What Every Woman MUST KNOW to PREVENT Alzheimer’s | Neuroscientist Lisa Mosconi X Rich Roll Podcast

Rich sits down with neuroscientist Dr. Lisa Mosconi to discuss menopause and brain health, Alzheimer’s and dementia, neuro-nutrition, hormone replacement therapy, and much more. To read more about Dr. Mosconi and peruse the full show notes, go here👉🏾bit.ly/richroll819
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FILMED AND EDITED BY BLAKE CURTIS, DAN DRAKE AND MORGAN MCRAE
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TIMESTAMPS
00:00:00 Intro
00:01:15 Dr. Mosconi's Background
00:03:34 Interest in Neuroscience
00:04:37 Move to the United States
00:06:14 Gender Disparities in Alzheimer's
00:08:27 Historical Context of Women's Health in Science
00:15:16 Bikini Medicine
00:19:16 Sex Differences in Brain Aging
00:22:46 Understanding Menopause
00:23:57 Impact of Menopause on the Brain
00:25:36 Research Gap in Menopause and Brain Imaging
00:26:34 Brain Scans and Menopausal Status
00:29:17 Genetic Predisposition to Alzheimer's
00:31:57 Sponsor Break
00:33:05 Back To Show
00:34:31 Apolipoprotein E (APOE) Gene
00:38:28 Menopause and Cognitive Changes
00:49:16 Evolutionary Perspective on Menopause
00:49:35 Brain Scans and Menopausal Changes
00:53:43 Menopause and Brain Changes
00:55:47 Differential Menopausal Experiences
00:56:13 Menopause Types and Health Risks
00:58:02 Hysterectomy and Alzheimer's Risk
00:58:47 Induced Menopause and Cancer Treatments
00:59:52 Understanding Alzheimer's and Dementia
01:02:06 Sponsor Break
01:03:13 Cardiovascular Health and Dementia
01:05:55 Lifestyle and Brain Health
01:11:53 Neuro-Nutrition and Brain Health
01:17:30 Antioxidant-Rich Foods
01:19:35 Supplementation and Nutritional Deficiencies
01:21:57 Antioxidants and Brain Health
01:23:02 Fiber and Hormonal Health
01:24:05 Microbiome and Hormonal Health
01:27:47 Exercise Intensity and Brain Health
01:32:11 Consistency and Long-Term Impact of Lifestyle Changes
01:36:05 Hormone Replacement Therapy and Alzheimer's Risk
01:45:07 Hormone Replacement Therapy
01:46:30 Estrogen Only Formulations
01:49:28 Timing and Type of Hormone Therapy
01:50:26 Brain Scans and Designer Estrogen
01:54:20 Pharmacological Interventions
01:55:41 Diet and Menopause
01:57:10 Sleep and Brain Health
02:06:18 Baseline Testing
02:11:15 Brain Scans and Alzheimer's Prevention Program
02:15:12 Media's Relationship to Health Information
02:16:16 Social Media and Information Accuracy
02:22:08 Scientists and Doctors' Communication Challenges
02:23:22 Science Communication and Public Understanding
02:23:59 Closing Remarks/Credits
* * * * *
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[@richroll]

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[@georgiehughes4858]

So extremely interesting & significant!! I’m a grandmother sharing this video with my daughter & daughters-in-law

[@theredboneking]

Among developed countries, Japan has the lowest prevalence of both dementia in general and Alzheimer's disease in particular. Look up in the sky, Japan has virtually no white lines in the sky, caused by airplanes ✈️

[@monicatata6725]

Long moment of beautiful conversation, so as a Women (XX Chromosomes) with a Invasiv Ductal hormonal Carcinoma at age 32, went along with all the *treatments recommendations Neo adjuvant Chemotherapy + Radiotherapy + Herceptin + Radical Mastectomy personally I drew the line at Tamoxifen therapy, the point being all throughout those first 3-4 years, I did what I was told by Doctors, who assumed knew more about my body wellbeing than I did, maybe due to menopausal Brain changes 😂, when I started to do what I felt was right for me, I earned more quality health & wellbeing & curiously *regain menstruation cycles after being diagnosed with Menopause (that lasted for 3 years) as an adverse consequence of the Neoadjuvant Chemotherapy protocol. In conclusion One cannot be an expert on Health when there are so many variables in Every Human Being

[@jacquelinehoffrealestate]

Wow...an incredibly informative interview! Thank you!!!

[@junyfulton4406]

Hi I am curious about IVF connection with Alzheimers . Any research or information about it?

[@k.h.6991]

If you get depressed watching this, skip to the end where Lisa discusses what we can do with exercise, diet and sleep to improve brain health and lighten the impact of menopause.

[@lynnritchie231]

It is quite depressing tbh.

[@christinanewdeck5417]

TY for the heads up! I look at comments before watching . . and this helps ~ I'll watch this later!

[@normahade9856]

Thank you❤

[@janenls1066]

She sounds a nice and sincere lady but this just all sounds very depressing.

[@SculptExpress-gv8jp]

Witnessing my parents and my friends’ parents decay was truly depressing; maybe that’s childish, but I was not prepared for it although I went through if with my grandparents who I loved very much, but I was younger then. Now, with my parents, other family, friends’ parents and witnessing some old friends passing, I started feeling the death for the first time. That said, I am actually comforted to hear the scientific explanation of our aging and what’s going on with our brain and how we can try to slow it down. My mother ate super healthy, home cooked farm stuff, but once she developed dementia, all she wanted was sweets.

[@jenniferrourk6403]

This should have thousands of likes! This is the best interview I think I have ever seen on KZbin. It matters to everyone not just women of a certain age. Thank you for doing this interview.

[@Lil33bit]

I agree. I made a point to go back and like it.

[@victoriamartinez8783]

Her book ‘The XX Brain,’ is a MUST read!

[@leahculberson3665]

Agree. Thank you, Rich Roll!

[@CarolGasses]

I’m hoping for millions of likes!

[@portalsandpathways]

I’ve been sharing with my family and friends

[@jenniferflaherty730]

I noticed with my Mom, that when she didnt get enough oxygen (ie: move her body to breathe more), her mind would be foggy. I caught on, and would ask her "did you walk the hallway today, Mom?" If she said "no", then I watched the conversation be dull and flat. When she said "yes!", we had a normal, spirited conversation. I'm glad I noticed that connection, as Im 100% convinced that keeping in motion is the KEY to brain health.

[@Xica448]

This is also my impression

[@juliesczesny90]

YES!!

[@SculptExpress-gv8jp]

Once my granddad stopped walking to the fresh food market, abt 15 min walk + shopping and return (he did it almost daily), he said that his life was over. And true enough, about two years later he died. He was in his mid 80s, smoked two packs a day, survived tuberculosis, poverty, world wars, drank alcohol more than water, but walking was his test of good health. As a young and mid aged man he walked for miles and miles and in his 80s was to the market. Well, the research shows now that walking and carrying weight as in shopping bags have enormous health benefits. My father walked the same way, but did not drink much and never put a cigarette to his mouth. He died a year earlier in his 80s from his father. And the end came about the year after he couldn’t walk well anymore. Why he suddenly became weak to walk, I don’t know because he wasn’t physically ill, but mentally he became very depressed.

[@jenniferflaherty730]

@Sculptexpress: exactly to your point, my Mom also shared with me that the worst thing she did was to hire a weekly cleaning lady. She never lifted heavy furniture or pushed a heavy vacuum cleaner again. She told me she was proud at the time to be able to afford a cleaning lady, but then 25 yrs later she realized that was the start of her physical decline.

[@eileenwatt8283]

​@@SculptExpress-gv8jptrue Alzheimers is seldom seen in countries where people walk and have more of an out door life styles. It's less prevalent in Africa. Asia and third world countries.

[@kare5252]

As a life long runner 🏃 I noticed that through menopause my strength drastically reduced and injury and joint problems increased very depressing but I moved to weights, strength/ resistance training and it was life changing

[@carolinedelosso6429]

Yes! I had to take time off for an injury but lifting weights and some running with mostly walking works for me. I am also a life long runner and I had to pivot and learn that strength training is essential

[@Mariaharris143]

So you don’t run anymore? I’m 46 and actually ran my first 1/2 marathon two weeks ago. I’ve been doing yoga and other excercise majority of my life.

[@PoetOnTheRun]

Ultra runner for years. Now in 50s and need to diversify - yoga HIIT dance and weights

[@lenasimpson8016]

Nordic walking is a good alternative to running for some people.

