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Referinte:
Autophagy:
Medicine Nobel for research on how cells 'eat themselves’: www.nature.com/news/medicine-...
theartofmed.wordpress.com/201...
Alirezaei, M., Kemball, C., Flynn, C., Wood, M., Whitton, J. and Kiosses, W. (2010). Short-term fasting induces profound neuronal autophagy. Autophagy, 6(6), pp.702-710.
Ming Hu, Zhijuan Liu, Peiyuan Lv, Hebo Wang, Yifei Zhu, Qianqian Qi, Jing Xu, Lei Gao. (2017) Nimodipine activates neuroprotective signaling events and inactivates autophages in the VCID rat hippocampus. Neurological Research 39:10, pages 904-909.
Tae Seok Oh, Hanchae Cho, Jae Hyun Cho, Seong-Woon Yu, Eun-Kyoung Kim. (2016) Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression. Autophagy 12:11, pages 2009-2025.
Kenta Kuramoto, Nan Wang, Yuying Fan, Weiran Zhang, Frank J. Schoenen, Kevin J. Frankowski, Juan Marugan, Yifa Zhou, Sui Huang, Congcong He. (2016) Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy 12:9, pages 1460-1471.
Congcong He, Rhea Sumpter, Jr.Beth Levine. (2012) Exercise induces autophagy in peripheral tissues and in the brain. Autophagy 8:10, pages 1548-1551.
Brain Neuroprotective:
Mattson, M. (2012). Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease. Cell Metabolism, 16(6), pp.706-722.
Halagappa, V., Guo, Z., Pearson, M., Matsuoka, Y., Cutler, R., LaFerla, F. and Mattson, M. (2007). Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiology of Disease, 26(1), pp.212-220.
Cardiovascular Health:
Longo, V. and Mattson, M. (2014). Fasting: Molecular Mechanisms and Clinical Applications. Cell Metabolism, 19(2), pp.181-192.
Cancer Prevention and treatment:
Raffaghello, L., Lee, C., Safdie, F., Wei, M., Madia, F., Bianchi, G. and Longo, V. (2008). Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proceedings of the National Academy of Sciences, 105(24), pp.8215-8220.
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