv8cr7zz2c]

Powerful

[@DrUsamaCh98]

👍

[@medicallife3738]

Hey dirty please make video on pprf lesion

[@drismail469]

thank you so much

[@SalmaSaifuddin]

i wish i could send you my tuition money instead of giving it to my school

[@joshmcgoo]

COMMENTING FOR THE LGORITHM

[@alvaro37nf]

Dirty, what is your opinion about AMBOSS?

[@DirtyMedicine]

my opinion is that its okay to use but that I think UW is better if you have to pick one

[@alvaro37nf]

@@DirtyMedicine thank you for your response!

[@ekanki07]

@@DirtyMedicine How essential do you feel Boards and Beyond is to Step 1 Study? (if using UW and your videos)

[@tubby7817]

For algorithm

[@hritvikjain__3594]

commenting down here for the algorithm

[@user-js8nu6gu1i]

[@nafissajid1]

🎉😅❤

[@Physiciansdesk]

Aspirin phenytoin and …? Zero order ! Answer

[@yeyo101]

1 day too late

[@medizinundnatur1494]

Please change the name of the channel. There is no dirt in medicine