[@Elena-fe3os]

@@Mariaharris143 As we age , the degradation of the body is accelerating . The bone density, the muscle mass go low, is increasing the risk for many illnesses and many do not think about any of this, till have health issues. I also quit running , my joints are overused. Stretching is part of my life , weights lifting helped to build muscle mass and lose weight. I still walk , eat more meat. I feel stronger than years back . I believe that middle aged women..and older, should be more informed about menopause, more present at the gyms, to lift weights, as much as their health allows them to..keeping muscle mass becomes more important

[@charliewilliams3826]

What I love about this doctor is how she refers to the research as EVER EVOLVING, points out weaknesses in the research she has studied, and ongoingly speaks in terms of "what we know thus far" rather than treating science as ABSOLUTE or DEFINITIVE. Anyone properly trained in research knows that you can verify or falsify a theory but there are no HARD TRUTHS in science. The last few years there has been a great deal of misunderstanding and a lack of scientific humility among well known top doctors. I find hope, anew, in the wonder and promise of doing systematic research using strong methods that can be replicated and build upon the body of knowledge we current have at our disposal. Thank you so much for doing this interview! Never heard of either of you - just happened to stumble across this video! It feels like a God-sent so THANK YOU SO MUCH ❤

[@vtheb1299]

You are so right but unfortunately the sane and reasonable stance doesn't "sell" as well as polarized extreme views on social media... Or politics! 😢

[@bienerbina4555]

Agreed!! I also "stumbled" on this Podcast and I'm so glad I did. The podcast Diary of a CEO also did a great interview regarding menopause & hormones which I also recommend you watch. I'm 65, and when going through menopause it was determined that HRT put women at risk for heart problems & we were denied HRT. So many of us went through years being miserable when we didn't need to be. I'm just thankful that the mindset is being changed regarding women's health. Of course, this is likely bc it is women Dr's & researchers who are now speaking out as opposed to mainly men making decisions for a woman's health concerns.

[@MoneyStrategiesSOULutions]

Indeed

[@reneecaines9097]

Agreed. Integrity in science and science education is deeply important.

[@Bella34544]

Such an important conversation. I work in disability and mental health and a good percentage of the people I work with are woman diagnosed with early onset dementia that is my clients anyway have all been diagnosed in their early 50s. I tell you categorically there is no diagnosis more cruel than an early onset dementia diagnosis and also when diagnosed early the progression tends to be a lot faster - it's absolutely devastating for everyone. Now what for many woman also generally happens in their early 50s? Menopause. The lack of research in this area is just blatant misogyny and sexism. Thank you both for having such an important conversation

[@chandrakasakevich4657]

That's my mom.

[@debbiedebbie9473]

Are they approved for disability with dementia ?

[@irenedoyle3421]

A tablespoon of organic Extra virgin Coconut oil before every meal will feed the brain, the brain needs healthy fats to function properly, if the brain is starved of healthy fats, dementia sets in, also lions mane mushroom supplements will clear the brain fog and repair neuro transmitters in the brain

[@irenedoyle3421]

Also if the dementia sufferer is on statins for high cholesterol, get them off it, cholesterol is not bad and one of the biggest frauds in medical history, low fat diets and cholesterol medicine are what causes dementia, the brain is made of cholesterol and needs more to stay healthy, once off the statins and low fat diet the brain will start to function normally within a couple of days

[@uqox]

This month-old podcast has less than a million views, which is an example of how research and scientific studies on women's health are squeezed out of social media. Here's what I'm going to do: I'm going to forward this video to *every woman I know*, share it in my social circle, and encourage them to share this podcast in their extended social circles. *Women are in desperate need of these types of in-depth discussions.*

[@WahidaJoosub]

I hate to say this but how much compensation has Lisa Mosconi received from big pharma? I say this because 30 years ago my mom took an all natural product called Wild yam cream -WYC to deal with her menopause issues . Not only did it help her with those issues. Fast forward, my mom lived to age 87 with no complications of dementia, breast cancer or brittle bones. Note my mom was on the WYC for six years. My mom is one out of nine sisters and 6 of her younger sisters ended up with dementia, they were not on the WYC. The only medication my mom required from age 48 to 87 was thyroxine. Lastly my mom never really exercised throughout her life but she cooked almost everyday of her life, enjoyed listening to podcasts, stayed in touch with family overseas by Skype and was always surrounded by people who loved her. Ultimately the WYC has worked for so many women as it's all natural and relatively cheap. Yet few people know about WYC. Could it be because big pharma won't make money. We are of nature so why do we need something not of nature to feel and be healthier????

[@dessaarnold7540]

It always needs to be asked.

[@melodybrooke1376]

Modern HRT is plant based bio identical estrogen

[@gaildhw7070]

Thank you for sharing this❤

[@kt9495]

This is the 2nd time this week I’ve heard about Wild Yam Cream. Thanks for sharing your story. 💛

[@jillmahal4695]

She is NIH funded. So, very good question. Also, Black Cohosh did wonders for my menopause symptoms.

[@sidilicious11]

I’m so glad Dr Lisa and others are doing research into woman’s health. Much more is needed. Eat yr fruits and veggies, sisters!

[@potterylady44]

Omg yes!

[@nanskiboutski243]

And DANCE! And stop caring what (you think)people think about you, FFS!!

[@tonee.1012]

The day I stopped fruit and vegetables my horrible symptoms disappeared.

[@sidilicious11]

@@tonee.1012 I’m sorry fruits and veggies didn’t work for you. I’m glad you feel better.

[@VickiNikolaidis]

I wonder about the impact of misogynism on the brain.

[@vhs10907]

"I'm a scientist and opinion does not matter to me, but numbers do." This statement by Dr Mosconi says so much about listening to her knowledge of what science says. She is a person to listen to.

[@LenkaSaratoga]

Excellent quote 💚👍 If not a bother, can you please add time stamp when she says it?

[@vhs10907]

Thank you for asking! I should have entered the time stamp. She says that at 1:37.00. (I tried to make this a link but was unsuccessful. Even though it is blue, it does not go to 1:37 for the quote.)@@LenkaSaratoga

[@LenkaSaratoga]

@@vhs10907thank you for responding 1:37:00

[@jenniferleibig1901]

I enjoyed this video. I started perimenopause at 54. I changed my diet in a very radical way. I flipped to a ketogenic diet. Radical keto. Less than 20 grams of carbs a day. Increased saturated fat. Fat is my fuel. I have reversed the weight gain. Lost it off my midsection. Hot flashes are barely noticeable. Mental acuity is back. Sleeping better. Periods are back. I don’t understand all the connections but when I make sure that I have the fat I need and quality meat, everything in my body celebrates my choices. Cholesterol isn’t something that I need to worry about now. Sugar is my enemy. In all forms. I am thrilled that these issues are coming to light. Each woman needs to find their sweet spot. Some do great on a more veggie based diet. Some do not.

[@waffle_chair9269]

I’ve heard of keto brining back periods and clarity for women before. I really think there is something to it, and I think it’s from the microbiome, making the neurotransmitters in the gut, that then effects the brain, as a result of low carbs, hence keto. Keto was originally for epileptic kids. So it all makes sense and ties in together.

[@MoneyStrategiesSOULutions]

I had to go all the way carnivore to heal it. Tried with veggies and hundreds of dollars on natural supplements every month to no avail. LDL nourishes hormones!

[@Blonde111]

Hmmm, I don’t think you actually listened to her at all regarding fat intake.

[@gilly5094]

High fat diet is not good for the heart. There is increasing evidence against Keto for this reason. I agree that lowering carbs is important. Most important is cutting out sugar completely. I don’t believe that veggie diet is good over 50. I used to be pescatarian but re-introduced meat because I felt I wasn’t getting good quality protein. I feel much better after adding some meat to my diet. Best thing you can do to protect against Alzheimer’s is to go on body identical HRT.

[@dianamariewells1437]

Healthy Keto is healthy fat, your brain is fat, hormones are cholesterol, fat is life. Mid 50s, regular cycle, no menopause symptoms. Sugar is deadly, it's a fact. It causes blindness, death, it's very linked to dementia too... Doubtless it effects our sensitive reproductive systems. Makes more sense than fat doesn't it? Gluconeogenesis, your liver makes all the sugar (1-2 tsps) your body needs. Sugar is subsided by the US government. $$$. Sugar is poisonous in large or continuous amounts. It hurts women more than men but it kills us all. Pretty sure it causes menopause too.

[@kali542]

I experienced menopause at age 43. I experienced psychosis. I was treated as a psych patient until I demanded estrogen (docs glad to give me lithium but declined over & over to give me HRT). Two days on estrogen patch cured me. I’m 58 now still happy & healthy on estrogen. I have two older sisters who are fully disabled with mental illness and addiction post menopause. They don’t take HRT. The are both forgetting a lot, spell words wrong and have trouble regulating emotions.

[@lindajones4849]

Good for you for demanding estrogen especially when having mental health issues . I'm surprised you got a traditional doctor to pay attention to you.

