Sigma - A Comprehensive Overview Of Testosterone Boosting Supplements That Actually Work

💊 Order Sigma Here: gorillamind.com/products/sigm...
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📌 Table Of Contents:
• [0:00] - Sigma introduction and my issue with many Testosterone boosting compounds
• [2:35] - 300-400 ng/dL Total Testosterone increases. The Joe Rogan podcast episode that piqued my interest with Andrew Huberman
• [5:40] - My initial impression of Tongkat Ali and SERMs for boosting Testosterone levels
• [8:12] - The ambiguity of the mechanism of action of Tongkat Ali and Fadogia Agrestis
• [9:32] - Andrew Huberman and I discuss each Testosterone boosting supplement he found to be effective
• [34:39] - Sigma Ingredients Breakdown - 2 capsules/4 capsules
○ [38:04] - Magnesium Bisglycinate - 100 mg/200 mg
∙ [38:12] - The different formats of Magnesium
∙ [40:03] - The different formats of Zinc
∙ [41:01] - Effects of Magnesium supplementation on Testosterone levels
○ [43:03] - Zinc Bisglycinate - 15 mg/30 mg
∙ [43:09] - Effects of Zinc on Testosterone synthesis
∙ [44:11] - Zinc status and serum Testosterone levels of healthy adults
○ [45:11] - Vitamin D3 - 1500 IU/3000 IU
∙ [45:14] - Why so many people are deficient in Vitamin D
∙ [45:24] - My blood test results
∙ [45:44] - The importance of adequate Vitamin D levels
∙ [46:53] - Testicular synthesis and Vitamin D action
∙ [47:47] - Effect of Vitamin D supplementation on Testosterone levels
∙ [48:39] - Association of Vitamin D status with serum androgen levels
∙ [50:38] - Best sources of dietary Vitamin D
○ [52:46] Fadogia Agrestis Extract 10:1 - 300 mg/600 mg
∙ [52:46] - The Fadogia Agrestis hype
∙ [54:58] - Why Sigma featured the dosage breakdown it does at 1-4 capsules, companies putting 600 mg in 1 capsule and forcing you to cross your fingers
∙ [56:46] - The speculated mechanism of action
∙ [59:52] - How to cycle “Sigma” and most responsibly use it
∙ [1:00:40] - Fadogia Agrestis human equivalent dosage breakdown
∙ [1:02:28] - Why you should track your biomarkers and fertility parameters and who “Sigma” is best suited for
∙ [1:05:00] - 2-6 fold increases in Testosterone levels in male albino rats
∙ [1:07:37] - Suggested mechanism of action
∙ [1:14:20] - Testicular toxicity in male albino rats
∙ [1:17:00] - Liver and kidney toxicity metrics
∙ [1:17:59] - Fadogia cycle length in the efficacy study vs. the side effects study
∙ [1:19:35] - The utility of natural supplements in comparison to exogenous hormone use
∙ [1:20:54] - Fadogia cycle length (continued), lowest effective dose with responsible titration if warranted, and Andrew Huberman’s disclaimer on tracking your data
∙ [1:24:04] - Testicular toxicity data with Tamoxifen/Nolvadex, Clomid and HCG and what happens at high enough doses in anything pro-fertility | Fadogia Agrestis efficacy relative to side effect profile
∙ [1:37:06] - Who are the best candidates for taking “Sigma” and things to consider before you use it
○ [1:42:21] - Tongkat Ali 200:1 (Indonesian origin) - 200 mg/400 mg
∙ [1:42:21] - Mechanism of action
∙ [1:46:13] - The standardization and country of origin of our Tongkat Ali
∙ [1:46:49] - Randomized 12 week clinical trial
∙ [1:47:51] - Tongkat Ali dosages
∙ [1:48:55] - Tongkat Ali in managing idiopathic male infertility
∙ [1:50:15] - Tongkat Ali as testosterone booster for managing men with late-onset hypogonadism?
∙ [1:53:21] - The effect of Tongkat Ali on the regulation of reproductive hormones in young men
∙ [1:54:38] - Further insight into Tongkat Ali’s mechanism(s) of action
∙ [1:57:23] - The effect of Tongkat Ali on the regulation of reproductive hormones in young men study continued
∙ [1:58:48] - Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects
○ [1:59:42] - Ashwagandha (standardized to 5% total withanolides) - 150 mg/300 mg
∙ [1:59:42] - Ashwagandha mechanism of action, dosage and cycle duration
∙ [2:01:16] - Ashwagandha effect on semen quality in stress-related male fertility
∙ [2:03:00] - An investigation into the stress-relieving and pharmacological actions of Ashwagandha Extract
∙ [2:05:08] - Examining the effect of Ashwagandha supplementation on muscle strength, size, recovery, and Testosterone production
∙ [2:07:28] - Effects of Ashwagandha on Reproductive System: A Systematic Review of the Available Evidence
∙ [2:08:20] - Responsible use of Ashwagandha and other Testosterone boosting supplements
○ [2:09:00] - Boron 3 mg/6 mg
∙ [2:09:10] - Boron mechanism of action and utility for increasing Free Testosterone levels
∙ [2:11:21] - Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
• [2:15:48] - Conclusion - What to expect from Sigma and who this product is best suited for

[@MorePlatesMoreDates]

