Regulatory T cells

This video describes a detailed mechanism of action of regulatory T cell and also describes the genetic and epigenetic basis of Treg lineage specification.

[@diepnguyen-xg7yn]

Wonderful explanation. You have a gift of explaining hard to understand concepts nicely! Thank you!

[@animatedbiologywitharpan]

Please share my channel link with your friends and help me to reach big audience

[@animatedbiologywitharpan]

Don't forget to check out my entire immunology playlist

[@carmelinabocchino1297]

Just what I needed right now! Thank you so much!

[@animatedbiologywitharpan]

Please share my channel link with your friends and help me to reach big audience.

[@animatedbiologywitharpan]

Dont forget to check out my immunology playlist for all the concepts in immunology

[@nivodejayathilake5196]

This is so helpful. Thank you for this video. This helped me a lot today. I like your teaching skills.

[@animatedbiologywitharpan]

In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

[@dr.germandelagarza6400]

This totally came from, Dr Cepika MD articule on Tregophaties, thank you very much for the explanation very helpfull for the inmunologist community

[@animatedbiologywitharpan]

Thanks, glad to see that you liked it

[@goranbras4767]

Bravo ,kratko ,jasno i efikasno !

[@animatedbiologywitharpan]

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

[@shifasaleem6697]

Cd8 population also inhibited by same tregs or any other different mechanism .? Please upload Bregs too.thankyou

[@srijandey87]

Again a clear cut explanation saved my time

[@animatedbiologywitharpan]

Please share my channel link with your friends and help me to reach big audience.

[@srijandey87]

@@animatedbiologywitharpan sure

[@proxythinkeraccountnumberone]

Sir, what happens when Tregs supress APC Or Macrophages inflammatory response? Does the Macrophage become unable to signal Th2 cells and that way allergies stop happening?

[@dr.sagarsingh5723]

Thank you, Video helped me in clearing confusion, it means that CD25 which is Receptor of IL2, so this CD25 is present over both Treg and CD4 T cell, and so Treg CD25 competes with CD25 of CD4 cell so that IL2 doesn't act on CD4, so CD4 doesn't get activated, Is my thought process right?

[@jojon185]

Very good explanation, well done and thank you.

[@animatedbiologywitharpan]

Don’t forget to check my immuno playlist...might be useful for you

[@animatedbiologywitharpan]

If you like the video please share among your friends and help me to reach big audience

[@vosserr]

Very helpful, thanks!

[@animatedbiologywitharpan]

Glad to know that it helped....share among friends and help them as well

[@lua-wz8yf]

saved my presentation today, thank you so much

[@animatedbiologywitharpan]

Please share my channel link with your friends. Also you can pay us money ( only 10$) to cistomize your presentation. Feel free to connect via email any time.

[@andrewfoers8861]

Nice explanation. Thanks.

[@animatedbiologywitharpan]

Andrew Foers don’t forget to check out other videos in the playlist .....please share among friends and help me to reach big audience

[@gamergamex.9892]

Very helpful, thank you

[@animatedbiologywitharpan]

Please share my channel link with your friends and help me to reach big audience

[@fmh654]

what about TGF-β

[@CwdenShorts]

CD4+ T cells become Helper T cells because CD8+ co-receptor is down regulated (1:55). Those with CD8+ co-receptor are found on cytotoxic T cells or natural killer T cells.

[@animatedbiologywitharpan]

Yes cd8+ coreceptor is characteristic to cytotoxic t cells

[@__Wanderer]

Very interesting! Do you know if there are ways/research to increase Treg cells? Would be great if you could try to boost these to reduce inflammation / improve autoimmune response.

[@animatedbiologywitharpan]

Yes there are ways , may be i should make a video on that

[@animatedbiologywitharpan]

Read this article to know more www.nature.com/articles/s41577-019-0232-6

[@__Wanderer]

@@animatedbiologywitharpan amazing thank you for the link and your reply! :) Definitely a fascinating topic - personally was diagnosed with MS 3 weeks ago and am looking for ways to biohack my body a little / stop it attacking itself besides the treatment I will likely start soon

[@gregorbrammi9885]

sir super explanation do more videos of immunology at molecular and genetical level. than you vey much sir

[@animatedbiologywitharpan]

Check out my immunology playlist .....I think it covers quote a lot of topics

[@gregorbrammi9885]

@@animatedbiologywitharpan 🙏🙏🙏

[@yasirquershi3070]

Brother, which software u use to get these figures and animations....

[@animatedbiologywitharpan]

Microsoft PowerPoint only

[@yasirquershi3070]

@@animatedbiologywitharpan bdw gentleman u r a lier...

[@animatedbiologywitharpan]

@@yasirquershi3070 why?

[@user-hj3jb4qn2n]

Thank you for excellent lecture. I have one question The question appears on test in Korea. What is the biomarker of Treg cell and is related to IL-2 receptor? 1.CD4 2.CD19 3.CD25 4.FoxP3 5.GATA3 I think there are two answers(both 3&4) Can you choose one?

[@animatedbiologywitharpan]

Foxp3 is a good marker of Tregs especially if panels of markers were used for their identification. T REG Cells will be CD4(+)CD25(high) Foxp3(+) . CD25 alone is not a very specific marker.

[@user-hj3jb4qn2n]

Wow, thank you very much😊 Can I ask your career?

[@tanushreesarkar6627]

thnx a lot...😌

[@animatedbiologywitharpan]

Tanushree sarkar glad it helped ......share among friends and help them as well

[@aynalsaba7982]

It's really helpful....can you please make a video on foxp3 role in immunological pathways of recurrent pregnancy loss.

[@animatedbiologywitharpan]

aynal saba please share my playlists with friends and help me to reach my audience

[@aynalsaba7982]

Ya sure.

[@meryamlazrak1329]

Thank you sir

[@animatedbiologywitharpan]

Please share my channel link with your friends. Stay tuned

[@subinbyclema]

IL-2 compete IL-10autoimmune disorder delayed anti-inflammatory response

[@dhananjayamuthurayappa674]

Do video on regulations of t-cell and bcell response

[@animatedbiologywitharpan]

Check out the immunology playlist and you would find it....

[@samanthagonah8243]

i think regulatory t cells can have either CD8 or CD4 receptors.

[@animatedbiologywitharpan]

As far as I know treg cells are subclass of cd4 t cells......I would check the current literature and let you know......thanks for raising the point

[@samanthagonah8243]

@@animatedbiologywitharpan yeah I have seen it in some articles. I will also try do further research. great video though!!

[@animatedbiologywitharpan]

Glad you liked it.....please share in your community such that I can reach out more people

[@TheDBZgamer]

bro if its ok...can i get ur ppt file or pdf file...i need this for my thesis...and ofcourse i will credit you and also label your name under reference...

[@l.k.gdancers4325]

What is ur topic for ur thesis

[@leroy44]

1:53 "CD4 positive T cells" not "CD8"

[@animatedbiologywitharpan]

Yes noted.... small mispronunciation.... thanks for pointing out

[@ghassanauf8103]

thank you lerony