[@Himmiefan]

There's a problem with this mentality that the body is malfunctioning when it goes into menopause, that it will automatically decline, and that taking medication is the only way to fix it. Those hormones change over time for a reason, and we must first talk about the bad effects of the Western diet on the post-menopause body. Women in the East don't have most of these symptoms until they eat a Western diet.

[@laurapiovan]

What is HRT? How do one gets prescriptions for estrogen ?

[@kali542]

hormone replacement therapy the best place to start is with your obgyn @@laurapiovan

[@bamanana2922]

@@laurapiovanHormone Replacement Therapy

[@zoecoote3746]

We need to ask ourselves why so little research has been done in this area seeing as it effects half the population. What a brilliant woman and scientist. She will truely change lives and hopefully change the trajectory of research in women’s health.

[@justbeegreen]

Because women haven’t mattered in health care industries.

[@MastiffHeart]

Theres's no money in the cure of any disease . Money is made off human suffering

[@MastiffHeart]

There is no money in the cure of any disease. Millions are made off of our suffering.

[@LuciThomasHardylover-qx6ts]

My g.p. practice has five male doctors and one female. Not a single male doctor will discuss,birth control,periods, genitourinary issues or menopause!!!! In 2024!!! We all have to see the lady doctor 🤦 Isn't it amazing! In this day and age! That's half their patients and most of their problems.

[@justbeegreen]

@@LuciThomasHardylover-qx6ts that’s ridiculous!

[@EllenMDallasgirl]

My mother was diagnosed with Alzheimers at age 59. She died 10 years later.Her neurologist said she did not have the gene for it but that I should make sure I keep a check on my estrogen as I age. I’m 63 now, on HRT, have always exercised and eat clean.

[@lindalamb7512]

EllenMDall- how did dr determine that and can you tell us more about Hrt?

[@juditrotter5176]

I’ve been using bio identical hormones, estradiol.

[@EllenMDallasgirl]

@@lindalamb7512 My mother’s neurologist did bloodwork to look for my mothers genetics. Note: Alzheimer’s Association says that 90% of those diagnosed don’t even have a gene. My take away on that is that lifestyle and replacing what’s loss is key. My HRT journey has been long with many ups and downs. Even with that, I believe I’m better off by taking them. At this time, I’m on time released, compounded estrogen and progesterone. Until a few months ago I didn’t know that was available. My last provider of 15 years didn’t always keep me balanced properly. They’ve come a long way in helping women and I believe it will continue to get better. When I first had hormone issues all my doctor could offer was birth control pill or anti-depressants. I’ve come a long way too! I still have to do my part and make good choices with my health.

[@firefeethok_tui2355]

@@lindalamb7512HRT is “hormone replacement therapy” (estrogen and medroxyprogesterone) ….should be started in perimenopause if youre a candidate. (Doctor determines your risk factors such as BRCA gene etc) I dont know if it can be started after menopause has already commenced (those were the faulty studies on HRT in the 1970-80s or whenever it was). After that almost no major researchers literally cared about womens health again. (Seemed that way) Its now getting some much needed attention.

[@GlamGail]

@@juditrotter5176hi where do you purchase your meds from?

[@marialourens8057]

At last! A woman speaking on menopause and Alzheimers. Thank you so very much for this great interview, I subscribed immediately, which I don't really care about in post-menopause!

[@kelseyloushin1343]

It's about time someone brought this critical information to men & women! Thank you, Rich for this incredibly important program! I can't begin to tell you how often I have this conversation with my female friends. The medical community is so deficient in addressing this. One of the best things I did for my brain was to use estrogen. I immediately noticed cognitive improvement! Omega 3's should be a required supplement for everyone! Along with so many other things. Sorry to get on my soapbox! Thank you!

[@user-cu2bj7bl5q]

Your soapbox is perfectly constructed! Climb up ANYTIME!!!

[@keepingitreal618]

I presume that’s all researched based so direct us to the studies

[@yaditube1976]

How did you get that?

[@kellio8087]

Menopause and chronic stress caused me autoimmune disease. My body and brain was going down quick. Doctors didnt help so I did extensive research and chose to do an anti-inflammatory diet, supplementation, and stress elimination. That worked for me.

[@ruth6511]

I am of the generation that were affected by the WHO study so got no HRT and now at 65 it is too late as I am 15 years out from menopause. I am glad for younger women, but sad for my generation that got no help.

[@pejisan]

yup. i'm enraged at the sloppy data science that left us both high and dry...medicine owes us some answers and HELP. I think I'll just start on HRT at 70

[@pejisan]

also, i can't sleep! all this talk of how critical sleep is also stresses me out! damn the WHI

[@rachelsavard851]

I've just started the video because i defintely think menopause caused troubles in my brain. and ironically i just asked a doctor to try HRT but he said it was 'too late' as i'm about five years in .

[@sarahoward6745]

No!!!! Get a second opinion and don’t give up! Follow: Dr MarieClaire Haver and Dr Sara Gottfried, who are amazing doctors who mainly discuss and specialize on menopause and its effects and symptoms of it and how HRT can be very beneficial! They also have touched on how it’s not too late to start the therapy, especially if you’re still on your 50’s. HRT therapy can be a lifesaver in so many ways for us women going through Menopause. Blessings and Good Luck!🙏🏼

[@peacefulheart1431]

I started late with plant based HRT & still see improvement in skin and hair. I also noticed that the brain fog decreased. I am currently working on deep sleep. It's never too late. Just pay attention to what your body prefers.

[@dianebutchart9049]

Well I'm 75 and look 60. I swim and golf regularly. I'm a meditator eat one meal a day plus 2 healthy snacks plus vitamins. I've taken also natural HRT for over 35yrs!! I feel great look great and am always have interest in many things. I sell realestate am learning Spanish and the list goes on!!! I give thanks daily.!!!❤❤

[@keepingitreal618]

My mother was the same looked much younger, never stopped she developed alzheimers at 80

[@farmthreads5679]

What is natural hrt

[@mlfmlf8755]

What is natural HRT?❤

[@carolinedelosso6429]

Yes what do you take as a natural hrt supplement??

[@tarakennedy3041]

My aunt walked her whole life. Ate healthy and learned a new language at 65. She also died of AD at 82. I wish there was an actual plan for each of us. But men will not allow it. 😮

[@nikileach]

Menopause totally destroyed my life cause I had no idea what was happening to me! Listening to these kinds of podcasts with Dr Lisa, Dr Louise Newson and Dr Claire I've managed to understand the effect this has had on me and to get the right help!

[@darrisnelson5223]

This is such an important conversation… Thank you Rich for hosting Lisa. I will read her latest book book, “The Menopause Brain”. My mom was never formally diagnosed with dementia. She had symptoms for years that went either unnoticed, or ignored by Western medical doctors. She was on HRT for several years of her life. She died at 89 with late stage dementia and squamous cell carcinoma. The squamous cell carcinoma went unnoticed and untreated for several months. Because of her dementia, she was unable to articulate what was going on with her body and my stepdad honored her wishes not to go to the doctor. My sister and I got involved after an emergency trip to the hospital forced my stepdad to include us, it was far too late. Without getting into any gory details. My mom’s cancer wound was necrotic. Watching a vibrant human being who had always been active and engaged and worked well into her 70s deteriorate mentally with heart wrenching. It’s been a little over three years and it still haunts me. I am 68 and I’ve never been on HRT. I have been vegan for 20 years, vegetarian years before. 20+ years ago all we were offered was Premarin which I would never consider taking for ethical reasons. Menopause went very smoothly for me so I felt I had no reason for HRT. it was my understanding it’s too late at my age for any hormone supplementation to have any effect. I’m anxious to understand more and hope that Dr. Lisa‘s book answers some questions before my doctor appointment (first Western medical doctor appointment in 20 years) next week. I would have loved Julie being included in this Episode,. My guess is she would have had great questions and a lot to offer and add to this conversation. Thanks so much Rich for always keeping us on top of the latest quality information!

[@agnes77741]

Dear all, I will be 64 next month. Periods stopped at the age of 48. Had hot flashes etc. but it did not bother me till a few months ago. Hot flashes are suddenly making me like fainting, frequent UTI symptoms (pain!) since 3 years, insomnia increased. Decided to ask for HRT last week and started yesterday evening. It is 4 pm now and usually I would have had 10 hot flashes since morning. I had only TWO. Cannot believe it. Life is worth living again.

[@sabinadonofrio8863]

Stop eating sugars and breads, all sodas!! Give it two weeks

[@LadyBug1967]

Agnes, I did not know that they could return? Is the pain constant or only with sex? Did u get any COVID vaccines? If so, do get checked by a doctor cuz very serious changes have been caused by this vaccine and the pain and flashes could be a symptom of something more serious. Is your HRT bio hormone replacement or chemical?