📌 Table Of Contents: • [0:00] - Sigma introduction and my issue with many Testosterone boosting compounds • [2:35] - 300-400 ng/dL Total Testosterone increases. The Joe Rogan podcast episode that piqued my interest with Andrew Huberman • [5:40] - My initial impression of Tongkat Ali and SERMs for boosting Testosterone levels • [8:12] - The ambiguity of the mechanism of action of Tongkat Ali and Fadogia Agrestis • [9:32] - Andrew Huberman and I discuss each Testosterone boosting supplement he found to be efficacious during experimentation, their mechanism of action, side effect profile, cycling, sourcing, what to expect, and more • [34:39] - Sigma Ingredients Breakdown - 2 capsules/4 capsules ○ [38:04] - Magnesium Bisglycinate - 100 mg/200 mg ∙ [38:12] - The different formats of Magnesium. Comparing Bisglycinate/Glycinate/Diglycinate to other forms of Magnesium ∙ [40:03] - The different formats of Zinc. Comparing Bisglycinate/Glycinate/Diglycinate to other forms of Zinc ∙ [41:01] - Effects of Magnesium supplementation on Testosterone levels ∙ [42:11] - The prevalence of low Magnesium intake from daily diet ○ [43:03] - Zinc Bisglycinate - 15 mg/30 mg ∙ [43:09] - Effects of Zinc on Testosterone synthesis ∙ [43:51] - Zinc intake from daily diet and supplementation when warranted ∙ [44:11] - Zinc status and serum Testosterone levels of healthy adults ∙ [44:31] - Associations of urinary metal concentrations and circulating Testosterone levels ○ [45:11] - Vitamin D3 - 1500 IU/3000 IU ∙ [45:14] - Why so many people are deficient in Vitamin D ∙ [45:24] - My blood test results for Vitamin D levels on different dosages of supplemental Vitamin D3 ∙ [45:44] - The importance of adequate Vitamin D levels not only for Testosterone production, but also for overall response to hormones ∙ [46:53] - Testicular synthesis and Vitamin D action ∙ [47:47] - Effect of Vitamin D supplementation on Testosterone levels in men ∙ [48:39] - Association of Vitamin D status with serum androgen levels in men ∙ [50:38] - Best sources of dietary Vitamin D ○ [52:46] Fadogia Agrestis Extract 10:1 - 300 mg/600 mg ∙ [52:46] - The Fadogia Agrestis hype ∙ [54:58] - Why Sigma featured the dosage breakdown it does at 1-4 capsules, companies putting 600 mg in 1 capsule and forcing you to cross your fingers ∙ [56:46] - The speculated mechanism of action ∙ [59:52] - How to cycle “Sigma” and most responsibly use it ∙ [1:00:40] - Fadogia Agrestis human equivalent dosage breakdown ∙ [1:02:28] - Why you should track your biomarkers and fertility parameters and who “Sigma” is best suited for ∙ [1:05:00] - 2-6 fold increases in Testosterone levels in male albino rats ∙ [1:07:37] - Suggested mechanism of action via the data ∙ [1:14:20] - Testicular toxicity in male albino rats ∙ [1:17:00] - Liver and kidney toxicity metrics ∙ [1:17:59] - Fadogia cycle length in the efficacy study vs. the side effects study, and the equivalent amount of time in humans ∙ [1:19:35] - The utility of natural supplements in comparison to exogenous hormone use ∙ [1:20:54] - Fadogia cycle length (continued), lowest effective dose with responsible titration if warranted, and Andrew Huberman’s disclaimer on tracking your data ∙ [1:24:04] - Testicular toxicity data with Tamoxifen/Nolvadex, Clomid and HCG and what happens at high enough doses in anything pro-fertility | Fadogia Agrestis efficacy relative to side effect profile ∙ [1:37:06] - Who are the best candidates for taking “Sigma” and things to consider before you use it ○ [1:42:21] - Tongkat Ali 200:1 (Indonesian origin) - 200 mg/400 mg ∙ [1:42:21] - Mechanism of action ∙ [1:46:13] - The standardization and country of origin of our Tongkat Ali ∙ [1:46:49] - Randomized 12 week clinical trial on the use of 300 mg Tongkat Ali per day for the improvement of quality of life and sexual well-being in men | 109 subjects between 30-55 years old ∙ [1:47:51] - Tongkat Ali dosages ∙ [1:48:55] - Tongkat Ali in managing idiopathic male infertility | 200 mg of Tongkat Ali per day with semen analysis follow-ups performed every 3 months for 9 months | 75 patients (average age of 32.7 years) completed 1 full cycle ∙ [1:50:15] - Tongkat Ali as testosterone booster for managing men with late-onset hypogonadism? | 76 hypogonadal patients (average age of 51 years old) given 200 mg of Tongkat Ali per day for 1 month experienced an average 46.8% increase in Testosterone ∙ [1:53:21] - The effect of Tongkat Ali on the regulation of reproductive hormones in young men | 32 males (24.4 ± 4.7 years old) in a placebo-controlled, double-blind, matched-paired study received 600 mg of Tongkat Ali per day or placebo for 2 weeks | 15% increase in Total Testosterone, 34% increase in Free Testosterone in the Tongkat Ali group ∙ [1:54:38] - Further insight into Tongkat Ali’s mechanism(s) of action and Testosterone boosting capabilities ∙ [1:57:23] - The effect of Tongkat Ali on the regulation of reproductive hormones in young men study continued ∙ [1:58:48] - Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects | 63 subjects (32 men and 31 women) screened for moderate stress and supplemented 200 mg of Tongkat Ali or placebo for 4 weeks | Stress hormone profile (salivary Cortisol and Testosterone) was significantly improved by Tongkat Ali, with reduced cortisol exposure (−16%) and increased Testosterone status (+37%) ○ [1:59:42] - Ashwagandha (standardized to 5% total withanolides) - 150 mg/300 mg ∙ [1:59:42] - Ashwagandha mechanism of action, dosage and cycle duration ∙ [2:01:16] - Ashwagandha effect on semen quality in stress-related male fertility | 60 subjects ∙ [2:03:00] - An investigation into the stress-relieving and pharmacological actions of Ashwagandha Extract | 60 day, randomized, double-blind, placebo-controlled study in 60 stressed, healthy adults taking 240 mg of Ashwagandha Extract or placebo each day | The men studied saw an average 23% drop in morning cortisol and 11.4% increase in Total Testosterone levels ∙ [2:05:08] - Examining the effect of Ashwagandha supplementation on muscle strength, size, recovery, and Testosterone production | 8 weeks, randomized, prospective, double-blind, placebo-controlled clinical study, 57 young male subjects (18-50 years old) with little experience in resistance training were randomized into treatment (29 subjects) and placebo (28 subjects) groups. Subjects in the treatment group consumed 300 mg of Ashwagandha root extract twice daily, while the control group consumed starch placebos ∙ [2:07:28] - Effects of Ashwagandha on Reproductive System: A Systematic Review of the Available Evidence ∙ [2:08:20] - Responsible use of Ashwagandha and other Testosterone boosting supplements ○ [2:09:00] - Boron 3 mg/6 mg ∙ [2:09:10] - Boron mechanism of action and utility for increasing Free Testosterone levels ∙ [2:11:21] - Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines • [2:15:48] - Conclusion - What to expect from Sigma and who this product is best suited for

[@deanshields8031]

What’s your opinion on the recent Matt does fitness video proving he’s a natty?

[@cascadianapplications7124]

This timing list is amazing

[@mattepton5731]

Amazing breakdown…

[@Saint2CB]

Hey just letting you know if you put in this timing list in the description of the video it will automatically show up in the video as well!

[@MorePlatesMoreDates]

@@Saint2CB it doesn't fit in the video description.

[@thecobaltblue9311]

This man really made a 2 hour long documentary about why you probably don’t need his new product but if you do here’s everything ever researched about what’s in it and still recommends other lifestyle changes before considering his product. Never change, Derek. You’re one of the last beacons of hope for us gym rats

[@thewalletwarrior]

I was about to say the same thing 😂. Aren’t most of those supplements bunk anyway.

[@jamesbernedo3204]

@@thewalletwarrior yeah most of those supplements are junk.

[@dragos8839]

i mean the zinc is pretty good and if the tongkat and other thing really increase testosterone tremendously why not. But the ones sold by derek have way too low quantities you'd need like 6 capsules a day and that would run through the bottle in like 40 days so ultimately it's cheaper to just buy gear lol

[@depraved420]

That's why we watch him.