[@agnes77741]

@@sabinadonofrio8863I stopped bread 2 years ago and there´s not much sugar in my diet. Never had a soda in my life. Thanks!

[@agnes77741]

@@LadyBug1967 I have hot flashes since the periods stopped in 2008. My mother had hot flashes till her death at the age of 78. I got Covid vaccines and they are not the cause for low estrogen levels. I got checked by a great doctor. Thanks.

[@agnes77741]

@@sabinadonofrio8863 I gave up bread years ago and do not eat sugars much. Never had a ´´soda´´ in my life.

[@lauradiaz1888]

My mom has Alzheimer’s and she’s 98 years old. She is having issues with UTIs. It is always amazing how little they study women’s health issues. They can send a man to the moon but they cannot figure Oita UTI or Alzheimer’s!

[@estherg7128]

I couldn't agree more! My aunt has Alzheimer's and constant UTIs. Her baseline seems to have a higher bacteria CFU than the average person. As it creeps up, it absolutely impacts her. When she has a full blown infection then she is nuts. I don't know why more folks aren't studying this connection and also understanding the microbiome connection related to this.

[@gretchensaaduddin5123]

Hasn't her doctor told her about taking the supplement D Mannose? Wash with water after every urination, and b.m. Then wipe with coconut oil. Make sure she knows how to wipe herself too. She will do much better. My Mom had a wonderful urologist and she was an active 97 year old.

[@bamanana2922]

Is D Mannose something your mom took every day as a preventative? Thank you.❤

[@WaningGibbous]

Cranberry is a great thing to prevent u.t.i.'s

[@gretchensaaduddin5123]

@@bamanana2922 Yes!

[@AnyPerson-my8pe]

I read her new book, The Menopause Brain, last night, so I'm eager to hear this interview - thank you, @rich roll!

[@tamic193]

This is such an important topic that gets so little attention and as a woman I am so appreciative of the time you devoted to this. Thank you to both of you!

[@SculptExpress-gv8jp]

Absolutely and she is so knowledgeable!

[@jennifermuse9154]

I hope she looks into the role of cholesterol medication and Early Onset Alzheimer’s. It would be great to have her as a guest again.

[@arlenegarza4353]

Never get on cholesterol meds. U need cholesterol. It's sugar needed to avoid but translate must get rid of tons of garlic. A week helps supps

[@dessaarnold7540]

Definitely!

[@rikae623]

The medication gets rid of the cholesterol in the brain which the brain needs. The medication job is to pull the cholesterol from the body and of course can’t differentiate where to pull it from

[@adunzoroq33]

How does this video not have millions of views! Wealth of knowledge, thank you !

[@erindowling8540]

Im 70 and never had one symptom of menopause, except for the obvious of no monthly period. I feel absolutely great, while I watched all my friends suffer with night sweats and being irritable. Ive always eaten very healthy with lots of fruits and veggies, but I also eat meat, mostly red meat. Ive always been active too. I have always eaten a lot of sugar but never have had high blood sugar. I eat a lot of salt too, always the kind with iodine added. Chocolate being my favorite. My mom and sisters were the same way. I have wondered why.

[@lindajones4849]

The coauthor of the book " Estrogen Matters" also mentioned that she had no menopausal symptoms other than the obvious sign that her periods stopped. Same with her mother . Apparently a small number of women do not have symptoms , but the majority of women do have symptoms . So congrats on your genetics. Also watch out for that high sugar diet, you may not get away with that for your entire life. A coworker of mine was diagnosed with diabetes in her 60s. She was quite active , normal weight , ate healthy with the exception of high sugar desserts at lunch and dinner. Get both your fasting blood sugar and fasting and insulin levels checked.

[@bevturner2258]

I’m 72 and never had any menopausal symptoms either, same with my sister. I’m not particularly health conscious although I do avoid processed food. Has to be said, I love dark chocolate 😊

[@erindowling8540]

@@lindajones4849, I'm almost 71 and don't eat a lot of sugar at a time but I do eat some sugar every day, mostly dark chocolate. I always keep a yearly check on my sugar. My mom lived a healthy life til 96, and she ate more sugar than I did, so I'm sure it's something genetic.

[@arlenegarza4353]

Iodine

[@arlenegarza4353]

Cocoa is a nituc oxide produces blood flow

[@jeristowell2635]

Thank you, Dr. Lisa for talking about eating plants, exercising, sleep, and HRT.

[@singingway]

45:58 "you don't react to negative things as much, so you can sustain happiness longer." that is so true. I can't even sustain appropriate anger, it just melts away!

[@bigbeautifulsky]

I have a supplement regimen I have to take to get through pre-menopause. Women NEED certain supplements to survive this transition, and they are well-documented. You can use supplements to help boost certain hormone levels. As much as I enjoyed this interview, it lacked nutritional information, which is KEY to staying healthy during menopause. While she did talk about diet, a lot was missing, especially around cortisol levels and their effect on brain health and female hormones. For many women, high-intensity exercise is not helpful during menopause because of the elevated cortisol levels it produces.

[@wolf4076]

Where is the best source of supplement info for menopausal women? Thank you.

[@dessaarnold7540]

​@@wolf4076you might check into herbs. I did take Valarium,spell check that., for mood swings. But now at 68, ketovore has had the most impact for me physically and mentally.

[@meredithheath5272]

Thanks for the reminder (- you sound very educated❤) cortisol does increase with exercise. (Damned if you do - damned if you don't... )

[@Elena-fe3os]

@@wolf4076 ask your doctor.. I take calcium, magnesium, C, D , omega 3, collagen, estrogen, B, K..other plant based..Some, daily, some not. Try to get vitamins from a diversified diet. Exercise your body and mind. Nuts are good for brain..

[@696969bold]

I'd love to see research on the impact of Wild Yam Root on regulating the symptoms of perimenopause and long term effects on neuroendocrine hormone functioning as protective factors against Alzheimers/Dementia.

[@juditrotter5176]

Bastyr University is a school that has degrees in naturopathic medicine, acupuncture and Chinese medicine, and nutrition. They do lots of research as well.

[@sharievangilder6436]

Research Barbara O'Neill she talks alot about wild yam cream.

[@696969bold]

@sharievangilder6436 thank you kindly for your response. If I recall correctly, Barbara O'Neil is an Australian nurse. I'm not familiar if she has any published research on her work.

[@Threadbow]

​@696969bold also iron and b12 are key and can get you better if caught early enough

[@696969bold]

@Threadbow indeed. MTHFR snp led to B, glycine, and glutathione supplements. Endocrine is one the most complex systems. Recognizing systems are integrated parts to a whole is one key to seeing health.

[@Leashhillery]

I am so grateful that men like you with your platform are interviewing experts in menopause. As someone currently going through this myself it was quite alarming to discover that my GP really had zero idea about menopause and how to help me. It was even more concerning to find that hardly any research has ever been conducted! So thank you for taking the time, hopefully we can get more information out there circulating not just to medical practitioners but also to females themselves, so they can go into an appointment armed with correct knowledge

[@deechristensen8188]

Totally agree, but sadly I went into my own GP respectfully armed with founded research, studies proven with changes in estrogen during menopause and the personal effects to my own health and was treated like I was challenging his qualification. Conventional medicine education needs a huge shift in both attitude and openness to learning. Thank you for bringing this well neglected, yet ever growing women’s health concern out in discussing in this safe forum. And ladies … NEVER underestimate your own womanly intuition … least of all with a foggy brain.

[@user-zx5vr8xr9q]

Absolutely agree! I'm a 52 year old woman (in Aus) and the information shared in this interview was very relevant to me. I really like the way you interview, Rich, intelligent, thought-provoking questions and your guest was so incredibly easy to listen to and knowledgeable. I love that you don't talk down to your audience. Im sharing it with my community.❤ wishing I could get my brain scanned too! Would love to talk to her about endometriosis, estrogen and alzheimers.

[@envejeceresopcional]

In 2020 I was 49 I changed my lifestyle and now almost 53 I’m in The best shape mentally physical

[@iskierka662]

I agree that diet and life style play a big role in menopause symptoms. I don't eat processed food, white sugar, junk food and I sleep 8-9 hours every night. There is plenty of seafood, veggies and fruit in my diet. I entered menopause at the age of 56 and I don't recall many perimenopause symptoms. My hot flushes lasted maybe few months and now at age 57 I only get occasional sweating. I don't take any HRT, just some homeopathic drops. I also hike in the mountains each week 8-10km and exercise at home for 20-30 min 2-3 times a week.