[@the1der]

Tong Kat 100% works

[@davisia81791]

Derek just casually dropping an entire fucking movie about Testosterone over here.

[@JairajSinghPatil]

Didn't even add the 20th century FOX logo smh

[@ka3274]

I don't think I've talked for 2 and a quarter hours all week combined let alone in 1 sitting. Derek just hits record and away we go

[@THICCTHICCTHICC]

Spielberg could never

[@brycethoreson9216]

Holly shit, your comment made me realize the video is 2.5 hours

[@freedmni]

And a cohesive presentation of an extensive literature review- breaking down multiple multiple sources for each of the ingredients listed in the beginning. Very impressive work.

[@aliabinassif9221]

Derek has an insane buisness model going. Educate people on these compounds and give people the knowledge to see why his product is superior

[@cantguardmike5661]

Facts. Him and Jim Stoppani are my go too

[@JanoyCresva]

If you fall for it. Its LITERALLY what EVERY fitness salesman does. To a T. Derek just presents it as a "bro" instead of a guy in a suit so you buy it more.

[@DELTA9XTC]

@@JanoyCresva except almost NO other fitness salesman knows anything about the products they push. They are just that - salesman, but without having done extensive research over yrs, as well as personal experience etc. Im not gonna buy a test booster and thats not what Derek is trying, he wouldnt recommend me a test booster bc im not in one of the specific situations where a product like this COULD (that means it can maybe, of you are lucky and if your body reacts good) possibly help. Thats everything but a classic salesman. Also you obviously have no fucking clue about Derek and his channel here how he started on KZbin, how he grinded like a madman, how he put in the work big time, how he always tried to stay objective and evidence based. The ONLY critique i had about Derek really so far is his Athletic Greens sponsoring/pushing. I think that product is extremely overpriced and shit bc of the propietary blend. I already wrote a comment about this once. And im following and watching MPMD since many years.

[@k4yser]

@@JanoyCresva I'm waiting as well. Where the hell is your comeback? Or did you pass out sniffing your smug farts?

[@wanderoutdoors6094]

It's called marketing

[@someguyfromengland5036]

Derek is easily the hardest working guy on this platform, the man genuinly cares about his community and makes sure his shit is squared away. So happy to see him getting all this success ❤

[@someguyfromengland5036]

@@Brickinasock ?

[@skatei]

There's a lot of hard working guys on this platform...

[@kd9937]

Idk man he d9nt got no dual engine monster truck

[@thisis3379]

SIGMA just made me feel lethargic and LITERALLY made my vision rapidly worse which lasted for about 5 days after only taking for two days. VERY fuzzy visuael focus and dull pressure in my eyes that really shouldn't ever happen. And eff you for sending my $1000 of rancid bacterially-tained products, Derek.

[@filabila]

Greg doucette drops his Alpha Test booster tomorrow after studying dereks ingredients for 25 seconds. Boosting harder than last time

[@notstewie5103]

Except it will have beta-alanine in it 😂

[@mr.c7411]

😂😂😂😂😂😂😂🙌

[@sir0nion]

He wouldn't have to if you just BOUGHT HIS FRIGGIN' COOKBOOK

[@homeslice4551]

The supplement to repair your plummeted test levels after eating minimal fat on Greg's Cookbook

[@fernandopineda3409]

@@notstewie5103 😂

[@jondabron5496]

I can now ascend to the legendary enhanced sigma male

[@dontworryiamsmurf5307]

You already are Doc

[@treiskushrenada6332]

Bro, I just want to tell you that I love this statement much more than I should. I believe you dropped this 🤜🏾👑🤛🏾

[@JulioVargas-ok5st]

ME TOO! LETS GOOOOO!!

[@shay8514]

Yeah but bttv is like a third party thing....

[@scaldedape6213]

The upgraded bottles bring you to Legendary Superior and then Grand Master sigma male.

[@danielnicholson25]

I haven't exercised in years, but stumbling across your channel has motivated me to give it another go. The thing I love about your channel is the level of transparency and honesty. Also, the in depth knowledge that you have and share, as well as just the laid-backness and funny shit. I plan on trying the gorilla mind smooth and prob some other stuff you have. Awesome content dude!

[@danielsponseller7508]

Thats how i got back into working out more seriously. Definitely start with creatine, helps immensly with recovery.

[@holographicfrog1503]

Jeff Nippards fundamentals program is amazing if you want to do a hypertrophy program.

[@thisis3379]

SIGMA just made me feel lethargic and LITERALLY made my vision rapidly worse which lasted for about 5 days after only taking for two days. VERY fuzzy visuael focus and dull pressure in my eyes that really shouldn't ever happen. And eff you for sending my $1000 of rancid bacterially-tained products, Derek.

[@gregorymanternach7626]

It’s amazing how in-touch Derek is with his customer base

[@oldmanrants7784]

Listening to MPMD is also a Testosterone Boosting Supplement that actually Works.

[@ShermanKyle]

Derek really moving into the big leagues with drops like this. I knew a supp collab with Huberman was inevitable but this soon? Wow bro, diggin this product path.

[@hunterupton5809]

Derek likes money. why are you surprised? lots of people want to believe there is a supplement that will boost testosterone without steroids or SARMS. this is just a business move

[@gymguy281]

@@czx5555 imagine watching a two hour video just to ignore everything that was just said and backed by research

[@Jiujitsuspecialist]

@@czx5555 Meh who gives a shit, if it works just little its still a win over a fucking needle.

[@liamharvey737]

Derek is truly the goat, because of his pre workout breakdown i was able to understand each ingredient and their functions, the best pre workout I’ve ever had for sure. Its insane how much work this guy puts into his products, and he carefully takes the time to explain each and every detail about it. I appreciate everything he does for his own community derek will always be delt god 🙏

[@thisis3379]

SIGMA just made me feel lethargic and LITERALLY made my vision rapidly worse which lasted for about 5 days after only taking for two days. VERY fuzzy visuael focus and dull pressure in my eyes that really shouldn't ever happen. And eff you for sending my $1000 of rancid bacterially-tained products, Derek.

[@mustangNZx]

Been watching Derek since like 2017-18 and its crazy how much healthier and younger he looks now compared to back then, keep up the great work g

[@stevenm732]

Nothing better that a massive comprehensive breakdown from Derek. Thank you sir for the work you do.

[@angelofloresHL4]

Boost your test by: 1-Eat enough fats (mono-poli-un) 2-Eat your carbs & protein (Don't avoid food groups) 3-Enough micros specially: Vit D, zinc 4-Improve sleep quality (Valerian root, chamomile, Passion flowers, tilo, gaba) 5-Resistance train enough but do not overtrain 6-Take your daily sun (15-30min) 7-Eat enough kcal 8-Don't watch porn 9-Take your supplements: ashwgandha, tongkat Ali 10-Don't hold too low of a BF % 11-Don't hold too high of a BF %

[@liquidbrainstorm]

12-15% optimal for health.