[@stargazerbird]

I am seeing my mother in in law in early stage dementia. Her husband is four years older and although is frail has no sign of mental decline. Her younger sister is further along. Neither is on HRT. I am 70 and have been on BHRT since 51 and my first week of hot flushes. So far I am still mentally sharp. I will never be without. I saw my mother suffer after 50 with never sleeping through the night afterwards. Just the lack of enough quality sleep damages our health and mental robustness. Go on the old menopause forums and read. This causes suicide, marriage breakups, long term suffering both emotional and physical.

[@squishysirenita]

I can listen to her forever!!!!! Her voice, tone, the way she explains everything is so perfect!!! Also...am I the only one to pick up on their chemistry??🙈😏

[@ikkahackinen9008]

I found her flirting annoying! That constant effort from her side to provoke that energy kills the effect of the good conversation.

[@marianapopescu753]

They both married l suppose, but yes,l noticed her flirting during the interview

[@MrBendinho]

totally flirty!

[@Inna-hp1uc]

I noticed that too

[@soosie69]

I became vegan not long after my early-ish menopause and I have had no symptoms. In fact I feel better now than when I was premenopausal. Plants are just amazing, I love learning about how magical they are at keeping our bodies healthy. Thank you this highly informative interview. What a lovely lady Dr Lisa Misconi is. I love how she is so passionate about her work.

[@madelinebrennan7603]

I also want to comment on Dr. Mosconi's observations about how so many women--of my generation and prior--have been so poorly prepared for the totality of what menopause involves. I was in a doctoral program in clinical psychology in my mid-forties, and I remember going to my male advisor when I was rather distraught because I could feel that my brain was not functioning for me at the level it always had. He sort of...poo pooed my experience, which felt extremely invalidating and dismissive. I not only knew my brain well, but because I was smart, had IDENTIFIED strongly with my good brain all my life, and so was keenly aware of when that good brain was not functioning well. All I had heard prior to this about menopause concerned hot flashes and night sweats, and it's STILL largely what I hear in media marketing products to address menopausal change. But do you know what? Menopause to me was nothing less than a shattering of my identity. I was so ill prepared for this and find that...infuriating. Thank you, Dr. Mosconi, for your research. I would love to meet you one day and thank you in person for validating the experiences of centuries, if not millennia, of women everywhere. F#CK! It's about time, right??

[@stephaniehalo7005]

I agree with this statement so profoundly! I hit early menopause at 43 and my (male) doctor kept telling me I was too young. I said I knew my body and was never off cycle and I could not sleep, was waking up covered in sweat and having hot flashes every 15 minutes. I knew something was not right. 6 months later, he finally tested me. My hormones were at a post menopausal level. He put me on HRT because I was having so many issues. Soon after, I woke up with SSHNL in my left ear. After many therapies(steroids, shots in my ear, and hyperbaric oxygen) I got most of my hearing back. I have read that low estrogen from menopause can be a culprit. I also started having mental decline and it is to a point that I am worried I will have major issues as I age. I am taking supplements, have changed my diet and 3 years later, I woke up with the same sshnl in the same ear. Still no doctors know why as of now. Going through the same treatments. I also broke my ankle and have fallen a few times down steps and off a ladder. Who knew that my life would be over at 48? It started at 43, but now I see that life was good, then life was bad. I feel bad for my husband because I snap at him cause I am angry when I can't recall words or I say left when my brain was thinking right. I do not have a history of dementia in my family. I'm not sure if that matters. I got my period at 11 and it was intense. It hit me hard. I was angry and I remember going to a park called Mother Goose Land and telling my mom, "I'm too big for this now. I can't have fun here anymore." So, I guess I shouldn't be surprised that I feel this way when the hormones left me. I am not on anything currently and wonder if I should be, but am upset that there are not menopause clinics. There should be! People tell you NOTHING about what this might be like other than the jokes of hot flashes, which I try to tell my friends are not funny. They think that no periods will be fun. I tell them to embrace them because my life ended when they did.

[@madelinebrennan7603]

@@stephaniehalo7005 I can see we had very similar menopause "takeovers." I can only tell you that (a) as my mother-in-law told me, my brain fog would get better/ease. It's not totally back to baseline but yes, it is MUCH better than it was when I was in the middle of it (about 5 years in, like you), and (b) if I were just 5 years in like you, I'd do what people suggested to me and see my gynecologist about HRT b/c it's too late for me now (12 years later). Effects would likely range from neutral to negative but research (as her meta-analysis demonstrated) suggested you will benefit from HRT now. I am not a doctor--I'm only suggesting that I personally think it is worth seeing your gynecologist about since you're only 5 years in. Take care. Thanks for sharing. I LOVE your idea of Menopause Clinics by the way!!!

[@jilla2650]

I did a PhD in my late 20s. My mind was very sharp and I could retain a lot of information easily. I am now 49 and starting a new business. My mind and memory are so dull, I can really see my disability. I have not hit menopause, but look forward to trying HRT to see if I can improve my cognition.

[@madelinebrennan7603]

@@jilla2650 I hope it helps. Friends have said it helps primarily with things like hot flashes rather than memory/mind fog. I learned in grad school to just adjust to my new baseline, but in later years, the brain fog dissipated naturally to a large degree. That was reassuring. I'm an actor now. I just have to work 7 times harder (arbitrary number, lol!) to memorize lines than I used to but I can still do it :) Best...

[@wendyfarrowartist]

Lisa is doing much needed research and I thank her for that. This was an excellent interview. I imagine this is covered in her books so I will read them, but nothing was said about actually building your grey matter by learning new things. My mom was always keen on studying new subjects, doing memory testing puzzles, and reading… a lot. She was as bright as she was in her 40s until the day she died in her 90s. I am 62 and relearning algebra, calculus, and brushing up on my French and starting to learn quantum mechanics. Creating new connections in the brain and keeping all of its modalities sharp is just as important as all the other steps she discussed. I feel very lucky that I did not have any menopausal difficulties, not a single hot flash or any cognitive issues. I have always had a highly plant based diet and almost no processed foods so maybe that has contributed. Thanks again for such an informative talk.

[@lezlieheller217]

I have appreciated so many of your interviews but this is my favorite. It may be because I am 66 and am aware that I am losing my mind! Family and friends are aware also. Dr. Mosconi is an amazing communicator and her work is fascinating and so important. Thank you so much for this.

[@jbean4176]

Prayers for healing 🙏🏻

[@Iamthepossum]

I’m so sorry to hear that; may I ask how you “know” you are “losing your mind”? I ask in all kindness and sincerity, as I am also age 52 and have gone through an early menopause, and have noticed some mental & emotional changes as well. Take care & peace to you ❤

[@keepingitreal618]

The fact is that you know your losing your mind, my parents had 0 understanding that they had alzheimers.

[@user-zo8ey9ee7n]

Thank you for this beautiful podcast ❤

[@lezlieheller217]

@@Iamthepossum one way is because of comments from family. I can’t tell you how often I hear we just discussed that mom. Or don’t you remember you just told me that a few minutes ago. I also have memory lapses. They tell me things that we all did together and I have no memory of it. It could’ve been a long time ago. It could’ve been yesterday. Google Calendar is my friend as keeping notes and making lists. I can function, but a lot of things fall through the cracks.

[@bagel_bandanna]

At 58:00, she starts talking about surgical menopause. Important to point out here that the treatment of hormone receptor positive breast cancer often includes surgical menopause or chemically induce menopause, followed by aromatase inhibitor medication which reduces estrogen levels to undetectable levels. The woman can go from premenoausal to no detectable estradiol within weeks. The cognitive implications of this are generally not disiclosed to patients, especially to low risk patients who may be sacrificing bone density and cognitive functioning for a small reduction in the risk of occurrance of breast cancer.

[@arlenegarza4353]

Not to mention getting on d3 n k2 mk7

[@questioneverything1776]

This is such an important comment. Estrogen is not the enemy of our bodies and affects the structure and function of ALL our body organs. If a man were to get their testes removed you bet they would replace his testosterone but WHY are female hormones demonized? The fear porn around female hormones is disgusting and there IS a difference between 17-beta estradiol (bioidentical) and the other, including the difference between micronized progesterone (bioidentical) and progestins. Most studies are done with non-bioidentical hormones. Also, the importance and safety of transdermal estradiol administration vs oral administration.

[@sandralewis-hy3no]

Why are women treated like 2nd class citizens when it comes to health? It's not easy getting access to HRT in the UK, we are half the b***dy population for goodness sakes! Thanks to the work of Dr Mosconi for the research, this could save a lot of people, she is truly making a difference.

[@rebeccastora8398]

Yes! MTNBC patient here. Medically induced Menopause is absolutely miserable. No one is discussing it, or trying to help us prevent the medical outcomes that can develop due to the outcomes related to Chemotherapy. If cancer doesn’t kill us, the side effects do.

[@dianaleedelight]

Have never felt so alive since menopause. Had my period later, after 14 years old, my life was uncomplicated until I started to menstruate.

[@hnttakata713]

Thanks Rich for being concerned about woman’s health

[@pancharutnamkrishnamoorthy4961]

Meditation should be considered in our opinion against Dementia

[@ozmonto]

Such a fabulously informative video. I could listen to her speak all day! She’s incredibly intelligent and clear in conveying her knowledge, research and dogged passion. Such a wonderful discussion❤

[@ranaparker4825]

This info is so important, it can save a lot of money in medical testing and care! In my mid 40’s, I began to have neuropathic symptoms, sensations like pins and needles. I saw several docs including neurologists and even had MRI of brain. Not one of those docs ever asked me if I was in perimenopause or menopause. Come to find out, this is a symptom of menopause. The only upside is now I have a baseline mri of my brain!

[@elonas9487]

Oh wow! This happens to me a lot. It improved when I started taking iron, but I still have it sometimes. It started when I was about 36. I felt my hormones were wildly out of whack at that time. I am 46 now and the episodes are much fewer, but I didn't know about the association with perimenopause, which I am in right now.

[@susannabezooyen2428]

Great information. So grateful Lisa joined you for this discussion.

[@claudieharris9046]

She is SO WONDERFUL !! My favorite part is her suggested best diet for brain health. Thanks to both of you!

[@realplanet]

1:18:00 Aamla - the Indian Gooseberries, we Indians swear by it ❤. It's that healthy 😊😊.

[@annetteyoutube742]

Lisa mentioned a Dr Roberta (can't remember last name). I heard her lecture on an Alzheimer's Summit, and she said that when women transition into menopause, the brain becomes inefficient at using glucose for energy. To overcome this, women should eat adequate protein (which will become the primary energy source for the brain during this transition). If they don't, this energy-deprived brain can present with dementia-like symptoms. I don't know what type of (permanent or temporary?) damage this can cause the brain, and I don't know if men's brains also benefit from adequate protein intake. But many aging men and women often don't consume adequate protein, so this should be a consistent education piece for a healthy brain.

[@dessaarnold7540]

Especially if you're in a nursing home or hospital. The sad diet is indeed sad!

[@rosemaryblundell5389]

Dr Roberta Diaz Brinton

[@the_fruit_2491]

I totally agree with you here! I have always heard that adequate protein is key! You cannot get all of the ESSENTIAL amino acids and fatty acids that come in the form of meat, through plants! It just is not possible! They don’t exist in plants. So pushing a plant, heavy diet is a little skeptical for me. I eat some plants and some fruits, but I make sure I’m hitting adequate amounts of protein daily! most elderly and older population do not get nearly enough protein in their diet. Also, you cannot get all of your essential vitamins through mostly plants. Meat, of all origins, healthy, fat, are 100% necessary to survive! You do not need plants to survive, just fact! So, in her healthy explanation, I wish you would’ve added and talked about the fact that you cannot hit all of your nutrition goals mostly through plants, you need adequate animal protein.🤷🏻‍♀️ I am 60 years old, very healthy, extremely active and flu through menopause at the age of 53.

[@neilbush9873]

I used to read various books on relationships as a young man but it was all about young people. I lived in dread about what would happen to my young wife when this time of life would possibly wreck our sex life or worse. Even today its rare to find helpfull information beyond the inadequate hormone change explanation, as if knowing biology will help us to be supportive .We are in our early 60s now and I think I am beginning to understand some of the things I needed to know. THANK YOU FOR RESEARCHING THIS BLANK GAP IN OUR UNDERSTANDING

[@sumernoel1553]

I can personally attest to the struggle of shifting hormones. I am finally pursuing HRT for relief & it is helping. Quite fascinating. However, finding a good practitioner is difficult depending where you are & ITS NOT COVERED BY INSURANCE. Let me repeat: CRITICAL WOMENS HEALTHCARE IS NOT COVERED BY INSURANCE OR TRADITIONAL MEDICINE. I am fortunate to have the means at this time to pursue this but I’m pretty sure that I’m the minority. How many women suffer through this transition without help? How many of our mothers & grandmothers suffered terribly because there was nothing available to help them? Instead, we’re labeled crazy.

[@silviadamen8847]

Midi Health is covered by MANY insurances. Finally! Now we just need the hormone options to be fully covered by insurance - but general estrogen and progesterone should be covered. Still waiting for testosterone for women to be covered!

[@justbeegreen]

Infuriating.

[@LadyBug1967]

Noel, are u using bio identical hormone replacement or the chemically derived sort, ie premarin etc?

[@justbeegreen]

@@LadyBug1967 I’ve found that the bio-identical hormones are difficult to administer bc people usually get it otc or people who are selling it have no way of measuring it in your system. I feel like there has been - thankfully- enough longevity studies to see the impact of HRT - and the prescription level can be adjusted depending on the individual’s body’s needs. I am looking into it. Good luck with your transition. 🍀

[@suebradford7772]

I watched this last night and it was amazing! So much information I wish I had known 20 plus years ago. Sadly, I am almost 70 and never had HRT. Is there anything I can do or take at this point in my life? I realize diet and exercise are key and I’m doing that, but looking for more if possible…

[@MissLizaYangonMyanmar]

Thank you for this. Going through menopause now. People are still so ignorant of everything around this topic. Many needlessly suffer. Fortunately, I knew how to advocate for my health to get the care I need.

[@lindajones4849]

Congrats for getting them to give you estrogen .How did you get them to listen to you?

[@vielsafttrank7582]

What kind of care do you mean specifically?

[@catherinekasmer9905]

I think it’s important to note that studies of women taking HRT looked at people who do not eat optimally. It’s important to note also that reducing the risk by 30% means that many other things are going on. I really distrust pulls as the answer. We do not have a full answer here but please note that an optimal diet impacts hormone levels as well. I personally would never take added hormones. I think it is hubris to make any claims that scientists know all the effects of overriding a complex messaging system of hormones over the lifespan. The overarching truth is that science, under the influence of a pharma industry whose main goal is making money, has a dismal record when it comes to dosing women with hormones. I would suggest getting one’s own body in tip top condition so that its own systems of regulation can function properly. It’s like the fact that eating greens mitigates some of the risk from smoking. That doesn’t mean the primary intervention shouldn’t be getting rid of smoking. Begin with optimal lifestyle- and not a half-assed watered-down approach. People deserve to know that a fully compliant WFPB diet with an hour of daily activity that is mostly zone2-3, but also includes vigorous zone aerobic, strength training, stretching and balance activity is what is required. Right- that’s not how modern American work life works. It takes a lot of time. Still, this is what is needed to be healthy- along with lifelong learning, social connections and serious stress mitigation. We are living in a sick sick society so it takes a lot of effort just to normalize our body/mind/heart. After getting sick I needed to radically re-assess my material standards in order to prioritize wellness. Sadly our medical institutions are not giving correct information, so step one is educating yourself. It is shocking to discover that moneyed interests actually spend millions to block research and dissemination of the truth. Try the correct, fully compliant WFPB diet diets and add in a full complement of movement. Do this fully for a year. Then let’s talk.

[@Hasmiral]

I strongly disagree. A third of menopausal women suffer from severest symptoms, although they don't drink or smoke and eat orthorexically well, like me. I was totally fine having a sixpack until my mid forties until my hormones fluctuated and I was also mentally a wreck. After taking all 3 necessary hormones I slowly recovered and got my "brain" back, I got my energy and stamina to do my job effectively again, got rid of brain fog and heart palpitations and be able to lift heavy again 4-5 times a week. Not every woman is equal healthwise. I am "back" since I got my hormones back and I am thankful for that every day. This is my case only. Can*t speak for the rest of menopausal women.

[@Lil33bit]

Fair enough, but I strongly agree. Just goes to show how different we are eh

[@EadsB7002]

Yes!! i wholeheartedly agree!! i hate that so many women use HRT as more of a band-aid than a last resort... Eating WFPB/avoid alcohol, exercise (cardio and weight bearing) consistently, manage stress, and continue to challenge the brain well past "retirement" years...and i honestly believe there would not be nearly as much of a need for HRT. It should be utilized more as a last resort than just something we just "take for menopause". Sure, there are some who might do everything right and still need some "help"...but this is not the case for the vast majority, especially in the US.

[@jeaninesilva5055]

My mother took hormones until she was 83...she really hated how she felt when they were discontinued. I on the other hand went cold turkey...my heart went crazy when i was going through menopause so i was given hrt which made my hormonal migraines come back so i quit the hrt and my heart calmed down.

[@blueyomogi]

This is such a valuable interview especially since I was just contacted about participating in a brain study from UCSF and also because I was offered HRT from my primary care physician.