[@ka3274]

You had me until step 8

[@chrisarmstrong3727]

@@ka3274 you and me both brother 🤣

[@babajaga8180]

I would add 6mg of boron and 5gr of maca to the list.

[@starmorpheus]

@@chrisarmstrong3727 I hope you're joking. Porn is a disease to the brain. Watching simulated intercourse affects a lot more than testosterone.

[@GlorifiedGremlin]

I feel like Andrew had a lot more fun than he typically does on podcasts. He was constantly smiling to himself like he was thoroughly enjoying the conversation

[@ARMWRESTLINGCYCLINGFRANCE]

Damn this drop is so next level. Thanks man. I've been deep reading about these compounds after seeing the podcast you had with him. This really brings everything together. Chapeau.

[@YoIamShouta]

Bro I started watching the video expecting it to be the usual length but this is a god damn blockbuster

[@88888j]

Am I a sucker for trusting Derek and buying the supp before getting 5 mins into the video????

[@dulafit]

dont we all trust derek

[@bryanseelnacht6772]

Same bro

[@BlitzBloodFan]

Most trustworthy guy IMO on youtube with their own brand, but I am still skeptical because money still talks loudest so he can be downplaying side effects, etc. Having said that, I still might give it a try since I basically try everything he sells to see what sticks with me.

[@Lordlynx88]

Nope, Derek can take my money! Most transparent individual out there!

[@medz3398]

He contains all the major important ones in sigma

[@poochkane]

Please make more, your boy needs this product! (Currently taking these ingredients separately for 4X the cost)!

[@bakubaku6204]

This content is amazing/informative and very much appreciated. I'm still struggling to get everything dialed in but this channel has helped a lot. Much appreciated

[@ifgwelf]

Derek with an essay in the pinned post. Thank you for your service King. Have helped me level up in ways you'll never know.

[@garyhost354]

Looking hawt AF bro.

[@ifgwelf]

@@garyhost354 thanks brah. Appreciate it

[@trnadokick]

Just picked up a bottle Derrick!! Love the content and passion you share with your fans. All knowledge no BS!! Keep up the good work!!

[@Lee-xs2jt]

I was on test for a while. after getting off and finishing my pct i hopped on FA and Tongkat. I find it helped me keep my gains as much as possible. It def worked. I just ordered SIGMA since I was running low. Thanks Derek.

[@JoshuaCurey]

Jesus bro, thank you so much for these videos. I’ve been watching your content on and off for a while, but now I’ve started focusing on increasing my knowledge on the pharmacology aspect of things, your videos are always a great help.

[@captredbeard]

Damn, was just going to buy a lot of those ingredients separately. Hell yeah man, keep the good shit coming.

[@jgoldian47]

Sadly I did this already before thus video released :(

[@captredbeard]

@@jgoldian47 Zamn. Buy it anyway! crying laughing face x2

[@jgoldian47]

@@captredbeard i did x)

[@meditate365]

isn't buying those ingredients separately cheaper? and get more dosage? genuinely curious

[@jgoldian47]

@@meditate365 probably but I Wanna support derek and everyone plus there are a few things in the ingredients that also show benefits

[@thomashanham723]

Loving the collab with Andrew Huberman. Just two guys who base their opinions on actual evidence, and don't try to con people with false information like 95% of the fitness industry.

[@starmorpheus]

Not to sound like a hater, but have you read any of the research that they're citing? Appeal to authority is a strong with this fan base. "Everyone else is bullshit, but you're the one giving the real news" How do you know they're not bullshitting you as well?

[@thomashanham723]

@@starmorpheus not as much as I'd like. I tend to go back and read the articles I'm personally interested in, like the ones relating to mental illness, or when I want to start taking a new supplement he talks about, like fish oil. So far I haven't come across any red flags in those, and the research seems solid. However, I tend to take his word for other things (like diet) because it really isn't that interesting to me, so I can't account for the quality of the studies he cites there.

[@Artificial_Historian]

Finally here, kzbin.info/www/bejne/d5q0gZ2sgKl5Ztk&ab_channel=Dr.AAM-

[@marquiseburks]

@@Wolf_ManJack he's not saying they are not reputable, he's just stating that this fanbase tends to believe everything Derek/Huberman says without doing any fact checking.

[@oxxy6678]

Andrew seems to be much less knowledgeable than derek on this stuff. Whenever they talk I feel like Andrew is kinda just nodding his head and doing a word salad and not really understanding what derek is saying

[@Jake-eh6zd]

Amazing! I love these deep dives. Keep up the great work Derek.

[@Daero1]

This is so artfully and professionally crafted. Even if I don’t buy this product because I might not need it, I’m still going to purchase your protein powder. I have to support this some way.

[@justinjacobson1414]

Very cool. Congrats on all the success Derek.

[@Pruflas-Watts]

Ordered it Sigma. I started taking Fadogia and Tongkat in late Jan after watching Doc talk to Joe Rogan about it. Only problem is dubious sourcing and it was difficult to vet which company to purchase them from. I'm very glad you jumped on it so I can try it from an actual reputable source.

[@christophermanabat1934]

Did it work for you? Did you notice a difference? I’m currently at 140 T levels and TRT isn’t an option since my wife still wants to have more kids. Looking for natural methods that actually work and not expensive piss.

[@Ravage017]

@@christophermanabat1934 who says you cant have kids while on trt? just take hcg and you'll be fine

[@MoreTooArt]

Thank you so much for the complete breakdown. Long video but greatly appreciated.

[@kajetanpietrzak7891]

Not kidding when I say this man could sell me literally anything

[@JohnTurri]

Facts. I trust him so much.

[@Ant-ym3mw]

@@JohnTurri same here man, currently watching. Just want slightly better gains lol

[@chanito_nyc]

Yeah, I definitely understand what you guys are talking about, terminology and everything

[@TheCmack21]

Awesome stuff. Thank you. I would be very interested to see what a video with Dr Gillett and yourself would be like talking about EDCs and their effects.

[@helojoe92]

Hey Derek, awesome looking product! Have you thought about doing a clinical trial of your supplements yourself? Like paying a researcher to do a "small" double-blind, placebo controlled study with around 100 people? The dependent variable of course being Total T & Free T (with maybe also having subgroups of "weight training" and "no training", since I guess there could also be an interaction with lifestyle) If the efficacy is anywhere near the numbers that Huberman and the literature suggest, you should easily get a statistically significant result with such a "small" sample size.

[@helojoe92]

and with your social media reach, I guess it should be quite easy to recruit enough participants!

[@123bruhhhhhh]

+1 for this

[@jtownsend13]

Yes, this would be great!

[@podnucmo5]

This^

[@WildeMike49]

The "Conflict of Interest" section would not read "the authors declare no conflicts of interest at this time" and thus no journal would publish it. It's going to have to be one of us to make it happen.

[@devinwolf3340]

In reading about the ingredients, and purchasing Sigma, I came across another herb that has been studied fairly extensively. Just read a meta-analysis on Kaempferia Perviflora and the verifiable effects are significant increases in grip strength, increased erectile response, increased brown adipose catabolism, and an uptick in endogenous nitric oxide production, as well as analgesic effects on par with OTC nsaids. At six months, doses even up to 100x the efficacious dose in mice showed no signs of organ lesions. Pairing with Sigma for the. . . uh. . . grip strength. . . It’d be cool to get your take on Kaempferia, too.

[@lord_man_king]

The fadogia segment is so damn exciting to hear. I’m about to begin my trt protocol soon and knowing that i possibly won’t have to introduce HCG into my trt (possibly “sports” trt) level of hormone supplementation is so dope. After I use up my current stash of tongkat Ali and fadogia argrestis, I may consider picking up SIGMA.

[@somethingginterestingg4275]

Why would you take a test booster on trt?

[@lord_man_king]

@@somethingginterestingg4275 I’m only interested in the HCG-esque properties of the fadogia agrestis component. From what I listened to so far, fadogia agrestis acts as an LH mimic and having an orally bioavailable version of HCG (a known LH mimic) just sounds attractive…and by the very off chance that everything else in SIGMA works synergistically with fadogia, I think it’s be a worthwhile purchase for someone on TRT. Derek just concluded that it might not have that dramatic an effect for a person on anabolics, but some anecdotal evidence online of people maintaining testicular function and size while shutdown by exogenous testosterone usage, backs up what Derek said about fadogia agrestis and its effects on testicular function.

[@black9897]

@@lord_man_king same. I've been taking FA while being on TRT.

[@maximalsakerhet7930]

Derek is a real g in the fitness youtube scene. A real one for sure, this breakdown was saucy af. Thank you Derek

[@nimsu]

Very cool seeing you develop this. I have purchased my first bottle today.

[@MysticalPolymath]

i wish i could just get a 1 on 1 session with huberman on what i should do, this stuff is so dense and requires so much research and knowledge its really overwhelming. so many different compounds to try, and so many nuances and interactions with diet, lifestyle and goals

[@josiahhein6036]

None of these guys could tell you what to do without lab results. If yget blood tests with lab results, you could easily identify what vitamins and minerals you are deficient in and start adding them to your diet. Then, get all your hormone levels tested and start supplementing for deficiencies there as well. This is the only way to know what's actually going on with your body and what else might be needed. Outside of that, eat your macro nutrients and exercise at least 3 days/week.

[@benmarshall3931]

I cant believe the timing of this.. My partner and I are just about to start a pre conception detox, i have a sups stack for her already and was wanting to find something for me too. Were a bit older than teh norm for kids i think. im 42 shes 38. Shes very healthy, always eaten well, good genetics and general health. i think i have good genetics...i must have to be in the health im in considering the eh...recklessness ive displayed with my own health over the years. i eat well, hate exercise, but do it sometimes. I have a physical job and exercise feels more like a punishment than a reward. Still, need to do more. I believe im in good health but should probably do some tests. Ive ordered the Sigma already. The Huberman podcast is among some of my favorites, so you and him teaming up is excellent, as i feel literally dont have to worry about the genuinity of teh supplements ingredients... Theres a ton of information for woman about pre pregnancy preparation etc...I wondered if you could do a podcast on Male preparation for conceiving a child, especially in later life?/ That would be amazing. Im a huge fan, I made it to the end of this podcast in one go too :). Cant wait for the 2 Mill subs episode.

[@hotsky83]

Actually watched the full video. Good info!

[@justsomebodypassingby3970]

Just ordered a bottle of sigma and subscribed. Good information on here. Keep it coming Boss

[@SplashFireFilms]

sounds great, hope it will be available in europe sometime

[@jasonboyd5165]

Great combination of supplements. I have been sourcing the majority of this mix separately with a lot of effort and difficulty. Can you comment on the potential competing activities of Tongkat Ali and Turkesterone for the estrogen receptor? I am returning to weight training after a long hiatus. Approaching 50 and needing to address some age related declines and life style issues I have overhauled all aspects of my diet, supplementation, training and recovery. I had planned to cycle Sigma with Turkesterone as part of this process. Thanks for the great breakdown.

[@SuperMatters]

I too am interested in the answer to ur questions, I was thinking of doing the same

[@just_a_guy13]

Can you make a Playlist of you reviewing only your products like this video(long-form)?

[@christopher3d475]

I was on TRT for 2 years, but had to come off it because I developed really bad secondary polycythemia. I was having to donate blood, I was dizzy and my blood pressure was always way elevated. I've been looking for ways to boost mine T.

[@connarchicoski91]

Any contraindications using this supplement and Turkesterone?

[@subyguythatlovestodrive]

Ordered a bottle yesterday! I'm really excited to give this a go. I need to get my base line bloods done but I feel like I'm border line hypogonadal or just have some messed up levels in general. I've locked in my diet, dialed in the sleep. But just feel worthless everyday, my body is constantly sore AF and my recovery is a serious joke. I'm 34 5'10 195lbs around 20%bf now. I was 280 probly 55%bf at my heaviest and yo yo my weight/diet for decades and consumed a liver murdering amount of liquir in my youth. But I've been at this current state for about 3years now and just wanna be able to workout 4 days a week without being wrecked. Thanks for everything you do Derek!

[@Jordonwilliamoakley]

You couldn’t take the time to research studies behind testosterone boosters 😂😂 they’re proven not to work you old man

[@starboy2013]

Tried checking iodine.

[@arjunaaa9668]

derek im from indonesia and ive been using tongkat ali for months, dosages are 3-5@500mg capsules per day. i would say its an awesome product it improves my mood and mental state. also noticed some strength gains at the gym. awesome content👍

[@ChrisB-yn6zz]

Started watching this last night. Woke up this morning, to finish the last 20 minutes I missed last night. Super pumped to give it a shot! Ordered a bottle last night before falling asleep. Should be here tomorrow! Thanks Derek! Always helping the squad and doing the research for everyone to optimize and live their best life!!

[@k_d1826]

Hey, did you try this, how did it go? What’s your thoughts on this product? Would you recommend it?

[@adrianpawejachimowicz5014]

update?

[@ChrisB-yn6zz]

@@adrianpawejachimowicz5014 didn’t work I’m on TRT now.