[@running4fun863]

This is one of the best informative Podcast ever watched. I am quite worried as I was a baby that was dumped , no family history, abused while in care and I feel recently i am becoming very angry with the things that has happened to me, crying alot and than feeling terrible that I do not want to talk to anyone . Are these sighns . well they only thing I have control of is my health so I stay very fit. Hope this helps me.

[@susanne1756]

Many of us were dumped... I was, too..! It took me most of my adult like to deal with this. I'm 72 now, and I've finally made peace with this. Taking a DNA test and finding out what your heritage is, plus meeting your bio family, really helps. We wouldn't be here if we weren't meant to be. Do something you love, find peace in small places ❤ And remember to thank the woman who gave YOU LIFE...at least in your heart.

[@rgdden2702]

+JMJ+🙏

[@sunshinedayz2172]

My life has a similar thread.. I have sought answers from my creator. And found that through his son there was healing and deliverance.💕💕

[@franzsidney865]

I think you have many suppressed emotions derived by the lack of love and acceptance. This is not hormonal but emotional and I am sure if you work with a therapist you will be able to release negative emotions and feel much better.

[@dessaarnold7540]

I am finding help with therapy on utube for childhood trauma. You are not alone.

[@Suzanne291]

It is quite an adjustment to get through menopause but once complete it is indeed a happier life. I feel more confident, peaceful, wise and most importantly I just dont care about things that dont matter. It is like I can see the trees through the forest. I will add that I could not get rid of the brain fog until I started the bio-identical estrogen patch. Thank you for the this wonderful guest, Dr. Lisa is wonderful & brilliant.

[@HannahHarbourDeep]

I feel the same. I would never want to go back to my hormone brain. It seemed like it hijacked my spirit and now, with faith, there is peace and wisdom. May I ask which bio-identical estrogen patch you use?

[@Suzanne291]

Estradiol@@HannahHarbourDeep

[@anne-mareehern]

Thank you for a very informative, trust worthy interview. Also thank you so Lisa for all your fabulous work, dedication and passion.

[@trishstauble3461]

I feel so bad for young women who get involved with carnivore diets. I hope their microbiome recovers and they can flourish...if only we had more research done on women...thank you, Dr. Mosconi for your efforts. Thank you Rich for hosting her on your show. Glad to hear the science on how fiber and anti-oxidants help my brain out !!!! WFPB at 70 for 4 years !

[@tatywork9126]

where did she talk about meat?

[@trishstauble3461]

In her anti-oxidant comments about the brain burning glucose and how that causes oxidative stress to the brain. She said plants are high in anti-oxidants and meats are low. She said meat also has no fiber which does so many things for us including estrogen regulation. @@tatywork9126

[@jenniferflaherty730]

I put my burger down to listen to this interview. It was awesome!!! And my burger was awesome too. TWO truths can exist at the same time.

[@sumernoel1553]

Dr. Jill Biden’s next initiative is increasing funding & research for Women’s Health! Much needed! We need women’s health to be studied & be fully included for insurance.

[@zonderbaar]

Carnivore increases gut health and gut flora biodiversity 😊

[@annaderoo8378]

6 questions: 1. Why don't you mention that not all women experience menopause symptoms? 2. Why are there no studies of what lifestyle elements women who do not have any menopause symptoms have in common ? 3. Given the existence of the nocebo effect, to which extent do women develop symptoms because they are continuously told to expect them? 4. Given the fact that current altzheimers figures mostly relate to a generation of women who were less intellectually, professionally and athletically active than men, and also generally more oppressed and less free, isn't it likely that the brain decline noticed after menopause is caused at least partially by the fact that these factors speed up mental decline as one ages? 5. How much money would doctors lose if women were symptom-free naturally? 6. How much money would the pharma industry lose?

[@bevturner2258]

I’m one of those fortunate women who had no symptoms going through menopause. My mother, on the other hand, had a terrible time with night sweats. I’ve always wondered why some women sail through and some suffer. My sister had no symptoms either and interestingly, we’re very different. Different lifestyles, different personalities and different bodies too. Unfortunately nobody is going to fund a study on why some women don’t have any symptoms of menopause, no matter how worthwhile…

[@annaderoo8378]

@Bevturner2258, same same, am 60, no symptoms ever whatsoever, contrary to sisters and mom. I just get irritated that scientists with big social media platforms don't even bother mentioning that that is a possibility and barely touch on the impact of lifestyle and diet. As if they are all sponsored by big pharma. And of course no studies are done of what women with no symptoms have in common, for no money to be made that way. Am just venting my irritation each time I come across an interview that represents a pharmaceutical solution as necessary. In the hope at least one younger woman reads this and knows it is not necessarily to be scared. And again, I recommend every one read up on the nocebo effect.

[@bevturner2258]

@@annaderoo8378 Yes!

[@whoolawoop6817]

Thank you, for pointing this out! ❤

[@whoolawoop6817]

Years ago I saw a film about Alzheimers and it discussed a study they did on nuns (I think in Italy or Switzerland) ... The nuns took part in this scientific research project and even gave their brains (after death) to do autopsies. Many of those brains looked exactly like those of Alzheimers patients, but none of the nuns ever showed any symptoms! They lived a perfectly healthy life within their rather strictly regulated and very structured environment. So the conclusion was, that dementia is not so much a matter of plaques in our brains, but a matter of establishing nurturing routines and staying active in a largely supporting environment...

[@megm.c4026]

So what about Chris Palmers work re carnivore/keto diet to reverse dementia and mental health issues?

[@dessaarnold7540]

I haven't heard of Chris palmer, but watch many other keto, carnivore, bloggers. It has made a difference in my life.

[@megm.c4026]

@@dessaarnold7540 check him out. Hes a psychiatrist at stanford uni and has miraculous results with keto diet. Interesting guy. Dr Chris Palmer.

[@vanessas2363]

Fantastic subject and guest! This was meant to find me this morning. I will be watching in parts. I am 48 years old, and went through premature menopause starting at 26, (medics didn't believe me) and i was on HRT by 30. The whole thing had a devastating impact on me physically and psychologically. I am the only female with 3 male siblings. My paternal grandmother died at 76 (I was 11) and she had advanced Alzheimers. Her son, my father, developed Parkinson's and related dementia in his mid 60s and died at 70 from a fall. I am concerned about how taking synthetic hormones for nearly 20 years has had a negative impact on my body and brain? But I'm more concerned about how I might develop dementia. They call it 'the change' for a reason, I was never the same again, especially my cognitive functioning. It still makes me sad.

[@majahorvat7294]

Ketogenic diet has helped many people with their cognitive function. Also you might be interested looking into photobiomodulation. There are KZbin videos on it, it has very positive effects on cognitive functioning. I hope you start feeling better soon.

[@IResonateWithU]

I have both Alzheimers and Parkinsons in my family as well. Stay brave 💛🌤

[@Geogaddii]

Sorry to hear how you were mistreated by the medical institutions that should have helped you! Ironically, only a brain scan can address your concerns. Otherwise, stay healthy, consume antioxidants and keep stress down :) you’re better off not worrying for 10 years than worrying and increasing your risk! If you are able to get healthcare, I would.

[@Lil33bit]

Hi sister Vanessa, glad you dropped your comment so I could drop this reply (me too I’m 48 & up against it but not as pronounced of a struggle as you’ve had); 1. I used one of the DNA/family tree sites to determine my APOE (or whatever the Alzheimer’s gene is called) status. 2. Dr. Bredesen has the most inspiring stories of ppl reversing Alzheimer’s, and I’ve personally witnessed a few ppl do a 180° and recover their brains. Phenomenal stuff. 3. Fasting has been the most efficient (I’m not a dr but I feel it’s efficient, it’s definitely effective) way to fix brain fog/memory issues. You probably already know this but I thought I’d write it anyways. Be well.

[@vanessas2363]

Wow, I came in from shopping and got such a surprise at all these lovely comments. Thank you so much! Very grateful for all the support and encouragement, and advice. 🥰 thank you! I'm so pleased I found this video today. Feeling positive! It's a worry for us all, our bodies are so complex. Take care everyone! 😊❤

[@jsingh108]

Great interview! There is another element I think that should be brought up.. trauma unprocessing and it’s effect on dementia

[@anewagora]

I am a detrans woman after being a transman for 14 years. I can't produce any hormones, and my estrogen was too low for a while, which put me into menopause at 28 years old. I've had the right dose of estrogen for a few months but hot flashes have taken a long time to begin to subside. I noticed that my memory the last 6-8 months has been terrible. I blank out and dissociate often. I've had hot flashes that somewhat smoothed over after a month of estrogen but I still have them 3 months later. And when she mentioned panic attacks among a list of other symptoms of menopause I was stunned. One of the doctors I saw tried to say my hot flashes were panic attacks to dismiss it as not real. She was caught not listening to me describe the symptoms. And she has it backwards. I've had BOTH panic attacks and hot flashes. I know the difference and it's very obvious. This information is a miracle in my life and I will be showing it to the doctors, as every one of them hasn't listened to what I was saying and has been making careless incompetent mistakes.