[@Treeskid1]

did you notice any issues with the the fadogia? or come across better studies? I just purchased sigma and am now skeptical bc of fadogia

[@colorsofsound4782]

Late comment here, but again, like Derek and Huberman mentioned, this is not going to be anywhere near the ballpark of using gear, this is just a booster that will give an extra hand to test especially if you have got an optimised lifestyle and perhaps not getting enough D3, magnesium, zinc from diet. TRT is a long-term commitment that has severe side effects (nothing against it, but it is important to know that it shuts down your fucking balls amongst other things). You are NOT going to feel that big of an effect. Having said that ,the chance is small that Sigma is going to do harm to your body (if titrated and cycled as instructed). So it is up to you, if you have the financial resource for it I don't see a reason why you wouldn't try it. Personally, I felt a very small but still noticeable effect in recovering a little bit faster and getting less tired after work shifts and getting one more rep in during workouts, its not amazing but it is something and I'm happy with that.

[@tkeslinke5439]

Very cool. Thanks Derek!

[@MikeJohnCore]

Copped. End of story. Mad respect for Andrew and Derek. Good honest guys that don’t hesitate to correct their statements if they’re wrong, which they aren’t. Love this community. LFG AND CONQUER EVERYTHING.

[@imwachos8490]

HELL YEAH!

[@ThE420DbOY]

Ya I bought 6 bottle like 15min into this video 😄

[@Espada1469]

Lmfao

[@ashleytaylor994]

Just take mk677

[@documentthegrind7710]

@@ThE420DbOY 6 bottles will last you a solid 2 years between cycling off and using them all

[@HunthippY]

Man I’m really new to this stuff and Derek has really been clutch on learning the ropes to this sea of mostly shisters. Thanks for not being a charlatan, really loving your content.

[@Undergroundbattler]

Hey Derek, with these product breakdowns would you be willing to do a breakdown on some of the blood tests offered by Merek Health for people looking to get a test done but are hesitant due to not knowing what all of the biomarkers are and not knowing what the measurements of them would mean. A breakdown of what each biomarker is, why it's important, what range of measurements are optimal, and how they tie in with a TRT/hormone optimization protocol would be extremely helpful. I know you can't legally give medical advice, so if any of that counts as advice it would be understandable if you didn't speak about it.

[@itb4255]

Do you think this could be useful in combination with PCT medication to get natural production back?

[@1982chiXu]

Really excited to hear this. I've experimented over the last few months with both Tongkat Ali and Ashwagandha and noticed clear differences in a number of different things like mood, energy etc. so seeing a product that contains a bit of the main, recently discussed natural T boosters from a reputable source is super exciting.

[@larrytate1657]

Tongkat Ali is toxic to organs though.

[@1982chiXu]

@@larrytate1657 Which is why I cycle it, and don't go crazy on the doses, much like what is explained here in the video if you watch it.

[@buckast3907]

I’ve heard about tendons being weakened with tongkat because of estrogen. Any of that accurate? I love ashwagandha btw

[@1982chiXu]

@@buckast3907 It's not something I've personally experienced, ymmv. I think the whole process of cycling off it is important to keep things like that in check though.

[@brandonbolyard3468]

,Thanks for the info man very insightful I appreciate your time spent

[@VazquezFamily09]

Question: Along with Dr. Input, what LAB values or exams should we specifically be checking on and with what frequency ? Again I am asking for a general recommendation I understand we are all different and i must consult my Dr. etc etc. @MorePlatesMoredates

[@alankuo2317]

Max from accounting heard about Tom kat alee from the Joe Rogan podcast, and bought 1 year supply of sigma and increased his free test by 300 ng/dl. Now he can more effectively export excel files into pdf.

[@afonsomendes92]

just the effect I'm looking for!

[@southpawhammer8644]

I'm almost 41 and struggle with low T. I can attest that this combination works! I feel better then I have in years.

[@solomonkane1712]

@@JesusChrist-fz7pj I get going on TRT. I know guys my age or younger on T but I want to try regimens like this before jumping on T. Once on T I expect to not go off until the grave.

[@jonchapman8344]

I started trt last October. 40 years old and tried all boosting supps and for me were suboptimal based on blood panels. Trt is the way. Finding a good pcp is hard luckily im in Texas and have dr jordan.

[@marleydavis2391]

Derek I hope you know your a lot of peoples favorite youtubers. I watch you every day to unwind. Keep doin your thing homie

[@TheOtherGregOlsen]

Derek please do a video on the best method of deployment and location for milk in the fridge. Thanks!

[@bugabutu]

Been road biking for the past 7 months and compared my testosterone from a year ago. I am 28 years old for reference. April 2021 I was at 274. Fast forward to this year I am at 429 after cleaning up my diet and losing 15lbs. Regardless, I am super interested in your sigma supplement so I placed an order lol 😂 Let's see where it takes me

[@nigeleharis5886]

What’s your age? BMX racer and I had tested at 442.

[@bugabutu]

@@nigeleharis5886 I am 28 years old 🤙

[@dandjedi]

Not that you haven’t improved it but doesn’t time of day or just certain days change T levels? I’m sure it’s gone up just playing devils advocate. I’m sure mine has gone up since losing 70 pounds last year now 3 months in putting on muscle. I’m 39 years old and an animal in bed lol. My wife loves it. I’m gonna get mine tested soon. Getting in the best shape of my life.

[@lopez12345ml]

@@dandjedi that’s the thing about testing for T it changes a lot throughout the day

[@bugabutu]

@@dandjedi When I tested a year ago, I got it checked first thing in the morning at 8am when Test is supposedly at its highest. At that time I was just playing tennis so I expected at least 300 but I was super disappointed when I saw 274. I did a recheck in October six months later after having ridden my bike for a month, sleeping better and being more active in general, went over 300 but not 400+ like recently. Hoping to keep my T trending upwards as Derek says, having lifestyle dialed in and supplementing with Sigma

[@justinw1765]

Looks like a great supplement, and I'm tempted to get some, but I tend to like things more separated because then I can modify based on needs, diet changes, etc This is especially true when taking a supplement with minerals. And some minerals/vitamins/nutrients don't work well together in the same digestion/assimilation cycle. Some have a synergistic effect when taken together like iron and vitamin C.

[@SSSS-bu9dl]

Just ordered some, along with a couple other items I needed. Can’t wait to give this a run.

[@jwbatchelder]

Are you worried about Fadogia?

[@BeholdIamaNewCreation]

Big fan of the channel Derek, subbed on multiple accounts now. I plan to use your blood lab testing protocol, get a nice baseline of a blood profile so I know what I am working with. I am a 39 y/o male who had a long period of depression, weight gain, and alcoholism. I am sober two years now and I am taking my health very seriously now. Last time I did a complete blood profile was with my primary care doctor 8 months ago and he just said my Test levels were fine. But for me, wanting to compete in some boxing matches potentially, while also losing weight, and build muscle, increase memory retention. It seems advantageous to give your product (Sigma) a try if needed. I need to wait for some fundulation to come in, but I will surely be taking this seriously, I think you have a history of coordinating a quality lab service that can help me out. I really want to know my test and free test levels. Then do a follow up a few months later after taking Sigma (if indicated). I don't want to use TRT, HCG, or any altering chemical that could affect my own long-term Test production, synthesis, and expression. I already eat fairly healthy, take zinc, magnesium, and a balanced intake of polyunsaturated, mono-unsatured, and saturated fats to aid my body's own production. Cheers

[@Mcmj-ot4dt]

This is awesome. I was wondering why no one had made a supplement with all these proven test optimizers. I'm still going to avoid the Fadogia Agrestis though. That study about the testicular toxicity has me a little worried.

[@TheGodfather101]

keep your dose at 150 mg it wont happen.

[@timratcliff6590]

@@TheGodfather101 per day or pill because the dosage calls for 2 pills a day 300mg

[@MrOddlife]

I dont think it was mentioned in the video but what is the reasoning for the 4 week on 1 week off cycling. Why do you believe that is the most optimal? In the past I've heard Tongkat and Fadogia is best with a 5 day 2 off cycling?

[@elisteele574]

Derek is the realest. This is absolutely amazing. Every video is a banger.

[@SuperFlamejr]

Saw a video from another notable supplement youtuber and he talked about fadogia being toxic. Stopped taking it immediately after so I'm a little on the fence about trying Sigma, but hearing you address that is a relief and I will reconsider.

[@jwbatchelder]

When he broke down the rat studies for things like hcg and other FDA approved etc, and they where just as bad if not worse than Fadogia, it makes me reconsider as well, probably going to give it a shot.

[@michaelsofine]

Think that we evolved from rats! If they get testicle cancer so will you. Maybe.

[@kbc8090]

Would look into adding K2 in both MK-4 and MK-7 forms if this product ever sees an update. Great combination of ingredients here, I'll be purchasing and trying it out!

[@ashleytaylor994]

What does k2 do?

[@kbc8090]

@@ashleytaylor994 Vitamin D makes the body hold onto dietary calcium and over a very long period of time it can make its way into muscle tissues and arteries. MK-7 variant of K2 helps direct calcium out of tissue and arteries back into bone and teeth where it should be. MK-4 has had efficacy in rats in increasing testosterone. D3/K2/Magnesium are a very synergistic combo and a vast amount of people aren't sufficient in any of these 3.

[@ashleytaylor994]

@@kbc8090 god bless you. Do you recommend taking k2 by itself? I have seen d3 with k2 mix . And which company for k2? Thanks

[@davids5006]

@@kbc8090 yup..I take mk7. The k2 will thin your blood to much

[@davids5006]

@@ashleytaylor994 try mk7 with your vitamin D.. research that

[@robertconrad2855]

Can't wait to see the feedback/results on this supplement. I've used most of them separately when attempting to optimize my testosterone. Nice breakdown Derek.

[@doost7846]

Any negative sides?

[@robertconrad2855]

@@doost7846 The advantage of taking them separately, is that I could monitor which supplement was doing what. The downside is it's super expensive. Ashwagandha made me anxious which isn't good because I have problems with getting to sleep. Tongkat Ali / Fodogia and DHEA (not in this supplement) did raise my total T by 120-150 ng/dl over 2 different blood tests. BUT, my issue is low free and estrodial, not so much total. Boron had a small, but direct impact on free T. The best thing I took was the magnesium and L Theanine that improved my quality and length of sleep which had the greatest impact on all hormones. So I ditched the Ashwagandha, Tongkat, and Fadogia and kept the sleep health style nootropic stack. Moral of the story is there are different reasons for hormones not being dialed in...sleep had the most impact on me. If a Testosterone booster fucks your sleep, then it's counter intuitive. The best way to do it, is try these things one by one and do blood test while monitoring symptoms. Or just buy this stuff and see what happens. Might be all good. If not, you won't know which supplement is causing your issue.

[@denaco]

dude, needtobuildmuscle have used these compounds in their n2generate for over 12 years so nothing new. i used them back in the day but havent in years. works but you shouldnt be on them long term.

[@ethanmueller1016]

Videos like this are the reason that you are the only fitness information that I listen to and the only supplements that I will ever buy from

[@chzpuffs1835]

Hey Derek, you probably won't see this but I have a question for you regarding the extract concentrations. The Fadogia is a 10:1 extract, which is in-line with the one that Huberman said he was using. The Tongkat is 400mg at 200:1 in yours, but the Tongkat Huberman mentioned that he used is 400mg of just the root, not an extract. Does that mean that you have 80,000mg worth of Tongkat root in yours, or you have 400mg worth of the root at a 200:1 concentration so it's squished into 2mg of actual product? Would be great to have some clarification as I'm a bit confused. Thank you!

[@Dunamis77]

Was 100% sold and about to buy it until I watched this. Thanks for looking out Delt Daddy, your transparency and clarity behind your products is why I always come back ❤️

[@lewiswilson4083]

What specifically changed your mind?

[@mattasbury3151]

​@@lewiswilson4083he didn't want a healthy testosterone level

[@Alexpa898]

Hi Derek! Would taking sigma be a good choice for someone taking finasteride that just wants to maximize the testosterone levels in order to make up for the lack of dht? Thanks for all your valuable content!

[@colecarlson9129]

I was wondering that too

[@rios39]

Be careful if the boron because it increases DHT. I took some alone and got a pretty big shed once, although I was taking 10 mg of it, which is maybe too much for someone with MPB. I would stick to taking the minimum dosage and see how that works. I’m pretty nuclear with my regimen so I might be able to hold off that off with RU added with fin. I’m also using topical dut that I only use sparingly.

[@kamilmusalat]

I have been taking TOngkat Ali, mondia whitei and sometimes Huanarpo Macho + black maca which is pretty crazy I havent tested my T Levels but you can feel the energy levels up and youre kinda stronger in the gym and a little quicker lean, I can imagine mixing tongkat and fadogia in one capsule is pretty strong stuff, I take them separately on different days

[@jross2229]

Love these deep dives

[@sulttandheyaa2491]

should I keep using my supplements like magnesium, zinc, D3, and ashwaganda while using this product since it already has them included?

[@CoolSilver]

I was really considering this or some other product. After testing with Marek I noticed my LH and FSH was as low normal as my other hormones, hypogonadal in T and E2. I been on TRT for 5 weeks and it's helped a lot. Could Sigma? Possible. My Magnesium and Zinc were great though. Vitamin D was in the deficient range and taking high IU from doc for that too. Either way I'm glad I been watching MPMD before and since starting.

[@natemoody6850]

Derek! What are your thoughts on using sigma or these ingredients as a PCT?