[@jbean4176]

Thank you for helping to shine the light on the long-term health consequences of transitioning

[@dessaarnold7540]

I'm so sorry, I haven't trusted doctors for a long time. You might look up some of the doctors on utube that are teaching carnivore. It could possibly help you.

[@irishouston4103]

Thank you so much for sharing. This has been a serious concern of mine since these operations to transition started. I think I really became concerned after befriending a gentleman that was transitioning into a woman and how he would have these severe hot flashes. This is so sad.

[@vernonbonnie]

Relevant and necessary information. Wish I had heard this 20 years ago! All women need to listen to this.

[@alicejwho]

My lovely mother in law has awful dementia. She was on HRT for 25 years but had a standard diet and literally never moved unless she was going shopping for clothes or food. Now, shes so frail she is 6 stone and can no longer use her legs. Literally. Her bones and muscles are just disintegrating. And she is unable to finish one sentence. Its just awful. She was so glamorous too, with a cheeky sense of humour Wonderful lady. Very sad I haven't yet watched this as I'm off on a yet-again-rainy bike ride, but I'm looking forward to it. I have my fingers crossed that it wont be another video telling this healthy 58yr old, cycling, weightlifting, language-learning woman (with many other interests) to take HRT or I'm doomed!

[@keepingitreal618]

both of my parents were extremely active after 75 they didnt have a car always carried heavy shopping. my mother never sat down was always on the go. they both developed Alzeimers.

[@alicejwho]

@@keepingitreal618 sorry to hear that, its just awful. The thing is, there are so many contributing factors now, it's impossible to single out any one thing. And so much of it is unavoidable.

[@ummtaimann6819]

So I don’t understand why some doctors keep saying that hrt prevents Alzheimer’s and dementia as no one in my family ever took hrt and they live until their 90’s without any decline in their cognitive abilities and your mother in law is a proof that hrt doesn’t protect so maybe other things play a role in the development of dementia

[@drahaskell1]

Thank you both... I wish Dr. Mosconi would have spoken about a new term for Alzheimer's, Type III Diabetes, since blood sugar regulation wasn't spoken of. I understand that consuming cholesterol won't effect brain levels due to the blood brain barrier BUT all the glands secreting sex and adrenal hormones (steroid hormones) must absorb cholesterol as the template for making them. I wish more was presented comparing the synthetic Progestin vs the bio identical progesterone, with the Progestin being the primary culprit in the Women's Health Initiative study.... Thank you again...

[@dessaarnold7540]

Yes. I believe in this type 111 diabetes. My mom had dementia.

[@Laura-il5lo]

Great discussion! Thank you so much❤

[@OmaOlaOma]

I having lunch with a friend tomorrow who was recently diagnosed with early Alzheimer's. This popped into my feed at the perfect time. I did take notes. Especially informative after fifty minutes.Rich, good questions always indicate how prepared and educated you already are.

[@chandrakasakevich4657]

I suggest the work of Dr. Dale Bredesen too.

[@lindajones4849]

I agree, Dr Dale Bredesen has 3 published books on his treatment protocols . This protocol is not a quick fix pill, rather each person is assessed for which problems are causing their Alzheimer's. Best to start now with diet, exercise , sleep, stress reduction, assess for toxin exposure. START now, because when the disease advances it is harder to reverse especially since in advanced stages people don't understand why they need to eat right, exercise, do preventive measures such as brushing your teeth, floss.

[@robyncohen8542]

It would be great to hear from Dr Bredeson, Prof Rob Bikman, dr Lustig, the role of metabolic disorders, type 3 diabetes and the effects on the brain/alzheimers

[@daniep3100]

When my moms alzheimers advanced such that she couldn't refuse the flu shot (with thimerisol) we saw her most rapid decline within a couple weeks. After that she could barely walk, when walking was a huge point for her, almost compl etely stopped talking and for the first time seemed unsure who I was. There are a variety of things that seem to tip the scale. I studied everything I could find and took her in to my home so I could intervene for her. In her own life she made a lot of choices with food (high carb, non organic, very low in satursted fat and all fats) medicine (statins and antidepressants), lots if strong cleaning chemicals, and procedure such as hysterectomy that were likely unfavorable for her brain and nervous system. It is really such a tragic experience. I'm so glad more research is being done.

[@dessaarnold7540]

I have recently went through this with my Mama. It was horrific. I am so very sorry.

[@821dbt59]

Thank you for this discussion.

[@barbaraevans5593]

This was fabulous! Thank you so much for interviewing this wonderful lady!!

[@karenalford4025]

Thank you, absolutely crucial discussions!

[@christinadehayes6541]

Phenomenal interview. I found myself taking notes. While the women in my family have often been blessed with longevity, dementia often became a factor in their 80s and 90s. So grateful to have access to interviews like this and local health care providers that seem to be "up" on this topic, as I am still optimistic that I may be able to dodge this outcome later in life. "When it comes to brain health, quick fixes do not work."

[@JJOK1818-okthen]

Thank you SO much for this! 👏👏

[@amandapham1151]

what an amazing interview! thank you!

[@terrapreta1]

She is brilliant!!! So incredibly knowledgeable and communicates that knowledge well! And this is such important information. I have learned a ton!

[@NadjaLind]

thank you very much for the fantastic interview

[@sheriready1830]

Such an important conversation!! Thank you so much!

[@veronikasykes5276]

Another awesome interview Rich. Thank you !

[@staceydouglas757]

It would be interesting for you to contrast her diet recommendations with Sally Norton’s book, Toxic Superfoods for an alternative point of view on a beneficial foods. In wouldn’t recommend supplements or a diet to anyone until they had a hair analysis test and blood test done first.

[@catherinefonseca9467]

Just a fabulous listen thank you so much. As someone who is 51 does not take HRT but has always exercised and is focused on how I eat and move, working on sleep and reducing stress the fact these matters is great news.

[@janeforrest6838]

I’m 64 tiny build have osteoporosis do my best to keep active walk my dog daily lead a bust life love all fruits and vegetables but have bowel issues so need to be selective in the veg section.Dont drink or smoke and although I have health issues I very rarely get colds or bugs and am convinced it’s because I eat organic and grass fed meat and butter also at least 6/8 portions of fruit and veg each day plus organic eggs.The one area I’d say I struggle is with sleeping and that is definitely since the menopause which I went through from 51.Found this fascinating so thank you.

[@elcaseriocasarural-kn2hb]

Simple great! Thank you both.

[@carlf.9035]

How come some countries have cases of dementia higher than other countries? We need studies on geographical stats of dementia, etc, because I believe it boils down to more than diet but more regarding your environment and social atmosphere. I would like research on this nevertheless.

[@bevturner2258]

My mother is 96 and her brain is still sharp. She eats what she likes and doesn’t exercise. That said, she has never touched alcohol or tobacco and I wonder if there isn’t a clue there…

[@carlf.9035]

@@bevturner2258 interesting, good to know. Looks like your Mom is living the good life.

[@petravazanska5707]

Thank you so much for this...❤

[@cecitrigos5810]

This is so amazing. Thank u!

[@firefeethok_tui2355]

What a phenomenal discussion. Thank you! ❤

[@XeniaAidonopoulou]

We of course want to hear about the brain scan and results when you do it!!! What an excellent guest...

[@skippy6462]

My husband at 73 gets a solid 8 hours sleep a night. I'm lucky to get 5. Think it's my birthday if I get 6. It's rare indeed to get 7 and never again to enjoy 8+ hours. It's painful trying to get back to sleep. Anxiety/worrying. I'm 58. Although I'm post menopause about 9 years I'm now trying BHRT. It's been about 10 days so far and not helped so far. We see.

[@stargazerbird]

I took about a fortnight for it to kick in for me. When it did it was a huge relief.

[@aimee9478]

Even if 9 years post-meno is a bit on the late side, you're still good to go! And yep, you need a little bit more time. If you don't feel that it helps/it worsens things, don't give up, just consult with your doctor - maybe your recipe needs to be tweaked a bit.

[@thewhole_picture1743]

What is BHRT please? You're the second person that's mentioned it on here that I've seen and I thought the first one was a typo for HRT. Thanks.

[@kristirichards2249]

​@@thewhole_picture1743bioidentical hormone replacement.

[@Michelle-fe3vw]

Fabulous interview- learned so much🤗🤗🤗

[@jf1763]

We, as women, need more wonderful men, like Rich Roll, who would help to debunk these harmful myths from the past and support us for the wellbeing of the society, economy etc... And more courageous, passionate and knowledgeable women like Lisa Mosconi. Thank you very much for sharing this conversation and for all that you do!❤