[@nickstrasser6173]

I just received my bottle of sigma this week. I ordered the comprehensive male blood work through Marek health and will get that prior to starting. Upon receiving the draw instructions, I checked my multivitamin and it has Biotin in it. I’ll wait 72hrs to draw. Per Dr Mark Gordon on JRE I started taking pure encapsulations multi: Ultranutrient, as well as quercetin, Vit D, zinc, etc in 2020. After listening to the latest Huberman Lab podcast with Dr Gillett, I’m wondering if I should eliminate the ultranutrient and quercetin from my stack. They discussed turmeric/curcumin being a 5 alpha reductase inhibitor and Dr Huberman recalled severe effects when he took turmeric in the past-the ultranutrient multi contains 100mg turmeric/serving. Dr Mark Gordon discussed the importance of having an ionphore to increase the uptake of zinc, but now I’m wondering if the potential for increased zinc uptake is worth the potential inhibition of 5AR. What are your current thoughts or recommendations on ionopohores like quercetin turmeric etc?

[@NightOwlGamingz]

Nerd

[@RenoMay]

Super excited to hear your take on this. I’ve also been skeptical. But after talking to DrGillett more about it I’m super excited to see how this can help people.

[@jugofmilk41]

Holy shit didn’t expect you here

[@RenoMay]

@@jugofmilk41 I’m actually a gorilla mind affiliate and I’m currently working with marek health as a patient and affiliate as well.

[@paulibabba5566]

I would love to be a gorilla mind affiliate. I buy tons of their products

[@ricksgiggle8852]

@@paulibabba5566 you need subs, Bubba. I'm a gorilla mind affiliate too. this is my burner account.

[@Stopvotingdemocrat]

@@ricksgiggle8852 hey bud is there any products that are good to add to my trt for muscle? And my libido has been down for the last few months is there anything to add to my trt for sex drive

[@davids5006]

Can't wait to get my bottle today... Been sleeping better and eating better but T is low, hoping this does the trick 🤞🏻....... Great info

[@karlphillips2126]

Quickly reviewed the ingredients and I gotta say this is promising. I was taking most of these separately already but I don't mind adding another gorilla mind product to the stack and tossing my normal stuff. Glad to see a new product bro

[@Artificial_Historian]

Finally here, kzbin.info/www/bejne/d5q0gZ2sgKl5Ztk&ab_channel=Dr.AAM-

[@ka3274]

Fun drinking game, every time Derek says a word you don't understand take a shot. 2 hours + of this makes for a fun night

[@juansolo9166]

Just a 10 minute video would black me out 😂. Now with a 2 hour vid I would certainly die of alcohol poisoning

[@DaBlaccGhost]

Do coke instead, alcohol inhibits protein synthesis in torn muscle fibers

[@Will-uf9nd]

awesome video. like most of your videos, it makes me not really want to mess with my hpta at all

[@orbitals5281]

Got mine today ordering the day when the video dropped. I'll update this in a month after using it with results.

[@degeneratechris]

I've been taking tongkat and ashwagandha for about 6 months with no negative effects so far. Noticed some decent gains and libido is strong. I have yet to get an up to date blood test, but plan to get one very soon and I'll revisit this post to compare my last blood to new one.

[@Jordan-vl4lj]

Have you gotten any leaner since taking them?

[@degeneratechris]

@@Jordan-vl4lj actually, yes, even though I've been bulking and maingaining, I'm slightly leaner than I was before taking this 'stack'

[@Jordan-vl4lj]

@@degeneratechris Damn that's good. I'd heard that the stack can make people leaner and that's what's really appealing to me and making me wanna try it. thanks for the response man

[@elmeracosta8250]

It took me like 6 hrs to finish this video, since I had to google so much stuff!!! 😂 Thanks! Very helpful!

[@JD-cg1nl]

Such a comprehensive video, what a legend

[@michamatysiak6436]

These table of contents..... excellent fabolous ❤ keep it up

[@liammcleod159]

At this point I would appreciate episodes like these uploaded to Spotify. Would be a lot easier to listen while running or working out than through yt

[@jessen_0124]

They are on Spotify. Usually doesn't hit Spotify until several hours after it's on YT but it'll be on there.

[@KingSwoleNerd]

Why can't you listen to this while running ?

[@liammcleod159]

@@KingSwoleNerd run with a Garmin watch. Can't play yt. Can play spotify

[@imwachos8490]

@@jessen_0124 what about Apple podcasts

[@KingSwoleNerd]

@@liammcleod159 oh, ya didn't think of that.

[@JayP7.62]

I’m on day 6 of taking Sigma, 4 capsules a day and I’m starting to feel it. 3 weeks before I started taking it I started taking zinc, D&D3, and magnesium supplements. Plus taking citrulline, fish oil and coq10. So all those supplements may have helped also. Oh and I was drinking 5 or 6 days a week and quit two weeks ago. I haven’t been in the gym in like 17 years and I’ve been on methadone for 16 years. I didn’t get any bloodwork done but I have all the symptoms of low testosterone. On average men on methadone have 1/4 the testosterone levels as man the same age not on it. I’m 41 and didn’t want to start TRT just yet. Right now my financial situation isn’t the best and there would be no guarantee I could afford to stick with TRT consistently. So I started doing research and found Sigma after finding out about the two main ingredients. I’m starting to feel great and actually have motivation to do activities. Usually I would be struggling to do anything and would have to push myself. I actually feel motivated to work out. Unfortunately I have an umbilical hernia I got after gaining weight and getting my beer belly. So I can’t lift heavy weights but I will try to do what I can until I have surgery. I’m only on day 6 and can’t wait to see how much better I feel after a few weeks. I’m really glad I started looking into the effects of methadone and what I could do to help my testosterone level. If anyone is suffering from low testosterone levels Sigma may help you.

[@padraics]

After 16 years I think you'd be good to switch over to bupe. From what I've seen, studies show it has little to no impact on T compared with methadone

[@JayP7.62]

@@padraics Why would I switch to buprenorphine after this long on methadone? Even if I did you can’t just switch. You basically have to have all the methadone build up from years out your system to be able to take buprenorphine. You can’t mix the two. It puts you in instant withdrawal symptoms. Been there. If I’m gonna make that big a commitment to stay home and not be able to go to work from withdrawal I’ll take a little more time off and quit. I’m gonna save up to get off with ibogaine.

[@mexicanchinese]

Bought it and waiting for mine!

[@abraman41]

Amazing video! Quick comment on the use of "blue blockers" at night, to the extent of my knowledge, blocking blue light at night does not have any specific health benefits rather than just blocking any light out.

[@pauliedontsurf]

Derek showed a gorilla bottle with sigma written on it and 93 seconds later I had two purchased and on a fedex priority shipment to Europe. Let’s. Go.

[@Barz4Dice]

Do we have to pay import tax on top of the expensive shipping in Europe?

[@pauliedontsurf]

@@Barz4Dice let you know in a couple days man.

[@PrimeDiam]

@@pauliedontsurf😢

[@zehaha111]

So could you take this in combination with ecdysterone and/or turkesterone? Would be interesting if these products can be combined without major risks for your health.

[@tristanyokom1542]

@Based Ohio The cortisol blocker is amazing, though I don't take it every night